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Articles 127591 - 127620 of 5156606
Full-Text Articles in Entire DC Network
Brewed Connections: Bringing Early Career Librarians Together Through Virtual Coffee Chats, Brandon Kennedy, Brianna Hales, Samantha Nunn, Sarah Villere, Alex Henigman
Brewed Connections: Bringing Early Career Librarians Together Through Virtual Coffee Chats, Brandon Kennedy, Brianna Hales, Samantha Nunn, Sarah Villere, Alex Henigman
Library Staff Publications
Early Career Librarians (ECLs) thrive on collaboration, informal exchange, and community elements that have been challenged by remote and hybrid work. In response, an ECL task force developed and implemented a monthly Virtual Coffee Chat project aimed at fostering informal nationwide connections among ECLs and Library and Information Science (LIS) students interested or involved in health sciences. Hosts provided discussion prompts while also fostering an open forum to discuss challenges and current events such as: AI, systematic reviews, faculty conversations, organizational structures, and training challenges. This poster presents the design, launch, and impact of the ongoing Virtual Coffee Chat project. …
Research And Application Progress Of Rap Plant-Mixed Hot Recycling Based On Oil-Stone Separation, Yu Xin, Gao Yuchao, Zhou Jie
Research And Application Progress Of Rap Plant-Mixed Hot Recycling Based On Oil-Stone Separation, Yu Xin, Gao Yuchao, Zhou Jie
Journal of China & Foreign Highway
Driven by global sustainable development strategies, China, as a major infrastructure nation, faces multiple pressures from resource constraints, environmental challenges, and its dual carbon goals. The efficient recycling of recycled asphalt pavement (RAP) has become a core issue for the green development of road engineering. Traditional recycling technologies struggle to overcome the 30% blending bottleneck due to issues such as high RAP agglomeration rates and significant gradation variability. Oil-stone separation technology deconstructs RAP to a near-virgin state through physical crushing, offering a novel pathway for high-ratio (≥30%) and even ultra-high-ratio (≥50%) RAP recycling. This paper critically reviewed systematic research on …
Mesoscopic Simulation Stu Dy On Fatigue Performance Of Asphalt Mixture Based On Discrete Element Method, Mao Quan, Zheng Junqiu, Ma Hui, Wang Min
Mesoscopic Simulation Stu Dy On Fatigue Performance Of Asphalt Mixture Based On Discrete Element Method, Mao Quan, Zheng Junqiu, Ma Hui, Wang Min
Journal of China & Foreign Highway
Asphalt pavement is prone to fatigue cracking during long-term service, which can lead to secondary diseases and weaken the structural durability. For in-depth revelation of the fatigue damage behavior of asphalt mixtures, in this paper, a semi-circular bending (SCB) mesoscopic model was established based on the discrete element method. The fatigue fracture behavior of three typical asphalt mixtures in Jiangsu Province's expressways, including SMA-13, SUP-20, and SUP-25, was simulated under different stress ratio conditions. The fatigue damage mechanism and evolution law of asphalt mixtures were analyzed from the aspects of fatigue life, crack propagation, and residual strength. The results show …
Evaluation Index Of Pavement Structural Cracks Based On Deflection Response, Zheng Junqiu, Ma Hui, Qiao Yuelai, Xu Ya, Zhou Jie, Xu Huan, Zhu Haoran
Evaluation Index Of Pavement Structural Cracks Based On Deflection Response, Zheng Junqiu, Ma Hui, Qiao Yuelai, Xu Ya, Zhou Jie, Xu Huan, Zhu Haoran
Journal of China & Foreign Highway
To accurately assess the impact of structural cracks on the strength of pavement structures and establish corresponding evaluation indicators based on deflection response, field tests were conducted on multiple sections of expressways in Jiangsu Province. A falling weight deflectometer was used to test a total of 15 measurement points within a 3-meter range on both sides of each crack. The center deflection values at each measurement point were plotted into curves, and three evaluation indicators for cracks, namely deflection range, maximum influence distance on one side of the crack, and influence area, were proposed based on the characteristics of the …
Quantification Of Activation Degree Of Aged Asphalt In Rap Fines Based On Recycled Mortar, Li Ning, Wang Ao, Tang Run, Li Jing, Li Jin
Quantification Of Activation Degree Of Aged Asphalt In Rap Fines Based On Recycled Mortar, Li Ning, Wang Ao, Tang Run, Li Jing, Li Jin
Journal of China & Foreign Highway
The oil-rich RAP fine material has a high proportion and significant asphalt content, offering considerable utilization value. However, in conventional production processes, it faces challenges such as difficult heating and insufficient activation of aged asphalt. To achieve deep regeneration, this study adopted the method of preparing recycled asphalt mortar to regenerate asphalt mixtures. However, there is currently a lack of quantitative evaluation methods for the activation degree of aged asphalt in this mortar regeneration process. Therefore, it is essential to establish an activation degree evaluation index to optimize the mortar preparation process parameters. The paper calibrated recycled asphalt mortar samples …
Evaluation Indicators Of L Ayer-Specific Structural Strength For Asphalt Pavement Based On Tsd Deflection Slope Parameters, Chen Jun, Yin Long, Ren Zhongshan, Mei W Enjie, Zhai Rui, Zhu Haoran
Evaluation Indicators Of L Ayer-Specific Structural Strength For Asphalt Pavement Based On Tsd Deflection Slope Parameters, Chen Jun, Yin Long, Ren Zhongshan, Mei W Enjie, Zhai Rui, Zhu Haoran
Journal of China & Foreign Highway
Traffic speed deflectometer (TSD) has been widely used in pavement maintenance, yet an indicator system for identifying layer-specific structural strength remains lacking. On the basis of a three-dimensional finite element model incorporating viscoelastic damage, this study analyzed how surface damage density and the modulus of the base and subbase affect deflection slope. Two layer-sensitive indicators of structural strength were proposed:S10 (deflection slope 10 cm ahead of the load center) for characterizing the surface layer, and S30 (deflection slope 30 cm ahead of the load center) for reflecting the structural strength of the base layer. Simulation results show that S10 is …
Influence Of Reflective Cracks On The Mesoscopic Mechanical Behavior Of Asphalt Pavement Structures, Ma Hui, Ren Zhongshan, Wang Min
Influence Of Reflective Cracks On The Mesoscopic Mechanical Behavior Of Asphalt Pavement Structures, Ma Hui, Ren Zhongshan, Wang Min
Journal of China & Foreign Highway
To gain an in-depth understanding of the mechanical behavior of existing asphalt pavement structures affected by reflective cracks, a macro-meso coupled model of a typical semi-rigid base asphalt pavement was established based on a continuum-discrete coupling method. By incorporating reflective cracks with varying vertical lengths, the stress transfer paths, mesoscopic particle stress states, and displacement evolution of the pavement structure were analyzed. The results indicate that the coarse aggregate skeleton and the surrounding mortar collectively bear more than 75% of the traffic load, forming a critical load transfer system, and that a significant linear correlation exists between the vertical stress …
Performance Of High-Elastic Modified Asphalt For Paving-Type Recycled Stress Absorption Layer, Li Jing, Liu Linlin, Zhu Qiyang, Li Ning, Li Long
Performance Of High-Elastic Modified Asphalt For Paving-Type Recycled Stress Absorption Layer, Li Jing, Liu Linlin, Zhu Qiyang, Li Ning, Li Long
Journal of China & Foreign Highway
To enhance the performance of recycled high-elastic modified asphalt binder and achieve high-quality and high-content utilization of RAP fine materials in the design of stress absorbing layers, a highly permeable recycled high-elastic modified asphalt (ZGT-R) was prepared by adding SBS modifier, light component oil, and penetrant to replenish the degraded SBS molecules and reduce intermolecular forces. The conventional properties, elastic recovery, degree of fusion between new and aged asphalt, rheological properties, and micro-modification mechanism of ZGT-R and ordinary recycled high-elastic modified asphalt before and after the addition of the rejuvenator were analyzed. The results show that, compared with the two …
Crack Propagation Behavior Of Polyurethane Grouting Sma Asphalt Mixtures, Ji Guoqi, Ma Hui, Zheng Junqiu, Huang Yujie
Crack Propagation Behavior Of Polyurethane Grouting Sma Asphalt Mixtures, Ji Guoqi, Ma Hui, Zheng Junqiu, Huang Yujie
Journal of China & Foreign Highway
To reveal the influence me chanis m of polyurethane grouting on the crack propagation behavior of SMA-13 asphalt mixtures, this paper first conducted a semi-circular bending (SCB) test to validate the effectiveness of the PFC2D discrete element model, which was employed to simulate the microscopic responses of mixtures under different notch positions and grouting conditions. The analysis focused on load-displacement curves, crack propagation paths, crack number evolution, and force chain distribution characteristics. The results indicate that polyurethane grouting significantly increases the peak load and peak displacement of the specimens, thereby enhancing the fracture load-bearing capacity and deformation tolerance, with the …
Workability And Improvement Evaluation Of Warm-Mixed High-Content, Sbs Asphalt Mixturesguo Yongjia, Jin Yong, Luo Chufan, Zhou Yusong, Zu Yuanzhe, Deng Xinyi, Song Yuhang
Workability And Improvement Evaluation Of Warm-Mixed High-Content, Sbs Asphalt Mixturesguo Yongjia, Jin Yong, Luo Chufan, Zhou Yusong, Zu Yuanzhe, Deng Xinyi, Song Yuhang
Journal of China & Foreign Highway
High-content SBS-modified asphalt has been widely used in high-grade highway pavement engineering due to its excellent mechanical properties and adaptability to heavy traffic. However, its application is hindered by high energy consumption and poor workability at elevated temperatures, which limits the development of green and efficient construction practices. In this study, on the basis of warm mix technology, a self-developed organic viscosi ty-reducing warm-mixed additive was incorporated to establish a warm-mixed asphalt mixture system with high-content SBS modification. With SMA-13 as the target gradation, the mixing and compaction workability was evaluated. A self-developed apparatus for mixing workability testing was used …
Rheology And Microstructure Of Warm-Mixed High-Content Sbs Modified Asphalt, Wan Lei, Dong Fuqiang, Chen Jinzhen, Chen Jiaqiang, Song Yuhang, He Haonan
Rheology And Microstructure Of Warm-Mixed High-Content Sbs Modified Asphalt, Wan Lei, Dong Fuqiang, Chen Jinzhen, Chen Jiaqiang, Song Yuhang, He Haonan
Journal of China & Foreign Highway
With the gradual shift of high-grade highways in China from construction to maintenance, higher performance requirements have been placed on asphalt binders. High-content SBS modified asphalt has become an inevitable choice for both new pavement construction and maintenance. However, conventional high-content SBS modified asphalt suffers from high energy consumption, excessive carbon emissions, and poor construction workability. In this study, a self-developed warm-mixed additive was introduced into high-content SBS modified asphalt, and the process was optimized to obtain warm-mixed SBS modified asphalt. The effects of the additive on the asphalt performance and the warm-mix efficiency were evaluated in terms of viscosity-temperature …
Design And Performance Of Solvent-Based Regenerated Cold Feed For Fine Screening, Yan Chunpeng, Zhu Yaoting, Fan Xiangyang, Liu Bin, Yi Zhao
Design And Performance Of Solvent-Based Regenerated Cold Feed For Fine Screening, Yan Chunpeng, Zhu Yaoting, Fan Xiangyang, Liu Bin, Yi Zhao
Journal of China & Foreign Highway
To overcome the limitations of evaluatio n methods for the performance of cold patching asphalt mixtures, this paper systematically studied the pavement performance and its evaluation system of solvent-based cold patching asphalt mixtures using fully finely stripped and sieved reclaimed materials. Meanwhile, a multi-stage research approach was adopted to conduct an in-depth investigation. Firstly, the material ratio of the new solvent-based cold patching liquid was optimized based on the orthogonal test design method. Subsequently, an evaluation system covering key performance indicators and the corresponding technical standards was constructed. On this basis, the developed evaluation method was applied to conduct a …
Influence Of Ultra-Fine Iron Tailings Sand On Performance Of Cement-Stabilized Macadam Base, Meng Delong, Li Hongzhen, Chen Fushen, Wang Keran, Jiang Yuntao, Chen Lei, Feng Zhuangzhuang
Influence Of Ultra-Fine Iron Tailings Sand On Performance Of Cement-Stabilized Macadam Base, Meng Delong, Li Hongzhen, Chen Fushen, Wang Keran, Jiang Yuntao, Chen Lei, Feng Zhuangzhuang
Journal of China & Foreign Highway
To study the application potential of ultra-fine iron tailings sand (UITS) as a road base material, this paper conducted unconfined compressive strength (UCS) tests and freezing and thawing tests to systematically analyze the effects of UITS content and cement content on the mechanical properties and durability of cement-stabilized UITS. Additionally, the scanning electron microscope (SEM) was employed to examine the evolution process of the microstructure. The results indicate that the appropriate UITS content can effectively improve UCS, with the optimal strength under the 20% UITS content and comparable strength to that of conventional cement-stabilized macadam under the 30% content. Increasing …
Efficient Smooth Tensor Train And Tensor Ring Completion For Image Classification Enhancement, Salman Ahmadi-Asl, Roman V. Garaev, Rustam A. Lukmanov, Naeim Rezaeian, Asad Masood Khattak, Manuel Mazzara
Efficient Smooth Tensor Train And Tensor Ring Completion For Image Classification Enhancement, Salman Ahmadi-Asl, Roman V. Garaev, Rustam A. Lukmanov, Naeim Rezaeian, Asad Masood Khattak, Manuel Mazzara
All Works
This paper deals with studying the data completion problem for enhancing the image classification task under the pixel removal scenario. In some applications, it happens that a part of the pixels of a given image is lost due to several issues, such as corruption by outliers or artifacts and/or incompleteness due to imprecise data acquisition. This issue results in a completely wrong classification outcome using Deep Neural Networks (DNNs). In this paper we investigate the benefit of data completion in enhancing the classification accuracy of the DNN models to build more robust and stable DNN models. To this end, we …
10.27.2025 Ored Connect, Liz Williamson
10.27.2025 Ored Connect, Liz Williamson
ORED Newsletter
ORED Field Fest
OTC Director Candidates
Librarians On-Call: A Review Of Search Tools Utilized By Fourth Year Medical Students On A Mock Call, Celeste Perez, Brandon Kennedy, Katie Prentice, Sonya Fogg, Jennifer Stockton, Bronwyn Sutherland, Lara Oulette, Sandra Desjardins, Beatriz Varman, Tracy Ashby
Librarians On-Call: A Review Of Search Tools Utilized By Fourth Year Medical Students On A Mock Call, Celeste Perez, Brandon Kennedy, Katie Prentice, Sonya Fogg, Jennifer Stockton, Bronwyn Sutherland, Lara Oulette, Sandra Desjardins, Beatriz Varman, Tracy Ashby
Library Staff Publications
OBJECTIVE: A team of medical librarians were given the opportunity to observe the medical readiness of fourth year medical students (MS4s) for finding evidence-based clinically relevant information (drug choice, patient care, etc.) during an on-call simulation. For this initial analysis, we observed the search tools utilized by MS4s when asked to recommend treatment for simulated patients.
METHODS: 10 librarians were asked to evaluate 1 module of a simulation required of 240 MS4s as a gauge of their readiness to be residents on call. A Night On-Call Simulation program was used to record their responses & online navigation. The MS4s attended …
Student Life E-Newsletter October 27, 2025, Seattle University School Of Law Student Life
Student Life E-Newsletter October 27, 2025, Seattle University School Of Law Student Life
Student Life E-Newsletters
No abstract provided.
Fostering Sustainability Literacy And Action Through Language Education: Perspectives And Practices Across Regions, Maria-José De La Fuente, Odette Gabaudan, Kiley Kost, Owain Llewellyn, Pilar Molina, Seth Peabody
Fostering Sustainability Literacy And Action Through Language Education: Perspectives And Practices Across Regions, Maria-José De La Fuente, Odette Gabaudan, Kiley Kost, Owain Llewellyn, Pilar Molina, Seth Peabody
Research Outputs: 2025-Present
This activity report explores the integration of Education for Sustainable Development (ESD) in language pedagogy, focusing on its potential to equip students with both linguistic proficiency and the competencies needed to address complex global challenges. Rooted in the context of TU (Technical University) Dublin’s commitment to embedding sustainability in Higher Education curricula, the activity report builds on insights from a 2023 roundtable discussion convened by two of the authors in collaboration with CercleS and the United Nations Institute for Training and Research (UNITAR) on the occasion of its first Research conference. Featuring perspectives from scholars in sustainability and language education, …
The Echo: October 27, 2025, Taylor University
The Echo: October 27, 2025, Taylor University
2025-2026 (Volume 113)
No abstract provided.
Validation Of A Prognostic Nomogram For Locally Advanced Oropharyngeal Carcinoma Treated With Intensity-Modulated Radiotherapy With/Without Systemic Therapy, P. Bossi, R. Gili, S. Calza, L. Licitra, M. Maddalo, A. Bacigalupo, L. Belgioia, J. Cacicedo, N. Facchinetti, A. Garcia Castano, M. Oliva, P. Bonomo, G. Sanguineti, P. Franco, A. Argiris, A. Psyrri, E. Orlandi
Validation Of A Prognostic Nomogram For Locally Advanced Oropharyngeal Carcinoma Treated With Intensity-Modulated Radiotherapy With/Without Systemic Therapy, P. Bossi, R. Gili, S. Calza, L. Licitra, M. Maddalo, A. Bacigalupo, L. Belgioia, J. Cacicedo, N. Facchinetti, A. Garcia Castano, M. Oliva, P. Bonomo, G. Sanguineti, P. Franco, A. Argiris, A. Psyrri, E. Orlandi
Kimmel Cancer Center Faculty Papers
BACKGROUND: Head and neck squamous-cell carcinoma (HNSCC), particularly oropharyngeal cancer (OPC), exhibits diverse prognostic factors influenced by demographic and lifestyle variables. Prognostic nomograms, such as the one developed by Fakhry et al., incorporate clinical and biological markers to predict overall survival (OS) and progression-free survival (PFS) in OPC patients. However, their applicability to European populations remains unverified. This study aimed to externally validate Fakhry's prognostic nomogram in a large European cohort of locally advanced OPC patients treated with definitive intensity-modulated radiotherapy (IMRT) with or without systemic therapy.
METHODS: This is a retrospective external validation study conducted on 805 OPC patients …
Surface Chemistry-Dependent Binding Interactions Between Kraft Lignin And Polyelectrolyte-Encapsulated Gold Nanoparticles, Oluwaseun Ayodeji Akinsola, Samuel Lohse
Surface Chemistry-Dependent Binding Interactions Between Kraft Lignin And Polyelectrolyte-Encapsulated Gold Nanoparticles, Oluwaseun Ayodeji Akinsola, Samuel Lohse
All Faculty Scholarship for the College of the Sciences
This study investigated the relationship between gold nanoparticle (AuNP) surface chemistry and the binding affinity of unfractionated kraft lignin to polyelectrolyte-coated AuNPs. Specifically, fluorescence quenching titrations were employed to determine lignin’s binding affinity (Ka) to different charged polymer surfaces displayed on 90 nm citrate-stabilized AuNPs, (poly(allylamine hydrochloride)) (PAH), polyacrylate (PAA), and poly(diallyldimethylammonium chloride) (PDADMAC). AuNP–lignin conjugates were characterized by UV–vis absorbance spectroscopy, ζ-potential analysis, and dynamic light scattering (DLS) measurements. The characterization data showed that the size, surface charge and aggregation state of the lignin–AuNP conjugates depended on the original surface chemistry of the AuNP, in conjunction …
Research On Enhancement Of Toughness Performance In Polyurethane-Modified Epoxy Asphalt, Liang Bo, Liao Xintao, Liao Wei, Jiang Hui, Qin Ruiming
Research On Enhancement Of Toughness Performance In Polyurethane-Modified Epoxy Asphalt, Liang Bo, Liao Xintao, Liao Wei, Jiang Hui, Qin Ruiming
Journal of China & Foreign Highway
To solve low toughness and high brittleness of epoxy asphalt under low-temperature conditions, in this study, polyether-type polyurethane (JMPU) and polyester-type polyurethane (JZPU) were employed to prepare modified epoxy asphalt. Firstly, the Brookfield viscosity test, infrared spectroscopy test, and fluorescence microscopy were utilized to characterize the curing process. The curing time and curing temperature of JMPU and JZPU modified epoxy asphalt were 3 h/140°C and 4 h/150°C, respectively. With styrene-butadiene-styrene block copolymer (SBS), a common modifier, as the control, the performance changes of epoxy asphalt before and after modification with different toughening agents were evaluated through mechanical tensile test, rheological …
Research On Fatigue Damage And Crack Propagation Of Pre-Cut Seam Asphalt Mixture Composite Beams, Huang Dengke, Liu Hongfu
Research On Fatigue Damage And Crack Propagation Of Pre-Cut Seam Asphalt Mixture Composite Beams, Huang Dengke, Liu Hongfu
Journal of China & Foreign Highway
This study investigated the influence of reflective cracking on the fatigue performance of asphalt pavements subjected to milling and resurfacing under varying service conditions. The fatigue life of composite beams was evaluated via four-point bending fatigue tests, considering the effects of different stress ratios, soaking durations, air void contents, and types of tack coat. Meanwhile, the digital image correlation (DIC) technique was employed to analyze the crack propagation behavior of composite beams. To accurately characterize the failure of composite beam specimens, the dynamic modulus was employed to define damage variables, enabling the calculation of critical fatigue damage for the composite …
Preparation And Road Performance Of Cold Patching Materials Modified By Polyurethane Prepolymer, Yang Wei, Zhai Xueguo, Guo Weixiong, Chi Haozhan
Preparation And Road Performance Of Cold Patching Materials Modified By Polyurethane Prepolymer, Yang Wei, Zhai Xueguo, Guo Weixiong, Chi Haozhan
Journal of China & Foreign Highway
Traditional cold asphalt mixtures present challenges such as inapplicability in humid environments and poor durability when used for repairing potholes in asphalt pavements. To address these issues, with polyurethane prepolymer (PUA), 70# base asphalt, and additives as raw materials, a cold patch asphalt base liquid with optimal comprehensive performance was developed using the simplex design and the ideal point method. Cold patching asphalt mixtures were also prepared, with pavement performance systematically evaluated. It indicates that the PUA content has the greatest influence on the low-temperature performance and tensile strength of the cold patching asphalt liquid. The effects of components on …
The Future Of Nonprofit Regulation In The United States: Three Dynamic Trends, Lloyd H. Mayer
The Future Of Nonprofit Regulation In The United States: Three Dynamic Trends, Lloyd H. Mayer
Journal Articles
Nonprofit regulation in the United States is strongly influenced by society-wide political trends. This influence is especially evident today with respect to racial justice debates, partisan political divides, and significant changes in federal tax law. This commentary explores both how these trends are already affecting nonprofit regulation and how they might affect nonprofit regulation in the near future.
Deficits In Motion And Form Perception In Infantile Nystagmus Syndrome, Mahesh Joshi, Asma Zahidi
Deficits In Motion And Form Perception In Infantile Nystagmus Syndrome, Mahesh Joshi, Asma Zahidi
School of Health Professions
Purpose: Visual deficits in infantile nystagmus syndrome (INS) could be a result of retinal blur from excessive eye movements and/or cortical changes from visual deprivation. We measured global motion and form sensitivity in INS to compare deficits between motion and form perception and to decipher the role of internal noise (local deficit such as eye movement) and sampling efficiency (global cortical deficit).Methods: A total of 30 participants (14.40 ± 4.83 years) with INS and 30 age-matched controls discriminated the direction of motion and orientation of physically equivalent translational random dot kinematograms (RDKs) and Glass patterns. Both stimuli consisted of 240 …
The Volume And Characteristics Of Research On Gastrointestinal Symptoms In ‘Natural’ Peri- And Postmenopause:: A Scoping Review, Naomi Shaw, Rebecca Abbott, Clare Pettinger
The Volume And Characteristics Of Research On Gastrointestinal Symptoms In ‘Natural’ Peri- And Postmenopause:: A Scoping Review, Naomi Shaw, Rebecca Abbott, Clare Pettinger
School of Health Professions
BACKGROUND: Menopause has been linked to an array of symptoms, often with adverse effects on quality of life, work and relationships. Despite evidence of economic and social impacts, and a growing population of menopausal individuals, there are significant gaps in knowledge regarding menopause. Gastrointestinal (GI) symptoms in peri- and postmenopause are areas of uncertainty that warrant further investigation.
OBJECTIVES: Following JBI guidance, this scoping review aimed to systematically map research on GI symptoms in 'natural' peri- and postmenopause, exploring the volume and conduct of research, and variables investigated that could influence symptom experience.
ELIGIBILITY CRITERIA: Studies assessing GI symptoms (constipation, …
Single Local Injection Of 3s-Hmgb1 Enhances Early Bone Healing And Titanium Implant Osseointegration In Type 2 Diabetic Mice, Bhuvana L. Chandrashekar, Alexandra Arteaga, Evelin Rios, Jimena Mora, Gustavo P. Garlet, Danieli Rodrigues, Cláudia Cristina Biguetti
Single Local Injection Of 3s-Hmgb1 Enhances Early Bone Healing And Titanium Implant Osseointegration In Type 2 Diabetic Mice, Bhuvana L. Chandrashekar, Alexandra Arteaga, Evelin Rios, Jimena Mora, Gustavo P. Garlet, Danieli Rodrigues, Cláudia Cristina Biguetti
School of Podiatric Medicine Publications
Diabetes significantly impairs bone healing via several mechanisms, including sustained inflammation, oxidative stress, and poor osteogenic responses. Fully reduced isoform of High Mobility Group Box 1 with three serine substitutions (3S-HMGB1) has shown regenerative properties while being resistant to oxidative degradation.
Objective: This study evaluated the therapeutic potential of a single local injection of 3S-HMGB1 in early osseointegration under diabetic conditions in mice.
Methodology: A total of 48 male 129/Sv mice (24 non-diabetic [ND], 24 diabetic [D]) received titanium implants following maxillary first molar extraction. ND and D mice (n:12) were injected with either saline (control) or 3S-HMGB1 (0.75 mg/kg) …
Ole Miss Aiche Team Heads To Nationals With Carbon Capture Cube, Jordan Karnbach
Ole Miss Aiche Team Heads To Nationals With Carbon Capture Cube, Jordan Karnbach
University of Mississippi News
OXFORD, Miss. – Barely a year after restarting a chapter of the American Institute of Chemical Engineers on campus, a University of Mississippi team of chemical engineering students is preparing to face off against some of the field's biggest programs in a national competition.