High-Density Non-Fouling Bioactive Coatings: Development And Characterization,
2017
Oregon State University
High-Density Non-Fouling Bioactive Coatings: Development And Characterization, Bonan Yu, Ramya Raman, Karl Schlike
Biomedical Engineering Western Regional Conference
No abstract provided.
Molecular Modeling Of Antibody-Antigen Binding Near Solid Surfaces,
2017
Brigham Young University
Molecular Modeling Of Antibody-Antigen Binding Near Solid Surfaces, Derek Bush, Thomas Knotts
Biomedical Engineering Western Regional Conference
Antibody microarrays are biosensors that have the potential to revolutionize molecular detection in medicine, scientific research, and national defense. However, current microarrays are not widely used due to problems including poor reproducibility and signal quality, unbalanced antibody performance, and cross-reactivity. Prior work in the area focused mainly on the stability of the antibody alone and not its affinity for its antigen. This presentation shows results of using molecular simulation to determine how different types of surfaces affect antigen binding to surface-tethered antibodies. The results offer an unprecedented, molecular-level view into these protein-protein-surface interactions and how to drive binding to occur.
A Novel Tantalum-Containing Bioglass. Part Ii. Development Of A Bioadhesive For Sternal Fixation And Repair,
2017
Missouri University of Science and Technology
A Novel Tantalum-Containing Bioglass. Part Ii. Development Of A Bioadhesive For Sternal Fixation And Repair, Adel Mf Alhalawani, Cina Mehrvar, Wendy Stone, Stephen D. Waldman, Mark R. Towler
Chemical and Biochemical Engineering Faculty Research & Creative Works
With over a million median sternotomy surgeries performed worldwide every year, sternal wound complications have posed a serious risk to the affected patients. A rigid therapeutic sternal fixation device has therefore become a necessity. In this work, the incorporation of up to 0.5 mol% of tantalum pentoxide (Ta2O5), in exchange for zinc oxide (ZnO), into the SiO2-ZnO-CaO-SrO-P2O5 glass system is presented. The effect of Ta incorporation on the physical, chemical and biological properties of the glass polyalkenoate cements (GPCs) prepared from them have been presented in this manuscript. The data obtained …
Electroanalytical Measurements Of Binary-Analyte Mixtures In Molten Licl-Kcl Eutectic: Uranium(Iii)- And Magnesium(Ii)-Chloride,
2017
Brigham Young University - Provo
Electroanalytical Measurements Of Binary-Analyte Mixtures In Molten Licl-Kcl Eutectic: Uranium(Iii)- And Magnesium(Ii)-Chloride, Devin Rappleye, Matthew L. Newton, Chao Zhang, Michael F. Simpson
Faculty Publications
The electrochemical behavior of MgCl2 in molten LiCl-KCl eutectic was investigated to evaluate its suitability as a surrogate for PuCl3 in studies related to the eletrorefining of used nuclear fuel. The reduction of Mg2+ was found to be electrochemically reversible up to 300 mV s−1 at 773 K. The diffusion coefficient for Mg2+ was calculated to be 1.74 and 2.17 × 10−5 cm2 s−1 with and without U3+ present, respectively, at 773 K using cyclic voltammetry (CV). Upon comparison to literature data, the diffusion coefficient of Mg2+ differs by only 8.8% (with U …
Eis Analysis Of Shear Enhanced Microfluidic Lab-On-A-Chip Device,
2017
New Jersey Institute of Technology
Eis Analysis Of Shear Enhanced Microfluidic Lab-On-A-Chip Device, Mehnaz Mursalat
Theses
Electrochemical sensors and biosensors have received much attention owing to the feasibility demonstrated regarding instrumental simplicity, decent cost, and portability during the detection of a wide range of biological and pharmaceutical macromolecules. Carbon-based nanomaterials, including carbon nanotubes, have garnered tremendous interest for their unique thermal, mechanical, electronic and catalytic properties while designing these sensors. Whenever the macromolecules interact with a bio-recognition element on the electrode transducer surface, a measurable change in the electrical current or potential takes place. To achieve lower limits of detection, the use of sensor surfaces modified with nanostructured materials such as nanotubes, or nanoparticles is becoming …
Real Time, Integrated, Paper Based Temperature Sensor For Lab On A Chip Device,
2017
New Jersey Institute of Technology
Real Time, Integrated, Paper Based Temperature Sensor For Lab On A Chip Device, Vignesh Shekhar
Theses
Temperature measurement and manipulation is a critical factor in a wide range of applications like Point Of Care Diagnostics (POC's), Polymerase Chain Reaction (PCR), Temperature Gradient Focusing (TGF) to cite few prominent examples. In the past decade, researchers have used various techniques to sense and control the temperature in microfluidic systems. The primary challenge has been the twin problem of integration and accuracy using minimal equipment while keeping it simple. In this study, an equipment free fabrication of the temperature sensor using filter paper impregnated with p-type colloidal PbS quantum dots is demonstrated. This sensor is later integrated into line …
Novel Experimental Method For The Determination Of The Minimum Agitation Speed For Solids Suspension In Flat-Bottomed Stirred Tank Reactors,
2017
New Jersey Institute of Technology
Novel Experimental Method For The Determination Of The Minimum Agitation Speed For Solids Suspension In Flat-Bottomed Stirred Tank Reactors, Shriarjun Shastry
Theses
Knowledge of the minimum agitation speed, Njs, required to suspend finely divided solids in vessels stirred by an impeller is a critical parameter to properly operate industrial tanks in a large number of industrial operations. The most common experimental approach to measure Njs is that of Zwietering’s (Chem. Eng. Sci., 1958, 8, 244-253), consisting of visually inspecting the tank bottom and visually determining the impeller agitation speed at which the solids are observed to rest on the tank bottom for no more than 1-2 seconds before being swept away. This method is quite reliable, but a method …
Field-Induced Formation And Growth Of Pillars On Films Of Bisphenol-A-Polycarbonate,
2017
National Tsing Hua University, Taiwan
Field-Induced Formation And Growth Of Pillars On Films Of Bisphenol-A-Polycarbonate, Yu-Fan Chuang, Jyun-Siang Peng, Fuqian Yang, Donyau Chiang, Sanboh Lee
Chemical and Materials Engineering Faculty Publications
An electric field is used to construct pillars on films of bisphenol-A-polycarbonate (BPAPC) between two parallel electrodes. Both the size and density of the pillars are dependent on the film thickness. For the same experimental conditions, thicker films will lead to the formation of pillars of larger sizes and smaller densities. The time dependence of the average diameter of the pillars is found to be a linear function of the square root of the difference between the annealing time and incubation time. The temperature dependence of the temporal evolution of the pillars follows the Arrhenius relation with an activation enthalpy …
The Potential Of Elephant Grass (Pennisetum Purpureum Schum), An African Indigenous Grass, In Bioethanol Production: A Decarbonization Alternative For The Shipping Industry,
2017
World Maritime University
The Potential Of Elephant Grass (Pennisetum Purpureum Schum), An African Indigenous Grass, In Bioethanol Production: A Decarbonization Alternative For The Shipping Industry, Lawrence Kuroshi Phd
MARENER 2017
While it is true that fossil fuel based energy which is non-renewable has contributed immensely to global economic growth, it has brought with its usage the emission of carbon dioxide (CO2), a principal greenhouse gas. Studies using business as usual (BAU) model has predicted that the emission of CO2 into the atmosphere will increase by 50 to 250% by the year 2050 with perhaps a commensurate increase in the global carbon footprint. The shipping industry has remained a major contributor to this global carbonization. Concern over this increasing concentration of carbon dioxide in the atmosphere, has intensified interests in developing …
Catalytic Upgrading Of Biogas To Fuels: Role Of Reforming Temperature, Oxidation Feeds, And Contaminants,
2017
University of South Florida
Catalytic Upgrading Of Biogas To Fuels: Role Of Reforming Temperature, Oxidation Feeds, And Contaminants, Nada Elsayed
USF Tampa Graduate Theses and Dissertations
Global energy demands are constantly increasing and fossil fuels are a finite resource. The shift towards alternative, more renewable and sustainable fuels is inevitable. Furthermore, the increased emissions of greenhouse gases have forced a pressing need to find cleaner, more environmentally friendly sources of fuel. Biomass energy is a promising alternative fuel because it offers several important advantages. It is a renewable energy form, it comes from many sources and produces biogas (CH4 and CO2). Furthermore, it can have a zero carbon footprint; this is due to the fact that the carbon produced is from the same …
Engineering A Fluorescent Protease Sensor For In Vivo Protein Detection,
2017
University of Connecticut
Engineering A Fluorescent Protease Sensor For In Vivo Protein Detection, Thomas C. Kinard
Honors Scholar Theses
This report details the results of an ongoing project to engineer a mutant form of Red Fluorescent Protein (RFP) variant mCherry that acts as a real-time in vivo protease sensor. The sought-after mutant only becomes fluorescent when exposed to Tobacco Etch Virus (TEV) Protease, this system’s model protease. This will be accomplished via the insertion of the TEV Protease Recognition Site (TEV-PRS) in such a position that, before cleavage, will prevent the protein from folding to fluorescent conformation, but upon cleavage, will allow for fluorescent conformation to occur. The cylindrical structure of the protein, composed of beta-pleated sheets, contains “loops” …
Fatigue Properties And Damage Mechanism Of A Cr-Mn Austenite Steel,
2017
Yanshan University, China
Fatigue Properties And Damage Mechanism Of A Cr-Mn Austenite Steel, Z. Q. Lv, Pei Cai, T. Yu, Yan Jin, H. F. Zhang, Tongguang Zhai, W. T. Fu
Chemical and Materials Engineering Faculty Publications
The fatigue properties and the damage mechanism of a Cr-Mn austenite steel were investigated using four-point bend fatigue testing. The stress-number of cycles to failure (S-N) curve of the Cr-Mn austenite steel was measured at room temperature, at the frequency of f=20 Hz and the stress ratio of R=0.1. The fatigue strength of this Cr-Mn austenite steel was measured to be 503 MPa in the maximum stress. Multiple cracks are initiated on the sample surface after fatigue failure tests, and usually only one or two of them can lead to the final failure of the samples. Most of the cracks …
Producing Food Packaging Printing Ink Via Green Emulsion Aggregation Method,
2017
Department of Printing Science and Technology, Institute for Color Science and Technology
Producing Food Packaging Printing Ink Via Green Emulsion Aggregation Method, Maryam Ataeefard, Shohre Rouhani
Journal of Applied Packaging Research
Digital printing will become more and more important in the packaging industry. Digital printing technology is growing because it allows the print suppliers to improve the level of service they offering to their customers, as well as, it opens new opportunities and helps them to make more money. Additives, dyestuffs, resin and other chemicals in packaging printing ink may influence safety of the food. Therefore, choosing suitable materials are very important in food packing ink. Over the last years, many printing ink manufacturers moved toward more sustainable inks. Drivers for this development, besides the resource scarcity and a higher legislative …
The Effect Of Graphene On Catalytic Performance Of Palladium Nanoparticles Decorated With Fe3o4, Co3o4, And Ni (Oh)2: Potential Efficient Catalysts Used For Suzuki Cross—Coupling,
2017
The British University in Egypt
The Effect Of Graphene On Catalytic Performance Of Palladium Nanoparticles Decorated With Fe3o4, Co3o4, And Ni (Oh)2: Potential Efficient Catalysts Used For Suzuki Cross—Coupling, Hany A. Elazab Dr
Chemical Engineering
In this research, we report a scientific investigation of an efficient method used for the synthesis of highly active Palladium Nanoparticles decorated with Fe3O4, Co3O4, and Ni (OH)2 Supported on Graphene as Potential Efficient Catalysts for Suzuki Cross—Coupling. Pd/Fe3O4 nanoparticles supported on graphene nanosheets (Pd/ Fe3O4/G) showed an excellent catalytic activity for Suzuki coupling reactions and recycled for up to four times without loss of catalytic activity. An efficient magnetic catalyst has been successfully synthesized using a simple, reproducible fast and reliable method using microwave irradiation conditions. The prepared catalysts are magnetic as in case of iron and cobalt oxides …
Interplay Of Composition, Structure, And Electron Density Of States In W-Os Cathode Materials And Relationship With Thermionic Emission,
2017
University of Kentucky
Interplay Of Composition, Structure, And Electron Density Of States In W-Os Cathode Materials And Relationship With Thermionic Emission, Qunfei Zhou, Thomas John Balk, Matthew J. Beck
Chemical and Materials Engineering Faculty Publications
The presence and composition of W-Os alloys have been found to significantly affect the thermionic emission properties of Os-coated tungsten dispenser cathodes. However, the comprehensive understanding of structure–property relationships needed to design improved tungsten cathodes with larger thermionic emission is still lacking. In this study, composition–structure–property relationships governing thermionic emission from W-Os alloys were investigated using quantum mechanical calculations. Low-energy W-Os atomic configurations at various compositions were determined from first-principles calculations based on density functional theory in combination with cluster expansion calculations. Electronic properties were investigated in terms of the electron density of states. The relative position of the Fermi …
Idiosyncratic Drug-Induced Liver Injury (Idili): Potential Mechanisms And Predictive Assays,
2017
Cleveland State University
Idiosyncratic Drug-Induced Liver Injury (Idili): Potential Mechanisms And Predictive Assays, Alexander D. Roth, Moo-Yeal Lee
Chemical & Biomedical Engineering Faculty Publications
Idiosyncratic drug-induced liver injury (IDILI) is a significant source of drug recall and acute liver failure (ALF) in the United States. While current drug development processes emphasize general toxicity and drug metabolizing enzyme- (DME-) mediated toxicity, it has been challenging to develop comprehensive models for assessing complete idiosyncratic potential. In this review, we describe the enzymes and proteins that contain polymorphisms believed to contribute to IDILI, including ones that affect phase I and phase II metabolism, antioxidant enzymes, drug transporters, inflammation, and human leukocyte antigen (HLA). We then describe the various assays that have been developed to detect individual reactions …
Inhibition Of Mammalian Glycoprotein Ykl-40 Identification Of The Physiological Ligand,
2017
University of Kentucky
Inhibition Of Mammalian Glycoprotein Ykl-40 Identification Of The Physiological Ligand, Abhishek A. Kognole, Christina M. Payne
Chemical and Materials Engineering Faculty Publications
YKL-40 is a mammalian glycoprotein associated with progression, severity, and prognosis of chronic inflammatory diseases and a multitude of cancers. Despite this well documented association, identification of the lectin′s physiological ligand and, accordingly, biological function has proven experimentally difficult. YKL-40 has been shown to bind chito-oligosaccharides; however, the production of chitin by the human body has not yet been documented. Possible alternative ligands include proteoglycans, polysaccharides, and fibers like collagen, all of which makeup the extracellular matrix. It is likely that YKL-40 is interacting with these alternative polysaccharides or proteins within the body, extending its function to cell biological roles …
Hybrid Concentrated Solar Thermal Power Systems: A Review,
2017
University of Utah
Hybrid Concentrated Solar Thermal Power Systems: A Review, Kody M. Powell, Khalid Rashid, Kevin Ellingwood, Jake Tuttle, Brian D. Iverson
Faculty Publications
Concentrated solar power (CSP), or solar thermal power, is an ideal technology to hybridize with other energy technologies for power generation. CSP shares technology with conventional power generation and can be readily integrated with other energy types into a synergistic system, which has many potential benefits including increased dispatchability and reliability, improved efficiency, reduced capital costs through equipment sharing, and the opportunity for flexible operation by alternating between energy sources. Another advantage of CSP technology is the ability to readily store via thermal energy storage (TES), making the intermittent solar resource dispatchable. A review of CSP hybridization strategies with coal, …
Geometry-Driven Folding Of A Floating Annular Sheet,
2017
Syracuse University
Geometry-Driven Folding Of A Floating Annular Sheet, Joseph Paulsen, Vincent Démery, K. Buğra Toga, Zhanlong Qiu, Thomas P. Russell, Benny Davidovitch, Narayanan Menon
Physics - All Scholarship
Predicting the large-amplitude deformations of thin elastic sheets is difficult due to the complications of self contact, geometric nonlinearities, and a multitude of low-lying energy states. We study a simple twodimensional setting where an annular polymer sheet floating on an air-water interface is subjected to different tensions on the inner and outer rims. The sheet folds and wrinkles into many distinct morphologies that break axisymmetry. These states can be understood within a recent geometric approach for determining the gross shape of extremely bendable yet inextensible sheets by extremizing an appropriate area functional. Our analysis explains the remarkable feature that the …
Lab-Scale Reproduction Of Siloxane Foam Synthesis,
2017
Virginia Commonwealth University
Lab-Scale Reproduction Of Siloxane Foam Synthesis, Albert Deangelis, Benjamin Ledoux, Conrad Roos
Capstone Design Expo Posters
Evonik has a synthesis reaction to create siloxane-based foam for sale that they run in their Hopewell plant. They would like to utilize a bench scale reactor system for experimentation on the process. The problem is that the foam created on the lab scale does not show the same properties as the foam created on the plant scale and to run experiments accurately they would have to use the plant reactor, wasting both reactor time and plant resources. Evonik wanted the Senior Design team to find a way of recreating the conditions of the plant reactor on the lab scale …
