Digital Commons Network^™

The Treatment Of Obesity In The Context Of The Obesity Paradox In Patients With Heart Failure: A Narrative Review, Pamela L. Alebna, Sarah Martey, Anurag Mehta, Carl J. Lavie, Salvatore Carbone

EVMS School of Health Professions Faculty Publications

Purpose of review

While excess adiposity is a known risk factor for incident heart failure ( HF), once the condition is established, observational data suggest that increased body mass index (BMI) may confer a survival advantage. This paradox has emphasized the underlying roles of cardiorespiratory fitness (CRF), and body composition, particularly lean mass (LM), in influencing clinical outcomes.

Recent findings

In this review, we explore the multifaceted nature of the obesity paradox in HF, with a focus on emerging anti-obesity incretin-mimetic therapies, such as glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and dual GLP-1/glucose-dependent insulinotropic polypeptide (GIP) receptor agonists. These agents …

Fill The Void - An Introductory Guide For Learning Medical Imaging, Reid Faith, Peter Gahan, Adam Trusty, Aleksandr Zyskin, Chukwuka Ukekwe, Denise Nchinda, Amanda K. Burbage, Alberto E. Musto

EVMS School of Health Professions Faculty Publications

No standardized, comprehensive approach for radiological image interpretation exists among medical schools in the United States of America. In order to rectify this, we outline a model aimed to help improve how medical imaging can be taught in medical schools. The VOID (Visualization, Orientation/Observation, Identification, Description) guide is a proposed universal, stepwise approach to medical image identification, interpretation, and communication. This structured guideline is aimed at building a foundation for students in early medical education. The VOID was applied to CT (Computed Tomography), MRI (Magnetic Resonance Imaging), and x-ray modalities as integrated sessions for medical students during human anatomy laboratory. …

Mechanism-Driven Therapy For Diabetic Cardiovascular Disease, Fabian Sanchis-Gomar, Carl J. Lavie, Salvatore Carbone, Ian J. Neeland

EVMS School of Health Professions Faculty Publications

[Introduction] Diabetic cardiovascular disease is a network disorder, not a glucose-only complication

Diabetes accelerates cardiovascular (CV) target-organ damage through multiple interacting biological modules that amplify risk even when glycemia is modestly controlled^[1]. These modules include (i) adipose tissue dysfunction with altered adipokine secretion and immune-cell infiltration; (ii) ectopic lipid deposition in liver, myocardium, and perivascular/epicardial fat (iii) endothelial dysfunction with impaired nitric oxide bioavailability and heightened oxidative stress (iv) chronic kidney disease (CKD)-mediated volume, pressure, and uremic-toxin stress, and (v) autonomic and neurohormonal activation that promotes hypertension, arrhythmias, and remodeling^[1]. The clinical spectrum includes macrovascular disease …

Implementation And Clinical Utility Of Ultra-Low-Field Portable Magnetic Resonance Imaging For Postprocedural Neurological Evaluation In Ambulatory Neurosurgery: Illustrative Cases, Devan Patel, Vinay Jaikumar, Taysia P. T. Morioka, Laz Rifkin, Kenneth S. Jacoby, Jaims Lim, Anais Andrade, Aimee C. Degaetano, Pui Man Rosalind Lai, Elad I. Levy

EVMS School of Health Professions Faculty Publications

BACKGROUND

Elective endovascular neurosurgical procedures are increasingly performed in ambulatory neurosurgery centers, enabled by advances in catheter technology, safety of conscious sedation, and refined patient selection. Although complication rates are low, rapid evaluation of postprocedural neurological deficits remains critical. Conventional MRI is often impractical in outpatient or procedural settings, whereas ultra-low-field portable MRI (ULF-pMRI) systems (such as Swoop) allow bedside imaging with favorable diagnostic performance.

OBSERVATIONS

Two women in their 60s developed acute neurological deficits at an ambulatory neurosurgery center (ANSC) after diagnostic cerebral angiography in one case and elective internal carotid artery flow diversion in the other. In both …

Turnover Time In Neuroangiography Suites: Comparison Between Cases Performed At An Ambulatory Neurosurgery Center Versus A Tertiary Hospital, Pui Man Rosalind Lai, Vinay Jaikumar, Erika L. Leasher, Varun Sridhar, Gustavo M. Cortez, Aimee C. Degaetano, Elad I. Levy

EVMS School of Health Professions Faculty Publications

Background:

Efficient turnover time (TOT) and adherence to first-start time (FST) in operating and angiography suites are critical for optimizing workflow, reducing costs, and maximizing patient satisfaction. Hospitals face challenges in maintaining these metrics due to operational constraints and unexpected emergent cases. Our goal was to compare TOT, FST, and total admission time for elective cases performed in angiography suites at an ambulatory neurosurgery center (ANSC) versus a tertiary hospital (TH).

Methods:

We conducted a retrospective analysis of data for patients who underwent elective diagnostic or interventional neuroendovascular procedures at the TH or ANSC from January 2024 through October 2024. …

Automation And Autonomy In The Ivf Laboratory: Concepts And Implications For Embryologists, Jacques Cohen, Gerardo Mendizabal-Ruiz, Giles Anthony Palmer, Giuseppe Silvestri, Mina Alikani

EVMS School of Health Professions Faculty Publications

Automation is regarded as the next phase in the evolution of laboratory IVF. Despite technological advances, most laboratory procedures remain operator-dependent, contributing to variability in performance and outcomes. While automation has improved reproducibility and efficiency in many areas of medicine, its adoption in IVF has been slow. This review examines how automation may be integrated into IVF laboratories through a set of conceptual distinctions. Automation refers to the execution of procedural steps by machine-controlled systems, whereas autonomy describes the degree to which such systems can operate without human intervention. This review distinguishes between static automation, which maintains or monitors the …

Sdrc Update (Volume 6, Issue 2), Dlsu Social Development Research Center

SDRC Publications

No abstract provided.

Black Labor Matters, Michael Z. Green

American University Law Review

Black and organized workers increasingly find themselves threatened by two key outside forces: one seeking to stop anti-racism efforts via diversity, equity, and inclusion (DEI) practices and the other curtailing employees’ union organizing. This Article argues that a response must be grounded in uniquely local strategies by two specific worker coalitions. One coalition—the New Black Workers Movement (NBWM)—arose from Black Lives Matter civil rights protests in 2020 that captivated the workplace and heightened awareness about anti-Blackness and concerns of systemic racism. The other coalition—the New Labor Workers Movement (NLWM)—developed in 2020 as a workplace response to a global pandemic that …

Protecting Pregnancy: From The Pregnancy Discrimination Act To The Pregnant Workers Fairness Act, L. Camille Hébert

American University Law Review

Women have long faced challenges in balancing their employment with childbearing, facing loss of employment opportunities because of their potential for pregnancy and loss of actual employment when they became pregnant. Over the past six decades, Congress and the U.S. Supreme Court have taken actions with the potential to provide equal employment opportunity for women affected by pregnancy, but those efforts have largely failed because of the actions of lower federal courts in interpreting legislation and the Court’s decisions in ways to reduce protection for pregnancy. The most recent congressional action to protect pregnancy, the Pregnant Workers Fairness Act, was …

Citators In The Ai Age: Preserving The Human Component Through Court-Created Citators, Cody B. James

Faculty Law Review Articles

Citators have long worked behind the scenes, shaping case law and influencing how judges and lawyers view precedent. Yet their creation has been the sole realm of private publishers. As artificial intelligence (AI) is further integrated into citators’ creation, the human role is at risk of being automated. This article examines citators’ influence over substantive law, the human-in-the-loop justifications for preserving human involvement in citators’ creation, and the argument for courts to produce their own citators. By reclaiming this function, the courts can help enhance their legitimacy and preserve the human role in creating structures of legal information in the …

Geographic Distribution: Pseudacris Sierra (Sierran Treefrog). Usa: Florida: Escambia Co., Justin A. Anto, Logan P. Cutts, Jakira A. Davis, Dyrana N. Russell, Renee M. Shiska, Kayla L. O. Walker, Louis A. Somma

Papers in Herpetology

No abstract provided.

The Concept Of An Agreement In International Law, William Thomas Worster

Fordham International Law Journal

No abstract provided.

Building A Web Of Accountability: Learning From Ukraine’S Efforts To Bring Russian State Actors To Justice, Jane Stromseth

Emory International Law Review

No abstract provided.

Keynote Speaker Remarks From Ambassador Clint Williamson, Clint Williamson

Emory International Law Review

No abstract provided.

Remarks From Professor Robert C. Blitt, Robert C. Blitt

Emory International Law Review

No abstract provided.

Developing A Framework For The Direct International Responsibility Of Nonstate Armed Groups: A Model From Africa, Andrew Feinstein

Emory International Law Review

No abstract provided.

Ilr Masthead Volume 50

ILR Past Mastheads

No abstract provided.

Part Cm: Classical Mechanics, Konstantin Likharev

Essential Graduate Physics

Includes: Review of Fundamentals; Lagrangian Formalism; A Few Simple Problems; Oscillations; From Oscillations to Waves; Rigid Body Motion; Deformations and Elasticity; Fluid Mechanics; Deterministic Chaos; A Bit More of Analytical Mechanics

Part Qm: Quantum Mechanics, Konstantin Likharev

Essential Graduate Physics

Includes: Introduction; 1D Wave Mechanics; Higher Dimensionality Effects; Bra-ket Formalism; Some Exactly Solvable Problems; Perturbation Theories; Open Quantum Systems; Multiparticle Systems; Introduction to Relativistic Quantum Mechanics; Making Sense of Quantum Mechanics

Front Matter, Konstantin Likharev

Essential Graduate Physics

Includes: Copyright and License; Preface; Disclaimer; Versions, Corrections, and Acknowledgments; Solution Request Templates; Notation; General Table of Contents

The Role Of Conflicting Cognitions In Changing Hazardous Consumer Behaviour, Krzysztof Kubacki, Krzysztof Stepaniuk, Dariusz Siemieniako, Karolina Małagocka, Chrystyna Misiewicz

Plymouth Business School

Despite diverse approaches deployed worldwide to address harmful alcohol consumption, understanding binge drinking as a hazardous consumption behaviour remains a pressing issue in marketing and consumer behaviour research. Thus, this study examines the role of cognitive dissonance – and its absence – in facilitating transitions between different phases of binge drinking. Drawing on 38 biographical interviews conducted in Australia, the Netherlands, Poland, and the United States, we identify six instances where cognitive dissonance, or the absence thereof, contributes to the transition into, between, and out of phases of binge drinking. By examining conflicting cognitions that emerge from the gaps between …

Developing An End-To-End Ecosystem Model To Inform Management Of Hudson River Estuary And New York Bight Ecosystem, Xiangyan Yang

Electronic Dissertations and Theses, 2010-current

Ecosystem models provide a powerful framework for evaluating complex anthropogenic impacts because they explicitly represent interactions among species and between biological and physical components of ecosystems. Preliminary analyses indicated that increasing temperature is a major driver of shifts in species distributions and biomass within the Hudson River Estuary and New York Bight (HRE-NYB), the focal region of this dissertation. This dissertation develops an end-to-end (E2E) ecosystem modeling framework to investigate the ecological consequences of climate-induced species distributional shifts in this climate-sensitive region. Habitat suitability index models were developed and validated using sea surface temperature as a key thermal indicator to …

Structural And Biochemical Insights Into Phospholipase D Function And Its Small Gtpase Stimulators, Douglas Jay Marr

Electronic Dissertations and Theses, 2010-current

Phospholipase D1 (PLD1) and D2 (PLD2) are lipid metabolizing enzymes that produce phosphatidic acid and contribute to pathologies such as cancer, neurodegeneration, and cardiovascular diseases. Recently, the ARF-like GTPase 11 (ARL11) was identified as an activator of PLD1, but the mechanism of this stimulation remained unknown. Here, we use in vitro biochemical assays and structural predictions to determine that ARL11 interacts with PLD1 using three adjacent, biochemically distinct interfaces, and that the ends of PLD1’s disordered loop form ordered structures to facilitate these interactions. Both PLD1 and PLD2 are peripheral membrane proteins that have differing subcellular localization important for their …

Fundamentals Of Speech, Steelman Library, David Yates

Syllabus Repository

No abstract provided.

Injectable Borate/Borosilicate Bioactive Glass Systems For The Regeneration Of Hard Tissue – A Critical Review Of The Literature, S. Sina Mohammadi, Sunjeev S. Phull, Ryan J. Gilbert, Mark R. Towler

Chemical and Biochemical Engineering Faculty Research & Creative Works

Bone defects caused by trauma, infection, or tumor resection remain difficult to treat because successful repair requires both structural restoration and control of the local pathological microenvironment. Osteolysis, defined as pathological bone resorption, is central to many of these conditions and is commonly driven by excessive osteoclast activity. Clinically translated injectable products such as NovaBone® Putty demonstrate the value of moldable bioactiveglass grafts for defect filling; however, conventional silicate bioactive glasses are permanent and provide limited therapeutic ion release. This limitation has motivated the development of injectable borate bioactive glass (B-BGs) and injectable borosilicate bioactive glass (BS-BG) systems as more …

Foreword, Veronica Degennaro

Emory International Law Review

No abstract provided.

Being Accountable To Our Grandchildren: Generational Accountability And The Eccc”, Alexandra A.K. Meise

Emory International Law Review

No abstract provided.

From Crime To Constitutional Crisis: The Legality Of El Salvador’S State Of Exception, Alex Jacobs

Emory International Law Review

No abstract provided.

Two Heads Are Better Than One: Integrating International Law And Global Public Health Approaches To Firearm Violence To Promote Public Safety And Human Rights, Arturo J. Carrillo, Jonathan Lowy

Emory International Law Review

No abstract provided.

Esg Is Not Libertarian: A Response To Jonathan Macey, Allen Mendenhall, Daniel Sutter

Emory Business Law Review

Investing, like any market activity, is voluntary. Investors may invest however they wish, whether to maximize returns, minimize risk, or support what they view as good causes. Is the current Environmental, Social and Governance (ESG) movement a libertarian embrace of socially responsible investing, as Jonathan Macey has argued? We answer with a definite no for several reasons. Government policies impel much ESG investment, most prominently through clean energy transition and financial regulations. Most ESG investment dollars stem not from investor decisions but from potential opportunism by managers of public pensions and sovereign wealth funds. Much investor activism for ESG results …