Digital Commons Network^™

Toward Interpretable Multi-Omics Multimodal Biomedical Artificial Intelligence, Yanjun Lyu

Computer Science and Engineering Dissertations

The complexity of human disease arises from biological processes that unfold across multiple scales, from molecular variation through cellular function, tissue organisation, brain phenotypes, each of which is associated with distinct measurement modalities, regularities, and characteristic. Contemporary biomedical artificial intelligence has brought the opportunity to reveal the complexity with in; however, its methodological default, in which models are trained on most readily available modality, does not adequately engage with the multi-scale connected structure by which biological meaning is constituted. The research area of multi-omics and multi-modal AI for biomedicine remains at an early exploratory stage, and the work presented in …

Pre-Training And Interpretability In Deep Learning Models, Weizhi An

Computer Science and Engineering Dissertations

In the evolving field of artificial intelligence, the efficacy of deep learning models is often gated by the quality of their training and the clarity of their decision-making processes. This dissertation addresses these crucial challenges by focusing on two key areas: enhancing pre-training strategies and improving model interpretability. Our approach is twofold, integrating novel pre-training methodologies that embed domain-specific knowledge early in the model training process, and developing advanced techniques for disentangling and clarifying the decision-making mechanisms within these models. The first direction of our research employs MoDNA, a motif-oriented pre-training framework specifically designed for DNA language models. By leveraging …

Uncertainty Quantification, Propagation & Conjunction Assessment In Orbital Mechanics Using Generalized Polynomial Chaos Expansion & 2-Dimensional Conjunction Plane Analysis Techniques, Monalisa Karim

Mechanical and Aerospace Engineering Theses

Uncertainties, that are inherent to dynamic models, can be associated with state initial conditions, force modelling errors, navigation and actuation errors. In system modelling stochastic differential equations are used to represent dynamic phenomena with uncertainties, for which the solutions are probability density functions of quantities of interest characterizing the realization of the stochastic processes. In Polynomial Chaos Expansion (PCE) propagation, these solutions are represented as weighted sums of multivariate spectral polynomials that are functions of the input random variables. Generalized polynomial chaos expansion (gPC) is an extension to the original homogenous PCE which projects the random solution onto a basis …

Influence Of Microbial Communities And Dilute Heavy Metals In Green Manure On Growth In Lactuca Sativa, Robert Lemay

Student Research Projects

This experiment investigated the effects of a green manure (Lemna minor, common duckweed) grown in varying levels of heavy metals and inoculated with local microbiomes on a crop (Lactuca sativa, volcana lettuce). The growth and health of the duckweeds were measured via root length and biomass, and the health of the lettuce crop was measured via head diameter and biomass.  Two levels of heavy metal concentrations were based on real-world stormwater runoff data to mimic an agricultural environment where accumulation of metals in local water bodies may be absorbed into green manure duckweeds. One microbial treatment and …

Limitations Of Reproductive Manipulation By Bacterial Endosymbionts In A Spider Host, Jordyn D. Proctor

Theses and Dissertations--Entomology

Maternally inherited bacterial endosymbionts are common in arthropods. Many of these bacteria manipulate host reproduction to favor the production of infected females, thereby increasing bacterial prevalence in the host population, even if cost is incurred to the host. However, there are also many factors that may inhibit symbionts’ ability to spread in host populations, including environmental constraints, symbiont-imposed costs on the host, interactions with co-infecting bacteria, or host biology. I explored two aspects of symbiont biology within a spider host, Mermessus fradeorum (Linyphiidae), which has varying combinations of up to five different bacterial endosymbionts in local populations: Rickettsiella, Tisiphia …

Impacts Of Livestock Dewormers On Dung Beetle Foraging Choices Across Spatial Scales, Madison L. Kluge

Theses and Dissertations--Entomology

Dung beetles provide ecosystem services in pasture systems but are vulnerable to chemical residues in livestock dung. Parasiticides containing macrocyclic lactones (MLs) are used to control parasites in livestock and are excreted unmetabolized in dung, exposing non-target organisms to these compounds. We used a multi-scale approach to examine whether ML residues alter dung beetle foraging ecology. At the field scale, we assessed dung beetle abundance and community composition using traps baited with dung from untreated cattle and cattle treated with ivermectin, moxidectin, or eprinomectin across eight farms and natural areas. At a smaller scale, we conducted behavioral assays to quantify …

Social Protection To Foster Inclusive, Resilient Early Childhood Education In Kenya, Uganda, And Tanzania, Nyagwegwe Wango

Institute for Educational Development, East Africa

In order to evaluate the efficacy of systems approaches in enhancing early childhood education (ECE), this study summarizes outcomes from the SESEA and F4L programs in Kenya, Tanzania, and Uganda. The study investigates how context-responsive ECE, social-emotional learning (SEL), and social protection (SP) interventions contribute to improvements in teaching practices, inclusion, and learner outcomes using mixed-methods data, including teacher surveys, classroom observations, and policy analysis. The findings show significant improvements in inclusive classroom practices, gender-sensitive pedagogy, and teacher confidence, especially when reflective peer learning and continuous mentoring are incorporated. Children’s academic performance and well-being have been linked to the integration …

Spatial Clustering And Determinants Of Dengue Incidence Among The Young Population Of Northern Thailand During The Covid-19 Pandemic, Sopida Supotina, Kasama Pooseesod, Tassanee Silawan, Nattapong Puttanapong, Sayambhu Saita

NAKHARA (Journal of Environmental Design and Planning)

Dengue infection remains a significant public health concern in Thailand, particularly among young populations. The emergence of COVID-19 introduced additional complexity to disease surveillance and control efforts. This study aimed to determine the spatial clustering and determinants of dengue incidence among individuals under 25 years of age in Northern Thailand during the COVID-19 pandemic. Ecological analysis was conducted across 103 districts in eight northern provinces. District-level dengue incidence rates of individuals under 25 years of age for 2021 were calculated and analyzed using global Moran’s I and local indicators of spatial association (LISA) to detect spatial clustering. Bivariate LISA was …

Localized Ks Assessment For Bioretention In Thailand : Improving Swmm Accuracy, Chulalux Wanitchayapaisit, Damrongsak Rinchumphu, Prattakorn Sittisom, Thidarat Kridakorn Na Ayutthaya, Chana Sinsabvarodom, Oleg Gorbunov, Sitthikorn Sitthikankun

NAKHARA (Journal of Environmental Design and Planning)

Urbanization in Thailand has significantly reduced natural infiltration surfaces, intensified stormwater runoff, and increased the demand for effective urban drainage solutions. Bioretention systems, guided by water-sensitive urban design (WSUD) principles, offer a promising approach for enhancing infiltration and mitigating urban flooding. However, the effectiveness of bioretention depends critically on the accurate estimation of saturated hydraulic conductivity (Ks), a key input parameter in hydrological models such as the Storm Water Management Model (SWMM). Despite international guidelines, local Ks values for tropical soils and vegetation remain scarce, limiting model reliability. This study aims to determine its suitability as a filter media layer …

A Cross-Sectional Survey Of Caregiver Knowledge, Attitudes, And Practices Related To Interoception And Feeding Responses Among Children With Adhd, Paige Mehlberg

Health and Nutritional Sciences Graduate Students Plan B Capstone Projects

Background: Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disability that impacts attention, impulse control, and self-regulation, which may also influence eating behaviors and nutrition status. Children with ADHD are more likely to experience feeding challenges, including selective eating, inconsistent appetite, emotional eating, and difficulty recognizing hunger and fullness cues. These challenges may be partially explained by deficits in interoception, or the ability to perceive internal body signals. Caregivers play a key role in shaping feeding behaviors. However, limited research has examined caregiver knowledge and practices related to interoception in this population. 
Objective: To examine caregiver knowledge, attitudes, and practices related …

Effectiveness Of A Six-Week Nutrition And Cooking Education Program On Nutrition Knowledge And Cooking Skills In Unhoused Families, Lucy Mehlhaff

Health and Nutritional Sciences Graduate Students Plan B Capstone Projects

Objective: establish a nutrition and cooking education program at a transitional housing facility in Sioux Falls, SD and evaluate its effect on both nutrition knowledge and cooking skills in participants.
Methods: Using the nutrition education curriculum “Families Eating Smart and Moving More” (FESMM), we conducted a 6-week nutrition and cooking education program at the transitional housing facility, Bishop Dudley Center for Families (BDCFF), in Sioux Falls, South Dakota. Participants attended didactic sessions led by a master’s student in nutrition and dietetics that encouraged healthy and cost-effective eating, as well as took part in hands on cooking lessons with assistance from …

Parental Knowledge, Attitudes, And Practices Related To Interoception And Feeding Behaviors In Children With Adhd: A Cross-Sectional Survey, Hayleigh Young

Health and Nutritional Sciences Graduate Students Plan B Capstone Projects

Objective: Children with attention-deficit/hyperactivity disorder (ADHD) often experience challenges related to interoceptive awareness, which can impact feeding behaviors and overall nutrition. Parents play a critical role in supporting the development of these skills, however limited research has examined parental knowledge and practices related to interoception and child feeding behaviors. Therefore, this study aimed to examine the association between parental knowledge, attitudes, and practices related to interoception and child feeding behaviors in children with ADHD to help inform the development of parent-focused educational resources.
Methods: A cross-sectional survey was developed based on a targeted review of literature examining ADHD, interoception, and …

Flow Injection Determination Of Fluoride For Total Organic Fluorine Analysis, Memona Zulafiqar

Chemistry & Biochemistry Theses

Poly- and perfluoroalkyl substances (PFAS) are anthropogenic chemicals that have gained increasing attention due to their association with a wide range of adverse health effects. These compounds are highly diverse, with approximately 15,000 PFAS reported. Their exceptional environmental stability and strong tendency to bioaccumulate result in environmentally relevant concentrations that typically occur at very low levels, often in the ng L⁻¹ range. This chemical diversity presents a major analytical challenge, as reference standards are available for only a limited number of PFAS. Consequently, conventional targeted analytical methods frequently quantify less than 1% of the total PFAS present, leading to a …

Liutex - A Fluid Vortex, Oscar Alvarez

Mathematics Dissertations

Fluid vortices are found everywhere in our universe. A vortex can take the form of almost anything - from the classical spiral vortex to chaotic plumes. Defining a vortex physically and mathematically is absolutely necessary if we desire to study vortices and their interactions with each other as well as our physical world. Fluid vortices are incredibly important in the study of turbulent flows. From determining wear, optimizing design for better flow, efficiency, etc., to even predicting the weather on Earth or other planets, having the ability to measure vortices in fluid flow is invaluable. In this study, I investigate …

Black Americans' Interactions With Law Enforcement: The Black Church's Response, Shalanda Ehiozee

Doctor of Ministry

This research interrogates the disproportionate frequency of lethal law enforcement encounters involving Black Americans, contextualizing these fatalities within the systemic racial hierarchies foundational to the United States. By tracing the historical evolution of policing from antebellum slave patrols to contemporary practice, this study contends that modern law enforcement serves as a sophisticated mechanism of racial and social control.

To examine this phenomenon, the research employs a qualitative, multidimensional methodology that synthesizes Comparative Caste Analysis, case study examination, and a Christological framework. This inquiry is further bolstered by a longitudinal analysis of African American ecclesiological activism, culminating in a theological reflection …

Sanctioned By God, Opposed By Man: The Denial Of The Homiletic Practice Of Women In The Pulpit By The Madison County Baptist Association Of Churches, Linda Johnson Dunigan

Doctor of Ministry

The ongoing resistance to women’s full participation in church leadership, rooted in biblical and cultural interpretations, continues to marginalize women and uphold systemic inequality within the body of Christ. The debate over women’s preaching and ordination, shaped by differing biblical and cultural understandings, illustrates the complexity of the issue. This study examines the theological and ecclesiastical conflicts surrounding the Madison County Baptist Association of Churches’ (MCBA) prohibition on women’s homiletical practice in the pulpit, citing restrictive interpretations of texts such as 1 Timothy 2:11-15 and 1 Corinthians 14:34-35.

This study aims to demonstrate that opposition to women preaching is shaped …

The Emmaus Conversation: A Cohort Model For Building Bridges Between Lgbtq+ Lived Experience And Church Leadership, Jon Ciccarelli

Doctor of Ministry

Need Problem Opportunity (NPO) Statement

Adventism fosters a harmful culture for LGBTQ+ individuals who want to grow as beloved disciples of Jesus.

Key Insights from Research

• Religious trauma greatly impacts LGBTQ+ individuals.
• Adventism is not pursuing the inclusion of LGBTQ+ individuals.
• The Adventist Church is not benefiting from the fruit of the Spirit experienced and expressed through Adventist LGBTQ+ individuals as part of the body of Christ.
• Empathy, reconciliation, and healing were experienced during the project's prototyping.
• Many Southeastern California Conference pastors and leaders want to grow and engage in this area and be proactive in including LGBTQ+ individuals in …

Turn On The Light Of Life(Tll) Pastoral Theology For Integrated Mental And Spiritual Health In The Ethiopian Orthodox Tewahedo Church Perspective, Leulekal Akalu Alemu

Doctor of Ministry

This study explores a unified framework for integrating mental health counseling with spiritual guidance within the Ethiopian Orthodox Tewahedo Church pastoral theology, emphasizing the essential role of clergy in promoting both spiritual and mental well-being. The initiative aims to establish a structured approach that aligns mental health strategies with theological principles, thereby enhancing the connection between mental wellness and spiritual vitality.

Current observations indicate that many clergy members lack adequate training in pastoral counseling, which significantly impedes their ability to effectively address the mental and social issues faced by their communities. This research seeks to empower church leaders by providing …

Betrothed To Jesus: Embracing Uncertainty As The Key To A Lasting Romance, Kyle H. Chase

Doctor of Ministry

NPO:

Churches are not giving college students the tools they need to navigate uncertainty with Jesus.

Key Insights:

For college students who decide to follow Jesus, the experience of uncertainty after college can result in a deconstruction of faith. Church leaders often respond by equipping students with tools aimed at eradicating uncertainty (biblical and cultural apologetics, catechisms, formulaic practices, etc.). The solution is more elegant: If students are to remain adaptable and resilient for a lifetime, they do not need to eradicate uncertainty but to embrace it—not as an occasion for explanation but as an opportunity to encounter the living …

Re-Imagining Church As A Spiritual Family, Abraham Acosta-Newball

Doctor of Ministry

The contemporary Christian church faces a crisis of belonging; many members are opting out for non-theologically related reasons or differences. The claim for this exodus is a lack of genuine community that serves as an extended spiritual family. Modern churches function as event-centered gatherings, and less like a multigenerational community, reflecting instead a culture of individualism and spiritual consumerism. The purpose of this project is to explore strategies for churches to assume a more biblical role of a spiritual family. Particularly focusing on practical ways for building stronger community within multigenerational and multiethnic Worship settings. The project culminates in three …

Ai-Powered Lawyering: Ai Reasoning Models, Retrieval Augmented Generation, And The Future Of Legal Practice, Daniel Benjamin Schwarcz, Sam Manning, J.J. Prescott, Patrick Barry, David R. Cleveland, Beverly Rich

Articles

Generative AI is set to transform the legal profession, though its most promising uses and ultimate effects are still unclear. While AI models like GPT-4 improve efficiency, they can also “hallucinate” and may undermine legal judgment, particularly in complex tasks typically handled by skilled lawyers. This article examines two emerging AI innovations that may mitigate these concerns: Retrieval Augmented Generation (RAG), which grounds AI-powered analysis in legal sources, and AI reasoning models, which structure complex reasoning before generating output. We conduct the first randomized controlled trial assessing these technologies, assigning upper-level law students to complete legal tasks using a RAG-powered …

Grading Machines: Can Ai Exam-Grading Replace Law Professors?, Kevin L. Cope, Jens Frankenreiter, Scott Hirst, Eric A. Posner, Daniel Schwarcz, Dane Thorley

Articles

In the past few years, large language models (LLMs) have achieved significant technical advances, enabling legal-advocacy organizations to adopt them as complements to—or substitutes for—lawyers and other human experts. The role of LLMs in legal education, however, is underexplored. While several studies have examined LLMs’ performance in taking law school exams, finding mixed results, there have been no published studies systematically analyzing LLMs’ competence at one of law professors’ chief responsibilities: grading law school exams. This paper presents results of an analysis of how LLMs perform in evaluating student responses to legal analysis questions of the kind typically contained in …

Assessing Interdisciplinary Learning And Knowledge: A State-Of-The-Art Review And Heuristic, Kacey Beddoes, Kristi Bartlett

Product Design Faculty Publications

Background – The need for interdisciplinary training is increasingly important, but assessing the effects of interdisciplinary education initiatives remains challenging. One of the leading difficulties is identifying and selecting the best instrument or technique for a given purpose.

Purpose -- To help researchers and educators identify available options and determine the best options for their purposes, we conducted a literature review and created a heuristic table of available techniques. Our review addresses the questions: 1) What domain-general techniques and instruments exist for assessing interdisciplinary learning or knowledge? 2) What research scenarios, populations, and questions are each technique or instrument most …

The Transport Of New Make Spirits Through American White Oak, Taylor E. Scott, Jarrad Gollihue, Michael P. Sama, Michael Shaffer, Brad J. Berron

Biosystems and Agricultural Engineering Faculty Publications

Why was the work done: The reduction of maturation loss is a significant opportunity for increased revenue in aged spirits and varies through several factors. This work aims to better understand maturation loss by isolating and measuring spirit flow through wood.

How was the work done: Bourbon stave disks were fabricated by computer numeric control milling and loaded into a sealed module consisting of flanges holding the stave disk over a liquid filled pipe. The modules were filled with new make spirit at 50, 62.5 or 70% ABV, with either liquid or vapour contact with the stave disk. Further, the …

The First Resurrection, James M. Taylor

Heritage Material

No abstract provided.

Nevada_Raw_Data_06.02.2026_2, Yasha Kahn, Lori Nichols, Panduka Nagahawatte

Nevada

No abstract provided.

How To Manage The Wolf In The Fold, Susan Bisom-Rapp, Urwana Coiquaud

Faculty Scholarship

Recent scholarly work on regulatory capture in the platform economy accounts for the political role and power wielded by app-based firms aiming to reform the existing legal environment to favor their low-cost labor business models. This article adds to scholarly perspectives on the platform economy by shifting the focus to government actors, the role of narrative in communicating with the public, and institutional constraints which may hamper the government’s ability to provide a cogent rationale for opposing or implementing legal change. The article’s central contribution is underscoring the role the government plays in facilitating or preventing regulatory capture. To that …

Discursive Footnotes, Daniel Yeager

Faculty Scholarship

This essay offers a comprehensive account of the past forty years of scholarship on footnotes within law. Not just any old footnotes, but footnotes that are discursive in form, that is, those with an expressive rather than bibliographic function. After contrasting the function of discursive footnotes in judicial opinions with those in academic legal literature, this essay identifies and decodes a comparatively hidden avant garde footnotes literature. Borrowing from techniques of literary criticism, that literature, properly understood, provides a foundation for our making more subtle judgments about both the relation of primary to secondary texts and the allocation of responsibilities …

Expanding The Good Samaritan Program: Cleaning Up The Colorado River, One Mine At A Time, Jordan Carlson

Wyoming Law Review

The headwaters of the Colorado River Basin supply nearly 90% of the river’s flow and are among the most hydrologically sensitive areas in the U.S. During the nineteenth and early twentieth centuries, westward expansion and the allure of gold and other valuable minerals drove thousands of miners into the basin. When the mining boom ended, the mines were left behind. Today, thousands of abandoned hardrock mine sites continue to leach acidity and heavy metals into streams, leaving a lasting impact on water quality. For decades, strict environmental liability laws made cleanup nearly impossible, creating a chilling effect that discouraged even …

Full Issue, Wyoming Law Review Editorial Board

Wyoming Law Review

No abstract provided.