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Blockchain-Powered Dynamic Segmentation In Personal Health Record, Mishall Al-Zubaidie, Wid Alaa Jebbar Sep 2025

Blockchain-Powered Dynamic Segmentation In Personal Health Record, Mishall Al-Zubaidie, Wid Alaa Jebbar

Mesopotamian Journal of CyberSecurity

Sensitive patient data must be handled securely in modern oncology care to protect patient privacy, regulatory compliance, and clinical decision-making integrity. Conventional centralized healthcare systems pose serious threats to patient confidentiality and treatment continuity because of their susceptibility to data breaches, illegal access, and single points of failure. This study suggests a blockchain-based decentralized cancer healthcare security solution. The proposed system is based on the idea of layers; each layer has a distinct function that gives it a feature that sets it apart from the others. A hierarchical clustering algorithm (HCA) is used in the first layer to determine the …


Priflex: A Secure Federated Learning Framework For Evaluating Privacy Leakage And Defense In Cross-Modal Medical Data, Mohammad Othman Nassar, Feras Fares Al-Mashagba Sep 2025

Priflex: A Secure Federated Learning Framework For Evaluating Privacy Leakage And Defense In Cross-Modal Medical Data, Mohammad Othman Nassar, Feras Fares Al-Mashagba

Mesopotamian Journal of CyberSecurity

Federated learning (FL) enables decentralized, privacy-preserving machine learning by training models across distributed data without sharing raw patient information. However, most FL frameworks focus on unimodal data and overlook critical challenges in multimodal healthcare settings, such as privacy risks, fairness disparities, and reduced model interpretability. We present PRIFLEX (Privacy-Resilient Integration Framework for Learning Exchange), a novel FL framework designed for secure integration of structured and unstructured medical data. PRIFLEX combines 12-lead electrocardiograms (ECG) from the PhysioNet PTB-XL dataset and clinical notes from the Medical Information Mart for Intensive Care IV (MIMIC-IV), supporting early, late, and hybrid data fusion strategies. To …


Blockchain-Based Accountability: A Systematic Literature Review, Nabeel Z. Tawfeeq, Dujan B. Taha Sep 2025

Blockchain-Based Accountability: A Systematic Literature Review, Nabeel Z. Tawfeeq, Dujan B. Taha

Mesopotamian Journal of CyberSecurity

The Blockchain algorithm has advanced the accountability and transparency of modern digital infrastructures. Enforcing responsible behavior and data integrity across distributed environments involves several key components, such as smart contracts, access control models, cryptographic techniques, and a decentralized identity framework. Because the blockchain ledger is immutable and transparent, once a transaction is recorded, it cannot be altered without detection, making fraudulent actions easily traceable and thereby ensuring accountability. However, the need for hybrid approaches that combine on-chain and off-chain solutions for an efficient reliability system introduces challenges, including privacy preservation, scalability, and regulatory compliance. This paper analyzes the effective features …


Global Research Trends And Collaboration In Mitre Att&Ck Framework: A Bibliometric And Network Analysis In Cybersecurity, Asad Maqsood, Syifak Izhar Hisham, Ahmad Firdaus Sep 2025

Global Research Trends And Collaboration In Mitre Att&Ck Framework: A Bibliometric And Network Analysis In Cybersecurity, Asad Maqsood, Syifak Izhar Hisham, Ahmad Firdaus

Mesopotamian Journal of CyberSecurity

The MITRE ATT&CK framework has become a foundational tool for organizing adversarial behaviors and techniques in cybersecurity. While its adoption in practice and academia has grown significantly, no prior bibliometric review has comprehensively mapped the global research landscape surrounding this framework. This study addresses that gap by conducting a systematic bibliometric and network analysis of publications related to ATT&CK indexed in Scopus from 2017 to 2025. Using VOSviewer and quantitative bibliometric methods, we analyzed 391 publications to identify trends in research output, influential works, key contributors, thematic areas, and patterns of collaboration. Results show exponential growth in studies related to …


A Proposed Algorithm For Avoiding Jammer In Structure-Free Wireless Sensor Networks, Zainab Shaker Matar Al-Husseini, Hussain K. Chaiel, Amel Meddeb, Ahmed Fakhfakh, Ahmed Fakhfakh Sep 2025

A Proposed Algorithm For Avoiding Jammer In Structure-Free Wireless Sensor Networks, Zainab Shaker Matar Al-Husseini, Hussain K. Chaiel, Amel Meddeb, Ahmed Fakhfakh, Ahmed Fakhfakh

Mesopotamian Journal of CyberSecurity

Wireless Sensor Networks (WSNs) have emerged as a transformative technology with applications in critical and often inaccessible environments, including military and security domains. These networks comprise cooperative sensor nodes that gather and relay data to a base station. However, their inherent resource constraints—particularly the non-rechargeable nature of energy—pose a major challenge to network longevity and reliability. Conventional fixed-path transmission protocols exacerbate this issue, as energy-depleted or jammed nodes can disrupt communication, leading to partial or complete data loss. The primary objective of this study is to design and evaluate a structure-free transmission protocol that dynamically adapts data routing in order …


Improvement Of The Face Recognition Systems Security Against Morph Attacks Using The Developed Siamese Neural Network, Sura Abed Sarab Hussien, Thair Abed Sarab Hussien, Nada Hussein M. Ali Sep 2025

Improvement Of The Face Recognition Systems Security Against Morph Attacks Using The Developed Siamese Neural Network, Sura Abed Sarab Hussien, Thair Abed Sarab Hussien, Nada Hussein M. Ali

Mesopotamian Journal of CyberSecurity

Face Recognition Systems (FRS) are increasingly targeted by morphing attacks, where facial features of multiple individuals are blended into a synthetic image to deceive biometric verification. This paper proposes an enhanced Siamese Neural Network (SNN)-based system for robust morph detection. The methodology involves four stages. First, a dataset of real and morphed images is generated using StyleGAN, producing high-quality facial images. Second, facial regions are extracted using Faster Region-based Convolutional Neural Networks (R-CNN) to isolate relevant features and eliminate background noise. Third, a Local Binary Pattern-Convolutional Neural Network (LBP-CNN) is used to build a baseline FRS and assess its susceptibility …


Mindfulness-Based Interventions For Adults With Coronary Artery Disease: An Integrative Review Of Impact On Risk Factors And Outcomes, Alexa Archer, Kristiina Hyrkas Sep 2025

Mindfulness-Based Interventions For Adults With Coronary Artery Disease: An Integrative Review Of Impact On Risk Factors And Outcomes, Alexa Archer, Kristiina Hyrkas

MaineHealth Maine Medical Center

Aim: To synthesize recent evidence on the effects of MBIs on psychological and cardiovascular health.


Ev Battery Next Lives, Asma Aziz, Bassam Al-Hanahi, Daryoush Habibi, Iftekhar Ahmad Sep 2025

Ev Battery Next Lives, Asma Aziz, Bassam Al-Hanahi, Daryoush Habibi, Iftekhar Ahmad

Other Reports

As the demand for lithium-ion (Li-ion) batteries grows, ensuring the availability of raw materials and addressing the environmental and social impacts of battery production and disposal have become vital concerns. Business models that give batteries a second life – through reuse, repurposing and recycling – can substantially reduce material needs and environmental effects. Over time, these practices may also unlock new domestic value streams, create job opportunities and reduce battery costs. This project is a comprehensive analysis of the end-of-life (EOL) electric vehicle (EV) battery landscape, focusing on circular economy principles and market valuation. It also examines the supply chain …


Cellulose Nanofiber/Chitosan/Polyrotaxane Foam Alloy For Sustainable Form-Stable Phase Change Materials, Xiao-Mei Yang, Luis Soliverdi Mesa, Adolfo Nadal Serrano, Guang-Zhong Yin Sep 2025

Cellulose Nanofiber/Chitosan/Polyrotaxane Foam Alloy For Sustainable Form-Stable Phase Change Materials, Xiao-Mei Yang, Luis Soliverdi Mesa, Adolfo Nadal Serrano, Guang-Zhong Yin

Artículos científicos

his study introduces a novel cellulose nanofiber (CNF)/Chitosan (CH)/polyrotaxane (PLR) foam alloy as a formstable PCM support material. The CNF/CH/PLR aerogel demonstrates a well-balanced porous structure with effective encapsulation of polyethylene glycol (PEG). Combining PLR with CNF/CH, the PEG leakage resistance was significantly improved. The resulting CNF/CH/20 %PLR-PEG composite exhibits exceptional enthalpy values of 181.1 J/g, along with superior mass retention rates under melting. These findings highlight the po tential of this bio-based composite for advanced thermal energy storage systems, offering a sustainable and efficient solution for energy-efficient applications


Generative Ai (Genai) For Co-Creating User Personas, Douglas Strahler Sep 2025

Generative Ai (Genai) For Co-Creating User Personas, Douglas Strahler

Proceedings of the New York State Communication Association

Integrating Generative AI into communication courses can really enhance the development of user personas, making the process smoother and encouraging critical insights into audience analysis. This G.I.F.T.S. presentation shows how tools like ChatGPT can support students in developing user personas while encouraging creativity and efficiency for the students. Students will be creating two personas, one human-created and one that is AI-generated, followed by conducting a comparative analysis of similarities, differences, and any potential biases. The activity underlines basic competencies in the development of user personas and ethical considerations that prepare students for the responsible use of AI with a full …


From Chatbots To Thought Bots: Teaching And Learning In The Age Of Ai, Stephen J. Mcconnell Sep 2025

From Chatbots To Thought Bots: Teaching And Learning In The Age Of Ai, Stephen J. Mcconnell

Proceedings of the New York State Communication Association

Dr. Stephen McConnell’s keynote address took place on Friday, October 18, 2025, at the 82nd Annual NYSCA Conference. In this personal but scholarly discussion, Dr. McConnell explores how various AI technologies do more than “assist” us – they also socialize us. He describes and explains several case studies that were part of his course at New York University entitled “Communications and AI,” and provides us with ten principles for teachers and students to become active participants with the tools of AI.

Dr. McConnell is a media scholar whose research focuses on the intersection of AI, digital communication platforms and …


Does Writing Have A Future?, David J. Gunkel Sep 2025

Does Writing Have A Future?, David J. Gunkel

Proceedings of the New York State Communication Association

Professor David J. Gunkel is the Chair of the Department of Communication at Northern Illinois University – but that is his latest achievement in an extensive list of accomplishments. He is an award-winning educator, researcher, and the author of more than ninety scholarly articles and thirteen books. And it is his latest book, AI for Communication, and his latest thinking about what we have called artificial intelligence and writing that brought him to our 82nd annual conference.

In his keynote address on Saturday, October 9th, 2024, Dr. Gunkel argues that AI does not signal the “end …


Harry Potter And The Queering Agenda*, Krisha K. Vania Sep 2025

Harry Potter And The Queering Agenda*, Krisha K. Vania

Proceedings of the New York State Communication Association

The Marauders Era, a newfound sub-fandom of Harry Potter, focuses on a group of characters set years before the original series. This community has allowed for alternative ‘safe’ spaces for fans to ‘queer’ the source material and find personal and social leverage. A survey was conducted to research how queer-identifying fans build and maintain virtual communities using the Wizarding World and Harry Potter mythology. The data and subsequent analysis reinforced the creation and maintenance of a participatory community through the use of multiple entry points, fans acting as textual poachers, and a community offering its users a form of leverage. …


The Evolution Of Women Behind The Wheel, Gabrielle Iorio Sep 2025

The Evolution Of Women Behind The Wheel, Gabrielle Iorio

Proceedings of the New York State Communication Association

This paper places the current state of women in motorsports in conversation with scholarship focused on media and cultural identity by providing historical context for women in motorsports while analyzing media representations of Danica Patrick and current racers Hailie Deegan, Toni Breidinger, and Tatiana Calderon. While great progress has been made in acceptance of women as professional race car drivers and in media representations of them, stereotypes still face these drivers when it comes to obtaining sponsorships and the types of sponsorships they receive.


Algorithmic Governance And The Boardroom: Empirical And Strategic Perspectives On Ai Integration In Corporate And Educational Oversight, James Hutson, Guarango Banerjee Sep 2025

Algorithmic Governance And The Boardroom: Empirical And Strategic Perspectives On Ai Integration In Corporate And Educational Oversight, James Hutson, Guarango Banerjee

Faculty Scholarship

The accelerating digitization of executive decision-making has prompted critical re-examination of the function and value of traditional boards of directors within corporate and educational institutions. Empirical research consistently reveals that human boards, while ostensibly tasked with strategic insight and fiduciary oversight, are frequently constrained by structural inefficiencies—such as director overcommitment, inflated compensation, and persistent conflicts of interest—that undermine organizational performance. Against this backdrop, the integration of Artificial Intelligence agents, either as analytic adjuncts or autonomous decision-makers, emerges as a plausible avenue for enhancing board effectiveness. This article synthesizes global case studies, peer-reviewed findings, and real-time technological developments to critically evaluate …


Nursing Students In The Simulation Laboratory, Circa 1972, Uab Archives Sep 2025

Nursing Students In The Simulation Laboratory, Circa 1972, Uab Archives

Images of the Month from UAB Archives

Image ID: MC51, #0126b

Nursing students in the simulation laboratory, circa 1972


Risk, Uncertainty, World Business Cycles, And The U.S. Stock-Oil Relationship, André Varella Mollick Sep 2025

Risk, Uncertainty, World Business Cycles, And The U.S. Stock-Oil Relationship, André Varella Mollick

School of Economics and Finance Faculty Publications

We examine in this paper the transmission of geopolitical risks (GPR), VIX, economic policy uncertainty (EPU), and “macro uncertainty” shocks to real WTI oil and U.S. stock returns (S&P 500). Structural vector autoregressions (SVAR) are applied to monthly data from 1990:1 to 2023:6 with identification based on long-run restrictions of impulse responses from risk/uncertainty measures to world industrial production. The main results are: First, oil prices respond positively to shocks in GPR and macro uncertainty in the short-run, but not to shocks in VIX and EPU. Second, stock returns respond negatively and for longer to both GPR and VIX shocks. …


Does Stem Design Affect Primary Stability Of Splined Tapered Fluted Stems? A Biomechanical Cadaver Study, Shuyang Han, Daniel C Mascarenhas, Camryn A Pletka, Jonathan E Gold, Sabir K Ismaily, Matthew Cao, Matthew W Brewer, Robert Frangie, Philip C Noble, David Rodriguez-Quintana Sep 2025

Does Stem Design Affect Primary Stability Of Splined Tapered Fluted Stems? A Biomechanical Cadaver Study, Shuyang Han, Daniel C Mascarenhas, Camryn A Pletka, Jonathan E Gold, Sabir K Ismaily, Matthew Cao, Matthew W Brewer, Robert Frangie, Philip C Noble, David Rodriguez-Quintana

Faculty, Staff and Student Publications

Background: Tapered fluted stems are an excellent solution for revision hip arthroplasty following periprosthetic fractures. However, existing implant designs differ in terms of the number of splines, taper angle, and cross-sectional design, and there is a lack of knowledge on the biomechanical effect of these design variations. Therefore, the objective of this study was to compare the primary stability of two representative stem designs and the extent and distribution of stem-bone contact in a periprosthetic fracture model. It was hypothesized that a greater number of splines would lead to greater stability.

Methods: There were six pairs of cadaver femora included …


Beyond Frequency Of Use: Exploring Additional Metrics For Quantifying Cocaine Use And Their Relation To Life Functioning And Treatment Outcome, Samantha Ellis, Rachel Sun, Angela Heads, Jin Ho Yoon, Heather Webber, Joy Schmitz, Margaret Wardle Sep 2025

Beyond Frequency Of Use: Exploring Additional Metrics For Quantifying Cocaine Use And Their Relation To Life Functioning And Treatment Outcome, Samantha Ellis, Rachel Sun, Angela Heads, Jin Ho Yoon, Heather Webber, Joy Schmitz, Margaret Wardle

Faculty, Staff and Student Publications

Background: Frequency of use - the number of days of use - is the most common metric for quantifying cocaine use and the most common target of treatment. However, frequency may not capture all important aspects of cocaine use. This study examined how other aspects of cocaine use (typical amount spent, variability etc.) relate to life functioning and cocaine use disorder (CUD) treatment outcomes.

Method: This is a secondary analysis of 3 clinical trials for CUD, N = 207 for the life functioning analysis and N = 173 for the outcomes analysis. Eight metrics of use were calculated from baseline …


Cysteine Oxidation Of A Redox Hub Within Complex I Can Facilitate Electron Transport Chain Supercomplex Formation, Runtai Chen, Seyed Amirhossein Tabatabaei Dakhili, Rokas Gerulskis, Yuan Yuan Zhao, Steven Lockhart, Lusine Tonoyan, Arno G. Siraki, Guocheng Huang, Adam Kinnaird, Darren H. Freed, Shelley D. Minteer, Evangelos D. Michelakis, John R. Ussher Sep 2025

Cysteine Oxidation Of A Redox Hub Within Complex I Can Facilitate Electron Transport Chain Supercomplex Formation, Runtai Chen, Seyed Amirhossein Tabatabaei Dakhili, Rokas Gerulskis, Yuan Yuan Zhao, Steven Lockhart, Lusine Tonoyan, Arno G. Siraki, Guocheng Huang, Adam Kinnaird, Darren H. Freed, Shelley D. Minteer, Evangelos D. Michelakis, John R. Ussher

Chemistry Faculty Research & Creative Works

The mitochondrial electron transport chain (ETC) is a four complex unit that could be considered the most essential infrastructure within the mitochondria, as it primarily functions to generate the mitochondrial membrane potential (ΔΨm), which can then be utilized for ATP synthesis or heat production. Another important aspect of ETC function is the generation of mitochondrial reactive oxygen species (mtROS), which are essential physiologic signaling mediators that can be toxic to the cell if their levels become too high. Currently, it remains unresolved how a highly utilized and functioning ETC can sense excessive mtROS generation and adapt, to enhance ΔΨm. Here, …


Development Of A Balanced Mix Design Approach For Stone Matrix Asphalt Mixtures, Bo Lin, Yizhuang David Wang, Jenny Liu Sep 2025

Development Of A Balanced Mix Design Approach For Stone Matrix Asphalt Mixtures, Bo Lin, Yizhuang David Wang, Jenny Liu

Civil, Architectural and Environmental Engineering Faculty Research & Creative Works

Stone Matrix Asphalt (SMA) has been widely used as a durable, high-quality mixture for primary roads. With the growing interest in incorporating innovative materials into SMA designs, developing effective and reliable mix design methodologies has become essential to ensure durability, sustainability, and cost-effectiveness. While performance tests have gained national acceptance for asphalt mix design and balanced mix design (BMD) methods have been adopted in many states for hot mix asphalt (HMA), SMA has not been fully considered with the BMD implementation. This study aimed to develop a BMD approach for SMA, incorporating both SMA-specific volumetric parameters and performance requirements. To …


Corneal Pseudomicrocysts Following Claudin-6 Antibody-Drug Conjugate Infusion, Laura Matuszewska, Caitlynn Cooper, Victoria Sattarova, Wassef Chanbour, Evan Meyer, Vania Rashidi Sep 2025

Corneal Pseudomicrocysts Following Claudin-6 Antibody-Drug Conjugate Infusion, Laura Matuszewska, Caitlynn Cooper, Victoria Sattarova, Wassef Chanbour, Evan Meyer, Vania Rashidi

Student Publications

Purpose

To report a case of bilateral corneal pseudomicrocysts associated with infusions of a novel antibody-drug conjugate targeting claudin-6, called TORL-1-23.

Observations

A 47-year-old female with a history of advanced recurrent serous ovarian cancer presented to a level 1 tertiary care center with ocular irritation, redness, tearing, and light sensitivity following two infusions of TORL-1-23. Patient's past ocular history was unremarkable. The patient was enrolled in a phase 1 clinical trial for TORL-1-23, an antibody-drug conjugate (ADC). Nine days following the second infusion the patient presented to the ophthalmology clinic complaining of two weeks of bilateral eye discomfort, tearing, and …


Enhancing Hip And Knee Arthroplasty Outcomes With Immunonutrition: A Review Of The Evidence, Kyle Taylor, Winifred Chijoke, Quinci Howard, Sandra Messiha, Jocelyn Hunt, Bernice Diaz, Hamza Khalid, Janae Rasmussen Sep 2025

Enhancing Hip And Knee Arthroplasty Outcomes With Immunonutrition: A Review Of The Evidence, Kyle Taylor, Winifred Chijoke, Quinci Howard, Sandra Messiha, Jocelyn Hunt, Bernice Diaz, Hamza Khalid, Janae Rasmussen

Student Publications

Total hip and knee arthroplasty are common surgical procedures aimed at improving mobility and quality of life. Despite surgical advances, postoperative complications remain a concern, particularly for patients with comorbidities and poor nutritional status. Immunonutrition, the targeted administration of nutrients that modulate inflammation, such as arginine, omega-3 fatty acids, and antioxidants, has been shown to reduce infections, complications in wound healing, and shorten hospital length of stay. This review examines current evidence on the role of immunonutrition in hip and knee arthroplasty, focusing on the mechanisms of key nutrients, clinical application of supplementation, and areas for future investigation. Despite promising …


Drivers Of Frequent Emergency Department Use In Socioeconomically Disadvantaged Older Adults: A Qualitative Study, Elise Brickhouse, Mariana Rios, Aanand D Naik, Margaret Samuels-Kalow, Naomi George Sep 2025

Drivers Of Frequent Emergency Department Use In Socioeconomically Disadvantaged Older Adults: A Qualitative Study, Elise Brickhouse, Mariana Rios, Aanand D Naik, Margaret Samuels-Kalow, Naomi George

Faculty, Staff and Student Publications

Background: The emergency department (ED) is the safety net for and a common point of healthcare access for socioeconomically disadvantaged older adults. Little is known about socioeconomically disadvantaged older ED patients' perspectives on their health, healthcare access, and ED use. Such insights could guide tailored interventions to address unmet clinical and health-related social needs (HRSN).

Methods: We performed a qualitative study with older adults in a single public safety net hospital ED. We interviewed patients age 60+ who had ≥ 4 ED 4 visits in the past year. Semi-structured interviews explored perceived health needs and motivations underlying ED visits. We …


Chest X-Ray Interpretation In The Epico Pediatric Covid-19 Study: Addressing Misconceptions, Daniela Duarte-Montero, María Margarita Rodriguez, Arianna Martinez, Paola Sanchez, Carolina Tovar, Gabriela Friedrich, Gustavo Adolfo Triana-Rodriguez, Mónica Royero-Arias, Jessica Echeverry, Tamara Gamo, Luz Ángela Moreno, Olga Lucía Baquero, Luz Marina Mejía, Sonia Restrepo-Gualteros, Sergio Moreno-Lopez, Juan Gabriel Piñeros, Carlos Álvarez-Moreno, Alejandro Díaz-Díaz, Clara Galvis-Diaz, José Manuel Nieto, Irati Gastesi, Cinta Moraleda, Alfredo Tagarro García, Andrea Ramirez Varela, Epico‐Colombia And Epico‐Aep Working Groups Sep 2025

Chest X-Ray Interpretation In The Epico Pediatric Covid-19 Study: Addressing Misconceptions, Daniela Duarte-Montero, María Margarita Rodriguez, Arianna Martinez, Paola Sanchez, Carolina Tovar, Gabriela Friedrich, Gustavo Adolfo Triana-Rodriguez, Mónica Royero-Arias, Jessica Echeverry, Tamara Gamo, Luz Ángela Moreno, Olga Lucía Baquero, Luz Marina Mejía, Sonia Restrepo-Gualteros, Sergio Moreno-Lopez, Juan Gabriel Piñeros, Carlos Álvarez-Moreno, Alejandro Díaz-Díaz, Clara Galvis-Diaz, José Manuel Nieto, Irati Gastesi, Cinta Moraleda, Alfredo Tagarro García, Andrea Ramirez Varela, Epico‐Colombia And Epico‐Aep Working Groups

Faculty, Staff and Student Publications

No abstract provided.


Steroid Hormone Biosynthesis And Dietary Related Metabolites Associated With Excessive Daytime Sleepiness, Robert Kaplan, Kent D Taylor, Peter Y Liu, Satu J Strausz, Hanna M Ollila, Tianyi Huang, Russell P Tracy, Craig Johnson, Stephen S Rich, Clary B Clish, Jerome I Rotter, Susan Redline, Tamar Sofer, Heming Wang Sep 2025

Steroid Hormone Biosynthesis And Dietary Related Metabolites Associated With Excessive Daytime Sleepiness, Robert Kaplan, Kent D Taylor, Peter Y Liu, Satu J Strausz, Hanna M Ollila, Tianyi Huang, Russell P Tracy, Craig Johnson, Stephen S Rich, Clary B Clish, Jerome I Rotter, Susan Redline, Tamar Sofer, Heming Wang

Faculty, Staff and Student Publications

Background: Excessive daytime sleepiness (EDS) is a complex sleep problem that affects approximately 33% of the United States population. Although EDS usually occurs in conjunction with insufficient sleep and other sleep and circadian disorders, recent studies have shown unique genetic markers and metabolic pathways underlying EDS. Here, we aimed to further elucidate the biological profile of EDS using large-scale single- and pathway-level metabolomics analyses.

Methods: Metabolomics data were available for 877 metabolites in 6071 individuals from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). EDS was assessed using the Epworth Sleepiness Scale (ESS) questionnaire. We performed linear regression for each …


A Metabolomics Study Of Cardiac Dysfunction In Hyperglycemia: Findings From The Atherosclerosis Risk In Communities (Aric) Study And The Hispanic Community Health Study/Study Of Latinos (Hchs/Sol), Hicham Skali, Christie Ballantyne, Elizabeth Selvin, Amil Shah, Robert Kaplan, Carlos J Rodriguez, Qibin Qi, Susan Cheng, Bing Yu Sep 2025

A Metabolomics Study Of Cardiac Dysfunction In Hyperglycemia: Findings From The Atherosclerosis Risk In Communities (Aric) Study And The Hispanic Community Health Study/Study Of Latinos (Hchs/Sol), Hicham Skali, Christie Ballantyne, Elizabeth Selvin, Amil Shah, Robert Kaplan, Carlos J Rodriguez, Qibin Qi, Susan Cheng, Bing Yu

Faculty, Staff and Student Publications

Objective: Hyperglycemic states (prediabetes and diabetes) are associated with heart failure (HF) risk. We aimed to identify distinct metabolites for subclinical cardiac dysfunction, a precursor of HF, in hyperglycemic or euglycemic individuals.

Research design and methods: We conducted cross-sectional and prospective analyses of 2,492 HF-free participants from the Atherosclerosis Risk in Communities (ARIC) study visit 5, 2011-2013. A total of 1,297 participants were hyperglycemic (assessed on the basis of hemoglobin A1c >5.7%, fasting glucose >100 mg/dL, use of diabetes medication, or diagnosis), and 1,195 were euglycemic. We used logistic regression for analysis of association between 790 metabolites and cardiac dysfunction, …


Social Determinants Of Health In Lesbian, Gay, Bisexual, Transgender, Queer, And Other Sexual And Gender Minority (Lgbtq+) Older Adults: Impact Of Socioeconomic Disadvantage On Inpatient Hospitalizations, Jennifer T. May Phd, Rn, Anp-Bc, Devon Noonan, Susan G. Silva Sep 2025

Social Determinants Of Health In Lesbian, Gay, Bisexual, Transgender, Queer, And Other Sexual And Gender Minority (Lgbtq+) Older Adults: Impact Of Socioeconomic Disadvantage On Inpatient Hospitalizations, Jennifer T. May Phd, Rn, Anp-Bc, Devon Noonan, Susan G. Silva

Publications

Introduction Little is known about the impact of socioeconomic disadvantage on lesbian, gay, bisexual, transgender, queer, and other sexual and gender minority (LGBTQ+) older adults (≥50 years). The aim of this study is to determine whether the distribution of LGBTQ+ inpatient hospitalizations are related to structural socioeconomic factors. Methods A secondary analysis of retrospective electronic health record data for LGBTQ+ older adults hospitalized from 2018 to 2022 was conducted at one large health system. The average county area deprivation index where the patient resided was calculated. Results The analysis included 2270 LGBTQ+ older adult inpatient hospitalizations, with 1508 (66.4%) from …


Wind Turbine Rotor Design Using High-Fidelity Aerostructural Optimization, Marco Mangano, Sicheng He, Yingqian Liao, Denis-Gabriel Caprace, Andrew Ning, Joaquim R. R. A. Martins Sep 2025

Wind Turbine Rotor Design Using High-Fidelity Aerostructural Optimization, Marco Mangano, Sicheng He, Yingqian Liao, Denis-Gabriel Caprace, Andrew Ning, Joaquim R. R. A. Martins

Faculty Publications

Large wind turbines yield more energy but demand careful aeroelastic blade design. Coupled multiphysics design strategies can reduce wind energy costs exploiting fluid-structure interactions. This work presents the first high-fidelity aerostructural optimization study of a large wind turbine rotor.We use blade-resolved fluid dynamics and structural solvers in a monolithic gradient-based optimization framework to explore steady-state torque and blade mass trade-offs. The coupled-adjoint approach computes gradients efficiently, enabling the optimization of over 100 structural and geometric parameters simultaneously. Our optimization study modifies a DTU 10 MW benchmark with a simplified structure and isotropic material properties. The tightly coupled optimizations increase torque …


A Fascination With Gastrointestinal Viruses Sep 2025

A Fascination With Gastrointestinal Viruses

Faculty, Staff and Students Publications

My arrival into this world came quickly, according to my mother, and it feels like my life has mirrored that rapid beginning. I have enjoyed a rich, varied, and stimulating life and career that have gone through several phases. I credit genetics, my family, technological advances, and many environmental factors for shaping my career. Being a virologist allowed me to be curious and creative and to make several unexpected discoveries. This has been a fun and rewarding journey, but it wasn't always easy. I am not accustomed to talking about myself, but I am happy to share some scientific achievements …