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A Difficult Act To Maintain, J.G. Allen Sep 2025

A Difficult Act To Maintain, J.G. Allen

Research Collection Yong Pung How School Of Law

In "Where is Singapore's AI regulation headed?" (Issues, Summer 2025), Manoj Harjani starts by recounting its delicate balancing act in governing artificial intelligence. The city-state is able to maintain credibility on the global stage while remaining pragmatically grounded in technical experimentation, maintaining policy realism without overcommitting to rigid legal frameworks. The choice to adopt a regulatory “light touch” is often framed as a way to maintain flexibility, avoid overregulation, and enable innovation. But this obscures the extent to which this posture is itself a political and economic settlement—one that reinforces Singapore’s position in the global digital economy by facilitating capital …

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(When) Can Trade Wars Be Good?, Henry S. Gao, Weihuan Zhou Sep 2025

(When) Can Trade Wars Be Good?, Henry S. Gao, Weihuan Zhou

Research Collection Yong Pung How School Of Law

‘Trade wars are good, and easy to win,’ tweeted Donald Trump in 2018. The US–China trade war that followed proved otherwise – especially when confronting a major economic power. Yet, can trade wars ever be good? While the academic consensus holds they harm all participants, we argue that under certain circumstances they can produce positive outcomes. Set against the backdrop of the Liberation Day tariffs announced on April 2, 2025, this paper examines the limits of the Ricardian free trade model underpinning the current multilateral trading system, identifies when trade wars may serve strategic goals, and explores alternative rules to …

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Accordance And Conflict Between Religious And Scientific Precautions Against Covid-19 In 27 Societies, T. Samore, D.M.T. Fessler, A.M. Sparks, C. Holbrook, L. Aarøe, C.G. Baeza, M.T. Barbato, P. Barclay, R. Berniūnas, J. Contreras-Garduño, B. Costa-Neves, M.P. Grazioso, P. Elmas, P. Fedor, Li, Norman P., R. Fernández-Morales, L. Garcia-Marques, P. Giraldo-Perez, P. Gul, F. Habacht Sep 2025

Accordance And Conflict Between Religious And Scientific Precautions Against Covid-19 In 27 Societies, T. Samore, D.M.T. Fessler, A.M. Sparks, C. Holbrook, L. Aarøe, C.G. Baeza, M.T. Barbato, P. Barclay, R. Berniūnas, J. Contreras-Garduño, B. Costa-Neves, M.P. Grazioso, P. Elmas, P. Fedor, Li, Norman P., R. Fernández-Morales, L. Garcia-Marques, P. Giraldo-Perez, P. Gul, F. Habacht

Research Collection School of Social Sciences

Meaning-making systems underlie perceptions of the efficacy of threat-mitigating behaviors. Religion and science both offer threat mitigation, yet these meaning-making systems are often considered incompatible. Do such epistemological conflicts swamp the desire to employ diverse precautions against threats? Or do individuals—particularly individuals who are highly reactive to threats—hedge their bets by using multiple threat-mitigating practices despite their potential epistemological incompatibility? Complicating this question, perceptions of conflict between religion and science likely vary across cultures; likewise, pragmatic features of precautions prescribed by some religions make them incompatible with some scientifically-based precautions. The COVID-19 pandemic elicited diverse precautions thus providing an opportunity …

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The Regulatory Challenges Raised By The Evolution From Open Banking To Banking-As-A-Service, Nydia Remolina Leon Sep 2025

The Regulatory Challenges Raised By The Evolution From Open Banking To Banking-As-A-Service, Nydia Remolina Leon

Research Collection Yong Pung How School Of Law

In May 2024, a company in California suddenly made headlines across the financial press. Synapse Financial Technologies, once hailed as a pioneer in the next wave of financial innovation, filed for bankruptcy. The company had promised to revolutionize banking by providing “Banking-as-a-Service” (BaaS): an invisible layer of technology that allowed apps to plug directly into the financial system.

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Strengthening The International Competitiveness Of Capital Markets: Global Insights And Local Strategies, Aurelio Gurrea-Martinez Sep 2025

Strengthening The International Competitiveness Of Capital Markets: Global Insights And Local Strategies, Aurelio Gurrea-Martinez

Research Collection Yong Pung How School Of Law

Global capital markets are undergoing a profound transformation. Over the past decade, there has been a marked decline in Initial Public Offerings (IPOs) in most advanced economies, including those with highly developed capital markets such as the United Kingdom and the United States. Interestingly, during the same period, countries like Indonesia, Malaysia, Thailand and particularly China, have witnessed a significant increase in the number of listed companies, contributing to making Asia home to approximately 55% of all listed companies worldwide. The decline in IPO activity has prompted many countries and regions around the world, including the United Kingdom, the United …

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A Commitment Rule For Insolvency Forum: A Response To Critics, Anthony J. Casey, Aurelio Gurrea-Martinez, Robert K. Rasmussen Sep 2025

A Commitment Rule For Insolvency Forum: A Response To Critics, Anthony J. Casey, Aurelio Gurrea-Martinez, Robert K. Rasmussen

Research Collection Yong Pung How School Of Law

On September 14, 2023, we sent a letter to the Secretariat of the United Nations Commission on International Trade Law (“UNCITRAL”) Working Group V (Insolvency) expressing our concern about the concept of “Center of Main Interest” (“COMI”) adopted in the Model Law on Cross-Border Insolvency (“Model Law”).1 We noted that the concept of COMI presents various weaknesses.

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A Multifaceted Nudge-Based Intervention To Reduce Smartphone Use: Findings From A Randomized Cross-Over Trial, K. T. A. Sandeeshwara Kasturiratna, Yi Jing Chua, Andree Hartanto Sep 2025

A Multifaceted Nudge-Based Intervention To Reduce Smartphone Use: Findings From A Randomized Cross-Over Trial, K. T. A. Sandeeshwara Kasturiratna, Yi Jing Chua, Andree Hartanto

Research Collection School of Social Sciences

The widespread use of smartphones has raised concerns about problematic usage behaviors, including excessive screentime and frequent phone checking, which can disrupt daily functioning. This study aimed to evaluate the effectiveness of a multifaceted nudge-based intervention in reducing smartphone use through subtle changes to smartphone settings. The intervention incorporated adjustments such as disabling face/touch ID, setting longer passwords, switching to grayscale mode, and removing social media apps from the home screen. A randomized within-subject cross-over trial with counterbalancing was conducted over a two-week period using a daily diary approach paired with objective smartphone usage data to track the impact of …

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Prevalence Of Depression, Anxiety, Burden, Burnout, And Stress In Informal Caregivers: An Umbrella Review Of Meta-Analyses, Xun Ci Soh, Andree Hartanto, Naoki Ling, Mayr Reyes, Lester Sim, Nadyanna M. Majeed Sep 2025

Prevalence Of Depression, Anxiety, Burden, Burnout, And Stress In Informal Caregivers: An Umbrella Review Of Meta-Analyses, Xun Ci Soh, Andree Hartanto, Naoki Ling, Mayr Reyes, Lester Sim, Nadyanna M. Majeed

Research Collection School of Social Sciences

Informal caregiving is a physically and emotionally taxing role that has a profound impact on caregivers’ emotional and mental well-being. Previous research has examined the mental health of caregivers and found elevated levels of depression, anxiety, burden, burnout, or stress. However, the global rates of the five mental health factors and/or outcomes (i.e., depression, anxiety, burden, burnout, and stress) among caregivers remain largely unclear. Therefore, this umbrella review examines the prevalence of these factors and/or outcomes, including various subgroup factors, such as gender, medical and/or psychological condition of the care recipient, region, and assessment tools. A systematic search was conducted …

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The Return Of Chinese Emigrants: Legal Barriers And Local Practices, Jiaqi M. Liu Sep 2025

The Return Of Chinese Emigrants: Legal Barriers And Local Practices, Jiaqi M. Liu

Research Collection School of Social Sciences

While China has observed an increasing influx of foreign nationals, a notable phenomenon involves Chinese emigrants opting for return migration to reestablish themselves in their country of origin. The process of emigrants returning to China, referred to as “return and resettlement” (huiguo dingju 回国定居) in official terminology, however, is not automatic. Emigrant returnees must fulfill a set of selective and documentary criteria, implying that only economically affluent and duly documented migrants are permitted to resettle in China. Through a comprehensive review of national policies and an analysis of local practices in a diaspora hometown, this chapter argues that the hukou …

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Reimagining Academic Assessment In The Age Of Ai, Matthew Hammerton Sep 2025

Reimagining Academic Assessment In The Age Of Ai, Matthew Hammerton

Research Collection School of Social Sciences

In ‘Reimagining Academic Assessment in the Age of AI’, Matthew Hammerton examines the challenges and opportunities posed by generative AI for higher education assessment. He critiques common responses like banning AI, reverting to in-class exams, or abandoning essays altogether, arguing that they fail to preserve the deeper pedagogical goals of higher order, independent thinking. Instead, Hammerton proposes a guiding principle of intellectual responsibility: students should be accountable for explaining and defending each major choice in their work—regardless of whether they use AI tools. To operationalise this, he advocates for reintegrating oral examinations (‘vivas’) alongside written essays. In this model, students …

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Lower Limb Muscle Strength Matters: Effect Of Relative Isometric Strength On Countermovement And Rebound Jump Performance In Elite Youth Female Soccer Players, Jack Fahey, Paul Comfort, Nicholas Joel Ripley Sep 2025

Lower Limb Muscle Strength Matters: Effect Of Relative Isometric Strength On Countermovement And Rebound Jump Performance In Elite Youth Female Soccer Players, Jack Fahey, Paul Comfort, Nicholas Joel Ripley

Research outputs 2022 to 2026

Background: Expression of maximal and rapid force in the hip, knee, and plantar flexors is important for athletic performance in female soccer. This study was designed to determine the effect of relative isometric strength in the isometric mid-thigh pull (IMTP) on countermovement jump (CMJ) and rebound jump (CMJ-R) performance in female youth soccer players. Methods: Ninety-six female soccer players (age: 14.1 ± 2.3 years, height: 160.5 ± 9.7 cm, mass: 55.0 ± 10.3 kg) completed three trials of the IMTP, CMJ, and CMJ-R using force plates. Players were categorized as stronger (top quartile, n = 19) and weaker players (bottom …

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Renewable-Based Isolated Power Systems: A Review Of Scalability, Reliability, And Uncertainty Modeling, Mehrdad Ghahramani, Daryoush Habibi, Seyyedmorteza Ghamari, Hamid Soleimani, Asma Aziz Sep 2025

Renewable-Based Isolated Power Systems: A Review Of Scalability, Reliability, And Uncertainty Modeling, Mehrdad Ghahramani, Daryoush Habibi, Seyyedmorteza Ghamari, Hamid Soleimani, Asma Aziz

Research outputs 2022 to 2026

Electric power systems are increasingly becoming more decentralized. Many communities depend on isolated power systems that operate independently of the main grid. Remote, islanded, and isolated systems face challenges due to the intermittency and unpredictability of renewable energy sources. This paper reviews the current status of renewable integration and control in stand-alone power systems. It examines techniques to enhance system reliability through energy storage, hybrid systems, and advanced predictive models. Additionally, the issues related to connecting stand-alone systems, focusing on reliability and renewable penetration, are discussed. The scalability of stand-alone power systems is analyzed based on classifications of small-, medium-, …

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Thermal Fatigue Failure Mechanisms And Enhancement Strategies Of Die Steel, Chuan De Li, Hong Yu Yang, Bai Xin Dong, De Li Chen, Shi Li Shu, Feng Qiu, Qi Chuan Jiang, Lai Chang Zhang Sep 2025

Thermal Fatigue Failure Mechanisms And Enhancement Strategies Of Die Steel, Chuan De Li, Hong Yu Yang, Bai Xin Dong, De Li Chen, Shi Li Shu, Feng Qiu, Qi Chuan Jiang, Lai Chang Zhang

Research outputs 2022 to 2026

Thermal fatigue failure is the core issue that restricts the development of die-casting technology, and it directly impacts the lifespan of the dies and the resulting economic benefits. This article reviews the fundamental mechanisms of thermal fatigue failure of die steels, classifies the potential failure mechanisms and discusses them in detail. This article examines the pivotal factors that affect the thermal fatigue resistance of die steels from four perspectives: alloying elements, processing techniques, microstructure, and inherent properties. On this basis, this article summarizes the advantages and disadvantages of various methods to enhance thermal fatigue resistance, such as alloying element optimization, …

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Electromagnetic Treatment Enhancing Performance Of Metal Materials: A Review, Lechun Xie, Hongxin Sun, Yan Wen, Lin Hua, Lai Chang Zhang Sep 2025

Electromagnetic Treatment Enhancing Performance Of Metal Materials: A Review, Lechun Xie, Hongxin Sun, Yan Wen, Lin Hua, Lai Chang Zhang

Research outputs 2022 to 2026

Due to the limitations of traditional metal processing methods, including high energy consumption, slow process dynamics and possible introduction of defects, electromagnetic treatment has been highlighted as a more environment-friendly and energy-efficient alternative, which can efficiently and selectively enhance material properties. This article summarizes the latest advances in electromagnetic treatment of metal materials to enhance material performance and outlooks the directions in electromagnetic treatment technology. It delves into electromagnetic field applications in manipulating the microstructure and properties. First, it explores the potential mechanisms of interaction between electromagnetic fields and metal materials, including thermal and athermal effects. Afterwards, it provides a …

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The Significance Of Blockchain Technology In Preserving Digital Evidence Integrity In Forensic Investigations, Marwa Popal, Ashfaq Ahmad, Muhammad Arshad Sep 2025

The Significance Of Blockchain Technology In Preserving Digital Evidence Integrity In Forensic Investigations, Marwa Popal, Ashfaq Ahmad, Muhammad Arshad

Research Outputs: 2025-Present

Digital forensics is the application of technology to the investigation and accounting of digital crime and the extraction and analysis of digital evidence from systems and networks. As the number of IoT [Internet of Things] devices has proliferated, the complexity inherent in forensic investigations has skyrocketed. While IoT forensics addresses the challenges of a lack of standardized security protocol and ensuring the integrity as well as security of evidence data, it brings to bear all the difficulties existing in classic forensics. Unfortunately, traditional digital forensic tools are generally inadequate in shielding that evidence from tampering or unauthorized access. Digital evidence …

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A Novel Robust Optimization Approach For Supply Chain Resilience: The Role Of Flexibility And Collaboration, Seyed Ashkan Hosseini Shekarabi, Reza Kiani Mavi, Neda Kiani Mavi, Flavio Romero Macau, Sobhan (Sean) Arisian Sep 2025

A Novel Robust Optimization Approach For Supply Chain Resilience: The Role Of Flexibility And Collaboration, Seyed Ashkan Hosseini Shekarabi, Reza Kiani Mavi, Neda Kiani Mavi, Flavio Romero Macau, Sobhan (Sean) Arisian

Research outputs 2022 to 2026

Supply chains are increasingly vulnerable to disruptive events that impair performance and stability. Despite research on supply chain resilience, a significant gap remains in risk management approaches on how to simultaneously minimize expected costs and control extreme cost variations. Existing methods neglect to narrow the gap between worst-case and best-case outcomes and to quantify the economic benefit of enhanced information in decision-making under uncertainty. This gap underscores the need for an integrated robust optimization framework that balances expected cost and risk while incorporating the assessment of novel digital technologies. In response, this study proposes a two-stage stochastic mixed-integer nonlinear programming …

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Deep Learning For Land Use Classification: A Systematic Review Of Hs-Lidar Imagery, Muhammad Zia Ur Rehman, Syed Mohammed Shamsul Islam, David Blake, Anwaar Ulhaq, Naeem Janjua Sep 2025

Deep Learning For Land Use Classification: A Systematic Review Of Hs-Lidar Imagery, Muhammad Zia Ur Rehman, Syed Mohammed Shamsul Islam, David Blake, Anwaar Ulhaq, Naeem Janjua

Research outputs 2022 to 2026

Remote sensing (RS) technologies have significantly advanced Earth observation capabilities, enhancing the characterization and identification of surface materials through both spaceborne and airborne systems. These advancements are crucial for improving environmental monitoring and urban planning. As RS datasets have become more accessible, their increased complexity has necessitated a shift from traditional machine learning techniques to more robust deep learning approaches, particularly convolutional neural networks (CNNs) and transformer-based models known for their superior feature extraction capabilities. This systematic review focuses on the application of these deep learning techniques in land use classification, emphasizing the fusion of hyperspectral (HS) and LiDAR data. …

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Mitigating The Supply Chain Uncertainties And Risks In The Construction Projects: Case Studies Of Australian Construction Projects, Ming Juan Ding, Ferry Jie Sep 2025

Mitigating The Supply Chain Uncertainties And Risks In The Construction Projects: Case Studies Of Australian Construction Projects, Ming Juan Ding, Ferry Jie

Research outputs 2022 to 2026

Mitigating the supply chain uncertainties and risks has become increasingly crucial for project managers to enhance construction project performance. This paper investigates how companies develop risk mitigation frameworks to address the challenges such as disruptive risks, project delays, cost overrun within construction supply chains. The risk mitigation framework developed is more significant compared with other frameworks as it considers further the unique characteristics of a temporary configuration of construction supply chains and the network is particularly vulnerable to some adverse events. Through multiple case studies, this research examines how various stakeholders in construction supply chains manage the risks during and …

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Optimizing Initial Screening For Colorectal Cancer Detection With Adherence Behavior, Sarah Yini Gao, Yan He, Ruijie Zhang, Zhichao Zheng, Shao Wei Lam Lam, Emile Tan Sep 2025

Optimizing Initial Screening For Colorectal Cancer Detection With Adherence Behavior, Sarah Yini Gao, Yan He, Ruijie Zhang, Zhichao Zheng, Shao Wei Lam Lam, Emile Tan

Research Collection Lee Kong Chian School Of Business

Background: Two-stage screening programs are widely adopted for early colorectal cancer (CRC) detection, where individuals receiving positive outcomes in the first-stage (initial) test are recommended to undergo a second-stage test (colonoscopy) for further diagnosis. Methods: We study the initial test design—the selection of cutoffs for reporting test outcomes—to balance the trade-off between screening effectiveness (i.e., CRC and polyp detection) and efficiency (i.e., colonoscopy costs), incorporating the fact that not all individuals follow up with a colonoscopy after receiving positive outcomes. We integrate the Bayesian persuasion framework with information avoidance to model this problem and apply it to Singapore's CRC screening …

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Why Stressed Candidates Make Better Cross-Cultural Hires, Shilpa Madan Sep 2025

Why Stressed Candidates Make Better Cross-Cultural Hires, Shilpa Madan

Research Collection Lee Kong Chian School Of Business

When interviewing job candidates, you may look for evidence that they stay calm under pressure and interpret signs of stress as red flags. However, our recent research shows that for cross-cultural positions, those red flags might actually indicate your best potential hires. Candidates who exhibit signs of stress may be better suited to navigate the complexities of cross-cultural roles, suggesting a need to reassess traditional interview evaluations.

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Esg News, Future Cash Flows, And Firm Value, Francois Derrien, Philipp Krüger, Augustin Landier, Tianhao Yao Sep 2025

Esg News, Future Cash Flows, And Firm Value, Francois Derrien, Philipp Krüger, Augustin Landier, Tianhao Yao

Research Collection Lee Kong Chian School Of Business

We investigate the expected consequences of negative environmental, social, and governance (ESG) news on firms' future profits. After learning about negative ESG news, analysts significantly downgrade their forecasts at short and longer horizons. Negative ESG news affects forecasts more strongly at longer horizons than other types of negative corporate news. The negative revisions of earnings forecasts following negative ESG news largely reflect expectations of lower future sales, rather than higher future costs. Quantitatively, forecast revisions can explain most of the negative impacts of ESG news on firm value. Analysts are correct to revise forecasts downward following negative ESG news.

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Learning Camp, Language Of Instruction, And Education Outcomes: Evidence From A Field Experiment In Malawi, Hyuncheol Bryant. Kim, Kim Sep 2025

Learning Camp, Language Of Instruction, And Education Outcomes: Evidence From A Field Experiment In Malawi, Hyuncheol Bryant. Kim, Kim

Research Collection School Of Economics

We conducted a randomized experiment to study the impacts of a summer learning camp and the language of instruction on education outcomes. The program, covering social studies and mathematics, provided additional high-quality learning time for 4th and 5th graders in Malawi. The program significantly increased test scores in social studies and mathematics (0.24–0.36 standard deviations). We find suggestive evidence that the impact on test scores in social studies was greater for students instructed in Chichewa, the local language, than for those instructed in English. However, we find no such evidence of differential impacts on test scores in mathematics by the …

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A General Test For Functional Inequalities, Jia Li, Zhipeng Liao, Wenyu Zhou Sep 2025

A General Test For Functional Inequalities, Jia Li, Zhipeng Liao, Wenyu Zhou

Research Collection School Of Economics

This paper develops a nonparametric test for general functional inequalities that include conditional moment inequalities as a special case. It is shown that the test controls size uniformly over a large class of distributions for observed data, importantly allowing for general forms of time series dependence. New results on uniform growing dimensional Gaussian coupling for general mixingale processes are developed for this purpose, which readily accommodate most applications in economics and finance. The proposed method is applied in a portfolio evaluation context to test for “all-weather” portfolios with uniformly superior conditional Sharpe ratio functions.

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Merit Transference And The Paradox Of Merit Inflation, Matthew Hammerton Sep 2025

Merit Transference And The Paradox Of Merit Inflation, Matthew Hammerton

Research Collection School of Social Sciences

Many religious traditions and ethical systems hold that individuals accrue merit through their good intentions, acts, and character, and demerit through their bad intentions, acts, and character. This merit and demerit, accumulated by individuals throughout their lives, gives each person a kind of ethical “score” that can determine what they deserve, and influence whether good or bad things happen to them (e.g., divine punishments and rewards, a favourable or unfavourable rebirth, etc.). In some traditions (most notably Buddhism, but also to a limited extent in Hinduism, Islam, and Christianity), “merit transference” is a feature of these merit-based ethical systems. This …

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Patterns Of Ecological Quality In Portuguese Transitional Waters Over The Last Five Decades: A Framework Based On Benthic Foraminifera For The Sado Estuary, J. Moreno, F. Moreno, F. Fatela, E. Leorri, M. Leira, P. Masqué, M. C. Freitas Sep 2025

Patterns Of Ecological Quality In Portuguese Transitional Waters Over The Last Five Decades: A Framework Based On Benthic Foraminifera For The Sado Estuary, J. Moreno, F. Moreno, F. Fatela, E. Leorri, M. Leira, P. Masqué, M. C. Freitas

Research outputs 2022 to 2026

This study aimed to examine the validity of benthic foraminifera-based indices – Foraminiferal Stress Index (FSI), diversity index Exp(H'bc), and Ecological Quality Ratio (EQR) – for evaluating estuarine environmental conditions and supporting palaeoecological reconstructions, focusing on the Sado estuary (southwest Portugal). Located near heavily industrialized urban areas and designated as a Nature Reserve, this estuary faces human pressures and high natural values, leading to management conflicts. Foraminiferal assemblages were analysed in surface sediment samples, with known concentrations of several metal(loid)s, and in dated core samples. Correlations were found between metal(loid)s, organic matter, grain size, and salinity (as a proxy for …

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The Outcomes Of A Structured Bowel Management Programme On Childhood Functional Constipation: A Retrospective Pre – Post Intervention Study, Gunilla Flankegård, Peter Wide, Evalotte Mörelius Sep 2025

The Outcomes Of A Structured Bowel Management Programme On Childhood Functional Constipation: A Retrospective Pre – Post Intervention Study, Gunilla Flankegård, Peter Wide, Evalotte Mörelius

Research outputs 2022 to 2026

Aim: The purpose of this study was to describe and evaluate the effectiveness of a six-month structured bowel management programme (SBMP) for children with therapy-resistant functional constipation (FC). Method: A retrospective review of medical records with a pre-post design was conducted at an outpatient paediatric clinic in Sweden. Bowel frequency, stool form, faecal incontinence, and abdominal pain were compared before and after the intervention. Predictive factors for successful discharge and duration of care through long-term follow-up were calculated. Results: Of the 142 children enrolled in the SBMP, 132 completed the programme. Despite previous FC therapy resistance, the SBMP achieved a …

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A Large-Scale Multi-Centre Study Characterising Atrophy Heterogeneity In Alzheimer's Disease, Vikram Venkatraghavan, Damiano Archetti, Pierrick Bourgeat, Chenyang Jiang, Mara Ten Kate, Anna C. Van Loenhoud, Rik Ossenkoppele, Charlotte E. Teunissen, Elsmarieke Van De Giessen, Yolande A.L. Pijnenburg, Giovanni B. Frisoni, Béla Weiss, Zoltán Vidnyánszky, Tibor Auer, Stanley Durrleman, Alberto Redolfi, Simon M. Laws, Paul Maruff, Neil P. Oxtoby, Andre Altmann, Daniel C. Alexander, Wiesje M. Van Der Flier, Frederik Barkhof, Betty M. Tijms Sep 2025

A Large-Scale Multi-Centre Study Characterising Atrophy Heterogeneity In Alzheimer's Disease, Vikram Venkatraghavan, Damiano Archetti, Pierrick Bourgeat, Chenyang Jiang, Mara Ten Kate, Anna C. Van Loenhoud, Rik Ossenkoppele, Charlotte E. Teunissen, Elsmarieke Van De Giessen, Yolande A.L. Pijnenburg, Giovanni B. Frisoni, Béla Weiss, Zoltán Vidnyánszky, Tibor Auer, Stanley Durrleman, Alberto Redolfi, Simon M. Laws, Paul Maruff, Neil P. Oxtoby, Andre Altmann, Daniel C. Alexander, Wiesje M. Van Der Flier, Frederik Barkhof, Betty M. Tijms

Research outputs 2022 to 2026

Previous studies identified atrophy-based Alzheimer's disease(AD) subtypes linked to distinct clinical symptoms, but their consistency across subtyping approaches remains unclear. This large-scale study evaluates subtype concordance using two data-driven approaches. In this work, we analyzed data from n=10,011 patients across 10 AD cohorts spanning Europe, the US, and Australia, extracting regional volumes using Freesurfer. To characterize atrophy heterogeneity in the AD continuum, we developed a two-step approach, Snowphlake (Staging NeurOdegeneration With PHenotype informed progression timeLine of biomarKErs), to identify subtypes and atrophy-event sequences within each subtype. Results were compared with SuStaIn (Subtype and Stage Inference), which jointly estimates subtypes and …

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Automated Instance Segmentation And Registration Of Spinal Vertebrae From Ct-Scans With An Improved 3d U-Net Neural Network And Corner Point Registration, James Hill, Muhammad Rizwan Khokher, Chuong Nguyen, Matt Adcock, Ron Li, Stuart Anderson, Thomas Morrell, Tim Diprose, Olivier Salvado, Dadong Wang, Guan K. Tay Sep 2025

Automated Instance Segmentation And Registration Of Spinal Vertebrae From Ct-Scans With An Improved 3d U-Net Neural Network And Corner Point Registration, James Hill, Muhammad Rizwan Khokher, Chuong Nguyen, Matt Adcock, Ron Li, Stuart Anderson, Thomas Morrell, Tim Diprose, Olivier Salvado, Dadong Wang, Guan K. Tay

Research outputs 2022 to 2026

This paper presents a rapid and robust approach for 3D volumetric segmentation, labelling, and registration of human spinal vertebrae from CT scans using an optimised and improved 3D U-Net neural network architecture. The network is designed by incorporating residual and dense interconnections, followed by an extensive evaluation of different network setups by optimising the network components like activation functions, optimisers, and pooling operations. In addition, the network architecture is optimised for varying numbers of convolution layers per block and U-Net levels with fixed and cascading numbers of filters. For 3D virtual reality visualisation, the segmentation output of the improved 3D …

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Do Companies’ Green Credentials Enhance Trade Credit Provisions? Global Evidence, Rashid Zaman, Nader Atawnah, Deepa Banigidadmath, Muhammad Nadeem, Jia Liu Sep 2025

Do Companies’ Green Credentials Enhance Trade Credit Provisions? Global Evidence, Rashid Zaman, Nader Atawnah, Deepa Banigidadmath, Muhammad Nadeem, Jia Liu

Research outputs 2022 to 2026

We investigate the impact of corporate renewable energy (RE) adoption on suppliers’ trade credit provisions. Using a global sample of 30 countries, we establish that firms engaging in higher RE consumption secure increased trade credit. Our results remain robust to a variety of sensitivity tests and after accounting for potential endogeneity concerns using the Paris Agreement and companies switching to green energy as exogenous shocks. Our channel analysis reveals that RE take-up mitigates companies’ environmental risk (proxied by environmental violation fines, media coverage of environmental controversies, GHG emissions, and environmental policy stringency). Additional tests reveal that the relationship between RE …

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Temperature-Dependent Properties Of Cu-Doped Znte Thin Films Deposited On Slg Substrates Via Rf Magnetron Sputtering And E-Beam Techniques, Sherif Salah, Camellia Doroody, Fazliyana ‘Izzati Za'abar, Zheng Jie Feng, Prajindra Sankar Krishnan, Ahmad Wafi Mahmood Zuhdi, Muhammad Najib Harif, Nur Irwany Ahmad, Yap Boon Kar, Mohammad Nur-E-Alam Sep 2025

Temperature-Dependent Properties Of Cu-Doped Znte Thin Films Deposited On Slg Substrates Via Rf Magnetron Sputtering And E-Beam Techniques, Sherif Salah, Camellia Doroody, Fazliyana ‘Izzati Za'abar, Zheng Jie Feng, Prajindra Sankar Krishnan, Ahmad Wafi Mahmood Zuhdi, Muhammad Najib Harif, Nur Irwany Ahmad, Yap Boon Kar, Mohammad Nur-E-Alam

Research outputs 2022 to 2026

Copper doping in zinc telluride (ZnTe) thin films has been extensively studied for optoelectronic applications; however, challenges remain in optimizing temperature-dependent diffusion while minimizing defect-related emissions. Although numerous studies have explored Cu-doped ZnTe, comprehensive investigations using electron-beam (E-beam) evaporation remain limited, especially concerning its influence on diffusion dynamics, defect formation, and electrical properties. This study systematically examined Cu-doped ZnTe films fabricated via E-beam evaporation with a fixed 50 nm Cu layer deposited at three substrate temperatures (RT, 150 °C, and 300 °C), followed by rapid thermal annealing (RTA) at 100 °C and 200 °C for 1 h under a nitrogen …

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