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Articles 133891 - 133920 of 5210767

Full-Text Articles in Entire DC Network

Breaking Through The Strength-Ductility Trade-Off Of Lpbf-Produced Ti-Xnb Alloys From Mixed Powders Via Ω-Phase Induced Heterostructure, Jian Bo Jin, Shengfeng Zhou, Huan Yang, Junjie Yang, Zhiguo Zhang, Baisong Guo, Lai Chang Zhang Dec 2025

Breaking Through The Strength-Ductility Trade-Off Of Lpbf-Produced Ti-Xnb Alloys From Mixed Powders Via Ω-Phase Induced Heterostructure, Jian Bo Jin, Shengfeng Zhou, Huan Yang, Junjie Yang, Zhiguo Zhang, Baisong Guo, Lai Chang Zhang

Research outputs 2022 to 2026

Highlights Powder-mixed Ti-35Nb alloy produced by LPBF breaks through the strength-ductility trade-off. The ultimate strength, uniform elongation and Young’s modulus of heterostructured Ti-35Nb alloy are (806 ± 7) MPa, (18.0 ± 1.1)%, and (68 ± 6) GPa, respectively. In-situ laser re-melting improves elemental distribution uniformity in LPBF-produced powder-mixed Ti-xNb alloys. Optimized Nb content induces the phase transformation of β + α′ → β + ω in Ti-xNb alloy. Heterostructured β + ω/β enhances the strength-ductility synergy of Ti-35Nb alloy.

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Development And Validation Of An Interpretable Risk Prediction Model For The Early Classification Of Thalassemia, Jin Xin Lai, Jia Wei Tang, Shan Shan Gong, Ming Xiong Qin, Yu Lu Zhang, Quan Fa Liang, Li Yan Li, Zhen Cai, Liang Wang Dec 2025

Development And Validation Of An Interpretable Risk Prediction Model For The Early Classification Of Thalassemia, Jin Xin Lai, Jia Wei Tang, Shan Shan Gong, Ming Xiong Qin, Yu Lu Zhang, Quan Fa Liang, Li Yan Li, Zhen Cai, Liang Wang

Research outputs 2022 to 2026

Thalassemia is an inherited blood disorder. Current diagnostic methods mainly rely on sophisticated equipment and specifically trained technicians. This study aims to identify and genotype thalassemia by applying machine learning (ML) algorithms to routine blood parameters. This study recruited a derivation cohort of 31,311 individuals from four independent hospitals and developed eight machine learning (ML) models for the purpose. The performance of these models was compared using a set of evaluation metrics. An additional cohort of 2000 patients was recruited for external validation to assess the generalization of the models. The results demonstrated that the categorical boosting (CatBoost) model exhibited …

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Interpretive Prediction Of Hyperuricemia And Gout Patients Via Machine Learning Analysis Of Human Gut Microbiome, Jia Wei Tang, Alfred Chin Yen Tay, Liang Wang Dec 2025

Interpretive Prediction Of Hyperuricemia And Gout Patients Via Machine Learning Analysis Of Human Gut Microbiome, Jia Wei Tang, Alfred Chin Yen Tay, Liang Wang

Research outputs 2022 to 2026

Hyperuricemia (HUA) and gout result from imbalances in uric acid metabolism and are closely associated with the gut microbiota. Advanced analytical methods facilitate the exploration of microbiota complexity. In this study, 16S rRNA sequencing data from stool samples of 233 patients were thoroughly collected. Machine learning (ML) and Shapley Additive exPlanations (SHAP) interpretability algorithms were applied to identify core taxa and predict the metabolic functions. The results revealed that the high-contribution core taxa identified by SHAP in each group, such as Oscillospiraceae_UCG-005 and Rhodococcus provided the basis for ML prediction. Among the five classification models, Random Forest (RF) achieved the …

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Optimization Of Size And Siting Of Distributed Generation In Unbalanced Distribution Systems: A Literature Review, Pema Dorji, Stefan Lachowicz, Octavian Bass Dec 2025

Optimization Of Size And Siting Of Distributed Generation In Unbalanced Distribution Systems: A Literature Review, Pema Dorji, Stefan Lachowicz, Octavian Bass

Research outputs 2022 to 2026

Renewable energy sources (RES) are essential for meeting the rising global electricity demand while reducing greenhouse gas emissions from conventional generation. As traditional systems approach capacity saturation, the integration of RES into power grids becomes increasingly vital. However, the intermittent and variable nature of RES introduces significant technical, economic, and operational challenges. This review focuses on the optimal planning and integration of distributed generation in unbalanced distribution systems, which more accurately reflect real-world power network conditions. Emphasis is placed on siting and sizing strategies aimed at enhancing voltage stability, minimizing power losses, and reducing system costs and emissions. The review …

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Practical Recommendations On Stretching Exercise: A Delphi Consensus Statement Of International Research Experts, Konstantin Warneke, Ewan Thomas, Anthony J. Blazevich, José Afonso, David G. Behm, Paulo H. Marchetti, Gabriel S. Trajano, Masatoshi Nakamura, Francisco Ayala, Stefano Longo, Nicolas Babault, Sandro R. Freitas, Pablo B. Costa, Andreas Konrad, Antoine Nordez, Arnold Nelson, Astrid Zech, Anthony D. Kay, Olyvia Donti, Jan Wilke Dec 2025

Practical Recommendations On Stretching Exercise: A Delphi Consensus Statement Of International Research Experts, Konstantin Warneke, Ewan Thomas, Anthony J. Blazevich, José Afonso, David G. Behm, Paulo H. Marchetti, Gabriel S. Trajano, Masatoshi Nakamura, Francisco Ayala, Stefano Longo, Nicolas Babault, Sandro R. Freitas, Pablo B. Costa, Andreas Konrad, Antoine Nordez, Arnold Nelson, Astrid Zech, Anthony D. Kay, Olyvia Donti, Jan Wilke

Research outputs 2022 to 2026

Background: Stretching has wide appeal, but there seems to exist some mismatch between its purported applications and what the evidence shows. There is compelling evidence for some stretching applications, but for others, the evidence seems heterogeneous or unsupportive. The discrepancies even affect some systematic reviews, possibly due to heterogeneous eligibility criteria and search strategies. This consensus paper seeks to unify the divergent findings on stretching and its implications for both athletic performance and clinical practices by delivering evidence-based recommendations. Methods: A panel of 20 experts with a blend of practical experience and scholarly knowledge was assembled. The panel meticulously reviewed …

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Prevalence And Trends Of Coexisting Forms Of Malnutrition And Its Associated Factors Among Children Aged 6–59 Months In South And Southeast Asia, 1996–2022: A Cross-Sectional Time Series Study, Wenjie Guo, Maggie Zgambo, Sanmei Chen, Yoko Shimpuku Dec 2025

Prevalence And Trends Of Coexisting Forms Of Malnutrition And Its Associated Factors Among Children Aged 6–59 Months In South And Southeast Asia, 1996–2022: A Cross-Sectional Time Series Study, Wenjie Guo, Maggie Zgambo, Sanmei Chen, Yoko Shimpuku

Research outputs 2022 to 2026

Background: South and Southeast Asia face severe malnutrition in children under five, with coexisting forms of malnutrition (CFM) exacerbating mortality risks and posing greater challenges than isolated forms of malnutrition. We aimed to assess the prevalence, trends, and factors of CFM among children aged 6–59 months in South and Southeast Asian countries and the entire region. Methods: We used anthropometric and hemoglobin data from 515,170 children aged 6–59 months in seven low- and middle-income South and Southeast Asian countries, based on Demographic and Health Surveys conducted between 1996 and 2022. Weighted multivariable logistic regression was performed to identify the sociodemographic …

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Relationship Between Cytomegalovirus Antibody Levels And Cognitive Performance Is Dependent On Age And Genetic Risk, Michael Vacher, Silvia Lee, Patricia Price, Phuongnhi Ha, Shelley Waters, Simon M. Laws Dec 2025

Relationship Between Cytomegalovirus Antibody Levels And Cognitive Performance Is Dependent On Age And Genetic Risk, Michael Vacher, Silvia Lee, Patricia Price, Phuongnhi Ha, Shelley Waters, Simon M. Laws

Research outputs 2022 to 2026

Human cytomegalovirus (CMV) is endemic worldwide. It is often acquired in childhood and persists throughout adult life. CMV is linked with several diseases of aging, but associations with cognitive performance are not consistent. Here we address whether this may reflect a dependence on putative genetic determinants, Apolipoprotein E (APOE) ε4 and Tumour Necrosis Factor (TNF), and/or the age of the subjects tested. CMV-reactive antibodies were quantitated in 419 individuals aged 71.7 [53.2—89.1] years, drawn from the Australian Imaging, Biomarker & Lifestyle (AIBL) study. Cognitive composite scores, covering five domains, a global score of cognitive performance, brain amyloid-β (Aβ) burden and …

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Sediment Burial Negatively Impacts The Growth Of Seagrass Posidonia Sinuosa, Chanelle Webster, Nicole Said, Natasha Dunham, Simone Strydom, Kathryn Mcmahon Dec 2025

Sediment Burial Negatively Impacts The Growth Of Seagrass Posidonia Sinuosa, Chanelle Webster, Nicole Said, Natasha Dunham, Simone Strydom, Kathryn Mcmahon

Research outputs 2022 to 2026

Burial disturbances affect foundation plant species in marine ecosystems. Deposition of dredge spoil can bury seagrass meadows yet we have limited threshold information to predict the trajectory of impact from burial or possible recovery. To investigate the response to burial by dredge spoil, established seagrass ramets of Posidonia sinuosa were collected from a population in Western Australia and exposed to cutter suction dredge spoil sediment. Plant responses were measured during a burial phase after 2, 4 and 8 weeks to assess the influence of duration to burial depths (0, 1, 4, 8 and 16 cm). Sediments were then removed, and …

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Soil Organic Carbon Depth Profiles And Centennial And Millennial Decay Rates In Tidal Marsh, Mangrove And Seagrass Blue Carbon Ecosystems, Nerea Piñeiro-Juncal, Miguel Ángel Mateo, Carmen Leiva-Dueñas, Eduard Serrano, Karina Inostroza, Montserrat Soler, Eugenia T. Apostolaki, Paul Lavery, Carlos M. Duarte, Anna Lafratta, Oscar Serrano Dec 2025

Soil Organic Carbon Depth Profiles And Centennial And Millennial Decay Rates In Tidal Marsh, Mangrove And Seagrass Blue Carbon Ecosystems, Nerea Piñeiro-Juncal, Miguel Ángel Mateo, Carmen Leiva-Dueñas, Eduard Serrano, Karina Inostroza, Montserrat Soler, Eugenia T. Apostolaki, Paul Lavery, Carlos M. Duarte, Anna Lafratta, Oscar Serrano

Research outputs 2022 to 2026

The management of coastal blue carbon ecosystems can contribute to mitigate anthropogenic greenhouse gas emissions. However, limited information on soil organic carbon (OC) decay rates in tidal marsh, mangrove, and seagrass soils hinders their inclusion in climate strategies and carbon-crediting schemes. Here, we analyzed downcore OC trends in 3761 soil cores from blue carbon ecosystems worldwide. A decrease in OC content with soil depth was measured in 63% of the cores, whereas stable and increasing trends were observed in 22% and 15% of the cores, respectively. Based on 85 profiles where OC decay could be modelled, the OC decay rate …

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The First Year Of Assisted Dying In New Zealand Through The Lens Of Healthcare Professionals Not Directly Involved In The Process, Waqas Arshad, Aida Dehkhoda, Melissa Carey, David B. Menkes, Nicholas Hoeh, Frederick Sundram, Rosemary Frey, Gary Cheung Dec 2025

The First Year Of Assisted Dying In New Zealand Through The Lens Of Healthcare Professionals Not Directly Involved In The Process, Waqas Arshad, Aida Dehkhoda, Melissa Carey, David B. Menkes, Nicholas Hoeh, Frederick Sundram, Rosemary Frey, Gary Cheung

Research outputs 2022 to 2026

Background: New Zealand’s End of Life Choice Act 2019 was enacted in 2021, allowing terminally ill people experiencing unbearable suffering to request assisted dying if they are expected to die within six months. Healthcare professionals not directly involved in assisted dying provision may have unique perspectives on implementation, yet this remains under-explored. Methods: This qualitative study was conducted between June and November 2022. We used purposive and snowball sampling to recruit potential participants through various sources, including the Ministry of Health’s assisted dying training and communication email list. A multidisciplinary research team developed a semi-structured interview guide. The individual interviews …

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Design Of A Novel Robust Adaptive Fractional-Order Model Predictive Controller For Boost Converter Using Grey Wolf Optimization Algorithm, Chao Peng, Seyyed Morteza [email protected] Ghamari, Hasan Mollaee, Omid Rezaei Dec 2025

Design Of A Novel Robust Adaptive Fractional-Order Model Predictive Controller For Boost Converter Using Grey Wolf Optimization Algorithm, Chao Peng, Seyyed Morteza [email protected] Ghamari, Hasan Mollaee, Omid Rezaei

Research outputs 2022 to 2026

Boost converters play a crucial role in power electronics but present control challenges due to their non-minimum phase behavior and nonlinear dynamics at high switching frequencies. To address these issues, this work proposes a Fractional-order adaptive Model Predictive Control (FO-MPC) framework incorporating Exponential Regressive Least Squares (ERLS) for system identification. Traditional MPC frameworks often rely on accurate mathematical models, which are difficult to obtain in real-world scenarios. This adaptive modelling approach based on ERLS identification method eliminates the need for precise system models, improving robustness and adaptability under parameter variations. Additionally, a FO derivative term enhances damping, stability, and noise …

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Eccentric-Only Versus Concentric-Only Isokinetic Strength Training Effects On Maximal Voluntary Eccentric, Concentric And Isometric Contraction Strength: A Systematic Review And Meta-Analysis, Darjan Spudić, Kazunori Nosaka Dec 2025

Eccentric-Only Versus Concentric-Only Isokinetic Strength Training Effects On Maximal Voluntary Eccentric, Concentric And Isometric Contraction Strength: A Systematic Review And Meta-Analysis, Darjan Spudić, Kazunori Nosaka

Research outputs 2022 to 2026

Background: Conflicting results have been reported regarding the effects of resistance exercise training with eccentric (lengthening muscle) versus concentric (shortening muscle) contractions on changes in maximal voluntary contraction (MVC) strength assessed by different contraction modes. Objective: The main objective of this systematic review with meta-analyses was to compare the effectiveness of maximal isokinetic eccentric-only and concentric-only strength training for changes in maximal voluntary eccentric (MVCECC), concentric (MVCCON), and isometric contraction (MVCISO) strength in healthy adults. Methods: We conducted a systematic search in PubMed, SPORTDiscus, and Google Scholar from February to March 2024 for studies that met the following criteria: (1) …

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Caveolin 1 And 2 Enhance The Proliferative Capacity Of Bcam-Positive Corneal Progenitors, Yuzuru Sasamoto, Shoko Kiritoshi, Catherine A.A. Lee, Yoshiko Fukuda, Gabrielle Martin, Bruce R. Ksander, Markus H. Frank, Natasha Y. Frank Dec 2025

Caveolin 1 And 2 Enhance The Proliferative Capacity Of Bcam-Positive Corneal Progenitors, Yuzuru Sasamoto, Shoko Kiritoshi, Catherine A.A. Lee, Yoshiko Fukuda, Gabrielle Martin, Bruce R. Ksander, Markus H. Frank, Natasha Y. Frank

Research outputs 2022 to 2026

Caveolin (CAV) 1 and 2 are integral membrane proteins that constitute major components of small membrane pouches termed caveolae. While several functions have been described in other tissues, the roles of CAV1 and CAV2 in the ocular surface have remained unknown. In the current study, we investigated the expression and function of CAV1 and CAV2 in the human cornea. We found CAV1 and CAV2 to be preferentially expressed by proliferative Basal Cell Adhesion Molecule (BCAM)-positive progenitor cells along the entire limbal and corneal basal epithelial layer. Functional gene knockdown studies reveal that BCAM, BCAM co-expressed Laminin α5 (LAMA5) and Laminin …

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Effects Of Short- And Long-Term Exercise Training On Cancer Cells In Vitro: Insights Into The Mechanistic Associations, Francesco Bettariga, Dennis R. Taaffe, Daniel A. Galvão, Robert U. Newton Dec 2025

Effects Of Short- And Long-Term Exercise Training On Cancer Cells In Vitro: Insights Into The Mechanistic Associations, Francesco Bettariga, Dennis R. Taaffe, Daniel A. Galvão, Robert U. Newton

Research outputs 2022 to 2026

Exercise is a therapeutic approach in cancer treatment, providing several benefits. Moreover, exercise is associated with a reduced risk for developing a range of cancers and for their recurrence, as well as with improving survival, even though the underlying mechanisms remain unclear. Preclinical and clinical evidence shows that the acute effects of a single exercise session can suppress the growth of various cancer cell lines in vitro. This suppression is potentially due to altered concentrations of hormones (e.g., insulin) and cytokines (e.g., tumor necrosis factor alpha and interleukin 6) after exercise. These factors, known to be involved in tumorigenesis, may …

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Exercise Medicine As Adjunct Therapy During Radiation For Cancer Of The Prostate To Improve Treatment Efficacy – Protocol For The Eradicate Study: A Phase Ii Randomised Controlled Trial, Oliver Schumacher, Robert U. Newton, Colin Tang, Raphael Chee, Sjoerd B. Vos, Ronny S. Low, David Joseph, Dennis R. Taaffe, Daniel A. Galvão Dec 2025

Exercise Medicine As Adjunct Therapy During Radiation For Cancer Of The Prostate To Improve Treatment Efficacy – Protocol For The Eradicate Study: A Phase Ii Randomised Controlled Trial, Oliver Schumacher, Robert U. Newton, Colin Tang, Raphael Chee, Sjoerd B. Vos, Ronny S. Low, David Joseph, Dennis R. Taaffe, Daniel A. Galvão

Research outputs 2022 to 2026

Background: Tumour hypoxia resulting from inadequate perfusion is common in many solid tumours, including prostate cancer, and constitutes a major limiting factor in radiation therapy that contributes to treatment resistance. Emerging research in preclinical animal models indicates that exercise has the potential to enhance the efficacy of cancer treatment by modulating tumour perfusion and reducing hypoxia; however, evidence from randomised controlled trials is currently lacking. The ‘Exercise medicine as adjunct therapy during RADIation for CAncer of the prostaTE’ (ERADICATE) study is designed to investigate the impact of exercise on treatment response, tumour physiology, and adverse effects of treatment in prostate …

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Exploring And Validating Associations Between Six Systemic Inflammatory Indices And Ischemic Stroke In A Middle-Aged And Old Chinese Population, Yulu Zheng, Zheng Guo, Jingzheng Wang, Zhiyuan Wu, Xiaolin Chen, Yahong Zhu, Guangle Shan, Haifeng Hou, Xingang Li Dec 2025

Exploring And Validating Associations Between Six Systemic Inflammatory Indices And Ischemic Stroke In A Middle-Aged And Old Chinese Population, Yulu Zheng, Zheng Guo, Jingzheng Wang, Zhiyuan Wu, Xiaolin Chen, Yahong Zhu, Guangle Shan, Haifeng Hou, Xingang Li

Research outputs 2022 to 2026

Background: Inflammation and maladaptive immune mechanisms have been substantiated as integral components in the critical pathological processes of the injury cascade in ischemic stroke (IS). This study aimed to explore the associations between six systemic inflammatory indices and IS in a Chinese population. Methods: This was a case-control study based on the retrospective review of electronic medical records from two hospitals in Shandong Province, China. Systemic inflammatory indices, including the systemic inflammation response index (SIRI), systemic immune inflammation index (SII), pan-immune-inflammation value (PIV), neutrophil lymphocyte ratio (NLR), platelet lymphocyte ratio (PLR), and lymphocyte monocyte ratio (LMR), were calculated. Logistic regression …

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Industry Return Predictability Using Health Policy Uncertainty, Thach Pham, Deepa Bannigidadmath, Robert Powell Dec 2025

Industry Return Predictability Using Health Policy Uncertainty, Thach Pham, Deepa Bannigidadmath, Robert Powell

Research outputs 2022 to 2026

This paper examines how a change in health policy uncertainty affects US industry returns using monthly data from January 1985 to September 2020. We employ in-sample and out-of-sample analyses, and we find evidence that 25 out of 49 considered industries are predictable during the health crisis periods, including severe acute respiratory syndrome and the ongoing coronavirus pandemic. The out-of-sample tests corroborate the evidence for the in-sample predictability. Furthermore, using a mean–variance utility function-based trading strategy, we observe that investors can use this simple tool for their trading strategies and make profits from 2.99 to 11.44% per annum. Our findings are …

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Is Maternal Diabetes During Pregnancy Associated With Neurodevelopmental, Cognitive And Behavioural Outcomes In Children? Insights From Individual Participant Data Meta-Analysis In Ten Birth Cohorts, Rachelle A. Pretorius, Demetris Avraam, Mònica Guxens, Jordi Julvez, Jennifer R. Harris, Johanna Thorbjornsrud Nader, Tim Cadman, Ahmed Elhakeem, Katrine Strandberg-Larsen, Hanan El Marroun, Serena Defina, Tiffany C. Yang, Rosie Mceachan, John Wright, Jesús Ibarluzea, Loreto Santa-Marina, Juana Mari Delgado, Marisa Rebagliato, Marie Aline Charles, Chloe Vainqueur, Silvia Maritano, Daniela Zugna, Wen Lun Yuan, Barbara Heude, Rae Chi Huang Dec 2025

Is Maternal Diabetes During Pregnancy Associated With Neurodevelopmental, Cognitive And Behavioural Outcomes In Children? Insights From Individual Participant Data Meta-Analysis In Ten Birth Cohorts, Rachelle A. Pretorius, Demetris Avraam, Mònica Guxens, Jordi Julvez, Jennifer R. Harris, Johanna Thorbjornsrud Nader, Tim Cadman, Ahmed Elhakeem, Katrine Strandberg-Larsen, Hanan El Marroun, Serena Defina, Tiffany C. Yang, Rosie Mceachan, John Wright, Jesús Ibarluzea, Loreto Santa-Marina, Juana Mari Delgado, Marisa Rebagliato, Marie Aline Charles, Chloe Vainqueur, Silvia Maritano, Daniela Zugna, Wen Lun Yuan, Barbara Heude, Rae Chi Huang

Research outputs 2022 to 2026

Background: Growing evidence shows that dysregulated metabolic intrauterine environments can affect offspring’s neurodevelopment and behaviour. However, the results of individual cohort studies have been inconsistent. We aimed to investigate the association between maternal diabetes before pregnancy and gestational diabetes mellitus (GDM) with neurodevelopmental, cognitive and behavioural outcomes in children. Methods: Harmonised data from > 200 000 mother-child pairs across ten birth cohorts in Europe and Australia were available. Mother-child pairs were included for analysis to determine whether GDM was recorded (yes or no) and whether at least one neurodevelopmental, cognitive and behavioural outcome was available in children aged 3 to 13 …

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Optimization Of Energy Management In Malaysian Microgrids Using Fuzzy Logic-Based Ems Scheduling Controller, Mohammad Nur-E-Alam, Tarek Abedin, Nur Aini Samsudin, Jana Petrů, Abdulwasa Bakr Barnawi, Manzoore Elahi M. Soudagar, T. M.Yunus Khan, Muhammad Nasir Bashir, Mohammad Aminul Islam, Boon Kar Yap, Tiong Sieh Kiong Dec 2025

Optimization Of Energy Management In Malaysian Microgrids Using Fuzzy Logic-Based Ems Scheduling Controller, Mohammad Nur-E-Alam, Tarek Abedin, Nur Aini Samsudin, Jana Petrů, Abdulwasa Bakr Barnawi, Manzoore Elahi M. Soudagar, T. M.Yunus Khan, Muhammad Nasir Bashir, Mohammad Aminul Islam, Boon Kar Yap, Tiong Sieh Kiong

Research outputs 2022 to 2026

The microgrid (MG) faces significant security issues due to the two-way power and information flow. Integrating an Energy Management System (EMS) to balance energy supply and demand in Malaysian microgrids, this study designs a Fuzzy Logic Controller (FLC) that considers intermittent renewable sources and fluctuating demand patterns. FLC offers a flexible solution to energy scheduling effectively assessed by MATLAB/Simulink simulations. The microgrid consists of PV, battery, grid, and load. A Maximum Power Point Tracking (MPPT) controller helps to extract the maximum PV output and manages the power storage by providing or absorbing excess power. System analysis is performed by observing …

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Perfectionism And Compulsive Exercise: A Systematic Review And Preliminary Meta-Analysis, Elizabeth Bills, Shannon R. Muir, Rose Stackpole, Sarah J. Egan Dec 2025

Perfectionism And Compulsive Exercise: A Systematic Review And Preliminary Meta-Analysis, Elizabeth Bills, Shannon R. Muir, Rose Stackpole, Sarah J. Egan

Research outputs 2022 to 2026

Purpose: There is a consistent link between perfectionism and compulsive exercise, and both are implicated in the maintenance of eating disorders, however no meta-analysis to date has quantified this relationship. We hypothesised that there would be significant, small-moderate pooled correlations between perfectionism dimensions and compulsive exercise. Methods: Published, peer-reviewed articles with standardised measures of perfectionism and the Compulsive Exercise Test were included. There were 7 studies included (N = 3117 participants, M age = 21.78 years, 49% female). Results: Total perfectionism (r = 0.37), perfectionistic strivings (r = 0.33), and perfectionistic concerns (r = 0.32) had significant pooled positive associations …

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Profiling Of Igg N-Glycosylation For Axial Spondyloarthritis And Other Rheumatic Diseases, Xiaojia Xu, Zhixian Chen, Manshu Song, Zhiduo Hou, Lois Balmer, Chunbin Zhou, Yayi Huang, Haifeng Hou, Wei Wang, Ling Lin Dec 2025

Profiling Of Igg N-Glycosylation For Axial Spondyloarthritis And Other Rheumatic Diseases, Xiaojia Xu, Zhixian Chen, Manshu Song, Zhiduo Hou, Lois Balmer, Chunbin Zhou, Yayi Huang, Haifeng Hou, Wei Wang, Ling Lin

Research outputs 2022 to 2026

Background: Axial spondyloarthritis (axSpA) is an inflammatory rheumatic disease with challenges in diagnosis and disease activity assessment. While alterations in immunoglobulin G (IgG) N-glycosylation have been observed in varied rheumatic diseases, those in axSpA remains unclear. This study aims to explore the role of IgG N-glycan profiles in diagnosis and disease activity of axSpA. Methods: A clinical case-control study was conducted involving patients with axSpA (n = 138), systemic lupus erythematosus (n = 102), rheumatoid arthritis (n = 106), osteoarthritis (n = 33), gout (n = 41) and healthy controls (n = 117). Ultra-performance liquid chromatography was employed to analyze …

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The Effect Of Prednisolone Ingestion And Acute Exercise On Lipocalin-2 And Its Variants In Young Men: A Pilot Randomised Crossover Study, Carlie Bauer, Rhiannon K. Patten, Qiyang Sun, Haoyun Li, Daniels Konja, Mary Woessner, Xuzhu Lin, Andrew Garnham, David L. Hare, Peter R. Ebeling, Marc Sim, Joshua R. Lewis, Yu Wang, Lewan Parker, Itamar Levinger Dec 2025

The Effect Of Prednisolone Ingestion And Acute Exercise On Lipocalin-2 And Its Variants In Young Men: A Pilot Randomised Crossover Study, Carlie Bauer, Rhiannon K. Patten, Qiyang Sun, Haoyun Li, Daniels Konja, Mary Woessner, Xuzhu Lin, Andrew Garnham, David L. Hare, Peter R. Ebeling, Marc Sim, Joshua R. Lewis, Yu Wang, Lewan Parker, Itamar Levinger

Research outputs 2022 to 2026

Lipocalin-2 (LCN2) has three main variants; polyaminated (hLCN2) and non-polyaminated (C87A and R81E). The polyaminated form is proposed to positively influence energy control, whereas the non-polyaminated forms negatively impact energy control in mice. Glucocorticoids negatively affect glucose regulation and exercise has a positive effect. We hypothesise that glucocorticoids will suppress, while exercise will increase hLCN2, and decrease C87A and R81E, which will be associated with improved insulin sensitivity. In a randomised crossover design, nine young healthy men (aged 27.8 ± 4.9 years; BMI 24.4 ± 2.4 kg/m2) completed 30 min of high-intensity aerobic exercise (90–95% heart rate reserve) after glucocorticoid …

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The Experience Of Mothers Of Autistic Children With A Pathological Demand Avoidance Profile: An Interpretative Phenomenological Analysis, Sam Curtis, Elizabeth Izett Dec 2025

The Experience Of Mothers Of Autistic Children With A Pathological Demand Avoidance Profile: An Interpretative Phenomenological Analysis, Sam Curtis, Elizabeth Izett

Research outputs 2022 to 2026

Purpose: Emergent research literature has identified emotional and behavioural challenges for autistic children with a pathological demand avoidance profile. However, understanding of their parents’ experience is limited. This study aimed to explore the experience of parents of autistic children with a pathological demand avoidance profile. Methods: Semi-structured interviews were completed with ten parents of autistic children with a pathological demand avoidance profile, aged between 5 and 11 years (M = 8.5, SD = 1.90). All participants were mothers, aged 33–50 years (M = 42, SD = 5.35). To explore what meaning participants gave to their lived experience, an interpretative phenomenological …

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The Significant Impact Of Hot Isostatic Pressing On The Corrosion Behavior Of Ti-6al-4v Alloy Prepared By Electron Beam Powder Bed Fusion, Hongyu Zheng, Yun Bai, Wentao Hou, Zirong Zhai, Lai Chang Zhang, Shujun Li, Rui Yang Dec 2025

The Significant Impact Of Hot Isostatic Pressing On The Corrosion Behavior Of Ti-6al-4v Alloy Prepared By Electron Beam Powder Bed Fusion, Hongyu Zheng, Yun Bai, Wentao Hou, Zirong Zhai, Lai Chang Zhang, Shujun Li, Rui Yang

Research outputs 2022 to 2026

This work investigated the effect of hot isostatic pressing (HIP) on the corrosion behavior of Ti-6Al-4V samples prepared by electron beam powder bed fusion (EB-PBF). After the HIP treatment, the TiO2 content decreased but the growth rate of passivation films increased, leading to increase in internal defect density, thereby degrading the corrosion resistance. Amongst the different factors impacted by HIP including pore defects, β-phase, texture and morphology of α-phase, the morphology of α-phase played a dominant role in determining the corrosion performance of EB-PBF processed alloy.

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A Cross-Sectional Audit Of The Australian Community Food Environment Highlights The Prominent Role Of Chain Food Outlets, Claire Elizabeth Pulker, Lucy Meredith Butcher, Frith Klug, Clare Whitton, Gina S.A. Trapp Dec 2025

A Cross-Sectional Audit Of The Australian Community Food Environment Highlights The Prominent Role Of Chain Food Outlets, Claire Elizabeth Pulker, Lucy Meredith Butcher, Frith Klug, Clare Whitton, Gina S.A. Trapp

Research outputs 2022 to 2026

Background: Food retail and food service outlets can be part of a chain, or independently operated. Chain food outlets are likely to have the most influence over community food environments but have not been routinely identified in studies which map and monitor access to food, highlighting an important knowledge gap. This study aimed to identify the food retail and food service outlets present within metropolitan Perth, including presence of chain and independent food outlets; and examine differences across local governments. Methods: A nutrition-focused classification framework was applied to all food businesses registered by 32 local governments in Perth, Western Australia, …

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A National Survey Of Osteopaths’ Conceptions Of Practice In France: Structural Validity Of The Osteo-Taqfr And The Tendency Toward Technical Rationality, Oliver P. Thomson, Loïc Treffel, Agathe Wagner, Erwann Jacquot, Jerry Draper-Rodi, Chantal Morin, Brett Vaughan Dec 2025

A National Survey Of Osteopaths’ Conceptions Of Practice In France: Structural Validity Of The Osteo-Taqfr And The Tendency Toward Technical Rationality, Oliver P. Thomson, Loïc Treffel, Agathe Wagner, Erwann Jacquot, Jerry Draper-Rodi, Chantal Morin, Brett Vaughan

Research outputs 2022 to 2026

Background: Despite the growing popularity of osteopathy in France, little is known about how French osteopaths conceptualise key aspects of their practice, including skills, knowledge, and decision-making. This study aimed to adapt and validate the Osteopaths' Therapeutic Approaches Questionnaire (Osteo-TAQ) for use in a French osteopathic population (Osteo-TAQfr) and to examine the professional profile and core elements of clinical practice among French osteopaths. The first objective was to establish the psychometric properties of the Osteo-TAQfr within a French osteopathic population. The second aim was to explore French osteopaths’ conceptions of practice and their approach to patient care, thereby contributing to …

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Alzheimer’S Disease Biological Pet Staging Using Plasma P217+Tau, Azadeh Feizpour, Vincent Doré, Natasha Krishnadas, Pierrick Bourgeat, James D. Doecke, Ziad S. Saad, Gallen Triana-Baltzer, Simon M. Laws, Rosita Shishegar, Kun Huang, Christopher Fowler, Larry Ward, Colin Masters, Jurgen Fripp, Hartmuth Kolb, Victor Villemagne, Christopher Rowe Dec 2025

Alzheimer’S Disease Biological Pet Staging Using Plasma P217+Tau, Azadeh Feizpour, Vincent Doré, Natasha Krishnadas, Pierrick Bourgeat, James D. Doecke, Ziad S. Saad, Gallen Triana-Baltzer, Simon M. Laws, Rosita Shishegar, Kun Huang, Christopher Fowler, Larry Ward, Colin Masters, Jurgen Fripp, Hartmuth Kolb, Victor Villemagne, Christopher Rowe

Research outputs 2022 to 2026

Background: Plasma phospho-tau biomarkers, such as p217+tau, excel at identifying Alzheimer’s disease (AD) neuropathology. However, their ability to substitute for tau PET to identify AD biological stage is unclear. Methods: Participants included 248 cognitively unimpaired (CU) and 227 cognitively impaired (CI) individuals, with Janssen plasma p217+tau Simoa® assay, 18F-NAV4694 Aβ-PET (A) and 18F-MK6240 tau-PET (T) data. Biological PET stages were defined according to the Revised Criteria for Diagnosis and Staging of Alzheimer’s Disease (2024): Initial (A + T-), Early (A + TMTL +), Intermediate (A + TMOD +), and Advanced (A + THIGH +). The threshold for A+ was 25 …

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Implementing Modified Constraint-Induced Movement Therapy After Stroke In An Early-Supported Discharge Rehabilitation Service: A Process Evaluation Using Re-Aim Quest, Ashan Weerakkody, Erin Godecke, Barby Singer Dec 2025

Implementing Modified Constraint-Induced Movement Therapy After Stroke In An Early-Supported Discharge Rehabilitation Service: A Process Evaluation Using Re-Aim Quest, Ashan Weerakkody, Erin Godecke, Barby Singer

Research outputs 2022 to 2026

Background: Modified constraint-induced movement therapy (mCIMT) improves upper limb (UL) function after stroke. Despite extensive evidence supporting its efficacy and multiple clinical practice guidelines recommending its provision, very few eligible stroke survivors receive mCIMT internationally. A multi-modal behaviour change intervention, guided by the Theoretical Domains Framework (TDF) and Behaviour Change Wheel, was implemented across a large early-supported discharge (ESD) rehabilitation service in Perth, Australia, to increase delivery of mCIMT within existing resources. As part of this iterative implementation process, qualitative data from stroke survivors, carers, clinicians and managers informed program adaptations to support sustained mCIMT delivery. This study aimed to …

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Prevalence Of Mental Illness, Substance Use Disorder, And Dual Diagnosis Among Adults In Custody, Darcy J. Coulter, Lindsay A. Pearce, Matthew Legge, Jesse T. Young, David B. Preen, Ed C. Heffernan, Jocelyn D. Jones, Stuart A. Kinner Dec 2025

Prevalence Of Mental Illness, Substance Use Disorder, And Dual Diagnosis Among Adults In Custody, Darcy J. Coulter, Lindsay A. Pearce, Matthew Legge, Jesse T. Young, David B. Preen, Ed C. Heffernan, Jocelyn D. Jones, Stuart A. Kinner

Research outputs 2022 to 2026

Background: The prevalence of mental illness, substance use disorders, and their dual diagnosis is disproportionately high among people in prisons compared to the community. Accurate prevalence estimates are required to inform resourcing of prison health services and reduce the risk of harm to people experiencing these conditions. Existing estimates, where available, often rely on only one data source. Method: We used three data sources – self-reported history of diagnoses, in-prison medical records, and administrative data to estimate the prevalence of mental illness, substance use disorder, and dual diagnosis among two large cohorts of non-Indigenous and Aboriginal and Torres Strait Islander …

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The Effect Of Muscle Warm-Up On Voluntary And Evoked Force-Time Parameters: A Systematic Review And Meta-Analysis With Meta-Regression, Cody J. Wilson, João Pedro Nunes, Anthony J. Blazevich Dec 2025

The Effect Of Muscle Warm-Up On Voluntary And Evoked Force-Time Parameters: A Systematic Review And Meta-Analysis With Meta-Regression, Cody J. Wilson, João Pedro Nunes, Anthony J. Blazevich

Research outputs 2022 to 2026

Background: While muscle contractility increases with muscle temperature, there is no consensus on the best warm-up protocol to use before resistance training or sports exercise due to the range of possible warm-up and testing combinations available. Therefore, the objective of the current study was to determine the effects of different warm-up types (active, exercise-based vs. passive) on muscle function tested using different activation methods (voluntary vs. evoked) and performance test criteria (maximum force vs. rate-dependent contractile properties), with consideration of warm-up task specificity (specific vs. non-specific), temperature measurement method (muscle vs. skin), baseline temperatures, and subject-specific variables (training status and …

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