Digital Commons Network^™

Overcoming Oxidative Cellular Senescence In High-Density Cell Bioreactor For Viral Vaccine Production Improving The Productivity, Hsian-Yu Wang, Yu-Jing Zeng

Cell Culture Engineering XIX

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Sammy Girón, Jazz Vocalist

Bailey School of Music Concert Programs

Sammy Girón, Jazz Vocalist

Luke Whitney, Violin

Bailey School of Music Concert Programs

Luke Whitney, Violin

Eric Jenkins, Piano

Cole Nelson, Oral History Interview, 2025, Kat Hacanyan

Oral Histories

Cole Nelson is an EMU alum who earned a degree in political Science in 2022. During his time at Eastern he worked in the Center for Jewish Studies with founding director, Marty Shichtman. Nelson worked closely with Shichtman, helping with things like event planning and updating the website. In this interview, he talks about his experiences at EMU, being hired as Shichtman's assistant, and how the center stayed afloat at the height of the Covid-19 pandemic.

Navigating The Shadows: Exploring The Interaction Between Social Progress And The Shadow Economy, Aziz N. Berdiev, James W. Saunoris

Mathematics and Economics Faculty Journal Articles

This paper uniquely examines the noneconomic dimensions of a nation’s overall wellbeing by focusing on social progress and its impact on the shadow economy. The shadow economy serves an important function in a market economy bysupplying goods and services that meet the social demands of society. We argue that deficits in social development, or social regression, prompt the expansion of the shadow economy. Employing cross-country panel data for 124 countries from 1991 to 2017 and two-way fixed effects instrumental variables estimation, the results show that advancements in social progress reduce the size of the underground sector. In terms of magnitude, …

The Philosopher’S Art: The Alchemical And Religious Writings Of Sir Isaac Newton, Caleb J. Stamp

Senior Honors Theses

Sir Isaac Newton is inarguably one of the most famous yet divisive geniuses in human history. His writing touched on a staggering variety of topics, including chemistry, physics, and history, among others. Some of his less well-known works – most notably, his alchemical experiments and his prophetic commentaries – have created wildly conflicting views of both him and his theories. However, Newton’s alchemical and religious writings are crucial to understanding his broader worldview: namely, that the spiritual and natural aspects of the world worked together in a universe created by a supreme God who ordained that reality operates in a …

Gospel Choir

Bailey School of Music Concert Programs

Oral Moses, Director

Kamaya Locke, Violin

Bailey School of Music Concert Programs

Kamaya Locke, Violin

Dr. Eric Jenkins, Piano

John Stagmeier, Violin

Bailey School of Music Concert Programs

John Stagmeier, Violin

Eric Jenkins, Piano

Creative Ties: Using Design To Build Connections And Reduce Loneliness, Madelyn Arnold

Honors Projects

While loneliness is a universal infliction, there are specific demographics that are disproportionately affected by this experience. The older adult population is at a much higher risk of experiencing feelings of loneliness and the negative health risks that come from extended periods of isolation. The severity of loneliness within the older adult population cannot be overstated. Art therapy techniques have been studied as a potential tool to reduce these feelings and side effects in this vulnerable population.

Moved by the profound effects and high rates of loneliness for older adults, this project seeks to create a tool to alleviate these …

Energy-Based Control Approaches For Weakly Coupled Electromechanical Systems, Najmeh Javanmardi, Pablo Borja, Mohammad Javad Yazdanpanah, Jacquelien M. A. Scherpen

School of Engineering, Computing and Mathematics

This paper addresses the stabilization and trajectory-tracking problems for two classes of weakly coupled electromechanical systems. To this end, we formulate an energy-based model for these systems within the port-Hamiltonian framework. Then, we employ Lyapunov theory and the notion of contractive systems to develop control approaches in the port-Hamiltonian framework. Remarkably, these control methods eliminate the need to solve partial differential equations or implement any change of coordinates and are endowed with a physical interpretation. We also investigate the effect of coupled damping on the transient performance and convergence rate of the closed-loop system. Finally, the applicability of the proposed …

Enhancing Physical And Mental Health For Children With Disabilities In Nicaragua, Grace Sudberry

Entry-Level Occupational Therapy Doctorate - Doctoral Capstone Symposium

The purpose of this occupational therapy doctoral project is to partner with FNE International in creating a unified soccer program that incorporates mental health education. In Nicaragua and around the world, there is a stigma behind mental health and access to care for mental health especially in children. One way to improve an individual’s overall mental well-being is through exercise. A quality improvement study consisting of quantitative and qualitative data collection determined the parents understanding of unified soccer and the importance of physical and mental health. Brief REDCap surveys and informal interviews were done to gather statistics and thematic analysis. …

Renewed Archaeological Research In Singida Region, Central Tanzania, Makarius Itambu, Eslem Ben Arous, Ricardo Fernandes, Marina Gallinaro, Jana Ilgner, Mary Lucas, Patrick Roberts, Erin Scott, Axel Steinhof, Robert Patalano

Biological and Biomedical Sciences Department Faculty Journal Articles

Archaeological research in central Tanzania, chiefly in the Singida Region, has only been sporadically conducted, with the focus of such investigations being mostly on rock art and Later Stone Age (LSA) material. Here, we report preliminary results from renewed research expeditions conducted in the Singida Region. In 2021 and 2022, we located 31 archaeological sites in Ikungi District, excavated an open-air site (Nkungi) and a rock shelter (Itramuka), and uncovered well-stratified cultural sequences containing lithics, ceramics, and metallurgical remains, as well as human remains and animal bones. The recent archaeological discoveries in the region revealed a rich and composite archaeological …

Management Of Recalcitrant Hypotension In Cocaine Positive Trauma Patient With Ich, Christopher Wojcik, Aladino De Ranieri, Moez Sumar

Advocate GME

Introduction: Peri-operative substance abuse presents various substance-specific challenges for anesthesia providers. Cocaine is a sympathomimetic alkaloid with two primary mechanisms of action including inhibition of monoamine re-uptake as well as blockade of sodium channels. Acute intoxication may manifest as agitation, hypertension, hyperthermia, tachycardia and tachyarrhythmias, and myocardial ischemia. At higher doses (3 mg/kg), cocaine has also been shown to have cardiovascular depressant effects. Chronic cocaine abuse results in peripheral catecholamine depletion and may manifest as hypotension or rebound hypertension. Case Presentation: A 30-year-old male with unknown past medical history presents after assault with a crowbar. Vitals showed SBP 150, HR …

Urgent Femoral Fracture Repair In A 106-Year-Old Oxygendependent Patient With Pulmonary Hypertension, Amir Siddiqui, Eva Martinez

Advocate GME

Introduction: Anesthetic management in very elderly patients with multiple comorbidities presents unique challenges. In this population, preserving cardiopulmonary stability and minimizing cognitive decline are paramount. Strategies that maintain spontaneous ventilation and maintain strict hemodynamic control can significantly impact perioperative outcomes. Case Presentation: 106-year-old female with a complex past medical history—pulmonary hypertension (pHTN) with elevated right ventricular systolic pressure (RVSP), oxygen-dependent COPD, HTN, HLD, prior CVA, CKD, Alzheimer’s dementia, and MDD following a fall at her care facility presented for urgent proximal femur repair. Her candidacy for neuraxial anesthesia was poor due to receiving a dose of prophylactic enoxaparin. Additionally, the …

Perioperative Management Of Life-Threatening Penetrating Thoracic Trauma, Mohammed Rashid, Simin Saatee

Advocate GME

Introduction: Thoracic trauma is a significant contributor to trauma-related mortality, accounting for approximately 25% of traumatic deaths in the United States[1,2]. The mechanisms of thoracic trauma are broadly categorized into penetrating and blunt injuries, each with distinct causes and clinical implications [2]. Case Presentation: This case involves a 22-year-old male who presented to the trauma bay after sustaining multiple gunshot wounds to the bilateral chest, epigastric region, and right arm. Upon initial assessment, the patient had a Glasgow Coma Scale (GCS) score of 13 and was hemodynamically stable. He had multiple bullet entry wounds to the chest, abdomen, and right …

Perioperative Management And Considerations Of Super-Morbid Patients In Back Surgeries, Isabel Rao Shuai, Katayoun Aghajani, Nebojsa Nick Knezevic

Advocate GME

Introduction: Obesity is an increasingly common condition. ASA classifies obesity based on BMI, with class 3 being BMI > 40. Class 3 obesity is associated with many comorbidities, thus increasing perioperative risk.[1] There are several recommendations for obese patients, however there are not many guidelines regarding super morbid patients. This case focuses on airway management and positioning. Case presentation: A 45 years female with medical history of asthma, thrombocytopenia, BMI of 89, 165cm of height came for lumbar-sacral ulcer debridement. She has been bedridden for 1 month after laparoscopic gastrectomy. She presented with decubitus ulcer that needed surgical debridement. Initially surgeon …

Symptomatic Hemi-Diaphragmatic Palsy Following Rescue Interscalene Brachial Plexus Nerve Block, Kishori Dhaku Bawdane, Liang Lozhou, Janhavi Dhargalkar

Advocate GME

Introduction: Proximal humerus/shoulder surgeries usually cause a significant amount of pain in post-operative period and Interscalene brachial plexus (ISB) nerve block promises good pain relief for the same. However, one of the major complications of the interscalene brachial plexus block is hemi -diaphragmatic palsy [1], which can pose a genuine concern for ambulatory surgeries. We hereby present a case of an elderly female who developed symptomatic right hemi diaphragmatic palsy after interscalene brachial plexus block. Case Presentation: This is a 73-year-old female with a past medical history of obesity (BMI 37), HTN, DM type II not on insulin, dyslipidemia, and …

Labor Analgesia Management Of A Patient With Charcote Marie Tooth Disease, Kishori Dhaku Bawdane, Farzad Ebrahimi, Janhavi Dhargalkar, Tian F. Yu

Advocate GME

Introduction: Charcot-Marie-Tooth disease (CMT) is one of the most common inherited sensory & motor polyneuropathies. Most patients present with distal muscle wasting and weakness. One-third of pregnant patients with CMT exhibit exacerbation of symptoms during pregnancy [1]. Anesthesia considerations for CMT are multiple, including variable effects of neuromuscular blocking drugs, reduced pulmonary reserve, difficult positioning etc. Limited data exists regarding use of neuraxial blockade in patients with CMT. We hereby present a case of 31-year-old female with CMT, who successfully received labor epidural analgesia for the vaginal delivery of her baby. Case Presentation: A 31-year-old female, Gravida1, Para 0 (G1P0) …

Metabolic Analysis Of Newly Established Chinese Hamster-Derived Cell Lines, Chl-Yn And Cho-Mk, Takeshi Omasa, Puriwat Sukwattananipaat, Sayaka Nagae, Noriko Yamano-Adachi

Cell Culture Engineering XIX

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Scalable And Automated Bioprocessing Strategies For Intensified Viral Vector Production In Hek293 Cell Culture, Omid Taghavian, Jose R. Sanchez, Shan Gao, Hamid Soleymani, Katsuko Sato, Chandana Sharma, Francisco Franco, Masafumi Nishino, Nozomu Tonoike

Cell Culture Engineering XIX

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Designing Cell Factories For Difficult To Express Proteins, Verónica S. Martínez, Zhuoqi Xiao, Irene Bharali, Marianne Gillard, Mary Otto, Jessica Cuthber, Min Zhang, Adrian Mazzone, Trent Munro, Lars K. Nielsen, Kym Baker, Esteban Marcellin, Verónica S . Martínez

Cell Culture Engineering XIX

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Demonstrating Key Processes Of The T Cell Therapy Workflow In Chemically Defined Media, Katsuko Sato, Shahram Shahabi, Anastassia Tselikova, Chandana Sharma

Cell Culture Engineering XIX

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Oxford Donors Support Cultural Destination, Tina H. Hahn

University of Mississippi News

OXFORD, Miss. – Oxford champions Patty and Will Lewis are giving to the Greenfield Farm Writers Residency project, the nonprofit stipend-supported writers residency being developed by the University of Mississippi.

An Exploration Of Behavioral Sex Differences Due To A Parkinsonian Gene, Pdr-1, In C. Elegans., Adriana Mulet Miranda, Mary B. Kroetz, Paul J. Kiser

Undergraduate Theses

Parkinson’s disease is a debilitating neurodegenerative disease of the central nervous system classified by the loss of dopaminergic neurons. Males and females exhibit different symptoms however, the cause remains unknown. Through the use of a model organism, C. elegans, we will investigate an ortholog of a Parkinsonian gene, pdr-1, to explore whether or not there are statistical differences between the hermaphrodites and males through known behavioral assays such as Swimming Induced Paralysis and Basal Slowing Rate. In order to compare gender differences, we successfully conducted CRISPR, where we inserted the him-8 mutation, resulting in an increased population …

Jtc 25: Achieving A Lifelong Dream, Staff Report

University of Mississippi News

This story is part of the 2025 Journey to Commencement series, which celebrates the pinnacle of the academic year by highlighting University of Mississippi students and their outstanding academic and personal journeys from college student to college graduate.

Glacier Runoff Impacts The Stoichiometry Of Riverine Nutrient Export From Coastal Alaskan Catchments, Jason Fellman, Eran Hood, Lee Ann Munk, Jordan Jenckes, Emily J. Whitney, Eric S. Klein

Faculty, Staff, and Students

Understanding the impacts of glacier change on riverine ecosystems is limited by a lack of multi-year studies in glacierized mountain catchments quantifying the magnitude and stoichiometry of riverine biogeochemical yields. Here we evaluate riverine concentration-discharge relationships using the power function between daily runoff and element yields and stoichiometry across 10 catchments of varying glacial coverage within two climatically distinct regions in the Gulf of Alaska. Our multi-year study showed that biogeochemical stoichiometry and concentration-discharge relationships for dissolved carbon, nitrogen, and phosphorus varied significantly with catchment glacier coverage across both regions. This stoichiometric variability could drive regional differences in proglacial riverine …

Mundane, Ordinary And Eerie Undertones, Yixuan Xia

Theses

When people encounter fear and uncertainty, their mental and physical reactions can vary. Drawing from my personal experience and the ‘Uncanny Valley’ theory [2], I explore various materials and juxtapose ordinary elements with unsettling imagery. In this project, I focus on donuts, transforming them by adding surreal details to imbue them with eerie undertones. For example, in one of my works, a delicious-looking donut appears perfectly normal at first glance. When viewers have a close look at the donut, its surface is crawling with worms, creating an unsettling contrast between the familiar and the disturbing. By altering these familiar items, …

Systemization Of Knowledge (Sok): Goals, Coverage, And Evaluation In Cybersecurity And Privacy Games, Yue Huang, Marthie Grobler, Lauren S. Ferro, Georgia Psaroulis, Sanchari Das, Jing Wei, Helge Janicke

Research outputs 2022 to 2026

This paper systematized existing knowledge on cybersecurity and privacy game-based approaches, exploring their goals, scope, and evaluation methods. Our review of 93 academic papers revealed that these approaches serve multiple purposes and target diverse player types. We identified 11 key aspects of cybersecurity and privacy that these approaches addressed, such as threats, defensive strategies, and data privacy. Additionally, we analyzed the effectiveness evaluation methods of these approaches, emphasizing the connections between evaluation techniques, types of data used, and their alignment with the approaches' goals. We also summarized the aspects of user experience evaluated in the literature and the types of …

Senior Recital, Kaya O'Brien-James, Tania Fleischer

Honors Thesis

Featuring research on the lives of Giacomelli, Vivaldi, Brahms, Mozart, Duparc, Bolcom, and Schwartz. The music is analyzed for context in romantic relationships and history. This recital was presented as a culmination of works learned by senior voice major, Kaya O'Brien-James.