Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Social and Behavioral Sciences (658192)
- Arts and Humanities (572832)
- Law (543367)
- Education (382262)
- Medicine and Health Sciences (325139)
-
- Physical Sciences and Mathematics (292551)
- Life Sciences (256245)
- Engineering (196034)
- History (181437)
- Business (149002)
- Higher Education (142749)
- Anthropology (115951)
- Religion (109831)
- Archaeological Anthropology (96468)
- Communication (89126)
- Sociology (86470)
- Library and Information Science (80027)
- United States History (77509)
- Medical Specialties (76851)
- Psychology (73599)
- Computer Sciences (63011)
- Public Affairs, Public Policy and Public Administration (62465)
- Earth Sciences (59349)
- Creative Writing (57942)
- Public Health (55609)
- Environmental Sciences (52386)
- English Language and Literature (47507)
- Economics (46828)
- Educational Administration and Supervision (46483)
- Music (45912)
- Institution
-
- University of South Florida (163042)
- University of New Mexico (139283)
- University of Nebraska - Lincoln (114006)
- Kenyon College (112919)
- University of Montana (98384)
-
- University of Mississippi (94607)
- University of New Hampshire (79656)
- Brigham Young University (72176)
- Georgia Southern University (61523)
- Eastern Illinois University (57888)
- Utah State University (57349)
- Mississippi State University (54520)
- Western Michigan University (52952)
- University of Kentucky (52307)
- Murray State University (50490)
- Purdue University (50072)
- University of Colorado Law School (47452)
- Louisiana State University (45136)
- Brigham Young University Law School (43713)
- University of Dayton (43232)
- Western Kentucky University (43085)
- Villanova University Charles Widger School of Law (42715)
- California Polytechnic State University, San Luis Obispo (42492)
- University of Central Florida (41628)
- Chulalongkorn University (37375)
- San Jose State University (36971)
- University of Northern Iowa (35969)
- University of Alabama at Birmingham (35953)
- Yale University (33842)
- Missouri University of Science and Technology (33676)
- Keyword
-
- Newspaper (47505)
- Latin America (31532)
- Press release; media release; press statement; news media information (30839)
- Spanish (30833)
- History (30081)
-
- University of New Mexico (29735)
- UNM (29638)
- LADB (29608)
- LAII (29608)
- Latin American and Iberian Institute (29608)
- Humans (29451)
- Education (28969)
- United States (21359)
- Student newspaper (19995)
- Newsletter (19706)
- EIU (19627)
- Georgia Southern University (18903)
- Newspapers (18264)
- Deaf culture (17102)
- Hearing impaired (17091)
- Pastoral care of people with disabilities (17060)
- Church work with the deaf -- Catholic Church (17052)
- Deaf -- Periodicals (17043)
- Athletics (16850)
- Marriage (16179)
- Poetry (15533)
- Students (15120)
- Higher education (14580)
- COVID-19 (14396)
- Female (14245)
- Publication Year
-
- 2026 (102898)
- 2025 (156404)
- 2024 (192659)
- 2023 (162874)
- 2022 (167798)
-
- 2021 (195845)
- 2020 (169204)
- 2019 (165291)
- 2018 (169976)
- 2017 (160796)
- 2016 (159439)
- 2015 (146245)
- 2014 (135655)
- 2013 (129978)
- 2012 (124621)
- 2011 (108186)
- 2010 (103554)
- 2009 (95661)
- 2008 (92734)
- 2007 (79194)
- 2006 (74519)
- 2005 (70126)
- 2004 (71233)
- 2003 (58623)
- 2002 (64473)
- 2001 (55053)
- 2000 (58456)
- 1996 (62300)
- 1992 (52975)
- 1990 (53642)
- Publication
-
- Four Valleys Archive (90475)
- Theses and Dissertations (74027)
- Faculty Publications (45665)
- Electronic Theses and Dissertations (35897)
- University of Montana News Releases, 1928, 1956-present (30910)
-
- Faculty Scholarship (25304)
- Dissertations (23678)
- The Auk (22791)
- Documents (21831)
- Theses (21690)
- Articles (20016)
- Browse All News (19555)
- Walden Dissertations and Doctoral Studies (19539)
- Masters Theses (18625)
- Master's Theses (18423)
- Chulalongkorn University Theses and Dissertations (Chula ETD) (15281)
- Session Laws 1951-2000 (15051)
- NotiSur (13785)
- Faculty, Staff and Student Publications (13696)
- Hillsborough County Marriage Records (13681)
- University of Mississippi News (13497)
- Obituaries (13320)
- The Murray Ledger & Times (13003)
- Sheet Music Collection (12976)
- Michigan Law Review (12806)
- University of Montana Course Syllabi (12469)
- Honors Theses (12169)
- Graduate Theses, Dissertations, and Problem Reports (ETD) (11863)
- Condor (11821)
- Defensive Publications Series (11753)
- Publication Type
Articles 143191 - 143220 of 5153792
Full-Text Articles in Entire DC Network
Graduate School Blog - September 2025 Volume 2, Cynthia Haynes, Cynthia Haynes
Graduate School Blog - September 2025 Volume 2, Cynthia Haynes, Cynthia Haynes
UofM Grad School Blog
In this September Blog volume 2, The University of Memphis graduate certificates provide a flexible, efficient, and affordable pathway for career growth, allowing students to gain specialized skills in as little as 18 months without committing to a full degree. With over 70 programs many offered online or in the evenings students can bridge the gap between knowledge and practice in fields such as Clinical Social Work, Play Therapy, Museum Studies, and Population Health. These four-course programs deliver immediate workplace value while keeping the option open for further graduate study. Highlighted by student experiences like Andrew Hashimura’s in College and …
Strong External Difference Families And Classification Of Α-Valuations, Donald L. Kreher, Maura B. Paterson, Douglas R. Stinson
Strong External Difference Families And Classification Of Α-Valuations, Donald L. Kreher, Maura B. Paterson, Douglas R. Stinson
Michigan Tech Publications
One method of constructing (Formula presented.) -SEDFs (i.e., strong external difference families) in (Formula presented.) makes use of (Formula presented.) -valuations of complete bipartite graphs (Formula presented.). We explore this approach and we provide a classification theorem which shows that all such (Formula presented.) -valuations can be constructed recursively via a sequence of “blow-up” operations. We also enumerate all (Formula presented.) -SEDFs in (Formula presented.) for (Formula presented.) and we show that all these SEDFs are equivalent to (Formula presented.) -valuations via affine transformations. Whether this holds for all (Formula presented.) as well is an interesting open problem. We also …
Review Of Jerusalem And Other Holy Places As Foci Of Multireligious And Ideological Confrontation, Rivka Ulmer
Review Of Jerusalem And Other Holy Places As Foci Of Multireligious And Ideological Confrontation, Rivka Ulmer
Other Faculty Research and Publications
No abstract provided.
Medication Adherence: A Reimbursable Theory-Guided Evidence-Based Educational Intervention For Patients With Parkinson’S Disease, Amanda E. George, Melinda Hermanns, Diane B. Monsivais, Cheryl D. Parker
Medication Adherence: A Reimbursable Theory-Guided Evidence-Based Educational Intervention For Patients With Parkinson’S Disease, Amanda E. George, Melinda Hermanns, Diane B. Monsivais, Cheryl D. Parker
Nursing Faculty Publications and Presentations
Background: Parkinson’s disease is a challenging, progressive neurodegenerative process projected to affect more than 1.2 million patients by 2030, with an economic burden that will surpass $79 billion annually in the United States. Pharmacological interventions are the hallmark of treatment for symptom management for this lifelong disease. Multiple medications and a variety of dosing times have an increasingly negative effect on medication adherence. Purpose: This article will discuss medication adherence challenges, describe a theory-guided evidence-based intervention to improve medication adherence, and explore the economic implications in an outpatient clinic setting. Methods: A pilot chart review of 40 cases over 30 …
The Library Papers (Vol. 1, Issue 1, September 2025), Wolf Law Library, William & Mary Law School
The Library Papers (Vol. 1, Issue 1, September 2025), Wolf Law Library, William & Mary Law School
Library Newsletter
No abstract provided.
Transient Effects Of Antenna Geometry On Direct Antenna Modulation Systems, Tyson Decastro
Transient Effects Of Antenna Geometry On Direct Antenna Modulation Systems, Tyson Decastro
Electrical and Computer Engineering Master's Theses
Electrically small antennas (ESAs) operate with low radiation efficiency and high Q-factor, requiring greater power consumption and slower data rates in wireless communication systems. Direct Antenna Modulation (DAM) refers to a class of modulation techniques, often utilizing a time-varying switch, which significantly reduces the symbol transition time in wireless communication systems with ESAs. Despite the ability to avoid the band-limited nature of ESAs, the increased data rates associated with DAM come at the expense of undesired radiation transients and power radiated in sidebands, which can be disruptive to other communication channels. These effects vary greatly with antenna geometry. In this …
Risk, Uncertainty, World Business Cycles, And The U.S. Stock-Oil Relationship, André Varella Mollick
Risk, Uncertainty, World Business Cycles, And The U.S. Stock-Oil Relationship, André Varella Mollick
Economics and Finance Faculty Publications
We examine in this paper the transmission of geopolitical risks (GPR), VIX, economic policy uncertainty (EPU), and “macro uncertainty” shocks to real WTI oil and U.S. stock returns (S&P 500). Structural vector autoregressions (SVAR) are applied to monthly data from 1990:1 to 2023:6 with identification based on long-run restrictions of impulse responses from risk/uncertainty measures to world industrial production. The main results are: First, oil prices respond positively to shocks in GPR and macro uncertainty in the short-run, but not to shocks in VIX and EPU. Second, stock returns respond negatively and for longer to both GPR and VIX shocks. …
Labor’S Revival: Unions And The Struggle For Racial And Economic Justice -- Event Poster, Lender Center For Social Justice
Labor’S Revival: Unions And The Struggle For Racial And Economic Justice -- Event Poster, Lender Center For Social Justice
The Lender Center for Social Justice
A poster for the Labor's Revival event.
Closing The Racial Wealth Gap: Public, Private, And Philanthropic Collaborations -- Event Program, Lender Center For Social Justice
Closing The Racial Wealth Gap: Public, Private, And Philanthropic Collaborations -- Event Program, Lender Center For Social Justice
The Lender Center for Social Justice
A four page program for the “Closing the Racial Wealth Gap: Public, Private and Philanthropic Collaborations” conference.
Interrogating The Racial Wealth Gap: Thinking Locally -- Event Program, Lender Center For Social Justice
Interrogating The Racial Wealth Gap: Thinking Locally -- Event Program, Lender Center For Social Justice
The Lender Center for Social Justice
A pamphlet for the Interrogating the Racial Wealth Gap: Thinking Locally event.
Halle Library: Library Copyright Policy And Guidelines
Halle Library: Library Copyright Policy And Guidelines
Academic Affairs – Policy Library
No abstract provided.
Art 399 Portfolio, Bailey D. Provine
Art 399 Portfolio, Bailey D. Provine
Professional Practices (ART 399)
The United States foundation is built on laborers and the importance of sacrifice. My Dad and my Grandaddy provided for our family by working construction and building custom cars for many years. Their hard work provides a prosperous and fulfilling life, but it takes a toll on their bodies. My work explores the softer side of manual labor. Through watching and working beside them, I have learned the value of hard work. Through depictions of trade work in my paintings, I connect to the shared experience of living in the rural United States and cultivate an appreciation for these labors …
Penicillin Adverse Drug Reaction (Historical), Children's Mercy Kansas City
Penicillin Adverse Drug Reaction (Historical), Children's Mercy Kansas City
Clinical Pathways
No abstract provided.
Fever In The Returned Traveler, Children's Mercy Kansas City
Fever In The Returned Traveler, Children's Mercy Kansas City
Clinical Pathways
No abstract provided.
Repair/Preservation Of Concrete Compression Members In Bridges Using Ultra-High-Performance Concrete (Uhpc), Mohammed Hedia, George Morcous
Repair/Preservation Of Concrete Compression Members In Bridges Using Ultra-High-Performance Concrete (Uhpc), Mohammed Hedia, George Morcous
Nebraska Department of Transportation: Research Reports
As of 2024, approximately 36% of bridges across the United States require repair or replacement, with 7% classified as structurally deficient. The estimated cost to address these deficiencies exceeds $260 billion. In recent years, Ultra-High-Performance Concrete (UHPC) has emerged as a repair material for infrastructure preservation, drawing increased attention from transportation agencies and researchers worldwide. The Federal Highway Administration (FHWA) has notably advocated for UHPC’s adoption in bridge preservation initiatives, recognizing its exceptional mechanical properties and durability.
This report presents a comprehensive literature review on the application of UHPC as a repair and strengthening material for bridge compression members. While …
The Uk's Intended Move To Electric And Connected And Autonomous Vehicles: Are Infrastructural Barriers Preventing Successful Transition?, Katy Ferris, James Marson
The Uk's Intended Move To Electric And Connected And Autonomous Vehicles: Are Infrastructural Barriers Preventing Successful Transition?, Katy Ferris, James Marson
Transportation Law Journal
The advent of Connected and Autonomous Vehicles (CAVs) is poised to transform global transportation systems, offering unparalleled opportunities to enhance safety, sustainability, and efficiency. Given that CAVs are most likely also to be electric vehicles (EVs), and in the UK, CAVs/EVs are a central element of government efforts to modernise mobility while achieving net-zero emissions by 2050, it would seem the UK is ready to embrace the transition to this new and disruptive form of transportation. However, while technological innovation has surged, critical questions remain about the readiness of physical, digital, and policy infrastructures to support the widespread adoption of …
From Displacement To Design: Reframing Work, Skills, And Education For The Ai-Transformed Economy A Review, James Hutson
From Displacement To Design: Reframing Work, Skills, And Education For The Ai-Transformed Economy A Review, James Hutson
Faculty Scholarship
Between 2023 and 2025, the U.S. labor market entered a period of accelerated restructuring driven by generative artificial intelligence (AI) and automation. Routine, entry-level cognitive roles—particularly in clerical, customer service, and junior technical positions—contracted sharply as intelligent systems assumed high-volume, rules-based tasks. While these displacements echo past automation cycles, the present transformation is distinct in its scope, affecting both knowledge work and creative functions, and in its speed, amplified by enterprise-scale adoption. Simultaneously, demand has surged for specialized AI-related positions, interdisciplinary roles blending domain expertise with AI fluency, and ―durable skills‖ that remain resistant to automation. Drawing on labor market …
Dual Investigations Into Broiler Health: Mitochondrial Gene Expression In Ascites Susceptibility And G-1,25(Oh)₂D₃-Driven Modulation Of Bone And Gut Integrity In Lameness, Layla Hussein Al-Mitib
Dual Investigations Into Broiler Health: Mitochondrial Gene Expression In Ascites Susceptibility And G-1,25(Oh)₂D₃-Driven Modulation Of Bone And Gut Integrity In Lameness, Layla Hussein Al-Mitib
Graduate Theses and Dissertations
Modern broiler production faces persistent challenges from metabolic and skeletal disorders, particularly ascites and bacterial chondronecrosis with osteomyelitis (BCO), which compromise animal welfare and production efficiency. This dissertation examines two key factors that contribute to these conditions: mitochondrial gene expression associated with pulmonary hypertension syndrome (PHS) and the role of intestinal barrier integrity in mitigating lameness. In the first study, the expression of mitochondrial genes COXII and ATP6 was evaluated in the breast, thigh, and lung tissues of three broiler genetic lines—ascites-susceptible (SUS), ascites-resistant (RES), and unselected relaxed (REL). While no significant expression differences were observed in muscle tissues, SUS …
Moral Worth And Motivational Demands, Spencer Heitman
Moral Worth And Motivational Demands, Spencer Heitman
Graduate Theses and Dissertations
It has become a philosophical commonplace to distinguish actions that are merely right from actions that possess moral worth. To be right, an action needs only to accord with the demands of morality. To possess moral worth, an action needs not only to be right, but to be non-accidentally so. While this much is uncontroversial, what is involved in this sense of non-accidentality is a matter of ongoing debate. This thesis lies at the heart of that debate. Many parties to this debate agree that actions with moral worth must be properly motivated. Suppose someone speaks respectfully to a colleague …
Ab Initio Studies On Mechanical Properties Of Freestanding Ferroic Monolayers, John Malcolm Davis
Ab Initio Studies On Mechanical Properties Of Freestanding Ferroic Monolayers, John Malcolm Davis
Graduate Theses and Dissertations
This thesis explores the role of mechanical properties and elastic couplings in freestanding paradigmatic ferroic monolayers within the framework of density functional theory. This dissertation is comprised of three interconnected published studies: (i) establishing the elastic behavior across a temperature-driven phase transition in SnSe monolayers; (ii) thermally-driven phase transitions in graphene-like silicene, germanene, and stanene, examining the structural stability and band gap occlusion; and (iii) magnetoelastic coupling in an Ising-like CrSiTe3 monolayer, focused on assessing magnetic contributions to the material stiffness by establishing a proper non-magnetic reference.
A Dynamic Hierarchical Attention Framework For Multimodal Malware Detection, Tamanna Nazmin
A Dynamic Hierarchical Attention Framework For Multimodal Malware Detection, Tamanna Nazmin
Graduate Theses and Dissertations
The increasing use of Android in the worldwide mobile ecosystem has come along with a significant increase in advanced malware, highlighting the critical necessity for efficient, scalable, and adaptable detection systems. Despite recent advancements in machine learning improving malware detection, the majority of current solutions are limited to one, two, or three data modalities, hence neglecting the comprehensive behavioral spectrum of contemporary multi-vector threats. This thesis presents the first comprehensive multimodal framework for Android malware detection, which combines textual, time-series (temporal), graph-based (structural), and visual information using an innovative hierarchical attention mechanism and Dynamic Fusion Controller(DFC). Our methodology consistently classifies …
University Of Nebraska At Omaha Enrollment Profile Report: Fall 2025, Systems Intelligence And Data Analytics, University Of Nebraska At Omaha
University Of Nebraska At Omaha Enrollment Profile Report: Fall 2025, Systems Intelligence And Data Analytics, University Of Nebraska At Omaha
Enrollment Reports
headcount and student credit hours, as well as the demographic characteristics of enrolled students. Delivery-site reporting counts all students, including those in UNL programs delivered at UNO, but excludes UNO programs delivered in Lincoln (CPACS programs). Administrative-site reporting counts students enrolled in UNO programs only (including the CPACS programs delivered in Lincoln). The purpose of this profile is to provide the undergraduate and graduate enrollments and student credit hour information by college or equivalent academic unit, class, gender and ethnicity. A glossary at the end of the report provides a list of definitions for headings. All information in this report …
Adversaguard: A Distributed Data-Poisoning Benchmark For Parallel Ai, Yulia Kumar, Solomon Thomas, Dejaun Gayle, J. Jenny Li, Dov Kruger
Adversaguard: A Distributed Data-Poisoning Benchmark For Parallel Ai, Yulia Kumar, Solomon Thomas, Dejaun Gayle, J. Jenny Li, Dov Kruger
Center for Cybersecurity
As organizations scale model training across large clusters and clouds, data poisoning has emerged as a significant practical threat. Most existing research focuses on data poisoning in single-node environments. Far fewer studies have compared the effectiveness of attacks across parallel training strategies, where factors like gradient aggregation and distributed memory ceilings fundamentally alter attack detectability and its impacts. To address this gap, we introduce AdversaGuard, a reproducible benchmark and accompanying application designed specifically for distributed settings to protect AI training pipelines. This research makes the following key contributions: (1) A comprehensive Distributed Data Poisoning (DDP) benchmark spanning seven distributed systems …
Enhancing Non-Player Character Dialogue In Video Gages: An Evaluation Of Large Language Model-Generated Responses, Lam P. Quach
Enhancing Non-Player Character Dialogue In Video Gages: An Evaluation Of Large Language Model-Generated Responses, Lam P. Quach
Master's Theses
As video games increasingly emphasize narrative depth and player immersion, the quality of Non-Player Character (NPC) dialogue has become crucial for creating engaging gaming experiences. This thesis investigates the potential of Large Language Models (LLMs) to generate high-quality NPC dialogue by comprehensively evaluating four state-of-the-art models: Gemma 3 27B, Mistral 7B, QWEN 2.5, and LLAMA 3.1. The study employs a mixed-methods approach, combining human evaluation (N=50 participants) with AI-based assessment across five key benchmarks: coherence, personality expression, engagement, style/tone appropriateness, and overall quality. Participants evaluated 32 dialogue samples (8 per model) generated for a fantasy game context featuring two distinct …
Introduction To Us Government & Politics Syllabus, Jennifer Corby
Introduction To Us Government & Politics Syllabus, Jennifer Corby
Open Educational Resources
This syllabus outlines the structure and pedagogical design of POL 51: Introduction to U.S. Government and Politics, taught at Kingsborough Community College (CUNY). Developed as part of an Open Educational Resources (OER) course redesign funded through the CUNY OER Initiative, the course integrates accessible, cost-free materials from Attenuated Democracy: A Critical Introduction to U.S. Government and Politics alongside multimodal, student-centered learning activities. The course emphasizes Universal Design for Learning (UDL), ungrading, and reflective journaling to foster civic engagement and metacognitive awareness. A central innovation of this version is a two-week Critical AI Literacy (CALI) module that situates artificial intelligence …
First-Time Mothers' Experiences Of Breastfeeding During The Early Postpartum Period In Nairobi, Kenya: A Qualitative Study, Viola Siongei, Rose Maina, Eunice Pallangyo
First-Time Mothers' Experiences Of Breastfeeding During The Early Postpartum Period In Nairobi, Kenya: A Qualitative Study, Viola Siongei, Rose Maina, Eunice Pallangyo
School of Nursing & Midwifery, East Africa
Background/Aims The rate of exclusive breastfeeding in the first 6 months is still low, despite global active promotion of the practice. The exclusive breastfeeding rate among first-time mothers is much lower than among multiparous women, which has been attributed to difficulties assuming the new role and a lack of breastfeeding skills. This study aimed to gain an in-depth understanding of first-time mothers' breastfeeding experiences and the factors that influence these experiences during the early postpartum period in Nairobi, Kenya.
Methods This qualitative explorative, descriptive study involved 17 purposively sampled first-time mothers at 4–6 weeks postpartum. In-depth, face-to-face semi-structured interviews were …
Association Between Decisional Conflict And Quality Of Life Among Parents With A Child Undergoing Hospital-Based Treatment For A Recent Cancer Diagnosis, Augustine Provencio
Association Between Decisional Conflict And Quality Of Life Among Parents With A Child Undergoing Hospital-Based Treatment For A Recent Cancer Diagnosis, Augustine Provencio
Doctoral Dissertations
Having a child with a chronic illness, such as cancer, can cause families significant distress. Parents of these children must make frequent decisions relating to their child’s care. Depending on factors such as health literacy and support from medical staff, parents may have varying levels of decisional conflict (DC) throughout the decision-making process. Compounding stress throughout their child’s illness can often contribute to lower levels of health-related quality of life (HRQoL) while their child is receiving hospital-based treatment. Parents with a non-English language preference (NELP) often have greater challenges navigating healthcare systems due to a lack of resources and limited …
Experiences And Perspectives Of Sexual And Reproductive Health Among Women In Recovery From Opioid Use Disorder, Nicole M. Mattson, Aleigha Barry, Jessica L. Zemlak
Experiences And Perspectives Of Sexual And Reproductive Health Among Women In Recovery From Opioid Use Disorder, Nicole M. Mattson, Aleigha Barry, Jessica L. Zemlak
College of Nursing Faculty Research and Publications
Background
Women in recovery from opioid use disorder (OUD) have unmet sexual and reproductive health (SRH) needs resulting in health disparities such as unintended pregnancy and sexually transmitted infections/HIV infection compared with women without OUD. The purpose of this qualitative descriptive study was to explore the perceptions and experiences of co-occurring multiple social-ecologic influences (individual, interpersonal, community, society) on SRH among women in recovery from OUD.
Methods
Purposive sampling was used to recruit cis-gender women aged 18–49 who self-identify as being in recovery from OUD and speak English. We conducted one 45- to 60-minute audio-recorded semistructured telephone interview with each …
Adaptive Filters At The First Olfactory Synapse, Elizabeth H Moss, Benjamin R Arenkiel
Adaptive Filters At The First Olfactory Synapse, Elizabeth H Moss, Benjamin R Arenkiel
Duncan NRI Faculty and Staff Publications
The olfactory system is able to filter odor representations based on attention and learning. Two PLoS Biology studies reveal how short axon cells in the olfactory bulb integrate cholinergic input from the basal forebrain to dynamically regulate olfactory input.
Diagnostic Yield Of Exome Sequencing For Pregnancies With And Without Fetal Anomalies And For Stillbirth, Roni Zemet, Christian M Parobek, April D Adams, Mohamad Ali Maktabi, Lena Shay, Linyan Meng, Pengfei Liu, Hongzheng Dai, Fan Xia, Christine Eng, Ignatia B Van Den Veyver, Liesbeth Vossaert
Diagnostic Yield Of Exome Sequencing For Pregnancies With And Without Fetal Anomalies And For Stillbirth, Roni Zemet, Christian M Parobek, April D Adams, Mohamad Ali Maktabi, Lena Shay, Linyan Meng, Pengfei Liu, Hongzheng Dai, Fan Xia, Christine Eng, Ignatia B Van Den Veyver, Liesbeth Vossaert
Duncan NRI Faculty and Staff Publications
Objective: Exome sequencing (ES) benefits the genetic work-up for fetuses with structural anomalies, but data on its utility for fetuses without anomalies and stillbirths is more limited. We report our experience with prenatal ES for all three indications.
Method: We retrospectively reviewed results from 344 trio-ES performed for fetuses with structural anomalies (N = 262), stillbirths (N = 39), and fetuses without anomalies (N = 43), many of which had a relevant family history. We classified pathogenic variants (P), likely pathogenic variants (LP), or variants of uncertain significance (VUS) favoring pathogenicity in a gene consistent with the fetal phenotype as …