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Re: Butte Priority Soils Operable Unit (Bpsou) Final Reclamation Improvement Sites Field Sampling And Investigation Plan (Fsp): Bres No. 45 – Garfield, Mike Mcanulty

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Annual Alumni Mixer, Latin American Law Students Association (Lalsa)

Student Organizations

Monday, October 6, 2025

Mmu: 10/06/25-10/12/25, Student Bar Association

Monday Morning Update

This Week @ NDLS

Mass Times

Commons Daily Menu

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General Announcements

Investigating Factors Influencing Organic Chemistry Learners' Explanation Sophistication And Representational Competence, Caroline J. Crowder

USF Tampa Graduate Theses and Dissertations

The research presented in this dissertation has two themes: organic chemistry learners’ written explanations and representational competence. Chapters 3 and 4 explore how organic chemistry learners construct explanations of reaction mechanisms, specifically focusing on electrophile and nucleophile components. Chapter 5 investigates organic chemistry learners’ representational competence skills and the relationship between these skills and their performance in the course.

Understanding reaction mechanisms is critical for success in organic chemistry, yet learners often struggle to reason beyond explicit, surface-level features. Constructed-response prompts that ask learners to explain what is happening in a reaction mechanism and why it occurs can provide insight …

Rescue Epilepsy Medication And Training: A Comparison Between Midazolam Use, Guidelines, Clinical Practice, And Possibilities In The Uk And Norway, Rohit Shankar

Peninsula Medical School

Objectives: Status epilepticus (SE) is a prolonged epileptic seizure carrying significant risk of long-term disability and death. Rescue therapies are prescribedfor prehospital administration to terminate SE. This study compared prescribingpractices of rescue therapies of midazolam in the UK and Norway.Methods: A cross-sectional, online, 21-item Likert-style survey was administeredto epilepsy professionals in the UK circulated via ILAE/ESNA and in Norway viaILAE/Epilepsinet using a non-discriminatory exponential snowballing techniqueleading to non-probability sampling. Data were collected anonymously and analyzed using descriptive statistics, Mann–Whitney, Chi-square, and Fisher's exact tests. Significance was accepted at p<0.05.Results: All 86 UK and 53 Norway respondents identified buccal midazolam as the first-line rescue medication choice in the community for prolonged and/or generalized tonic–clonic seizures. Norwegian respondents had significantly more experience in epilepsy-related work (p=0.002), were more likely to have a larger caseload on buccal midazolam (p<0.001), prescribed higher midazolam doses (p<0.001), and provided training yearly (p<0.001). UK respondents were more likely to delegate rescue medication prescribing to primary care (p=0.006) and reviewed emergency management plans more frequently (p=0.006). There was an inter-country difference in the period of midazolam non-use that respondents required before withdrawing from treatment plans (p<0.001). Concern about inappropriate use of buccal midazolam was similarly high in both countries.Significance: This study compared epilepsy professionals in two neighboringhigh-income countries. Findings suggest an urgent need for international guidelines to recommend best practices on prescribing doses and withdrawal of buccal midazolam. The potential abuse of buccal midazolam by patients and carers warrants further investigation.

Understanding The Role Of Street Medicine In Harm Reduction: A Case Study Of Street Medicine St. Louis, Ari Gzesh, Jeremiah S Truel, Danielle R Adams, Luke Zabotka, Sara Malone, Nathanial S Nolan

2020-Current year OA Pubs

BACKGROUND: Homelessness results from, and exacerbates, various social determinants of health, including poverty, racism, and inadequate healthcare access, which are further compounded by physical and mental health challenges. The street medicine movement seeks to address these disparities by providing direct medical care and harm reduction services to unsheltered homeless in low-barrier settings. The development of trust is critical to providing this form of care. Few studies have sought to understand the factors influencing trust development in street medicine encounters.

METHODS: This case study of Street Medicine St. Louis aims to explore the factors that influence trust and how trust development …

Apoe-Calypse Tau: Apoe-Tau Synergy In Alzheimer's Disease, Matthew Paul Lennol, Chiara Bordier, Léana Kamelher, Jason D Ulrich, David M Holtzman, Maud Gratuze

2020-Current year OA Pubs

Alzheimer's disease (AD), the most common cause of dementia, is characterized by the accumulation of amyloid-β (Aβ) in senile plaques and abnormally hyperphosphorylated tau proteins in neurofibrillary tangles. While much of the research has focused on Aβ, tau-mediated neurodegeneration is more closely associated with synaptic loss and cognitive decline in AD, emphasizing the need for a deeper understanding of tau pathology. In this context, the interaction between tau and APOE, particularly the main genetic risk factor for AD APOE ε4, remains underexplored. APOE encodes apolipoprotein E (apoE), a protein important in lipid metabolism. In addition to promoting Aβ deposition, emerging …

Investigation Of Lncrna Expression In Newly Diagnosed Multiple Myeloma Reveals A Linc01432-Celf2 Axis As An Inhibitor Of Apoptosis, Richa Mishra, Prasanth Thunuguntla, Dhanusha Duraiyan, Alani Perkin, Katelyn Bagwill, Savannah Gonzales, Catheryn Sizemore, Vanessa Brizuela, Jaiyana King, Stephen Daly, Yoon Jae Chang, Mahdote Abebe, Yash Rajana, Kelly Wichmann, Christ Enyan, Shruthi Rangineni, Mark Fiala, Julie Fortier, Reyka Jayasinghe, Mark Schroeder, Li Ding, Ravi Vij, John Dipersio, Jessica Silva-Fisher

2020-Current year OA Pubs

Multiple myeloma (MM) is an incurable malignancy of plasma cells, with over 35,000 new cases diagnosed annually in the United States. Despite an expanding arsenal of approved therapies, nearly all patients relapse, and mechanisms underlying disease progression remain poorly understood. In particular, the role of long non-coding RNAs (lncRNAs) in MM progression and treatment response is largely unexplored. To address this gap, we performed transcriptome sequencing of newly diagnosed MM (NDMM) patient samples and compared individuals with short progression-free survival (PFS; < 24 months) to those with prolonged PFS (>24 months) following standard first-line therapy. We identified 157 lncRNAs upregulated in patients with short PFS, and prioritized the …

Isothermal Sloshing In A Circular Tank (Ccp-Wsi Test Case 017 Dataset), Scott Brown, Stuart Colville, Yeaw Chu Lee, Deborah Greaves

Faculty of Science and Engineering Datasets

Physical modelling dataset used for CCP-WSI Blind Test Series 5. The description is available on the CCP-WSI catalogue under "Test Case ID 017": https://ccp-wsi.ac.uk/catalogue/test_cases/test_case_017

Atg Conjugation-Dependent/Independent Mechanisms Underlie Lysosomal Stress-Induced Tfeb Regulation, Shiori Akayama, Takayuki Shima, Tatsuya Kaminishi, Mengying Cui, Jlenia Monfregola, Kohei Nishino, Andrea Ballabio, Hidetaka Kosako, Tamotsu Yoshimori, Shuhei Nakamura

Duncan NRI Faculty and Staff Publications

TFEB, a master regulator of autophagy and lysosomal biogenesis, is activated by several cellular stresses including lysosomal damage, but its underlying mechanism is unclear. TFEB activation during lysosomal damage depends on the ATG conjugation system, which mediates lipidation of ATG8 proteins. Here, we newly identify ATG conjugation-independent TFEB regulation that precedes ATG conjugation-dependent regulation, designated Modes I and II, respectively. We reveal unique regulators of TFEB in each mode: APEX1 in Mode I and CCT7 and/or TRIP6 in Mode II. APEX1 interacts with TFEB independently of the ATG conjugation system, and is required for TFEB stability, while both CCT7 and …

The George-Anne Daily, Georgia Southern University

George-Anne Media Group: Newsletters & Magazines

No abstract provided.

Inflammation And Mutational Burden Differentially Associated With Nivolumab Or Ipilimumab Combination Efficacy In Colorectal Cancer, Ming Lei, Michael J Overman, Jin Yao, Thierry André, Sara Lonardi, Heinz-Josef Lenz, Massimo Aglietta, Fabio Gelsomino, Ray Mcdermott, Ka Yeung Mark Wong, Michael A Morse, Eric Van Cutsem, Alain Hendlisz, Dana B Cardin, Bart Neyns, Andrew Hill, Anuradha Krishnamurthy, Franklin Chen, Samith Kochuparambil, Robert R Jenq, Sandzhar Abdullaev, Beilei He, Ruslan Novosiadly, Scott Kopetz

Faculty, Staff and Student Publications

Nivolumab alone and in combination with ipilimumab demonstrated durable clinical benefit in patients with previously treated microsatellite instability-high/mismatch repair-deficient metastatic colorectal cancer in the phase 2 CheckMate 142 study. Here, we report exploratory biomarker analyses from CheckMate 142 evaluating associations between various tissue biomarkers and the efficacy of nivolumab monotherapy and nivolumab plus ipilimumab combination in these patients. Higher expression of inflammation-related gene expression signatures is associated with improved response per investigator assessment and survival benefit with nivolumab monotherapy. In contrast, higher tumor mutational burden, tumor indel burden, and degrees of microsatellite instability are associated with improved response per investigator …

Quantitative Proteomics Identifies Conserved Proteins And Altered Regulation Of Mucin-16 In Low Grade Serous Ovarian Cancers, Christopher M Tarney, Paulette Mhawech-Fauceglia, Jonathan D Ogata, Julie Oliver, Tamara Abulez, Philip A Branton, Saeid Movahedi-Lankarani, Brian L Hood, Kelly A Conrads, Kendal Rosalik, Kwong-Kwok Wong, David M Gershenson, Sanghoon Lee, Anil K Sood, Robert C Bast, Kathleen M Darcy, Neil T Phippen, G Larry Maxwell, Thomas P Conrads, Nicholas W Bateman

Faculty, Staff and Student Publications

BACKGROUND: Low-grade serous ovarian carcinoma (LGSOC) is a rare and largely chemoresistant subtype of epithelial ovarian cancer. Unlike treatment for high-grade serous ovarian cancer (HGSOC), management options for LGSOC patients are limited, in part, due to a lack of deep molecular characterization of this disease. To address this limitation, we aimed to define highly conserved proteome alterations in LGSOC by performing deep quantitative proteomic analysis of tumors collected from LGSOC and HGSOC patients or normal fallopian tube tissues and validating proteins within two independent proteomic datasets of LGSOC and HGSOC tumors.

METHODS: Formalin-fixed, paraffin-embedded LGSOC (n = 12), HGSOC (n …

Atg16l1 Controls Mammalian Vacuolar Proton Atpase, Thabata L A Duque, Masroor Paddar, Einar Trosdal, Ruheena Javed, Lee Allers, Michal H Mudd, Prithvi Akepati, Soumya R Mishra, Michelle Salemi, Brett Phinney, Shawn B Bratton, Thomas Wileman, Vojo Deretic

Faculty, Staff and Student Publications

The mechanisms governing mammalian proton pump V-ATPase function are of fundamental and medical interest. The assembly and disassembly of cytoplasmic V1 domain with the membrane-embedded V0 domain of V-ATPase is a key aspect of V-ATPase localization and function. Here, we show that the mammalian protein ATG16L1, primarily appreciated for its role in canonical autophagy and in noncanonical membrane atg8ylation processes, controls V-ATPase. ATG16L1 knockout elevated V-ATPase activity, increased V1 presence on endomembranes, and increased the number of acidified intracellular compartments. ATG16L1's ability to efficiently bind V-ATPase was required for its inhibitory role in endolysosomal acidification and for control of Mycobacterium …

Assessing A Community Health Worker-Facilitated, Digitally Delivered, Family-Centered Diabetes Management Program: Single-Arm Quasi-Experimental Study, Zenong Yin, Vanessa L Errisuriz, Heather Cuevas, Bertha E Flores, Laura Delfausse, Christina Galvan, Jing Wang, Chengdong Li, Renata Morfin, Shiyu Li, Maysa Sapargeldiyeva, Giliane Yza Muyna, Minyu Zhang, Vanessa Sweet, Deborah Parra-Medina

Faculty, Staff and Student Publications

Background: The high prevalence of type 2 diabetes (T2D) and associated complications disproportionately affect low-income Latino populations, who also experience disparities in diabetes self-management (DSM), including poor medication adherence, physical activity, diet, and glycemic control.

Objective: This study examined, through an academic-community partnership, the effectiveness of ¡Salud, Salud! (an evidence-based, family-centered diabetes self-management education and support [DSMES] program) on primary (glycemic control and quality of life) and secondary (social, psychological, and behavioral factors related to T2D management) outcomes among low-income Latino adults with T2D or prediabetes.

Methods: In total, 81 adults (mean age 48.90 years, SD 12.57; n=57, 70.4%, female; …

Squamous Non-Small Cell Lung Cancer: Current And Emerging Treatment Options, Paul K Paik, Jianjun Zhang, Howard Jack West, Jonathan W Riess

Faculty, Staff and Student Publications

Although the pharmacologic management of non-small cell lung cancer (NSCLC) has advanced substantially in the past 2 decades, disparities in the applicability to different histologic subtypes remain. Several treatment options are not suitable for squamous NSCLC, with use restricted to nonsquamous NSCLC (eg, bevacizumab and pemetrexed) because of safety concerns or comparative activity. Differences in mutational landscapes and a lack of matched targeted therapies specific to squamous NSCLC oncogenic aberrations present additional limitations. In the absence of suitable targeted therapies, immunotherapy with or without chemotherapy is the mainstay of squamous NSCLC treatment; however, survival-related outcomes remain poorer for patients with …

Westminster Apts. Llc V. Deetjen

All Decisions

In this nuisance/breach of lease holdover proceeding, the tenant moved to dismiss, arguing the landlord's petition was defective for failure to serve a 30-day termination notice under the federal CARES Act, as the property had a federally backed mortgage. The court denied the motion, holding that the CARES Act's 30-day notice requirement applies exclusively to non-payment proceedings, not to holdover proceedings based on nuisance or lease breach. The court found that subsections (b) and (c) of 15 U.S.C. § 9058 must be read in unison, and the notice provision (c) is implicitly limited by subsection (b)'s express reference to non-payment …

Lenox Twins Llc V. Watson

All Decisions

In this rent-stabilized nuisance holdover proceeding, the tenant moved for summary judgment to dismiss the petition, while the landlord cross-moved to amend the petition. The court found the landlord's predicate notice sufficiently detailed the alleged nuisance conduct. However, the tenant presented a sworn affirmation flatly denying the nuisance allegations, including throwing garbage from windows. The landlord failed to offer any rebuttal from an individual with personal knowledge or competent corroborating evidence. Consequently, the court granted the tenant's motion for summary judgment, dismissing the petition, and denied the landlord's cross-motion as moot.

Phytochemisty And Antioxidant Activity Of Ethanol, Ethyl Acetate, And N-Hexane Extracts Of Suruhan Leaves (Peperomia Pellucida), Ade Arsianti, Steven Gill, Diyah Kristanty

Indonesian Journal of Medical Chemistry and Bioinformatics

Background: Free radicals are natural byproducts of cellular metabolism, in which, their excessive accumulation can lead to oxidative stress, which plays a key role in the development of various chronic diseases, including cancer, cardiovascular disorders, and neurodegenerative conditions. Antioxidants are compounds capable of scavenging free radicals and minimizing oxidative damage. Peperomia pellucida, commonly known as Suruhan leaves, is a tropical herb traditionally used in folk medicine that contain bioactive compounds correlated with a strong radical-scavenging activity, suggesting its potential as a natural antioxidant source. This study aims to conduct a phytochemical analysis and evaluate the antioxidant activity of ethanol, …

Retrospective, Single-Center Assessment Of A Pharmacist-Led Anti-Methicillin-Resistant Staphylococcus Aureus (Mrsa) Therapy Bundle To Enhance Antimicrobial Stewardship, Jeyma Fernandez, Alice Margulis Landayan, Jorge Murillo, Stephen Breazeale, Timothy Gauthier

All Publications

No abstract provided.

Follow Me Into Math: Near-Peer Influencers Take The Stage, Aaron T. Wilson, Sergey Grigorian, Mayra Ortiz Galarza, Xiaohui Wang

School of Mathematical & Statistical Sciences Faculty Publications

Young people like to be entertained, and to entertain others. What if students were to invest enough of their time and effort into learning topics from our mathematics courses to become experts in the eyes of their peers? In this study we positioned college students and high school students as mathematical performers on the stage in front of their nearpeers, for whom they became math influencers, developing and presenting MathShows. The paper shows readers how we positioned students on the stage, using a 7-step MathShow Design Process informed by a Neer-peer Mathematical Mentoring framework. Of import for educators, researchers and …

Proceedings Of The Tolkien 2019 Conference (2025), Edited By Will Sherwood, Ross Smith

Journal of Tolkien Research

Book review, by Ross Smith, of Proceedings of the Tolkien 2019 Conference (2025), edited by Will Sherwood.

The Taxonomy And Origins Of Folia: A Brief Review, Donald G. Davis, Louise D. Hose, Harvey R. Duchene

International Journal of Speleology

All folia demonstrate a few common elements: folia (singular, folium) are planar or sub-planar speleothems, slanting downward and away from cave walls and ceilings, and genetically associated with fluctuating environmental interfaces. They were first identified and named from examples in western USA hypogenic caves but have since been identified elsewhere in the world. Folia shelves are typically composed of calcite and interweave smoothly along sub-horizontal contours. Calcite accretion, both chemical and mechanical from suspended particles, follows water-surface fluctuations to form protrusions in arrays along walls and ceilings where new accretion tends to follow the water-surface downward during descending phases, gradually …

The Assessment Of Prosodic Writing Skills Among The Students Of The Arabic Language Bachelor Program In The Light Of The Variables Of Gender And Cumulative Average At King Khalid University, Fatimah Shaaban Asiri

University of Bisha Journal for Educational Sciences

The research aimed to identify the level of prosodic writing skills among the students of the Arabic language bachelor program. To achieve the objectives of the research, the descriptive approach was used. The researcher prepared a prosodic writing skills test. The research sample consisted of (187) male and female undergraduate students in the Arabic language major, males and females, at King Khalid University in its various branches. The results resulted in a list of (10) prosodic writing skills. The results showed that the percentage of mastery of students of the Arabic language program at King Khalid University in prosody writing …

A Proposed Training Program For Developing Reciprocal Teaching Skills For Secondary School English Language, Ahmad Atif Alshehri, Ahmed Awad Asiri

University of Bisha Journal for Educational Sciences

This research aims to prepare a proposed training program for devel-oping reciprocal teaching skills for secondary school English language teachers. To achieve this goal, the researcher prepared a list of recip-rocal teaching skills. In the light of this،, a questionnaire was prepared to identify the training needs of English language teachers at second-ary school and their level of the 315 English language teachers in the secondary school which affiliate to the department of education in Asseer Region. The researcher used the descriptive approach in pre-paring the research tool. The results of research resulted in a list of training needs in …

Level Of The Teaching Practices Promoting Collective Mathematical Argumentation In The Intermediate Stage Mathematics Classrooms, Ibrahim Alhussain Khalil

University of Bisha Journal for Educational Sciences

This study aimed to evaluate the teaching practices that promote collective mathematical argumentation in middle school mathematics classrooms. It adopted the descriptive method. The sample consisted of 24 teachers of mathematics in the middle-school stage in the Middle Education Office of the Bisha Education Directorate. Quantitative observation was used as a data collection tool, which consisted of 26 teaching practices divided into four categories. The study reached several results the most notable of which is that the level of teaching practices that promote mathematical argumentation in general amounted to (2.75 - 4.00) at an average level, in the following order: …

A Suggested Conception Of A Training Program Based On Mathematical Prowess Skills For Primary School Mathematics Teachers, Mohammed Barjas Alshahrani

University of Bisha Journal for Educational Sciences

The current research aims to build a proposed training program for the development of mathematical dexterity skills for primary school mathematics teachers, and to achieve the research objectives, a list of indicators was prepared to achieve the appropriate mathematical dexterity skills for the primary stage, which amounted to (15) indicators distributed over the five mathematical dexterity skills, and through the application of the search tool on Primary school teachers, where the sample amounted to 35 teachers, it was found that there is a great need for these needs, and in light of this, the proposed training program was prepared, and …

Teachers' Conceptions Of Mathematics Fluency And Teaching Practices That Support Creativity And Their Relationship To Teaching Efficiency, Metab Zazoo Al-Enezi

University of Bisha Journal for Educational Sciences

The study aimed to identify the correlation between mathematics teachers’ concepts of fluency in mathematics(MTCF) and teaching efficiency, as well as their teaching practices that support creativity(TPSC) and teaching efficiency, and whether gender (male-female) is a moderator variable in this relationship. The study sample consisted of (170) teachers divided into (103) male and (67) female. The results of the study concluded that there is a weak, positive, and significant correlation between teachers’ concepts of fluency in mathematics and their teaching efficiency, as well as a medium, positive, and significant correlation between teaching practices that support creativity and their teaching efficiency, …

A Proposed Program In Earth And Space Based On The Next Generation Science Standards (Ngss) To Develop Some Habits Of Mind For Kindergarten Children, Mona Hashim Alzahrani

University of Bisha Journal for Educational Sciences

The study aimed to prepare a list of (NGSS) standards that must be available in the content of the kindergarten curriculum, with determining the level of inclusion of the three dimensions of the (NGSS) standards in the content of kindergarten curricula, and to develop some habits of reasoning and performance skills among kindergarten students, and the descriptive approach was used. And the experimental approach to achieve the study through application on consisting of 15 children in the kindergarten stage, whose ages range from (4-6) years. The dimensions and sum of the performance skills test and the dimensions and sum of …

Functional Competencies Of Academic Leaders In Saudi Universities In The Light Of The Objectives Of The Human Capacity Development Program (A Proposed Program), Mohammed Ahmed Ali Al Musallat, Muhammad Ahmad Huwaihi

University of Bisha Journal for Educational Sciences

The research aimed to present a proposed program for developing the functional competencies of academic leaders in Saudi universities in light of Human Capacity Development Program objectives. It used the descriptive survey method and a questionnaire consisting of (38) items distributed over (leadership competencies - technical competencies - behavioral competencies), applied to a sample of (444) faculty members (King Khalid, King Abdul-Aziz, King Saud, Imam Abd al-Rahman al-Faisal and Tabuk(.The research concluded that the sample agreed on the importance of the proposed functional competencies, provided a list of functional competencies, no statistically significant differences between the sample members regarding the …