Digital Commons Network^™

Advanced Deep Neural Network Architectures For 3d Gait Assessment From Video In The Early Detection Of Alzheimers Disease, Abhishek Singh Kushwaha

Electronic Theses and Dissertations 2020 - Present

This thesis presents an advanced deep learning framework for markerless 3D gait assessment using monocular video, aimed at the early detection of Alzheimer’s disease (AD). Recognizing gait abnormalities as potential preclinical biomarkers, the study leverages video-based human pose estimation to derive detailed spatiotemporal gait parameters without the need for specialized laboratory equipment. The proposed system adapts the MeTRAbs (Metric-Scale Truncation-Robust Heatmaps for Absolute 3D Human Pose Estimation) architecture to reconstruct metric-scale 3D human joint coordinates from RGB video recordings. A complete processing pipeline is developed to extract stride length, cadence, stance and swing phases, and gait variability, validated against the …

Being An Art Lawyer, Cardozo Fame Center, Cardozo Art Law Society

2025–2026 Flyers

No abstract provided.

Mycobacterium Chelonae Outbreak Investigation At A Quaternary Pediatric Hospital Following The Opening Of A Leed-Certified Critical Care Tower: Where Does Water Sustainability Intersect With Infection Control?, Andrea L Ankrum, Silvia M Caceres, Michael Torsell, Elaine Epperson, Vinicius Calado Nogueira De Moura, Michael Strong, Matthew J Strand, Rachel N Wilsey, Jennifer R Honda, Jane E Gross, Felicia A Scaggs-Huang

Faculty, Staff and Student Publications

Objective: Investigate the increased incidence of Mycobacterium chelonae positive respiratory cultures in hospitalized patients.

Design: Apply the Healthcare-Associated Links in Transmission of Nontuberculous Mycobacteria (HALT NTM) toolkit to an outbreak investigation of M. chelonae.

Setting: Quaternary-care pediatric hospital and medical center in the United States with a recently opened LEED-certified critical care tower.

Patients: Adult and pediatric patients with M. chelonae positive respiratory cultures between June 2022 and January 2024.

Methods: An epidemiological investigation involving clinical and laboratory practices, water management, building construction and renovation projects. Environmental sampling of air vents, water sources and endoscope reprocessing equipment was performed. M. …

Stiefel Md Anderson Oropharynx Cancer (Mda-Opc) Cohort: A Single-Institution, Prospective Longitudinal Outcomes Study, Amy Moreno, Ariana J Sahli, Faye Johnson, Xiaowen Sun, Carly Barbon, Wenye Song, Han Liang, Jun Li, Wei Liu, J Jack Lee, S J Frank, Stephen Lai, Clifton Fuller, Katherine Hutcheson

Faculty, Staff and Student Publications

Purpose: The MD Anderson Oropharynx Cancer (MDA-OPC) cohort is a unique single-institution, prospective longitudinal cancer cohort. The cohort aims to enhance the therapeutic index of OPC management by supporting data needs for independent investigators to conduct rigorous observational studies examining exposures and factors associated with acute and late toxicities, cancer progression, recurrence, new malignancies and quality of life in OPC survivors.

Participants: A total of 1811 patients with OPC with a minimum follow-up of 6 months have been consented to our prospective registry between 18 March 2015 and 29 December 2023. Clinical and treatment (Tx) data are available on all …

Live-Cell Quantitative Monitoring Reveals Distinct, High-Affinity Gβγ Regulations Of Girk2 And Girk1/2 Channels, Reem Handklo-Jamal, Tal Keren Raifman, Boris Shalomov, Patrick Hofer, Uri Kahanovitch, Galit Tabak, Haritha P Reddy, Orna Chomsky-Hecht, Debi Ranjan Tripathy, Kerstin Zuhlke, Carmen W Dessauer, Enno Klussmann, Yoni Haitin, Joel A Hirsch, Anna Stary-Weinzinger, Daniel Yakubovich, Nathan Dascal

Faculty, Staff and Student Publications

Gi/o protein-coupled receptors (GPCRs) inhibit cardiac and neuronal excitability via G protein-activated K+ channels (GIRK), assembled by combinations of GIRK1 - GIRK4 subunits. GIRKs are activated by direct binding of the Gβγ dimer of inhibitory Gi/o proteins. However, key aspects of this textbook signaling pathway remain debated. Recent studies suggested no Gi/o-GIRK pre-coupling and low (>250 µM) Gβγ-GIRK interaction affinity, contradicting earlier sub-µM estimates and implying low signaling efficiency. We show that Gγ prenylation, which mediates Gβγ membrane attachment required for GIRK activation, also contributes to the Gβγ-GIRK interaction, explaining the poor affinity obtained with non-prenylated Gβγ. Using quantitative …

Analysis Of A Deeply-Phenotyped Familial Hypercholesterolemia Cohort From Mexico Shows A Role For Both Rare And Common Alleles Across Known Dyslipidemia Genes And Reveals Structural Variation In A Novel Locus, Nicholas Katsanis, Niki Mourtzi, Consuelo D Quinto-Cortés, Alexandro J Martagon, Alexander G Ioannidis, Jeff Gulcher, Mohammad A Faghihi, Arturo Lopez-Pineda, Sonia Moreno-Grau, Daniel Mas Montserrat, Míriam Barrabés, David Bonet, Pavel Salazar Fernandez, Jeff Wall, Babak Moatamed, Roopa Mehta, Gabriela A Galan-Ramirez, Rafael Zubirán, Daniel Elias-Lopez, Teresa Tusié-Luna, Carlos A Aguilar-Salinas, Carlos D Bustamante

Faculty, Staff and Student Publications

Familial hypercholesterolemia (FH) is a genetic disorder driven in part by mutations in three genes that encode components of the cholesterol pathway: LDLR, APOB, and PCSK9. However, the majority of FH genetics has been performed in individuals of European descent. Here, we leveraged a cohort of 300 patients from the Mexican FH registry to understand how rare, high liability alleles and common variants might contribute to shaping individual risk. Using a combination of whole exome and of short- and long-read whole genome sequencing, we report three key findings. First, we observed that rare pathogenic point mutations and structural variants in …

Naphthalimide-Based Type-I Nano-Photosensitizers For Enhanced Antitumor Photodynamic Therapy: H2s Synergistically Regulates Pet And Self-Assembly, Huiyu Niu, Songnan Wang, Yang Liu, Nana Ma, Shuaiwei Cheng, Hyunsun Jeong, Ge Wang, Tony D James, Juyoung Yoon, Jonathan L Sessler, Hua Zhang

Faculty, Staff and Student Publications

Photodynamic therapy (PDT) relies on a combination of light and photosensitizers (PSs) to achieve local control over cancerous lesions. However, it is subject to limitations, including tumor hypoxia, low tumor targeting, off‐target phototoxicity, and always‐on fluorescence. Here, we propose a design strategy for activated nano‐PSs (N‐PSs) to simultaneously overcome the limitations of PDT, wherein photoinduced electron transfer (PeT) is coupled with an endogenous H2S‐regulated self‐association process to promote Type‐I photochemical reactions. Using theoretical calculations, spectral analysis, and microscopic imaging, we verified the generation of self‐assembly and occurrence of PeT. And it was also shown that H2S could synergistically inhibit the …

A Geological Carbon Cycle Sink Hosted By Ocean Crust Talus Breccias, Rosalind M. Coggon, Elliot J. Carter, Lewis Grant, Aled D. Evans, Christopher Lowery, Damon A.H. Teagle, Pamela Kempton, Matthew J. Cooper, Claire Routledge, Elmar Albers, Justin Estep, Gail Christeson, Michelle Harris, Thomas Belgrano, Jason Sylvan, Julia Reece, Emily Estes, Trevor Williams

School of Geography, Earth and Environmental Sciences

Calcium carbonate precipitation in ageing ocean crust sequesters carbon dioxide dissolved in seawater through seafloor weathering reactions, influencing atmospheric CO2 concentrations on million-year timescales. However, this crustal carbon sink, and the extent it balances CO2 degassing during crustal formation at mid-ocean ridges, remain poorly quantified due to limited sampling of the vast ridge flanks where CO2 uptake continues for millions of years. Here we quantify the carbon sink hosted within talus breccias that accumulated through mass wasting 61 million years ago during rift faulting at the slow spreading Mid-Atlantic Ridge, cored during International Ocean Discovery Program South Atlantic Transect Expedition …

Thinning Antarctic Glaciers Expose High-Altitude Nunataks Delivering More Bioavailable Iron To The Southern Ocean, Kate Winter, John Woodward, Stuart A. Dunning, James R. Jordan, Joseph A. Graly, Matthew J. Westoby, Sian F. Henley, Robert Raiswell

School of Geography, Earth and Environmental Sciences

Glacial systems entrain and transfer sediment, rich in essential nutrients, from continental sources to the ocean, where they are released by meltwater. In the Southern Ocean, primary producers are limited by the availability of micronutrients, like iron (Fe), so any increase in continental sediment supply could enhance primary productivity and subsequent drawdown of atmospheric CO₂. Here we provide a systematic account of labile Fe concentrations in Antarctic continental sediments. Ferrihydrite and crystalline Fe (oxyhydr)oxides were extracted from 27 Antarctic samples collected from nunataks, lateral moraines and blue ice areas in the Sør Rondane Mountains, East Antarctica. We report …

Innovation Curse: The Wastefulness Of Technologies Believed To Mitigate Climate Change, Minh Hoang Nguyen, Valoree Gagnon, Thanh Tu Tran, Thi Mai Anh Tran

Michigan Tech Publications

Technological innovations are increasingly promoted as solutions to climate change. However, many innovations, including Carbon Capture and Storage, bioplastics, and glacier geo-engineering, suffer significant limitations from high costs, speculative efficacy, and adverse ecological consequences. Using Granular Interaction Thinking Theory (GITT), a transdisciplinary framework grounded in information theory, quantum mechanics, and mindsponge theory, in this study, we explain how such technological innovations become systemically favored despite their flaws. We introduce the concept of the “innovation curse,” which arises when institutional and cognitive filtering systems, operating under high informational entropy, default to familiar but ineffective techno-solutions while marginalizing Indigenous and Local Knowledges …

The Global Hypophosphatasia Registry: Lessons Learned From A Decade Of Real-World Data., Priya S. Kishnani, Lothar Seefried, Keiichi Ozono, Gabriel Ángel Martos-Moreno, Cheryl Rockman-Greenberg, Deborah Fowler, Luke K. Burke, William R. Mowrey, Eric T. Rush, Peter R. Ebeling, Wolfgang Högler, Agnès Linglart, Shona Fang, Anna Petryk, Kathryn M. Dahir

Manuscripts, Articles, Book Chapters and Other Papers

INTRODUCTION: Hypophosphatasia (HPP) is an inherited, metabolic, rare disease characterized by a high level of clinical heterogeneity. In response to this robust heterogeneity, the Global HPP Registry was formed to characterize the types of manifestations that patients may experience, as well as to compile information on genetic underpinnings of the disease, overall impact on patient quality of life, and safety and effectiveness of enzyme replacement therapy. The objective of this review was to synthesize key learnings gained from the Global HPP Registry, which is now in its tenth year of enrolling patients.

METHODS: Registry data were analyzed to provide up-to-date …

For Pete's Sake: A Comparative Analysis On Quantum Review After Pete V. Boland, Joseph X. Kehrli

Louisiana Law Review

No abstract provided.

Fee Multipliers In Class Actions, Andrew J. Trask

Louisiana Law Review

No abstract provided.

Ascertaining Ascertainability, Patrick D. Murphree

Louisiana Law Review

No abstract provided.

Tesla's Forced Middleman: Why Modernization In The Automobile Industry Requires Louisiana To Revise Its Direct Sales Law, John Brainard

Louisiana Law Review

No abstract provided.

Vested Property Rights: Examining The Louisiana Supreme Court's Approach To Substantive Due Process In Bienvenu V. Defendant 1, William Voitier

Louisiana Law Review

No abstract provided.

Masthead

Louisiana Law Review

No abstract provided.

Faculty

Louisiana Law Review

No abstract provided.

Cover

Louisiana Law Review

No abstract provided.

When Laws Leave You Hanging: Negotiorum Gestio Steps In For Self V. Bpx Operating Company, Melisse Speligene

Louisiana Law Review

No abstract provided.

Table Of Contents

Louisiana Law Review

No abstract provided.

Psychopharmacologic Management Of Serious Mental Illness In State Prisons, Clarel Neuvieme

Walden Dissertations and Doctoral Studies

This Doctor of Nursing Practice (DNP) project focused on developing and evaluating an evidence-based clinical practice guideline (CPG) for the psychopharmacologic management of serious mental illness (SMI) in a state correctional health system. The project explored a critical practice gap: the unavailability of standardized, evidence-based prescribing and monitoring protocols for incarcerated individuals diagnosed with schizophrenia, major depressive disorder with psychotic features, or bipolar disorder. The evidence-based project was structured around the central question: “Will an interprofessional team achieve consensus on updating the clinical practice guideline for psychopharmacologic management of serious mental illness in state prisons, thereby improving consistency and quality …

Population Dynamics, Host Range, And Impact Of The Naturalized Weevil Ochyromera Ligustri: A Potential Biological Control Agent Of Invasive Ligustrum Sinense, Brandi H. Misiaszek

LSU Master's Theses

Invasive woody plants have become dominant components of many forest understories in the southeastern United States. These species can displace native species, disrupt ecosystem processes, and reduce biodiversity. Chinese privet (Oleaceae: Ligustrum sinense Lour.) is an invasive shrub distributed through the Southeastern United States. The ligustrum weevil (Coleoptera: Curculionidae: Ochyromera ligustri Warner) is a non-native insect that was first found in the U.S. on Ligustrum in 1959. This weevil is considered a potential fortuitous biological control agent of invasive Ligustrum spp. in the U.S. The objectives of this study were to evaluate O. ligustri as a potential biological control agent …

Flow Control Tactics For Photovoltaic Modules: Coherent Structure And Heat Shedding Amplification, Sarah Elizabeth Smith

Dissertations and Theses

Solar photovoltaic systems have become the fastest growing renewable technology in the last several years. However, large-scale systems are at the mercy of their external environments, where extreme heating and wind-flung debris impact their efficiency and useable life. The work in this dissertation presents studies aimed to both understand and mitigate for these effects by identifying the underlying physics which govern them. Exploring flow control as a tactic to combat environmental heating, collective work discusses the role of turbulent fluid dynamics within large-scale systems as pertains to convective heat transfer, turbulent structure formation, and particle-laden environments. Wind tunnel experiments on …

Barriers And Facilitators To Lifestyle Behavior Change And Goal Setting In Adolescents With Polycystic Ovary Syndrome., Manasa Gadiraju, Joy Y. Kim, Erin M. Green, Alexandra Macmillan Uribe, Honghui Chang, Tania S. Burgert, Melissa D. Olfert, Heidi Vanden Brink

Manuscripts, Articles, Book Chapters and Other Papers

PURPOSE: To identify barriers and facilitators to lifestyle modifications and goal setting and characterize goal setting for adolescents with polycystic ovary syndrome (PCOS).

METHODS: Retrospective chart review of registered dietitian nutritionist (RDN) nutrition notes from 118 adolescents with PCOS 11-21 years evaluated at a multi-specialty PCOS clinic. Goals, barriers, and facilitators were coded using open coding and a priori objectives and characterized for emerging themes using qualitative content analysis.

RESULTS: Five major themes of barriers and facilitators to behavior change emerged: interest and motivation, family involvement, resources and food environment, taste preferences, and self-efficacy. RDNs set ≥3 goals with 52%, …

A Contemporary Review On Heart Failure With Improved Ejection Fraction, Lingling Wu, Mario Rodriguez, Muzamil Khawaja, Errol Moras, Carl J Lavie, Gregg C Fonarow, W H Wilson Tang, Biykem Bozkurt, Chayakrit Krittanawong

Faculty, Staff and Students Publications

Heart failure is a complex condition caused by various etiologies that reduce cardiac output or increase cardiac pressures. It is classified by left ventricular ejection fraction, a key prognostic factor. New therapies, devices, and better management of secondary causes have improved outcomes. A recently identified group-those with heart failure and improved ejection fraction-shows better prognosis. This review explores its definition, causes, clinical significance, and management strategies.

Low-Energy Multiphoton Scattering At Tree-Level And One-Loop Order In A Homogeneous Electromagnetic Field, James Edwards, Ivan Ahumada Hernandez, Patrick Copinger

School of Engineering, Computing and Mathematics

We study low energy photons coupled to scalar and spinor matter in the presence of an arbitrary homogeneous electromagnetic field in a first-quantized (worldline) approach. Utilizing a Fock-Schwinger gauge for both the scattering photons and homogeneous background, simple compact expressions are found for both the photon- and background-dressed effective action and propagator in scalar and spinor quantum electrodynamics. The low-energy limit allows identification of the coupling of the scattering photons as one of an effective homogeneous superposition of their field strengths, with amplitudes following from application of a suitable linearization operator. To treat the linearization, several techniques are employed, including …

Newsletter 2025.11.24, Fcrh Honors Program

What's Going On, Honors? (2025-26)

No abstract provided.

Between Sovereignty And Commons: Legal Frameworks For Digital Data Governance In India, Anushka Sachan

Journal of Law and Public Policy

This legislative note critically examines the Indian Digital Personal Data Protection (DPDP) Act, 2023, with a focus on its provisions that imply data sovereignty and their implications for the governance of digital commons. Drawing on the seminal works on data commons, the note explores the conceptual and practical tensions between centralised data sovereignty, participatory, and decentralised models of data stewardship. While data sovereignty is often justified on grounds of national security and control, it may inadvertently hinder the development of inclusive and accountable frameworks for managing data as a public good.

Revisiting The Meaning Of 'Forests'—In Re: T.N. Godavarman Thirumulpad V Uoi, Gayathri D. Naik

Journal of Law and Public Policy

This Case Comment reflects on the contributions of the judiciary to forest governance and management through the use of continuous mandamus in the landmark case T.N. Godavarman v UoI. It offers insights into these contributions, particularly an expansion of the understanding of ‘forests’, by examining the latest judicial decision in the Godavarman series, which was on the protection of sacred groves in Rajasthan. The expansion of the definition of ‘forests’ to include sacred groves can help accord the protection and ensure the preservation of these small forest lands with rich biodiversity and religious and cultural significance.