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Enhancing Grid Integration Of High-Power Loads Through Modular Unfolding-Based Power Conversion With Decentralized Control, Sanat R. Poddar Dec 2025

Enhancing Grid Integration Of High-Power Loads Through Modular Unfolding-Based Power Conversion With Decentralized Control, Sanat R. Poddar

All Graduate Theses and Dissertations, Fall 2023 to Present

The transition to electric vehicles (EVs) is a critical step toward reducing greenhouse gas emissions and creating a cleaner, more sustainable transportation sector. However, many drivers — particularly those operating larger vehicles such as trucks and buses — face significant challenges, including limited driving range and lengthy charging times. High-power, fast-charging stations, which can rapidly replenish EV batteries, are therefore essential for mitigating these barriers and making electric transportation practical across all vehicle classes.

Despite the promise of electric vehicles, deploying high-power fast-charging stations presents significant challenges. They require large amounts of electricity, making them expensive to install, operate, and …


Impacts Of Including Sprouted Barley In The Diet Of Beef Cattle On Production, Ruminal Health, And Meat Quality, Zachary C. Crump Dec 2025

Impacts Of Including Sprouted Barley In The Diet Of Beef Cattle On Production, Ruminal Health, And Meat Quality, Zachary C. Crump

All Graduate Theses and Dissertations, Fall 2023 to Present

Beef producers in the United States are working to meet rising global demand for animal protein while facing major challenges such as drought, climate uncertainty, and rapid urbanization. These issues make it difficult to produce consistent and dependable feed, pushing producers to explore new ways to grow feed using fewer natural resources. Vertical farming systems are one option that can grow sprouted cereal grains indoors throughout the year while using decreased land and water than traditional agriculture. Sprouted barley grows within six to seven days and may serve as a nutrient dense alternative feed source for cattle at several stages …


Reconstruction And Texturing Of 3d Surfaces From Fused Low-Cost Aerial Lidar And Optical Imagery, Samuel Kiguthi Dec 2025

Reconstruction And Texturing Of 3d Surfaces From Fused Low-Cost Aerial Lidar And Optical Imagery, Samuel Kiguthi

All Graduate Theses and Dissertations, Fall 2023 to Present

Drones equipped with laser scanners (LiDAR) and cameras capture detailed 3D scenes. Combining the laser points with photos builds realistic, photo-textured 3D maps used in surveying, agriculture, and infrastructure planning. Conventional methods to create these maps often misrepresent inward shapes such as doorways, overhangs, and outcrops. These shapes are misrepresented because drones mainly view top surfaces and do not collect significant data on vertical or hidden areas.

This study introduces a surface-reconstruction method that groups LiDAR points into clusters, reconstructs smooth surfaces for each cluster, and uses information from recorded camera poses to stitch clusters together. Tests on real drone …


Built For Participation: A Set Of Measures For Evaluating Community Living For People Of All Abilities As Supported By The Built Environment, Christopher A. Wilson Ii Dec 2025

Built For Participation: A Set Of Measures For Evaluating Community Living For People Of All Abilities As Supported By The Built Environment, Christopher A. Wilson Ii

All Graduate Theses and Dissertations, Fall 2023 to Present

As the world enters a new era of urban living, it is important to develop cities that allow residents of all ages and abilities to fully participate in society. Integration of people with disabilities into daily community living involves looking beyond site- or product-specific features to community- and city-wide systems. Some tools have been developed to begin evaluating cities’ levels of inclusive social participation and to provide recommendations for city planning professionals. However, the tools that have been developed often are too complex for practical use or rely on data that varies in obtainability. Therefore, the purpose of this series …


Spatial Strategies For Restoring Native Biodiversity And Connectivity In Managed Landscapes Of The Upper Clutha Basin, New Zealand, Jessica Zuban Dec 2025

Spatial Strategies For Restoring Native Biodiversity And Connectivity In Managed Landscapes Of The Upper Clutha Basin, New Zealand, Jessica Zuban

All Graduate Theses and Dissertations, Fall 2023 to Present

Across New Zealand and around the world, biodiversity is declining due to the widespread loss and fragmentation of native habitat. This is especially true in agricultural landscapes, where native habitats have been replaced by intensive land use. This research focuses on the Upper Clutha Basin in Central Otago, New Zealand that has been significantly altered over time by farming, development, and other human activities. As a result, only a small amount of native vegetation remains, and the region is well below the critical threshold needed to support healthy ecological systems.

This study investigates how native vegetation can be strategically restored …


Design, Control, And Optimization Of Unfolding-Based Ac-Dc Topologies With Three-Port Resonant Converters For Electric Vehicle Battery Charging Applications, Aditya Zade Dec 2025

Design, Control, And Optimization Of Unfolding-Based Ac-Dc Topologies With Three-Port Resonant Converters For Electric Vehicle Battery Charging Applications, Aditya Zade

All Graduate Theses and Dissertations, Fall 2023 to Present

The global effort to reduce greenhouse gas emissions and reliance on fossil fuels has made electric mobility a cornerstone of sustainable transportation. This transition is driving demand for advanced charging infrastructure and more efficient power conversion systems. Power converters play a central role, not only in enabling reliable EV charging but also in integrating renewable energy sources with the grid. Because of the large amount of power involved, these converters must operate efficiently, reliably, and at low cost. Conventional high-power chargers often use two stages of conversion, which are effective but limited by size and energy losses. To overcome these …


Material Differentiation On The Yellow Point Ridge Lithic Landscape, Gabriel Boghosian Dec 2025

Material Differentiation On The Yellow Point Ridge Lithic Landscape, Gabriel Boghosian

All Graduate Theses and Dissertations, Fall 2023 to Present

This paper identified material use differences on the Yellow Point Ridge Lithic Landscape, utilizing flake morphology to identify use stages of materials found on site. This research confirmed the viability of methods like PXRF in conjunction with Infield material identifications and geologist identifications, as well as expanded the understanding of South-west Wyoming land use by hunter-gatherers.


Biocontrol Of Canada Thistle (Cirsium Arvense) With The Rust Fungus, Puccinia Punctiformis In The Intermountain West: Integrated Weed Management Compatibility And Characterization Of Microbiome Associations, Caitlin Henderson Dec 2025

Biocontrol Of Canada Thistle (Cirsium Arvense) With The Rust Fungus, Puccinia Punctiformis In The Intermountain West: Integrated Weed Management Compatibility And Characterization Of Microbiome Associations, Caitlin Henderson

All Graduate Theses and Dissertations, Fall 2023 to Present

Canada thistle (Cirsium arvense) is an invasive weed of major concern in both agricultural and native areas. It competes against native plants, reduces crop production and quality, and causes significant costs in management and damages. Canada thistle can survive and spread through seeds, but primarily does so through its extensive root system, which causes the greatest management difficulties. There are several control methods for this invasive weed, herbicides are perhaps the most common and effective, however, they have limitations and negative consequences. Herbicide use near waterways is restricted and there are growing concerns of the development of herbicide …


Assessing The Human Health Impacts Of Nutrient-Dense Diets: Clinical Trials On Regenerative Agriculture And Protein Source, Jennifer Jensen-Cloward Dec 2025

Assessing The Human Health Impacts Of Nutrient-Dense Diets: Clinical Trials On Regenerative Agriculture And Protein Source, Jennifer Jensen-Cloward

All Graduate Theses and Dissertations, Fall 2023 to Present

Increasing consumer demand for sustainable, animal-friendly food options has sparked discussion about farming production practices. As more people prioritize their food choices, questions have circulated about how farming practices might impact not just the environment, but also human health. Regenerative agriculture is a farming method that has gained popularity for its potential to improve both food quality and environmental outcomes. It focuses on restoring ecosystem function, ultimately impacting the resulting nutrients in food products, and includes foods like grass-fed meat and organic produce. However, it is still unclear whether these practices make a difference in human health. This dissertation informs …


An Evaluation Of Virtual Reality Modeling To Improve Accuracy Of Physical Education Skills In Teenage Students With Disabilities, Kristen Lee Dec 2025

An Evaluation Of Virtual Reality Modeling To Improve Accuracy Of Physical Education Skills In Teenage Students With Disabilities, Kristen Lee

All Graduate Theses and Dissertations, Fall 2023 to Present

Virtual Reality (VR) technology is becoming more common in schools, especially for teaching and training. In this study, researchers explored how VR can help teenagers with disabilities improve their physical education skills, specifically push-ups, lunges, and jumping jacks. The participants all showed an increase in their skills and reached a high level of accuracy on every skill. The results showed that adding feedback was also necessary for some participants. Additionally, participants enjoyed using the VR equipment and showed high levels of happiness throughout the study. These findings suggested that using VR technology can be an effective way to support teenagers …


Evaluating Energy Transition Winners And Losers: Are Algae Biofuels Desirable, Feasible, And Viable?, Michelle M. Arnold Dec 2025

Evaluating Energy Transition Winners And Losers: Are Algae Biofuels Desirable, Feasible, And Viable?, Michelle M. Arnold

All Graduate Theses and Dissertations, Fall 2023 to Present

Climate change, environmental degradation, finite resources, and the uneven distribution of energy access all points to an urgent need for a global energy transition. But making that transition responsibly requires more than enthusiasm for “green” solutions—it demands careful evaluation of which energy sources are truly worth investing in. This dissertation develops a practical decision-making framework to help policymakers, scientists, and the public answer three foundational questions about any new energy technology: Is it desirable? Is it feasible? Is it viable? By systematically weighing public narratives, biophysical constraints, and patterns of innovation, the framework aims to prevent wasted time, funding, and …


Improvisation Of Mands Using Augmentative And Alternative Communication, Lauren Decker Dec 2025

Improvisation Of Mands Using Augmentative And Alternative Communication, Lauren Decker

All Graduate Theses and Dissertations, Fall 2023 to Present

Research shows that young children who use pictures to communicate can use colors, shapes, and functions of items to request when the specific picture of the item is not available. This problem-solving skill is called improvisation, which this study taught to a preschool aged participant with communication delays. A four-year-old preschool student was able to make these requests with basic colors, shapes, and three function pictures. They also were able to make these requests for items not taught to them in different settings. This suggests that improvisation training can be successfully implemented with preschool aged children with communication delays and …


Discourses Embedded In The Adams V. School Board Of St. Johns County Decision And The Rights Of Transgender Students In Schools, Douglas Larson Dec 2025

Discourses Embedded In The Adams V. School Board Of St. Johns County Decision And The Rights Of Transgender Students In Schools, Douglas Larson

All Graduate Theses and Dissertations, Fall 2023 to Present

This study was critical analysis of the language of the court case Adams v. School Board of St. Johns County (2022). This case was brough by a student against the School District challenging a policy that prevented him, a transgender boy, from using the boys’ restroom. The analysis was not intended to determine the merits of the case or the correctness of the legal reasoning. Rather, the analysis was performed on the text of the case—the language used by the judges—to learn about the beliefs, attitudes, and values of the judges.

The reason this analysis is important is because judges …


Investigating Pyrethroid Insecticide Resistance In The Alfalfa Pest Insects Hypera Postica (Alfalfa Weevil) And Lygus Spp. (Lygus Bugs) In Utah Alfalfa Fields, Rosalie Sepesy Dec 2025

Investigating Pyrethroid Insecticide Resistance In The Alfalfa Pest Insects Hypera Postica (Alfalfa Weevil) And Lygus Spp. (Lygus Bugs) In Utah Alfalfa Fields, Rosalie Sepesy

All Graduate Theses and Dissertations, Fall 2023 to Present

Chemical insecticides are commonly used to manage the damage to crops caused by agricultural pest insects. Reliance on insecticides for pest management has resulted in insecticide resistance in many insect species worldwide. Alfalfa weevils (Hypera postica) and lygus bugs (species within the genus, Lygus), are major pests to alfalfa hay and seed respectively and cause significant economic damage. The goal of this dissertation was screen Utah alfalfa fields for resistant alfalfa weevil and lygus bug populations, investigate genetic mutations that can influence resistance in alfalfa weevils, and establish which species of lygus bugs are present in Utah …


Unveiling The Interactions Between The Antibiotic Resistome And Microplastics Influenced By Trace Elements And Ppcps In Wastewater Treatment Plants, Tahira Tasneem Rahman Dec 2025

Unveiling The Interactions Between The Antibiotic Resistome And Microplastics Influenced By Trace Elements And Ppcps In Wastewater Treatment Plants, Tahira Tasneem Rahman

All Graduate Theses and Dissertations, Fall 2023 to Present

Antibiotic resistance is a growing global concern, and wastewater treatment plants play a critical role in controlling its spread. These facilities process water containing microplastics (small plastic particles), trace elements like copper and zinc, and chemicals from everyday products like pharmaceuticals and personal care products. Together, these pollutants may contribute to the survival and spread of bacteria containing antibiotic resistance genes, but their combined effects are not fully understood. This study investigated how these pollutants behave and interact in wastewater treatment plants using two approaches: direct monitoring of real treatment plants and controlled lab experiments using synthetic wastewater. Results showed …


The Effects Of Lactoferrin And Iron-Enriched Whey On Iron Status Of Collegiate Females, Connor Kemp Dec 2025

The Effects Of Lactoferrin And Iron-Enriched Whey On Iron Status Of Collegiate Females, Connor Kemp

All Graduate Theses and Dissertations, Fall 2023 to Present

Iron deficiency has remained a global issue even in developed countries despite food fortification and increased nutritional literacy, biological women of child baring age are at particular risk due to menstruation and reduced dietary intake of iron containing foods compared to men. This issue is of particular concern in athletics due to the critical role of iron in oxygen transport and energy metabolism. With nearly half of female athletes presenting low iron status iron supplementation is often necessary. With iron supplementation often resulting in gastrointestinal symptoms that could negatively impact sport performance itself there is a need to explore other …


Lace Network Firmware: A Polarfire Fpga Network For Data Routing And Command Interfacing In Space Applications, Kade C. Howes Dec 2025

Lace Network Firmware: A Polarfire Fpga Network For Data Routing And Command Interfacing In Space Applications, Kade C. Howes

All Graduate Theses and Dissertations, Fall 2023 to Present

Modern small spacecraft rely on powerful yet efficient onboard compute devices to process data from sensors in real-time due to tight power and volume constraints. This work explores a new compute device system built from PolarFire Field-Programmable Gate Arrays (FPGAs), which are power-efficient, reprogrammable chips well-suited for space applications. The system connects via a central controller FPGA with one or multiple companion processing FPGAs, allowing sensor data to be quickly received and shared across the network. Standardized data formats and interfaces increase compatibility with spacecraft computers. By simplifying data handling and using high-speed communication links, this architecture makes it easier …


Understanding Impact Of Starter Culture Blends On The Ph Variation In Cheddar Cheese During Early Aging, Samuel J. Clarke Dec 2025

Understanding Impact Of Starter Culture Blends On The Ph Variation In Cheddar Cheese During Early Aging, Samuel J. Clarke

All Graduate Theses and Dissertations, Fall 2023 to Present

Consumer expectations govern what is acceptable when it comes to the flavor, texture, and color of the cheese. These quality attributes of cheese are all influenced by the pH of the cheese which is in turn controlled by the acid production of the starter lactic acid bacteria (SLAB) used to make cheese. Whatever the final pH of the cheese is, is what determines the quality of the cheese. Unfortunately, there are some Cheddar cheese manufacturers that have observed pH variation during the early aging of their cheeses. We hypothesize that the addition of thermophilic, fast-acid producing bacteria, like Streptococcus thermophilus …


A Software Framework For Translating Onnx Models Onto The Lace-C3a Hardware, Shawn Jones Dec 2025

A Software Framework For Translating Onnx Models Onto The Lace-C3a Hardware, Shawn Jones

All Graduate Theses and Dissertations, Fall 2023 to Present

Modern computers are powerful, but they are not always efficient enough for small, low power systems like those used on satellites and scientific instruments. To solve this problem, engineers often turn to FPGAs—reconfigurable computer chips that can be customized to run specific tasks much faster and with far less energy than ordinary processors. However, finding the best possible design for an FPGA program is extremely difficult because there are millions of ways a design could be built, and only a small fraction of them actually perform well.

This thesis presents SNOW, a new framework that helps automate the search for …


The Microstructure Of Metastatic Bone Lesions Suggests Tumor Mediated Alterations In Bone Mineralization, Hanwen Fan, Zhan Xu, Carla Berrospe Rodriguez, Noah Dover, Andrei Demkov, Morgan Lilly, Guillermo Aguilar, Larry J Suva, Xiang H-F Zhang, Yuxiao Zhou Dec 2025

The Microstructure Of Metastatic Bone Lesions Suggests Tumor Mediated Alterations In Bone Mineralization, Hanwen Fan, Zhan Xu, Carla Berrospe Rodriguez, Noah Dover, Andrei Demkov, Morgan Lilly, Guillermo Aguilar, Larry J Suva, Xiang H-F Zhang, Yuxiao Zhou

Faculty, Staff and Students Publications

Breast, prostate and lung cancer cells frequently metastasize to bone, leading to disruption of the bone microstructure. This study utilized mechanical testing coupled with micro-CT imaging, digital volume correlation (DVC), and atomic force microscopy (AFM) nanomechanical testing to examine the mechanical property variations in mouse long bones (tibia) with metastatic lung cancer cell involvement, spanning from the whole-bone scale to the microstructural level. In addition, we also investigated how metastatic invasion alters the morphology of hydroxyapatite nanocrystals in bone at the nanometer scale. The biochemical composition within metastatic lesions was assessed using Raman spectroscopy and correlated with AFM mechanical testing …


Hes V20 Surpasses Galad For Hcc Detection: A Review Of Multi-Dimensional Biomarker Scores And Studies, Fouad Jaber, Hashem B El-Serag Dec 2025

Hes V20 Surpasses Galad For Hcc Detection: A Review Of Multi-Dimensional Biomarker Scores And Studies, Fouad Jaber, Hashem B El-Serag

Faculty, Staff and Students Publications

This was a narrative review of select studies published through September of 2024. We review the shift toward multi-dimensional scores such as HCC early detection screening (HES), GALAD, ASAP, and mt-HBT represents a significant advancement in biomarker research for hepatocellular carcinoma (HCC) detection. Unlike single biomarker approaches, these scores integrate various clinical and biochemical factors to enhance predictive accuracy by reflecting different complementary aspects of disease progression and HCC oncogenesis. Proper testing and validation of biomarker scores in phase 3 biomarker studies is essential before wide use can be recommended. We also review the comparative performance of biomarker scores in …


Part Ii Common Questions And Misconceptions About Creatine Supplementation: What Does The Scientific Evidence Really Show?, Jose Antonio, Ann F Brown, Darren G Candow, Philip D Chilibeck, Stacey J Ellery, Scott C Forbes, Bruno Gualano, Andrew R Jagim, Chad Kerksick, Richard B Kreider, Sergej M Ostojic, Eric S Rawson, Michael D Roberts, Hamilton Roschel, Abbie E Smith-Ryan, Jeffrey R Stout, Mark A Tarnopolsky, Trisha A Vandusseldorp, Darryn S Willoughby, Tim N Ziegenfuss Dec 2025

Part Ii Common Questions And Misconceptions About Creatine Supplementation: What Does The Scientific Evidence Really Show?, Jose Antonio, Ann F Brown, Darren G Candow, Philip D Chilibeck, Stacey J Ellery, Scott C Forbes, Bruno Gualano, Andrew R Jagim, Chad Kerksick, Richard B Kreider, Sergej M Ostojic, Eric S Rawson, Michael D Roberts, Hamilton Roschel, Abbie E Smith-Ryan, Jeffrey R Stout, Mark A Tarnopolsky, Trisha A Vandusseldorp, Darryn S Willoughby, Tim N Ziegenfuss

Faculty, Staff and Students Publications

Creatine monohydrate supplementation (CrM) is a safe and effective intervention for improving certain aspects of sport, exercise performance, and health across the lifespan. Despite its evidence-based pedigree, several questions and misconceptions about CrM remain. To initially address some of these concerns, our group published a narrative review in 2021 discussing the scientific evidence as to whether CrM leads to water retention and fat accumulation, is a steroid, causes hair loss, dehydration or muscle cramping, adversely affects renal and liver function, and if CrM is safe and/or effective for children, adolescents, biological females, and older adults. As a follow-up, the purpose …


Signaling Through National Security Lawmaking, Weijia Rao Dec 2025

Signaling Through National Security Lawmaking, Weijia Rao

Faculty Scholarship

An often-overlooked element of the ongoing TikTok saga is China’s export control law, which prohibits the sale of TikTok’s core content recommendation algorithm without prior approval from the Chinese government. This law is just one example of the extensive national security lawmaking China has undertaken in recent years. Closely paralleling similar institutions in the U.S., China has established a comprehensive national security legal framework that authorizes the government to restrict exports, sanction foreign entities, screen foreign investments, and block transactions involving cyber infrastructure.

Why turn towards legality when China has the ability to employ these actions without a formal legal …


Using Robotic Single-Port Vnotes For Gynaecological Oncology: Omentectomy In A Patient With An Ovarian Granulosa Cell Tumor-A Case Study, Chunhua Zhang, Qing Li, Fang Fang, Xiaoming Guan Dec 2025

Using Robotic Single-Port Vnotes For Gynaecological Oncology: Omentectomy In A Patient With An Ovarian Granulosa Cell Tumor-A Case Study, Chunhua Zhang, Qing Li, Fang Fang, Xiaoming Guan

Faculty, Staff and Students Publications

Background: Robotic single-port transvaginal natural orifice transluminal endoscopic surgery (RSP-vNOTES) is an emerging minimally invasive approach that combines the advantages of robotic surgery with scarless transvaginal access. Its application in gynecologic oncology remains limited, particularly for omentectomy during ovarian cancer staging.

Methods: We present the case of a 45-year-old woman with an ovarian granulosa cell tumor (GCT) who underwent supplemental staging surgery following unilateral oophorectomy. Using a single-port robotic system via the transvaginal route, hysterectomy, right salpingo-oophorectomy, and omentectomy were performed. Key technical steps included enhanced visualization with gauze placement and use of an additional robotic arm for omental traction. …


Publisher Correction: Piezo1 Regulates Meningeal Lymphatic Vessel Drainage And Alleviates Excessive Csf Accumulation, Dongwon Choi, Eunkyung Park, Joshua Choi, Renhao Lu, Jin Suh Yu, Chiyoon Kim, Luping Zhao, James Yu, Brandon Nakashima, Sunju Lee, Dhruv Singhal, Joshua P Scallan, Bin Zhou, Chester J Koh, Esak Lee, Young-Kwon Hong Dec 2025

Publisher Correction: Piezo1 Regulates Meningeal Lymphatic Vessel Drainage And Alleviates Excessive Csf Accumulation, Dongwon Choi, Eunkyung Park, Joshua Choi, Renhao Lu, Jin Suh Yu, Chiyoon Kim, Luping Zhao, James Yu, Brandon Nakashima, Sunju Lee, Dhruv Singhal, Joshua P Scallan, Bin Zhou, Chester J Koh, Esak Lee, Young-Kwon Hong

Faculty, Staff and Students Publications

No abstract provided.


Reply To Chaïbi And Tandjaoui-Lambiotte And To Young And Scott, Joan B Soriano, Francesca Polverino Dec 2025

Reply To Chaïbi And Tandjaoui-Lambiotte And To Young And Scott, Joan B Soriano, Francesca Polverino

Faculty, Staff and Students Publications

No abstract provided.


Characteristics Associated With Eurolupus Versus Modified National Institutes Of Health Cyclophosphamide Regimen Use In Children And Young Adults With Lupus Nephritis, Christine S Wang, Rebecca E Sadun, Wenru Zhou, Kristen R Miller, Stacy P Ardoin, Christine Bearer, Emily Hause, Joyce Hui-Yuen, Nicole Ling, Maria Pereira, Meredith Riebschleger, Kelly Rouster-Stevens, Aliese Sarkissian, Julia Shalen, William Daniel Soulsby, Marinka Twilt, Eveline Y Wu, Laura B Lewandowski, Scott E Wenderfer, Jennifer C Cooper Dec 2025

Characteristics Associated With Eurolupus Versus Modified National Institutes Of Health Cyclophosphamide Regimen Use In Children And Young Adults With Lupus Nephritis, Christine S Wang, Rebecca E Sadun, Wenru Zhou, Kristen R Miller, Stacy P Ardoin, Christine Bearer, Emily Hause, Joyce Hui-Yuen, Nicole Ling, Maria Pereira, Meredith Riebschleger, Kelly Rouster-Stevens, Aliese Sarkissian, Julia Shalen, William Daniel Soulsby, Marinka Twilt, Eveline Y Wu, Laura B Lewandowski, Scott E Wenderfer, Jennifer C Cooper

Faculty, Staff and Students Publications

Objective: To determine the demographic and clinical characteristics associated with use of the EuroLupus or modified National Institutes of Health (NIH) cyclophosphamide (CYC) regimen for treatment of lupus nephritis (LN) at North American pediatric centers.

Methods: A retrospective cohort study was conducted at 11 North American centers. Patients < 22 years of age with active LN treated with CYC using the EuroLupus or NIH regimen between July 2014 and June 2021 were included. Data were extracted via electronic medical record review. Demographic and clinical characteristics were compared at CYC initiation. A multivariable generalized estimating equation with logit link was fit to model EuroLupus use. An exchangeable correlation structure was used to account for correlation within centers. Independent variables were chosen using elastic net regression.

Results: The cohort consisted of 191 patients (85 EuroLupus, 106 NIH) with a median age of 15.3 years at CYC initiation. In multivariable analysis, characteristics significantly associated with EuroLupus regimen use (vs NIH regimen use) included more recent year of CYC initiation, longer disease duration, Hispanic ethnicity and Asian race (as compared …


Derivation Of Pluripotent Stem Cell Lines (Rfsci005-A, Rfsci006-A) From Siblings Harboring Identical High-Risk Complement Variants With Discordant Age-Related Macular Degeneration, Naresh Rajendran, Ajeet Singh, Wendy Runyon, Sam Hu, Ritu Kumar, Rinki Ratnapriya, Karl Csaky, Srinivasa R Sripathi Dec 2025

Derivation Of Pluripotent Stem Cell Lines (Rfsci005-A, Rfsci006-A) From Siblings Harboring Identical High-Risk Complement Variants With Discordant Age-Related Macular Degeneration, Naresh Rajendran, Ajeet Singh, Wendy Runyon, Sam Hu, Ritu Kumar, Rinki Ratnapriya, Karl Csaky, Srinivasa R Sripathi

Faculty, Staff and Students Publications

Age-related macular degeneration (AMD) is a complex disease influenced by genetic and environmental factors. Variants in the complement pathway, especially in the CFH gene, increase AMD risk, yet disease severity can differ among individuals with identical high-risk genotypes. We generated induced pluripotent stem cell (iPSC) lines from siblings carrying identical high-risk complement variants but displaying discordant AMD phenotypes. These lines provide a unique platform to study epigenetic, transcriptomic, and environmental factors driving AMD heterogeneity. By comparing differentiated retinal cells, we aim to reveal mechanisms behind variable disease susceptibility and inform personalized therapies for AMD.


Predictive Factors Of Academic Success During Transition To Undergraduate Studies In Stem Programs In Kansas, Elizabeth L. Butler Dec 2025

Predictive Factors Of Academic Success During Transition To Undergraduate Studies In Stem Programs In Kansas, Elizabeth L. Butler

Electronic Theses and Dissertations

In tThis dissertation the researcher exploreds the correlations between high school GPA, ACT Math, ACT cComposite scores, and first -semester GPA for first-time freshmen at a mid-sized university in the Midwest. This quantitative correlational study uses multiple regression analysis to discover correlations that may exist between these interval variables. Data for this study was collected through a request to the study site’s oOffice of pPlanning and aAnalysiss at the university and was all archival data at a record level for the students. Data had been collected through the admissions process and was stored in Banner and SLATE, both data management …


Community College Student Admissions Experiences, Jeremy D. Loy Dec 2025

Community College Student Admissions Experiences, Jeremy D. Loy

Electronic Theses and Dissertations

Community college students have always faced barriers to going to college and getting their degrees. Much of the research centers on the completion of their degrees. The purpose of this qualitative, phenomenological study was to understand the experiences of community college students during enrollment. To understand how community college students experience the enrollment process, the study used phenomenology to hear the experiences of students through semistructured interviews. Findings showed that three broad themes emerged from this research. First, students felt both nervous and uncertain about college, but they also recognized the importance of college to improve their lives. Second, students …