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News From Uab Libraries, 06 2025, Uab Libraries

UAB Libraries News

No abstract provided.

Basal Autophagy Promotes Accurate Chromosome Segregation In Drosophila Oocytes And Declines During Oocyte Aging, Diana C. Hilpert

Dartmouth College Ph.D Dissertations

The frequency of trisomic pregnancies exponentially increases with advanced maternal age, a phenomenon known as the maternal age effect. The majority of these aneuploid pregnancies arise from meiotic segregation errors in the oocyte and premature loss of sister chromatid cohesion is a contributing factor. However, the mechanisms that lead to premature cohesion loss during oocyte aging are not fully understood.

Using Drosophila melanogaster as a model organism, work described in this dissertation demonstrates that basal levels of autophagy, a degradation process for damaged organelles and protein aggregates, are required during meiotic prophase for arm cohesion maintenance and accurate meiotic segregation …

Whole-Exome Sequencing Identified Molecular Variants Linked To The Progression Of Gastric Precancerous Lesions In Patients From Southwestern Colombia—An Exploratory Approach., Lizeth Mejia-Ortiz, Jovanny Zabaleta, Jone Garai, Luis Eduardo Bravo, Andres Castillo

School of Graduate Studies Faculty Publications

No abstract provided.

Lost And Found: The Forgotten Origins Of The “Cruel And Unusual Punishments” Prohibition, John D. Bessler

Articles

The U.S. Supreme Court and legal scholars have long traced the origins of the Eighth Amendment’s prohibition against “cruel and unusual punishments” to the English Declaration of Rights, codified as the English Bill of Rights (1689). The English Declaration of Rights recited that, in King James II’s reign, “illegal and cruel punishments” had been “inflicted,” with its tenth clause then declaring in hortatory fashion: “That excessive bail ought not to be required, nor excessive fines imposed, nor cruel and unusual punishments inflicted.” The prohibitions against excessive bail and excessive fines and the final phrase—“nor cruel and unusual punishments inflicted”—were later …

The Moving Pieces Of Corporate Disclosure: Truth, Falsity, And Half-Truths In Between, Donald C. Langevoort

Georgetown Law Faculty Publications and Other Works

The half-truth doctrine is made operational in the common statutory and rule-based admonitions in the securities laws (particularly Rule 10b-5) not to omit “material fact[s] necessary in order to make . . . statements made . . . not misleading . . . .” It cabins the temptation to exploit the privilege of nondisclosure through what has been called “artful paltering.” Unfortunately, the evolution of the half-truth doctrine has become more of a poor stepsister than a muscular companion. It carries less than a full load in the complex ecosystem that exists for public company disclosure today. And it is …

Assessing The Relationship Between Combat Exposure, Wartime Service, And Barriers To Substance Use Disorder Treatment In Post 9/11 Veterans., Robert Near

Dissertations

Substance use disorders (SUDs) represent a critical public health concern, particularly within military and veteran populations. The complex interplay of mental health challenges, combat exposure, and the unique stressors associated with military service contribute to a heightened vulnerability among veterans. Research from the United States Department of Veterans Affairs (USDVA) underscores the prevalence of these issues, indicating that approximately 1 in 10 veterans from the Iraq or Afghanistan wars treated by the VA are diagnosed with a SUD (Veterans Affairs, 2023). Additionally, veterans from all eras show a higher propensity for binge drinking when compared to the general population, further …

The Rose That Grew From Concrete: Exploring The Romantic Experiences Of Black Men With Histories Of Childhood Sexual Abuse, Tatyana Nichelle Smith

Dissertations

Contemporary research typically characterizes Black heterosexual relationships by dismal marriage and divorce rates, largely ignoring the reality of how Black men develop attachments with their romantic partners and therefore continuing to perpetuate deficit perspectives of Black men (e.g., the cause of conflictual romantic relationships and “broken” Black families). What may be less understood about these relationships is the influence of childhood trauma, such as childhood sexual abuse, and Black men’s experiences of gender role conflict. Research shows that Black men’s experiences of childhood sexual abuse and socialization about masculinity have important implications for how they come to view themselves and …

Rotating Scatter Mask System Optimization Study For Determining Optimal Image Recreation, Seth L. Grover

Theses and Dissertations

The Rotating Scatter Mask (RSM) system is a radiation imaging technology currently limited by the mask design and governing identification algorithm parameters. To optimize the RSM design, Dakota—an optimization software—was integrated with a ray tracing code that simulates particle interactions with the RSM detector, and with the Locally Competitive Algorithm (LCA), which reconstructs the source image based on the ray tracing code’s Detector Response Matrix (DRM). Since the original ray tracing code was developed in MATLAB, it was translated into Python to improve compatibility with both Dakota and LCA. The Python version of the ray tracing code was then integrated …

Fused-Silica Microelectromechanical Systems For Relative Gravimetry, Ethan Doerstling

Theses and Dissertations

Gravimeters are devices that measure gravitational acceleration which can be used by the United States Air Force (USAF) in the areas of navigation and remote sensing. Fused-silica microelectromechanical systems (MEMS) devices offer capabilities to make inexpensive relative gravimeters with higher thermal stability than common silicon devices while maintaining good gravitational sensitivity. The fused-silica devices in this research were designed, simulated, fabricated, and tested to observe their performance as gravimeters. The devices exhibit properties of highly sensitive accelerometers but the current designs do not qualify as gravimeters. This study provides information to improve the sensitivity and stability of these fused-silica MEMS …

A Vacuolar Proton Pump Controls The Post-Germinative Growth Of Rice (Oryza Sativa Ssp. Japonica), Peter James Icalia Gann, Soumen Nandy, Rodrigo Botelho, Kari Vinzant, Mariya Khodakovskaya, Vibha Srivastava

Crop, Soil and Environmental Sciences Faculty Publications and Presentations

Post-germinative growth in plants is controlled by sucrose mobilization from the endosperm. Regulation of this process, however, is not fully understood. Transcriptional suppression of the rice vacuolar H+ translocating pyrophosphatase (V-PPase) referred to as VPP5 led to enhanced starch content in mature grains. However, vpp5 suppressed lines displayed a slower post-germinative growth rescuable by sucrose, indicating inefficient sucrose mobilization from the endosperm. Biochemical and gene expression analyses showed a slower rate of starch to sucrose conversion and altered expression of the key starch utilization pathway genes. We hypothesized that the modulation of metabolic activities in the vpp5 lines was based …

Third-Party Litigation Funding, Jonas Anderson

Utah Law Review

As the legal system confronts rising litigation costs, technological disruption, and global investment in legal claims, the discussion around TPLF is both urgent and overdue. This symposium issue provides ways to illuminate the path forward— through scholarly engagement, critical analysis, and policy innovation.

Predicting Federal Third-Party Funding Regulation, Victoria Shannon Sahani

Utah Law Review

Third-party funding is a global phenomenon, although regulatory enforcement is local. Regulatory approaches vary widely from country to country and within countries, especially in federal legal systems, such as Canada, Australia, and the United States. The United States federal government is learning about third-party funding with an eye toward potential future regulation. Congress has been investigating funding, as evidenced by testimony in congressional hearings, proposed federal legislation, and a nonpartisan study on third-party funding by the Government Accountability Office. In addition, after more than a decade of observation, the United States Federal Civil Rules Advisory Committee recently formed a committee …

Third-Party Funding Of Patent Litigation: Problems And Solutions, Korok Ray, Adam Olson

Utah Law Review

This Article documents the rise of third-party funding in patent litigation. We track funding sources for patent lawsuits in the United States from 2002 to 2021, which show an increase in cases and percentage funded by third parties. While we cannot say third-party funding increased patent litigation, we can observe the correlation. The use of the champerty doctrine by patent trolls distorts the marketplace and causes frivolous litigation.

The secondary patent market created a robust litigation market in which non-practicing entities (NPEs) can buy from innovators and sue defendants. Capital investments bet on litigation, hoping for a return without interest …

Does Third Party Litigation Funding Need Regulations On Consumer Protection, Ronen Avraham, Eric Schuller, Tony Sebok

Utah Law Review

Transcript of a roundtable discussion during the Third-Party Litigation Symposium at the S.J. Quinney College of Law

Revised Draft Final Bpsou Unreclaimed Sites: Ur-05 Remedial Action Work Plan (Rawp), Pioneer Technical Services, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Residential Factors Associated With Mental Health In United States Veterans, Air Force Military, And Air Force Employees, Andrew J. Hoisington, Christopher A. Stamper, Molly Penzenik, Meredith Reitter, Elizabeth J. Kovacs, Nazanin H. Bahraini, Lisa A. Brenner

Faculty Publications

Individuals in Westernized countries spend most of their time indoors. However, exploration of residential building factors that may influence occupants’ mental health is limited in scientific literature. The purpose of this study was to explore investigator's perceived areas of importance in residences to mental health via survey methods. To that end, we administered the Housing, Occupancy, Materials, and Environment (HOME) survey to assess factors that may influence mental health to those working in the United States (US) Air Force (n = 230) or past military members, US Veterans (n = 180). Self-reported mental health surveys were also administered to the …

War, Wounds, And Strategy: Patient Movement Lessons From The World Wars For Great Power Competition, Phillip R. Jenkins

Faculty Publications

This thesis examines the evolution of the U.S. military's patient movement system during World War I and World War II to evaluate how well it may perform under the conditions of future large-scale combat operations. It asks whether the United States can move, treat, and sustain wounded personnel at the scale and pace required to preserve combat power in a prolonged, high-intensity conflict. Using detailed case studies of the Meuse-Argonne Offensive and the Battle of the Bulge, the analysis focuses on how transportation platforms, organizational structure, and standard operating procedures (SOPs) shaped patient movement under conditions of attrition, disruption, and …

Inferring The Timing Of Antiretroviral Therapy By Zero-Inflated Random Change Point Models Using Longitudinal Data Subject To Left-Censoring, Hongbin Zhang, Mckaylee Robertson, Sarah L. Braunstein, David B. Hanna, Uriel R. Felsen, Levi Waldron, Denis Nash

Biostatistics Faculty Publications

We propose a new random change point model that utilizes routinely recorded individual-level HIV viral load data to estimate the timing of antiretroviral therapy (ART) initiation in people living with HIV. The change point distribution is assumed to follow a zero-inflated exponential distribution for the longitudinal data, which is also subject to left-censoring, and the underlying data-generating mechanism is a nonlinear mixed-effects model. We extend the Stochastic EM (StEM) algorithm by combining a Gibbs sampler with a Metropolis–Hastings sampling. We apply the method to real HIV data to infer the timing of ART initiation since diagnosis. Additionally, we conduct simulation …

The Positive Association Of Physical Activity On Sadness And Suicide Behaviors For Youth Who Have Been Bullied, Katelon Kerns, Kahir Jawad, Yana Feygin, V. Faye Jones, W. David Lohr, Jennifer Le, Kiana Fields, Jennifer Porter, Sarah Ouellette, Theresa Kluthe, Deborah Winders Davis

Biostatistics Faculty Publications

Background: Youth mental health is a public health crisis. Bullying has been associated with adverse mental health outcomes including depression and suicidal ideation. We aimed to update information regarding the associations between bullying and sadness and three suicide-related outcomes, along with the potential moderating effect of physical activity (PA). Methods: Using the 2017–2021 Youth Risk Behavior Surveillance System (YRBSS) with students in grades 9–12 we used descriptive statistics, chi-square tests, and multivariable logistic regressions to examine the association between students who have been bullied and who reported feeling sad or hopeless, as well as considered, planned, and/or attempted suicide, within …

Late-Nc Stage 3, Ryan K. Shahidehpour, Yuriko Katsumata, Dennis W. Dickson, Nikhil B. Ghayal, Khine Zin Aung, Xian Wu, Panhavuth Phe, Gregory A. Jicha, Allison M. Neltner, Jessalin R.C. Archer, Maria M. Corrada, Claudia H. Kawas, S. Ahmad Sajjadi, Davis C. Woodworth, Syed A. Bukhari, Thomas J. Montine, David W. Fardo, Peter T. Nelson

Biostatistics Faculty Publications

A diagnostic rubric is required to distinguish between limbic-predominant age-related TDP-43 encephalopathy neuropathologic change (LATE-NC) and frontotemporal lobar degeneration with TDP-43 inclusions (FTLD-TDP). In LATE-NC Stage 3, TDP-43 proteinopathy is present in the middle frontal gyrus (MFG), thus posing a potential diagnostic challenge in differentiating these severe LATE-NC cases from FTLD-TDP. LATE-NC Stage 3 cases and other TDP-43 proteinopathies were analyzed from the University of Kentucky (total n = 514 with TDP-43 pathology assessed), The 90+ Study at the University of California Irvine (n = 458), and the Mayo Clinic (n = 5067) brain banks. Digital pathology was used to …

Genetic Control Of Prickles In Tetraploid Blackberry, Carmen Johns, Alexander Silva, Thomas Mason Chizk, Lacy Nelson, John R. Clark, Rishi Aryal, H. Ashrafi, Ellen Thompson, Michael Hardigan, Margaret Worthington

Horticulture Faculty Publications and Presentations

Prickle-free blackberry (Rubus subgenus Rubus) canes are strongly preferred by growers due to food and worker safety concerns and damage to fruit from mechanical injury by prickles. This project was conducted to identify the genetic region responsible for prickle-free canes derived from the recessive "Merton Thornless" source in autotetraploid blackberry using a genome-wide association study, develop diagnostic Kompetitive Allele-Specific PCR markers for prickle-free canes, and determine the effects of allele dosage at the prickle-free locus on prickle density in 2 biparental populations. The prickle locus was located on chromosome Ra04 from 30.48 to 36.04 Mb in an extensive LD block, …

A Realizability Approach To Constructing Higher Types Via Classifiers, Benjamin Carrick Logsdon

Dartmouth College Ph.D Dissertations

We construct an interpretation of higher types into Peano arithmetic, showing in particular that every model of PA is a model of higher types. This is a reversal of Gödel’s Dialectica construction. We also define the classifier degrees, a degree structure which subsumes the Turing degrees, the enumeration degrees, and the many-one degrees. The classifier degrees boast a rich structure and many well-behaved operations.

Epidemiology Of Hip Dislocations In The United States From 1990 To 2019: A Temporal Study Using The Global Burden Of Disease Database., Ambrose Loc T Ngo, Gabrielle Dykhouse, Taylor J Manes, Phillip C Mckegg, Cameron J Sabet, Brett Barthman, Robert Golden

Trauma and Acute Care Articles

Introduction Hip dislocations are devastating injuries that require urgent intervention to minimize the development of severe complications. This study aimed to evaluate the epidemiology of hip dislocations in the United States (U.S.) from 1990 to 2019. Methods This study is a descriptive retrospective epidemiological study. The Global Burden of Disease (GBD) database was used to collect epidemiological data on hip dislocation in the U.S. from 1990 to 2019. Data included years lived with disability (YLDs), prevalence, and incidence rates per 100,000 people. Data were regionally stratified into Northeast, Midwest, South, and West by the U.S. Census definition. Bartlett's test was …

Red Sea Task Force: Assessing The Legal Implications Of The Military Response To Houthi Attacks In The Red Sea, Case Western Reserve University School Of Law

Yemen Accountability Project (YAP)

No abstract provided.

Power Transmission System Demo, Jeremy Aiken, Shannon Robinson, Graham Dzengelewski

Mechanical Engineering

Professor Ramanan Sritharan and ME 329 students need a high-quality Power Transmission System, a detailed report, and robust Excel spreadsheet including all calculations that can serve as an example for students in the ME 329 lab.

Integrating Social Emotional Learning, Mindfulness, And Nutrition Education Into Curricula To Promote Self-Regulation And Healthy Eating Behaviors Among Preschoolers, Rachel A. Razza, Lynn Brann

The Lender Center for Social Justice

This article outlines a combined SEL, mindfulness, and nutrition curriculum for preschoolers, improving self-regulation and healthy eating habits.

Foot Pedal Assistive Device, Julian Rubinstein, Connor Jessen, Isabelle Utsler, Sydney Alexander

Mechanical Engineering

Individuals with lower-limb mobility problems may have trouble accurately locating the pedals of a three-pedal manual transmission car, and some medical conditions cause individuals to fatigue more quickly when driving. This project aimed to create a device that assists in locating the user’s feet, indicates to the user which pedals are currently in use, and provides a visual and physical warning if they are not in the correct place. The project sponsor, Alan Keizer, is the primary stakeholder in this project. This device will be designed specifically for Alan’s Subaru BRZ and will address Alan’s specific lower-limb mobility issues that …

Van Accessibility, Ann Larson, Camelia Anne Noureddine, Stephanie Rose Ruzicka, Kayla Joanne Gowey

Mechanical Engineering

The SLO Achievement House provides resources and activities for their clients, including daily trips to different parts of the community, to keep their clients connected to society. These trips require the clients, many of whom struggle with general mobility and strength, to step up to the high entrance of a van or company car. This daily activity poses a challenge both physically and emotionally for the clients. The current solution utilizes commercially available step stools, which lack handrails, overall stability, and adequate step depth. The Achievement House needs a stool or ramp tailored to their client’s needs and their specific …

7lr-C Upper Limb Dancing Prosthetic, Victor Ochoa, Zoe Kelemen, Ged Mulingtapang, Marley Paltiel

Mechanical Engineering

Ella Wallis, a student at Cal Poly and performer in the Cal Poly Drag Club with a trans humeral upper limb difference, wants a prosthetic device that allows for a large range of motion and high degree of articulation to help them better dance in the style of voguing, allowing them to express themselves further while performing. The prosthetic arm is body-driven and relies on momentum to reposition. It attaches to the user through a harness, which is clipped to a socket with elastic straps to not impede the shoulder’s range of motion. The design contains urethane resin, aluminum, stainless …

Drone Package Delivery System, Aiden Tyler Sim, Ryan Anders O'Toole, Matthew Karl Wyant, James Shaw Glanville

Mechanical Engineering

In response to the demands of the 2025 C-UASC (California Unmanned Aerial Systems Competition), our team developed an autonomous drone payload delivery system capable of two distinct delivery modes: a precision-controlled descent and a high-speed aerial drop. Designed for modular integration with UAV platforms, the system prioritizes reliability, accuracy, and simplicity under desert environmental conditions. Our solution features a custom winch mechanism with a programmable stepper motor, a passive mechanical hook for tension-based release, and a servo-actuated trapdoor for high-altitude drops. The design was extensively tested for structural integrity, motor torque requirements, drop precision, and electronics reliability—culminating in a robust …