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Pacific Rxtracts - June 2026, Pacific Rxtracts

Pacific RxTracts

Articles:

• FDA Approves First Non-Antipsychotic Drug for Patients with Alzheimer’s Disease Agitation
• FDA Approves Sparsentan for Focal Segmental Glomerulosclerosis
• Lunsotogene Rings in a New Era of Gene Therapy for Hearing Loss
• Sex Differences in Breakthrough Stroke Outcomes Despite Oral Anticoagulation for Atrial Fibrillation
• Asundexian for Secondary Prevention After Ischemic Stroke or TIA
• Marstacimab Prophylaxis in Hemophilia A/B with Inhibitors: A New Purpose
• FDA Approves First-in-Class Weekly Anifrolumab Autoinjector for Systemic Lupus Erythematosus 
• Cemdisiran in Generalized Myasthenia Gravis
• Medicare’s Impact on Early Sepsis Management and Discharge to Home
• Maralixibat Shows Broader Therapeutic Benefit for Children with Alagille Syndrome 
• Reaching the Littlest …

Sums Of Kloosterman Sums Over Square-Free And Smooth Integers, Xuancheng Shao, Igor E. Shparlinski, Laurence P. Wijaya

Mathematics Faculty Publications

Recently, there has been a large number of works on bilinear sums with Kloosterman sums and on sums of Kloosterman sums twisted by arithmetic functions. Motivated by these, we consider several related new questions about sums of Kloosterman sums parametrised by square-free and smooth integers. Some of our results are presented in the much more general setting of trace functions.

Updates To The Caniform Fauna (Carnivora, Caniformia) Of The John Day Formation, Oregon, Usa, John D. Orcutt, Kevin C. Talbott, Michael J. Monroe, Nicholas A. Famoso

Biology Faculty Scholarship

The John Day Formation of central Oregon preserves a diversity of Oligo-Miocene caniform carnivorans, many of which were first described from the formation. However, many historically important specimens lack detailed locality or stratigraphic information, complicating any analysis of faunal change through time. Here, we describe 16 new specimens of caniforms from the John Day Formation, most with precise stratigraphic information. We report multiple specimens of the amphicyonids Daphoenus Leidy, 1853, Paradaphoenus cuspigerus (Cope, 1878), and Temnocyon altigenis (Cope, 1878), all previously known from the formation. We also report the first definitive occurrence of the hesperocyonine canid Osbornodon Wang, 1994 from …

Leveraging Ict Adoption And Electricity Access For Sustainable Agricultural Productivity Among Nigerian Households, Menghan Huang, Qin Chen, Oluwayemisi Kadijat Adeleke, Mamdouh Abdulaziz Saleh Al-Faryan

The Philippine Agricultural Scientist

This study investigated ICT adoption (mobile phone and internet usage), access to electricity, and their impact on household agricultural productivity in Nigeria, Africa’s largest economy. Utilizing Wave 4 (2018 to 2019) Living Standards Measurement Study–Integrated Survey on Agriculture (LSMS–ISA) data covering 4,980 household heads, this study applied logit regression and Propensity Score Matching (PSM) for estimation, alongside a Cobb-Douglas production function to analyze input contributions to agricultural output. The findings revealed that the age, residential location, educational level, and access to electricity of household heads significantly determine technology adoption among farming households. Furthermore, ICT adoption exhibits a significant, positive relationship …

Establishing An Elite Core Panel For Accelerating Genetic Gain In The Philrice Irrigated Rice Breeding Program, Leonilo V. Gramaje, Frodie P. Waing, Raysha Ann Marie Garcia, Nia N. Manlulu, Rogemae C. Ravela, Alvin D. Palanog, Oliver E. Manangkil, Holden Verdeprado, Rose Imee Zhella Amar-Morante, Norvie L. Manigbas, Pompe C. Sta Cruz, Suresh Babu Kadaru, Parthiban Thathapalli Prakash, Jose E. Hernandez

The Philippine Agricultural Scientist

Increasing the performance of rice varieties in terms of yield and other economically significant traits through genetic improvement is crucial to achieving food security in the Philippines. The Department of Agriculture– Philippine Rice Research Institute (PhilRice) plays a central role in developing high-yielding rice varieties that are more adaptable to local conditions to meet national rice demand. This study determined the trend in genetic gain for yield among national test entries from 2015 through 2021 using historical data and evaluated key agronomic, grain quality, and pest- and disease-resistance traits as criteria for assembling an elite core panel. Historical yield data …

Effect Of Leaf Harvesting Frequency On Cassava Leaf Production And Tuber Yield Of Binulak, Lakan 1 (Upl Cv-2), And Sultan 6 (Nsic 2003 Cv-25), Fides Marciana Z. Tambalo, Rosa Buena A. Capuno, Hiyasmin Rose L. Benzon, Jayson F. Garcia, Lizette Sahar N. Arcillas, Rona Joy C. Tud

The Philippine Agricultural Scientist

Cassava (Manihot esculenta Crantz) is a vital staple crop in many developing countries, valued for its adaptability and dual-purpose use of roots and leaves. This study investigated the effects of leaf harvesting frequency on the leaf and tuber yields of 3 locally grown cassava varieties: Binulak, Lakan 1, and Sultan 6. The experiment followed a split plot in a Randomized Complete Block Design with 4 treatments varying in leaf harvesting frequency and initiation. Cassava leaves were harvested at 4, 6, 8, or 10 mo after planting (MAP), and tubers were harvested at 10 MAP. Results indicated that leaf yield …

Growth And Yield Of Rice (Oryza Sativa L.) Under Different Irrigation Methods In Transplanted And Direct-Seeded Systems, Wang Guirui, Crisanta S. Bueno

The Philippine Agricultural Scientist

In the face of climate change and socioeconomic transformation, there is an urgent need to save energy and enhance rice production. Direct-seeded rice (DSR) is a viable alternative to transplanted rice due to reduced water and labor requirements, potentially achieving comparable or higher yields with reduced inputs. This study was conducted in the 2025 dry and wet seasons in Los Baños, Philippines, using a 2-factorial randomized complete block design with 4 replications. The first factor was the 2 rice varieties NSIC Rc 506 (Tubigan 41, V1) and NSIC Rc 160 (Tubigan 14, V2), and the second factor was cultural management, …

In Vitro Assessment Of The Reproductive Biology Of Sweet Potato Weevil, Cylas Formicarius (Fabricius) (Coleoptera: Brentidae) Among Commonly Grown Sweet Potato Cultivars, Jerah Mystica Novenario, Flor A. Ceballo-Alcantara

The Philippine Agricultural Scientist

The sweet potato weevil, Cylas formicarius (Fabricius), is a devastating pest of sweet potato, Ipomoea batatas (L.) Lam., with a specific point of damage at the tuber where eggs are oviposited, and voracious larvae feed. Farmers in Tarlac province in the Philippines claim that a specific cultivar is highly infested by the pest, suggesting that other cultivars may not be susceptible to the pest damage. This study aimed to determine the reproductive biology of the weevil across 3 sweet potato cultivars (Inubi, Super Bureau, and Bureau) frequently grown in Central Luzon. Since the weevils are nocturnal, behavioral observations were conducted …

C*-Extreme Quantum Instruments; Completion And Disintegration Of Completely Positive Maps, Arghya Chongdar

Doctoral Theses

This thesis develops a comprehensive operator-algebraic framework for the study of completely positive (CP) instruments, with contributions spanning convexity theory, integration theory, completion problems, and disintegration theory. We begin by laying the foundational groundwork in the theory of C*-algebras and von Neumann algebras, introducing key structures such as CP maps, positive operator-valued measures (POVMs), and CP instruments, along with their dilation-theoretic properties. Pure and decomposable instruments are characterized via minimal bi-dilations, and CP instruments are realized as bivariate maps, providing a rigorous quantum analogue of classical joint measures. The thesis then investigates convexity-theoretic aspects of instruments. A structural characterization of …

A Detailed Jwst Exploration Of Gas Chemistry And Dust Within The Disk Of A Young Giant Planet, K. Ward-Duong, Mickaël Bonnefoy, Nathaniel Kerman, Kj Soto Villarreal, Nicole Arulanantham, Benoît Tabone, Catherine Dougados, Laurent Pueyo, Mathilde Mâlin, Et Al

Astronomy: Faculty Publications

We present near- to mid-infrared spectroscopy of the young (2 Myr), wide-orbit planetary mass companion SR 12 c, recently observed with JWST at unprecedented spectral resolution and sensitivity. With a mass of only 11 Jupiter masses, and a projected separation of nearly 1000 au from its cool (K+M type) binary host, SR 12 c represents an important and uniquely accessible case study of a circumplanetary disk. It is one of only three such objects detected to date in ALMA continuum observations, alongside the PDS 70 system and the free-floating planet OTS 44. Using JWST/MRS spectra at R3000, we characterize the …

Higher Uniformity Of Arithmetic Functions In Short Intervals Ii. Almost All Intervals, Kaisa Matomäki, Maksym Radziwiłł, Xuancheng Shao, Terence Tao, Joni Teräväinen

Mathematics Faculty Publications

We study higher uniformity properties of the von Mangoldt function Λ, the Möbius function μ, and the divisor functions dk on short intervals (x,x+H] for almost all x∈[X,2X]. Let Λ♯ and dk♯ be suitable approximants of Λ and dk, G/Γ a filtered nilmanifold, and F:G/Γ→C a Lipschitz function. Then our results imply for instance that when X1/3+ε≤H≤X we have, for almost all x∈[X,2X], (Formula presented.) for any fixed A>0, and that when Xε≤H≤X we have, for almost all x∈[X,2X], (Formula presented.) As a consequence, we show that the short interval Gowers norms ∥Λ−Λ♯∥Us(X,X+H] and ∥dk−dk♯∥Us(X,X+H] are also asymptotically small …

3dcotton, Md Ahmed Al Muzaddid, William J. Beksi

Agriculture - Archive

3DCotton is an image dataset consisting of 8 cotton plants recorded at the Texas A&M University Research Farm. The images were captured using an Apple iPhone at a resolution of 1040x1920 pixels. Approximately 150 images per plant were taken from a distance of 1 m by recording multiple viewpoints. These images can be utilized for developing 3D reconstruction methods.

Filtered Genome Of Commercial Philippine Varieties Of Sugarcane (Saccharum Officinarum L.) For The Characterization And Identification Of Ssrs Associated With Resistance To Philippine Downy Mildew (Peronosclerospora Philippinensis), Antonio G. Lalusin, Jhun Lawrence S. Rasco

The Philippine Agricultural Scientist

Sugarcane is a major global source of sugar, with total production reaching 1.89 billion t. Although the Philippines produces about 1.85 million t of sugarcane annually, yields are limited by downy mildew and smut. Developing varieties resistant to these pathogens is the most economical and practical approach to mitigating losses from these biotic stresses. In this study, SSRs related to disease resistance were developed through Next-Generation Sequencing (NGS) of the filtered genomes of sugarcane varieties with known phenotypic responses to downy mildew. Two assemblies based on minimum contig lengths (450 and 900 bp) were performed using SoapDeNovo2. The 900-bp assembly …

Marker-Assisted Identification Of Hybrids In Polyembryonic ‘Carabao’ Mango (Mangifera Indica L.) Breeding In The Philippines, John Edward L. Felipe, Kyla Andrea G. Mendoza, Benjamin Christian J. Esguerra, Carolyn E. Alcasid, Gino R. Hernandez, Eureka Teresa M. Ocampo

The Philippine Agricultural Scientist

Varietal improvement of the Philippine ‘Carabao’ mango (Mangifera indica L.) through conventional breeding is constrained by polyembryony, which makes it difficult to distinguish zygotic hybrids from nucellar seedlings at early developmental stages. This study evaluated the utility of simple sequence repeat (SSR) markers for early and accurate identification of hybrids in polyembryonic ‘Carabao’ mango crosses. Genomic DNA was isolated from 24 parental accessions and 61 putative hybrid seedlings using a modified CTAB protocol that yielded DNA suitable for PCR-based marker analysis. Eighty-one SSR markers were screened across 29 parental combinations, of which 64 markers (79.0%) were polymorphic in at …

Crop Performance Of Aromatic Basmati Rice Grown In Tidal Lands In Indonesia [Research Note], Riza Adrianoor Saputra, Indra Jatmika Liran, Yulia Padma Sari

The Philippine Agricultural Scientist

Rice production in Banjar Regency has declined in recent years due to land-limiting factors, particularly the suboptimal conditions of tidal wetlands. Therefore, improving cultivation techniques for new superior varieties such as Aromatic Basmati is essential to enhance productivity on marginal lands. This study aimed to determine the best combination of seedling number per planting hole and seedling age, as well as to evaluate the effect of each factor on the growth and yield of Aromatic Basmati rice cultivated on tidal land. The experiment was conducted for 4 mo (August to December 2020) in the experimental paddy fields of the Agricultural …

Spatial Variation In Soil Quality Across Selected Fruit Tree Plantations In Bacnotan, La Union, Philippines, Jay Mark G. Cortado, Roberto G. Visco, Jenielyn T. Padrones, Pastor L. Malabrigo Jr

The Philippine Agricultural Scientist

Sustaining soil quality on any plantation is critical to increasing productivity and responsible land use. However, spatial variation in soil quality across fruit tree plantations under existing field and management conditions remains insufficiently documented. This study aimed to assess the soil quality of monocropped plantations of banana, calamansi, coffee, and rambutan in northern Luzon, Philippines, evaluate the extent of degradation or improvement relative to a reference forest using the Soil Quality Index (SQI) approach, and identify the soil indicators that significantly influence soil quality in these plantations. The objectives were to determine which fruit tree plantations could enhance soil quality …

Postharvest Response Of Jute Mallow (Corchorus Olitorius L.) Tops To Different Storage Temperatures, Wella L. Absulio-Morales, James L. Tababa, Daphne Cassandra H. Gonzales, Genesis M. Banawa, Angelo C. Castro, Arlan James D. Rodeo

The Philippine Agricultural Scientist

Jute mallow (Corchorus olitorius L.), locally known as saluyot, is a nutrient-rich leafy vegetable, but its potential remains underutilized due to its high perishability. This study determined the postharvest behavior of jute tops stored at 4 different temperatures (5, 13, 20, and 28 °C). Key quality parameters were measured at specific time intervals. The marketable shelf life of jute tops was 7 d at 5 and 13 °C, but only 2 and 3 d at 28 and 20 °C, respectively. This shorter shelf life was mainly due to wilting caused by high weight loss, especially at higher temperatures. …

Application Of Information Literacy Skills To Everyday Life Information Seeking In College Students: Implications For Instruction, Stephanie Ward, Rachel Dineen, Darren Ilett

Communications in Information Literacy

Academic librarians who teach information literacy (IL) skills hope students will transfer those skills to their information seeking in everyday life. However, there is little evidence that students are transferring what they learn about research to their lives outside college. This study aims to find out what search and evaluation strategies college students who have had IL instruction apply to their own personal information seeking behaviors. To do this, a talk-aloud protocol was used to record participants’ thoughts and actions as they navigated scenarios that required them to select a source that met a non-academic information need. The findings indicate …

Evaluation Of Alternative Solvents For Electrospinning Occluded Scaffolds To Model Intracranial Atherosclerotic Disease In Blood Vessel Mimics, Olivia D. Rankin

Master's Theses

Intracranial atherosclerotic disease (ICAD) is characterized by a buildup of fatty plaque within the walls of arteries supplying the brain, resulting in vessel narrowing, restricted blood flow, and increased risk of ischemic stroke. While various treatments exist for ICAD, most are accompanied by high recurrent stroke rates and other adverse events, highlighting the need for further investigation and models for pre-clinical testing. Tissue engineered Blood Vessel Mimics (BVMs), consisting of a polymer scaffold sodded with human vascular cells, serve as physiologically relevant in vitro models for vascular device testing. This thesis focused on the application of alternative solvents to a …

Off-Label Neuroimaging, Jane C. Moriarty

Law Faculty Publications

The growth of neuroimaging evidence in the courtroom is consistent with the increased reliance on technical and machine-based specialties at trial. Litigants routinely seek to introduce neuroimaging evidence in both civil and criminal trials to supplement traditional medical, psychiatric, and psychological opinion testimony. A substantial portion of neuroimaging evidence is still in the developmental stage—what I term “off-label neuroimaging.” Unsurprisingly, evaluating the reliability of developing neuroimaging poses challenging questions for gatekeeping courts. Among the complex evidentiary issues neuroimaging presents for courts and litigants, this Article considers one foundational question: How should courts determine whether neuroimaging evidence is sufficiently reliable for …

Matlab Shake Table Control And Data Acquisition System, Abigail Austin

Architectural Engineering

The College of Architecture and Environmental Design’s (CAED) seismic laboratory shake table is used for earthquake engineering education and experimental testing. However, the existing control system is outdated and difficult for students unfamiliar with the system to operate. The objective of this project was to develop a MATLAB-based control and data acquisition application to simplify shake table operation and improve accessibility, of both operation and output, for student users.

The developed application imports earthquake acceleration records, scales the input motions to the operational limits of the shake table, and executes the desires motion through the existing hardware system. Experimental data …

2026 North American Forest Ecology Workshop Impact Report, Andrew Larson, Sharon Hood, Kim Davis, Justin Crotteau, Alina Cansler, Molly Mcdevitt, Carl Seielstad, Annie Oxarart, Kjersten Peterson

North American Forest Ecology Workshop Program

The 15^th North American Forest Ecology Workshop was held on the University of Montana campus in Missoula, Montana, June 23-26, 2026. The meeting attracted over 400 participants from across North America and beyond. This report summarizes attendance and participation, economic impacts, science delivery and professional development outcomes, and attendee feedback.

2026 North American Forest Ecology Workshop Program, Andrew Larson, Sharon Hood, Kim Davis, Justin Crotteau, Alina Cansler, Molly Mcdevitt, Carl Seielstad, Annie Oxarart, Kjersten Peterson

North American Forest Ecology Workshop Program

The 15^th North American Forest Ecology Workshop was held on the University of Montana campus in Missoula, Montana, June 23-26, 2026. The meeting attracted over 400 participants from across North America and beyond. The program featured plenary sessions, organized special sessions, topical workshops, trainings, and contributed oral and poster sessions, as well as multiple field trips.

Response To Kodali Et Al., “Hailey-Hailey Disease: A Review And An Approach To Management”, Christina Tolete, Teresa Duong, Adam Friedman, Leonardo Tjahjono

Department of Medicine Faculty Papers

No abstract provided.

The Gender Of International Criminal Law, Caroline L. Davidson

Michigan Journal of International Law

Notwithstanding the recognition of select gender-based crimes as international crimes and the International Criminal Court’s prosecutors’ professed commitment to seeking justice for gender-based crimes, core doctrines of international criminal law (ICL) obstruct accountability for gendered violence. This article identifies the overlooked gendered implications of a few substantive pillars of ICL: a de facto insistence on a connection to war (“war fetish”), a preoccupation with powerful men, and a focus on the “mastermind” of the crime to the exclusion of other culpable perpetrators.

These substantive pillars, some long-standing and some more recently erected, obscure the vast landscape of gender-based crimes and …

Development Of Kytc’S Context Classification Network, Jill Asher, Megan White, Eric Green, Christopher Van Dyke

Kentucky Transportation Center Research Report

Transportation agencies have adopted context-based classification systems that classify roadways based on the surrounding environment and user types. This offers a more comprehensive and multimodal perspective than traditional functional classification. While the Kentucky Transportation Cabinet (KYTC) has begun using project-level context classification, the agency will benefit from introducing network-level context classification. This will improve guidance, enhance project prioritization, and support the development of projects that better address the needs of all users. Responding to this need, Kentucky Transportation Center (KTC) researchers, in conjunction with KYTC staff, created a GIS-based model to build a context classification network that covers all state-maintained …

Electrically Evoked Emg Decomposition Using The Perturbative Generalized Series Expansion, William R. Walker

Master's Theses

Electrically evoked electromyography records the muscle's response to nerve stimulation and has been used for clinical assessment of neuromuscular function, as well as treatments such as functional electrical stimulation or stroke rehabilitation. In every muscular contraction, an electrical signal is generated. These signals come from the summation of simultaneously recruited motor units, enabling decomposition techniques to reveal information about motor unit recruitment.  By improving the ability to decompose and analyze these signals, clinical treatments involving neuromuscular electrical stimulation can be optimized and better understood. Much of the research on EMG analysis focuses on voluntary EMG, leaving a gap in the …

Ms110 Syllabus: Introduction To Computers, Information Systems, And Artificial Intelligence, Wei Zhang

Management Science and Information Systems Faculty Publication Series

This is a syllabus for Professor Wei Zhang's MS110: Introduction to Computers, Information Systems and Artificial Intelligence Course within UMass Boston's College of Management. This is an Open Educational Resource and can be remixed, copied, redistributed, altered and reused as long as permission is given to the original creator.

Comment On Opm’S Confidential Government Information Nondisclosure Agreement, Rachel Arnow-Richman, Mark Fenster, Jonathan F. Harris, Margaret B. Kwoka, Orly Lobel

UF Law Faculty Publications

This comment critically responds to the U.S. Office of Personnel Management's (OPM) May 2026 proposal to implement a government-wide nondisclosure agreement (NDA) for federal workers. Drawing from our scholarship on workplace governance, employee mobility, whistleblowing, and information controls, we argue that the OPM’s proposal is inconsistent with growing recognition of the risks associated with broad workplace secrecy agreements. Recent federal and state reforms limiting the use of NDAs recognize that such agreements can deter reporting, suppress information of public concern, and impede litigants and government actors from prosecuting wrongdoing. TThese concerns are especially salient in the context of public employment, …

Develop & Test Radar Assignments For Future Graduate Curriculum, Thomas Ky Hong, Christopher William Hoferer

Electrical Engineering

With Cal Poly’s switch to semesters, many upper-level electives lack enough depth and structured content for the new 15-week format. In addition, while the Electrical Engineering department currently offers approximately five weeks of RADAR-focused laboratory material within EE 424: Intro to Remote Sensing, this limited exposure is insufficient to provide students with a comprehensive understanding of RADAR theory and practical applications. The semester conversion presents a timely opportunity to expand this existing five-week RADAR segment into a full 15-week course that integrates both lecture and laboratory content. To address the current curriculum gap, we have seamlessly extended the RADAR exercises …