Digital Commons Network^™

Effects Of Healthcare Administrators And Icu Nurses’ Perspectives Of Leader Bullying On Work And Physical Six Sigma/Lean Training, Agha Raza

Walden Dissertations and Doctoral Studies

Despite the U.S. government-funded initiatives, public responsiveness, and antibullying legislation to improve healthcare, leadership bullying behavior remains a serious concern in hospital intensive care units (ICUs). The ICU nursing involves high stress levels and hospital work conditions, which lead to bullying behaviors. When ICU nurse leaders do not participate in work and physical Six Sigma/Lean training, they may develop different perceptions of leaders’ bullying behavior compared to those whose leaders participate in this training. The purpose of this nonexperimental quantitative cross-sectional survey study was to discover any significant relationships between the type of Six Sigma/Lean training (descendant, ascendant, and horizontal) …

Behavioral Health Leadership’S Role In Enhancing Family Reunification Success In Residential Care., Porscha Profitt

Walden Dissertations and Doctoral Studies

This qualitative case study examined the role of behavioral health leadership (BHL) in facilitating effective family reunification within residential treatment settings, focusing on Organization X in Northern California. The study addressed the persistent issue of high recidivism rates among youth with intellectual and co-occurring mental health disorders following discharge from therapeutic foster care. Using the Baldrige Excellence Framework as a guiding model, the research explored how BHLs assess reunification success, engage families, and navigate systemic and individual challenges that hinder sustainable transitions to home environments. Data collection involved semi-structured interviews with administrators and supplemented by organizational documents and reports. Thematic …

Cervical Cancer Screening Overuse Among Women With And Without Disability In The U.S. From 2007 To 2016, Preeti Zanwar, Chan Shen, Matthew Smith

College of Population Health Faculty Papers

INTRODUCTION: Persons with disability, a recognized health disparity population with complex care needs, may be at risk for cervical cancer screening overuse. However, limited studies have examined cervical cancer screening overuse among women with and without disability using large nationally representative survey data. Among women with and without disability, the authors aimed to provide national estimates of cervical cancer screening overuse and the proportion of cervical cancer screening overuse among younger, middle-age, and older women.

METHODS: The authors first utilized the U.S. Preventive Services Task Force guidelines to conceptualize and define cervical cancer screening overuse for women with and without …

Structural And Molecular Basis Of Pcna-Activated Fan1 Nuclease Function In Dna Repair, F. Li, A. S. Phadte, M. Bhatia, S. Barndt, A.R. Monte Carlo, Iii, C.F.D. Hou, R. Yang, S. Strock, A. Pluciennik

Department of Biochemistry and Molecular Biology Faculty Papers

FAN1 is a DNA dependent nuclease whose proper function is essential for maintaining human health. For example, a genetic variant in FAN1, Arg507 to His hastens onset of Huntington's disease, a repeat expansion disorder for which there is no cure. How the Arg507His mutation affects FAN1 structure and enzymatic function is unknown. Using cryo-EM and biochemistry, we have discovered that FAN1 arginine 507 is critical for its interaction with PCNA, and mutation of Arg507 to His attenuates assembly of the FAN1-PCNA complex on a disease-relevant extrahelical DNA extrusions formed within DNA repeats. This mutation concomitantly abolishes PCNA-FAN1-dependent cleavage of such …

I Knew You Were Trouble When You Walked In: The Negative Effects And Shortcomings Of United Nations Peacekeeping Efforts, Andrea G. Heredia-Ortiz

Honors Program Theses and Research Projects

The purpose of this paper is to look at peacekeeping operations done by the United Nations. In specific the efforts in Haiti, the former Yugoslavia, and Israel. In each of these operations the United Nations created more instability or left the country in the same or worse state than it was when it came in. In the case of Haiti there was sexual exploitation of the citizens and the cholera outbreak of 2010. In Israel, the peace operation has been ongoing since 1947, conflict in the Middle East does not seem to be coming at an end anytime soon. Additionally, …

Setting Sail For Resilience And Ocean Sustainability, Alun Morgan, Charlotte Braungardt

School of Law, Humanities and Social Sciences

This paper makes a valuable contribution to the emerging field of marine social sciences by focusing on the potential contribution of learning theory and praxes in promoting Ocean Literacy, Marine Identity and Marine Citizenship. These are advocated as important social dimensions of the changes and outcomes required to promote sustainability and resilience of marine environments and, by extension, terrestrial environments, across a range of scales from local through to planetary. This is because the factors that compromise marine resilience are largely anthropogenic, and negative outcomes of human disassociation from the ocean. From another perspective, the paper is equally concerned with …

Secondary Syphilis Case Report: Septic Arthritis And Tendinopathy, Phil Kulpinski

Advocate GME

No abstract provided.

Law School News: Rwu Law Teams Earn Top Honors At National Admiralty Moot Court Competition 4-2-2025, Helga Melgar

Life of the Law School (1993- )

No abstract provided.

Law School News: From The State House To The Court House 4-22-2025, Andrew Clark, Roger Williams University School Of Law

Life of the Law School (1993- )

No abstract provided.

Law School News: Rwu Law Ranked #11 Nationally For Most Graduates In Public Interest Law Careers 4-15-2025, Helga Melgar

Life of the Law School (1993- )

No abstract provided.

Law School News: Better Than He Found It 4-24-2025, Danna Lorch, Roger Williams University School Of Law

Life of the Law School (1993- )

No abstract provided.

The Cost Of Leadership: Giving Voice To The Experiences Of Student Leaders Of Color At Predominantly White Institutions, Gustavo F. Burkett

Graduate Doctoral Dissertations

The Cost of Leadership: Giving Voice to the Experience of Student Leaders of Color at Predominantly White Institutions

August 2025

Gustavo F. Burkett, B.S., The University of Maine

M.Ed., The University of Maine

Ph.D., University of Massachusetts Boston

Directed by Professor Tara Parker

The way many predominantly white institutions (PWIs) have positioned cultural student organizations as representations of campus diversity, often disguises the complex, racialized burdens carried by the organization’s student leaders. Leadership roles held by students of color are embedded in administrative structures not built with their identities in mind. This study explored the intersection of race, institutional culture, …

Immunotherapy With Nebulized Pattern Recognition Receptor Agonists Restores Severe Immune Paralysis And Improves Outcomes In Mice With Influenza-Associated Pulmonary Aspergillosis, Jezreel Pantaleón García, Sebastian Wurster, Nathaniel D Albert, Uddalak Bharadwaj, Keerthi Bhoda, Vikram K Kulkarni, Mbaya Ntita, Paris Rodríguez Carstens, Madeleine Burch-Eapen, Daniela Covarrubias López, Jania Foncerrada Lizaola, Katherine E Larsen, Lauren M Matula, Seyed J Moghaddam, Yongxing Wang, Dimitrios P Kontoyiannis, Scott E Evans

Faculty, Staff and Student Publications

Influenza-associated pulmonary aspergillosis (IAPA) is a potentially deadly superinfection in patients with influenza pneumonia, especially those with severe disease, underlying immunosuppression, corticosteroid therapy, or requiring intensive care support. Given the high mortality of IAPA, adjunct immunomodulatory strategies remain a critical unmet need. Previously, the desensitization of pattern recognition pathways has been described as a hallmark of IAPA pathogenesis and a predictor of mortality in IAPA patients. Therefore, we studied the impact of nebulized Toll-like receptor 2/6/9 agonists Pam2 CSK4 (Pam2) and CpG oligodeoxynucleotides (ODNs) on infection outcomes and pulmonary immunopathology in a corticosteroid-immunosuppressed murine IAPA model. Mice with IAPA receiving …

Forward Genetic Screen In Zebrafish Identifies New Fungal Regulators That Limit Host-Protective Candida-Innate Immune Interaction, Bailey A Blair, Emma Bragdon, Gursimran Dhillon, Nnamdi Baker, Lena Stasiak, Mya Muthig, Pedro Miramon, Michael C Lorenz, Robert T Wheeler

Faculty, Staff and Student Publications

Candida is one of the most frequent causes of bloodstream infections, and our first line of defense against these invasive infections is the innate immune system. The early immune response is critical in controlling Candida albicans infection, but C. albicans has several strategies to evade host immune attack. Phagocytosis of C. albicans blocks hyphal growth, limiting host damage and virulence, but how C. albicans limits early recruitment and phagocytosis in vertebrate infection is poorly understood. To study innate immune evasion by intravital imaging, we utilized the transparent larval zebrafish infection model to screen 131 C. albicans mutants for altered …

Theta Oscillons In Behaving Rats, M S Zobaer, Nastaran Lotfi, Carli M Domenico, Clarissa Hoffman, Luca Perotti, Daoyun Ji, Yuri Dabaghian

Faculty, Staff and Students Publications

Recently discovered constituents of the brain waves—the oscillons—provide a high-resolution representation of the extracellular field dynamics. Here, we study the most robust, highest-amplitude oscillons recorded in actively behaving male rats, which underlie the traditional θ-waves. The resemblances between θ-oscillons and the conventional θ-waves are manifested primarily at the ballpark level—mean frequencies, mean amplitudes, and bandwidths. In addition, both hippocampal and cortical oscillons exhibit a number of intricate, behavior-attuned, transient properties that suggest a new vantage point for understanding the θ-rhythms’ structure, origins and functions. In particular, we demonstrate that oscillons are frequency-modulated waves, with speed-controlled …

Genome-Wide Allele-Specific Expression In Multi-Tissue Samples From Healthy Male Baboons Reveals The Transcriptional Complexity Of Mammals, Ramesh Ramasamy, Muthuswamy Raveendran, R Alan Harris, Hiep D Le, Ludovic S Mure, Giorgia Benegiamo, Ouria Dkhissi-Benyahya, Howard Cooper, Jeffrey Rogers, Satchidananda Panda

Faculty, Staff and Students Publications

Allele-specific expression (ASE) is pivotal in understanding the genetic underpinnings of phenotypic variation within species, differences in disease susceptibility, and responses to environmental factors. We processed 11 different tissue types collected from 12 age-matched healthy olive baboons (Papio anubis) for genome-wide ASE analysis. By sequencing their genomes at a minimum depth of 30×, we identified over 16 million single-nucleotide variants (SNVs). We also generated long-read sequencing data, enabling the phasing of all variants present within the coding regions of 96.5% of assayable protein-coding genes as a single haplotype block. Given the extensive heterozygosity of baboons relative to humans, we could …

Identifying Developmental Intellectual Disability As A Sudep Risk Marker From Epilepsy Monitoring Unit Reports Using Large Language Models, Ran Hu, Rashmie Abeysinghe, Gorbachev Jowah, Shiqiang Tao, Samden D. Lhatoo, Guo-Qiang Zhang, Licong Cui

Faculty, Staff and Student Publications

No abstract provided.

Direct Parieto-Occipital Connectivity Of The Amygdala Via The Parahippocampal Segment Of The Cingulum Bundle, Arash Kamali, Kamand Khalaj, Atif Ali, Farbod Khalaj, Diana Kokash, Andres R Gonzalez, Michael A Jacobs, Alireza Akhbardeh, Paul E Schulz, Khader M Hasan

Faculty, Staff and Student Publications

Background

The amygdala is a key structure involved in memory, emotional processing, and sensory integration. While the cortical connectivity of the amygdala with the frontal and temporal lobes has been extensively studied, its direct connections with the parieto-occipital cortices remain underexplored. This study aims to delineate the direct connectivity between the amygdala and the parietal and occipital cortices via the parahippocampal segment of the cingulum bundle.

Methods

High-resolution diffusion-weighted imaging (DWI) tractography was performed on 30 healthy adult brains. Fiber tracking was conducted using three regions of interest (ROIs) placed in the parietal, occipital, and medial temporal lobes. A fractional …

Clinical And Fundamental Research Progressions On Tumor-Infiltrating Lymphocytes Therapy In Cancer, Jiandong Hu, Mengli Jin, Weihong Feng, Barbara Nassif-Rausseo, Alexandre Reuben, Chunhua Ma, Gregory Lizee, Fenge Li

Faculty, Staff and Student Publications

Malignant tumors represent a significant threat to human health. Among the various therapeutic strategies available, cancer immunotherapy-encompassing adoptive cell transfer (ACT) and immune checkpoint blockade therapy-has emerged as a particularly promising approach following surgical resection, radiotherapy, chemotherapy, and molecular targeted therapies. This form of treatment elicits substantial antigen-specific immune responses, enhances or restores anti-tumor immunity, thereby facilitating the control and destruction of tumor cells, and yielding durable responses across a range of cancers, which can lead to the eradication of tumor lesions and the prevention of recurrence. Tumor-infiltrating lymphocytes (TILs), a subset of ACT, are characterized by their heterogeneity and …

Determination Of Chlorpheniramine Maleate In Its Pharmaceutical Preparations Using Homemade Turbidity Flow Injection Analyzer, Muntadhar M. Jabbar, Elham N. Mezaal

Baghdad Science Journal

By using continuous flow injection analysis technology, a new analytical method was presented for the determination of chlorpheniramine maleate (CPM) in its pure form and in some of its pharmaceutical preparations. The study was based on the reaction of CPM with ammonium ceric(IV) sulphate (ACS) in an acidic medium, where the reaction resulted in a slightly yellowish white precipitate. It was studied using Ayah 6S × 1-ST-2D solar cell CFI analyzer (homemade) by measuring the light reflected from the surfaces of precipitate particles at (0–180°). Several experiments were conducted to study and improve the chemical and physical parameters. The correlation …

An Assessment Of Inorganic Contaminants Levels In The Wastewater Of Lifting And Treatment Sewage Stations In Karbala, Iraq, Mohammed Nasser Hussain, Ahmed Fadhil Khudhair, Hussain Jawad Ahmed

Baghdad Science Journal

The investigation in this study includes examining the impact of wastewater at ten different stations. Eight lifting stations and two treatment stations in the center and district of Al-Hurr in the Karbala city. The study’s goal is to determine the operational effectiveness of the main treatment unit project in Karbala and the Al-Hurr treatment unit and its impact on wastewater quality, disclosing the qualitative features of wastewater in the study area, controlling waste water from treatment plants, and utilizing its service in other fields. More than 70 trace elements were examined in this study by using inductively coupled plasma mass …

Preparation Of Novel Adsorbents Via Functionalized Mcm-41 Prepared From Plant Residues, Raghad Saad Hatem, Hayder Hamied Mihsen, Alaa Frak Hussain

Baghdad Science Journal

In this study, mesoporous silica MCM-41 was functionalized with 3-aminopropyltriethoxysilane (APTES) to obtain MCM-41@APTES, which contains primary amine groups. In the next step, 5-bromosalicylaldehyde was refluxed with MCM-41@APTES in toluene to obtain the Schiff base-functionalized mesoporous silica material, MCM-41@APTES-BSAL. MCM-41@APTES and MCM-41@APTES-BSAL were characterized via FT-IR, FESEM-EDX, TEM, N2-adsorption-desorption, XRD, and TGA/DTA. The XRD and TEM investigations showed that MCM-41@APTES and MCM-41@APTES-BSAL were generated with extremely ordered hexagonal arrangements. The findings from the N2-adsorption–desorption analysis revealed that the average pore diameters, total pore volumes, and specific surface areas were 7.530 nm, 0.292 cm³g^-1, and 155.19 m …

Synthesis And Characterization Of New Petroleum Demulsifies From Poly Acryl Amide With Poly Vinyl Alcohol And Studying Photolysis, Zaynab Hussein Fadel, Sura K. Ibrahim, Sana Hitur Awad, Faris Hamood Mohammed

Baghdad Science Journal

One of the most important problems associated with oil production is the formation of stable (water-in-oil) emulsions, and these emulsions greatly affect the process of treating the oil and ridding it of water.The creation of these emulsions throughout the oil production process is an expensive state, and the low water level of crude oil emulsions enhances performance while lowering the risk of equipment and pipeline deterioration. One technique to lower the water content is to break down crude oil emulsions chemically by demulsification. The water droplets quickly collide because the emulsifier renders the thin film separating the water droplets and …

Cover-Crop Effects On Near-Surface Soil Physical Properties,Infiltration, And Nematodes Over Time In The Lower Mississippiriver Valley, Cooper Fanning, Kristofor R. Brye, Mike Daniels, Trenton L. Roberts, Sam Fernandes, Lisa Wood

Crop, Soil and Environmental Sciences Faculty Publications and Presentations

Human population growth and climate change are stressors that continue to put pressure on current agricultural production systems. Cover crops (CC) as a means to improve soil health remain widely underused, particularly in the Lower Mississippi River Valley. The objective of this study was to evaluate the effects of CC on the change over time in near-surface bulk density, aggregate stability, total infiltration and steady-state infiltration rate, and nematode populations in eastern Arkansas. Averaged across depth, bulk density did not change over time under a no cover crop (NCC) treatment, but increased approximately 0.03 g cm-3 over time under CC. …

Molecular Characterization And Predictors Of Relapse In Patients With Ph + All After Frontline Ponatinib And Blinatumomab, Nicholas J Short, Hagop Kantarjian, Ken Furudate, Nitin Jain, Farhad Ravandi, Omer Karrar, Sanam Loghavi, Lewis Nasr, Fadi G Haddad, Jayastu Senapati, Rebecca Garris, Koichi Takahashi, Elias Jabbour

Faculty, Staff and Student Publications

Background: Several studies have suggested that chemotherapy-free regimens consisting of blinatumomab and a BCR::ABL1 tyrosine kinase inhibitor are highly effective in Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph + ALL). However, the clinical and molecular characteristics that predict for relapse with these chemotherapy-free regimens are largely unknown.

Methods: We conducted a prospective phase II clinical trial of the combination of blinatumomab and ponatinib in 76 patients with newly diagnosed Ph + ALL. Patients received 12-15 doses of intrathecal chemotherapy as central nervous systemic (CNS) prophylaxis. The patterns of relapse and the clinical and molecular predictors of relapse were analyzed.

Results: With …

The Genestar Manual For Biospecimen Collection Biobanking And Omics Data Generation From Commercial Space Missions, Aparna Krishnavajhala, Marie-Claude Gingras, Emmanuel Urquieta, Hsu Chao, Dilrukshi Bandaranaike, Yi Chen, Sravya Bhamidipati, Viktoriya Korchina, S Michelle Griffin, Michal M Masternak, Hannah Moreno, Javid Mohammed, Mullai Murugan, Jennifer E Posey, Jimmy H Wu, Donna Muzny, Richard A Gibbs, Harsha Doddapaneni

Faculty, Staff and Students Publications

The surge in commercial and civilian spaceflight enables the systematic and longitudinal, large-scale biospecimen collection to understand the prospective effects of space travel on human health. The Genomics and Space Medicine (Space Omics) project at BCM-HGSC involves a comprehensive biospecimen collection plan from commercial/private space flight participants. The manuscript addresses the critical gaps in the biospecimen collection process including details of the informed consent process, a provision for subjects to obtain custom CLIA-WGS reports, a data dictionary and a LIMS enabled biobank. The manuscript also discusses the biospecimens collection, processing methodologies and nucleic acid suitability for Omics data generation. Results …

Recent Advances In The Utilization Of Cellulose From Food Processing Byproducts For The Generation Of Aerogels, Jaspreet Kaur, Ali Ubeyitogullari

Food Science Faculty Publications and Presentations

Aerogels have garnered significant attention from the scientific community due to their extraordinary properties, including low density, high porosity, low thermal conductivity, and large surface area. These properties make them interesting candidates for diverse applications such as thermal insulation, drug delivery, catalysis, fillers, tissue engineering, and biosensors. However, the production of conventional aerogels is often constrained by environmental issues, the high cost of raw materials, and energy-intensive fabrication methods. In contrast, cellulose aerogels have emerged as promising sustainable materials with the potential to transform various low-cost waste products into high-value biomaterials. Food-processing byproducts provide numerous untapped opportunities for the generation …

Solitary Fibrous Tumor Of The Pancreas: An Exceedingly Rare Tumor Presentation, Matthew Posen, Krishna Shah, Ahmad Mardini, Ernst Joachim, Samee Farooqi, Tarek Almouradi

Advocate GME

No abstract provided.

Therapeutic Left-To-Right Shunting In Heart Failure, Francesco Fioretti, Ajith P Nair, Stefan D Anker, Barry A Borlaug, Dean J Kereiakes, Joann Lindenfeld, Gregg W Stone, Javed Butler

Faculty, Staff and Students Publications

Heart failure with reduced or preserved ejection fraction is associated with elevated left atrial pressure at rest due to fluid overload or during exercise, leading to pulmonary venous congestion. Even with available treatments, heart failure hospitalizations remain high, and improvements in quality-of-life scores and functional capacity are modest. Thus, there is growing interest in non-pharmacological methods to decompress the left atrium and improve heart failure symptoms and outcomes. Left-to-right shunts have emerged as a potential therapeutic option to reduce left atrial hypertension, improve quality of life, and impact long-term outcomes. This nascent field carries both potential therapeutic promise and many …

Autophagy Is Required For The Therapeutic Effects Of The Nad+ Precursor Nicotinamide In Obesity-Related Heart Failure With Preserved Ejection Fraction, Mahmoud Abdellatif, Moydul Islam, Abhinav Diwan, Et Al.

2020-Current year OA Pubs

No abstract provided.