Digital Commons Network^™

Perceptions Of Civilian Faculty In Professional Military Education Regarding Graduate Students’ Development Of Writing Skills, Katherine Zimmerle

Walden Dissertations and Doctoral Studies

The problem that was investigated through this study was the gap in literature about civilian faculty’s perceptions of the writing skills needed and how best to support student success in graduate-level professional military education (PME) university programs. Grounded in schema theory and transfer theory, the purpose of this basic qualitative study was to investigate the perceptions of PME civilian faculty regarding the writing skills needed and recommendations thereof to strengthen the writing skill support in PME university programs. Data were collected through semistructured interviews with eight PME civilian faculty members with at least 3 years of experience. Qualitative content analysis …

Regulating Manipulative Design Is Not Preempted By Cda 230 Or The First Amendment, Brett Frischmann, Peter Ormerod

Faculty Publications

For over two decades, there has been a heated debate among legal scholars, activists, judges, and others about the scope of Section 230 of the Communications Decency Act. A persistent theme in those debates has been hyperbolic claims about the necessity of immunity from state laws for digital tech platforms and fearmongering that anything less than maximum immunity will destroy the Internet.

This Article argues that states retain considerable discretion to regulate digital platforms’ design and engineering decisions. We argue that manipulation, engineered behavior, and even habituation and normalization of engineered behavior by digital platforms are content-agnostic harms attributable to …

Lats1/2-Cd38 Metabolic Rewiring Links Senescence To Intraplaque Thrombosis, Sivareddy Kotla, Jonghae Lee, Kyung Ae Ko, Weiqing Chen, Venkata Subrahmanya Kumar Samanthapudi, Oanh Hoang, Gilbert F Mejia, Shengyu Li, Hani Lee, Aijun Zhang, Min Soon Cho, Keri L Schadler, Luis Antonio Rivera, Masaki Imanishi, Kay Carlene Tavares Samperio, Jung Hyun Kim, Kelia C Ostos-Mendoza, Karla N Mariscal-Reyes, Anita Deswal, John P Cooke, Keigi Fujiwara, Nicolas L Palaskas, Efstratios Koutroumpakis, Young Jin Gi, Rajneesh Pathania, Craig Morrell, Philip L Lorenzi, Lin Tan, Iqbal Mahmud, Nordin M J Hanssen, Vahid Afshar-Kharghan, Dale J Hamilton, Laurent Yvan-Charvet, Eduardo N Chini, Joerg Herrmann, Hernan G Vasquez, Ying H Shen, James F Martin, Haodong Xu, Erin H Seeley, Jared K Burks, Paul S Brookes, Guangyu Wang, Nhat-Tu Le, Jun-Ichi Abe

Faculty, Staff and Students Publications

Background: Atherothrombosis, which underlies most acute coronary syndromes and is driven by intraplaque thrombosis, preferentially occurs in regions of disturbed blood flow (d-flow). Although LATS1/2 (large tumor suppressor kinases 1 and 2) are known regulators of endothelial mechanotransduction, the mechanisms by which d-flow connects endothelial senescence, proliferation, and intraplaque thrombosis remain poorly understood.

Methods: We investigated endothelial cell (EC)-specific roles of Lats1/2 using inducible EC-specific knockout mice in a partial carotid ligation model. Spatial multiomics of human and mouse plaques was performed using imaging mass cytometry, COMET sequential immunofluorescence, and spatial metabolomics.

Results: Tamoxifen-induced deletion of both Lats1 and Lats2 …

Single-Nucleotide Rna M6a Mapping In Bovine Preimplantation Development Reveals Site-Specific Regulation Of Rpl12 At Zygotic Genome Activation, Hao Ming, Kinga Pajdzik, Noah R Rakestraw, Piyush K Jain, Chuan He, Chenghang Zong, Zongliang Jiang

Faculty, Staff and Students Publications

RNA N6-methyladenosine (m6A) is a key regulator of gene expression during early embryogenesis. Using SAC-seq (m6A-selective allyl chemical labeling and sequencing), an antibody-independent m6A profiling method, we generated the first single-nucleotide-resolution m6A map of bovine oocytes and preimplantation embryos. We observed both coordinated and uncoupled relationships between m6A modification and expression of protein-coding and noncoding genes. Integrative analysis of the transcriptome, m6A epitranscriptome, and translatome revealed dynamic m6A remodeling, particularly in ribosomal protein genes. Functional interrogation of a specific m6A site within the RPL12 transcript demonstrated that loss of this modification reduces protein synthesis, disrupts translation-related gene expression, impairs zygotic …

Subunit Composition Of The Katp Channels That Modulate Contractility Of Skeletal Muscle During Fatigue, Rosa Scala, Yuezhou Chen, Berk Mizrak, Gretchen A Meyer, Colin G Nichols

2020-Current year OA Pubs

ATP-sensitive potassium (KATP) channels are among the most expressed ion channels in skeletal muscle sarcolemma. While all KATP subunits can be detected in skeletal muscles, transcripts are enriched for KCNJ11 and ABCC9, suggesting that noncanonical Kir6.2/SUR2A assembly may constitute the majority of sarcolemmal KATP channels, but there has been no systematic dissection of KATP makeup in skeletal muscles. Here, we used a unique collection of murine lines selectively lacking specific channel-forming subunits (knockout, KO), and combined a genetic and pharmacological approach to determine which subunits of KATP channels are functionally relevant for skeletal muscle contraction. Under fatiguing conditions, isometric tetanic …

Long-Term Inactivation Mediated By Different Fgf-A Homologues On Heterologously Expressed Nav1.2 Currents, Yenisleidy Lorenzo-Ceballos, Pedro L Martinez-Espinosa, Xiao-Ming Xia, Christopher J Lingle

2020-Current year OA Pubs

A-isoforms of cytosolic growth factor homologous factors (FGF11-14) mediate long-term inactivation (LTI) of voltage-dependent sodium (NaV) channels. LTI is a rapid onset process that is competitive with the fast inactivation (IF) intrinsic to NaV channels, with little or no interconversion between inactivated states. Since recovery from LTI is orders of magnitude slower than recovery from IF, repetitive depolarizations lead to use-dependent accumulation of NaV channels in slow recovery states, thereby limiting NaV availability during trains of action potentials. Of the two or more N-terminal splice variants of the various FGF homologues, LTI specifically arises only from the A-isoform of each …

The Asymmetric Effect Of The Rupiah Exchange Rate On Indonesia's Non-Oil And Gas Exports, Muhammad Sugiantoro, Diah Wahyuningsih, Ris Yuwono Yudo Nugroho, Widita Kurniasari, Ahmad Kamil

Jurnal Ekonomi dan Studi Pembangunan

This study aims to analyze the asymmetric effect of the rupiah exchange rate on Indonesia's non-oil and gas sector exports, by considering the control variables. As well as identifying whether Indonesia's non-oil and gas sector exports are more responsively influenced by rupiah exchange rate depreciation or rupiah exchange rate appreciation. The analysis technique used is Nonlinear Autoregressive Distributed Lag (NARDL) with quarterly data from 2016 to 2023. The results showed that the rupiah exchange rate has an asymmetric effect on Indonesia's non-oil and gas sector exports, both in the short and long term. Depreciation and appreciation of the rupiah exchange …

A Process For The Preparation Of Methyl {4,6-Diamino-2-[5-Fluoro-1-(2-Fluorobenzyl)-1h-Pyrazolo[3,4-B] Pyridin-3-Yl] Pyrimidin-5-Yl} Carbamate, And Its Intermediates, Tummuru Srinivas Reddy

Defensive Publications Series

The present invention relates to 5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b] pyridine-3-carboximidamide hydrate, is represented by following structural formula (5) and its process for the preparation thereof.

The present invention also relates to crystalline form of 5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b] pyridine-3-carboximidamide hydrate of Formula (5) and its process for the preparation thereof.

The present invention further relates to use of 5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b] pyridine-3-carboximidamide hydrate of Formula (5) for the preparation of Methyl {4,6-diamino-2-[5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b] pyridin-3-yl] pyrimidin-5-yl} carbamate, is represented by following structural formula (1).

Adaptive Multi-Format Prompt Preprocessing Using Unified Reinforcement Learning Framework, Katyayani Kiranmayee Kolluru, Shivam Mohan

Defensive Publications Series

The present disclosure provides a system for adaptive multi-format prompt preprocessing using a unified reinforcement learning framework. The system includes a prompt-type classifier (116) configured to identify a format type of an input prompt, wherein the format type includes one of natural language text, code, log, hybrid content, or error trace, the prompt-type classifier (116) being configured in some embodiments to perform deterministic rule-based classification. The system further includes a feature extraction layer (118) configured to produce a multi-modal representation of the input prompt capturing structural, linguistic, and semantic signals. The system also includes a hierarchical reinforcement learning policy engine …

Emotionally Coherent Procedural World Generation: Environmental Psychology As A Generative Framework For Automated 3d World Construction, Michael D. Conduit

Defensive Publications Series

This disclosure describes a method and system for procedurally generating three-dimensional virtual environments whose spatial composition, asset placement, and atmospheric properties are driven by parameters derived from empirical environmental psychology research. The core innovation is the use of multi-dimensional emotional profile vectors — parameterised from validated human perception studies including prospect-refuge theory, vastness-awe research, and spatial density psychology — as the primary control surface for an automated world generation pipeline.

Unlike prior approaches that use aesthetic heuristics, noise-based randomness, or manual artist direction, the system described here encodes psychological research findings directly as generative constraints. The result is environments in …

In-File Stapled Freshness: Hash-Chain Validity Tokens Written Into A Frozen Self-Serialized Document Via A Length-Preserving Neutralized Zone, With Fail-Stale Offline Verification, Michael Benaudis

Defensive Publications Series

Revocation of frozen offline credentials — single-file HTML documents, PDFs, or other self-serialized digital credentials verified without any network, server, or public-key infrastructure — is information-theoretically constrained: a file sealed at issuance cannot learn of a later revocation event unless some information reaches the verification context. This disclosure does not remove that channel; it reduces it to one short, public, unforgeable hash-chain token per validity period, relayable by any untrusted party, and relocates the freshness proof inside the credential file itself. At issuance, a hash-chain tip (Micali NOVOMODO style) and period parameters are embedded in the credential's signed core, attested …

Canonical Multi-Zone Neutralization For Self-Serialized Documents Carrying Heterogeneous Hybrid Signatures, A Self-Referential Integrity Digest, And A Post-Signing Timestamp Anchor, Michael Benaudis

Defensive Publications Series

A self-serialized digital document — a single HTML file, PDF, or archive — sometimes must embed, within its own byte stream, three mutually dependent cryptographic elements: a hybrid digital signature combining a classical algorithm (ECDSA P-256) with a post-quantum algorithm (ML-DSA-65, FIPS 204); a self-referential SHA-256 integrity digest computed over the document's own serialization; and a blockchain timestamp anchor reference (Bitcoin, Ethereum) whose value becomes known only after the document has been hashed and submitted for anchoring. Embedding all three inside one serialized body creates a circular dependency that naive ordering cannot resolve: signatures must cover content that sits next …

Proportional Transmit Power Allocation Based On Channel Quality In Multi‑Antenna Systems, Sangwook Suh, Scott Huang, Ayrton Chen, Guosen Yue, Han Kim, Taeyoon Kim, Cp Chiang, Peng Wu, Insoo Hwang

Defensive Publications Series

In cellular networks, a user equipment device utilizing multiple transmit antennas might experience high block error rates when a gain imbalance exists between transmission paths. To handle multi-antenna transmissions, conventional approaches might allocate an equal amount of transmission power across available antennas. However, this equal allocation might expend energy on attenuated channels, lowering an overall signal-to-noise ratio at a receiving station.

A method is disclosed that assigns transmit power proportionally based on an evaluated channel quality for each antenna path. The method evaluates a reference signal received power for individual paths and directs a larger portion of transmission power to …

Persistent Driver Signatures For Software-Defined Vehicles, Sean C. Keys, Karsten Knese

Defensive Publications Series

This disclosure describes a system that enables software-defined vehicles (SDVs), smart cars, or connected autonomous vehicles to adjust their advanced driver assistance systems (ADAS) based on a persistent driver signature. The driver signature acts as a portable digital identity or user profile representing a driver’s unique physiological and behavioral tendencies, such as typical steering and braking patterns. Instead of storing raw data like video files, the system relies on a cloud database to store a secure mathematical model (a vector or tensor) that represents these individual habits. At the beginning of each trip, the SDV identifies the driver using a …

Automated Context-Aware In-Video Advertising Through Multimodal Generative Models, Lakshmi Venkatesh Kakumani

Defensive Publications Series

The disclosed technology employs an automated pipeline to dynamically insert context-aware digital advertisements into video streams. A vision-language model (VLM) processes decoded video frames to perform spatiotemporal affordance and obstacle detection, identifying semantic regions suitable for ad placement. If an existing object obstructs the placement area, a physics-aware preparation layer performs 3D semantic object translation. This object translation directly  morphs an existing unbranded scene object into a branded alternative while preserving the original scene physics and lighting. The system generates a joint multimodal embedding vector representing the immediate semantic and audio context of the video. This vector guides an image …

Process For The Preparation Of Intermediates Of Resmetirom, Msn Laboratories Private Limited, R&D Center; Srinivasan Thirumalai Rajan; Revu Satyanarayana And Siddireddygari Maheshwar Reddy.

Defensive Publications Series

The present disclosure relates to an process for the preparation of synthetic intermediates in the manufacture of Resmetirom (MGL-3196), a selective thyroid hormone receptor-β (THR-β) agonist approved for the treatment of non-cirrhotic non-alcoholic steatohepatitis (NASH) with moderate-to-advanced liver fibrosis.

Ct-Derived Epicardial Adipose Tissue Density And Its Association With Systemic Inflammation And Functional Impairment In Heart Failure With Preserved Ejection Fraction: A Prospective Cross-Sectional Study From Oman, Arif Albulushi, Ahmed Tawfek, Ahmed Basuoni

Journal of the Saudi Heart Association

Background: Heart failure with preserved ejection fraction (HFpEF) is strongly influenced by cardiometabolic comorbidity and systemic inflammation. Epicardial adipose tissue (EAT) is a biologically active visceral fat depot in direct contact with the myocardium, and CT-derived EAT density (attenuation) may reflect inflammatory adipose remodeling beyond adipose quantity alone. However, the clinical relevance of EAT density in HFpEF remains uncertain.

Objectives: To evaluate the association of CT-derived EAT density with systemic inflammatory biomarkers, functional capacity, health status, and echocardiographic indices of HFpEF severity in a prospective cross-sectional cohort.

Methods: In a prospective cross-sectional study conducted between January and July 2024 at …

The Music Of The Spheres In The Western Imagination (2022), By David J. Kendall, Brad Eden

Journal of Tolkien Research

Book review, by Bradford Lee Eden, of The Music of the Spheres in the Western Imagination (2022), by David J. Kendall

Dnp Final Report: Impact Of Education For Public School Caregivers On Reducing Complications In Type 1 Diabetes, Jena Decanter

DNP Final Reports

Abstract Background: Children with Type 1 diabetes (T1D) rely on school personnel to recognize symptoms and respond to diabetes-related emergencies during the school day. However, many rural school districts lack standardized training for staff responsible for supporting students with chronic health conditions. Purpose: This quality improvement project evaluated the feasibility and educational impact of a brief, self-paced, evidence-based diabetes education program designed to improve school personnel knowledge and response confidence related to T1D management. Methods: A quality improvement design was used in which school personnel with direct student contact completed an asynchronous educational module. Outcome measures included the Michigan Diabetes …

A Brief Summary Of Albert Camus’S “The Myth Of Sisyphus”, Irma Mosqueda Perez

Philosophy - All Scholarship

In the first pages of The Myth of Sisyphus, Albert Camus chooses to discuss beliefs and values, before diving deep into his theory on absurdism. His purpose is to set the groundwork for his future ideas on the meaning or rather, the lack of meaning of life. So he begins, piece by piece assembling the big puzzle that ends in his theory of philosophical absurdism and continues with an evaluation of the central question of this book: is suicide a justified approach when facing life? In this essay I plan on doing an exposition of the main points of Camus’s …

Faithful Ole Miss Alumnus Pays It Forward, Bill Dabney

University of Mississippi News

OXFORD, Miss. – For Rob Whorton, supporting the University of Mississippi is not just about giving back; it is about paying forward opportunities that shaped his lifetime and honoring his father, who taught him the value of education.

Role Of Guidelines, Legislation, Litigation And Mechanisms For Sudep Communication In The Uk And In The Usa: A State-Of-The-Art Review, Rohit Shankar

Peninsula Medical School

IntroductionSudden unexpected death in epilepsy (SUDEP) remains a leading cause of premature mortality in people with epilepsy despite decades of research and guideline development.MethodsThis state-of-the-art narrative review synthesises multidisciplinary evidence from clinical guidelines, epidemiology, legal frameworks, policy initiatives, and advocacy sources in the United Kingdom (UK) and United States of America (USA). The review is structured to examine current practice (“where are we now”), evolution of influencing mechanisms (“how did we get here”), and future directions for improving SUDEP prevention (“where should we go next”).ResultsWhere are we now SUDEP risk communication remains inconsistent despite clear guideline recommendations. Implementation is hindered …

Consciousness And Knowledge Organization In Lis: Online And Offline Bubbles Of Experience, Arwa Alsultan

Library Philosophy and Practice (e-journal)

Knowledge organization (KO) systems such as the Dewey Decimal Classification (DDC) structure human knowledge primarily through disciplinary subject relationships, leaving the subjective, experiential dimension of knowledge engagement largely unexamined. This conceptual study extends David Gamez's (2018) distinction between "online" (environmentally-coupled) and "offline" (environmentally-decoupled) bubbles of experience into Library and Information Science (LIS), proposing that DDC's ten main classes can be interpreted as differing in the dominant mode of conscious engagement they require. Drawing on Integrated Information Theory, Global Workspace Theory, and Default Mode Network research, the study maps each DDC class onto this experiential spectrum and examines the cognitive capacities …

Dynlp: Parallel Dynamic Batch Update For Label Propagation In Graph-Based Semi-Supervised Learning, S. M. Shovan, Arindam Khanda, S. M. Ferdous, Sajal K. Das, Mahantesh Halappanavar

Computer Science Faculty Research & Creative Works

Semi-supervised learning aims to infer class labels using only a small fraction of labeled data. In graph-based semi-supervised learning, this is typically achieved through label propagation to predict labels of unlabeled nodes. However, in real-world applications, new data often arrives in batches, and stale data often becomes irrelevant. Each time a new batch appears, reapplying the traditional label propagation algorithm to recompute all labels is redundant, computationally intensive, and inefficient. To address the absence of an efficient label propagation update method, we propose DynLP, a novel GPU-centric Dynamic Batched Parallel Label Propagation algorithm that performs only the necessary updates, propagating …

Enhancing Construction Simulation Optimization Performance Through Variance Reduction Techniques, Mohammed Mawlana, Amin Hammad

College of Architecture and the Built Environment Faculty Papers

Simulation optimization has been used to analyze construction operations and support planning decisions under uncertainty. It enables the identification of effective planning strategies throughout a project’s lifecycle. However, the use of stochastic simulation to evaluate alternative strategies results in higher computational demands and the generation of inferior solutions within the resulting optimal solutions. This study examines the feasibility of overcoming these issues by implementing variance reduction techniques into a discrete-event simulation optimization framework. Three variance reduction techniques are evaluated in a case study: Common Random Numbers, Antithetic Variates, and a combined application of both. While these techniques are well established …

Barriers In Diagnosing Gender Dysphoria In Youth: A Scoping Review, Kayla Perfetto

Scoping Review Protocols

Objective: Specifically, through this review, I aim to explore the barriers influencing clinicians when diagnosing gender dysphoria in youth populations. The objective of this scoping review is to understand the extent and type of evidence in relation to this topic.

Introduction: The existing literature highlights significant uncertainty among mental health professionals in diagnosing and providing care for transgender and gender-diverse youth, posing substantial challenges for tailored support. This scoping review aims to condense the extant literature on the variables impacting clinicians’ diagnosis of gender dysphoria in children and adolescents, addressing critical gaps and providing a comprehensive resource for stakeholders.

Inclusion …

Vibro-Seismic Approach For Remediation Of Near-Wellbore Damage, Mounira Ahmed Abdallah

Theses and Dissertations

The research highlights the importance of vibro-seismic technology in the oil and gas industry. The primary objective of this study is to demonstrate how the vibro-seismic method enhances formation properties which are porosity, and permeability. Ultimately, this will lead to improved productivity and its application to remove the wellbore damage.

The research discusses whether or not the formation properties will be enhanced by the optimized acoustic vibration formation parameters. The thesis details laboratory experiments on core plugs, and four key findings are presented. The experimental work first showed that the use of the proper and optimum parameters enhanced the porosity …

Rethinking Nuclear Liability In The Age Of Small Modular Reactors, Isabella Klesmith

NULR Online

No abstract provided.

3d Semi-Analytical Thermo-Elasto-Plastic Model For Additive Manufacturing, Tao Liu, Ming C. Leu, Edward C. Kinzel, Chinedum Okwudire

Mechanical and Aerospace Engineering Faculty Research & Creative Works

In additive manufacturing (AM), stress field drives distortion and warping and promotes delamination and cracking. Fast, accurate stress prediction is therefore essential for AM process planning and control, including real-time adaptive control, AM digital twins, data-driven and physics-driven workflows. However, spot-wise thermo-elasto-plastic finite element method (FEM) are often too slow for design iteration or real time use. Existing semi-analytical thermo-elasto-plastic approaches achieve high speed but are largely limited to 2D. In this paper, a full 3D semi-analytical thermo-elasto-plastic model for AM is built. The method uses a spot-wise analytical thermal field as the load and computes displacements and stresses via …

Developmental Stability Of Task-Rest Neural Efficiency In Youth Using A Threat And Cognitive Control Task, Parmis Khosravi, Julia O. Linke, Anjali D. Poe, Chase Antonacci, Reut Naim, Elise M. Cardinale, Katharina Kircanski, Anderson M. Winkler, Nathan A. Fox, Daniel Samuel Pine, Simona P. Haller

School of Medicine Publications

Behaviors arise from coordinated neural activity across diverse spatial and temporal scales. Prior work has linked better task performance and cognitive functioning to patterns of global network connectivity requiring minimal reconfiguration when switching between task demands. This metric indexing similarity in functional connectivity across task and rest has been termed “neural efficiency.” Here we assess stability of neural efficiency over approximately 3 years in adolescence, specificity across two task-rest combinations and associations with anxiety. At approximately age 16 and/or 19, 95 participants completed a resting state scan alongside a cognitive control and/or threat task. Neural efficiency was quantified as partial …