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Single Vesicle Surface Protein Profiling And Machine Learning - Assisted Dual Image Analysis For Breast Cancer Detection, Mitchell Lee Taylor May 2025

Single Vesicle Surface Protein Profiling And Machine Learning - Assisted Dual Image Analysis For Breast Cancer Detection, Mitchell Lee Taylor

Electronic Theses and Dissertations Archive

Single vesicle molecular profiling of cancer-associated EVs is increasingly recognized as a powerful tool for cancer detection and monitoring. Mask and target dual imaging offers a straightforward method to quantify the fraction of molecularly targeted EVs in biofluids at the single vesicle level. However, accurate and efficient dual imaging analysis remains challenging due to interference from false signals in mask images and the need to process large volumes of clinical sample data. A fully automated dual imaging analysis method based on machine learning, integrated with dual imaging single-vesicle technology (DISVT), for breast cancer detection at various stages is presented here. …


Linking Neural And Physiological Indicators Of Turn-Taking: The Importance Of Live Engagement, Brandon Alexander Copping May 2025

Linking Neural And Physiological Indicators Of Turn-Taking: The Importance Of Live Engagement, Brandon Alexander Copping

Electronic Theses and Dissertations Archive

Introduction: Many turn-taking studies examine measures from temporal, neural, or respiratory domains separately as well as limit the turn-taking behaviors participants can engage in by dictating when and for how long they are allowed to speak. A multi-domain approach that does not restrict when participants are allowed to respond would be able to bridge these gaps. Objectives: Determine whether the presence of a live presenter elicits more ecologically valid response times in a question-answer paradigm than the use of pre-recorded audio. Also, determine whether participants begin executing speech motor plans upon recognition of answer-relevant information or upon detection of a …


Optimal Placement Of Electric Vehicle Charging Stations Using Modified Artificial Hummingbird Algorithm In An Electric Grid, Sravan Kumar Dumpeti May 2025

Optimal Placement Of Electric Vehicle Charging Stations Using Modified Artificial Hummingbird Algorithm In An Electric Grid, Sravan Kumar Dumpeti

Electronic Theses and Dissertations Archive

The rapid adoption of Electric Vehicles (EVs) necessitates to optimize the grid through strategic placement of Electric Vehicle Charging Station (EVCS). Conventional algorithms such as Greywolf Optimization Algorithm and Particle Swarm Optimization have been used for the placement of EVCS, but they have difficulties in dealing with dynamic and complex environments. With this background, this thesis proposes a Modified Artificial Hummingbird Algorithm (MAHA) for optimal placement of EVCS in the IEEE 9-bus, 57-bus, and 118-bus systems. The first approach uses a single objective function that minimizes transmission losses due to EV charging, while the second approach considers a multi-objective function …


The Interplay Of Poetry And Musical Style In Ned Rorem's Song Cycle Aftermath: A Reflection Of His Quaker And Pacifist Beliefs, Brianna Marie Reilly May 2025

The Interplay Of Poetry And Musical Style In Ned Rorem's Song Cycle Aftermath: A Reflection Of His Quaker And Pacifist Beliefs, Brianna Marie Reilly

Electronic Theses and Dissertations Archive

This document is an analysis of the contemporary ten-movement song cycle Aftermath, written by Ned Rorem. Aftermath was composed in 2002 as a commentary on the terrorist attacks that occurred on September 11, 2001, in the United States of America and explores themes of loss, grief, survival, and reflection. This document includes historical information about the attacks of September 11, 2001, biographical information on Ned Rorem, information on the texts and the poets whose works Rorem integrated into Aftermath, and an analysis of the musical and textual elements utilized. As Rorem is a Quaker and a Pacifist, each song in …


Faculty Senate Xxx 2024-2025 - May 5, 2025 Agenda, Faculty Senate May 2025

Faculty Senate Xxx 2024-2025 - May 5, 2025 Agenda, Faculty Senate

Faculty Senate Agendas & Minutes

No abstract provided.


Soon-To-Be University Of Dayton Graduates Show Perseverance, Resilience, University Of Dayton May 2025

Soon-To-Be University Of Dayton Graduates Show Perseverance, Resilience, University Of Dayton

News Releases

Cynthia Bukirwa's 8,300-mile journey to graduation began with a 13-hour bus ride from her native Uganda to Nairobi, Kenya, on her way to Columbus, Ohio, to reunite with her mom after five years. Her next stop, inspired by her mom, is medical school.


Libby Hilsenrath V. School District Of The Chathams May 2025

Libby Hilsenrath V. School District Of The Chathams

2025 Decisions

USDC for the District of New Jersey


685 1st Ave Llc V. Cai May 2025

685 1st Ave Llc V. Cai

All Decisions

In this lease expiration holdover, the landlord sought possession after the tenant failed to execute a renewal lease offered via an online platform. The landlord claimed exemption from RPL § 226-c's notice requirement, arguing its earlier lease offer (below a 5% increase) precluded the need for further notice. The court disagreed, finding that once the landlord decided not to renew the lease, it was obligated to serve a written nonrenewal notice. The court also held that electronic lease offers did not satisfy statutory notice requirements because they violated the lease's specific notice provision requiring service by mail. Additionally, the lease …


Vocal Toning Increasing The Parent-Child Bond In Neonatal Care: A Proposed Method, Mikki Mcintire May 2025

Vocal Toning Increasing The Parent-Child Bond In Neonatal Care: A Proposed Method, Mikki Mcintire

Expressive Therapies Theses

Vocal toning in the Neonatal Intensive Care Unit (NICU) is an innovative therapeutic method that greatly improves emotional connections between caregivers and fragile infants. This practice is more than just a new idea; it fosters the crucial relationships essential for developing newborns. Vocal toning also aids in stabilizing physiological responses and promoting emotional regulation in infants, who are often subjected to high-stress situations. Using structured vocalization techniques, caregivers can provide consistent auditory and vibrational cues that encourage relaxation and promote co-regulation with the infants in their care. This proposed approach examines the theoretical foundation, solid methodology, practical application, and anticipated …


The Effects Of A Helmet Cooling Fan On Productivity In Healthy Males During A Simulated Work Task In The Heat, Siya Patel, Douglas Casa, Monique Marcelino May 2025

The Effects Of A Helmet Cooling Fan On Productivity In Healthy Males During A Simulated Work Task In The Heat, Siya Patel, Douglas Casa, Monique Marcelino

Honors Scholar Theses

Rising global temperatures and heatwaves are forcing labor workers to work in hot indoor and outdoor environments that can lead to life-threatening heat-related injuries. These injuries impair physical and cognitive performance, negatively affecting worker performance and efficiency. To help manage the adverse effects of heat stress on workers, cooling strategies have been implemented to prevent increase in body temperature and improve work performance. These strategies include heat acclimation, proper hydration, cooling garments, cooling helmets and more. However, research on helmet cooling fans on mannequins shows conflicting results regarding its effectiveness in improving work performance. Therefore, this study aimed to investigate …


Oriented Matroid Circuit Polytopes, Jodi Mcwhirter May 2025

Oriented Matroid Circuit Polytopes, Jodi Mcwhirter

Arts & Sciences Graduate Student Theses and Dissertations

Matroids give rise to several natural constructions of polytopes. Inspired by this, we examine polytopes that arise from the signed circuits of an oriented matroid. We give the dimensions of these polytopes arising from graphical oriented matroids and their duals. Moreover, we consider polytopes constructed from cocircuits of oriented matroids generated by the positive roots in any type A root system. We give an explicit description of their face structure and determine the Ehrhart series. We also study an action of the symmetric group on these polytopes, giving a full description the subpolytopes fixed by each permutation. These type A …


A Curriculum To Foster Self-Management Through Morning Meetings, Emily Auld May 2025

A Curriculum To Foster Self-Management Through Morning Meetings, Emily Auld

Masters Theses/Capstone Projects

The purpose of this capstone is to create a curriculum for morning meetings that foster self-management skills in 5th grade students. I have created a four-week curriculum that addresses self-management skills for students in 5th grade, although, this curriculum can be easily adjusted to fit the needs of students in younger grades. This curriculum was created using the research I have outlined in my literature review. Additionally, this curriculum uses The Collaborative for Social and Emotional Learning (CASEL) framework guide my curriculum.


The Impact Of Maternal Mental Health On Child Development, Jessica White May 2025

The Impact Of Maternal Mental Health On Child Development, Jessica White

Nursing | Student Research Posters

No abstract provided.


Evaluating The Impact Of Initial Injury Severity On Post-Traumatic Joint Contracture In A Rat Elbow Model, Genevieve Jarrell May 2025

Evaluating The Impact Of Initial Injury Severity On Post-Traumatic Joint Contracture In A Rat Elbow Model, Genevieve Jarrell

Mechanical Engineering and Materials Science Independent Study

Post-traumatic joint contracture (PTJC) is a common complication following elbow injuries, often leading to stiffness, pain, and impaired limb function. A simple elbow dislocation model in Long-Evans rats has been validated to replicate clinical PTJC. However, real-world elbow trauma frequently involves more complex injuries such as chronic instability or fracture dislocation. The objective of this study was to evaluate outcomes of two newly developed, more severe elbow injuries in vivo for the first time. A three-tiered injury model of increasing severity was implemented: Tier I (simple dislocation), Tier II (instability), and Tier III (fracture dislocation). Mechanical hyperalgesia thresholds, forelimb strength, …


Unam Magnum Scutellam De Onichio: The Many Lives Of The Tazza Farnese, Merrick L. Gormley May 2025

Unam Magnum Scutellam De Onichio: The Many Lives Of The Tazza Farnese, Merrick L. Gormley

Classical Mediterranean and Middle East Honors Projects

The Tazza Farnese is a large-scale sardonyx phiale (a shallow bowl) with a diameter of about 22 centimeters. The Tazza has caught the attention of numerous historical figures throughout antiquity, but despite how coveted the object may have been, records of its provenance before the 1400s are dissatisfactory or entirely nonexistent. This project seeks to shape a number of clear, thorough timelines for the object, as a synthesis of the many conflicting scholarly theories for its chronology. Furthermore, it examines the Tazza in the contexts of the cultures it was immersed in and investigates the way it was interpreted by …


Building Rapport, Encouraging Intrinsic Motivation, And Reducing Anxiety With Labor-Based Grading Labor-Based Grading: More Rapport, Less Anxiety, Gwyneth E. Cliver May 2025

Building Rapport, Encouraging Intrinsic Motivation, And Reducing Anxiety With Labor-Based Grading Labor-Based Grading: More Rapport, Less Anxiety, Gwyneth E. Cliver

Foreign Languages and Literature Faculty Publications

Since fall 2021, the author has practiced a method of ungrading, labor-based contract grading, in all courses in the small German program at the University of Nebraska at Omaha. The author has anecdotally observed less anxiety, fewer incidents of cheating, more cooperation among students, stronger rapport between students and instructors, growth of minors and majors, and more excitement and energy in the program. To familiarize the German language acquisition community with the literature, the article presents a comprehensive review of the harms of normative grading practices and the theories backing and questioning ungrading methods as alternatives. The mixed-methods study used …


Understanding Potential Profitability Estimates For Western Kentucky Grain Production, Austin Randolph, Naveen Musunuru May 2025

Understanding Potential Profitability Estimates For Western Kentucky Grain Production, Austin Randolph, Naveen Musunuru

Honors College Theses

Profitability remains a persistent challenge for grain farmers across the United States and globally. Without profitability, the continued operation of any grain farm becomes unsustainable. For grain farmers, profitability is not merely a financial goal but a crucial determinant of their livelihood. However, many grain producers face a significant obstacle: a lack of reliable tools to predict profitability and plan for the next season or make adjustments to existing operations. While budgets can offer a framework and tentative guidelines for farmers to follow, fluctuations in market prices can ultimately undermine these financial plans. The objective of this project is to …


Implementation Of Classroom Technology For Elementary Students With Adhd, Melanie Flemming May 2025

Implementation Of Classroom Technology For Elementary Students With Adhd, Melanie Flemming

Walden Dissertations and Doctoral Studies

The problem addressed in this study is the teacher-reported increase in behavioral problems among students with attention-deficit hyperactivity disorder (ADHD) since a mandated introduction of educational technology in the classroom aimed at improving student performance. Using the PICRAT (passive, interactive, creative, replacement, amplification, transformation) describes the impact of technology on a teacher's previous practice model as the conceptual scaffold, this study was conducted to explore teachers’ experiences integrating educational technology and any corresponding student behavioral changes in classrooms that include students with ADHD. Following a basic qualitative design, data were collected through semistructured interviews, using a self-designed interview protocol, with …


Faculty Perceptions Of Challenges To Faculty Retention In Workforce Training Programs At A Higher Education Center In The Southern United States, Brea Terry May 2025

Faculty Perceptions Of Challenges To Faculty Retention In Workforce Training Programs At A Higher Education Center In The Southern United States, Brea Terry

Walden Dissertations and Doctoral Studies

The problem addressed in this study is the challenges of retaining faculty in the workforce training program division at a higher education center in the southern United States. The purpose of this basic qualitative study was to explore faculty perceptions regarding challenges to faculty retention in the workforce training program division at a higher education center in the southern United States and their recommendations for improved faculty retention. The conceptual framework that supported the study was Maslow’s hierarchy of needs theory. Data were collected through semistructured interviews with eight full-time workforce training faculty members who had been employed with the …


Karats And Styx: Perceptions Of Value Amongst Ntt Faculty And The Creation Of Status Divisions Through Contingent Appointments, Autumn Lockwood Payton, Susan Weaver, Laura Heller, Samantha Bowman, Maria Gillotti, John Koertje May 2025

Karats And Styx: Perceptions Of Value Amongst Ntt Faculty And The Creation Of Status Divisions Through Contingent Appointments, Autumn Lockwood Payton, Susan Weaver, Laura Heller, Samantha Bowman, Maria Gillotti, John Koertje

Reports from the Gender Equity Research Fellowship

This research investigates how women, transgender, and gender nonconforming professional faculty perceive their value in the university relative to their male counterparts. Shifting demographic trends and competition for tuition-paying undergraduates has forced institutions of higher learning, especially regional private universities, to restructure faculty appointments, increasing the proportion of faculty hired into contingent roles. These roles are disproportionately occupied by women and gender nonconforming individuals (as a group). To address the question of whether value is understood differently based upon gender, we draw upon a mixed-methods approach, administering a campus-wide survey to professional faculty and conducting interviews and focus groups to …


Skid Row To Recuperation Constellation, Nafisa Azad May 2025

Skid Row To Recuperation Constellation, Nafisa Azad

Bachelor of Architecture Theses - 5th Year

California suffers from more homelessness than any other state in the U.S. This is also true of chronic homelessness – a critical category of homelessness that captures the intersection of homelessness and disability. Indeed, homelessness and disability – both physical and mental - often occur together. This intersection is especially prevalent in Los Angeles. Current approaches to homelessness focus on housing, with insufficient attention paid to the oft equally troublesome disabilities that follow suit. The dearth of attention paid to the intersection between homelessness and disability represents a crucial gap to be filled. This thesis aims to demonstrate how community …


Dust To Dream, Brenda Meloto De Oliveira May 2025

Dust To Dream, Brenda Meloto De Oliveira

Bachelor of Architecture Theses - 5th Year

This thesis explores the design and implementation of a holistic housing initiative to address the needs of economically disadvantaged populations in Sertão do Moxotó, Pernambuco. Situated in an arid region with limited resources, the project provides not only shelter but also community spaces, educational opportunities, and essential services to improve local living standards.

The region’s history of resilience is reflected in its vernacular architecture, which uses materials like adobe, rammed earth, and thatch—offering sustainable, climate-adapted solutions. Yet, basic amenities remain out of reach for many. Community-led initiatives, non-monetary systems, and vocational training help bridge these gaps and empower individuals to …


The Slice / Revitalizing Space For Bushwick's Creatives, Nadabya Lorick May 2025

The Slice / Revitalizing Space For Bushwick's Creatives, Nadabya Lorick

Bachelor of Architecture Theses - 5th Year

Bushwick has an underlying heritage of being a vital, diverse, energetic neighborhood. Declining infrastructure, fragmented social networks, and a lack of attention to residents’ needs have contributed to the area’s struggles. Despite these challenges, the neighborhood’s vibrant street art culture has emerged as a powerful force for renewal, fostering a sense of identity and drawing widespread appreciation. Reconfiguring a person’s relationship with their existence in Bushwick, NY, sits at the intersection of the wider well-being of humans, which includes intrinsic elements and more social interaction. This looks like repurposing buildings to highlight Bushwick’s unique blend of historical heritage, artistic energy, …


Sardis - The Agonist: A Monument To The Resurrection Of A Dormant Cultural & Commercial Center, Inocencio Ruiz May 2025

Sardis - The Agonist: A Monument To The Resurrection Of A Dormant Cultural & Commercial Center, Inocencio Ruiz

Bachelor of Architecture Theses - 5th Year

The rural American Southeast is a region of deep cultural significance that is shaped by resilience, adaptation, and an ever-evolving relationship with the land. Sardis, like many crossroad towns in Georgia, bears the imprint of shifting economies, environmental forces, and the enduring spirit of its people. This thesis combines a familiar vernacular of place that is integrated with a neo-cultural sophistication to explore how material details become the foundation for composing and proposing a neo-narrative architecture that represents a people, a region, and its rural southern heritage.

Sardis, Georgia is a complex and historically important small town... the materiality that …


Novel Combination Therapies For Estrogen Receptor-Positive Breast Cancer Driven By Rational Molecular Mechanisms, Anneka Lila Johnson May 2025

Novel Combination Therapies For Estrogen Receptor-Positive Breast Cancer Driven By Rational Molecular Mechanisms, Anneka Lila Johnson

Dartmouth College Ph.D Dissertations

Breast cancer (BC) is the most common non-keratinocyte cancer diagnosed in women in the United States with approximately 300,000 new cases diagnosed each year. Despite a myriad of treatment options, BC remains the second-most deadly cancer. Estrogen receptor-positive (ER+) BC comprises 60-70% of BC diagnoses and is treated with endocrine therapies that limit ER signaling. Despite endocrine therapy options, ~1/3 of patients experience recurrence within 10-20 years of diagnosis. Novel therapeutic strategies are required to limit BC recurrence-related morbidity and mortality.

Radiotherapy is used as an adjuvant treatment for ER+ BC patients prior to the use of endocrine therapy. Radiation …


Estimating Pedestrian Crossing Times At Scramble Crossings Via Machine Learning And Agent-Based Modeling, Sho Takami May 2025

Estimating Pedestrian Crossing Times At Scramble Crossings Via Machine Learning And Agent-Based Modeling, Sho Takami

Honors Capstones

Scramble crosswalks differ from conventional crosswalks in their ability for pedestrians to cross diagonally. This research compares the average crossing times and investigates the walking behaviors that pedestrians adopt to produce the speediest times in the two crosswalk configurations. Identification of the most efficient set of walking behaviors is done through an agent-based model, whereas producing polynomials relating crossing times to the most prominent walking behaviors is done through regression algorithms in machine learning. With the combination of these two approaches, it is revealed that pedestrians must adopt a relaxed walking style to make each crosswalk configuration efficient. Additionally, between …


The George-Anne Daily, Georgia Southern University May 2025

The George-Anne Daily, Georgia Southern University

George-Anne Media Group: Newsletters & Magazines

No abstract provided.


Titan Class Of 2025 Celebrated During Commencement, Julia Perez May 2025

Titan Class Of 2025 Celebrated During Commencement, Julia Perez

Press Releases 2020-2029

No abstract provided.


Mitochondrial Network Expansion And Loss During Oligodendrocyte Life And Death, Xhoela Bame May 2025

Mitochondrial Network Expansion And Loss During Oligodendrocyte Life And Death, Xhoela Bame

Dartmouth College Ph.D Dissertations

Oligodendrocytes are the myelinating cells of the central nervous system, known for modulating signal transmission, refining neural circuits, and providing metabolic support to axons. Oligodendrocytes are generated throughout life from oligodendrocyte precursor cells (OPCs) and are damaged or lost in demyelinating and neurodegenerative diseases and age-related pathologies. Thus, understanding the cellular checkpoints that occur during the generation and degeneration of oligodendrocytes is crucial for maintaining their population in health and recovering it in disease and aging.

Using high-resolution optical imaging, I have discovered a dynamic redistribution and subcellular partitioning of mitochondria during oligodendrogenesis. Mitochondria transiently expanded towards the differentiating OPC …


Multifunctionality, Aahanaa Tibrewal May 2025

Multifunctionality, Aahanaa Tibrewal

Art and Art History Honors Projects

Multifunctionality is a project that explores the intersection of art and design through a versatile dining table that transforms into a gaming table. Built with accessibility in mind and using red oak for its warmth and grain, the table features a rolling tambour top that serves as a dining surface when closed and reveals a felt-covered gaming area when open. This piece was shaped by my needs and the desire to create a space for connection and shared experiences. This project reflects my broader approach to art – constantly exploring new materials and methods, driven by curiosity and a love …