Digital Commons Network^™

Impact Of Provision Of Abdominal Aortic Calcification Results On Fruit And Vegetable Intake: 12-Week Randomized Phase 2 Controlled Trial, Simone Radavelli-Bagatini, Catherine P. Bondonno, Jack Dalla Via, Marc Sim, Abadi K. Gebre, Lauren C. Blekkenhorst, Emma L. Connolly, Nicola P. Bondonno, John T. Schousboe, Richard J. Woodman, Kun Zhu, Shelby Mullin, Pawel Szulc, Ben Jackson, James Dimmock, Markus P. Schlaich, Kay L. Cox, Douglas P. Kiel, Wai H. Lim, Mandy Stanley, Amanda Devine, Peter L. Thompson, Evan J. Williams, Joshua R. Lewis, Moira Sim, Jonathan M. Hodgson

Research outputs 2022 to 2026

Provision of non-invasive vascular imaging results to individuals has been shown to improve cardiovascular disease risk factor control: its impact on diet remains uncertain. In this two-arm, single-blind, parallel, 12-week randomized controlled trial, 240 participants, 57.5% females aged 60–80 y had abdominal aortic calcification and clinical assessments performed at a hospital clinic. Participants were randomized 1:1 to receive (intervention n = 121) or not (control n = 119) their calcification results. Both groups received educational resources on cardiovascular disease risk control and were unblinded to the intervention. Outcome measures were performed at baseline and 12 weeks. The primary outcomes of …

The Expanding Role Of Exercise Oncology In Cancer Care: An Editorial Highlighting Emerging Research, David Mizrahi, Erika Rees-Punia, Robert U. Newton, Carolina X. Sandler

Research outputs 2022 to 2026

No abstract provided.

The Impact Of Trauma-Informed Practices On Academic Outcomes Of First Nations Children: A Pilot Study Of Culturally Responsive Supports In Australia, Govind Krishnamoorthy, Ellisa Harrison, Kay Ayre, Sayedhabibollah Ahmadi Forooshani, Emily Berger, Bronwyn Rees, Keane Wheeler, Nathan Eiby, Sabrina Ong, Vicki Dallinger, Anwaar Ulhaq

Research outputs 2022 to 2026

This pilot observational study examined the effectiveness of trauma-informed and culturally responsive behavior support practices on the academic outcomes of predominantly First Nations children in an Australian primary school. The research supports integrating culturally relevant ways of knowing, being and doing into prevalent pedagogical and behavior support practices. The cohort study found that the co-designed, multi-tier Trauma-informed Behaviour Support program improved students’ literacy and numeracy scores over 2 years. The findings highlight the complex relationship between behavioral difficulties and academic abilities. Changes in numeracy scores were significantly higher for students with improved teacher-reported rates of disruptive behaviors. In contrast, changes …

A Techno-Economic Perspective On Efficient Hybrid Renewable Energy Solutions In Douala, Cameroon’S Grid-Connected Systems, Reagan Jean Jacques Molu, Serge Raoul Dzonde Naoussi, Mohit Bajaj, Patrice Wira, Wulfran Fendzi Mbasso, Barun K. Das, Milkias Berhanu Tuka, Arvind R. Singh

Research outputs 2022 to 2026

Cameroon is currently grappling with a significant energy crisis, which is adversely affecting its economy due to cost, reliability, and availability constraints within the power infrastructure. While electrochemical storage presents a potential remedy, its implementation faces hurdles like high costs and technical limitations. Conversely, generator-based systems, although a viable alternative, bring their own set of issues such as noise pollution and demanding maintenance requirements. This paper meticulously assesses a novel hybrid energy system specifically engineered to meet the diverse energy needs of Douala, Cameroon. By employing advanced simulation techniques, especially the Hybrid Optimization Model for Electric Renewable (HOMER) Pro program, …

Higher Habitual Intakes Of Flavonoids And Flavonoid-Rich Foods Are Associated With A Lower Incidence Of Type 2 Diabetes In The Uk Biobank Cohort, Alysha S. Thompson, Amy Jennings, Nicola P. Bondonno, Anna Tresserra-Rimbau, Benjamin H. Parmenter, Claire Hill, Aurora Perez-Cornago, Tilman Kühn, Aedín Cassidy

Research outputs 2022 to 2026

Aim: To examine the associations of a diet high in flavonoid-rich foods, as reflected by a “Flavodiet Score” (FDS), the major individual food contributors to flavonoid intake, and flavonoid subclasses with type 2 diabetes (T2D) risk in the UK Biobank cohort. Materials and methods: Flavonoid intakes were estimated from ≥2 dietary assessments among 113,097 study participants [age at enrolment: 56 ± 8 years; 57% female] using the U.S Department of Agriculture (USDA) databases. Multivariable Cox proportional hazards models were used to investigate associations between dietary exposures and T2D. Results: During 12 years of follow-up, 2628 incident cases of T2D were …

Llm Potentiality And Awareness: A Position Paper From The Perspective Of Trustworthy And Responsible Ai Modeling, Iqbal H. Sarker

Research outputs 2022 to 2026

Large language models (LLMs) are an exciting breakthrough in the rapidly growing field of artificial intelligence (AI), offering unparalleled potential in a variety of application domains such as finance, business, healthcare, cybersecurity, and so on. However, concerns regarding their trustworthiness and ethical implications have become increasingly prominent as these models are considered black-box and continue to progress. This position paper explores the potentiality of LLM from diverse perspectives as well as the associated risk factors with awareness. Towards this, we highlight not only the technical challenges but also the ethical implications and societal impacts associated with LLM deployment emphasizing fairness, …

Measuring Treatment Burden In People With Type 2 Diabetes Mellitus (T2dm): A Mixed-Methods Systematic Review, Kai Lin, Mi Yao, Xinxin Ji, Rouyan Li, Lesley Andrew, Jacques Oosthuizen, Moira Sim, Yongsong Chen

Research outputs 2022 to 2026

Background: Measuring treatment burden is important for the effective management of Type 2 Diabetes Mellitus (T2DM) care. The purpose of this systematic review was to identify the most robust approach for measuring treatment burden in people with T2DM based on existing evidence. Methods: Articles from seven databases were retrieved. Qualitative, quantitative, and mixed-methods studies examining treatment burden in adults with T2DM and/or reporting relevant experiences were included. A convergent segregated approach with a mixed-methods design of systematic review was employed, creating a measurement framework in a narrative review for consistent critical appraisal. The quality of included studies was assessed using …

Metabolomic-Derived Endotypes Of Age-Related Macular Degeneration (Amd): A Step Towards Identification Of Disease Subgroups, Kevin Mendez, Ines Lains, Rachel S. Kelly, João Gil, Rufino Silva, John Miller, Demetrios G. Vavvas, Ivana Kim, Joan Miller, Liming Liang, Jessica A. Lasky-Su, Deeba Husain

Research outputs 2022 to 2026

Age-related macular degeneration (AMD) is a leading cause of blindness worldwide, with a complex pathophysiology and phenotypic diversity. Here, we apply Similarity Network Fusion (SNF) to cluster AMD patients into putative metabolomics-derived endotypes. Using a discovery cohort of 163 AMD patients from Boston, US, and a validation cohort of 214 patients from Coimbra, Portugal, we identified four distinct metabolomics-derived endotypes with varying retinal structural and functional characteristics, confirmed across both cohorts. Patients clustered into Endotype 1 exhibited a milder form of AMD and were characterized by low levels of amino acids in specific metabolic pathways. Meanwhile, patients clustered into both …

Patient Experiences: A Qualitative Systematic Review Of Chemotherapy Adherence, Amineh Rashidi, Susma Thapa, Wasana Sandamali Kahawaththa Palliya Guruge, Shubhpreet Kaur

Research outputs 2022 to 2026

Adherence to chemotherapy treatment is recognized as a crucial health concern, especially in managing cancer patients. Chemotherapy presents challenges for patients, as it can lead to potential side effects that may adversely affect their mobility and overall function. Patients may sometimes neglect to communicate these side effects to health professionals, which can impact treatment management and leave their unresolved needs unaddressed. However, there is limited understanding of how patients’ experiences contribute to improving adherence to chemotherapy treatment and the provision of appropriate support. Therefore, gaining insights into patients’ experiences is crucial for enhancing the accompaniment and support provided during chemotherapy. …

The Impact Of Armed Conflicts On Hiv Treatment Outcomes In Sub-Saharan Africa: A Systematic Review And Meta-Analysis, Hafte Kahsay Kebede, Hailay Abrha Gesesew, Amanuel Tesfay Gebremedhin, Paul Ward

Research outputs 2022 to 2026

Background: Despite the fact that Sub-Saharan Africa bears a disproportionate burden of armed conflicts and HIV infection, there has been inadequate synthesis of the impact of armed conflict on HIV treatment outcomes. We summarized the available evidence on the impact of armed conflicts on HIV treatment outcomes in Sub-Saharan Africa from 2002 to 2022. Methods: We searched four databases; MEDLINE, PubMed, CINHAL, and Scopus. We also explored grey literature sources and reviewed the bibliographies of all articles to identify any additional relevant studies. We included quantitative studies published in English from January 1, 2002 to December 30, 2022 that reported …

The Impact Of Elder Abuse Training On Subacute Health Providers And Older Adults: Study Protocol For A Randomized Control Trial, Marina G. Cavuoto, Simona Markusevska, Catriona Stevens, Patricia Reyes, Gianna Renshaw, Micah D.J. Peters, Briony Dow, Peter Feldman, Andrew Gilbert, Elizabeth Manias, Duncan Mortimer, Joanne Enticott, Claudia Cooper, Josefine Antoniades, Brenda Appleton, Sigrid Nakrem, Meghan O’Brien, Joan Ostaszkiewicz, Marion Eckert, Cheryl Durston, Bianca Brijnath

Research outputs 2022 to 2026

Background: Elder abuse often goes unreported and undetected. Older people may be ashamed, fearful, or otherwise reticent to disclose abuse, and many health providers are not confident in asking about it. In the No More Shame study, we will evaluate a co-designed, multi-component intervention that aims to improve health providers’ recognition, response, and referral of elder abuse. Methods: This is a single-blinded, pragmatic, cluster randomised controlled trial. Ten subacute hospital sites (i.e. clusters) across Australia will be allocated 1:1, stratified by state to a multi-component intervention comprising a training programme for health providers, implementation of a screening tool and use …

Understanding The Impact Of Urban Heat Islands On Crime: Insights From Temperature, Population Density, And Green Canopy Cover, Emil E. Jonescu, Chamil Erik Ramanayaka, Oluwole A. Olatunji, Talia J. Uylaki

Research outputs 2022 to 2026

Emergent literature suggests that micro- and macro-climates influence criminal behaviour; a complex phenomenon that is still incipient in theory development. This mixed-method research starts with a systematic review of the literature on the theoretical premises that urban heat islands amplify aggressive behaviour and crime. Further, it discusses the potential implications of the relationship between the environment and social outcomes on the design and planning of urban environments. A meta-synthesis was conducted to explain the correlations between patterns of criminal behaviour and thermal (dis)comfort. This correlation is to relate fundamental urban design principles to socially sustainable communities that dissuade violence and …

Associations Of Metabolic Changes And Polygenic Risk Scores With Cardiovascular Outcomes And All-Cause Mortality Across Bmi Categories: A Prospective Cohort Study, Cancan Li, Xiaoni Meng, Jie Zhang, Haotian Wang, Huimin Lu, Meiling Cao, Shengzhi Sun, Youxin Wang

Research outputs 2022 to 2026

Background: Associations between metabolic status and metabolic changes with the risk of cardiovascular outcomes have been reported. However, the role of genetic susceptibility underlying these associations remains unexplored. We aimed to examine how metabolic status, metabolic transitions, and genetic susceptibility collectively impact cardiovascular outcomes and all-cause mortality across diverse body mass index (BMI) categories. Methods: In our analysis of the UK Biobank, we included a total of 481,576 participants (mean age: 56.55; male: 45.9%) at baseline. Metabolically healthy (MH) status was defined by the presence of < 3 abnormal components (waist circumstance, blood pressure, blood glucose, triglycerides, and high-density lipoprotein cholesterol). Normal weight, overweight, and obesity were defined as 18.5 ≤ BMI < 25 kg/m2, 25 ≤ BMI < 30 kg/m2, and BMI ≥ 30 kg/m2, respectively. Genetic predisposition was estimated using the polygenic risk score (PRS). Cox regressions were performed to evaluate the associations of metabolic status, metabolic transitions, and PRS with cardiovascular outcomes and all-cause mortality across BMI categories. Results: During a median follow-up of 14.38 years, 31,883 (7.3%) all-cause deaths, 8133 (1.8%) cardiovascular disease (CVD) deaths, and 67,260 (14.8%) CVD cases were documented. Among those with a high PRS, individuals classified as metabolically healthy overweight had the lowest risk of all-cause mortality (hazard ratios [HR] 0.70; 95% confidence interval [CI] 0.65, 0.76) and CVD mortality (HR 0.57; 95% CI 0.50, 0.64) compared to those who were metabolically unhealthy obesity, with the beneficial associations appearing to be greater in the moderate and low PRS groups. Individuals who were metabolically healthy normal weight had the lowest risk of CVD morbidity (HR 0.54; 95% CI 0.51, 0.57). Furthermore, the inverse associations of metabolic status and PRS with cardiovascular outcomes and all-cause mortality across BMI categories were more pronounced among individuals younger than 65 years (Pinteraction < 0.05). Additionally, the combined protective effects of metabolic transitions and PRS on these outcomes among BMI categories were observed. Conclusions: MH status and a low PRS are associated with a lower risk of adverse cardiovascular outcomes and all-cause mortality across all BMI categories. This protective effect is particularly pronounced in individuals younger than 65 years. Further research is required to confirm these findings in diverse populations and to investigate the underlying mechanisms involved. Graphical abstract: (Figure presented.)

Barriers And Enablers To Promoting Grandchildren’S Physical Activity And Reducing Screen Time: A Qualitative Study With Australian Grandparents, Timothy Budden, David Coall, Ben Jackson, Hayley Christian, Andrea Nathan, Michelle I. Jongenelis

Research outputs 2022 to 2026

Background: With an increasing number of grandparents providing care to their grandchildren, calls have been made for these caregivers to be considered important stakeholders in encouraging children’s engagement in health-promoting behaviors, such as physical activity. Understanding the perspectives of grandparents who provide care is crucial to informing efforts that aim to increase children’s physical activity, yet little is understood about their perceptions of specific barriers and enablers to promoting children’s physical activity and reducing screen time. The present study sought to explore these perceptions. Methods: Semi-structured focus groups and individual interviews were conducted with grandparents who reported providing care to …

Dual-Trajectory Of Tyg Levels And Lifestyle Scores And Their Associations With Ischemic Stroke In A Non-Diabetic Population: A Cohort Study, Hui Zhou, Xiong Ding, Yulong Lan, Wei Fang, Xiaojie Yuan, Yan Tian, Shuohua Chen, Shouling Wu, Dan Wu

Research outputs 2022 to 2026

Background: The Triglyceride-glucose (TyG) index, a surrogate marker of insulin resistance, has been implicated in the risk of ischemic stroke. However, the interplay between TyG levels, lifestyle factors, and their collective impact on stroke risk in non-diabetic populations remains inadequately explored. This study aims to evaluate the association of ischemic stroke with the joint development of the TyG index and lifestyle in the non-diabetic population. Methods: In this prospective cohort study, data was collected across three consecutive biennial surveys of the Kailuan Study from 2006 to 2011. The dual-trajectory model was used to determine the temporal development of TyG levels …

The Effects Of Short-Term, Progressive Exercise Training On Disease Activity In Smouldering Multiple Myeloma And Monoclonal Gammopathy Of Undetermined Significance: A Single-Arm Pilot Study, A. Emery, S. Moore, J. Crowe, J. Murray, O. Peacock, D. Thompson, F. Betts, S. Rapps, L. Ross, D. Rothschild-Rodriguez, A. A. Echarri, R. Davies, R. Lewis, D. X. Augustine, A. Whiteway, Z. Afzal, J. L. J. Heaney, M. T. Drayson, J. E. Turner, John P. Campbell

Research outputs 2022 to 2026

Background: High levels of physical activity are associated with reduced risk of the blood cancer multiple myeloma (MM). MM is preceded by the asymptomatic stages of monoclonal gammopathy of undetermined significance (MGUS) and smouldering multiple myeloma (SMM) which are clinically managed by watchful waiting. A case study (N = 1) of a former elite athlete aged 44 years previously indicated that a multi-modal exercise programme reversed SMM disease activity. To build from this prior case study, the present pilot study firstly examined if short-term exercise training was feasible and safe for a group of MGUS and SMM patients, and secondly …

Association Between Inflammatory Bowel Disease And Cancer Risk: Evidence Triangulation From Genetic Correlation, Mendelian Randomization, And Colocalization Analyses Across East Asian And European Populations, Di Liu, Meiling Cao, Haotian Wang, Weijie Cao, Chenguang Zheng, Yun Li, Youxin Wang

Research outputs 2022 to 2026

Background: Inflammatory bowel disease (IBD), which includes Crohn’s disease (CD) and ulcerative colitis (UC), has been associated with several cancer risks in observational studies, but the observed associations have been inconsistent and may face the bias of confounding and reverse causality. The potential causal relationships between IBD and the risk of cancers remain largely unclear. Methods: We performed genome-wide linkage disequilibrium score regression (LDSC), standard two-sample Mendelian randomization (MR), and colocalization analyses using summary genome-wide association study (GWAS) data across East Asian and European populations to evaluate the causal relationships between IBD and cancers. Sensitivity analyses for the MR approach …

Emotional And Behavioural Difficulties Among Children And Adolescents Attending “Art Teen Clubs” In Mzuzu City In Northern Malawi: A Cross-Sectional Study, Paul U. Kaseka, Maggie Zgambo, Balwani C. Mbakaya, Mathews Lazarus, Obed Nkhata, Fatch W. Kalembo

Research outputs 2022 to 2026

Background: While triple anti-retroviral therapy (ART) has improved HIV-infected children surviving into adolescence and adulthood, these children remain vulnerable to HIV-related psychological disturbance due to both the direct HIV infection effects on the brain and indirect effects related to coping with a range of medical, psychological and social stresses associated with HIV, which makes it vital to identify their mental health needs. This study assessed the emotional and behavioural challenges of HIV perinatally infected children and adolescents with a completed disclosure process attending “ART teen club” in Malawi. Methods: A cross-sectional descriptive study design was conducted to obtain quantitative descriptive …

Measurement Of Cumulative High-Sensitivity C-Reactive Protein And Monocyte To High-Density Lipoprotein Ratio In The Risk Prediction Of Type 2 Diabetes: A Prospective Cohort Study, Dan Wu, Genyuan Chen, Yulong Lan, Shuohua Chen, Xiong Ding, Chiju Wei, Lois Balmer, Wei Wang, Shouling Wu, Wencan Xu

Research outputs 2022 to 2026

Background: Converging data have suggested that monocytic inflammation and C-reactive protein (CRP) are biologically intertwined processes and are involved in diabetogenesis. This study aimed to investigate the association between systemic inflammation assessed by joint cumulative high-sensitivity C-reactive protein (CumCRP) and monocyte to high-density lipoprotein ratio (CumMHR) and incident type 2 diabetes (T2D) and their predictive value for T2D in a general population.

Methods: A total of 40,813 nondiabetic participants from a prospective real-life cohort (Kailuan Study, China) were followed biennially from 2010/2011 until December 31, 2020. Multivariable Cox regression analyses were conducted to evaluate the adjusted hazard ratios (aHRs) of …

Cohort Profile: The Origins Pregnancy And Birth Cohort, Jacqueline Davis, Zenobia Talati, Sarah Whalan, Wesley Billingham, Nina D'Vaz, Lisa Gibson, Susan L. Prescott, Desiree T. Silva

Research outputs 2022 to 2026

No abstract provided.

Differences In Igg Afucosylation Between Groups With And Without Carotid Atherosclerosis, Cuihong Tian, Xingang Li, Hongxia Zhang, Jieyi He, Yan Zhou, Manshu Song, Peixuan Yang, Xuerui Tan

Research outputs 2022 to 2026

Background: A previous study demonstrated that N-glycosylation profiles of IgG are associated with subclinical atherosclerosis in a British population. However, the generalisability of this finding to other ethnic groups remains to be investigated, and it has yet to account for additional traditional atherosclerotic risk factors. The present study, thus, aims to explore IgG N-glycosylation profiles in Han Chinese with atherosclerosis, and their potential role in atherosclerosis, while controlling for traditional atherosclerotic risk factors. Methods: Data of this case-control study were obtained from an established umbrella Health Examination Cohort Study (registration number: ChiCTR2100048740). The investigation was conducted at the Health Care …

Downhill Running Does Not Alter Blood C1q Availability Or Complement-Dependent Cytotoxicity Of Therapeutic Monoclonal Antibodies Against Haematological Cancer Cell Lines In Vitro, Harrison D. Collier-Bain, Frankie F. Brown, Adam J. Causer, Lois Ross, Daniela Rothschild-Rodriguez, Noah Browne, Rachel Eddy, Kirstie L. Cleary, Juliet C. Gray, Mark S. Cragg, Sally Moore, James Murray, James E. Turner, John P. Campbell

Research outputs 2022 to 2026

Complement-dependent cytotoxicity (CDC) is a primary mechanism-of-action of monoclonal antibody (mAb) immunotherapies used to treat haematological cancers, including rituximab and daratumumab. However, mAb efficacy may be limited by reduced bioavailability of complement C1q – which activates the complement classical pathway following interactions with mAb-opsonised target cells. C1q is secreted by phagocytes upon recruitment to sites of muscle damage to facilitate muscular repair, hence we hypothesised that muscle damaging exercise may increase C1q ‘spill-over’ into blood. Additionally, other complement proteins (e.g., C1s) have been reported to increase following ultra-endurance and resistance exercise. Taken together, we hypothesised that muscle damaging exercise could …

Forward And Backward Private Searchable Encryption For Cloud-Assisted Industrial Iot, Tianqi Peng, Bei Gong, Shanshan Tu, Abdallah Namoun, Sami Alshmrany, Muhammad Waqas, Hisham Alasmary, Sheng Chen

Research outputs 2022 to 2026

In the cloud-assisted industrial Internet of Things (IIoT), since the cloud server is not always trusted, the leakage of data privacy becomes a critical problem. Dynamic symmetric searchable encryption (DSSE) allows for the secure retrieval of outsourced data stored on cloud servers while ensuring data privacy. Forward privacy and backward privacy are necessary security requirements for DSSE. However, most existing schemes either trade the server’s large storage overhead for forward privacy or trade efficiency/overhead for weak backward privacy. These schemes cannot fully meet the security requirements of cloud-assisted IIoT systems. We propose a fast and firmly secure SSE scheme called …

Genomic Insights Into Key Mechanisms For Carbon, Nitrogen, And Phosphate Assimilation By The Acidophilic, Halotolerant Genus Acidihalobacter Members, Himel Nahreen Khaleque, Homayoun Fathollahzadeh, Anna H. Kaksonen, Jorge Valdés, Eva Vergara, David S. Holmes, Elizabeth L.J. Watkin

Research outputs 2022 to 2026

In-depth comparative genomic analysis was conducted to predict carbon, nitrogen, and phosphate assimilation pathways in the halotolerant, acidophilic genus Acidihalobacter. The study primarily aimed to understand how the metabolic capabilities of each species can determine their roles and effects on the microbial ecology of their unique saline and acidic environments, as well as in their potential application to saline water bioleaching systems. All four genomes encoded the genes for the complete tricarboxylic acid cycle, including 2-oxoglutarate dehydrogenase, a key enzyme absent in obligate chemolithotrophic acidophiles. Genes for a unique carboxysome shell protein, csoS1D, typically found in halotolerant bacteria but not …

Immersive Virtual Reality Aggression And Violence Management Education For Nursing Students: A Pre-Test, Post-Test, Follow-Up Evaluation, Joshua Johnson, Sara Hansen, Luke Hopper, Jessica Watson, Sean Cashman, Wyatt De Souza, Brennen Mills

Research outputs 2022 to 2026

Background: Nursing students attending clinical placement encounter similar exposure to aggression and violence as qualified clinicians. Universities encounter barriers in aggression and violence management education delivery due to resourcing and time requirements. Immersive Virtual Reality (IVR) education may reduce barriers while maintaining comparable learning outcomes to face-to-face simulation-based education. Method: Nursing students (n = 72), recruited from one public university in Perth, Western Australia, completed a 15-20 minute IVR education program. Pre-, post-, and 4-month post-intervention questionnaires investigated self-reported confidence. Cross-sectional data were collected for system usability and motion sickness. Results: Significant differences in self-reported confidence were observed (p < .001, partial η2 = 0.53), with large improvements from pre- to post-intervention (p < .001, d = 1.21) and follow-up (p < .001, d = 1.25). Cross-sectional data indicated the program is easy to use and incurs negligible motion sickness. Conclusion: IVR can deliver effective aggression and violence education for nursing students. The short duration, high usability, and persistence of confidence improvements over time indicate potential for IVR to support current nursing education practices.

Impact Of Healthy Pregnancy And Lifestyle In Mothers On Developmental Delay In Their Offspring: A Strength-Based Analysis Of A Longitudinal Study Among Indigenous Children In Australia, Md Irteja Islam, Thomas Stubbs, Tuguy Esgin, Alexandra Martiniuk

Research outputs 2022 to 2026

Introduction: Extensive literature has investigated the prenatal risk factors of developmental delay in children, with evidence highlighting the impact of prenatal health, mental health, and behavioural factors. While a deficit discourse has underscored Indigenous health research and policies, strengths-based approaches provide an opportunity to reframe this discourse, to illustrate and celebrate the strength and resilience of Australian Indigenous families. As such, this study aimed to identify the protective impact of healthy pregnancy and lifestyle in mothers on developmental delay in Indigenous Australian children; and whether it varies by child birthweight adjusted for gestational age. Further, we also tested whether child …

Planning And Evaluating An Integrated Clinical Exercise Oncology Service: An Exploratory Mixed-Methods Study, Ciaran M. Fairman, Shana E. Harrington, Alec R. Schumpp, Alex M. Brooks, Morgan J. Jones, Julian Kim, Mary A. Kennedy

Research outputs 2022 to 2026

Background: This project aimed to design and evaluate the potential to integrate an exercise oncology service into clinical care in a local healthcare system. The goal was to inform the design of an implementation strategy to promote its sustainable use in standard care. Methods: This two-phase, exploratory study used a mixed-methods approach. First, qualitative measures were used to understand the context for exercise integration into oncology care by clinicians and administrators in the healthcare system. Next, the Reach, Effectiveness, Adoption, Implementation, Maintenance (RE-AIM) framework guided a comprehensive evaluation of the exercise service. Reach and Adoption were measured via number of …

Global Patterns And Drivers Of Fish Reproductive Potential On Coral Reefs, Jeneen Hadj-Hammou, Joshua E. Cinner, Diego R. Barneche, Iain R. Caldwell, David Mouillot, James P.W. Robinson, Nina M.D. Schiettekatte, Alexandre C. Siqueira, Brett M. Taylor, Nicholas A.J. Graham

Research outputs 2022 to 2026

Fish fecundity scales hyperallometrically with body mass, meaning larger females produce disproportionately more eggs than smaller ones. We explore this relationship beyond the species-level to estimate the “reproductive potential” of 1633 coral reef sites distributed globally. We find that, at the site-level, reproductive potential scales hyperallometrically with assemblage biomass, but with a smaller median exponent than at the species-level. Across all families, modelled reproductive potential is greater in fully protected sites versus fished sites. This difference is most pronounced for the important fisheries family, Serranidae. When comparing a scenario where 30% of sites are randomly fully protected to a current …

Identifying Payable Cluster Distributions For Improved Reservoir Characterization: A Robust Unsupervised Ml Strategy For Rock Typing Of Depositional Facies In Heterogeneous Rocks, Umar Ashraf, Aqsa Anees, Hucai Zhang, Muhammad Ali, Hung Vo Thanh, Yujie Yuan

Research outputs 2022 to 2026

The oil and gas industry relies on accurately predicting profitable clusters in subsurface formations for geophysical reservoir analysis. It is challenging to predict payable clusters in complicated geological settings like the Lower Indus Basin, Pakistan. In complex, high-dimensional heterogeneous geological settings, traditional statistical methods seldom provide correct results. Therefore, this paper introduces a robust unsupervised AI strategy designed to identify and classify profitable zones using self-organizing maps (SOM) and K-means clustering techniques. Results of SOM and K-means clustering provided the reservoir potentials of six depositional facies types (MBSD, DCSD, MBSMD, SSiCL, SMDFM, MBSh) based on cluster distributions. The depositional facies …

It’S About Time: Mitigating Cancer-Related Cognitive Impairments Through Findings From Computational Models Of The Wisconsin Card Sorting Task, Darren Haywood, Frank D. Baughman, Evan Dauer, Jennifer Haywood, Susan Rossell, Nicolas H. Hart

Research outputs 2022 to 2026

Background: Many cancer survivors experience cancer-related cognitive impairment (CRCI), often with significant negative consequences across various life domains. Emerging evidence suggests that allowing additional time to process information before acting may be a useful strategy for those with CRCI to mitigate some of its impacts. The Wisconsin Card Sorting Task (WCST), a measure of general cognition, has shown that for some cancer survivors, longer task completion time facilitates similar task performance outcomes to control populations concerning perseveration errors; a key performance metric of the WCST. However, assessing if this strategy may be useful, as well as determining for whom it …