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Articles 148801 - 148830 of 5149721
Full-Text Articles in Entire DC Network
Botulinum Toxin For The Treatment Of Tremors, Steven Bellows, Joseph Jankovic
Botulinum Toxin For The Treatment Of Tremors, Steven Bellows, Joseph Jankovic
Faculty, Staff and Students Publications
Tremor, an oscillatory movement disorder, is commonly encountered in clinical practice in the setting of a variety of etiologies, such as essential tremor and Parkinson's disease. Despite its high prevalence, treatment options are somewhat limited. Oral medications are often ineffective or limited by side effects, and other treatments, such as deep brain stimulation, are more invasive and costly. Botulinum toxin (BoNT) injections are a well-established therapy in the treatment of dystonia, but its use in the treatment of tremors has not been fully explored. In this review, we discuss the available randomized controlled trials and open-label evidence for the use …
Neighborhood Socioeconomic Status And Overall Survival Among Children With Acute Lymphoblastic Leukemia, Anna Hoppmann, Debroah M. Hurley, Stuart Cramer, Monique J. Brown Ph.D., Mph
Neighborhood Socioeconomic Status And Overall Survival Among Children With Acute Lymphoblastic Leukemia, Anna Hoppmann, Debroah M. Hurley, Stuart Cramer, Monique J. Brown Ph.D., Mph
Faculty Publications
A disadvantaged neighborhood, as represented by area-level socioeconomic status (SES) has been associated with adverse outcomes among children with acute lymphoblastic leukemia (ALL) in the US, but the duration of impact after ALL diagnosis is not well understood. This retrospective cohort study utilized the National Cancer Database (NCDB) to examine the impact of area-level SES on overall survival among children with ALL. Median income and education quartiles based on residential zip code were used to create a composite area-level SES variable. Individual-level variables included age, sex, race, year of diagnosis, primary payer, distance to care, rurality, time to treatment, and …
Protecting Sleep To Reduce Delirium In Patients 65 Years And Older In The Icu, Jessica L. Thomas
Protecting Sleep To Reduce Delirium In Patients 65 Years And Older In The Icu, Jessica L. Thomas
Doctor of Nursing Practice Final Project Abstract
Protecting Sleep to Reduce Delirium in Patients 65 Years and Older in the ICU
PURPOSE
This quality improvement (QI) project aimed to reduce the incidence of delirium by 30% through a nurse-initiated, non-pharmacological sleep improvement protocol in the ICU.
BACKGROUND
This project was implemented in a large healthcare organization in Houston, Texas, in a 16-bed Intensive Care Unit.
METHODOLOGY
A pre- and post-intervention study was conducted in the ICU over a period using Plan-Do-Study-Act (PDSA) cycles. Baseline delirium (CAM-ICU) and sleep quality (RCSQ) assessments were obtained during Phase 1. Environmental adaptations, such as low lighting, noise reduction, staff education, and …
Accelerating Gnn Inference On Multi-Core Systems, Binglin Ji
Accelerating Gnn Inference On Multi-Core Systems, Binglin Ji
McKelvey School of Engineering Graduate Student Theses & Dissertations
Graph Neural Networks (GNNs) are becoming increasingly popular, with their applications expanding across diverse domains. As the scale of graph data continues to grow, including larger numbers of nodes, edges, and higher embedding dimensions, standardized libraries such as DGL and PyG have been developed to facilitate GNN computation. However, with the rapid increase in the number of processor cores and the evolution of multi-core architectures, these libraries often show poor scalability and fail to execute GNN inference efficiently on the latest multi-core systems, particularly those with upwards of a hundred cores. To address this limitation, we present FGI, a Fast …
An Rna Modification Prevents Extended Codon-Anticodon Interactions From Facilitating +1 Frameshifting, Evelyn M. Kimbrough, Ha An Nguyen, Haixing Li, Jacob M. Mattingly, Nevette A. Bailey, Wei Ning, Howard Gamper, Ya-Ming Hou, Ruben L. Gonzalez, Christine M. Dunham
An Rna Modification Prevents Extended Codon-Anticodon Interactions From Facilitating +1 Frameshifting, Evelyn M. Kimbrough, Ha An Nguyen, Haixing Li, Jacob M. Mattingly, Nevette A. Bailey, Wei Ning, Howard Gamper, Ya-Ming Hou, Ruben L. Gonzalez, Christine M. Dunham
Department of Biochemistry and Molecular Biology Faculty Papers
RNA post-transcriptional modifications act by stabilizing the functional conformations of RNA. While their role in messenger RNA (mRNA) decoding is well established, it is less clear how transfer RNA (tRNA) modifications outside the anticodon contribute to tRNA stability and accurate protein synthesis. Absence of such modifications causes translation errors, including mRNA frameshifting. By integrating single-molecule fluorescence resonance energy transfer and cryogenic electron microscopy, we demonstrate that the N1-methylguanosine (m1G) modification at position 37 of Escherichia coli tRNAProL is necessary and sufficient for modulating the conformational energy of this tRNA on the ribosome so as to suppress +1 frameshifting otherwise induced …
Land8fire: A Complete Study On Wildfire Segmentation Through Comprehensive Review, Human-Annotated Multispectral Dataset, And Extensive Benchmarking, Anh Tran, Minh Tran, Esteban Marti, Jackson Cothren, Chase Rainwater, Sandra Eksioglu, Ngan Le
Land8fire: A Complete Study On Wildfire Segmentation Through Comprehensive Review, Human-Annotated Multispectral Dataset, And Extensive Benchmarking, Anh Tran, Minh Tran, Esteban Marti, Jackson Cothren, Chase Rainwater, Sandra Eksioglu, Ngan Le
Electrical Engineering and Computer Science Faculty Publications and Presentations
Early and accurate wildfire detection is critical for minimizing environmental damage and ensuring a timely response. However, existing satellite-based wildfire datasets suffer from limitations such as coarse ground truth, poor spectral coverage, and class imbalance, which hinder progress in developing robust segmentation models. In this paper, we introduce Land8Fire, a new large-scale wildfire segmentation dataset composed of over 20,000 multispectral image patches derived from Landsat 8 and manually annotated for high-quality fire masks. Building on the ActiveFire dataset, Land8Fire improves ground truth reliability and offers predefined splits for consistent benchmarking. We evaluate a range of state-of-the-art convolutional and transformer-based models, …
Motlow State Community College, August 2025, Tennessee. Comptroller Of The Treasury.
Motlow State Community College, August 2025, Tennessee. Comptroller Of The Treasury.
Financial and Compliance Audit Reports
No abstract provided.
Satellite Passive Ranging Metasurface Optics For Space Rendezvous And Proximity Operations, Zachary Coppens, Cameron Vo, Addison Long, Jeremy Harris
Satellite Passive Ranging Metasurface Optics For Space Rendezvous And Proximity Operations, Zachary Coppens, Cameron Vo, Addison Long, Jeremy Harris
Space Dynamics Laboratory Publications
SDL Presentation on Satellite Passive Ranging Metasurface Optics for Space Rendezvous and Proximity Operations
Digital-Based Nutrition Interventions Employing The Dietary Approaches To Stop Hypertension (Dash) Diet: A Systematic Scoping Review, Elizabeth Dodge, Patricia J. Kelly, Basil H. Aboul-Enein
Digital-Based Nutrition Interventions Employing The Dietary Approaches To Stop Hypertension (Dash) Diet: A Systematic Scoping Review, Elizabeth Dodge, Patricia J. Kelly, Basil H. Aboul-Enein
College of Nursing Faculty Papers & Presentations
Background: The Dietary Approaches to Stop Hypertension (DASH) diet is an internationally recognized anti-hypertensive dietary model. This systematic scoping review examines the effectiveness of digital-based interventions utilizing the DASH dietary pattern. Methods: A search was conducted using 14 databases to include relevant studies from 1997 to January 2025 using PRISMA guidelines for scoping reviews. Results: The review included 24 studies with almost 7000 participants, including randomized controlled trials and cohort studies conducted in several countries. Interventions using the DASH dietary pattern positively affected blood pressure (BP), nutrition behavior, and weight. Some studies also reported secondary outcomes such as reduced healthcare …
How Low A Colorado River Flow To Go? Insights From Numerically Stabilizing Lake Powell And Lake Mead During Crisis, David Rosenberg, Anabelle Myers, Motasem Abualqumboz, Erik Porse
How Low A Colorado River Flow To Go? Insights From Numerically Stabilizing Lake Powell And Lake Mead During Crisis, David Rosenberg, Anabelle Myers, Motasem Abualqumboz, Erik Porse
Civil and Environmental Engineering Faculty Publications
Colorado River users are now discussing dividing river flow on a percentage basis (Fleck, 2025; Hager, 2025, Winslow, 2025). This is an important step to managing a declining and more volatile supply. In our prior May 2025 post, we shared a strategy we have worked on for several years— division of river flow—as one of 13 reasons why we have hope for consensus on Colorado River management. In this post, we address the question: How extreme low river flow and reservoir storage should we plan for going forward (Figure 1)? We also share our insights from numerically stabilizing and recovering …
Kind Kids, Healthy Teens: Child Prosociality And Fruit And Vegetable Intake, Farah Qureshi, Krista P. Woodward, Laura D. Kubzansky, Julia K. Boehm
Kind Kids, Healthy Teens: Child Prosociality And Fruit And Vegetable Intake, Farah Qureshi, Krista P. Woodward, Laura D. Kubzansky, Julia K. Boehm
Psychology Faculty Articles and Research
Introduction
Prosocial behaviors (i.e., being kind, caring, and cooperative) are believed to shape health and well-being starting in childhood. Yet, limited research has examined their long-term impact on health outcomes later in life. This study examined associations between childhood prosocial behaviors and fruit and vegetable consumption patterns across adolescence.Methods
Participants were from the United Kingdom Millennium Cohort Study (N=6,265). Caregivers reported children’s prosocial behaviors using the Strengths and Difficulties Questionnaire at ages 5 (2005–2007), 7 (2007–2009), and 11 (2011–2013) years. In 2024, Poisson regression was conducted to assess the associations between prosocial behaviors at age 5 years and sustained …Coolness, Leisure, And Power : The Development Of Mokanshan Summer Resort In Modern China, 1890–1937, Xuyan Pan
Coolness, Leisure, And Power : The Development Of Mokanshan Summer Resort In Modern China, 1890–1937, Xuyan Pan
Lingnan Theses (MPhil & PhD)
The concept of "coolness" (清涼) embodied fundamentally different bodily and cultural experiences in Chinese and Western traditions. With the introduction of Western-style summer resorts by foreign missionaries in the 1890s, these divergent understandings converged and clashed in new spatial forms. This study examines Mokanshan (莫干山), located in Zhejiang province and recognized as one of the Republican era’s “Four Great Summer Retreats” (民國四大避暑地), as a paradigmatic case of transnational leisure. Initially developed by missionaries as a health-oriented retreat, a transnationally managed enclave, and a nostalgic “overseas home” for expatriates, Mokanshan reflected a hybrid model of modern leisure shaped by foreign institutions. …
Message From The President, Georgia Southern University
Message From The President, Georgia Southern University
Messages from the President
No abstract provided.
Investigating Techniques To Optimise The Layout Of Turbines In A Windfarm Using A Quantum Computer, James Hancock, Matthew Craven, Craig Mcneile, Davide Vadacchino
Investigating Techniques To Optimise The Layout Of Turbines In A Windfarm Using A Quantum Computer, James Hancock, Matthew Craven, Craig Mcneile, Davide Vadacchino
School of Engineering, Computing and Mathematics
This paper investigates Windfarm Layout Optimization (WFLO), where we formulate turbine placement considering wake effects as a Quadratic Unconstrained Binary Optimization (QUBO) problem. Wind energy plays a critical role in the transition toward sustainable power systems, but the optimal placement of turbines remains a challenging combinatorial problem due to complex wake interactions. With recent advances in quantum computing, there is growing interest in exploring whether hybrid quantum-classical methods can provide advantages for such computationally intensive tasks. We investigate solving the resulting QUBO problem using the Variational Quantum Eigensolver (VQE) implemented on Qiskit’s quantum computer simulator, employing a quantum noise-free, gate-based …
Perceptions Of Secondary School Faculty About Vaping Behaviour In Secondary School Students: A Qualitative Analysis In Muscat, Oman, Thamra Al Ghafri, Riyadh Al Siyabi, Rawnaq Al Said, Nihal Afifi, Mohamed Al Harthi, Ahmed Al Harthi
Perceptions Of Secondary School Faculty About Vaping Behaviour In Secondary School Students: A Qualitative Analysis In Muscat, Oman, Thamra Al Ghafri, Riyadh Al Siyabi, Rawnaq Al Said, Nihal Afifi, Mohamed Al Harthi, Ahmed Al Harthi
Sultan Qaboos University Medical Journal
Objectives: The World Health Organization has reported concerns around the increase in vaping behaviour in adolescents. This study aimed to explore the perceptions of the faculty of secondary public schools in Muscat regarding: (a) reasons for vaping among students, (b) impact of this behaviour on school/class dynamics and families and (c) effective interventions within and beyond schools. Methods: This qualitative study held 4 focus groups among secondary school faculty at 4 secondary public schools in the areas of A'Seeb, Al Amarat, Bausher and Muscat in Oman from February to March 2023. Discussions were transcribed verbatim, anonymised and thematically …
Multi-Objective Optimisation Of Floating Offshore Wind Farms Based On A Real-World Case Study, Pawel Manikowski, David Walker, Matthew Craven
Multi-Objective Optimisation Of Floating Offshore Wind Farms Based On A Real-World Case Study, Pawel Manikowski, David Walker, Matthew Craven
School of Engineering, Computing and Mathematics
In this paper, we used real data to predict the position of the floating wind turbines due to three external forces: wind, wave and current. We analysed data provided by energy company Equinor and applied two machine-learning techniques: Multilayer Perceptron and Random Forest. After demonstrating that machine learning models failed, we used a simple linear regression model and optimisation approach to solve the multi-objective optimisation problem. We minimised the perimeter of the wind farm and maximised its power output by applying the multi-objective optimisation algorithm NSGA-II. We also investigated how changing the length of mooring lines affected the optimisation. We …
International Collaboration To Explore Elements For An Effective Residential Childcare Workforce, Justyna Siemionow, Patrick M. Tyler, W. Alex Mason, Deogratias Musoke, Maia Ordonez, Jaime A. Gomez-Blaya, Joseph G. Grzywacz
International Collaboration To Explore Elements For An Effective Residential Childcare Workforce, Justyna Siemionow, Patrick M. Tyler, W. Alex Mason, Deogratias Musoke, Maia Ordonez, Jaime A. Gomez-Blaya, Joseph G. Grzywacz
Faculty Research, Scholarly, and Creative Activity
Residential childcare workers provide critical support to vulnerable children around the world. Building and maintaining a qualified residential childcare workforce is challenged by myriad forces, the foremost of which is recruiting and retaining staff for valuable work often misaligned with available compensation; making individual qualifications at hiring; ongoing training; supervision; and data support systems to monitor performance critical for quality care. This study explored the similarities and differences among these essential elements of staffing across distinct programs: Youth Education Centers (YEC) in Poland, CiudadEscuela Muchachos (CEMU) in Spain, and the Boys Town Family Home Program (BTFHP) in the United States. …
Magnetospectroscopic Studies Of A Series Of Fe(Ii) Scorpionate Complexes: Assessing The Relationship Between Halide Identity And Zero-Field Splitting, Daniel J. Santa Lucia, Laxmi Devkota, Sergey Lindeman, Andrew Ozarowski, J. Krzystek, Mykhaylo Ozerov, Samuel M. Greer, Daniel C. Cummins, Klaus H. Theopold, Mihail Atanasov, Joshua Telser, Adam T. Fiedler
Magnetospectroscopic Studies Of A Series Of Fe(Ii) Scorpionate Complexes: Assessing The Relationship Between Halide Identity And Zero-Field Splitting, Daniel J. Santa Lucia, Laxmi Devkota, Sergey Lindeman, Andrew Ozarowski, J. Krzystek, Mykhaylo Ozerov, Samuel M. Greer, Daniel C. Cummins, Klaus H. Theopold, Mihail Atanasov, Joshua Telser, Adam T. Fiedler
Chemistry Faculty Research and Publications
Ferrous ions in four-coordinate environments are common in protein structures, synthetic catalysts, and molecular magnets. The 3d6 configuration of high-spin Fe(II) imparts an S = 2 ground state, whose analysis using conventional spectroscopic methods is often hindered by substantial zero-field splitting (ZFS). Herein, we provide detailed electronic-structure descriptions for [FeIIX(TptBu,Me)] (1-X; X = F, Cl, Br, I), where (TptBu,Me)− is hydrotris(3-tert-butyl-5-methyl-pyrazol-1-yl)borate. The three pyrazolyl N-donors of the “scorpionate” ligand facially coordinate to Fe(II), giving idealized C3v symmetry with the halide occupying the axial position. Although originally reported …
Spontaneous Closure Of A Patent Processus Vaginalis: A Case Report, Haley Kittle, Amber Lee Geng, Loren Berman, Erin Teeple
Spontaneous Closure Of A Patent Processus Vaginalis: A Case Report, Haley Kittle, Amber Lee Geng, Loren Berman, Erin Teeple
Department of Surgery Faculty Papers
Introduction: Patent process vaginalis and inguinal hernia are prolific in infants, and their repair is a common pediatric surgical procedure. However, there is a paucity of direct evidence detailing the spontaneous closure of patent processus vaginalis.
Case presentation: A 4-month-old boy born prematurely at 34-weeks with low gestational birth weight, underwent laparoscopic gastrostomy tube placement for oropharyngeal dysphagia and was incidentally found to have bilateral patent processes vaginalis. Due to his lack of symptoms, he was managed under the watchful waiting approach. His parents were educated about signs and symptoms of inguinal hernia and were instructed to contact the team …
Keap1 And Stk11/Lkb1 Alterations Enhance Vulnerability To Atr Inhibition In Kras Mutant Non-Small Cell Lung Cancer, Ana Galan-Cobo, Natalie I Vokes, Yu Qian, David Molkentine, Kavya Ramkumar, Alvaro G Paula, Marlese Pisegna, Daniel J Mcgrail, Alissa Poteete, Sungnam Cho, Minh Truong Do, Amirali Karimi, Yifan Kong, Anisha Solanki, Ankur Karmokar, Nicolas Floc'h, Adina Hughes, Rebecca Sargeant, Lucy Young, Li Shen, Gozde Kar, Caezaan Keshvani, Claudio Arrechedera, Sharia Hernandez, Katharina Schlacher, Jing Wang, Sonia Iyer, James Conway, Mohamed Reda Keddar, Marta Milo, Ilario De Toma, Susan E Critchlow, J Carl Barrett, Jan Cosaert, Alan Lau, Viia Valge-Archer, Lauren A Byers, Simon T Barry, John V Heymach
Keap1 And Stk11/Lkb1 Alterations Enhance Vulnerability To Atr Inhibition In Kras Mutant Non-Small Cell Lung Cancer, Ana Galan-Cobo, Natalie I Vokes, Yu Qian, David Molkentine, Kavya Ramkumar, Alvaro G Paula, Marlese Pisegna, Daniel J Mcgrail, Alissa Poteete, Sungnam Cho, Minh Truong Do, Amirali Karimi, Yifan Kong, Anisha Solanki, Ankur Karmokar, Nicolas Floc'h, Adina Hughes, Rebecca Sargeant, Lucy Young, Li Shen, Gozde Kar, Caezaan Keshvani, Claudio Arrechedera, Sharia Hernandez, Katharina Schlacher, Jing Wang, Sonia Iyer, James Conway, Mohamed Reda Keddar, Marta Milo, Ilario De Toma, Susan E Critchlow, J Carl Barrett, Jan Cosaert, Alan Lau, Viia Valge-Archer, Lauren A Byers, Simon T Barry, John V Heymach
Faculty, Staff and Student Publications
KRAS mutations frequently co-occur with alterations in STK11/LKB1 and/or KEAP1, defining an aggressive subset of lung cancers resistant to immuno- and chemotherapy. While LKB1 loss is associated with vulnerability to DNA damage response-based therapies, the impact of KEAP1 alterations remains unknown. We demonstrate that KEAP1-NRF2 pathway drives a compensatory modulation of ATR-CHK1 signaling, enhancing vulnerability to ATR inhibitors (ATRi), particularly in the setting of increased replication stress associated with LKB1 loss. ATRi shows enhanced anti-tumor activity in LKB1 and/or KEAP1-deficient non-small cell lung cancer (NSCLC) models and synergizes with gemcitabine. ATRi also enhances antitumor immunity and mitigates the immunosuppressed phenotype …
Health Outcomes Beyond Age 50 Years In Survivors Of Childhood Cancer: A Report From The Childhood Cancer Survivor Study, Rusha Bhandari, Yan Chen, Eric J Chow, Rebecca M Howell, Lisa B Kenney, Kevin R Krull, Wendy Leisenring, Paul C Nathan, Joseph P Neglia, Kirsten K Ness, Kevin C Oeffinger, Claire Snyder, Lucie M Turcotte, F Lennie Wong, Yutaka Yasui, Gregory T Armstrong, Saro H Armenian
Health Outcomes Beyond Age 50 Years In Survivors Of Childhood Cancer: A Report From The Childhood Cancer Survivor Study, Rusha Bhandari, Yan Chen, Eric J Chow, Rebecca M Howell, Lisa B Kenney, Kevin R Krull, Wendy Leisenring, Paul C Nathan, Joseph P Neglia, Kirsten K Ness, Kevin C Oeffinger, Claire Snyder, Lucie M Turcotte, F Lennie Wong, Yutaka Yasui, Gregory T Armstrong, Saro H Armenian
Faculty, Staff and Student Publications
Purpose: There are limited data on the risk for mortality and health outcomes among the increasing population of older (age >50 years) survivors of childhood cancer during this later stage in life when there is an expected increase in aging-related morbidities.
Methods: We assessed cause-specific mortality, incident new cancers, chronic health conditions (CHCs), frailty, and health status among survivors from the Childhood Cancer Survivor Study, conditional on surviving to 50 years. We calculated conditional survival rates, standardized mortality ratios (SMRs), and, for incident new cancers, cumulative burden, standardized incidence ratios (SIRs), and relative rates (RRs), compared with the general US …
Hippocampal Avoidance During Prophylactic Cranial Irradiation For Patients With Small Cell Lung Cancer: Randomized Phase Ii/Iii Trial Nrg-Cc003, Vinai Gondi, Stephanie L Pugh, Minesh P Mehta, Jeffrey S Wefel, Wolfgang A Tomé, Alexander Y Sun, John Grecula, Kristin J Redmond, Shannon Fogh, Laurie Gaspar, Andre Konski, Joseph Bovi, Clifford G Robinson, Benjamin Corn, Gregory M Videtic, Benjamin H Lok, Harold A Yoon, John H Heinzerling, Albert S Denittis, Ronald C Mcgarry, Kiran Devisetty, Vijayananda Kundapur, Abraham J Wu, Edward C Mccarron, Isabelle Thibault, Edmund L Simon, Andrew M Baschnagel, Samir Narayan, Jondavid Pollock, Rebecca Paulus, Lisa A Kachnic
Hippocampal Avoidance During Prophylactic Cranial Irradiation For Patients With Small Cell Lung Cancer: Randomized Phase Ii/Iii Trial Nrg-Cc003, Vinai Gondi, Stephanie L Pugh, Minesh P Mehta, Jeffrey S Wefel, Wolfgang A Tomé, Alexander Y Sun, John Grecula, Kristin J Redmond, Shannon Fogh, Laurie Gaspar, Andre Konski, Joseph Bovi, Clifford G Robinson, Benjamin Corn, Gregory M Videtic, Benjamin H Lok, Harold A Yoon, John H Heinzerling, Albert S Denittis, Ronald C Mcgarry, Kiran Devisetty, Vijayananda Kundapur, Abraham J Wu, Edward C Mccarron, Isabelle Thibault, Edmund L Simon, Andrew M Baschnagel, Samir Narayan, Jondavid Pollock, Rebecca Paulus, Lisa A Kachnic
Faculty, Staff and Student Publications
Purpose: Hippocampal avoidance (HA) during therapeutic whole-brain radiotherapy reduces the risk of neurocognitive function (NCF) toxicity in patients with brain metastasis. This trial hypothesized that HA during prophylactic cranial irradiation (PCI) in patients with small cell lung cancer (SCLC) leads to noninferior intracranial relapse (ICR) and reduction in NCF toxicity.
Methods: This randomized phase II/III trial enrolled patients with SCLC, no brain metastases, and response to chemotherapy. The primary end points were 12-month ICR (noninferiority design, randomized phase II) and 6-month Hopkins Verbal Learning Test-Revised (HVLT-R) Delayed Recall (DR) failure (phase III). Secondary end points were failure in any NCF …
Post-Pandemic Restaurant Patronage: The Importance Of Neuroticism In Shaping In Person Dining Intentions., Matthew Gorton, Min Yan, Honglyu Lin, Dora Gaćeša Brlić, John White, Ružica Brečić, Ana Tkalac Verčič
Post-Pandemic Restaurant Patronage: The Importance Of Neuroticism In Shaping In Person Dining Intentions., Matthew Gorton, Min Yan, Honglyu Lin, Dora Gaćeša Brlić, John White, Ružica Brečić, Ana Tkalac Verčič
Plymouth Business School
Purpose Even after the lifting of all government restrictions, introduced to combat the spread of Covid-19, many consumers remain fearful of in-person dining. This paper seeks to understand this reticence, and explain post-pandemic restaurant dining intentions. Design/methodology/approach The paper introduces and tests a conceptual framework for understanding in-person dining intentions in the post-Covid-19 era, utilizing structural equation modelling. To empirically validate the model, survey data collection (n = 436) occurred in China after the government lifted its “Zero-Covid” policy. Findings Neuroticism, as a personality trait, negatively affects restaurant trust and increases fear of Covid-19 (threat appraisal), which in turn reduces …
Core Outcome Set And Measures Of Chest Health In Children And Young People With Cerebral Palsy In The Community Setting: The Chesti Study Protocol, Chesti-Study Steering Group, Rachel Knight Lozano, Christopher Morris, Harriet Shannon, Kayleigh Bell, Hugh Malyon, Julia Melluish, Jos Latour, Morag Andrews, Sarah Crombie, Noula Gibson, Samantha Grace, Sian Goddard, Nicola Harman, Sarah Mc Goldrick Kolawole, Laura Lowndes, Paul Mcnamara, Madeline Pilbury, Rachel Rapson, Nicola Scivier, Diane Sellers, Caroline Weighton, Mark Williams, Luana Winston
Core Outcome Set And Measures Of Chest Health In Children And Young People With Cerebral Palsy In The Community Setting: The Chesti Study Protocol, Chesti-Study Steering Group, Rachel Knight Lozano, Christopher Morris, Harriet Shannon, Kayleigh Bell, Hugh Malyon, Julia Melluish, Jos Latour, Morag Andrews, Sarah Crombie, Noula Gibson, Samantha Grace, Sian Goddard, Nicola Harman, Sarah Mc Goldrick Kolawole, Laura Lowndes, Paul Mcnamara, Madeline Pilbury, Rachel Rapson, Nicola Scivier, Diane Sellers, Caroline Weighton, Mark Williams, Luana Winston
School of Health Professions
Introduction Poor chest health is the leading cause of early mortality in children with cerebral palsy (CP). It is also the most common reason to seek healthcare, accruing significant costs and reducing quality-of-life for children and families. Clinical trials examining chest health interventions in CP are characterised by inconsistent outcome measures, limiting the capacity for evidence synthesis to inform clinical application. The study aims to develop a core outcome set (COS) and related measurement instruments to assess, monitor and evaluate chest health in children with CP, both in research and routine clinical practice. The COS will reflect the views of …
Optimization Of Rabbit Urine Liquid Organic Fertilizer And Reduced Npk Fertilizer Doses For Improving Growth And Physiology Of Shallot (Allium Ascalonicum L.), Etik Wukir Tini, Rifqi Raditya Kurniawan
Optimization Of Rabbit Urine Liquid Organic Fertilizer And Reduced Npk Fertilizer Doses For Improving Growth And Physiology Of Shallot (Allium Ascalonicum L.), Etik Wukir Tini, Rifqi Raditya Kurniawan
Jurnal Kultivasi
Rabbit urine liquid organic fertilizer (LOF) can be used as an alternative fertilizer to reduce the use of inorganic fertilizers, especially for shallots, as a national food commodity. This study aims to determine the best concentration of rabbit urine LOF, the best dose of NPK fertilizer dose reduction, and a combination of rabbit urine LOF and NPK fertilizer dose reduction on the physiological characters of shallot plants. The observed variables consisted of net assimilation rate, crop growth rate, stomatal density, stomatal aperture, and chlorophyll content. The experimental results showed that a concentration of 200 mL L-1 of rabbit urine LOF …
The Effect Of Melatonin And 6-Benzylaminopurine Application On The Post-Harvest Quality Of Cut Roses (Rosa X Alba), Azizah Tiara Putri, Syariful Mubarok, Rahmat Budiarto
The Effect Of Melatonin And 6-Benzylaminopurine Application On The Post-Harvest Quality Of Cut Roses (Rosa X Alba), Azizah Tiara Putri, Syariful Mubarok, Rahmat Budiarto
Jurnal Kultivasi
Roses are known as a high-value commodity frequently used in various important events. However, they are susceptible to postharvest quality deterioration, which can affect their vase life and appearance. In this study, roses with a blooming stage of approximately 25–50% were immersed in melatonin and 6-benzylaminopurine (BAP) solutions at different concentrations. This research aims to analyze the effect of melatonin and BAP application on the freshness of cut roses. The parameters observed included flower vase life, flower wilting angle, increase in flower diameter, fresh weight, solution uptake, and chlorophyll content. The results showed that melatonin and BAP, applied individually or …
Approaches For Identifying Lncrna-Associated Proteins For Therapeutic Targets And Cancer Biomarker Discovery, Mohammad Shabir Hussain, Puneet Vij, Sudhir Kotnala, Shadab Ahmad, Subhash Chauhan, Manish Kumar Tripathi
Approaches For Identifying Lncrna-Associated Proteins For Therapeutic Targets And Cancer Biomarker Discovery, Mohammad Shabir Hussain, Puneet Vij, Sudhir Kotnala, Shadab Ahmad, Subhash Chauhan, Manish Kumar Tripathi
School of Medicine Publications
Long non-coding RNAs (lncRNAs) are increasingly recognized as key regulators of gene expression and cellular signaling in cancer. Their functions are primarily mediated through interactions with specific protein partners that modulate chromatin structure, epigenetic remodeling, transcription, and signal transduction. In this review, we explore reports and strategies for the proteomic characterization of lncRNA-associated proteins, particularly emphasizing high-throughput liquid chromatography–mass spectrometry (LC-MS)-based techniques. Affinity-based methods such as RNA pull-down, ChIRP MS, RAP-MS, BioID-MS, and SILAC-MS enable sensitive and specific mapping of lncRNA and protein complexes. These approaches reveal cancer-specific proteomic signatures, post-translational modifications, and mechanistic insights into tumor biology. The use …
Optimising The Care Of The Trapped Patient Following A Motor Vehicle Collision: A Uk-Based Delphi Consensus Study, Tim Nutbeam, Rob Fenwick, Ian Marritt, Brian Lee, Luke Staveley-Wadham, Nigel Lang, Louise Johnson, Nicolas Mattock, Jane Ogilvie, Emily Foote, Francis Screech, Lara Lebeau-Humarau, Caroline Leech
Optimising The Care Of The Trapped Patient Following A Motor Vehicle Collision: A Uk-Based Delphi Consensus Study, Tim Nutbeam, Rob Fenwick, Ian Marritt, Brian Lee, Luke Staveley-Wadham, Nigel Lang, Louise Johnson, Nicolas Mattock, Jane Ogilvie, Emily Foote, Francis Screech, Lara Lebeau-Humarau, Caroline Leech
Peninsula Medical School
Background Motor vehicle collisions (MVCs) are a leading cause of injury and death worldwide. Up to 40% ofcasualties may become trapped and entrapment is associated with delayed care and worse outcomes. There is littlenational or international consensus guiding the care of physically trapped patients who cannot self-extricate. Thisstudy aimed to develop multidisciplinary consensus-based principles to optimise clinical and operational care fortrapped patients following MVC.Methods A three-round Delphi study was conducted from January to March 2025, following the CREDES framework.A multi-professional steering group developed preliminary statements informed by literature review and expertconsultation. Subject matter experts (SMEs) with operational experience in extrication, …
European And African Ancestry-Specific Plasma Protein-Qtl And Metabolite-Qtl Analyses Identify Ancestry-Specific T2d Effector Proteins And Metabolites, Chengran Yang, Priyanka Gorijala, Jigyasha Timsina, Lihua Wang, Menghan Liu, Ciyang Wang, William Brock, Yueyao Wang, Fumihiko Urano, Yun Ju Sung, Carlos Cruchaga
European And African Ancestry-Specific Plasma Protein-Qtl And Metabolite-Qtl Analyses Identify Ancestry-Specific T2d Effector Proteins And Metabolites, Chengran Yang, Priyanka Gorijala, Jigyasha Timsina, Lihua Wang, Menghan Liu, Ciyang Wang, William Brock, Yueyao Wang, Fumihiko Urano, Yun Ju Sung, Carlos Cruchaga
2020-Current year OA Pubs
In this study, we generated and integrated plasma proteomics and metabolomics with the genotype datasets of over 2300 European (EUR) and 400 African (AFR) ancestries to identify ancestry-specific multi-omics quantitative trait loci (QTLs). In total, we mapped 954 AFR pQTLs, 2848 EUR pQTLs, 65 AFR mQTLs, and 490 EUR mQTLs. We further applied these QTLs to ancestry-stratified type-2 diabetes (T2D) risk to pinpoint key proteins and metabolites underlying the disease-associated genetic loci. Using INTACT that combined trait-imputation and colocalization results, we nominated 270 proteins and 72 metabolites from the EUR set; seven proteins and one metabolite from the AFR set …
Degradation Of Anthropogenic Debris In Stormwater Infrastructure Of The Lake Ontario Watershed, Evan Batte
Degradation Of Anthropogenic Debris In Stormwater Infrastructure Of The Lake Ontario Watershed, Evan Batte
Theses
The accumulation of anthropogenic debris (AD) in the Great Lakes is a growing issue with largely unknown consequences for ecological and human health. To better constrain estimates of debris loading into Lake Ontario and elucidate the fate of AD accumulating upstream, an incubation experiment of the most commonly identified littered products was conducted in different stormwater infrastructure within the Lake Ontario Watershed. Chip bags, cigarette filters, and shopping bags were placed into storm drains, stormwater retention ponds, and along riparian zones of tributaries in December of 2022 and July of 2023 to test the spatial (type of stormwater infrastructure [SWI]) …