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Us Or Them: How Covid-19 Vaccine Priority Influences Perceptions Of Local-Migrant Worker Relations, Tengjiao Huang, Haochen Zhou, Liz Jones, Chin Wen Cong Dec 2024

Us Or Them: How Covid-19 Vaccine Priority Influences Perceptions Of Local-Migrant Worker Relations, Tengjiao Huang, Haochen Zhou, Liz Jones, Chin Wen Cong

Research Collection School of Social Sciences

The COVID-19 pandemic laid bare pre-existing societal fault lines, placing immense strain on intergroup relations and giving rise to xenophobic sentiments. Drawing on Realistic Conflict Theory (RCT) and Social Identity Approach (SIA), our study examined how the public allocation of COVID-19 variant vaccines could influence the dynamics between local citizens and migrant workers, and under what conditions. One key idea is that valued resource distribution that favour migrant workers may produce increased perceptions of realistic threats among local citizens which could lead to exacerbated negative attitudes and behaviours of high-status local citizens towards low-status migrants, whereas higher fairness perceptions of …


Longitudinal Bidirectional Relation Between Fear Of Missing Out And Risky Loot Box Consumption: Evidence For Fomo-Driven Loot Boxes Spiral Hypothesis, Andree Hartanto, K Tennakoon Appuhamillage Sandeeshwara Kasturiratna Dec 2024

Longitudinal Bidirectional Relation Between Fear Of Missing Out And Risky Loot Box Consumption: Evidence For Fomo-Driven Loot Boxes Spiral Hypothesis, Andree Hartanto, K Tennakoon Appuhamillage Sandeeshwara Kasturiratna

Research Collection School of Social Sciences

Background: The integration of loot boxes has emerged as a significant factor contributing to the increasing revenue in the video gaming industry. However, this integration has also led to widespread engagement in risky loot box consumption. To understand the mechanism that drives and sustains such maladaptive behavior, we propose the FoMO-Driven Loot Boxes Spiral Hypothesis – positing that fear of missing out (FoMO) not only triggers initial engagement in risky loot box consumption but also perpetuates a self-reinforcing cycle, where such engagement intensifies subsequent FoMO, leading to further risky loot box consumption. Method and results: We conducted a 13-week longitudinal …


Positive And Negative Affect Differentially Predict Individual Differences And Intra-Individual Changes In Daily Cognitive Failures In Younger And Older Adults, Ysabel A. Guevarra, Nadyanna M. Majeed, Nur Eva Alisha Binte Mohamed Hisham, Andree Hartanto Dec 2024

Positive And Negative Affect Differentially Predict Individual Differences And Intra-Individual Changes In Daily Cognitive Failures In Younger And Older Adults, Ysabel A. Guevarra, Nadyanna M. Majeed, Nur Eva Alisha Binte Mohamed Hisham, Andree Hartanto

Research Collection School of Social Sciences

(1) Background: Cognitive failures, including lapses in attention, memory, and executive functioning, can negatively affect daily performance and well-being. Negative and positive affectivity have been implicated in cognitive functioning, yet their relationship with cognitive failures remains underexplored. This study investigates the impact of positive and negative affect on cognitive failures, using daily diary methods to examine both within-person and between-person associations in a sample of younger adults from Singapore and adults across the lifespan from the United States (US). (2) Methods: Participants (Singapore: N = 253, US: N = 1726) completed daily diaries over seven (Singapore) or eight (US) consecutive …


Advances In Research On Anthropogenic Drivers Of Climate Change, Andrew Jorgenson, Hassan El Tinay, Jared Fitzgerald, Jennifer Givens, Taekyeong Goh, Xiaorui Huang, Orla Kelly, Annika Marie Rieger, Ryan P. Thombs Dec 2024

Advances In Research On Anthropogenic Drivers Of Climate Change, Andrew Jorgenson, Hassan El Tinay, Jared Fitzgerald, Jennifer Givens, Taekyeong Goh, Xiaorui Huang, Orla Kelly, Annika Marie Rieger, Ryan P. Thombs

Research Collection School of Social Sciences

This chapter provides an overview of advances in social science research on the anthropogenic drivers of climate change. Anthropogenic drivers refer to the social systems and human actions causing GHG emissions, and societal factors shaping and conditioning those actions. The authors summarize the contemporary drivers research literature on (1) economic growth, (2) income and wealth inequality, (3) environmental load displacement and ecologically unequal exchange, (4) militarization, and (5) corporations. In addition to summarizing recent work, the authors identify future directions for each of these areas of research, as well as ways in which they can be better integrated.


(In)Visible China: Understanding Chinese Global Orders, Hassan Karrar, William A. Callahan, Carwyn Morris, Stephen Whiteman Dec 2024

(In)Visible China: Understanding Chinese Global Orders, Hassan Karrar, William A. Callahan, Carwyn Morris, Stephen Whiteman

Research Collection School of Social Sciences

Where is China going? What does its alternative global order look like? We hear a lot about China’s grand projects like the Belt and Road Initiative, but how are they experienced on the ground in Africa, South America, and Asia?The Chinese Global Orders project brings together twenty-two scholars from five continents to explore these questions. As these four commentaries show, it seeks to pluralize the discussion by exploring “Chinese” beyond the PRC nation-state, “Global” as a space beyond the international, and “Orders” as a plural set of norms.The project seeks to do more than just describe Global China’s material impact, …


The Effects Of Casein Glycomacropeptide On General Health Status In Children With Pku: A Randomized Crossover Trial, Alex Pinto, Anne Daly, Camille Newby, Abigail Robotham, Simon Heales, Simon Eaton, Helen Aitkenhead, Kimberly Gilmour, Richard Jackson, Catherine Ashmore, Sharon Evans, Júlio Cesar Rocha, Fatma Ilgaz, Mary Hickson, Anita Macdonald Dec 2024

The Effects Of Casein Glycomacropeptide On General Health Status In Children With Pku: A Randomized Crossover Trial, Alex Pinto, Anne Daly, Camille Newby, Abigail Robotham, Simon Heales, Simon Eaton, Helen Aitkenhead, Kimberly Gilmour, Richard Jackson, Catherine Ashmore, Sharon Evans, Júlio Cesar Rocha, Fatma Ilgaz, Mary Hickson, Anita Macdonald

School of Health Professions

In PKU, it is suggested that casein glycomacropeptide based protein substitute (GMP) may have physiological advantage when satiety, oxidative stress, renal function and inflammation are considered. Its prebiotic properties may also help gastrointestinal (GI) tolerance. In children with PKU, a randomized/crossover trial comparing phenylalanine-free amino acids (AA) vs GMP as the single source of protein substitute for 12-weeks in each arm was conducted. There was a 4-week wash out period with AA in-between. At baseline and end of each intervention, blood and fecal samples were taken to monitor gut health, oxidative stress, renal function, inflammatory markers and plasma amino acids. …


The Scale Question As An Urban Question: The Making Of Homo Urbanicus Amid State Entrepreneurialism, Yong Zhang Dec 2024

The Scale Question As An Urban Question: The Making Of Homo Urbanicus Amid State Entrepreneurialism, Yong Zhang

Research Collection College of Integrative Studies

This research bridges two influential strands of literature on urban China—state entrepreneurialism and homo urbanicus (城市人). By revisiting how China’s post-reform urban transformation has unfolded and connecting it to current development strategies, this research provides a fresh perspective on the country’s urbanization processes and their implications for future governance. The analysis proposes an alternative periodization of three phases: anti-migration urbanism, anti-settlement urbanism, and anti-civitas urbanism. Beyond understanding urbanization as a crisis-driven, state-rescaling phenomenon pivoting around the blending of state and market forces, this research repositions the concept of homo urbanicus, or the urban citizen, as central to understanding the urban …


Uncovering Electric Vehicle Ownership Disparities Using K-Means Clustering Analysis: A Case Study Of Austin, Texas, Seung Jun Choi, Junfeng Jiao Dec 2024

Uncovering Electric Vehicle Ownership Disparities Using K-Means Clustering Analysis: A Case Study Of Austin, Texas, Seung Jun Choi, Junfeng Jiao

Research Collection College of Integrative Studies

Transportation electrification is promoted for its environmental and energy efficiency benefits. However, recent studies examining electric vehicle (EV) adoption have revealed complex patterns influenced by race and income disparities. These studies, primarily based on surveys, often overlook regional ownership variations and built environment measures linked to urban form. Our study addresses this gap by analyzing actual EV registration data with spatial details using hot spot and K-means clustering analyses. The analysis results revealed a pronounced East–West divide in EV adoption. In West Austin, clusters indicate a higher number of EVs, greater energy consumption, and residents who are predominantly White, with …


Korean Epistemology And Research: Centering Local Epistemologies In Qualitative Inquiry, Seungho Moon Dec 2024

Korean Epistemology And Research: Centering Local Epistemologies In Qualitative Inquiry, Seungho Moon

Education: School of Education Faculty Publications and Other Works

This study examines how philosophical questions and discussions surrounding Korean epistemology can be reconstructed and created through qualitative research. Drawing upon Korea’s unique perspectives on human relationships and worldviews, it explores diverse discourses on knowledge and truth. Through a case-study approach, the author investigates the potential for qualitative researchers of varying cultural and historical heritage to expand their horizons and directions of qualitative inquiry. Illuminating the ontological dynamics of being and non-being within the multifaceted and in-depth discourses of Korean epistemology, it offers an example of what new versions of qualitative research are possible based on methodologies such as Suda, …


The Rage, Fall 2024, Aspen Humphries, Savannah Moore, Lottie Taylor Dec 2024

The Rage, Fall 2024, Aspen Humphries, Savannah Moore, Lottie Taylor

The Rage Zine

The Rage zine is published in collaboration with Students Advocating Gender Equality and CCU Women's and Gender Studies. Volume 3, Issue 1.


Neurocognitive Functioning Of Patients With Sinonasal And Nasopharyngeal Cancers Treated With Multimodality Therapy, Dan Yaniv, Lindsay M Niccolai, Jeffrey S Wefel, Catherine M Sullaway, Jack Phan, Clifton David Fuller, Kareem B Haroun, Ehab Y Hanna, Shirley Y Su Dec 2024

Neurocognitive Functioning Of Patients With Sinonasal And Nasopharyngeal Cancers Treated With Multimodality Therapy, Dan Yaniv, Lindsay M Niccolai, Jeffrey S Wefel, Catherine M Sullaway, Jack Phan, Clifton David Fuller, Kareem B Haroun, Ehab Y Hanna, Shirley Y Su

Faculty, Staff and Student Publications

Importance Few recent studies have examined neurocognitive functioning (NCF) in patients with sinonasal and nasopharyngeal cancers (NPCs) prior to and following multimodality therapy or the potential differences in NCF by disease variables such as disease site.

Objective The objective of this study is to determine rates of NCF impairments prior to and following multimodality therapy, declines in NCF following radiotherapy (RT), and possible differences in NCF by the disease site.

Design, Setting, and Participants We conducted a retrospective chart review of 39 patients with sinonasal and NPCs who underwent comprehensive neuropsychological evaluations. Twenty patients were evaluated prior to RT, of …


Adjuvant Rituximab And Elevated Intratumoural Cd8 Expression Are Associated With Sustained Disease Control After Radiotherapy In A Randomised Trial Of Systemic Therapy In Early-Stage Follicular Lymphoma, Michael P Macmanus, John F Seymour, Hennes Tsang, Richard Fisher, Colm Keane, Muhammed B Sabdia, Soi C Law, Jay Gunawardana, Karthik Nath, Stephen H Kazakoff, Mario L Marques-Piubelli, Daniela E Duenas, Michael R Green, Daniel Roos, Peter O'Brien, Andrew Mccann, Richard Tsang, Sidney Davis, David Christie, Chan Cheah, Benhur Amanuel, Tara Cochrane, Jason Butler, Anna Johnston, Mohamed Shanavas, Li Li, Claire Vajdic, Robert Kridel, Victoria Shelton, Samantha Hershenfield, Tara Baetz, David Lebrun, Nathalie Johnson, Marianne Brodtkorb, Maja Ludvigsen, Francesco D'Amore, Ella R Thompson, Piers Blombery, Maher K Gandhi, Joshua W D Tobin Dec 2024

Adjuvant Rituximab And Elevated Intratumoural Cd8 Expression Are Associated With Sustained Disease Control After Radiotherapy In A Randomised Trial Of Systemic Therapy In Early-Stage Follicular Lymphoma, Michael P Macmanus, John F Seymour, Hennes Tsang, Richard Fisher, Colm Keane, Muhammed B Sabdia, Soi C Law, Jay Gunawardana, Karthik Nath, Stephen H Kazakoff, Mario L Marques-Piubelli, Daniela E Duenas, Michael R Green, Daniel Roos, Peter O'Brien, Andrew Mccann, Richard Tsang, Sidney Davis, David Christie, Chan Cheah, Benhur Amanuel, Tara Cochrane, Jason Butler, Anna Johnston, Mohamed Shanavas, Li Li, Claire Vajdic, Robert Kridel, Victoria Shelton, Samantha Hershenfield, Tara Baetz, David Lebrun, Nathalie Johnson, Marianne Brodtkorb, Maja Ludvigsen, Francesco D'Amore, Ella R Thompson, Piers Blombery, Maher K Gandhi, Joshua W D Tobin

Faculty, Staff and Student Publications

Background: We report extended follow-up of TROG99.03, a randomised phase III trial in early-stage follicular lymphoma (ESFL) including new information on the role of adjuvant rituximab and translational studies.

Methods: Patients with ESFL were randomised to involved field radiotherapy (IFRT) or IFRT plus 6-cycles cyclophosphamide/vincristine/prednisolone (IFRT + CVP). From 2006 rituximab was added to IFRT + CVP (IFRT + R-CVP). Clinical and multi-omic parameters were evaluated. Findings were validated in two independent ESFL cohorts (99 and 60 patients respectively).

Findings: Between 2000 and 2012, 150 (75 per arm) patients were recruited. 48% were positron emission tomography (PET)-staged. By protocol, at …


Reconstructing Modernism: How Literary Experimentation Created Outlets For Faulkner And Toomer To Reinterpret The American South’S History, Jack Cattie Dec 2024

Reconstructing Modernism: How Literary Experimentation Created Outlets For Faulkner And Toomer To Reinterpret The American South’S History, Jack Cattie

Undergraduate Theses and Capstone Projects

An era of literary and artistic experimentation known as Modernism began in the 1920s allowing authors to reinterpret history and society. American Modernist authors William Faulkner and Jean Toomer used a variety of innovative literary techniques to depict post-Civil War Reconstruction (1864-1877) and its aftermath. Faulkner’s Absalom, Absalom! and Toomer’s Cane examine themes of race, violence, and the Lost Cause by manipulating time and perspective, shifting genres, and introducing new sentence structures. This article situates these novels alongside contemporary historical monographs and articles including works by Eric Foner, Deborah Gray White, Joe William Trotter Jr., and David Blight to demonstrate …


Engineering Immunity: Bacterial Delivery Of Cancer Neoantigen Vaccines, Christopher D Johnston, Jennifer A Wargo Dec 2024

Engineering Immunity: Bacterial Delivery Of Cancer Neoantigen Vaccines, Christopher D Johnston, Jennifer A Wargo

Faculty, Staff and Student Publications

In the battle against cancer, researchers are exploring the use of engineered bacteria as living medicines. Redenti and colleagues demonstrate that Escherichia coli Nissle 1917 (EcN) can be engineered to deliver cancer neoantigen payloads, stimulating antigen-specific CD4+ and CD8+ T cells and mediating antitumor immunity in preclinical models of colorectal cancer and melanoma.


Prevalence, Diagnostic Features, And Medical Outcomes Of Females With Turner Syndrome With A Trisomy X Cell Line (45, X/47, Xxx): Results From The Insights Registry, Natalia Klamut, Samantha Bothwell, Alexandra E Carl, Vaneeta Bamba, Jennifer R Law, Wendy J Brickman, Karen O Klein, Roopa Kanakatti Shankar, Catherina T Pinnaro, Patricia Y Fechner, Siddharth K Prakash, Iris Gutmark-Little, Susan Howell, Nicole Tartaglia, Marybel Good, Kelly C Ranallo, Shanlee M Davis Dec 2024

Prevalence, Diagnostic Features, And Medical Outcomes Of Females With Turner Syndrome With A Trisomy X Cell Line (45, X/47, Xxx): Results From The Insights Registry, Natalia Klamut, Samantha Bothwell, Alexandra E Carl, Vaneeta Bamba, Jennifer R Law, Wendy J Brickman, Karen O Klein, Roopa Kanakatti Shankar, Catherina T Pinnaro, Patricia Y Fechner, Siddharth K Prakash, Iris Gutmark-Little, Susan Howell, Nicole Tartaglia, Marybel Good, Kelly C Ranallo, Shanlee M Davis

Faculty, Staff and Student Publications

Turner syndrome (TS) is defined by partial or complete absence of a sex chromosome. Little is known about the phenotype of individuals with TS mosaic with trisomy X (45,X/47,XXX or 45,X/46,XX/47,XXX) (~3% of TS). We compared the diagnostic, perinatal, medical, and neurodevelopmental comorbidities of mosaic 45,X/47,XXX (n = 35, 9.4%) with nonmosaic 45,X (n = 142) and mosaic 45,X/46,XX (n = 66). Females with 45,X/47,XXX had fewer neonatal concerns and lower prevalence of several TS-related diagnoses compared with 45,X; however the prevalence of neurodevelopmental and psychiatric diagnoses were not different. Compared to females with 45,X/46,XX, the 45,X/47,XXX group was significantly …


Digital Scholarship Lab Summer 2024 Survey Report, Sean Winslow Dec 2024

Digital Scholarship Lab Summer 2024 Survey Report, Sean Winslow

Reports and White Papers - Milner Library

During the Summer of 2024, the Digital Scholarship Lab at Milner Library conducted a survey to garner feedback on user interests and needs to help guide the work of the new Digital Scholarship Coordinator, Dr. Sean Winslow, who joined the library in April. The Digital Scholarship Lab opened in August 2023, but many potential users did not know it existed or the specifics of its infrastructure as it relates to their needs.


The Prognostic Impact Of Tumor Deposits In Colorectal Cancer: More Than Just N1c, Neal Bhutiani, Oliver Peacock, Abhineet Uppal, Chung-Yuan Hu, Brian K Bednarski, Melissa W Taggart, Arvind Dasari, Van K Morris, Harmeet Kaur, Scott Kopetz, Emma B Holliday, Prajnan Das, Y Nancy You, George J Chang Dec 2024

The Prognostic Impact Of Tumor Deposits In Colorectal Cancer: More Than Just N1c, Neal Bhutiani, Oliver Peacock, Abhineet Uppal, Chung-Yuan Hu, Brian K Bednarski, Melissa W Taggart, Arvind Dasari, Van K Morris, Harmeet Kaur, Scott Kopetz, Emma B Holliday, Prajnan Das, Y Nancy You, George J Chang

Faculty, Staff and Student Publications

Background: The identification of tumor deposits (TD) currently plays a limited role in staging for colorectal cancer (CRC) aside from N1c lymph node designation. The objective of this study was to determine the prognostic impact, beyond American Joint Committee on Cancer N1c designation, of TDs among patients with primary CRC.

Methods: Patients who had resected stage I-III primary CRC diagnosed between 2010 and 2019 were identified from the National Cancer Institute's Surveillance, Epidemiology, and End Results database. Cancer-specific survival (CSS) stratified by TD status and lymph node (N) status was calculated using the Kaplan-Meier method and multivariable Cox proportional hazards …


Mimosa: A Resource Consisting Of Improved Methylome Prediction Models Increases Power To Identify Dna Methylation-Phenotype Associations, Hunter J Melton, Zichen Zhang, Hong-Wen Deng, Lang Wu, Chong Wu Dec 2024

Mimosa: A Resource Consisting Of Improved Methylome Prediction Models Increases Power To Identify Dna Methylation-Phenotype Associations, Hunter J Melton, Zichen Zhang, Hong-Wen Deng, Lang Wu, Chong Wu

Faculty, Staff and Student Publications

Although DNA methylation (DNAm) has been implicated in the pathogenesis of numerous complex diseases, from cancer to cardiovascular disease to autoimmune disease, the exact methylation sites that play key roles in these processes remain elusive. One strategy to identify putative causal CpG sites and enhance disease etiology understanding is to conduct methylome-wide association studies (MWASs), in which predicted DNA methylation that is associated with complex diseases can be identified. However, current MWAS models are primarily trained using the data from single studies, thereby limiting the methylation prediction accuracy and the power of subsequent association studies. Here, we introduce a new …


Sitravatinib In Patients With Solid Tumors Selected By Molecular Alterations: Results From A Phase Ib Study, Lyudmila Bazhenova, Dong-Wan Kim, Byoung Chul Cho, Sanjay Goel, Rebecca Heist, Theresa L Werner, Keith D Eaton, Judy S Wang, Shubham Pant, Douglas R Adkins, Collin M Blakely, Xiaohong Yan, Saskia Neuteboom, James G Christensen, Richard Chao, Todd Bauer Dec 2024

Sitravatinib In Patients With Solid Tumors Selected By Molecular Alterations: Results From A Phase Ib Study, Lyudmila Bazhenova, Dong-Wan Kim, Byoung Chul Cho, Sanjay Goel, Rebecca Heist, Theresa L Werner, Keith D Eaton, Judy S Wang, Shubham Pant, Douglas R Adkins, Collin M Blakely, Xiaohong Yan, Saskia Neuteboom, James G Christensen, Richard Chao, Todd Bauer

Faculty, Staff and Student Publications

No abstract provided.


Improved Robustness For Deep Learning-Based Segmentation Of Multi-Center Myocardial Perfusion Cardiovascular Mri Datasets Using Data-Adaptive Uncertainty-Guided Space-Time Analysis., Dilek M Yalcinkaya, Khalid Youssef, Bobak Heydari, Janet Wei, C Noel Bairey Merz, Robert Judd, Rohan Dharmakumar, Orlando P Simonetti, Jonathan W Weinsaft, Subha V Raman, Behzad Sharif Dec 2024

Improved Robustness For Deep Learning-Based Segmentation Of Multi-Center Myocardial Perfusion Cardiovascular Mri Datasets Using Data-Adaptive Uncertainty-Guided Space-Time Analysis., Dilek M Yalcinkaya, Khalid Youssef, Bobak Heydari, Janet Wei, C Noel Bairey Merz, Robert Judd, Rohan Dharmakumar, Orlando P Simonetti, Jonathan W Weinsaft, Subha V Raman, Behzad Sharif

Heart and Vascular Articles

BACKGROUND: Fully automatic analysis of myocardial perfusion cardiovascular magnetic resonance imaging datasets enables rapid and objective reporting of stress/rest studies in patients with suspected ischemic heart disease. Developing deep learning techniques that can analyze multi-center datasets despite limited training data and variations in software (pulse sequence) and hardware (scanner vendor) is an ongoing challenge.

METHODS: Datasets from three medical centers acquired at 3T (n = 150 subjects; 21,150 first-pass images) were included: an internal dataset (inD; n = 95) and two external datasets (exDs; n = 55) used for evaluating the robustness of the trained deep neural network (DNN) models …


Off-Protocol Radiation Therapy In Phase 3 Metastatic Solid Tumor Trials, Alexander D Sherry, Timothy A Lin, Zachary R Mccaw, Esther J Beck, Ramez Kouzy, Joseph Abi Jaoude, Adina H Passy, Avital M Miller, Gabrielle S Kupferman, Clifton David Fuller, Charles R Thomas, Eugene J Koay, Chad Tang, Pavlos Msaouel, Ethan B Ludmir Dec 2024

Off-Protocol Radiation Therapy In Phase 3 Metastatic Solid Tumor Trials, Alexander D Sherry, Timothy A Lin, Zachary R Mccaw, Esther J Beck, Ramez Kouzy, Joseph Abi Jaoude, Adina H Passy, Avital M Miller, Gabrielle S Kupferman, Clifton David Fuller, Charles R Thomas, Eugene J Koay, Chad Tang, Pavlos Msaouel, Ethan B Ludmir

Faculty, Staff and Student Publications

Purpose: Increasing data suggest that radiation therapy, particularly ablative radiation therapy, alters the natural history of metastatic disease. For patients with metastatic disease enrolled in prospective trials testing systemic therapy, the use of off-protocol radiation therapy to improve clinical symptoms or extend the duration of study systemic therapy may influence study endpoints. We sought to evaluate how often off-protocol radiation therapy was permitted among systemic therapy phase 3 trials, how often off-protocol radiation therapy is used, and whether off-protocol radiation therapy correlated with study outcomes.

Methods and materials: Two-arm, superiority-design, phase 3 randomized trials testing systemic therapy were screened from …


Contemporary Approach To The Diagnosis And Classification Of Myelodysplastic Neoplasms/Syndromes-Recommendations From The International Consortium For Myelodysplastic Neoplasms/Syndromes (Mds [Icmds]), Fnu Aakash, Savanah D Gisriel, Amer M Zeidan, John M Bennett, Rafael Bejar, Jan Philipp Bewersdorf, Uma M Borate, Jacqueline Boultwood, Andrew M Brunner, Rena Buckstein, Hetty E Carraway, Jane E Churpek, Naval G Daver, Amy E Dezern, Fabio Efficace, Pierre Fenaux, Maria E Figueroa, Guillermo Garcia-Manero, Steven D Gore, Peter L Greenberg, Elizabeth A Griffiths, Stephanie Halene, Christopher S Hourigan, Tae Kon Kim, Nina Kim, Rami S Komrokji, Vijay K Kutchroo, Alan F List, Richard F Little, Ravindra Majeti, Aziz Nazha, Stephen D Nimer, Olatoyosi Odenike, Eric Padron, Mrinal M Patnaik, Uwe Platzbecker, Matteo G Della Porta, Gail J Roboz, David A Sallman, Valeria Santini, Guillermo Sanz, Michael R Savona, Mikkael A Sekeres, Maximilian Stahl, Daniel T Starczynowski, David P Steensma, Justin Taylor, Omar Abdel-Wahab, Andrew H Wei, Zhuoer Xie, Mina L Xu, Robert P Hasserjian, Sanam Loghavi Dec 2024

Contemporary Approach To The Diagnosis And Classification Of Myelodysplastic Neoplasms/Syndromes-Recommendations From The International Consortium For Myelodysplastic Neoplasms/Syndromes (Mds [Icmds]), Fnu Aakash, Savanah D Gisriel, Amer M Zeidan, John M Bennett, Rafael Bejar, Jan Philipp Bewersdorf, Uma M Borate, Jacqueline Boultwood, Andrew M Brunner, Rena Buckstein, Hetty E Carraway, Jane E Churpek, Naval G Daver, Amy E Dezern, Fabio Efficace, Pierre Fenaux, Maria E Figueroa, Guillermo Garcia-Manero, Steven D Gore, Peter L Greenberg, Elizabeth A Griffiths, Stephanie Halene, Christopher S Hourigan, Tae Kon Kim, Nina Kim, Rami S Komrokji, Vijay K Kutchroo, Alan F List, Richard F Little, Ravindra Majeti, Aziz Nazha, Stephen D Nimer, Olatoyosi Odenike, Eric Padron, Mrinal M Patnaik, Uwe Platzbecker, Matteo G Della Porta, Gail J Roboz, David A Sallman, Valeria Santini, Guillermo Sanz, Michael R Savona, Mikkael A Sekeres, Maximilian Stahl, Daniel T Starczynowski, David P Steensma, Justin Taylor, Omar Abdel-Wahab, Andrew H Wei, Zhuoer Xie, Mina L Xu, Robert P Hasserjian, Sanam Loghavi

Faculty, Staff and Student Publications

Myelodysplastic neoplasms/syndromes (MDS) are a heterogeneous group of biologically distinct entities characterized by variable degrees of ineffective hematopoiesis. Recently, 2 classification systems (the 5th edition of the World Health Organization Classification of Haematolymphoid tTumours and the International Consensus Classification) further subcharacterized MDS into morphologically and genetically defined groups. Accurate diagnosis and subclassification of MDS require a multistep systemic approach. The International Consortium for MDS (icMDS) summarizes a contemporary, practical, and multimodal approach to MDS diagnosis and classification.


Gravity- Vs Wall Suction-Driven Large-Volume Thoracentesis: A Randomized Controlled Study, Samira Shojaee, Jasleen Pannu, Lonny Yarmus, Alberto Fantin, Christina Macrosty, Roland Bassett, Labib Debiane, Zachary S Depew, Saadia A Faiz, Carlos A Jimenez, Sameer K Avasarala, Erik Vakil, Andrew Demaio, Lara Bashoura, Keerthana Keshava, Travis Ferguson, Roberto Adachi, George A Eapen, David E Ost, Sami Bashour, Asad Khan, Vickie Shannon, Ajay Sheshadri, Roberto F Casal, Scott E Evans, Krystle Pew, Nadia Castaldo, Diwakar D Balachandran, Vincenzo Patruno, Robert Lentz, Cheryl Pai, Fabien Maldonado, Lance Roller, Junsheng Ma, Jhankruti Zaveri, Jenna Los, Luis Vaquero, Eva Ordonez, Gulmira Yermakhanova, Jason Akulian, Cole Burks, Roel-Rolando Almario, Marie Sauve, Jackson Pettee, Laila Z Noor, Muhammad H Arain, Horiana B Grosu Dec 2024

Gravity- Vs Wall Suction-Driven Large-Volume Thoracentesis: A Randomized Controlled Study, Samira Shojaee, Jasleen Pannu, Lonny Yarmus, Alberto Fantin, Christina Macrosty, Roland Bassett, Labib Debiane, Zachary S Depew, Saadia A Faiz, Carlos A Jimenez, Sameer K Avasarala, Erik Vakil, Andrew Demaio, Lara Bashoura, Keerthana Keshava, Travis Ferguson, Roberto Adachi, George A Eapen, David E Ost, Sami Bashour, Asad Khan, Vickie Shannon, Ajay Sheshadri, Roberto F Casal, Scott E Evans, Krystle Pew, Nadia Castaldo, Diwakar D Balachandran, Vincenzo Patruno, Robert Lentz, Cheryl Pai, Fabien Maldonado, Lance Roller, Junsheng Ma, Jhankruti Zaveri, Jenna Los, Luis Vaquero, Eva Ordonez, Gulmira Yermakhanova, Jason Akulian, Cole Burks, Roel-Rolando Almario, Marie Sauve, Jackson Pettee, Laila Z Noor, Muhammad H Arain, Horiana B Grosu

Faculty, Staff and Student Publications

Background: Prior studies have found no differences in procedural chest discomfort for patients undergoing manual syringe aspiration or drainage with gravity after thoracentesis. However, whether gravity drainage could protect against chest pain due to the larger negative-pressure gradient generated by wall suction has not been investigated.

Research question: Does wall suction drainage result in more chest discomfort compared with gravity drainage in patients undergoing large-volume thoracentesis?

Study design and methods: In this multicenter, single-blinded, randomized controlled trial, patients with large free-flowing effusions of ≥ 500 mL were assigned at a 1:1 ratio to wall suction or gravity drainage. Wall suction …


Body Composition In Recurrent Prostate Cancer And The Role Of Steroidogenic Genotype, Neha Venkatesh, Rebecca S Tidwell, Yao Yu, Ana Aparicio, Amado J Zurita, Sumit K Subudhi, Bilal A Siddiqui, Sagar S Mukhida, Justin R Gregg, Paul G Corn, Efstratios Koutroumpakis, Jennifer L Mcquade, Daniel E Frigo, Patrick G Pilie, Chad Huff, Christopher J Logothetis, Andrew W Hahn Dec 2024

Body Composition In Recurrent Prostate Cancer And The Role Of Steroidogenic Genotype, Neha Venkatesh, Rebecca S Tidwell, Yao Yu, Ana Aparicio, Amado J Zurita, Sumit K Subudhi, Bilal A Siddiqui, Sagar S Mukhida, Justin R Gregg, Paul G Corn, Efstratios Koutroumpakis, Jennifer L Mcquade, Daniel E Frigo, Patrick G Pilie, Chad Huff, Christopher J Logothetis, Andrew W Hahn

Faculty, Staff and Student Publications

Hormone therapy (HT) to treat prostate cancer is reported to cause adverse changes in body composition. Clinically, interpatient body composition changes are heterogeneous, but the biological and clinical determinants of body composition toxicity are unknown. Herein, we test the hypothesis that inherited polymorphisms in steroidogenic genes are associated with differential changes in body composition after HT. Men with biochemically recurrent prostate cancer (BCR) who received 8 months of LHRH analog (LHRHa) +/- abiraterone acetate (AAP) were eligible if they had: i) CT imaging of L3 prior to and after treatment; and ii) nucleated cells collected. Cardiometabolic co-morbidities were retrospectively extracted. …


Old Becoming New Again: A Form-Function And Narrative Analysis Of Ralph Vaughan Williams’ 'Fantasia On A Theme Of Thomas Tallis', Aileen E. Sager Dec 2024

Old Becoming New Again: A Form-Function And Narrative Analysis Of Ralph Vaughan Williams’ 'Fantasia On A Theme Of Thomas Tallis', Aileen E. Sager

Electronic Theses and Dissertations

Ralph Vaughan Williams, a leading figure in the early twentieth-century movement to preserve traditional English music, composed Fantasia on a Theme of Thomas Tallis as a tribute to his love of Tudor music and English folksong. The piece is based on a psalm setting by Thomas Tallis, known as the Third Mode Melody, which features the Phrygian mode. Vaughan Williams discovered this theme while researching for the new English Hymnal. A brief history of the Tallis theme, along with an exploration of Vaughan Williams' education and early endeavors as a composer, are critical to understanding the Fantasia's historical …


The Relationship Between Salvinia Molesta Infestation And The Microbial Ecology Of Wetlands At Caddo Lake, Tx, Usa, Martin Hadsell Dec 2024

The Relationship Between Salvinia Molesta Infestation And The Microbial Ecology Of Wetlands At Caddo Lake, Tx, Usa, Martin Hadsell

Electronic Theses and Dissertations

Wetlands are known to host many beneficial geochemical processes such as nutrient cycling and carbon sequestration. These processes are primarily driven by the microbial communities within a wetland. The establishment of non-native invasive species within wetlands has the potential to alter the once beneficial functionality of wetland microbial communities due to the sensitivity microbes have towards environmental changes. Because of this, several metagenomic studies have been conducted to assess microbial community response to aquatic plant invasion; however, there haven’t been any studies researching the influence of Salvinia molesta (D.S. Mitch.), commonly known as Giant Salvinia, on microbial communities. The goal …


Soundscapes Of The Pillow Book: Creating Music Exploring Pamela Z'S Sonic Landscapes, Asuka Kakitani Dec 2024

Soundscapes Of The Pillow Book: Creating Music Exploring Pamela Z'S Sonic Landscapes, Asuka Kakitani

Electronic Theses and Dissertations

Pamela Z stands as a pioneering force in contemporary music, seamlessly integrating her roles as a composer, performer, and media artist. Renowned for her innovative approach, she masterfully combines her voice with live electronic processing, sampled sounds, and video elements, crafting a distinctive musical landscape that embodies the forefront of artistic exploration in our time. The primary aim of this thesis is to create “The Pillow Book,” a new musical work inspired by Z's creative process and methods. This work will also incorporate elements of my native language and ancient Japanese text from The Pillow Book, written in 1002 …


Sing A New Song: Analyzing A Cappella Arrangements Of Contemporary Worship Music, Ashley S. Cox Dec 2024

Sing A New Song: Analyzing A Cappella Arrangements Of Contemporary Worship Music, Ashley S. Cox

Electronic Theses and Dissertations

Music is indispensable to Christian worship services, and pop/rock-influenced contemporary worship music (CWM) serves an important role in modern worship. This thesis explores strategies for arranging CWM for a cappella settings by comparing the originals with two a cappella arrangements: one intended for group performance and the other for congregational worship. This will be accomplished through examining the following five songs: “Hymn of Heaven,” “Raise a Hallelujah,” “Build Your Kingdom Here,” “Psalm 34 (Taste and See),” and “Battle Belongs.” Analysis of elements such as form, texture, harmony, and rhythm reveals many arranging techniques. The songs are categorized by the level …


Bioremediation Of Effluent Water In A Coal Ash Disposal Area: Optimizing Microbial Sulfate Reduction, Ryka Shea Dec 2024

Bioremediation Of Effluent Water In A Coal Ash Disposal Area: Optimizing Microbial Sulfate Reduction, Ryka Shea

Electronic Theses and Dissertations

Coal combustion residues (CCR) pose a serious environmental threat, even long after they are disposed of in specialized landfills, due to their complex composition and potential for leaching into waterways. This study focuses on the issue of elevated sulfate concentrations at the Martin Lake Steam Electric Station (MLSES) A-I Disposal Area in Panola County, Texas, where CCR are disposed of in a permanent landfill. Currently, this site is exceeding its regulatory limit of sulfate concentrations in its effluent and is in need of a cost-effective and sustainable solution to this problem. This research utilized benchtop experiments to investigate sulfate reducing …


Mortality Risks Associated With Depression In Men With Prostate Cancer, Casey Crump, Pär Stattin, James D Brooks, Jan Sundquist, Weiva Sieh, Kristina Sundquist Dec 2024

Mortality Risks Associated With Depression In Men With Prostate Cancer, Casey Crump, Pär Stattin, James D Brooks, Jan Sundquist, Weiva Sieh, Kristina Sundquist

Faculty, Staff and Student Publications

Background: Men diagnosed with prostate cancer (PC) have an increased risk of depression; however, it is unclear to what extent depression affects long-term survival. A better understanding of such effects is needed to improve long-term care and outcomes for men with PC.

Objective: To determine the associations between major depression and mortality in a national cohort of men with PC.

Design, setting, and participants: A national cohort study was conducted of all 180 189 men diagnosed with PC in Sweden during 1998-2017. Subsequent diagnoses of major depression were ascertained from nationwide outpatient and inpatient records through 2018.

Outcome measurements and …