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Articles 103711 - 103740 of 5150686
Full-Text Articles in Entire DC Network
Pressure Field Estimation From 2d-Piv Measurements: A Case Study Of Fish Suction-Feeding, Jensine C. Coggin, Duvall Dickerson-Evans, Erin E. Hackett, Roi Gurka
Pressure Field Estimation From 2d-Piv Measurements: A Case Study Of Fish Suction-Feeding, Jensine C. Coggin, Duvall Dickerson-Evans, Erin E. Hackett, Roi Gurka
Physics and Engineering Science
Particle image velocimetry (PIV) flow measurements are common practice in laboratory settings in a wide variety of fields involving fluid dynamics, including biology, physics, engineering, and medicine. Dynamic fluid pressure is a notoriously difficult property to measure non-intrusively, yet its variation is a driving flow force and critical to model correctly. Techniques have been developed to estimate the pressure from velocity and velocity gradient measurements. Here, we highlight a novel application of boundary conditions when applying such pressure estimation techniques based on two-dimensional PIV data; the novel method is especially relevant to problems with complex boundary conditions. As such, it …
Front Matter, Arthit Jiamrattanyoo
Spatial And Temporal Analysis Of Summer Rainfall Characteristics In Upper Northeastern Thailand Using Weather Radar Data, Nawin Sermsook
Spatial And Temporal Analysis Of Summer Rainfall Characteristics In Upper Northeastern Thailand Using Weather Radar Data, Nawin Sermsook
Journal of Letters
This research aims to investigate and analyze spatial and temporal characteristics of daily rainfall which include rainfall amount, proportion of areas with heavy (35-90 mm/day) and extreme (>90 mm/day) rainfall intensity, numbers of extreme rainfall clusters, average size of extreme rainfall clusters, and orientation of extreme rainfall areas in the upper northeastern region of Thailand during the summer season (March to May) from 2017 to 2020. Rainfall data were obtained from Sakon Nakhon weather radar station. Radar reflectivity was converted to hourly rainfall amount using Z-R relationship for northeastern Thailand. It was found that the spatially variable bias correction …
Application Of Metres For Sentimental Purposes In Sanskrit Literature: With References To Sanskrit Play Entitled Ratnāvalī Of King Śrī Harṣavardhana, Aroonwan Kongmebhol
Application Of Metres For Sentimental Purposes In Sanskrit Literature: With References To Sanskrit Play Entitled Ratnāvalī Of King Śrī Harṣavardhana, Aroonwan Kongmebhol
Journal of Letters
Currently, research on the relationship between metres (chandas) and literary sentiments (rasa) in classical Sanskrit poetry is quite meagre. This research aims to investigate the application of metres for sentimental purposes in Sanskrit play entitled Ratnāvalī of King Śrī Harṣa Vardhana. The research subject highlights selected thirteen stanzas, each of which the sentiment is apparent, from the Ratnāvalī. The methodology of the research consists of a textual translation from Sanskrit to Thai as well as an analysis on the literary sentiments, the schemes of metres, including properties of vowels and consonants used in the …
From Plague To Cholera: The Prevention And Treatments Of Cholera In Thailand, 1820–1959, Suwasadee Photpun
From Plague To Cholera: The Prevention And Treatments Of Cholera In Thailand, 1820–1959, Suwasadee Photpun
Journal of Letters
This article aims to explore the history of cholera in Thailand from 1820 to 1959, focusing on disease prevention and the evolving treatment methods for cholera patients across different historical periods. The article argues that knowledge about pathogens and the discovery of Vibrio cholerae as the cause of cholera did not lead to significant changes in cholera prevention and treatment methods before the mid-20th century. Methods like maintaining hygiene, implementing quarantine, and treating the disease with Western medicine and intravenous saline infusions were already known and utilized before the acceptance of germ theory and before the discovery of bacteria as …
African Surrealism In Federico García Lorca’S Poeta En Nueva York: A Study Of Racial Identity And Social Critique, Narut Chaosakun
African Surrealism In Federico García Lorca’S Poeta En Nueva York: A Study Of Racial Identity And Social Critique, Narut Chaosakun
Journal of Letters
This article presents a comprehensive analysis of Federico García Lorca’s surrealist poetry concerning the Black ethnic group, focusing specifically on the poems “Norma y paraíso de los negros” and “El rey de Harlem” from his collection Poeta en Nueva York. The study employs the perspective of Afrosurrealism, an artistic and literary movement that emerged later in the United States, integrating an understanding of the distinctive surrealist symbols and “poetic logic” characteristic of Lorca’s surrealism. This analysis elucidates the intersection between the contextual background and the underlying ideas of the two poems, derived from Lorca’s personal experiences, and the Afrosurrealism …
The Impact Of Parents’ School Choices Towards Schools And Students: A Case Study Of Secondary Schools In Inner Bangkok, Krittin Klaimee, Petchpilai Lattanan
The Impact Of Parents’ School Choices Towards Schools And Students: A Case Study Of Secondary Schools In Inner Bangkok, Krittin Klaimee, Petchpilai Lattanan
Journal of Letters
Parents typically select the most suitable school for their children based on socioeconomic factors and geographic factors which impact on the ease of travel. With the decline in the student-age population and ongoing urban changes, schools have been significantly impacted, prompting them to adapt to the increasing competition. These impacts not only affect the schools themselves but also the students. This study aims to examine the impact of parental school choice decisions on secondary schools and students in inner Bangkok through in-depth interviews with teachers and focus group discussions with students. The findings reveal that schools with different service areas …
A Comparative Study Of Animal Proverbs In Myanmar And Thai Languages, Thet Su Mon, Sunantha Thetsuk, Su Su Khin
A Comparative Study Of Animal Proverbs In Myanmar And Thai Languages, Thet Su Mon, Sunantha Thetsuk, Su Su Khin
Journal of Letters
The objectives of this study are to: 1) analyze and compare animal proverbs in Myanmar and Thai, and 2) analyze the values that are reflected in animal proverbs in Myanmar and Thai. The research methodology used for this study was qualitative. According to objective 1, the study's findings can be divided into three categories: 1) Myanmar and Thai proverbs that are similar and use the same kinds of animals; 2) Myanmar and Thai proverbs are similar and use different kinds of animals; and 3) Myanmar and Thai proverbs are similar and use non animal things. The findings of the analysis …
Phra Malai Of Wat Thewa Sangkharam: An Orthographic Analysis And Its Social And Cultural Connections Within The Local Context Of Kanchanaburi, Jaturong Phiromya, Phatchaya Luangdaeng, Kriangkri Thongsri
Phra Malai Of Wat Thewa Sangkharam: An Orthographic Analysis And Its Social And Cultural Connections Within The Local Context Of Kanchanaburi, Jaturong Phiromya, Phatchaya Luangdaeng, Kriangkri Thongsri
Journal of Letters
This research article aims to 1) analyze the Phra Malai manuscript of Wat Thewasangharam from a paleographic perspective, and 2) examine the interrelationship between this manuscript and the local society and culture of Kanchanaburi. A qualitative research methodology was employed, incorporating fieldwork data collection and documentary analysis and synthesis. The findings indicate that 1) the Phra Malai manuscript of Wat Thewasangharam is a Buddhist didactic text inscribed on white Thai folding books (samut thai khao), written in Khmer–Pali and Khmer–Thai scripts, and recorded in both Pali and Thai. The script characteristics correspond to the early to mid-Rattanakosin period, spanning the …
Knowledge Transfer For Improvement Of Local Administrative Organizations Capacities In Flood Hazard Risk Management Using Participatory Geographic Information System At Dan Makham Tia, Kanchanaburi, Komsan Sriboonruang, Nirut Jorncharoen, Malinee Kumkrua
Knowledge Transfer For Improvement Of Local Administrative Organizations Capacities In Flood Hazard Risk Management Using Participatory Geographic Information System At Dan Makham Tia, Kanchanaburi, Komsan Sriboonruang, Nirut Jorncharoen, Malinee Kumkrua
Journal of Letters
This research aims to (1) create risk and vulnerability maps of flood hazard using participatory geographic information systems in Dan Makham Tia District, Kanchanaburi Province, (2) transfer knowledge on flood hazards risk management based on data from the flood risk and vulnerability maps to local administrative organizations ; and (3) transfer the action plans based on the maps to improve the capacities of local administrative organizations in flood hazard risk management. The sample groups were officers of Charakhe Phuek Subdistrict Administrative Organization, disaster prevention and mitigation volunteers, public health volunteers, rescue workers, and disaster victim households. The research framework included …
Parameter Identification Of A Pi Controller For A Wind Energy Conversion System Based On Dfig, Mariam Hesham, Dina S. M. Osheba, Mahmoud M. Khater
Parameter Identification Of A Pi Controller For A Wind Energy Conversion System Based On Dfig, Mariam Hesham, Dina S. M. Osheba, Mahmoud M. Khater
Mansoura Engineering Journal
In this work, three methods are proposed to identify parameters of PI controllers used for wind energy conversion systems based on DFIG. Mathematical model of generator and grid side system is depicted. Three tuning methods; bode-plot, pole-placement, and MATLAB tuner are used for grid side and rotor side converter controllers’ design. Wind turbine system with PI controller parameters obtained using the mentioned method is investigated via MATLAB/SIMULINK under three different scenarios. The wind system is subjected to step wind speed change, random wind speed, and sever symmetrical voltage dip in the grid. The handled comparison illustrates that the pole-placement tuning …
State Of California Cannabis Reporting, University Of Mississippi – National Center For Cannabis Research And Education
State Of California Cannabis Reporting, University Of Mississippi – National Center For Cannabis Research And Education
California
No abstract provided.
How Gas Flow And Distance From The Laser Focus Affects Powder Deposition Focus Concentration In A Lens Machine, Max A. Siefert
How Gas Flow And Distance From The Laser Focus Affects Powder Deposition Focus Concentration In A Lens Machine, Max A. Siefert
Mechanical Engineering and Materials Science Independent Study
Additive manufacturing via Direct Layer Deposition (DLD) is what the Laser Net Engineered Shaping or LENS machine is used to create components using metallic powders and a high powdered laser in the Flores Lab. In the lab this machine is used to create metallic alloys with high degrees of accuracy, but it has been difficult to get the accuracy required. By changing two variables, focus height and carrier gas flow rate, the concentration of the powder in a certain radius can be changed. The dot concentration and diameter were gotten using image analysis. It was found the LPM has a …
A Pouch Of Trouble For The Pancreas: Unmasking A Case Of Lemmel Syndrome, Aravindharaj Tamilselvan, Sabari Ramesh
A Pouch Of Trouble For The Pancreas: Unmasking A Case Of Lemmel Syndrome, Aravindharaj Tamilselvan, Sabari Ramesh
Manipal Journal of Medical Sciences
Lemmel syndrome is a rare cause of biliary and pancreatic obstruction arising from periampullary duodenal diverticula. We report a 72-year-old woman presenting with acute pancreatitis, biliary dilation, and a periampullary diverticulum causing distal CBD compression. Multimodality imaging, including CT and MRCP, established the diagnosis. Although ERCP was advised, the patient declined and improved with conservative management. Early recognition of this uncommon entity is essential to prevent recurrent pancreatobiliary complications.
Improvement Of Technology And Control And Management Systems Of The Plant Oil Refination Process, Elyor Samadov
Improvement Of Technology And Control And Management Systems Of The Plant Oil Refination Process, Elyor Samadov
Chemical Technology, Control and Management
The article examines modern approaches to modernizing vegetable oil refining processes from the perspective of increasing energy efficiency, environmental friendliness, and final product quality. Traditional and innovative technologies are analyzed, with a focus on the implementation of membrane filtration, automated control systems, heat exchange complexes, and renewable energy sources. It has been shown that the use of intelligent control systems, high-precision membrane filters, and heat regeneration allows for a 25% reduction in energy consumption, a 20% reduction in greenhouse gas emissions, and a significant improvement in acidity, color, and impurity content in the product. The obtained results show the effectiveness …
Analog Systems Of Physical Quantities And Their Graph Models In Determining The Parameters Of Mechatronic Modules, Temurbek Omonboevich Rakhimov, Elmira Eshmurod Qizi Raxmanova, Guzal Khujaniyazova
Analog Systems Of Physical Quantities And Their Graph Models In Determining The Parameters Of Mechatronic Modules, Temurbek Omonboevich Rakhimov, Elmira Eshmurod Qizi Raxmanova, Guzal Khujaniyazova
Chemical Technology, Control and Management
This article is dedicated to the analogy systems of physical quantities and their graph models in determining the parameters of mechatronic modules. It presents the general sets and fundamental laws of analogy systems of physical quantities and their elements for determining the parameters of mechatronic modules. Based on the general sets and fundamental laws of analogy systems of physical quantities and their elements, principles have been developed for mechatronic modules with a heterogeneous structure consisting of electrical, magnetic, and mechanical parts. In these modules, the field as a form of matter exists, forming the basis for developing mathematical models to …
Improving Self-Diagnostic Methods Of Flow Measurement Systems Based On Artificial Intelligence, Elbek Ortikov
Improving Self-Diagnostic Methods Of Flow Measurement Systems Based On Artificial Intelligence, Elbek Ortikov
Chemical Technology, Control and Management
The article examines methods for improving self-diagnostics of consumption measurement systems based on artificial intelligence in the context of industry digitalization and the development of cyber-physical systems. It has been shown that traditional flow meters used to measure the flow rate of liquids and gases are subject to mechanical, hydraulic, electronic, and hidden failures, which reduce the accuracy and reliability of measurements. A justification for the need to transition from classical maintenance methods to intelligent self-control methods that ensure the detection of anomalies and hidden malfunctions in real time is presented. A multi-level architecture of intelligent self-diagnosis is proposed, including …
Performance Assessment Of Operators Under Digital Simulator-Based Training In Automated Industrial Systems, Kamola Abdullaeva
Performance Assessment Of Operators Under Digital Simulator-Based Training In Automated Industrial Systems, Kamola Abdullaeva
Chemical Technology, Control and Management
This article proposes a comprehensive approach to training process operators, based on computer simulators integrated with digital twins, SCADA/DCS systems, real production data, and artificial intelligence algorithms. This approach is particularly relevant given the increased requirements for safety, productivity, and reliability of industrial facilities, as human factors are often the main cause of accidents (up to 60-80% of cases). The architecture of the simulator complex is designed to accurately emulate steady-state, transient, and pre-emergency operating modes of equipment, which are not achievable under actual production conditions. The experiment compared the training effectiveness of two groups of operators: one that used …
Review And Analysis Of Methods And Techniques For Refining Vegetable Oils, Umidjon Ruziev, Marufjon K. Shodiev
Review And Analysis Of Methods And Techniques For Refining Vegetable Oils, Umidjon Ruziev, Marufjon K. Shodiev
Chemical Technology, Control and Management
This article provides a comparative analysis of the main methods of vegetable oil refining: alkaline (chemical), physical, and combined. It examines the stages of the technological process and the applicability of each method for various types of oils (palm, soybean, cottonseed, sunflower, rapeseed, etc.). Attention is paid to energy consumption at the stages of neutralization, washing, drying, and deodorization, as well as the impact of equipment performance on specific energy consumption. Approximate calculations of the distribution of thermal and electrical energy during the processing of 1 kg of oil are provided. It is noted that physical refining, despite the high …
Expansion Of The Functionality Of Discrete Fiber-Optic Liquid Level Sensors, Azimjon Mamadaliyevich Khusanov, Yuriy Gennadyevich Shipulin
Expansion Of The Functionality Of Discrete Fiber-Optic Liquid Level Sensors, Azimjon Mamadaliyevich Khusanov, Yuriy Gennadyevich Shipulin
Chemical Technology, Control and Management
The article examines the problems and prospects of creating discrete fiber-optic liquid level gauges. Functional diagrams of single-channel and multi-channel discrete fiber-optic liquid level meters are presented. Examining the challenges of keeping this system running continuously reveals that sustaining its required reliability necessitates replacing malfunctioning measurement systems with operational ones. Investigations into differential equation models demonstrate that system recovery and failure events occur independently and follow a Poisson distribution pattern.
Investigation Of Nonlinear Magnetic Circuits Of Measuring Transducers With A Special Parameter Distribution Structure, Javhar Sulton O'G'Li Fayzullayev
Investigation Of Nonlinear Magnetic Circuits Of Measuring Transducers With A Special Parameter Distribution Structure, Javhar Sulton O'G'Li Fayzullayev
Chemical Technology, Control and Management
The article proposes a new analytical method for investigating nonlinear magnetic circuits with a special structure of parameter distribution. The method is based on introducing into the system of nonlinear differential equations of such circuits the condition that the second derivative of the magnetic flux along the length of the circuit is equal to zero, as well as on the assumption that one of the geometric parameters of the studied magnetic circuit – the size of the air gap between the ferromagnetic rods, their thickness, width, or the linear value of the number of turns of the distributed excitation winding …
Comprehensive Mechatronic Design Methodology For 6-Dof Stationary Lower Limb Rehabilitation Exoskeleton Robot With Safety-Integrated Control Architecture, Javlonbek Rakhmatillaev Mr., Nodirbek Kimsanboyev Mr., Umidjon Takabaev Mr., Zafar Juraev3 Dr.
Comprehensive Mechatronic Design Methodology For 6-Dof Stationary Lower Limb Rehabilitation Exoskeleton Robot With Safety-Integrated Control Architecture, Javlonbek Rakhmatillaev Mr., Nodirbek Kimsanboyev Mr., Umidjon Takabaev Mr., Zafar Juraev3 Dr.
Chemical Technology, Control and Management
This paper presents the mechatronic design of a proposed six-degree-of-freedom (6-DOF) stationary lower limb rehabilitation exoskeleton (SLLRE) robot, developed through a comprehensive mechatronic design methodology that includes mechanical design, actuator and sensor selection, and the development of a control structure based on a safety-oriented control approach. The proposed 6-DOF SLLRE mechanical design introduces a comprehensive mechanical structure comprising bilateral hip, knee, and ankle joints, degrees of freedom, joint ranges of motion, human parameters for rehabilitation training, as well as the frames and structural elements of the proposed system. Furthermore, the selection of appropriate sensors, actuators, and control architecture for the …
Design Of A Fuzzy Set-Point Tracking Controller Based On The State-Dependent Control Characteristics Of Fuzzy Logic And Pid For Temperature Control Systems In Electrical Equipment, Rahim Mammadzada
Chemical Technology, Control and Management
This paper presents a Fuzzy-SPT (Fuzzy Set-Point Tracking) controller designed to combine the strengths of FLC (Fuzzy Logic Control) and PID (Proportional-Integral-Derivative) control while mitigating their limitations across varying operating conditions. Inspired by state-dependent reasoning but implemented within a single controller, the method uses internal logic to adapt the control effort across different operating regions. FLC handles rapid changes and nonlinear transients, enabling fast system response without overshoot, while PID-like integral action is activated when the FLC reaches steady state or enters a threshold region near the set point, eliminating residual errors and maintaining stable performance. By applying each behavior …
Empirical Analysis Of Machine Learning Models For Predicting Equipment Failures Using Iot Sensor Data, Yusuf Shodiyevich Avazov
Empirical Analysis Of Machine Learning Models For Predicting Equipment Failures Using Iot Sensor Data, Yusuf Shodiyevich Avazov
Chemical Technology, Control and Management
This article examines the problem of detecting and predicting industrial equipment faults using IoT sensor data through machine learning techniques. Sensor readings such as temperature, vibration, pressure, voltage, and current, as well as FFT-based features, were statistically analyzed. Class imbalance and low signal informativeness were identified as key factors limiting model accuracy. Results obtained from Logistic Regression, Random Forest, and XGBoost models were comparatively evaluated, showing that when ROC-AUC values remain around 0.5, distinguishing fault and non-fault states becomes challenging. Correlation and feature-importance analyses confirmed the absence of strong dominant indicators. The findings highlight the need to improve sensor architecture …
Current Trends In Industrial Gas Furnace Control And Monitoring Systems, Utkir Uktam O'Gli Kholmanov
Current Trends In Industrial Gas Furnace Control And Monitoring Systems, Utkir Uktam O'Gli Kholmanov
Chemical Technology, Control and Management
This paper presents a critical review of modern control methods applied to industrial gas-fired furnaces. Conventional PID controllers and their advanced modifications, including Advanced Process Control (APC) and cascade control schemes, are analyzed alongside Model Predictive Control (MPC) approaches. In addition, intelligent control algorithms—such as fuzzy logic and neuro-fuzzy systems (Fuzzy, ANFIS)—are examined. The study also considers advanced sensing technologies, including Tunable Diode Laser Absorption Spectroscopy (TDLAS), acoustic pyrometry, and infrared pyrometers, as well as digital twins and CFD-based modeling techniques. Particular attention is given to a comparative evaluation of control strategies based on key performance criteria, including energy efficiency, …
Skeleton-Based Human Action Recognition Using Spatio-Temporal Latent Features With A Gcn Model, Avazjon Marakhimov, Kabul Khudaybergenov, Mominov Zakhriddin
Skeleton-Based Human Action Recognition Using Spatio-Temporal Latent Features With A Gcn Model, Avazjon Marakhimov, Kabul Khudaybergenov, Mominov Zakhriddin
Chemical Technology, Control and Management
Owing to its resilience to visual noise and viewpoint variations, skeleton-based analysis has become a cornerstone of human action recognition research. Despite its practical significance, existing methodologies often suffer from a reliance on single-stream skeletal representations, which fail to encompass the full complexity of action features. This study introduces Latent Features for Human Action Recognition (LFHAR), a novel architecture designed to overcome these limitations by utilizing diverse spatio-temporal latent representations for improved feature extraction. The approach applies graph-based transformations to individual skeletal frames in temporal sequences, then arranges the derived graph features into spatio-temporal matrices. Evaluation of standard datasets demonstrates …
Models And Algorithms Of Control Mechanisms In Information Exchange Processes, Madina M. Fozilova, Dilshoda N. Uchqunova
Models And Algorithms Of Control Mechanisms In Information Exchange Processes, Madina M. Fozilova, Dilshoda N. Uchqunova
Chemical Technology, Control and Management
In modern digital systems, efficient and reliable information exchange is essential for the stability of corporate systems. Traditional data management models struggle to detect and eliminate invalid, incomplete data at early stages, resulting in reduced accuracy and system inefficiency. This article proposes an advanced framework for controlling information exchange processes through the development of a Verification and Filtering algorithm. The algorithm operates within a multi-layered conceptual model that includes data input, control, validation, optimization, and decision layers. Acting as the core component, the Verification and Filtering algorithm distinguishes valid from invalid records in real time, ensuring data integrity before storage. …
Composite Flours For Sustainable Food Systems: Integrating Nutritional, Environmental, And Climate Resilience Strategies, Rashmi H. Poojara, Soumya P S, Alvina Rose, Niva Somarajan
Composite Flours For Sustainable Food Systems: Integrating Nutritional, Environmental, And Climate Resilience Strategies, Rashmi H. Poojara, Soumya P S, Alvina Rose, Niva Somarajan
Journal of Environmental Science and Sustainable Development
Composite flour blends prepared from cereals, millets, tubers, legumes, and vegetables have gained increasing attention due to their potential to enhance nutritional quality, improve functional properties, and support sustainable food systems. Previous studies have largely focused on individual nutritional or functional attributes, with limited integration of environmental and health perspectives. This review aimed to systematically analyze how composite flours simultaneously influence nutritional quality, functional performance, health relevance, and environmental sustainability within a unified analytical framework. A systematic literature review was conducted following PRISMA guidelines. Peer-reviewed studies published between 2014 and 2025 were retrieved from PubMed, Scopus, Web of Science, and …
Using Machine Learning To Predict Women At Risk Having A Child With Congenital Heart Defects, Amany M. Abdo Prof., Asmaa M. Mosallam Ms., Laila M. Abdelhamid Assoc.Prof.
Using Machine Learning To Predict Women At Risk Having A Child With Congenital Heart Defects, Amany M. Abdo Prof., Asmaa M. Mosallam Ms., Laila M. Abdelhamid Assoc.Prof.
Information Systems
Congenital heart defects (CHD) are heart malformations present at birth, affecting heart function and circulation, and are a leading cause of infant mortality. CHD can result from genetic, environmental, and maternal health factors, making early detection essential. Early diagnosis allows for timely intervention, reducing risks like heart failure or stroke. In countries like Egypt, CHD often remains undiagnosed due to limited healthcare resources. Artificial intelligence (AI) can improve early detection by analyzing risk factors. This study presents a predictive model for CHD using maternal and paternal health factors. Data was collected from 571 families: 260 with a CHD-affected child and …
Role Of Gut Microbiome In Oncogenesis And Oncotherapies, Renuka Sri Sai Peddireddi, Sai Kiran Kuchana, Rohith Kode, Saketh Khammammettu, Aishwarya Koppanatham, Supriya Mattigiri, Harshavardhan Gobburi, Suresh K. Alahari
Role Of Gut Microbiome In Oncogenesis And Oncotherapies, Renuka Sri Sai Peddireddi, Sai Kiran Kuchana, Rohith Kode, Saketh Khammammettu, Aishwarya Koppanatham, Supriya Mattigiri, Harshavardhan Gobburi, Suresh K. Alahari
School of Graduate Studies Faculty Publications
The gut microbiome has emerged as a key regulator of human health, influencing not only metabolism and immunity but also the development and treatment of cancer. Mounting evidence suggests that microbial dysbiosis contributes to oncogenesis by driving chronic inflammation, producing genotoxic metabolites, altering bile acid metabolism, and disrupting epithelial barrier integrity. At the same time, the gut microbiome significantly modulates the host response to oncotherapies including chemotherapy, radiotherapy, and especially immunotherapy, where microbial diversity and specific taxa determine treatment efficacy and toxicity. This review synthesizes current evidence on the role of the gut microbiome in both oncogenesis and oncotherapies, focusing …