Digital Commons Network^™

Research On Geological Complications Occurring During Drilling Operations At Uzbekneftegaz Jsc Wells, Otabek Rajabovich Eshmurodov, Komilxodja Anvarxodjayevich Raximov, Shaxnoza Hikmatullayevna Mirsaatova, Tolib Olimovich Komilov, Sherali Halloqovich Umedov

Technical science and innovation

This article presents an analysis of maintaining wellbore stability, preventing pack-off formation, stuck pipe incidents, and drilling fluid losses. A technology aimed at ensuring successful and high-quality trouble-free well drilling is analyzed and recommended. Based on data obtained from the Surkhandarya Basin fields, many wells were not drilled to the designed depth. Geophysical data from studied fields indicate that pore pressure retained in clay formations causes wellbore instability. These data also help to identify zones prone to collapse; however, the direct measurement of pore pressure in such formations remains impossible. This research was primarily conducted in the Ustyurt region, one …

Technical And Economic Justification Of The New Design Of A Hydro-Accumulation Syste, Kurbon Salikhdjanovich Dzhuraev, Abdurasul Sayfutdinov, Elyor Doniyorovich Ismoilov

Technical science and innovation

The effective utilization of renewable energy sources such as solar and wind requires reliable and efficient energy storage systems due to their irregular and intermittent supply. This paper presents a novel hydro-accumulation system that significantly reduces energy consumption by integrating hydraulic ram pumps instead of traditional electrically powered pumps. The proposed system operates in cascade mode, where the kinetic energy of water is used multiple times through a sequence of hydraulic rams to pump water from a lower reservoir back to the upper one. Each stage of the system reuses the outflow water of the previous ram, achieving up to …

Introduction To Sociology: Socialization, Dr. Marcia Morrison Ph.D.

Open Educational Resources

Abstract

This paper offers a comprehensive examination of socialization and identity development through a comparative lens, focusing on American, Chinese, and Japanese cultures. It explores how distinct cultural values—individualism, loyalty, and cooperation—shape personal and collective identities from childhood through old age. Utilizing the life course perspective, the analysis considers how factors such as generation, socioeconomic status, race, and gender influence the trajectory of human development. The evolution of childhood is traced across historical and cultural contexts, highlighting shifting perceptions, the impact of industrialization on children's roles, and the persistent influence of class and ethnicity on access to education and well-being. …

Pan-Cancer Immune And Stromal Deconvolution Predicts Clinical Outcomes And Mutation Profiles, Bhavneet Bhinder, Sunantha Sethuraman, R Jay Mashl, Li Ding, Matthew H Bailey, Daniel Cui Zhou, Et Al.

2020-Current year OA Pubs

Traditional gene expression deconvolution methods assess a limited number of cell types, therefore do not capture the full complexity of the tumor microenvironment (TME). Here, we integrate nine deconvolution tools to assess 79 TME cell types in 10,592 tumors across 33 different cancer types, creating the most comprehensive analysis of the TME. In total, we found 41 patterns of immune infiltration and stroma profiles, identifying heterogeneous yet unique TME portraits for each cancer and several new findings. Our findings indicate that leukocytes play a major role in distinguishing various tumor types, and that a shared immune-rich TME cluster predicts better …

Communication Enhancement Strategies To Mitigate Functional Siloes In Head Start Programs, Maryom G. Mccloud

Walden Dissertations and Doctoral Studies

Inefficient internal communication between program and financial operations may negatively affect organizational performance and profitability. Some Head Start Program (HSP) leaders are concerned with communication failures because of the potential to negatively impact business productivity and profitability. Grounded in business process re-engineering, the purpose of this qualitative single case study was to explore strategies used by HSP leaders to increase communications between program and financial operations to increase profitability. The participants were four HSP leaders located in the Northern Region of the United States, who successfully implemented such strategies. Data were collected from semistructured interviews and company documents. Through thematic …

Neural Associations Between Fingerspelling, Print, And Signs: An Erp Priming Study With Deaf Readers, Brittany Lee, Sofia E. Ortega, Priscilla M. Martinez, Katherine J. Midgley, Phillip J. Holcomb, Karen Emmorey

Communication Sciences and Disorders Faculty Articles and Research

Fingerspelling is a leading predictor of reading ability for deaf people who use a signed language, but few neuroimaging studies have examined how it supports reading. We used event-related potentials to investigate how fingerspelled words prime printed words. Twenty-four skilled deaf adult readers completed a Go/No-Go task while viewing printed English word targets following related and unrelated primes in one of three conditions: printed English words, American Sign Language (ASL) signs, and fingerspelled words. N400 priming effects were strong across all three conditions. Early N400 effects were similar for printed word primes and fingerspelled word primes, suggesting shared orthographic representations. …

Comparative Analysis Of Gas And Mechanical Emissions From Electric Cars And Internal Combustion Engine Vehicles, Bakhtiyor Akhmatjonovich Kosimov

Technical science and innovation

This article analyzes the environmental impact of modern cars, in particular the amount of harmful substances emitted into the environment by electric cars and internal combustion engine cars, and provides scientific information on the substances that are released from cars in the form of not only gaseous emissions, but also dust particles generated by the mechanical wear of the brake system and tires. At the same time, this article also takes a scientific approach to the wear rates of brake pads and tires, their impact on environmental safety, and the level of dispersion of the microdust generated. Comparative tables have …

Improving The Methodology Of Complex Organization Of Rural Areas Based On Gis Technologies, Anvarjon Pardaboyev

Technical science and innovation

In the world, scientific research is being conducted aimed at improving the efficiency of complex organization of rural areas by utilizing modern geographic information systems (GIS) and remote sensing data. These studies focus on shaping the land allocated to these areas, organizing their activities, and forming the basis of cartographic information. Additionally, the use of modern GIS and remote sensing data has become widespread in the complex organization of rural areas in many countries. This method stands out for its effectiveness in organizing regions today.

In our republic, comprehensive measures are being implemented to consistently develop production through structural, institutional, …

Intelligent Control Of Reducing Energy Consumption And Water Loss In Smart Home Systems, Hakimjon Nasriddinovich Zaynidinov, Damira Farxodovna Hodjaeva, Dhananjay Singh

Technical science and innovation

The article presents an innovative approach to developing an intelligent control system for managing temperature and water level in smart home systems. The proposed method integrates an adaptive PID controller with fuzzy logic algorithms, enabling dynamic adjustment of the PID controller coefficients in real time. The mathematical model of the system incorporates heat balance equations, differential heat transfer relations, and nonlinear models of fluid loss. The adaptive control algorithms developed within the study allow the system to effectively respond to changes in input data.

A comprehensive analysis of the membership functions is conducted, along with adaptive tuning of the PID …

Research Into Technological Features In The Curring Process Of Multilayer Polymer Composite Parts, Umidbek Dilshod Ugli Kosimov, Jonibek Kobilovich Tokhirov, Andrey Dmitrievich Novikov

Technical science and innovation

This paper examines the main technologies and mechanisms used in the curing process of multilayer thick-walled parts of unmanned aerial vehicles (UAVs) made of polymer composite materials (PCM) based on epoxy resin. The study provides a detailed analysis of the technological features of the curing process, its kinetics, and the influence of heat transfer mechanisms on the final quality of molded components. It is emphasized that due to the low thermal conductivity of PCM, temperature inhomogeneity may occur during curing, leading to defects, internal stresses, and deterioration of the mechanical properties of the product. Therefore, ensuring uniform temperature distribution throughout …

The Scylla And Charybdis Of Paternalism And Moral Complicity, J.L.A. Donohue

Philosophy Faculty Publications and Presentations

In some circumstances avoiding complicity seems to require acting paternalistically, while avoiding paternalism seems to require moral complicity in another's wrongful projects. In order to solve the conflict we will need to investigate the concepts of paternalism and moral complicity and, more importantly, our moral interest in them in the first place. Why do the wrongs of paternalism and moral complicity matter to us? And what does this tell us about what it means to set out to treat others well, where that includes both respecting their agency and helping them to act rightly? I will suggest that adopting a …

Evaluation Of Different Resin-Based Barriers In Reducing Microleakage In Restoratively Compromised Posterior Teeth During Rubber Dam Isolation: An Ex Vivo Study, Carolina Becerra, Albert F. Mcmullen Iii, Joon Koh, Thomas E. Lallier

School of Dentistry Faculty Publications

Introduction: The rubber dam has been a standard in endodontic practice for over 140 years, providing critical isolation to prevent microbial contamination during root canal therapy. However, studies indicate that microleakage between the rubber dam and tooth structure may still occur, potentially leading to bacterial infiltration. Various resin-based barriers have been introduced to enhance isolation and minimize leakage. This study aimed to evaluate the efficacy of four resin-based barriers in reducing microleakage during endodontic procedures. Methods: Forty extracted human mandibular molars were selected, stored in distilled water, and standardized for experimental conditions. Standard endodontic access was created, and the mesiobuccal …

An Optimized Model For Identification Of Cerebral Palsy Using Deep Learning, Anjar Ahsan, Hassan Bin Mohammed, Abhilash Maroju, Nurhafizah Moziyana Mohd Yusop, Wan Su Emi Yusnita Wan Yusof, Najjah Salwa Abd Razak, Mohd Arif Dar

Polytechnic Journal

Cerebral palsy (CP), a neurological disorder that affects children and can occasionally result in cognitive problems as well as deficits in motor function can be caused by prenatal, perinatal, or postnatal factors. Each subtype of cerebral palsy (CP), such as spastic and non-spastic cerebral palsy, has distinct symptoms based on the location of the brain lesion and how it affects muscle tone. Individualized therapy and rehabilitation programs are necessary to treat these differences effectively. Therefore, early-stage CP categorization is crucial to ensuring timely and targeted treatment efforts. The functional magnetic resonance imaging (fMRI) of the infant's brain is a helpful …

Pharmacological Considerations For Healthcare Providers When Caring For Muslim Patients: A Practical Guide, Layla Abubshait, Nissa Tasnim, Taha Cangoz

Einstein Health Papers

Healthcare providers increasingly encounter Muslim patients with unique pharmacological considerations influenced by religious beliefs and practices. Islam, as the world's second-largest religion, includes specific guidelines affecting medication permissibility, particularly regarding alcohol and pork-derived ingredients. This educational guide examines the intersection of Islamic teachings with pharmacotherapy, providing examples of commonly prescribed medications containing alcohol or porcine-derived gelatin from our academic medical center's inpatient and outpatient formulary. We document alcohol content percentages in various medications and suggest possible alternatives as illustrative examples. Most importantly, we present a step-by-step practical framework for using National Drug Code (NDC) numbers and the DailyMed database, enabling …

Mic: A Deep Learning Tool For Assigning Ions And Waters In Cryo-Em And Crystal Structures, Laura Shub, Wenjin Liu, Georgios Skiniotis, Michael J Keiser, Michael J Robertson

Faculty, Staff and Students Publications

At sufficiently high resolution, x-ray crystallography and cryogenic electron microscopy are capable of resolving small spherical map features corresponding to either water or ions. Correct classification of these sites provides crucial insight for understanding structure and function as well as guiding downstream design tasks, including structure-based drug discovery and de novo biomolecule design. However, direct identification of these sites from experimental data can prove challenging, and existing empirical approaches leveraging the local environment can only characterize limited ion types. We present a representation of chemical environments using interaction fingerprints and develop a machine learning model to predict the identity of …

Human Extravillous Trophoblasts Require Src-2 For Sustained Viability, Migration, And Invasion, Vineet K Maurya, Pooja Popli, Bryan C Nikolai, David M Lonard, Ramakrishna Kommagani, Bert W O'Malley, John P Lydon

Faculty, Staff and Students Publications

Defective placentation is a recognized etiology for several gestational complications that include early pregnancy loss, preeclampsia, and intrauterine growth restriction. Sustained viability, migration, and invasion are essential cellular properties for embryonic extravillous trophoblasts to execute their roles in placental development and function, while derailment of these cellular processes is linked to placental disorders. Although the cellular functions of extravillous trophoblasts are well recognized, our understanding of the pivotal molecular determinants of these functions is incomplete. Using the HTR-8/SVneo immortalized human extravillous trophoblast cell line, we report that steroid receptor coactivator-2 (SRC-2), a coregulator of transcription factor-mediated gene expression, is essential …

Experiences Of Managing And Living With Autoimmune Addison’S Disease In The Younger And Newly Diagnosed Adults: An Interpretative Phenomenological Analysis, Mathew Horodner

Walden Dissertations and Doctoral Studies

There is a lack of knowledge regarding the experiences of managing and living with autoimmune Addison’s disease (AD) in the younger and newly diagnosed adults. AD research usually focuses on biological or medication studies. Thus, the purpose of this qualitative study was to understand the lived experiences of the younger and newly diagnosed adults living with autoimmune AD. Consisting of the complex integration of biological, psychological, and social factors, Engel’s biopsychosocial model served as the study’s conceptual framework. I conducted this study to include the experiences of managing and living with autoimmune AD in the younger (18–35) and newly diagnosed …

8-Page Zine Extra Credit Assignment, Ricaute Rogers

Open Educational Resources

This is an 8-page minizine extra credit assignment that put into practice the concepts learned in CIS100.

Factors Associated With Falls Among Nursing Home Residents, Dorsenia Hendrix

Walden Dissertations and Doctoral Studies

Falls in nursing home facilities are prevalent, and numbers continue to rise as residents grow older and antipsychotic (AP) medications are prescribed more frequently. The purpose of this quantitative study was to investigate whether frequency of falls was related to the use of AP medications. Data (N=100) were collected from 2020 incident reports, investigation sheets, and patient charts generated by the State Department of Public Health regarding resident falls and the use of AP medications in a nursing home Facility located in the Southern United States. Social Cognitive Theory (SCT) was used to understand specific behavior patterns such as personal, …

Staff Education On Colorectal Cancer Screening To Improve Knowledge And Usage, Mary Tessie Thullah Bangura

Walden Dissertations and Doctoral Studies

Executive Summary: Staff Education Project Staff Education on Colorectal Cancer Screening to Improve Knowledge and Usage

Staff Education Project: Staff Education To Improve Nurses’ Knowledge, Self-Efficacy, And Motivation In Supporting Medication Adherence, Giovanna Happy

Walden Dissertations and Doctoral Studies

Medication nonadherence among individuals with psychiatric disorders remains a significant barrier to recovery, ranging from 40% to 60%. Contributing factors include fear of side effects, stigma, cognitive limitations, and complex regimens. This staff education project addressed challenges through the implementation of a structured, evidence-based intervention to improve adherence-supportive practices among 14 outpatient psychiatric nurses. A preimplementation needs assessment revealed inconsistent application of adherence strategies and low staff confidence. The project’s objective was to evaluate whether a structured education program could improve nurses’ knowledge by 15%, confidence by 15%, and willingness by 3.5 points on a Likert scale to promote medication …

Big Five Personality Traits As Predictors Of Funeral Directors’ Job Satisfaction, Teresa Busick

Walden Dissertations and Doctoral Studies

By 2037, annual deaths in the United States are expected to exceed 3.6 million, over 1 million more than in 2015. At the same time, the funeral service industry faces a serious staffing problem, with about 50% of funeral directors leaving the profession within 2 years. These combined challenges highlight the need to understand what contributes to job satisfaction and helps to retain these workers in this essential field. This quantitative correlational study examined whether the Big Five personality traits predict job satisfaction among funeral directors. Thus, the Big Five model of personality traits was used to guide the study. …

Strategies Used By Public Relations And Communications Executives To Implement Ethical Use Standards For Ai, Karl Bateson

Walden Dissertations and Doctoral Studies

Public relations and communications (PR&C) executives’ ineffective artificial intelligence (AI) strategies to develop and apply ethical frameworks for AI implementation can negatively impact organizations’ brand reputation. Grounded in AI4People and stakeholder theory, the purpose of this qualitative pragmatic inquiry project was to identify and explore the effective AI strategies PR&C executives used to develop and apply ethical frameworks for AI implementation while maintaining their organizations’ brand reputations. The participants were six PR&C executives who used effective strategies to develop and apply ethical frameworks for AI implementation while maintaining their organization’s brand reputation. Data were collected using semistructured interviews, public websites, …

An Action Research Study On Ai Video Vs. Written Feedback: Enhancing Undergraduate Academic Writing And Critical Thinking, Sandra Baroudi, Nida Mubeen, Suha Karaki

All Works

This action research explores how AI-assisted feedback formats influence students’ academic writing and critical thinking, a gap particularly relevant in the digital learning landscape. This study involved 40 undergraduate Emirati students divided into two groups, receiving either AI-generated video or written feedback across three assignments. Using a quantitative design, data were gathered using standardized critical thinking and academic writing skills rubrics. Additionally, students completed post-surveys to capture their perceptions, engagement levels and use of AI tools in the learning process. Results showed written feedback significantly improvemed critical thinking (M = 2.80, SD = 0.75) compared to video feedback (M = …

Cortical Functional Organization In Early Childhood, Jiaxin Tu

Arts & Sciences Graduate Student Theses and Dissertations

The advent of connectivity-based methods, particularly those utilizing spontaneous BOLD signals, has significantly advanced brain mapping and deepened our understanding of the human brain's functional architecture. While prior research has explored functional organization in early childhood, most studies have focused on coarse, group-level distinctions aligned with adult literature, often within narrow age ranges. This dissertation extends these investigations by examining cortical functional organization in greater detail among healthy infants and toddlers aged 1 to 5 years. Chapter 1 employs spontaneous BOLD signals in sleeping infants and toddlers to derive a group-level functional organization at the resolution of areas and networks. …

Chaperone-Usher Pathway Pili Adhesin Conformations And Inhibitors In Urinary Tract Infections, Edward Lopatto

Arts & Sciences Graduate Student Theses and Dissertations

Antibiotic resistant bacteria are becoming increasingly difficult-to-treat resulting in increased morbidity and mortality, especially for common infections such as urinary tract infections (UTIs). Globally, UTIs afflict over 400 million people a year. Numerous different gram-negative and gram-positive bacterial species cause UTIs, including uropathogenic Escherichia coli (UPEC), Klebsiella pneumoniae, and Acinetobacter baumannii. Many of these bacterial species are listed as pathogens of urgent concern by the Center for Disease Control due to the dangerous rise and prevalence of antibiotic resistance necessitating development of new therapeutic measures. Bacteria utilize adhesin factors, such as chaperone-usher pathway (CUP) pili to gain a foothold in …

Vigorous Physical Activity As A Potential Environmental Risk Factor In Renal Medullary Carcinoma, Daniel D Shapiro, Sagar S Mukhida, Andrew W Hahn, Ayman Isahaku, Schyler M Turner, Jessica P Cheng, Pankaj K Chauhan, Susan S Thomas, Beei Chan, Zita D Lim, Nizar M Tannir, Maria Chang Swartz, Pavlos Msaouel

Faculty, Staff and Student Publications

Purpose: Renal medullary carcinoma (RMC) is a rare but aggressive kidney cancer affecting young individuals with sickle hemoglobinopathies. Prior retrospective case-control and mouse modeling studies suggest a mechanism linking vigorous intensity physical activity to increased RMC risk in individuals with sickle hemoglobinopathies. This study aimed to prospectively investigate the association between vigorous intensity exercise and RMC.

Materials and methods: This study used a validated questionnaire to prospectively assess reported physical activity in a large cohort of patients with RMC compared to the activity of individuals without RMC. Between 2022 and 2024, patients with RMC (N = 39) were prospectively surveyed …

Pan-Cancer Immune And Stromal Deconvolution Predicts Clinical Outcomes And Mutation Profiles, Bhavneet Bhinder, Verena Friedl, Sunantha Sethuraman, Davide Risso, Kami E Chiotti, R Jay Mashl, Kyle P Ellrott, Jordan A Lee, Christopher K Wong, Kofi Gyan, Aditya Deshpande, Marcin Imielinski, Rohan Bareja, Josh Stuart, Myron Peto, Katherine A Hoadley, Alexander J Lazar, Andrew D Cherniack, Jingchun Zhu, Shaolong Cao, Mark Rubin, Wenyi Wang, Oliver F Bathe, Nicolas Robine, Li Ding, Peter W Laird, Wanding Zhou, Hui Shen, Vésteinn Thorsson, Jen Jen Yeh, Matthew H Bailey, Daniel Cui Zhou, Xianlu L Peng, Mary Goldman, Yongsheng Li, Anil Korkut, Nidhi Sahni, D Neil Hayes, Michael K A Mensah, Ina Felau, Anab Kemal, Samantha Caesar-Johnson, John A Demchok, Liming Yang, Martin L Ferguson, Roy Tarnuzzer, Zhining Wang, Jean C Zenklusen, Paul Spellman, Olivier Elemento

Faculty, Staff and Student Publications

Traditional gene expression deconvolution methods assess a limited number of cell types, therefore do not capture the full complexity of the tumor microenvironment (TME). Here, we integrate nine deconvolution tools to assess 79 TME cell types in 10,592 tumors across 33 different cancer types, creating the most comprehensive analysis of the TME. In total, we found 41 patterns of immune infiltration and stroma profiles, identifying heterogeneous yet unique TME portraits for each cancer and several new findings. Our findings indicate that leukocytes play a major role in distinguishing various tumor types, and that a shared immune-rich TME cluster predicts better …

Supporting Patients With Advanced Cancer And Their Spouses In Parenting Minor Children: Results Of A Randomized Controlled Trial, Kathrin Milbury, Sujin Ann-Yi, Meagan S Whisenant, Morgan Jones, Yisheng Li, Victoria Necroto, Sania D Yousuf, Mariana Chavez-Macgregor, Larrisa Meyers, Eduardo Bruera

Faculty, Staff and Student Publications

Introduction: Patients with advanced cancer and their spousal caregivers who parent minor children report unmet parenting concerns and increased psychological distress. Seeking to address these important supportive care needs, this RCT examined the feasibility, acceptability, and initial evidence for the efficacy of a novel psychosocial intervention.

Patients and methods: Patients with a metastatic solid malignancy and their spouses completed self-reported validated assessments of psychological symptoms and cancer-related parenting outcomes and were then randomized to the parent support intervention or a usual care (UC) group. Both groups were reassessed 6 and 12 weeks later. Dyads randomized to the counselor-led intervention attended …

Improving Genetics Equity: Identifying Women Eligible For Genetic Care Services Using Mammography Clinics In Underserved Areas As Screening Hubs, Darya Kizub, Rachel Bluebond, Sierra Green, Jessica Duckworth, Sreejesh Shanker, Autumn Vara, Banu Arun

Faculty, Staff and Student Publications

PURPOSE: Fewer than 20% of underserved individuals undergo guideline-concordant hereditary breast and ovarian cancer (HBOC) genetic testing (GT). Our study aimed to determine the proportion of women eligible for HBOC GT using a cancer genetics risk assessment (CGRA) tool at breast cancer (BC) screening clinics in underserved communities and to describe the program's impact.

METHODS: Participants were women who presented for BC screening at The Rose clinics, serving low-income underserved communities in southeast Texas, and completed the CGRA. High-risk individuals received bilingual educational materials and a saliva-based GT kit. Those with a pathogenic variant (PV) or a variant of uncertain …