Digital Commons Network^™

Camping And Pass Order Form, Extension

UNH Cooperative Extension

No abstract provided.

Fairentry Registration Help Sheet, Extension

UNH Cooperative Extension

No abstract provided.

Pd Chlorin-Based Molecμlar Imaging Probes For Breast Cancer, Yoonjung Cho

Theses

Breast cancer (BrCa) is the second most common cancer and the second leading cause of cancer death among women in the U.S. This highlights the necessity of developing effective therapeutic agents to aid in the treatment of BrCa. A promising new method of treatment is photodynamic therapy (PDT), a clinically approved therapeutic procedure that uses a porphyrin-based photosensitizer (PS) dye to kill cancer cells upon excitation with a light source. It has been observed that chelation of a metal ion into the porphyrin increases the therapeutic efficacy. We have developed a synthetic route incorporating the palladized analogue of the PS …

Product, Process, And Behavior Influences On Value Retention Processes: Toward A Circular Economy In Consumer Electronics, Kyle Parnell

Theses

Consumer electronic products (CEP) manufacturing and retail contribute markedly to global industrial activity; worldwide estimates suggest revenue growth from $1 trillion in 2020 to $1.5 trillion by 2026. Consequently, the production, distribution, use, and end-of-life (EOL) disposition of these products are responsible for considerable social and environmental impacts, including 35 million metric tonnes of waste to landfill per year, 793 million metric tonnes (MMT)—and growing—of carbon dioxide-equivalent (CO2e) greenhouse gas (GHG) emissions per year, and innumerable adverse effects on human health and development. Driving these impacts are the inherent characteristics of CEPs themselves, which increasingly require critical materials in design, …

Ambient Environment Effect On Color Perception, Eddie Pei

Theses

The ambient environment—including both background and surround conditions—is a critical factor influencing color perception. It affects not only how we perceive colors but also how we interpret complex visual scenes, impacting both sensory processing and cognitive interpretation. This thesis focuses on three major perceptual phenomena: simultaneous contrast, mixed chromatic adaptation, and color preference. First, the effects of simultaneous contrast on hue, chroma, and lightness in traditional displays were explored. This study was extended to a dual-display augmented reality (AR) environment that introduces layered perception. An extension to the CIECAM16 color appearance model is proposed to incorporate this effect. Second, the …

Advancing The Utility Of Unmanned Aerial Systems (Uas)-Based Imaging Techniques In Broadacre Agriculture: A Multimodal Case Study On Table Beets, Mohammad Shahriar Saif

Theses

Efficient and sustainable food production and management are growing concerns in the context of an ever-increasing global population. It is in this context that the integration of remote sensing with advanced imaging technologies presents transformative opportunities for data-driven decision-making in agriculture. This study therefore explores the use of unmanned aerial systems (UAS) equipped with multispectral, hyperspectral, and LiDAR sensors for the non-destructive monitoring of table beet (Beta vulgaris) crop traits, with a specific focus on root yield estimation and foliar disease assessment. Table beet, a subterranean crop of increasing commercial and nutritional importance, poses unique challenges for above-canopy sensing due …

Analytics Of Capstone Projects: Understanding Outcomes Through People, Products, And Processes, Hrushikesh C. Godbole

Theses

The capstone project is a bridge from the university to industry. During the project, students not only learn the process of integrating previously learned engineering concepts into an actual product but also practice essential professional skills such as communication, teamwork, and project delivery. How can universities ensure effective capstone student learning and good outcomes? To answer this question, the capstone project is studied as a system comprising of products, people, and processes. People refer to the students and instructors involved. Students develop products by following development processes. Instructors guide students using instruction processes. In educational context there limited control over …

Using Probabilistic Component Separation To Measure The Sunyaev-Zel’Dovich Effect In Herschel-Spire Galaxy Cluster Observations, Daniel Jeremy Klyde

Theses

Galaxy clusters evolve over cosmic history from small gravitational over-densities at redshift z > 7 to become the most massive gravitationally bound objects in the universe today. The demographics of galaxies populating clusters have shifted significantly over this time, from sites of intense star formation at z ~ 2-4, to largely quiescent objects in the current epoch. An important phase of this evolution involves the development of a hot, ionized intracluster medium (ICM). Its formation around cosmic noon overlaps with the peak in star formation, which requires a multi-wavelength observational approach to fully characterize. One way to study the properties of …

Predicting Hollywood Movie Success Using Predictive Machine Learning Algorithms, Saeed Alghabshi Hathboor

Theses

The Decision Trees are always simple to understand and interpret techniques, a single tree may not be enough for the model to learn the characteristics from. In this IMDb movie review prediction problem, evading all other simple mechanisms, the Random Forest, on the other hand, is a "Tree"-based algorithm that makes judgments by combining the attributes of numerous Decision Trees is used. The primary goal of this work is to evaluate the predictive performance of a random forest model with various parameters used for forecasting numerical user ratings of a movie based on pre-release data such as actors, directors, profit, …

Opportunities For Mathematical Thinking (Omt) In Fourth Grade Mathematics Textbooks., Lucas Wayne Elliott

Electronic Theses and Dissertations

Mathematical thinking is essential not only for students’ academic achievement but also for their ability to compete in a global workforce (Schoenfeld, 1992; Mullis & Martin, 2017). However, students in the United States continue to lag behind their international peers on assessments that measure mathematical thinking (Mullis et al., 2020; van Davier et al., 2024). These gaps emerge as early as elementary school, where the foundation for future academic success is established (Aunola et al., 2004; Locuniak & Jordan, 2008). Given the importance of mathematical thinking and the persistent disparities in student performance, this study examined how mathematical thinking is …

A Deep Learning Approach For Semantic Segmentation And Its Application On Ctc., Samir Farag Harb

Electronic Theses and Dissertations

This dissertation explores the modeling and analysis of medical images, focusing on the intricate task of colon segmentation and subsequent 3D reconstruction, which are critical steps in Computed Tomography Colonography (CTC) systems. The primary objective of this research is to develop precise segmentation approaches to enhance the accuracy of colon identification and reconstruction from abdominal CT scans. Three distinct segmentation approaches are proposed and evaluated: a Markov Random Field (MRF)-based approach, a convolutional neural network (CNN)-based deep learning (DL) approach, and a sequential episodic training with dual contrastive learning Approach (G-SET-DCL) that has a flavor of few-shot learning (FSL). To …

Immunopathogenic Crosstalk Between Cancer And The Kidney: A Central Role For Macrophages As Potential Mediators., Dana Hammouri

Electronic Theses and Dissertations

Cisplatin remains a mainstay in the treatment of solid tumors, yet its therapeutic efficacy is frequently compromised by dose-limiting nephrotoxicity. Approximately 30% of patients receiving cisplatin develop acute kidney injury (AKI), which increases the risk of chronic kidney disease (CKD), a leading cause of morbidity and mortality. Despite extensive preclinical efforts, no FDA-approved therapy currently exists to prevent or treat cisplatin-induced nephrotoxicity (CIN). This in part is due to the reliance of preclinical studies on non-cancer animal models that fail to capture the complex physiological alterations associated with malignancy. To address this limitation, we developed a clinically relevant model in …

Estimation Methods For Bayesian Exponential Random Graph Models Under The Horseshoe Prior., Pamela Linares

Electronic Theses and Dissertations

Networks are powerful tools for modeling the complexity of social interactions, biological systems, and information spread. A leading statistical frameworks for analyzing network data are Exponential Random Graph Models (ERGMs), which provide a principled approach to capturing structural dependencies. However, ERGMs remain challenging to estimate, especially in sparse or high-dimensional settings where models suffer from degeneracy and unstable parameter inference. This paper proposes a penalized Bayesian approach to ERGMs that utilizes the horseshoe prior, a sparsity-inducing global-local shrinkage prior. This prior offers robust regularization while preserving important signals, improving estimation by shrinking irrelevant parameters and reducing the impact of extreme …

Beyond The Individual: A Dyadic Mixed-Methods Study Of Work–Life Balance In Entrepreneurial Households., Juliana Binhote

Electronic Theses and Dissertations

Entrepreneurs operate at the intersection of work and family systems; yet, their experiences with work–life balance (WLB) remain underexplored—particularly in relational contexts. While existing research highlights the psychological demands of entrepreneurship, it often overlooks how family dynamics shape entrepreneurs’ experiences of balance, conflict, and boundary management. Guided by boundary theory, conservation of resources theory, and the goal attainment balance model, this dissertation investigates the question: How do entrepreneurs experience and make sense of their work-life balance? To answer this question, I designed a dyadic exploratory mixed-methods study. In Study 1, I conducted in-depth interviews with family business entrepreneurs and their …

Taming The Wild Tongue Of Frida Kahlo: An Analysis Of Translation As Adaptation In Personal Narratives, Alyse K. Deatherage

Electronic Theses, Projects, and Dissertations

This thesis discusses topics of adaptation and translation theory by looking at the way Frida Kahlo’s diary has been transformed through both adaptation and translations of it in the texts The Diary of Frida Kahlo: An Intimate Self-Portrait and The Diary of Frida Kahlo: A New Perspective. Scholars have paid much attention to the connections between Kahlo’s diary and her portraits, focusing on artistic critique and the painter’s diary as a drafting space for what eventually became her famous self-portraits. Researchers have also documented Frida Kahlo’s artistic and cultural influences in Mexico and abroad. However, none have addressed the …

Bilingual Budget-Friendly Hispanic Cookbook And Resource Guide For Food Pantries In San Bernardino County, Anasofia Garay Guzman

Electronic Theses, Projects, and Dissertations

San Bernardino County is faced with a significant issue of food insecurity with its residents relying on food pantries to meet their food and nutritional needs. However, the food items offered at food pantries are often limited in quantities and the variety is inconsistent, which makes it a challenge for families wanting to prepare healthier budget friendly meals while maintaining its cultural relevance. This project consists of two main key components: a bilingual, culturally relevant budget-friendly Hispanic cookbook and a comprehensive resource guide about ways and ingredient substitutions adaptable to the recipe based on what is available.

The cookbook included …

Impact Of S-Phase Kinase Protien 2 Blockades On Hematopoetic Stem Cell Metabolism, Nicole Elmaraghy

Electronic Theses, Projects, and Dissertations

Hematopoietic stem and progenitor cells (HSPCs) quiescence is vital for the success of bone marrow transplantation, as it preserves long term self- renewal and prevents premature exhaustion (Takubo et al., 2013; Wilson et al., 2008). However, bone marrow transplant (BMT) failure remains a clinical challenge, often due to lack of long-term engraftment and insufficient stress reliance. Both of these characteristics are tightly linked to disrupted stem cell quiescence and metabolic imbalance (Anso et al., 2017; Vannini et al., 2016). One key player is S-phase kinase protein (SKP2), an E3 ubiquitin ligase that targets cell cycle inhibitors, like p27, for proteosome …

Knowledge And Perceptions Of Prebiotics And Probiotics Among University Students, Itzel Martinez

Electronic Theses, Projects, and Dissertations

Background: Gut health gained significant attention in recent years, with prebiotics and probiotics widely promoted for their potential health benefits. However, misinformation about this topic was common, particularly among young adults who were heavily influenced by social media and advertising on health-related topics. Research studies had indicated that knowledge and perceptions of prebiotics and probiotics are based on factors such as age, gender, and academic background. This study aimed to assess the knowledge and perceptions of university students on prebiotic and probiotic foods, identify commonly used resources for information, and analyze the impact of media and demographic variables on their …

Predicting Music Origin With Deep Learning, Fruzsina Ladanyi

Electronic Theses, Projects, and Dissertations

This project explores the usage of a late fusion deep learning architecture to predict the geographic origin of music. Mel-Frequency Cepstral Coefficients (MFCCs) and the language of the music sample are used as features. MFCCs were extracted from audio files to capture sound features. The language was identified using OpenAI’s Whisper model to provide additional context. A late fusion neural network architecture combining Long Short-Term Memory (LSTM) layers for sequential MFCC input and dense layers for non-sequential language features were employed to support both classification and regression tasks. The classification model achieved an accuracy of 33.03% across 56 countries or …

Addressing Jail Recidivism Among Inmates With Substance Use Disorders Through Treatment Interventions: A Scoping Review, Rosa C. Contreras

Electronic Theses, Projects, and Dissertations

This project studies effective treatments for formerly incarcerated individuals with substance use disorders (SUD’s) who become homeless. This study examines evidence-based, non-pharmaceutical interventions identified in current research, analyzing their effectiveness in addressing key social issues. It explores how these interventions contribute to improving outcomes for individuals and communities, particularly in areas such as mental health, addiction recovery, and rehabilitation. Additionally, the study assesses their significance within the field of social work, emphasizing their role in shaping policies, informing best practices, and fostering more holistic, client-centered approaches to care. The potential impact of these interventions is considered in relation to reducing …

Using The Dash Diet To Create Hypertensive-Friendly Dishes For People Of Chinese Heritage, Kady Li

Electronic Theses, Projects, and Dissertations

Cardiovascular disease is the leading cause of death worldwide, associated with high sodium intake being a primary contributor to elevated blood pressure. The US Dietary Guidelines for sodium intake is 2,300 mg per day; however, studies indicate that the average daily sodium consumption among Chinese adults is 5,013 mg. The Dietary Approaches to Stop Hypertension (DASH) diet is often recommended to those diagnosed with hypertension. This project aims to develop a cookbook featuring lower-sodium Chinese recipes following the DASH diet guidelines. Twenty-five traditional Chinese recipes were modified to align with DASH diet guidelines (25% reduction in sodium content). Nutrient analysis …

Lgbt+ Poc Well-Being And Resilience, Terra Reynoso

Electronic Theses, Projects, and Dissertations

Historically, both LGBT+ individuals and People of Color have each been subjected to stressors linked to oppression, with those belonging to both groups experiencing a potentially higher degree of distress. This study examined factors that contribute to resilience and well-being in LGBT+ People of Color to highlight potential means to mitigate this distress, guided by queer theory and intersectionality theory in order to provide a relevant framework to inform preliminary research, interview questions, and content analysis. Interviews were conducted with twelve participants with subsequent content analysis revealing the use of social support networks, access to community, productive coping strategies, and …

Projecting Echoes: Valeria Luiselli's Writing On Immigration, Jacob C. Cisneros

Electronic Theses, Projects, and Dissertations

The growing concerns of immigration has been a fraught topic in both U.S. society and the American political landscape. Certain political narratives are formed which fuel the debate for and against immigration. This coincides with how immigrants are treated and how legal processes change throughout each term of presidency within the United States. This has sparked outrage from both advocates and adversaries of immigrants coming into the United States. Papers, speeches, news articles, and more have been created from both sides of the argument concerning how to handle the immigration crisis along with the question of how immigrants and asylum …

Medical Surveillance In Custodial Jsas: Preventing Bloodborne Pathogen Exposure, Kiara Gadea

Electronic Theses, Projects, and Dissertations

Custodians play an important role in maintaining our surroundings safe and sanitary. However, in doing so, they are their exposure to health hazards that put them at risk, yet these exposures are often overlooked. One major risk they face is contact with bloodborne pathogens, which put custodial staff at risk for infections such as hepatitis B. While Job Safety Analyses (JSA’s) outline various protective measures, many fail to incorporate medical surveillance as part of their risk management program. Overlooking this important detail leaves custodians vulnerable to health risks that can be prevented.

Adding a medical surveillance section to custodial JSA’s, …

Fact-Checker: A Web Application For Leveraging Large Language Models For Fact-Checking Youtube Videos, Andrew R. Craig

Electronic Theses, Projects, and Dissertations

Fact-Checker is a web application that allows users to fact-check YouTube videos. It feeds YouTube’s closed captioning transcript to a large language model (LLM) to extract claims. It then uses multiple LLMs, such as Gemini, Llama, and Claude, to verify these claims. The modular design makes it easy to change to a different LLM or model if needed. The application is built using Python for access to Application Programming Interfaces (APIs) and Streamlit as the front-end framework. The utilization of Docker and Dockerfiles enables easy distribution and deployment. It enables the application to be deployed on almost any hardware platform …

De Novo And Inherited Variants In Ddx39b Cause A Novel Neurodevelopmental Syndrome, Kevin T A Booth, Sharayu V Jangam, Martin M C Chui, Kayla Treat, Lorenzo Graziani, Alessia Soldano, Yao Ruan, Jeffrey Wan-Hei Hui, Kerry White, Celanie K Christensen, Ty Lynnes, Shinya Yamamoto, Oguz Kanca, Mandy H Y Tsang, Sally A Lynch, Sureni V Mullegama, Julia Baptista, Daniela Iancu, Shelagh K Joss, Sandra Y Y Wong, Christopher C Y Mak, Anna K Y Kwong, Hugo J Bellen, Erin Conboy, Remo Sanges, Anskar Yu-Hung Leung, Michael F Wangler, Brian H Y Chung, Francesco Vetrini

Duncan NRI Faculty and Staff Publications

DDX39B is a conserved member of the DEAD-box family of ATP-dependent RNA helicases, critical in mRNA metabolism across eukaryotes. DDX39B is also a core component of the TRanscription-EXport (TREX) super protein complex, and recent studies have highlighted the important role of its subunits in neurodevelopmental disorders. Here, we describe six individuals from five families, four harbouring de novo missense variants in DDX39B and one with an inherited splicing variant, presenting with variable developmental delay, congenital hypotonia, epilepsy, short stature, skeletal abnormalities, dysmorphic features and microcephaly in three patients.

3D molecular modelling predicts these variants would alter protein structure. In vitro …

Folliculin Depletion Results In Liver Cell Damage And Cholangiocarcinoma Through Mit/Tfe Activation, Bruno Maria Custode, Francesco Annunziata, Felipe Dos Santos Matos, Valentina Schiano, Veronica Maffia, Milena Lillo, Rita Colonna, Rossella De Cegli, Andrea Ballabio, Nunzia Pastore

Duncan NRI Faculty and Staff Publications

Mutations in the tumor suppressor gene Folliculin (FLCN) are responsible for Birt-Hogg-Dube’ (BHD) syndrome, a rare inherited condition that predisposes affected individuals to skin tumors, pulmonary cysts, and kidney tumors. FLCN regulates key cellular pathways, including TFEB, TFE3, and mTORC1, which are critical for maintaining cell homeostasis. Loss of FLCN leads to both hyperactivation of mTORC1 and constitutive activation of TFEB and TFE3, contributing to tumorigenesis. While previous studies showed that Flcn liver-specific conditional knockout (FlcnLiKO) mice are protected from developing liver fibrosis and damage upon high-fat diet exposure, the potential role of FLCN loss in liver carcinogenesis …

Rapid Dissection And Dissociation Of The Mouse Olfactory Epithelium For Single-Nucleus Suspensions, Benjamin D W Belfort, Anthony M Insalaco, Claude C Chew, Johnathan D Jia, Julia Younis, Benjamin R Arenkiel

Duncan NRI Faculty and Staff Publications

The murine olfactory epithelium is the initial entry point of the olfactory system, housing various cell types that include olfactory sensory neurons, their regenerating progenitors, and support cells. Olfactory sensory neurons transduce chemical odorants into neural signals, yet the mechanisms underlying how these cells develop and turnover, create synapses with the olfactory bulb, and regulate their odorant receptors remain areas of intense study. Located on the dorsal aspect of the nasal cavity, the olfactory epithelium adheres to intricate bony structures known as turbinates. This anatomy poses unique challenges for its extraction and dissociation, especially in the context of preparing viable …

Borderplex Business Barometer, Volume 9, Number 8, Thomas M. Fullerton, Steven L. Fullerton

Border Region Modeling Project

No abstract provided.

Advancement Of Biocarbon Materials In Sustainable Thermal And Electrochemical Energy Storage With Future Outlooks, Md Shahriar Mohtasim, Barun K. Das

Research outputs 2022 to 2026

Biocarbon exhibits significant potential in thermal and electrochemical energy storage owing to its higher surface area, flexible porosity, and superior thermal stability, facilitating effective energy absorption, storage, and conversion. Additionally, its sustainable and cost-effective nature, derived from renewable biomass, aligns with the growing demand for eco-friendly solutions. There is not enough review work that offers comprehensive details on the unique properties of biocarbon (both animal and plant-derived), synthesis and characterization methods, the root level mechanism of biocarbon's interaction with phase change materials (PCMs) matrix, the generalization of thermal and electrochemical regulation with an emphasis on the benefits to the environment …