Chemical Engineering Commons^™

Optimizing Polymer Fluorescence For Explosives Detection, Rose K. Cersonsky

Honors Scholar Theses

Pyrene is commonly used for explosives detection, as when mixed with polystyrene, the fluorescence intensity of the resulting film can be used as an indicator of the presence of nitro-aromatic, nitro-ether, or nitro-amine explosives. Previous studieshave tested a three-component system including pyrene, polystyrene, and a salt, tetrabutylammonium hexafluorophosphate (TBAHP). From these previous studies, it has been seen that vapor pressure of the preparation area is a governing factor in the formation of excimers, which are instrumental in achieving and maintaining fluorescence intensity. In this study, three parameters – solution concentration, film thickness, and molecular weight of polystyrene are examined to …

Drug Delivery With Feedback Control In Bioresponsive Hydrogels, Andrew Wilson

All Dissertations

Bioresponsive hydrogels are emerging with technological significance in targeted drug delivery, biosensors and regenerative medicine. The design challenge is to effectively link the conferred biospecificity with an engineered response tailored to the needs of a particular application. Moreover, the fundamental phenomena governing the response must support an appropriate dynamic range, limit of detection and the potential for feedback control. The design of these systems is inherently complicated due to the high interdependency of the governing phenomena that guide sensing, transduction and actuation of the hydrogel. The objective of the dissertation is to review the current state of bioresponsive hydrogel technology …

Water System For Developing Countries / Disaster Relief Made With Local Materials, Keiron Anton Hamilton Durant

Chemical Engineering Undergraduate Honors Theses

My main duty for the project was to design various tests to assess the quality of the water and to assure that the water we were producing complies with the World Health Organization’s standards. I was responsible for researching these requirements and communicating with experts in the field so that our team could make logical decisions as to how the design should be altered. The first professor I had interactions with was Dr. Julian Fairy who is a civil engineering expert in waste water treatment. He advised us on our entire system design and effective ways for testing the chlorine …

Fluorescence Imaging Of Microdialysis Sampling, Jordan Leigh Haynie

Chemical Engineering Undergraduate Honors Theses

Many biomolecules including proteolytic enzymes known as matrix metalloproteinases (MMPs) are released when a material, such as a microdialysis probe, is implanted in a living organism. The MMPs cleave structural protein components of the extracellular matrix and play an important role in biological functions such as wound healing.1-3 Many enzymatic substrates for MMPs have fluorescent product mimics, and the mimics can be used as agents to monitor biochemical processes.1 In this study, microdialysis, a minimally invasive sampling technique, was combined with fluorescence imaging to determine the possibility of monitoring microdialysis in real-time, and thus provide a method that could ultimately …

A Peptoid-Based Targeted Drug Delivery System For The Treatment Of Metastatic Cancer, Hugh M. Purdy

Chemical Engineering Undergraduate Honors Theses

Development of a targeted drug delivery system is a critical step in the effort to improve cancer treatments. Such a system would greatly reduce the harmful side effects of chemotherapy by delivering toxic drugs directly to cancerous cells. Peptoids—synthetic compounds that can be easily produced from readily available amine monomers—have great potential for use in targeted drug delivery. This project aimed to develop peptoids that would bind to specific proteins expressed on the surface of cancer cells. These peptoids could be combined into a complex that would bind to the proteins with an even greater affinity than the individual compounds. …

Coal Fires: An Environmental Disaster, Lidsay Hoggatt

Chemical Engineering Undergraduate Honors Theses

The mission of the Coal Fire Gang (CFG) is to spread awareness about the global issue of uncontrolled coal fires, and to highlight them as a low-hanging fruit of immediate emissions reduction. This report summarizes CFG’s research for the WERC competition, for which this topic was chosen as an open task. Beyond raising awareness, CFG modeled, developed and built an experimentation apparatus meant to prove the validity of a relatively cheap extinguishing method which was also novel to the regions in which it could be employed. The apparatus, which simulated an underground coal fire, was used to test a sand …

Fabrication Of Nanoscale Features On Surfaces, James C. Proctor

Chemical Engineering Undergraduate Honors Theses

A method to form nanofeatures on the surface of a material by utilizing a prefabricated polymer nanostructures is proposed. A means by which the polymer structures can be produced is discussed. The advantages and disadvantages of this process and other nanolithography processes are evaluated.

Coal Fires: An Environmental Disaster, Daniel Robert Miskin

Chemical Engineering Undergraduate Honors Theses

The mission of the Coal Fire Gang (CFG) is to spread awareness about the global issue of uncontrolled coal fires, and to highlight them as a low-hanging fruit of immediate emissions reduction. This report summarizes CFG’s research for the WERC competition, for which this topic was chosen as an open task. Beyond raising awareness, CFG modeled, developed and built an experimentation apparatus meant to prove the validity of a relatively cheap extinguishing method which was also novel to the regions in which it could be employed. The apparatus, which simulated an underground coal fire, was used to test a sand …

Water System For Developing Countries/Disaster Relief Made With Local Materials, Cayla Tichy

Chemical Engineering Undergraduate Honors Theses

The United Nations estimates that water-borne illness accounts for 80% of deaths in developing nations and that nearly 1 in 6 do not have access to clean water (1). However, despite the ability to produce water in the developed world from complex streams such as wastewater or seawater, challenges remain in providing this basic resource in the developing world. Too often the approach has been to apply a high-tech solution, which requires significant technical expertise to run and significant financial resources to repair. Furthermore, as every developing nation faces different challenges, a new solution must be provided for each situation. …

Coal Fires - An Environmental Disaster, Nicholas Kordsmeier

Chemical Engineering Undergraduate Honors Theses

The mission of the Coal Fire Gang (CFG) is to spread awareness about the global issue of uncontrolled coal fires, and to highlight them as a low-hanging fruit of immediate emissions reduction. This report summarizes CFG’s research for the WERC competition, for which this topic was chosen as an open task. Beyond raising awareness, CFG modeled, developed and built an experimentation apparatus meant to prove the validity of a relatively cheap extinguishing method which was also novel to the regions in which it could be employed. The apparatus, which simulated an underground coal fire, was used to test a sand …

Water System For Developing Countries / Disaster Relief Made With Local Materials, Dong Joon Lee

Chemical Engineering Undergraduate Honors Theses

As the equipment builder of the team, I was responsible for building the treadle pump, the sand filter tank, the hand pump, and generating the instructions for each equipment. Each team member was responsible for certain parts of the water purification system, but everyone worked cohesively on all parts of the design when assistance was necessary. The original design for the treadle pump was a two-man powered pump which discharged water at 15 gallons per minute. Since our system only required less than half of the flow rate, and required another person to operate the bicycle, the pump was redesigned …

Coal Fires: An Environmental Disaster, Turner Tomlinson

Chemical Engineering Undergraduate Honors Theses

The mission of the Coal Fire Gang (CFG) is to spread awareness about the global issue of uncontrolled coal fires, and to highlight them as a low-hanging fruit of immediate emissions reduction. This report summarizes CFG’s research for the WERC competition, for which this topic was chosen as an open task. Beyond raising awareness, CFG modeled, developed and built an experimentation apparatus meant to prove the validity of a relatively cheap extinguishing method which was also novel to the regions in which it could be employed. The apparatus, which simulated an underground coal fire, was used to test a sand …

Water System For Developing Countries / Disaster Relief Made With Local Materials, Lauren E. Cole

Chemical Engineering Undergraduate Honors Theses

At the beginning of this project, I elected to focus mainly on the electrolysis portion. I completed a lot of research on electrolysis in general, and then specifically on brine electrolysis, which is transforming a salt water solution into a sodium hypochlorite solution, or bleach. I researched all of the different types of electrode materials and purchased several electrodes in order to perform experiments. I researched several methods of electrolysis in use today. I performed several calculations about the electrolysis reaction, including the electric potential required to drive the reaction (approximately 1.0 volt), as well as what concentration of salt …

Homochiral Metal-Organic Materials: Design, Synthetic And Enantioseletive Separation, Shi-Yuan Zhang

USF Tampa Graduate Theses and Dissertations

Owing to the growing demand for enantiopurity in biological and chemical processes, tremendous efforts have been devoted to the synthesis of homochiral metal-organic materials (MOMs) because of their potential applications in chiral separation and asymmetric catalysis. In this dissertation, the synthetic strategies for homochiral MOMs are discussed keeping the focus on their applications. Two distinct approaches have been taken to synthesize chiral structures with different topologies and accessible cavities. The chiral MOMs have been utilized in enantioselective separation of racemates.

Chiral variants of the prototypal metal-organic framework MOF-5, δ-CMOF-5 and [lambda]-CMOF-5, have been synthesized by preparing MOF-5 in the presence …

Study Of Water Transport Phenomena On Cathode Of Pemfcs Using Monte Carlo Simulation, Karn Soontrapa

UNLV Theses, Dissertations, Professional Papers, and Capstones

This dissertation deals with the development of a three-dimensional computational model of water transport phenomena in the cathode catalyst layer (CCL) of PEMFCs. The catalyst layer in the numerical simulation was developed using the optimized sphere packing algorithm. The optimization technique named the adaptive random search technique (ARSET) was employed in this packing algorithm. The ARSET algorithm will generate the initial location of spheres and allow them to move in the random direction with the variable moving distance, randomly selected from the sampling range, based on the Lennard-jones potential of the current and new configuration. The solid fraction values obtained …

Simulations Of Interfacial Electrokinetics With Applications To Microfluidic Systems, Sebastian Uppapalli

UNLV Theses, Dissertations, Professional Papers, and Capstones

Electrokinetics plays an important role in facilitating fluid transport and particle manipulation in microfluidic systems. This dissertation studies the mechanics of electrokinetic phenomena for microscale particles and drops. The work aims to increase the understanding of complex electrokinetic phenomena for applications in Lab-on-Chip technology, assembly of colloidal particles and two-phase flow sensing. The standard model consisting of the Poisson-Nernst-Planck equations is used to study the electric double layer polarization of charged dielectric particles and channel wall which plays a major role in control and manipulation of colloidal particles and understanding of electrohydrodynamic flow field.

The cases of polarization of "soft" …

Design Of A Light-Weight Low-Volume High Oxygen Storage Density Material, Nicholas Robert Schwartz

Theses and Dissertations

A compact, lightweight, dense and safe method for storing and supplying oxygen remains a large hurdle for closed-circuit self-contained breathing apparatus (SCBA) and respiratory protective equipment. No filter that can protect against airborne chemical, biological, radiological, and nuclear (CBRN) contaminants exists, which presents the need for an isolated oxygen source. Heavy and high maintenance oxygen cylinders are typically used. The most important criteria for a smart and effective CBRN protection device are safety, weight, size, and cost, level of maintenance, ease-of-use and reliability. This study focused on nanomaterials for high capacity gas storage. Nanocapillary arrays composed of anodic aluminum oxide …

Comparing Virus Ultrafiltration Of Bacteriophages With Filtration Of Minute Virus Of Mice, Kent Smith

Graduate Theses and Dissertations

Industrial production of protein therapeutics demand rigorous testing and clearance of viruses. The U.S. Food and Drug Administration dictate the purity of pharmaceuticals with regards to viral contamination. As this testing is time consuming and expensive using mammalian cells and viruses, bacteriophages may provide a faster and cheaper alternative for membrane filtration processes. We used ultrafiltration membranes to filter protein solutions with viruses. Two bacteriophages were tested against membranes with two different pore sizes. These membranes were then tested by inverting the membrane's orientation. Flux measurements and log virus removal data were taken. Flux and log virus removal were seen …

Density Functional Theory Study Of The Thermodynamics Of Catalytic Remediation Of Nitrate In Water, Lizzie Bollmann

All Theses

Over 1 billion people worldwide lack access to safe drinking water and 5,000 people die each day due to drinking contaminated water. With the development of new industries, new substances and chemicals are entering the waters every day, and the current water treatment processes are unable to remove them entirely. For example, agriculture is the world's heaviest consumer of water, and nitrates and nitrites from fertilizers are washed away with the water to rivers and streams. These chemicals can cause problems to humans and to the environment. To humans, they can cause methemoglobinemia, also known as 'blue baby syndrome'. To …

Study Of The Structure-Property Relationships That Determine The Effects Of Latexes And Starch Containing Latex Emulsions On The Performance Of The Barrier Coatings (Sub-Coat) For Paper, Joanna Marie Monfils

Master's Theses

The history of carbonless paper dates back to the 1940s. Before this, a carbon copy sheet was needed between sheets of paper to be able to produce one or more copies simultaneously during writing. The pressure from a pen or typewriter would help deposit the ink of the carbon paper onto the blank sheet of paper under the original written sheet to create a “carbon copy.” This method did however, have its disadvantages. Not only did it produce a limited number of copies, but it was also a messy process. So came the creative process of using microencapsulated dyes to …