Digital Commons Network^™

Supporting New Teachers Through Mentorship And Collaboration, Nathan Bleeker

Masters Projects

High teacher turnover, especially within the first five years, negatively impacts student learning, school culture, and district budgets. Mentorship, administrative support, and professional development can help reduce attrition among beginning K–12 teachers in the United States. The project aims to identify practical, evidence-based strategies that support teacher retention during these critical early years. Through a review of existing theories and literature, the project will examine how structured and collaborative mentorship programs contribute to teacher satisfaction and commitment. School administrators can utilize project components, which include a handbook for teacher mentorship and organization document for collaborative opportunities, to help support on …

Vocal And Articulatory Speech Control Deficits In Individuals With Post-Stroke Aphasia, Roozbeh Behroozmand, Zeinab Khoshhal Mollasaraei, Vahid Nejati, Ayoub Daliri, Julius Fridriksson Ph.D.

Faculty Publications

Individuals with post-stroke aphasia exhibit deficits in regulating vocal (i.e., laryngeal) pitch control during speech vowel production; however, it is not determined whether such deficits also exist when they control their supra-laryngeal speech articulators during word production. To address this question, 19 subjects with post-stroke aphasia and 20 controls were tested under an altered auditory feedback paradigm in which they received + 30% shifts in their vowel first-formant frequency during word production. In addition, 17 aphasia subjects and 19 controls from the same groups also completed steady vowel vocalizations while receiving randomized pitch shifts at ± 100 cents. Consistent with …

Implementing The European Open Science Cloud (Eosc) In Ireland, William Brown, Christopher Burbidge, Diarmuid Collins, Aedin Culhane, Michelle Doran, Lindsay Dowling, Venkatesh Kannan, Beth Knazook, Ruth Patricia Moran, Joan Murphy, Flaithri Neff, Jenny O'Neill, Roberto Sabatino, Laura Whelan, Shirley Wrynn

Research Outputs: 2025-Present

This paper proposes the development of a European Open Science Cloud (EOSC) Federation national node for Ireland (EOSC Ireland). EOSC Ireland will be a digital platform that connects researchers and research infrastructures across Ireland to the European-wide EOSC Federation. It allows researchers to share and access data, tools, and applications, making national and international collaboration easier. By engaging with EOSC Ireland, researchers can find and contribute new datasets, share analysis, and provide analytical tool and code that others can use, helping to advance scientific discovery. To achieve this, EOSC Ireland must establish essential functions such as resource catalogue and registry …

Multifactorial Approach To Falls Prevention With Inclusion Of Morse Fall Scores & Artificial Intelligence Technology, Ruth Navarro, Andrea Tilleman, Lupe Almaguer, Grace Aguilera, Kristina Diaz-Rivas, Yesenia Quintero, Alex Vanegas, Jessica Amigot

All Publications

No abstract provided.

2025-04-17 Comments Made At The Executive Committee Meeting On Hb 424, Morehead State University. Faculty Senate.

Faculty Senate Records

Comments made at the Executive Committee Meeting on Kentucky House Bill 424 and submitted to the Faculty Senate on April 17, 2025.

2025-04-17 Committee Feedback On Strategic Plan Results, Morehead State University. Faculty Senate.

Faculty Senate Records

Committee Feedback on Strategic Plan Results and Prompts for Thought brought before the Faculty Senate on April 17, 2025.

2025-05-01 Faculty Senate Meeting Minutes, Morehead State University. Faculty Senate.

Faculty Senate Records

Faculty Senate meeting minutes from April 17, 2025.

Historicizing The Prison In The History Of Capitalism, James Parisot

Sociology Faculty Publications

The goal of this paper is to rethink the timeline through which scholars have conceived of the history of capitalism and imprisonment. Scholars including Oliver C. Cox, Fernand Braudel, and Giovanni Arrighi, among others, have presented a story of capitalism centered around the Italian-city states, followed by the Netherlands, Britain, and the United States. Yet discussions on the origins of capitalism and imprisonment, eventually resulting in the invention of the penitentiary as an institution of reform, usually start around the sixteenth century. Incorporating insights from both of these angles, this paper shows the historical ways that different centers of capitalist …

Sunset Park Lp V. Roberts

All Decisions

In this nuisance holdover proceeding, the landlord alleged two isolated incidents involving the tenant's guests "one in October 2023 involving a guest who banged on the apartment door, and one in February 2024 involving a verbal dispute in the lobby. The tenant moved to dismiss under CPLR § 3211(a)(7), arguing that the termination notice failed to state a cause of action for nuisance under Rent Stabilization Code § 2524.3(b). The court agreed, citing the settled principle that nuisance requires a pattern of recurring objectionable conduct. It found that the two incidents, months apart and involving guests rather than the tenant, …

Spectator 2025-04-17, Editors Of The Spectator

The Spectator

No abstract provided.

Faculty And Staff Library News - April 2025, Rit Libraries

RIT Digital Archives

No abstract provided.

Montana Kaimin, April 17, 2025, Students Of The University Of Montana, Missoula

Montana Kaimin, 1898-present

Student newspaper of the University of Montana, Missoula.

Novel Therapeutics For Myeloid Malignancies, Tim Kong

Arts & Sciences Graduate Student Theses and Dissertations

Myeloid malignancies are a group of heterogenous and clonal disorders that include myeloproliferative neoplasms (MPNs) and acute myeloid leukemia (AML). These blood cancers are driven by characteristic oncogenes and propagated by pro-inflammatory niches; MPNs demonstrate hyperactive JAK-STAT signaling and upregulate cytokines including TNF, IL-6, and IL-8. Current therapeutics such as ruxolitinib targeting JAK2 providing symptomatic benefit to MPN patients but are not curative and do not prevent disease transformation to acute myeloid leukemia (AML). As such, greater understanding of the underlying disease biology is still required with means of uncover cancer dependencies. Here, we utilize a series of multi-omic approaches …

The Pulse - April 17, 2025, Unm Hsc Marketing & Communications

The Pulse

Weekly newsletter of the UNM Health Sciences Center.

Enhancing Clinical And Academic Excellence With Clinical And Education Librarians, Evelyn Wang

HSLIC Faculty and Staff Instructional Resources

his presentation provides an overview of the Clinical and Education Librarian’s role at the University of New Mexico Health Sciences Library and Informatics Center (HSLIC). It details the librarian’s support for residents, faculty, and healthcare professionals in clinical practice, academic achievement, and research activities. The presentation highlights orientation for new residents, meeting support (including patient rounds, M&M conferences, journal clubs, and case discussions), research guidance (such as literature searching and citation management), and workshops on databases and tools like Zotero. The goal is to enhance clinical decision-making, streamline research, and empower patrons to efficiently access and manage information throughout their …

Effect Of Police Corruption On Former Residents Of The Philippines Upon Their Return To Their Homeland, Larry Dean Doyle

Walden Dissertations and Doctoral Studies

Corruption in law enforcement is particularly heinous because it deprives the citizens living under the threat of police corruption of the rule of law and takes away the constitutional protections that are guaranteed and enforced by the courts. The purpose of this qualitative phenomenological study was to explore the perceptions of former residents of the Philippines regarding the effect of police corruption on them. Schultz’s behavioral theories and the reward neurophysiology provided this study's framework. Data were collected from twenty-four surveys of former residents of the Philippines when they visited their homeland. Findings indicated that former residents of the Philippines …

A Comparative Analysis Of Demographic Characteristics Of Male Intimate Partner Violence Perpetrators, Katherine M. Thompson

Walden Dissertations and Doctoral Studies

Intimate partner violence is a significant and widespread social issue with far-reaching personal, societal, and economic consequences. Nonfatal strangulation is an act of violence that is considered a strong predictor of homicide within violent relationships. While research about nonfatal strangulation has improved, there is still limited knowledge about individuals who commit acts of strangulation within violent relationships. This study was an investigation of demographic characteristics of male individuals who commit acts of strangulation within intimate relationships. This research was grounded in the power and control theory, general strain theory, and social learning theory. The research questions for the study examined …

Assessing The Predictability Of Sexual Homicide Subtypes In Serial Homicide Offenders Using Childhood Abuse And The Macdonald Triad, Kevin Dionne

Walden Dissertations and Doctoral Studies

Prior research established a positive correlation between childhood abuse and sexually motivated murders, and childhood abuse is considered a risk factor for serial murder, especially for sexually motivated serial murder. The purpose of this quantitative study was to assess whether a predictive relationship exists between childhood abuse types (physical, sexual, and psychological) and MacDonald triad behaviors (enuresis, fire setting, and animal cruelty) in predicting sexual homicide subtypes (sexualized, grievance, and rape murder) in a sample of male serial sexual homicide offenders. The subtypes were derived from the Higgs, Carter, Tully, and Browne systematic review. The theoretical lenses applied in the …

The Psychological And Social Effects Of Asset Building Among Low-Income Consumers, Al Maurice Fleming

Walden Dissertations and Doctoral Studies

Low-income consumers face social and psychological barriers to economic self-sufficiency. This qualitative inquiry aimed to bridge the knowledge gap by examining how social and psychological factors that impede single mothers from achieving economic self-sufficiency. Grounded in Fishbein and Ajzen’s Theory of Planned Behavior (TPB), this study examined factors influencing single parents’ financial behaviors. The findings supported TPB, showing that financial literacy shapes intentions, perceived control increases with stability, and social norms influence financial behavior. Demographic questionnaires were administered, and structured interviews were conducted with 15 single African American mothers. The data was analyzed using themes, code annotations, and categorical classification. …

Treatments For Opioid Use Disorder: Perspectives Of Patients In Long-Term Recovery, Robert Florian

Walden Dissertations and Doctoral Studies

The contemporary landscape of substance use disorders, particularly opioid use disorder, presents a complex and pressing public health concern, marked by escalating rates of mortality and morbidity worldwide. Although extensive research has been conducted on the efficacy of interventions for opioid use disorder, a notable research gap exists concerning the perspectives of individuals in long-term recovery (defined as exceeding 2 years). Specifically, how these individuals view pharmacological and non-pharmacological treatment approaches remains largely unexplored in the existing literature. Grounded in the biopsychosocial model, this study investigates patients’ perceptions of medication-assisted treatment and abstinence-based therapies. Purposive sampling was utilized, and participants …

Lived Experiences Of School Counselors Regarding Applications Of Multicultural And Social Justice Advocacy, Michele Lynn

Walden Dissertations and Doctoral Studies

School counseling literature claimed that school counselors were trained in multicultural and social justice advocacy and were uniquely positioned within the school system as change agents. School counseling research had not explored school counselors’ experiences when applying their ethical responsibilities of multicultural and social justice advocacy. This hermeneutic qualitative phenomenological study explored the lived experiences of school counselors working in the education system regarding ethical practices of multicultural and social justice advocacy. The research question was: How do school counselors experience their social justice and multicultural advocacy roles within the education system? Three theories composed this study’s foundation: hermeneutic phenomenology, …

Prevalence Of Medical Writing In Hematological Malignancy Review Articles, Héctor A Vaquera-Alfaro, Elham Nasrollahi, Yashvin Onkarappa Mangala, David Russler-Germain, Aaron Goodman, Ghulam Rehman Mohyuddin

2020-Current year OA Pubs

BACKGROUND: Medical writing services, initially developed to streamline manuscript preparation, have raised ethical concerns due to their association with industry influence and spin. While prevalent in oncology and malignant hematology clinical trials, medical writing involvement in review articles remains underexplored, particularly in the hematology literature. Furthermore, conflict of interests of the writers may also affect the content of review articles. This study investigates the prevalence, characteristics, and funding sources of medical writing in malignant hematology review articles and their relationship with the financial conflicts of interest (CoI) among authors.

METHODS: We conducted a cross-sectional analysis of review articles published in …

April 17, 2025, James Madison University

The Breeze, 2020-

The Breeze is the student newspaper of James Madison University in Harrisonburg, Virginia.

April 17, 2025, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

Gray Matter Morphology And Pain-Related Disability In Young Adults With Low Back Pain, Jo Armour Smith, Rongwen Tain, Isaac Chrisman, Kelli G. Sharp, Laura M. Glynn, Linda R. Van Dillen, Jesse V. Jacobs, Steven C. Cramer

Physical Therapy Faculty Articles and Research

Structural neuroplasticity in the brain may contribute to the persistence of low back pain (LBP) symptoms and the disability associated with them. It is not known if structural adaptations are evident early in the lifespan in young adults with LBP. This study compared gray matter in cortical sensorimotor regions in young adults with and without persistent LBP and identified gray matter and clinical predictors of pain-related disability. Eighty-two individuals with and without a history of LBP participated. Peak and average gray matter density in cortical sensorimotor regions of interest was quantified using voxel-based morphometry. Pain-related disability, pain intensity, pain duration, …

Staying Safe When Taking Prescription Opioids, Aaron Hunt, Gabriela Murza, Amy May, Jenna Hawks, Alyssa Ferrin

All Current Publications

Prescription opioids, such as oxycodone, morphine, codeine, and hydrocodone, are often used for short-term pain management, and it is important to know how to keep yourself safe when taking opioids prescribed by a doctor. This fact sheet reviews what opioids are, how they work in the body, and how people become dependent on or overdose on opioids. It also offers how to limit your risk of dependence and suggests alternative pain management options.

Kras Mutation Detection By Liquid Biopsy For Pancreatic Ductal Adenocarcinoma, Mahmoud Yousef, Abdelrahman Yousef, Mark W Hurd, Ashwathy Pillai, Saikat Chowdhury, Mark Knafl, Paul M Roy, Mohammad Fanaeian, Sali Albarouki, Luca F Castelnovo, Jennifer Peterson, Brandon G Smaglo, Robert A Wolff, Shubham Pant, Jason Willis, Ryan Huey, Michael Overman, Ching-Wei Tzeng, Michael P Kim, Naruhiko Ikoma, Jess E Maxwell, Matthew H G Katz, Huamin Wang, Anirban Maitra, Eugene Koay, Ethan B Ludmir, Anthony Chen, Camila Lopez, Haoqiang Ying, John Paul Shen, Dan Zhao

Faculty, Staff and Student Publications

The clinical utility of liquid biopsy (LB) for pancreatic ductal adenocarcinoma (PDAC) remain understudied. Our single-institution cohort of 311 PDAC patients with non-tumor tissues informed LB found 81.2% positivity (N = 186) in metastatic cases and in 52.4% (N = 43) of localized disease. KRAS mutations were detected in 64.6% (N = 148) of metastatic cases and 16% (N = 13) for localized disease. Positive LB, especially KRAS mutation detection, is associated with worse overall survival (OS) in metastatic PDAC (median 14.5 vs. 31.3 months, HR = 2.7, 95%CI = 1.7-4.3, P <  0.0001). The positive concordance rates of KRAS and TP53 mutations were 63% and 68% in metastatic disease but only 7% (KRAS) and 33% (TP53) in localized disease, respectively. Among the 41 patients who underwent serial liquid biopsy testing, 25% tested positive after an initial negative result. LB detects therapeutically targetable mutations in 58.5% of PDAC patients and is associated with OS.

Reduced Venetoclax Exposure To 7 Days Vs Standard Exposure With Hypomethylating Agents In Newly Diagnosed Aml Patients, Christophe Willekens, Alexandre Bazinet, Samy Chraibi, Alex Bataller, Justine Decroocq, Benjamin Carpentier, Delphine Lebon, Abhishek Maiti, Nicolas Gauthier, Nicholas Short, Sarah Bonnet, Koji Sasaki, Sabine Khalife-Hachem, Mahesh Swaminathan, Jean-Baptiste Micol, Florence Pasquier, Christophe Marzac, Damien Roos-Weil, Laurent Pascal, Naval Daver, Tapan Kadia, Didier Bouscary, Farhad Ravandi, Arnaud Pages, Hagop Kantarjian, Stéphane De Botton, Courtney Dinardo

Faculty, Staff and Student Publications

Hypomethylating agent (HMA) plus venetoclax (VEN) regimens are standard of care in patients with acute myeloid leukemia (AML) ineligible for intensive chemotherapy. While the VEN label recommends continuous 28-day cycles, shortened VEN durations may induce similar response rates and improve tolerability. It is unknown how a VEN exposure reduced to 7 days during cycles compares to standard HMA + VEN. We retrospectively compared newly diagnosed AML patients treated with azacitidine (AZA) x 7 days plus VEN x 7 days ("7 + 7" regimen) from the first cycle (n = 82) vs patients treated with standard dose HMA + VEN (std-HMA/VEN) …

Multimeric Transcription Factor Bcl11a Utilizes Two Zinc-Finger Tandem Arrays To Bind Clustered Short Sequence Motifs, John R Horton, Meigen Yu, Jujun Zhou, Melody Tran, Rithvi R Anakal, Robert M Blumenthal, Yun Huang, Xing Zhang, Xiaodong Cheng

Faculty, Staff and Student Publications

BCL11A, a transcription factor, is vital for hematopoiesis, including B and T cell maturation and the fetal-to-adult hemoglobin switch. Mutations in BCL11A are linked to neurodevelopmental disorders. BCL11A contains two DNA-binding zinc-finger arrays, low-affinity ZF2-3 and high-affinity ZF4-6, separated by a 300-amino-acid linker. ZF2-3 and ZF4-5 share 73% identity, including five out of six DNA base-interacting residues. These arrays bind similar short sequence motifs in clusters, with the linker enabling a broader binding span. Crystallographic structures of ZF4-6, in complex with oligonucleotides from the β-globin locus region, reveal DNA sequence recognition by residues Asn756 (ZF4), Lys784 and Arg787 (ZF5). A …

Humanized Saccharomyces Cerevisiae Provides A Facile And Effective Tool To Identify Damaging Human Variants That Cause Exosomopathies, Khondakar Sayef Ahammed, Milo B Fasken, Anita H Corbett, Ambro Van Hoof

Faculty, Staff and Student Publications

The RNA exosome is an evolutionarily conserved, multiprotein complex that is the major RNase in 3' processing and degradation of a wide range of RNAs in eukaryotes. Single amino acid changes in RNA exosome subunits cause rare genetic diseases collectively called exosomopathies. However, distinguishing disease-causing variants from nonpathogenic ones remains challenging, and the mechanism by which these variants cause disease is largely unknown. Previous studies have employed a budding yeast model of RNA exosome-linked diseases that relies on mutating the orthologous yeast genes. Here, we develop a humanized yeast model of exosomopathies that allows us to unambiguously assess damaging effects …