Digital Commons Network^™

The Impact Of Nicotine Pouches On Oral Health, Manas Mandal, Michael Moleski

Annual Research Symposium

Research Symposium

Retrospective Analysis Of Angiotensin Receptor Blockers And Knee Cartilage Volume In Osteoarthritis: Evidence From The Osteoarthritis Initiative, Parv Kale, Vijay Kale

Annual Research Symposium

No abstract provided.

Exploring The Potential Of Oncolytic Viruses As A Novel Therapeutic Approach For Breast Cancer Treatment, Renad Alsayyad, Claudia M. Tellez Freitas

Annual Research Symposium

No abstract provided.

Takotsubo Cardiomyopathy: A Case Of The Broken Heart, Lilian Huynh, Kaylee Putney

Annual Research Symposium

Takotsubo cardiomyopathy (TC), or "broken heart syndrome," is a rare cardiac condition causing temporary left ventricular dysfunction due to severe stress. Though the exact cause is unclear, it mimics myocardial infarction and can lead to cardiogenic shock. Current treatment lacks specific guidelines and relies on heart failure protocols. We report a case of a patient with TC-induced cardiogenic shock, likely triggered by emotional stress. She required vasopressors, a percutaneous intervention, an Impella device, and guideline-directed medication therapies. This case underscores the significance of establishing guideline optimizations for managing TC and cardiogenic shock.

Unh Research Team Finds Concentrated Pfas In Watershed Foams, Robbin Ray

Media Relations

No abstract provided.

In-Silico Modeling And Characterization Of Kcc2 Protein Interaction With A Small Molecule Direct Agonist Identifies Potential Binding Sites For Modulating Behaviors Associated With Substances Of Abuse, William Hai Dang Ho, Alfred Amendolara, Kenyon Mitchell, Jaden Miner, Ruth Northcott, Braxton Bingham, Andrew J. Payne

Annual Research Symposium

Purpose

KCC2 is a potassium-chloride cotransporter that plays a critical role in neuronal function by regulating GABAergic signaling via chloride gradients. Maintaining this concentration gradient is crucial for balancing excitation and inhibition in the brain. While KCC2 dysregulation has been implicated in epilepsy and seizures, recent studies suggest that KCC2 inhibition results in phenotypes mirroring those seen in chronic opioid dependence. As such, increasing evidence support KCC2 being a potential therapeutic target for modulating behaviors associated with substances of abuse. Currently, only a few direct small molecule agonists against KCC2 have been reported, and no definitive active site on the …

Evaluation Of Seven Commercially Available Dna Extraction Kits For Ocular Tissues, Jakob Newton, Conrad K. Ashby, Michael Trapnell, Triston Crook, Mark Eisele, Porter Biggs, Prina Patel, Christina Nelson, John A. Kriak, Kyle B. Bills, David W. Sant

Annual Research Symposium

2025 Annual Roseman Research Symposium

Sustainable Synthesis Of Cellulose-Derived Carbon Materials, Abbie S. Ganas

Sustainability Research & Creative Activities Grants Reports

Dr. Abbie Ganas, Chemistry, presents "Sustainable Synthesis of Cellulose-Derived Carbon Materials".

Vermonters Oppose Trump Executive Orders, Two-Thirds Disapprove Of Overall Performance 2/19/2025, Unh Survey Center

All UNH Survey Center Polls

President Donald Trump begins his second term with very low job approval ratings in Vermont, and most state residents disapprove of his handling of the economy and foreign policy. Majorities think Elon Musk's role in the administration is inappropriate and disapprove of the creation of DOGE. Vermonters also oppose many of Trump's other executive orders. Most state residents think the country is on the wrong track, but almost all Republicans think the country is headed in the right direction.

Republicans In Maine Ecstatic, Democrats Despondent, Over Direction Of Country In Early Days Of Trump Term 2/19/2025, Unh Survey Center

All UNH Survey Center Polls

President Donald Trump enjoys nearly unanimous approval of his handling of the economy, foreign policy, and his overall job performance among Maine Republicans but Democrats strongly disapprove. Mainers are considerably more likely than before Trump's inauguration to think the country is headed in the right direction, fueled by extremely high optimism among Republicans. Majorities of Mainers oppose Trump's executive orders revising birthright citizenship, withdrawing from the World Health Organization, and renaming the Gulf of Mexico. A majority think Elon Musk's current role in government is inappropriate and a plurality oppose the creation of the Department of Government Efficiency.

February 19, 2025 (Vol. 109, No. 19), Daily Eastern News

Daily Eastern News: 2024-2025

No abstract provided.

The Lumberjack, February 19, 2025

Cal Poly Humboldt's Student Newspaper

The student newspaper of Humboldt State University.

Tess Lorraine & Quinn Wubbena, Percussion Recital, February 19, 2025 [Program], University Of Northern Iowa. School Of Music.

Music Recital Programs

Program of a music recitals given by faculty, students, or guest artists from the School of Music at the University of Northern Iowa.

Lindenwood Digest, February 19, 2025, Lindenwood University

Lindenwood Digest

The Lindenwood Digest has been a digital employee newsletter since 2009.

Usa V. Khalil Vance

2025 Decisions

USDC for the District of New Jersey

Lisa Davenport V. Secretary Department Of Navy

2025 Decisions

USDC for the Middle District of Pennsylvania

Meeting Minutes 02-19-2025, Staff Advisory Council

Staff Advisory Council Meeting Documents

No abstract provided.

Silencing Faf2 Mitigates Alcohol-Induced Hepatic Steatosis By Modulating Lipolysis And Pcsk9 Pathway, Nazmul Huda, Praveen Kusumanchi, Yanchao Jiang, Hui Gao, Themis Thoudam, Ge Zeng, Nicholas J. Skill, Zhaoli Sun, Suthat Liangpunsakul, Jing Ma, Zhihong Yang

School of Medicine Faculty Publications

BACKGROUND: Chronic alcohol consumption leads to lipid accumulation, oxidative stress, cellular damage, and inflammation in the liver, collectively referred to as alcohol-associated liver disease (ALD). FAF2/UBXD8/ETEA (Fas-associated factor 2) is a ubiquitin ligase adaptor protein that plays a crucial role in the ubiquitin-mediated degradation of misfolded proteins in the endoplasmic reticulum. A recent genome-wide association study indicated an association between FAF2 and ALD; however, the exact contribution of FAF2 to ALD pathogenesis remains unclear. METHODS: FAF2 was knocked down using AAV-delivered shRNA in C57/BL6 mice. Mice were subjected to a chronic-plus-single binge ethanol feeding (NIAAA) model. Nine hours after gavage, …

Philharmonia Orchestra Concert: February 19, 2025, School Of Music,

School of Music Programs

Kemp Recital Hall

February 19, 2025

Wednesday Evening

7:30 p.m.

Librarian-As-Teacher: A Multiple Case Study Of Academic Librarian Professional Identity And Teaching Practice, Jessica Nicole Szempruch

USF Tampa Graduate Theses and Dissertations

The purpose of this qualitative multiple case study was to explore how the educational experiences and professional identities of academic librarians shape their approach to information literacy instruction within the context of post-secondary research universities. Through deep engagement with three academic librarian-teacher participants, the study sought to understand how information literacy instruction is enacted, administered, and experienced by these individual academic librarians. The quintain, or binding concept, connecting all of these cases was the intersection of academic librarian professional identity and information literacy instructional practice at a large, R1 institution in the southeastern United States.

Multiple data collection methods were …

A Bibliometric Study Of Astronomy And Geoscience Doctoral Dissertations, Nora Boyle, Mary Schlembach

Faculty Journal Articles

A bibliometric analysis was conducted over the bibliographies of astronomy and geology doctoral dissertations written between 1970 and 2020 in order to review the document types that are utilized and cited. An investigation was made of various cited reference ages and how cited references in dissertations have evolved with the advent of electronic resources and preprint services. Our study examined 50 astronomy and 50 geology dissertations with 10 dissertations selected from each decade (n = 100). Results measured included 13,475 total references and the study found that references to journal articles increased, and book citations have decreased in both …

Upcoming Unity Gala Provides Opportunity For Joy, Community, Jeffery Woodard

Press Releases 2020-2029

No abstract provided.

The Antelope, University Of Nebraska At Kearney

The Antelope

No abstract provided.

Examining The Relationship Between Frailty, Operative Management, And 90-Day Mortality Across Emergency General Surgery Conditions, Caleb W. Curry, Marisa R. Imbroane, Wyatt P. Bensken, Adam T. Perzynski, Christopher W. Towe, Vanessa P. Ho

Faculty Scholarship

No abstract provided.

Scalability Of A Graph Neural Network In Accurate Prediction Of Frictional Contact Networks In Suspensions, Armin Aminimajd, Joao Maia, Abhinendra Singh

Faculty Scholarship

Dense suspensions often exhibit shear thickening, characterized by a dramatic increase in viscosity under large external forcing. This behavior has recently been linked to the formation of a system-spanning frictional contact network (FCN), which contributes to increased resistance during deformation. However, identifying these frictional contacts poses experimental challenges and is computationally expensive. This study introduces a graph neural network (GNN) model designed to accurately predict FCNs by two dimensional simulations of dense shear thickening suspensions. The results demonstrate the robustness and scalability of the GNN model across various stress levels (s), packing fractions (f), system sizes, particle size ratios (D), …

Aging Is Associated With Decreased Lactobacillus And Increased Cervicovaginal Inflammation In Canadian Women, Ha T. Dang, Laura Noel-Romas, Samantha Knodel, Kenzie Birse, Hossaena Ayele, Alicia R. Berard, Adam D. Burgener, Christina Farr Zuend

Faculty Scholarship

Problem: Aging is characterized by a general dysregulation of systemic immune responses that increases susceptibility to infections and malignancies. Immune cells in the female genital tract (FGT) are regulated by sex hormones, but little is known about the impact of aging and menopause on immunology in the FGT. Method of Study: This study conducted an age-focused sub-analysis of cervicovaginal samples collected from 47 women enrolled in the Vaginal Mucosal Systems study in Winnipeg, Canada. Paired cervicovaginal lavage and cervical cytobrush were collected and analyzed by Luminex cytokine array, mass spectrometry based metaproteomics, metabolomics, and high dimensional flow cytometry. Results: The …

A Brief Introduction Of The Upi Method, Yoshihiko Ariizumi

Learning, Teaching, & Researching Optimization

This brief article introduces the UPI method which helps you to improve any skill, talent and ability.

Study To Understand The Effects Of Biofouling And Corrosion On Underwater Munitions: Implications For Risk Management And Resource Allocation, Center For International Stabilization And Recovery, Fenix Insight

Global CWD Repository

The project's primary objective is to understand the impacts of the underwater environment on munitions as a means to identify the residual risk these munitions pose, so people undertaking detection and clearance efforts can reliably assess operational risk and make informed decisions.

Early Career Awards Boost Work In Drag Reduction, Cellular Mechanics, Clara Turnage

University of Mississippi News

OXFORD, Miss. – The National Science Foundation has awarded its most prestigious early-career grant to two University of Mississippi researchers, recognizing their work in biomedical engineering and fluid dynamics.

How Effective Are Fact-Checks In Pakistan And Who Engages With Them?, Waqas Ejaz, Sacha Altay, Muhammad Ittefaq

School of Communication Studies - Faculty Scholarship

For fact-checks to be effective, they must first and foremost reach their intended audience. Yet, little is known about what determines engagement with fact-checks and how to enhance their reach. We conducted a pre-registered online survey experiment in Pakistan (N participants = 302, N observations = 1208) investigating the effectiveness of fact-checking, and the determinants of engagement with fact-checks and misinformation. We found that fact-checking reduced misperceptions, especially among the most misinformed. Trust was an important moderator of the effectiveness of fact-checking and of engagement with both the fact-checks and misinformation. For instance, fact-checks were more effective among participants who …