Digital Commons Network^™

Voluntary Contractions Underestimate Peak Muscle Activity In Drop Jumps, David Alan Phillips, Skylar Paletta, Michael R. Perlet

Department of Kinesiology Scholarship and Creative Works

Maximal voluntary isometric contractions (MVIC) are a common method to normalize electromyographic amplitude into standardized units of %MVIC. However, in 60% of drop jump research using an MVIC in 2018–2023, supramaximal activation or activation greater than 100% MVIC occurred. Therefore, MVICs may not be representative of peak muscle activation, leading to erroneous interpretation of muscle activation. The purpose of this study is to quantify EMG normalization difference in drop jump landings. Sixteen (10 M, 6F) participants were recruited for the study. MVICs were recorded from nine lower extremity muscles and this activation compared to the maximal activation recorded from 10 …

Sea Cucumbers Could Hold Key To Stopping Cancer Spread, Clara Turnage

University of Mississippi News

OXFORD, Miss. – Sea cucumbers are the ocean's janitors, cleaning the seabed and recycling nutrients back into the water. But this humble marine invertebrate could also hold the key to stopping the spread of cancer.

A Provably Secure Coercion-Resistant E-Voting Scheme With Confidentiality, Anonymity, Unforgeability, And Cai Verifiability, Yun Xing Kho, Swee Huay Heng, Syh Yuan Tan, Ji Jian Chin

School of Engineering, Computing and Mathematics

Ensuring both cast-as-intended (CAI) verifiability and coercion-resistance in e-voting remains a critical challenge. The e-voting scheme proposed by Finogina and Herranz in 2023 represents the first notable advancement in reconciling these conflicting requirements. CAI verifiability allows voters to confirm that their intended vote has been correctly recorded, even without a secure channel to the election committee, while coercion-resistance prevents external influence and vote-selling. However, essential security properties such as confidentiality, anonymity, unforgeability, and double-voting prevention fall outside the scope of Finogina and Herranz’s e-voting scheme, leaving significant gaps in its security guarantees. To address this limitation, we propose a novel …

Revised Unsteady Drag Force And Its Impact On Particle Dynamics At High Reynolds Numbers, Ahmad Talaei, Timothy J. Garrett

Physics Student Research

The accurate modeling of particle motion in viscous fluids at high Reynolds numbers remains a fundamental challenge, particularly under unsteady flow conditions where nonlinear effects dominate. This study introduces a revised unsteady drag formulation, extending its applicability beyond previous studies. By integrating classical solutions of the Navier–Stokes equations, the new formulation overcomes the limitations of the Maxey–Riley–Gatignol (MRG) equation, addressing non-physical memory effects associated with Basset drag and extending its applicability to higher Reynolds numbers.

Through experimental comparisons and direct numerical simulations (DNS), the revised equation of motion is compared to the MRG equation, both during steady-state conditions and non-equilibrium …

Santa Clara Radio Astronomy Project Iv: Data Acquisition, Nicholas Alva, Peter Lattimer

Electrical and Computer Engineering Senior Theses

Santa Clara Radio Astronomy Project (SCRAP) is a multi-year project that aims to make radio astronomy accessible to the Santa Clara University community. Previous iterations have focused on constructing and improving a parabolic radio telescope located on the balcony of the fourth floor at The Sobrato Campus for Discovery and Innovation at Santa Clara University. Until this year, the radio telescope has been stationary. As a consequence, the telescope is only capable of observing celestial objects directly above it, severely limiting the data capture area. This thesis describes the contributions of SCRAP IV Data Acquisition to the project: enabling 2D …

Critical Race Theory And Higher Education In Ireland: An Exploration Of The Experiences Of Black Minority Ethnic Social Care Students, Margaret Fingleton

Irish Journal of Academic Practice

This paper examines the experiences of Black Minority Ethnic students studying in higher education in Ireland, contextualizing them by key global events that occurred over the last decade. The research was underpinned by the core principles of Critical Race Theory (CRT) with a particular focus on the tenets of storytelling and intersectionality. Based on a qualitative approach, a participatory research methodology informed all phases of the study. Using a combined semi-structured interview/storytelling method, twenty-one female social care students in five higher education institutions participated in the study. In collaboration with a participatory advisory group, reflective thematic analysis was utilised to …

Couples And Pornography: A Dyadic Latent Profile Analysis Of Romantic Partners And Pornography Use, Michelle E. Haddock Edwards

Theses and Dissertations

Research on the outcomes of pornography use for romantic couples has been extensive yet inconclusive. Studies have examined pornography use in a wide variety of contexts, leading to a wide variety of outcomes and well-being. The current study uses latent profile analysis to account for many contextual factors at once, dyadic data to examine the perspective of both partners simultaneously, and a range of individual and relational well-being outcomes to understand how different relational pornography use patterns lead to well-being. Results provided evidence for six unique profiles of couples based on pornography use patterns (personal use frequency, perceived partner use …

Risky Business: Organizational Challenges In International Support For Civilian Self-Protection, J. M. Welsh, Emily Paddon Rhoads, J. Masullo

Political Science Faculty Works

Over the last decade, a range of international actors has moved away from direct forms of intervention to protect civilian populations in favor of “bottom-up” approaches that emphasize external support for civilian self-protection (CSP). While this indirect action is often perceived to be less costly, more legitimate, and potentially more effective, we argue that external support for CSP is a “risky business” that presents a significant dilemma for international governmental and nongovernmental organizations. Drawing on literature from sociology, economics, and civil war studies, we conceptualize and categorize the risks of unintended consequences that could accompany external support for CSP and …

Selective Anti-Tumor And Normal Tissue Sparing Effects Of Flash Radiotherapy In A Simple Algebraic Model Of Radiochemical Kinetics, Charles F. Babbs

Weldon School of Biomedical Engineering Faculty Working Papers

Background: This short paper presents the solution to an open problem in medical physics: how and when FLASH radiotherapy can have a selective anti-tumor effect. FLASH radiotherapy gives a single large dose of ionizing radiation to a cancer patient within a time span of a few milliseconds, unlike conventional radiotherapy which is divided into several dose fractions given weekly, each lasting about 10 minutes. In some animal models FLASH seems to improve tumor cell killing without damaging normal tissues. However, the mechanism of the selective anti-tumor effect remains elusive. Methods: To explore effects of tissue hypoxia in tumors, a model …

Competition In The Global Law Market: Offshore Development Of The Statutory "Rule In Hastings-Bass", Andrew P. Morriss

Minnesota Journal of International Law, Vols. 28:2 onward (2019-present)

This Article examines the competitive dynamics in the global law market through the lens of the statutory evolution of the Rule in Hastings-Bass across various International Financial Centers (IFCs). Following the UK Supreme Court’s 2013 decision in Pitt v Holt and Futter v Futter, which significantly restricted the judiciary’s ability to void trustee decisions under the Rule, seven IFCs (Jersey, Bermuda, The Bahamas, the Dubai International Financial Center, the Cayman Islands, and the British Virgin Islands) enacted statutes to preserve and clarify the Rule within their jurisdictions. These legislative actions highlight the strategic adaptations by IFCs to enhance their legal …

Human Rights And Foreign Policy: South Africa's Genocide Complaint Against Israel At The International Court Of Justice, Penelope Andrews

Minnesota Journal of International Law, Vols. 28:2 onward (2019-present)

No abstract provided.

International Abolitionist Advocacy: The Rise Of Global Networks To Advance Human Rights And The Promise Of The Worldwise Campaign To Abolish Capital Punishment, John D. Bessler

Minnesota Journal of International Law, Vols. 28:2 onward (2019-present)

The modern international human rights movement began with the U.N. Charter and the U.N. General Assembly’s adoption of the Universal Declaration of Human Rights. Although the movement to abolish the death penalty is rooted in the Enlightenment, global advocacy to halt executions and to abolish capital punishment has accelerated exponentially in recent decades. This Article discusses the origins of global networks to advance human rights and highlights the growing international advocacy, including by nation-states and nongovernmental organizations (“NGOs”), for a worldwide moratorium on executions and to abolish capital punishment altogether. The total number of countries conducting executions in the past …

Establishing A "Duty To Not Destroy": Using Fiduciary Duty To Hold Settler-Colonial States Responsible For Cultural And Linguistic Harms Committed Against Indigenous Students At Government-Run Boarding Schools, Kristina Mclaughlin

Minnesota Journal of International Law, Vols. 28:2 onward (2019-present)

No abstract provided.

Revival Of Industrial Policy Implications For International Trade Law, Yong-Shik Lee

Minnesota Journal of International Law, Vols. 28:2 onward (2019-present)

In recent years, the world’s major economies, such as the United States, China, and the European Union, have adopted policies that aim to promote domestic industries in strategic areas, such as semiconductors and electric vehicles, through substantial subsidization. These policies have been justified for the need to secure supply chains and protect national security interests, but they are also incompatible with the rules of international trade law, such as the WTO Subsidies and Countervailing Measures Agreement. There are considerable challenges to addressing this incompatibility as these economies have shared interests in promoting these policies for their own domestic industries. The …

And They Would Have Gotten Away With It, If Not For Those Meddling Federales: Examining State Responses To Transnational Organized Crime And Developing A Policy Framework, Aaron Lutz

Minnesota Journal of International Law, Vols. 28:2 onward (2019-present)

Transnational criminal organizations (TCOs) have begun expanding their enterprise into criminal gold mining in South America. This is causing widespread harm from human trafficking, pollution, and disease. These groups exploit vulnerable artisanal miners (ASMs) to provide a foothold in the gold mining industry and avoid the reach of states. This note examines the policy responses that South American countries have taken to this phenomenon and develops a policy framework for state actors moving against TCOs.

The End Of The Khmer Rouge Tribunal: Its Success And Legacy, Choongman Lee

Minnesota Journal of International Law, Vols. 28:2 onward (2019-present)

This note critically examines the effectiveness of the Extraordinary Chambers in the Courts of Cambodia (“ECCC”), in achieving justice against members of the Democratic Kampuchea, also known as the Khmer Rouge, and explores areas where the ECCC could influence international criminal law in the future. The analysis explores the structural flaws, political interference, and challenges faced by the ECCC, particularly in Cases 003 and 004. Despite these challenges, the court successfully convicted three individuals in Cases 001 and 002, providing a degree of justice for victims. Also, the ECCC’s unique features, such as the super-majority rule, victim-centered approach, and residual …

Potentials Of Informal Household-Practiced Urban Farming As A Contributor To Sustainability And Resilience In Emirati Neighbourhoods, Hadia Al Haddad

Thesis/ Dissertation Defenses

The United Arab Emirates (UAE) has integrated local agendas aimed at achieving urban sustainability and resilience, particularly in alignment with UAE Vision 2030. However, official initiatives in this domain often lack genuine community participation—a critical pillar for the success of sustainable urban development. Meanwhile, urban farming has garnered increasing recognition both globally and locally as a significant contributor to urban sustainability and resilience. In the UAE, official focus has largely centered on professional vertical farming, demonstrated through various high-profile projects. In contrast, informal, household-based urban farming is actively practiced within semi-public, semi-private, and private spaces across many Emirati public housing …

Influence Of Filler Content And Polishing On Candida And Streptococci Biofilm Formation In Resin-Based Composites: An In Vitro Evaluation, Zahra Zareshahrabadi, Sarina Sahmeddini, Marzieh Meimandinezhad, Afsoon Tondari, Kamiar Zomorodian

Pacific Faculty Work

Aim: The purpose of this study was to investigate the impact of filler content and polishing of resin-based composites on in vitro biofilm formation of Candida and Streptococci species. Materials and Methods: Specimens of four commercially available resin-based composites including Z100, P60, Z250, and Z350, with different filler amounts and volumes, were prepared according to the manufacturer’s instructions. Each group was divided into polished and unpolished specimens, which were then placed in a 24-well tissue culture plate with microbial suspension and incubated. The XTT technique was used to evaluate biofilm formation. Results: Z250 resin-based composites, which had the highest percentage …

Econ100 Economics And Society Course -- Queens College, Clive Belfield

Open Educational Resources

This is a syllabus for a contemporary course on Economics for students with no background in Economics. The course blends theory and up-to-date evidence.

Community Perspectives On Cancer And Cancer Research: Findings From Listening Sessions With Diverse Groups In Philadelphia, Karen Glanz, Emma A. Soliva, Krista Scheffey, Yawei Song, Charnita Zeigler-Johnson, Evelyn T. González, Thierry Fortune, Nilsa Graciani, Amy E. Leader

Kimmel Cancer Center Faculty Papers

BACKGROUND: Listening sessions are useful for understanding community perspectives on cancer disparities. The Philadelphia Communities Conquering Cancer (PC3) coalition conducted listening sessions to identify community priorities for cancer prevention and control research among diverse communities in Philadelphia.

METHODS: Guided by a Stakeholder Advisory Committee, PC3 partnered with community-based organizations to conduct 8 listening sessions with diverse communities (including Black, Hispanic, Asian, Russian, LGBTQ + , and veterans) to learn about perceptions of cancer, research priorities, and training and communication preferences. Sessions were facilitated by community members or PC3 members in the primary language of participants. Sessions were audio recorded, transcribed, …

Paul College Student Surprised With ‘Full Ride’ Scholarship, Michelle Morrissey

UNH Today Archive

No abstract provided.

A Forward Genetic Screen Identifies Potassium Channel Essentiality In Shh Medulloblastoma Maintenance, Jerry J Fan, Anders W Erickson, Julia Carrillo-Garcia, Xin Wang, Patryk Skowron, Xian Wang, Xin Chen, Guanqiao Shan, Wenkun Dou, Shahrzad Bahrampour, Yi Xiong, Weifan Dong, Namal Abeysundara, Michelle A Francisco, Ronwell J Pusong, Wei Wang, Miranda Li, Elliot Ying, Raúl A Suárez, Hamza Farooq, Borja L Holgado, Xiaochong Wu, Craig Daniels, Adam J Dupuy, Juan Cadiñanos, Allan Bradley, Anindya Bagchi, Branden S Moriarity, David A Largaespada, A Sorana Morrissy, Vijay Ramaswamy, Stephen C Mack, Livia Garzia, Peter B Dirks, Xuejun Li, Siyi Wanggou, Sean Egan, Yu Sun, Michael D Taylor, Xi Huang

Faculty, Staff and Students Publications

Distinguishing tumor maintenance genes from initiation, progression, and passenger genes is critical for developing effective therapies. We employed a functional genomic approach using the Lazy Piggy transposon to identify tumor maintenance genes in vivo, and applied this to SHH medulloblastoma (MB). Combining Lazy Piggy screening in mice and transcriptomic profiling of human MB, we identified the voltage-gated potassium channel KCNB2 as a candidate maintenance driver. KCNB2 governs cell volume of MB-propagating cells, with KCNB2 depletion causing osmotic swelling, decreased plasma membrane tension, and elevated endocytic internalization of EGFR, thereby mitigating proliferation of MB-propagating cells to ultimately impair MB growth. …

Regulation Of Myogenesis By Mechanomir-200c/Foxo3 Axis, Junaith S Mohamed, Aladin M Boriek

Faculty, Staff and Students Publications

Cyclic mechanical stretch has been shown to inhibit myoblast differentiation while promoting proliferation. However, the underlying molecular mechanisms are not well understood. Here, we report that mechanical stretch inhibits the differentiation of mouse primary myoblasts by promoting the cell cycle program and by inhibiting the expression of the myogenic regulator MyoD. Stretch alters the miRNA expression profile as evidenced by miRNA microarray analysis. We identified miR-200c as one of the highly downregulated mechanosensitive miRNAs (mechanomiRs) whose expression level was increased during differentiation. This suggests that mechanomiRs-200c is a myogenic miRNA. Overexpression of mechanomiR-200c revoked the effect of stretch on myoblast …

Cannabis Concentrate Vaping Chemistry, Kaelas R. Munger, Killian M. Anreise, Robert M. Strongin

Chemistry Faculty Publications and Presentations

Background:

This review article addresses the vaping chemistry of manufactured cannabis concentrates—a topic that remains under-researched despite the widespread availability and growing popularity of these products. Given their current prevalence and the fact that many of the findings discussed herein are from early-stage investigations, further research is essential to fully assess the public health risks associated with concentrate use. The purpose of this article is to help begin to bridge this knowledge gap by outlining the technical challenges of studying cannabis concentrates and to present evidence-based data concerning toxicant exposures as a foundation for future investigations.

Methods:

A search of …

Identifying The Drivers Behind The Decline Of Douglas-Fir And True Fir Species In Sw Oregon, Alexander Bryant Bentley

Dissertations and Theses

Increased levels of Pseudotsuga menziesii (DF) and Abies species (TF) decline throughout dry forests in the Klamath Mountains and Western Cascades ecoregions have been recorded in recent years, with preliminary evidence suggesting that factors influenced by changing climatic conditions and encroachment from fire suppression policies are primarily to blame. Yet, the physiological and environmental mechanisms of drought-driven tree decline are poorly understood across biophysical and spatial gradients. Given the complex relations that drive decline, determining the degree of influence of specific drivers is difficult, creating unique challenges for modern forest management. To elucidate the most important factors driving DF and …

Support Beyond Services: Examining The Role Of Neighbor Relationships, Housing Staff, And Place In Mental Health Recovery, Kenna Estell Dickard

Dissertations and Theses

This dissertation explores the role of non-clinical support for individuals with serious mental illness (SMI). Through three interconnected manuscripts, this dissertation highlights the importance of housing staff support, places in the community, and neighbor relationships in fostering recovery for individuals with SMI. The first manuscript analyzes how housing staff support influences residents' well-being through an ecological lens. This study found that staff support is associated with reduced loneliness, higher residential satisfaction, and increased sense of community. This study also considers the role of self-determination as a moderator, demonstrating the importance of resident agency in maximizing well-being outcomes. The second manuscript …

Lrrc8 Channel Complexes Counterbalance Katp Channels To Mediate Swell-Secretion Coupling In Mouse Pancreatic Β Cells, Tarek Mohamed Abd El-Aziz, Chen Kang, Litao Xie, John D. Tranter, Sumit Patel, Rahul Chadda, Maria S. Remedi, Rajan Sah

2020-Current year OA Pubs

Insulin secretion from pancreatic β cells is initiated by membrane potential depolarization, followed by activation of voltage-gated Ca2+ channels to trigger Ca2+-mediated insulin vesicle fusion with the β cell plasma membrane. Here, we show that β cell swelling associated with glucose metabolism was sensed by LRRC8 channel complexes and contributed to insulin secretion. Hypertonic perfusate (360-380 mOsm) dose dependently impaired glucose-stimulated insulin secretion by counteracting β cell swelling. Hypotonic perfusate alone, independent of glucose stimulation or KATP channel closure, was sufficient to increase β cell intracellular Ca2+ and trigger insulin secretion. Inhibition of sodium-potassium-chloride cotransporter-1 with bumetanide, which diminished the …

Determining Accurate Pore Structures Of Polypropylene Membrane For Ecmo Using Fe-Sem Under Optimized Conditions, Makoto Fukuda, Yoshiaki Nishite, Eri Murata, Koki Namekawa, Tomohiro Mori, Tsutomu Tanaka, Kiyotaka Sakai

Children’s Nutrition Research Center Staff Publications

Long-term ECMOs are expected to be put into practical use in order to prepare for the next emerging severe infectious diseases after the novel coronavirus pandemic in 2019-2023. While polypropylene (PP) and polymethylpentene (PMP) are currently the mainstream materials for the hollow fiber membranes of ECMO, the PP membrane coated with a silicone layer on the outer surface has also been commercialized. In this study, we sought a method to accurately observe the detailed pore morphologies of the PP membrane by suppressing irreversible changes in the morphology in SEM observation, which is a general-purpose observation with higher resolution. As a …

Draft Final 2025 Residential Metals Abatement Program (Rmap) Quality Assurance Project Plan (Qapp) Annual Update (Residential Parcels), Pioneer Technical Services, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Longitudinal Plasma Amino Acids During Pregnancy And Neonatal Anthropometry: Findings From The Nichd Fetal Growth Studies-Singleton Cohort, Claire Guivarch, Jing Wu, Ruijin Lu, Jagteshwar Grewal, Guoqi Yu, Ling-Jun Li, Jiaxi Yang, Wei Wei Pang, Dong D Wang, Natalie L Weir, Zhen Chen, Michael Y Tsai, Cuilin Zhang

2020-Current year OA Pubs

BACKGROUND: Amino acids (AAs) during pregnancy are crucial for fetal growth. Prior studies measured AA concentrations at single time points in pregnancy, despite their fluctuations throughout pregnancy. We measured plasma AA profiles in blood samples longitudinally collected from early through late pregnancy and evaluated their associations with neonatal anthropometry.

METHODS: Concentrations of plasma aromatic AAs, branched-chain AAs, and AAs involved in one-carbon metabolism were assessed at 10-14, 15-26, 23-31, and 33-39 gestational weeks (GW) among 321 women from a case-control study from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Fetal Growth Studies-Singleton Cohort. Associations …