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Articles 100591 - 100620 of 5153638
Full-Text Articles in Entire DC Network
Using Side Looking Hydroacoustics And Community Size Spectra To Assess Invasive Carp’S Impact On Fish Assemblage Integrity, Daniel Jacob Bryan
Using Side Looking Hydroacoustics And Community Size Spectra To Assess Invasive Carp’S Impact On Fish Assemblage Integrity, Daniel Jacob Bryan
Graduate Theses, Dissertations, and Problem Reports (ETD)
Often accounting for over half of total fish biomass, invasive silver carp have dramatically reshaped the ecosystem of the Mississippi River and its tributaries. These high silver carp densities have been shown to affect native fish body condition, abundance, and community structure, highlighting the need for efficient methods to quantify silver carp’s effect on the native fish assemblage. Community size spectra (CSS) is a metric that quantifies fish assemblage body size structure based on the decrease in fish abundance with increasing size. To estimate silver carp’s effects on CSS in the Ohio River, side looking hydroacoustic monitoring was used alongside …
Utilizing Plethodontid Occupancy To Assess Initial Ecosystem Responses To Invasive Plant Control Treatment In The Central Hardwoods, Maree Guinevere Dieterich
Utilizing Plethodontid Occupancy To Assess Initial Ecosystem Responses To Invasive Plant Control Treatment In The Central Hardwoods, Maree Guinevere Dieterich
Graduate Theses, Dissertations, and Problem Reports (ETD)
Invasive plants are a growing concern for land managers, impacting ecosystem resilience and outcompeting native vegetation. To combat this, invasive plant control treatments can assist in reducing the impacts and spread of damaging, non-native plant species. However, intensive treatments completed at large scales have the potential to negatively impact ecosystem services as well. To monitor these impacts, I utilized a well-known indicator in the Central Applachian region, Plethodontid salamanders, to assess impacts of invasive plant control treatments in the Central Hardwood forests. I completed 12 visual samples across 60 sites in West Virginia, USA during Spring and Fall of 2025 …
Graded Repertoire For Violin By Latin American Composers: Pedagogical Analysis And Categorization Of Selected Pieces, Irene Guerra Rudas
Graded Repertoire For Violin By Latin American Composers: Pedagogical Analysis And Categorization Of Selected Pieces, Irene Guerra Rudas
Graduate Theses, Dissertations, and Problem Reports (ETD)
Repertoire sequences have evolved from a collection of technical studies into a comprehensive educational framework. This research aims to enhance the integration of innovative pedagogical materials by identifying, analyzing, and categorizing works originally composed for violin by Latin American composers. These works are assessed for their suitability within a structured violin curriculum and organized into graded levels, ranging from elementary to advanced.
Each selected piece is evaluated according to pedagogical parameters commonly used in established violin teaching traditions. These parameters include pitch range, rhythmic complexity, bow strokes, length, stylistic diversity, musical language, and the historical and cultural relevance of both …
Student And Teacher Perceptions Of Confirming Behaviors Across Instructional Modalities, April Nicole Wright
Student And Teacher Perceptions Of Confirming Behaviors Across Instructional Modalities, April Nicole Wright
Graduate Theses, Dissertations, and Problem Reports (ETD)
This dissertation examined how undergraduate students and instructors evaluate lowinference teacher confirmation behaviors across instructional modalities and identified additional behaviors perceived as confirming in contemporary instructional contexts. Participants included 274 undergraduate students and 104 higher-education instructors who completed a survey measuring four clusters of confirming behaviors (willingness to engage, recognition, acknowledgment, and endorsement) using a 7-point Likert-type scale. Open-ended questions invited participants to describe confirming behaviors not represented in existing measures. Results indicated that both students and instructors rated most behaviors above the midpoint of the scale, with instructional responsiveness and course organization receiving the highest ratings. Instructors rated all …
Teaching Evolution After Kennedy And Mahmoud, Alexander Gouzoules
Teaching Evolution After Kennedy And Mahmoud, Alexander Gouzoules
Faculty Publications
One of the longest running disputes at the intersection of education law and the First Amendment has involved conflict over evolutionary biology in American public schools. Through a century of nearly continuous litigation, creationist legislation and parental demands to exempt students from science instruction have been constrained by longstanding First Amendment doctrines.
That settlement is now unraveling. In Kennedy v. Bremerton School District, the Supreme Court abandoned its prior approach to the Establishment Clause in favor of a history-and-tradition analysis that is ill-suited to questions about modern scientific education. And in Mahmoud v. Taylor, the Court held that students' compulsory …
Shock-Wave Structure In A Monatomic Gas Mixture With Rydberg Atoms, Anna Markhotok
Shock-Wave Structure In A Monatomic Gas Mixture With Rydberg Atoms, Anna Markhotok
Physics Faculty Publications
The effect of atom size on the shock-wave structure in a binary monatomic gas mixture with Rydberg atoms has been investigated. The problem was solved numerically using the system of hydrodynamic equations in argon gas for the atom-size ratios between 2 and 100, T = 1500 K, and the density between 10¹⁷ and 10²⁰ m−³. It was found that the presence of larger-sized atoms in the mixture results in shock front splitting that is on the order of the mean free path for this component. The results could be of interest in supersonic plasma dynamics and in astrophysics, studying shock …
Intersectionality In Discrimination, Posttraumatic Stress Symptoms, And Suicide Ideation: Black Americans In Appalachian Contexts, Jailyn May Wilson
Intersectionality In Discrimination, Posttraumatic Stress Symptoms, And Suicide Ideation: Black Americans In Appalachian Contexts, Jailyn May Wilson
Graduate Theses, Dissertations, and Problem Reports (ETD)
Racial discrimination is recognized as a race-based traumatic stressor that has been associated with posttraumatic stress symptoms (PTSS) and suicide ideation (SI). However, there remains a paucity of research investigating the impact of racial and other forms of discrimination on understudied populations, including Black Americans residing in Appalachian regions. The current study used an online self-report survey to examine PTSS as a mediator in the association between perceived discrimination and SI and to examine the moderating effect of the number of identity factors with which one experienced discrimination (i.e., race, gender, region) on the relationship between perceived discrimination and PTSS. …
Conocimiento, Formación Y Autoeficacia De Los Docentes Regulares En El Manejo De La Autorregulación Emocional De Estudiantes Con Trastorno Del Espectro Autista, Yalinette Negrín Carrión
Conocimiento, Formación Y Autoeficacia De Los Docentes Regulares En El Manejo De La Autorregulación Emocional De Estudiantes Con Trastorno Del Espectro Autista, Yalinette Negrín Carrión
Theses and Dissertations
El propósito de esta investigación fue analizar el nivel de conocimiento, la formación profesional y la autoeficacia de los docentes regulares de la escuela elemental, así como examinar las relaciones existentes entre estos factores y la implementación de estrategias de intervención educativa orientadas a la autorregulación emocional en estudiantes con Trastorno del Espectro Autista (TEA). El presente estudio adoptó un enfoque cuantitativo con un diseño no experimental, de tipo transeccional descriptivo-correlacional. Este diseño permitió describir las características de los fenómenos educativos y analizar las relaciones existentes entre variables sin manipularlas. Las variables del estudio fueron el conocimiento docente sobre el …
Competencias Digitales Y Actitudes Hacia La Tecnología Como Factores En La Integración De Recursos Digitales En El Aula Por Docentes De Nivel Elemental, Yaritzabel Jiménez Rosa
Competencias Digitales Y Actitudes Hacia La Tecnología Como Factores En La Integración De Recursos Digitales En El Aula Por Docentes De Nivel Elemental, Yaritzabel Jiménez Rosa
Theses and Dissertations
Esta disertación aplicada examinó en qué medida las competencias digitales y las actitudes hacia la tecnología influyeron en la integración de recursos digitales en el aula por parte de docentes de escuelas públicas elementales de la Región Educativa de Mayagüez, Puerto Rico. El estudio empleó un diseño no experimental de corte transversal, enmarcado en un enfoque cuantitativo comparativo. La muestra estuvo compuesta por 55 docentes de cuatro escuelas públicas elementales de un municipio de dicha región educativa. Para la recopilación de datos se utilizó un cuestionario estructurado con ítems tipo Likert, dirigido a medir competencias digitales, actitudes hacia la tecnología …
Investigation Expenses, Ryan Vacca
Investigation Expenses, Ryan Vacca
Faculty Publications
Misappropriating trade secrets is usually done in secret. After all, those taking another’s trade secret in violation of state and federal law rarely openly tout their misdeeds. As a result, trade secret owners do not always immediately realize that their trade secret has been misappropriated and must spend significant resources investigating whether misappropriation has occurred and, if so, by whom and to what extent.
An important question frequently arising over the last several years but overlooked in the scholarly literature is whether a trade secret owner’s investigation expenses are recoverable as “actual loss” under state and federal trade secret laws. …
Artificial Intelligence, Judicial Evolution, And Insurance, Renee Henson
Artificial Intelligence, Judicial Evolution, And Insurance, Renee Henson
Faculty Publications
AI-driven platforms have the potential to inflict traditional injuries in new ways. Proprietary algorithms trained on large volumes of personal data can cause mental, emotional, and sometimes physical injuries via conversational exchanges, harmful content recommendations, and the promotion of extremist content. This "algorithmic liability" fundamentally challenges existing legal doctrines and statutory protections, thereby exposing deficiencies in current insurance coverage frameworks.
Historically, courts dismissed algorithmic liability claims early in litigation, invoking Section 230 immunity and First Amendment protections, and resisted classifying algorithmic tools as "products" for the purposes of products liability law. Recent jurisprudence, however, signals a critical turning point. On …
Planes De Sucesión En Los Hospitales De La Región Metro De Puerto Rico, Eddie Correa Medina
Planes De Sucesión En Los Hospitales De La Región Metro De Puerto Rico, Eddie Correa Medina
Theses and Dissertations
Esta disertación aplicada ha sido diseñada con el propósito de conocer las percepciones, experiencias, vivencias y conocimientos de los líderes y gerentes en enfermería sobre la implementación de los planes de sucesión en los hospitales del área metropolitana de Puerto Rico. La utilidad de esta investigación parte del argumento que tienen estos planes para mejorar la retención de empleados, facilitar la transferencia de conocimientos, evitar la rotación excesiva en puestos críticos, entre otros elementos. En el primer capítulo se presentó la introducción de la disertación, lo que incluyó aspectos como el propósito, objetivos, audiencia, rol del investigador, contribuciones al campo …
A Front-End Analysis Of Teacher Retention At A High Poverty K-5 Public School, Nicole Gray
A Front-End Analysis Of Teacher Retention At A High Poverty K-5 Public School, Nicole Gray
Theses and Dissertations
This dissertation explored the experiences of educators impacted by teacher retention issues at a high-poverty K-5 public school. Researchers have studied the decline in individuals entering into the education profession as well as the high rates of individuals exiting the profession. With individuals leaving the profession at high rates, and not enough entering to replace those that are leaving, there is now a massive shortage with not enough teachers to meet the needs of students in public schools. The few individuals that are entering into the profession are not being retained, especially at high-poverty schools. This study explored the thoughts …
Experimental And Computational Investigation Of Defect-Tolerant Pnictide Semiconductors, Gideon Belay Kassa
Experimental And Computational Investigation Of Defect-Tolerant Pnictide Semiconductors, Gideon Belay Kassa
Dartmouth College Ph.D Dissertations
The discovery of new photovoltaic semiconductors is challenging because performance depends on the simultaneous optimization of band gap, optical absorption, carrier lifetime, and defect tolerance. We address this challenge through an experiment-theory feedback loop, testing a promising group of pnictide semiconductors identified through high-throughput computational screening. Our experimental results provide more insights to further improve the theoretical screening process. We present an investigation of the optoelectronic properties of the Zintl pnictide BaCd2P2 (BCP), showing that it exhibits bright band-to-band photoluminescence emission, strong photoconductive-current generation, a room-temperature carrier lifetime of up to 300 ns, and an implied open-circuit voltage comparable to …
The Structure, Dynamics, And Impact Of An Interbacterial Weapon Encoded By Human Gut Bacteria, Casey John Latario
The Structure, Dynamics, And Impact Of An Interbacterial Weapon Encoded By Human Gut Bacteria, Casey John Latario
Dartmouth College Ph.D Dissertations
The human gut is densely colonized by diverse bacteria. Over a human’s growth, the GI tract becomes a dynamic community that is subjected to a continual in-flow of nutrients and would-be colonizers and an out-flow of microbes and waste products. Despite these dynamics, the bacterial community often displays stability, with particular strains persisting over decades. These stable colonizers have evolved mechanisms to bolster their colonization, resist disruption by other microbes, and persist through environmental flux.
Both interbacterial competition and horizontal gene transfer (HGT) contribute to colonization and survival within the GI tract. A major mechanism for interbacterial competition is the …
Deep Learning Assisted Time-Resolved Optical Imaging For Surgical Guidance And Radiotherapy, Shiru Wang
Deep Learning Assisted Time-Resolved Optical Imaging For Surgical Guidance And Radiotherapy, Shiru Wang
Dartmouth College Ph.D Dissertations
Image-guided therapy enables clinicians to monitor treatment progress, verify accurate delivery, and make immediate adjustments. Among various imaging modalities available for this purpose, optical imaging techniques offer distinct advantages for real-time guidance through their non-ionizing nature and high temporal resolution. However, light propagation in biological tissue fundamentally limits these imaging modalities by obscuring spatial information and introducing noise artifacts. These physical constraints make it hard to accurately interpret subsurface structures and compromise the reliability of real-time guidance.
This thesis develops deep learning methods to overcome these limitations in two distinct optical imaging modalities. The first approach aims to improve time-of-flight …
Cross-Temporal Statistical Approaches For Evaluating Predictor-Outcome Relationships, Jeff Joseph
Cross-Temporal Statistical Approaches For Evaluating Predictor-Outcome Relationships, Jeff Joseph
Dartmouth College Ph.D Dissertations
Central auditory function is linked with cognitive deficits, but few research projects use existing statistical approaches or develop new ones to forecast cognitive deficits using the results of central auditory tests. To address this limitation, we use a series of statistical learning frameworks for predicting a child’s cognitive abilities based on his/her central auditory performances and demographic factors. Two key challenges exist. First, children may start the study at a time when they are unable to perform the central auditory tests or cognitive tests. Second, cognitive performance is age-dependent, particularly in the early formative years of childhood and adolescence. To …
Black Ecological Care: Conservation, Environmental Justice, And Sovereignty In Baltimore, Maryland, Alexandria Nicole Casteel
Black Ecological Care: Conservation, Environmental Justice, And Sovereignty In Baltimore, Maryland, Alexandria Nicole Casteel
Dartmouth College Ph.D Dissertations
Dominant traditions of urban planning, municipal policy, and environmental science register Black urban spaces through a vocabulary of pathology, as sites of ecological deficit, contamination, and social decay. This dissertation investigates how Black communities in U.S. cities attend to the environment in ways that address legacies of environmental and social injustice while opening pathways toward different environmental futures. I gather these practices under the analytic of Black ecological care, which captures the generative labor of making and maintaining livable worlds within, alongside, and beyond histories of harm. I develop the analytic across twenty-nine months of ethnographic fieldwork in 2021 and …
Ice Stream Formation, Activation, And Evolution, Logan E. Mann
Ice Stream Formation, Activation, And Evolution, Logan E. Mann
Dartmouth College Ph.D Dissertations
While the Greenland and Antarctic ice sheets deform as slow viscous fluids, ice streams are regions of ice that flow several orders of magnitude faster than the surrounding ice ridges. Ice streams form the primary drainage networks for ice sheets and are currently responsible for the majority of discharge from the West Antarctic Ice Sheet. Many catchments like the Siple Coast of West Antarctica display a complex array of flow morphologies that are not primarily determined by bed topography. Instead, flow is primarily governed by thermal conditions along the bed and in shear margins that lead to rapid till deformation. …
The Influence Of Metacognition On College Readiness And Persistence, Michael L. Fitzgerald
The Influence Of Metacognition On College Readiness And Persistence, Michael L. Fitzgerald
Theses and Dissertations
This applied dissertation examined the influence that metacognition has on college readiness and its most traditionally used metrics: performance-based outcomes and persistence. Specifically, this study addressed to what degree underlying metacognitive structures differ between college students’ successful metrics of performance and persistence compared to a more general sample of college students.
The research characterized metacognition along three domains of analysis: (a) selfefficacy/ motivation, (b) soft skills/psychological capital (Psycap), and (c) expected value of control (EVC). The quantitative study included 54 college students and a crosssectional design. Participants completed a four-part Likert-style survey, where their responses were measured along the three …
Análisis De La Relación Entre Las Competencias Digitales Y El Rendimiento Académico En Estudiantes De La Carrera De Educación En Un Centro Universitario De La Región Este De La República Dominicana, Ángel Erich Cedano Cabrera
Análisis De La Relación Entre Las Competencias Digitales Y El Rendimiento Académico En Estudiantes De La Carrera De Educación En Un Centro Universitario De La Región Este De La República Dominicana, Ángel Erich Cedano Cabrera
Theses and Dissertations
Esta disertación aplicada examinó la relación entre las competencias digitales y el rendimiento académico en la formación docente de la República Dominicana. El estudio abordó la escasez de evidencia empírica en el Centro Universitario de la Región Este, situación que limita el desarrollo de políticas educativas y estrategias pedagógicas fundamentadas en datos locales.
Se empleó un diseño cuantitativo, no experimental, correlacional y transeccional con una muestra de 120 estudiantes de las menciones en Educación Básica, Inicial y Física. Los datos se recolectaron mediante el Cuestionario para el estudio de la Competencia Digital del Alumnado de Educación Superior (CDAES) y los …
Higher-Level Questioning In Elementary English Language Arts, Charity Zawatski
Higher-Level Questioning In Elementary English Language Arts, Charity Zawatski
Theses and Dissertations
This exploratory case study addressed the difficulty with higher-level metacognition and questioning in a primary level elementary English Language Arts. This case study was determined as a need based on underperforming scores from the state assessment in ELA.
The research method look at the social phenomenon through inquiry around the rigor in higher-level questioning and the use of hand signals to support connections in learning. The researcher applied a semi-structured interview, an observation checklist, and a random sample of student artifacts as instruments for data collection. The researcher analyzed teachers’ lesson plans for a unit, observed a virtual classroom lesson …
Does Integrating Parental Involvement In Therapy Improve Behavior In Children With Attention Deficit Hyperactivity Disorder?, Pamela Lassiter
Does Integrating Parental Involvement In Therapy Improve Behavior In Children With Attention Deficit Hyperactivity Disorder?, Pamela Lassiter
Theses and Dissertations
The research problem was the lower success rate of interventions for children with attention deficit hyperactivity disorder (ADHD) because of the exclusion of parents in the counseling process. The purpose of the research was to explore if integrating parent involvement in therapy improved the behaviors in children with ADHD. The study occurred at a private mental health facility that used cognitive behavior therapy and behavior interventions with the children.
The study was guided by the phenomenological qualitative research design. Ten single parents of male children, ages 4 to 10 with ADHD, participated in this study. Parents were selected using a …
Measuring Value-In-Use Management From The Supplier's Perspective, Amit Mahimkar, John Hadjimarcou, Edward Ramirez
Measuring Value-In-Use Management From The Supplier's Perspective, Amit Mahimkar, John Hadjimarcou, Edward Ramirez
Faculty Publications – Marketing
Business-to-business (B2B) marketing is increasingly shifting from transactional exchanges to the long-term management of customer relationships. As suppliers offer complex, integrated solutions, the focus has shifted from product attributes to the value realized during usage. To manage this experienced value-in-use (VIU), suppliers are establishing organizational structures and processes dedicated to VIU management (VIUM). Despite its growing theoretical and managerial significance, no validated instrument currently exists to assess VIUM implementation from the supplier's perspective. This study develops and validates a second-order formative supplier-side index comprising seven VIUM subprocesses. Nomological evidence (based on survey data from B2B supplier managers, N = 284) …
Effect Of Graphene Oxide On The Upconversion Photoluminescence Behavior Of Er/Yb Co-Doped Pvdf-Go Composite Nanofibers, Saptasree Bose, Jack Ryan Summers, Bhupendra B. Srivastava, Karen Lozano, Victoria Padilla-Gainza
Effect Of Graphene Oxide On The Upconversion Photoluminescence Behavior Of Er/Yb Co-Doped Pvdf-Go Composite Nanofibers, Saptasree Bose, Jack Ryan Summers, Bhupendra B. Srivastava, Karen Lozano, Victoria Padilla-Gainza
Mechanical Engineering Faculty Publications
Upconversion photoluminescence (UCPL) materials, particularly rare-earth (RE) doped nanoparticles, have garnered significant attention due to their ability to convert near-infrared (NIR) excitation into visible emission, offering benefits such as high photostability, long lifetimes, low autofluorescence, and deep tissue penetration. Among various platforms, polymer-based one-dimensional (1D) nanofibers with in-situ lanthanide doping remain relatively unexplored, despite their superior mechanical flexibility, processability, and potential for improved luminescence performance. In this study, we report the fabrication and UCPL quenching behavior of Er3+/Yb3+ co-doped polyvinylidene difluoride (PVDF) nanofibers incorporated with graphene oxide (GO), synthesized for the first time using the scalable Forcespinning® technique. PVDF, a …
Journal Of Dental Sciences Editorial Board
Journal Of Dental Sciences Editorial Board
Journal of Dental Sciences
No abstract provided.
Dental Treatment And Oral Care For Patients With Severe Mental Illness Receiving Psychiatric Home-Visit Care: A Narrative Review With An Illustrative Case, Takayuki Suga, Trang Thi Huyen Tu, Yuji Gamo, Takafumi Asakura, Shigeru Iida, Akira Toyofuku
Dental Treatment And Oral Care For Patients With Severe Mental Illness Receiving Psychiatric Home-Visit Care: A Narrative Review With An Illustrative Case, Takayuki Suga, Trang Thi Huyen Tu, Yuji Gamo, Takafumi Asakura, Shigeru Iida, Akira Toyofuku
Journal of Dental Sciences
Patients with severe mental illness (SMI) often have untreated caries, periodontal inflammation, tooth loss, xerostomia-related risk, dental anxiety, and delayed dental attendance. This narrative review aimed to synthesize evidence relevant to dental treatment planning for patients with SMI receiving psychiatric home-visit care and to clarify when domiciliary dental assessment and repeated professional oral care may be indicated. Targeted literature searches and citation tracking were used to identify reviews, epidemiological studies, intervention studies, qualitative syntheses, and special care dentistry guidance. The evidence indicates that oral disease in SMI reflects not only limited knowledge but also avolition, cognitive impairment, psychosis, sedation, medication-induced …
Evaluation Of Condylar Position Displacement Using Various Centric Relation Recording Techniques Based On Maximum Intercuspation Position: A Systematic Review And Meta-Analysis, Ling-Shiuan Huang, Yen-Chang Huang, I-Ting Wu, Shinn-Jyh Ding
Evaluation Of Condylar Position Displacement Using Various Centric Relation Recording Techniques Based On Maximum Intercuspation Position: A Systematic Review And Meta-Analysis, Ling-Shiuan Huang, Yen-Chang Huang, I-Ting Wu, Shinn-Jyh Ding
Journal of Dental Sciences
Background/ purpose: Restoring tooth defects is a key clinical task for dentists, aimed at either maintaining or reconstructing a functional occlusal dentition. This study conducted a systematic review and meta-analysis of clinical trials comparing centric relation (CR) and maximum intercuspal position (MIP) condylar positions obtained using various CR techniques, and to verify the reproducibility of these methods.
Materials and methods: The PubMed, Embase, Google Scholar, and Cochrane Library databases were searched for articles published before January 2026. The single-arm meta-analysis used a random-effects model to calculate the overall effect size.
Results: This study included 12 articles published …
Efficacy Of Cryotherapy For Oral Leukoplakia: A Systematic Review, Chuan-Hang Yu, Tzu-Chen Chan, Chun-Pin Chiang
Efficacy Of Cryotherapy For Oral Leukoplakia: A Systematic Review, Chuan-Hang Yu, Tzu-Chen Chan, Chun-Pin Chiang
Journal of Dental Sciences
Oral leukoplakia (OL) is the most common oral potentially malignant disorder and carries a risk of malignant transformation. Cryotherapy is a minimally invasive treatment option for OL, but its efficacy and optimal dose-response remain inconsistent among various studies. This systematic review evaluated the clinical efficacy and safety of cryotherapy for OL lesions and explored whether the characteristics of the lesions and treatment parameters influenced clinical outcomes. Electronic searches were performed in Embase, PubMed, and the Cochrane Central Register of Controlled Trials according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Seven studies reporting original clinical outcomes of …
Epigallocatechin Gallate In Dentistry: Therapeutic Applications, Biomaterial Integration, And Translational Challenges, Chloe Jui-Yun Chang, Fang-Yu Fan, Yung-Li Wang, Thi Thuy Tien Vo, Yang-Che Wu, Yu-Chia Chang, I-Ta Lee
Epigallocatechin Gallate In Dentistry: Therapeutic Applications, Biomaterial Integration, And Translational Challenges, Chloe Jui-Yun Chang, Fang-Yu Fan, Yung-Li Wang, Thi Thuy Tien Vo, Yang-Che Wu, Yu-Chia Chang, I-Ta Lee
Journal of Dental Sciences
Epigallocatechin gallate (EGCG), a major bioactive catechin in green tea, has attracted increasing attention in dentistry because of its antioxidant, anti-inflammatory, antimicrobial, matrix-modulating, and regenerative properties. This narrative review summarizes current evidence on the biological mechanisms, dental applications, and translational challenges of EGCG in oral healthcare. EGCG can modulate oxidative stress and inflammatory signaling pathways, including nuclear factor-kB (NF-kB), mitogen-activated protein kinase (MAPK), nuclear factor erythroid 2-related factor 2/heme oxygenase-1 (Nrf2/HO-1), and NOD-like receptor family pyrin domain containing 3 (NLRP3)-related responses, and has activity against oral disease-associated microorganisms and biofilms. In periodontal therapy, EGCG has been investigated as an adjunct …