Digital Commons Network^™

Focused Education On The Roles And Responsibilities Of The New Nurse During A Patient Emergency, Jeanette Canderozzi

Walden Dissertations and Doctoral Studies

Staff Education Project aimed to measure the knowledge and self-efficacy gained from a comprehensive telemetry educational program as part of the onboarding process for nurses. Purpose of this project was to evaluate the effectiveness of the focused training for the novice nurse as it relates to their knowledge and confidence of their roles and responsibilities in a clinical emergency by using the pre-and postsurvey.

Adjunctive Middle Meningeal Artery Embolization For Subdural Hematoma, Jason M. Davies, Jared Knopman, Maxim Mokin, Ameer E. Hassan, Robert E. Harbaugh, Alexander Khalessi, Jens Fiehler, Bradley A. Gross, Ramesh Grandhi, Jason Tarpley

School of Medicine Publications

Background Subacute and chronic subdural hematomas are common and frequently recur after surgical evacuation. The effect of adjunctive middle meningeal artery embolization on the risk of reoperation remains unclear.

Methods In a prospective, multicenter, interventional, adaptive-design trial, we randomly assigned patients with symptomatic subacute or chronic subdural hematoma with an indication for surgical evacuation to undergo middle meningeal artery embolization plus surgery (treatment group) or surgery alone (control group). The primary end point was hematoma recurrence or progression that led to repeat surgery within 90 days after the index treatment. The clinical secondary end point was deterioration of neurologic function …

A Class Of Stable Nonlinear Non-Hermitian Skin Modes, Hamed Ghaemi-Dizicheh

Physics & Astronomy Faculty Publications

The non-Hermitian skin effect (NHSE) is a well-known phenomenon in open topological systems that causes a large number of eigenstates to become localized at the boundary. Although many aspects of its theory have been investigated in linear systems, this phenomenon remains novel in nonlinear models. In the first step of this paper, we look at the conditions for the presence of quasi-skin modes in a semi-infinite, one-dimensional, nonlinear, nonreciprocal lattice. In the following phase, we explore the survival time of the quasi-skin mode in a finite nonlinear lattice with open edges. We study the dependency of the survival time on …

Readmissions And Death Rates In Patients With Chronic Obstructive Pulmonary Disease At Veterans Affairs Medical Centers, Adam Ikli

Walden Dissertations and Doctoral Studies

Readmissions and death rates can serve as indicators of performance in healthcare organizations and can reflect a lapse in staff performance particularly for patients with chronic obstructive pulmonary disease (COPD). The purpose of this quasi-experimental quantitative study was to determine the extent to which readmissions and death rates within 30 days of discharge for patients with COPD at selected Veterans Affairs (VA) medical centers, differed between 2015 and 2018. The transitions theory served as the theoretical framework for this study. The research questions evaluated readmissions and death rates for patients with the chronic obstructive pulmonary disease at VA medical centers …

Office Of Research, Economic Engagement And Outreach Update, November 20, 2024, Office Of Research, Economic Engagement And Outreach

Office of Research, Economic Engagement and Outreach

No abstract provided.

Phase I Dose Escalation Study Of Io-108, An Anti-Lilrb2 Antibody, In Patients With Advanced Solid Tumors, Matthew H Taylor, Aung Naing, John Powderly, Paul Woodard, Luke Chung, Wen Hong Lin, Hongyu Tian, Nathan Siemers, Hong Xiang, Rong Deng, Kyu Hong, Donna Valencia, Tao Huang, Ying Zhu, X Charlene Liao, Xiao Min Schebye, Manish R Patel

Faculty, Staff and Student Publications

Purpose: In this first-in-human dose escalation study, the safety and efficacy of IO-108, a fully human monoclonal antibody targeting leukocyte immunoglobulin-like receptor B2 (LILRB2), was investigated in patients with advanced solid tumors as monotherapy and in combination with pembrolizumab, an anti-programmed cell death protein 1 (PD-1) antibody.

Methods: The study included patients with histologically or cytologically confirmed advanced and relapsed solid tumors, with measurable disease by Response Evaluation Criteria In Solid Tumors (RECIST) V.1.1. Patients were treated with escalating doses of IO-108 every 3 weeks (Q3W) as monotherapy and in combination with pembrolizumab. Safety and tolerability were the primary objectives. …

Cladribine-Based Therapy For Acute Myeloid Leukemia In Child, Adolescent, And Early Young Adult Patients: The Md Anderson Cancer Center Experience, David Mccall, Shaikha Alqahtani, Moriah Budak, Irtiza Sheikh, Aaron E Fan, Ramya Ramakrishnan, Cesar Nunez, Michael Roth, Miriam B Garcia, Amber Gibson, Naval Daver, Sofia Garces, Nicholas J Short, Ghayas C Issa, Farhad Ravandi, Courtney D Dinardo, Guillermo Montalban Bravo, Guillermo Garcia-Manero, Branko Cuglievan, Tapan Kadia

Faculty, Staff and Student Publications

Background: Cladribine-based combination chemotherapy has demonstrated promising efficacy in patients with relapsed/refractory adult acute myeloid leukemia (AML), prompting its increased utilization in the frontline; in pediatrics, it has been typically reserved for relapsed or refractory cases. While fludarabine has been used more commonly as a purine analog in intensive regimens, cladribine may be an important alternative.

Methods: We performed a retrospective study at MD Anderson Cancer Center from January 2015 to July 2023, which included patients aged 1-21 years with refractory or relapsed AML who received cladribine outside of a transplant conditioning.

Results: A total of 30 patients were included, …

Gec Meeting Minutes For November 20, 2024, A-State General Education Committee

General Education Committee Minutes

No abstract provided.

The Ensemble Code As A Constructed Working Memory, Jacob Zepp

USF Tampa Graduate Theses and Dissertations

This dissertation formalizes and refines a new theory of ensemble coding: the Non-Selective Transfer Model. Within this theory, ensemble codes and subsequent summary judgments are the result of representations constructed over a subset of information that is encoded into working memory. The work begins with a brief review of current ideas present within the ensemble coding literature, followed by a set of formalized descriptions of ensemble coding theories that have been proposed. A discussion of relevant theories present in the working memory literature is also provided to motivate the structure of the subsequent model. The Non-Selective Transfer Model 2 is …

Construction And Evaluation Of A New Rat Reference Genome Assembly, Grcr8, From Long Reads And Long-Range Scaffolding, Kai Li, Melissa L Smith, J Chris Blazier, Kelli J Kochan, Jonathan M D Wood, Kerstin Howe, Anne E Kwitek, Melinda R Dwinell, Hao Chen, Julia L Ciosek, Patrick Masterson, Terence D Murphy, Theodore S Kalbfleisch, Peter A Doris

Faculty, Staff and Student Publications

We report the construction and analysis of a new reference genome assembly for Rattus norvegicus, the laboratory rat, a widely used experimental animal model organism. The assembly has been adopted as the rat reference assembly by the Genome Reference Consortium and is named GRCr8. The assembly has employed 40× Pacific Biosciences (PacBio) HiFi sequencing coverage and scaffolding using optical mapping and Hi-C. We used genomic DNA from a male BN/NHsdMcwi (BN) rat of the same strain and from the same colony as the prior reference assembly, mRatBN7.2. The assembly is at chromosome level with 98.7% of the sequence assigned …

University Band: November 20, 2024, Mack Wood, Christopher Bulding, Colby Powers, Jospeh Buczko, Ben Haushalter

School of Music Programs

Center for the Performing Arts

November 20, 2024

Wednesday Evening

8:00 p.m.

Collabrative Piano Recital: November 20, 2024, Illinois State University School Of Music

School of Music Programs

Kemp Recital Hall

November 20, 2024

Wednesday Evening

7:30 p.m.

Regarding Friendship In Place-Based Development For Colleges And Universities, Craig Mattson

University Faculty Publications and Creative Works

This paper addresses the phenomenon of colleges and universities that attempt to repair the reputation of higher education in American society by engaging long disregarded or damned neighbors. This engagement is both long overdue and deeply fraught, especially as predominantly white academic communities interact with Black and Brown organizations and neighborhoods. Drawing on interview data from qualitative interviews among predominantly white institutions and residents of color, this essay argues that one way to decolonize college and community partnerships would entail the practice friendship across institutional and ethnic lines.

Can Eggshells Indicate Stressor Exposure In Free-Range Laying Hens?, Helen E. Gray, Emma L. Malcolm, Katherine Herborn, David Armstrong, Jessica E. Martin, Lucy Asher

School of Biological and Marine Sciences

Finding effective ways to monitor laying hen welfare is challenging as UK flock sizes can reach 16,000 birds. Eggs provide potential for welfare monitoring, as they are a daily output with previous evidence of links to stress. We explored the associations between stressors and eggs using two complementary studies. In Study 1, hens experienced social or heat stressors and eggs were scored daily for defects in shell characteristics. All eggs were scored on a three-point scale: 1 (no defect); 2 (minor defects); or 3 (unsuitable for whole egg sale in the UK). Texture defects were higher after stress treatments and …

Situation And Challenges In Development Of China’S Commercial Aerospace, Chaofeng Huang, Chao Zhang, Jinge Li, Mengru Dong

Bulletin of Chinese Academy of Sciences (Chinese Version)

Commercial aerospace is an important support for the national aerospace power strategy and a “new growth engine” for economic development, serving as a strategic pivot to win the future competitive landscape. Currently, China’s commercial aerospace industry is facing a mixed and urgent situation. On the one hand, the international competition situation is severe, with frequency track resources being seized and squeezed, international rules being passively constrained, and global market breakthroughs being hindered. On the other hand, domestic development opportunities are highlighted. The multidimensional support of central local cooperation is constantly strengthening, and the development prospects driven by industrial demand are …

Suggestions On Expanding Application Scenarios Of Commercial Aerospace Market, Mengru Dong, Chaofeng Huang, Ningyi Yang, Yu Yao, Yafeng Qin

Bulletin of Chinese Academy of Sciences (Chinese Version)

Expanding the application scenarios of the commercial aerospace market is an inevitable requirement for promoting the transformation and upgrading of the space industry and achieving the strategic goal of becoming a leading space power. Currently, the development of China’s commercial aerospace is in a critical transition period from technological breakthroughs to market expansion. However, there are still problems such as insufficient participation of private enterprises, low penetration of consumer markets, and insufficient competitiveness in the international market, and a sustainable and benign commercial closed loop has not yet been formed. The study analyzes the current situation of commercial aerospace market …

Reflections On Improving Industrial Investment And Financing Environment To Promote Healthy Development Of Commercial Aerospace, Cuilin Wu, Chao Zhang, Quan Cheng, Hongyu Wu

Bulletin of Chinese Academy of Sciences (Chinese Version)

As a new frontier in global technological competition, the sustainable development of the commercial aerospace industry highly depends on a sound and efficient investment and financing environment. Although China’s commercial aerospace investment and financing system has achieved initial progress, it still faces multiple challenges, including imbalanced capital structure, insufficient risk-sharing mechanisms, and weakened market incentives, which constrain industrial innovation and competitiveness. This study systematically analyzes the current status and main challenges of China’s commercial aerospace investment and financing environment and draws on international experience to propose following optimization strategies. First, improve the structure of capital supply and expand diversified financing …

Analysis Of Status, Challenges, And Optimization Recommendations For China’S Commercial Space Policy Support System, Liming Ge, Zixuan Liu, Mingda Yang, Wenbin Ma

Bulletin of Chinese Academy of Sciences (Chinese Version)

As a strategic pillar in building a space power, commercial space has become a new frontier for global technological competition. The Chinese government and relevant regulatory authorities have introduced a series of multi-level policy documents, propelling the commercial space sector into a phase of vigorous development. This study systematically reviews the background, evolution, and implementation outcomes of China’s policy support system for commercial space. It is indicates that, in light of the goal of becoming a “space power” and the future industrial competition, China’s policy support system for commercial space still faces challenges such as ineffective policy implementation mechanisms, lack …

How Does Original And Disruptive Innovation Lead Modern Industrial System: Insights From Revolutionary Frontier Of Next-Generation Chip Manufacturing Technology, Jiang Yu, Yue Guo, Shiguang Li

Bulletin of Chinese Academy of Sciences (Chinese Version)

Original and disruptive innovation is the foundation for tackling key technological challenges and nurturing the development of new forms of productive forces. The breakthrough of FinFET (Fin field-effect transistor) technology, a frontier manufacturing process for chips, represents a typical example of original and disruptive innovation. This breakthrough extended Moore’s Law, catalyzed the transition of semiconductor manufacturing from 2D to 3D structures, and significantly advanced the global high-tech industry, positioning it at the core of international technological competition. This study reviews the breakthrough journey of FinFET technology, specifically focusing on its development stages from “scientific discovery—formation of new technological pathways—systematization of …

Beyond Innovation Paradox: Practices And Reflections On Promoting High-Quality Development Of Commercial Aerospace With Low Costs, Chao Zhang, Qianshu Shi, Binbin Meng, Quan Cheng, Jun Zhao, Weitao Wu

Bulletin of Chinese Academy of Sciences (Chinese Version)

Commercial spaceflight, as a national strategic emerging industry, is critical for seizing the high ground of the space economy and fostering new quality productive forces through its low-cost and high-quality development. Currently, international enterprises represented by SpaceX have gained a leading advantage through technological breakthroughs and business model innovations, posing severe challenges to China’s aerospace security and development. This study first analyzes the evolutionary trajectory of low-cost development in commercial spaceflight, then delves into the “low-cost vs. high-quality” innovation paradox faced by the traditional aerospace industry and its root causes. Building on this analysis, it examines the experiences of international …

Foundation, Challenges And Approaches To Deepen Brics Science, Technology And Innovation Cooperation In Context Of Brics Enlargement, Xiu Yang, Haitao Chen, Ci Fang, Ziran Jiang

Bulletin of Chinese Academy of Sciences (Chinese Version)

Deepening international science and technology innovation (STI) cooperation among BRICS countries is of great significance for empowering Global South and building a global S&T community. This study takes the ten BRICS countries in the expanded membership as the research object, deeply analyzes on deepening international STI cooperation among BRICS countries, and puts forward approaches and suggestions. Research indicates that BRICS countries have established a long-term, stable, and mature mechanism of international STI cooperation that provides an institutional guarantee for deepening international STI cooperation among BRICS countries. The rising impact of STI competence, the expanded scale of STI network, and increasingly …

Green Certificate Of “Lucid Waters And Lush Mountains” And The Yellow River Demonstration, Guangqian Wang, Deyu Zhong

Bulletin of Chinese Academy of Sciences (Chinese Version)

Guided by the “Lucid Waters and Lush Mountains are Invaluable Assets”, this work systematically studies the mechanism for realizing ecological value and proposes an implementation plan centered on a Green Certificate system for ecological assets, to be advanced in three stages. The Green Certificate serves as an objective and quantifiable proof of ecological assets, integrating four categories of ecological products—ecological water, soil and water conservation, carbon sequestration, and afforestation (grass planting)—into a unified, tradable rights certificate system. This provides an institutional foundation for transforming “Lucid Waters and Lush Mountains” into “Gold and Silver Mountains” through market mechanisms. Taking the Yellow …

Research On Strategies For High Quality Development Of New Power Systems, Xiaohong Chen, Junpeng Li, Yongmei Liu

Bulletin of Chinese Academy of Sciences (Chinese Version)

New power systems are at a critical stage of transition from theory to implementation. Against the backdrop of accelerating global energy transformation and technological revolution, shifting the energy system from “scale-oriented” to “quality-driven” is both an urgent need and a key focus for advancing the high-quality development of China’s new power systems. This study employs a four-dimensional analytical framework integrating “technology-elements-industry-green transition” to identify the main challenges existing in the new power systems currently, including constraints in key technologies, imbalances in factor allocation, difficulties in industrial coordination, and instability in power supply structure. Targeted measures are proposed accordingly. (1) Strengthening …

Coordination Degree Of Composite Systems And Its Application, Ke Qi, Jiaojun Zhu, Dexiong Teng, Xiao Zheng, Huaiqing Zhang

Bulletin of Chinese Academy of Sciences (Chinese Version)

A composite system (CS) is an organic whole composed of multiple subsystems. It has the property of operating in a coordinated manner through the interconnection and interaction between its subsystems, which could be evaluated by the indicator of coordination degree of composite systems (CDoCS). However, there is currently a lack of quantitative methods for CDoCS and the CDoCS-based technology for composite system optimization. As a result, there is a lack of effective solutions to the problems caused by the disharmony of composite systems such as the mountain-water-forest-farm-lake-grass-sand systems (i.e., composite ecosystems) and the social-economic-natural systems. Therefore, the connotation of CDoCS …

Research On Regional Suitability Assessment And Promotion Mechanisms Of Conservation—Based Utilization Models For Black Soil, Xiaojie Liu, Liangjie Xin, Jiliang Ma, Yuxian Wang, Fan Zhang

Bulletin of Chinese Academy of Sciences (Chinese Version)

Black soil represents a high-quality and scarce arable land resource, serving as a critical foundation for ensuring food security in China. However, prolonged development and utilization have resulted in varying degrees of degradation of black soil in Northeast China, directly affecting national food security and ecological stability. Since 2015, China has initiated and progressively intensified efforts in black soil protection. Technical models such as the “Lishu Model” and the “Longjiang Model” have been developed, demonstrated, and promoted, leading to increasingly significant conservation outcomes. Nevertheless, current technical models for black soil protection face dual challenges: unclear suitability boundaries and difficulties in …

Thoughts On Reform Of Fiscal S&T System Under Public Finance System, Wei Xue, Xuan Wang, Yunqiqige Wu

Bulletin of Chinese Academy of Sciences (Chinese Version)

Finance is the foundation and important pillar of national governance, a perfect financial science and technology system is of great significance for promoting scientific and technological progress, optimizing financial science and technology management, and enhancing the effectiveness of financial science and technology funds. This study discusses the main features of the financial science and technology system under the framework of public finance, summarizes the relevant reform achievements in China in recent years, identifies the main problems, clarifies the practices of innovative countries such as the United States, Germany, Britain, and Japan, and puts forward policy suggestions for further deepening the …

Construction Of Data Factor Circulation Law System In The United States And Its Reflection For China, Zihan Lin, Youmei Ma, Feng Guo

Bulletin of Chinese Academy of Sciences (Chinese Version)

As a pioneer country in the global digital economy, the United States has established a relatively complete system for the circulation of data elements. The focus is on government data openness, with the United States forming a legislative system for data openness at both federal and state levels to ensure data freedom and openness. In the field of personal data trading, the United States has established a relatively relaxed legal environment and data brokers to promote data circulation and trading. At present, China is actively promoting the market-oriented allocation reform of data elements, building a multi-level data element market, and …

Evolutionary Logic And Development Trends Of China’S Ecological And Environmental Fiscal Polocies—Quantitative Analysis Based On Policy Texts, Yu Qi, Wumei Shi, Yankun Xu

Bulletin of Chinese Academy of Sciences (Chinese Version)

The modern fiscal system has a unique role in promoting the development of green transformation, taking into account the different interests of different subjects, linking different governance links, and balancing the distribution of benefits between regions and generations, and has become a tool that is increasingly relied upon to improve the basic system of ecological civilization, sound ecological and environmental governance system, and innovate the mechanism of green and low-carbon development. Through a retrospective study of 1 516 policy texts issued by the central government departments since the reform and opening up of China, which are closely related to “ecological …

Status Quo Of Large-Scale Models, Risks And Challenges, And Recommended Countermeasures, Le Cheng, Yang Xiao

Bulletin of Chinese Academy of Sciences (Chinese Version)

Large-scale models (large models) are not only central to technological innovation, but also deeply entwined with national security, economic transformation, and social governance. This study examines the status quo of large-model development, identifies the key risks and challenges, and proposes response strategies, aiming to provide theoretical and policy insights for China’s navigations in global artificial intelligence (AI) competition and advances technological innovation. The research indicates that competition in the large-model market is fierce, while the industry is gradually consolidating. Competition in large models between China and the United States has escalated into a form of geopolitical contest. From a technical …

Comparison And Enlightenment Of International Renewable Energy Legislation Systems, Lanchun Li, Wei Feng, Wei Chen, Qing Liu

Bulletin of Chinese Academy of Sciences (Chinese Version)

The high-quality development of renewable energy cannot be achieved without legal system guarantees. In the new era, the deepening of national major strategies such as energy revolution, high-quality development, and dual carbon have put forward new and higher requirements for China’s renewable energy legal system. Based on the perspective of “past-now-future”, this study systematically reviews the development process and evolution trend of international renewable energy legal systems, extracts typical experiences of major countries, and compares and summarizes the analyses of China’s legal systems. In light of gaps, it is proposed to further improve the revision of the Renewable Energy Law …