Toxicity Evaluation Of Magnetic Hyperthermia Induced By Remote Actuation Of Magnetic Nanoparticles In 3d Micrometastasic Tumor Tissue Analogs For Triple Negative Breast Cancer,
2017
University of Kentucky
Toxicity Evaluation Of Magnetic Hyperthermia Induced By Remote Actuation Of Magnetic Nanoparticles In 3d Micrometastasic Tumor Tissue Analogs For Triple Negative Breast Cancer, Nathanael A. Stocke, Pallavi Sethi, Amar Jyoti, Ryan Chan, Susanne M. Arnold, J. Zach Hilt, Meenakshi Upreti
Chemical and Materials Engineering Faculty Publications
Magnetic hyperthermia as a treatment modality is acquiring increased recognition for loco-regional therapy of primary and metastatic lung malignancies by pulmonary delivery of magnetic nanoparticles (MNP). The unique characteristic of magnetic nanoparticles to induce localized hyperthermia in the presence of an alternating magnetic field (AMF) allows for preferential killing of cells at the tumor site. In this study we demonstrate the effect of hyperthermia induced by low and high dose of MNP under the influence of an AMF using 3D tumor tissue analogs (TTA) representing the micrometastatic, perfusion independent stage of triple negative breast cancer (TNBC) that infiltrates the lungs. …
Incorporating Poly(3-Hexyl Thiophene) Into Orthogonally Aligned Cylindrical Nanopores Of Titania For Optoelectronics,
2017
University of Kentucky
Incorporating Poly(3-Hexyl Thiophene) Into Orthogonally Aligned Cylindrical Nanopores Of Titania For Optoelectronics, Suraj R. Nagpure, James F. Browning, Stephen E. Rankin
Chemical and Materials Engineering Faculty Publications
The incorporation of hole conducting polymer poly(3-hexyl thiophene) (P3HT) into the 8-9 nm cylindrical nanopores of titania is investigated using films with a unique orthogonally oriented hexagonal close packed mesostructure. The films are synthesized using evaporation induced self-assembly (EISA) with Pluronic triblock copolymer F127 as the structure directing agent. The orthogonally oriented cylindrical nanopore structure was chosen over a cubic structure because confinement in uniform cylindrical channels is hypothesized to enhance hole conductivity of P3HT by inducing local polymer chain ordering. Orthogonal orientation of the cylindrical nanopores is achieved by modifying the substrate (FTO-coated glass slides) with crosslinked F127. After …
A Novel Tantalum-Containing Bioglass. Part I. Structure And Solubility,
2017
Missouri University of Science and Technology
A Novel Tantalum-Containing Bioglass. Part I. Structure And Solubility, Adel Mf Alhalawani, Mark R. Towler
Chemical and Biochemical Engineering Faculty Research & Creative Works
Bio glasses are employed for surgical augmentation in a range of hard tissue applications. Tantalum is a bioactive and biocompatible transition metal that has been used as an orthopedic medical device. It has a range of biological and physical properties that make its incorporation into ionic form into bioactive glass systems promising for various clinical applications. The work herein reports the characterization and properties of novel tantalum-containing glasses. A series of glasses based on the system 48SiO2-(36-X)ZnO-6CaO-8SrO-2P2O5-XTa2O5 with X varying from 0 mol% (TA0) to 0.5 mol% (TA2) were synthesized. The …
Evaluation Of Procedures To Quantify Solvent Retention In Electrospun Fibers And Facilitate Solvent Removal,
2017
Missouri University of Science and Technology
Evaluation Of Procedures To Quantify Solvent Retention In Electrospun Fibers And Facilitate Solvent Removal, Anthony R. D'Amato, Nicholas J. Schaub, Jesus M. Cardenas, Erich Franz, Deniz Rende, Alexis M. Ziemba, Ryan J. Gilbert
Chemical and Biochemical Engineering Faculty Research & Creative Works
Electro spun fiber scaffolds crafted from polyesters are studied extensively for potential tissue engineering applications. For translation of electro spun fibers into the clinic, the FDA requires analysis and quantification of any organic solvent that may be retained in the fibers since many organic solvents can negatively affect cells and tissues. If a significant amount of solvent is retained, then developing procedures for efficient solvent removal may enhance the clinical potential of these materials. In this study we use fourier transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA), and nuclear magnetic resonance spectroscopy (NMR) to analyze solvent retention. A correlative analysis …
Engineering Cell-Free Protein Synthesis Technology For Codon Reassignment, Biotherapeutics Production Using Just-Add-Water System, And Biosensing Endocrine Disrupting Compounds,
2017
Brigham Young University
Engineering Cell-Free Protein Synthesis Technology For Codon Reassignment, Biotherapeutics Production Using Just-Add-Water System, And Biosensing Endocrine Disrupting Compounds, Sayed Mohammad Salehi
Theses and Dissertations
Cell-free protein synthesis is an emerging technology that has many applications. The open nature of this system makes it a compelling technology that can be manipulated to answer many needs that are unavailable in other systems. This dissertation reports on engineering this technology for: 1) sense codon emancipation for incorporation of multiple unnatural amino acids; 2) expressing a hard-to-express anticancer biotherapeutic and introducing a just-add-water system; 3) a biosensing ligand that interacts with nuclear hormone receptors. Emancipating sense codons toward a minimized genetic code is of significant interest to science and engineering. A promising approach to sense codon emancipation is …
The Problem Of The Anode Electrolyte In H-Type Electrolytic Cell For Electrochemical Reduction Of Carbon Dioxide,
2017
School of Chemical Engineering and Technology, Harbin Institute of Technology, No.92 West-Da Zhi Street, Harbin, 150001 China;College of Material Science and Chemical Engineering, Harbin Engineering University, Harbin, 150001 China;Chaowei Power Co., LTD, Changxing, 313100 China;
The Problem Of The Anode Electrolyte In H-Type Electrolytic Cell For Electrochemical Reduction Of Carbon Dioxide, Rui Zhang, Wei-Xin Lv, Li-Xu Lei
Journal of Electrochemistry
Electrochemical reduction of carbon dioxide (CO2) was studied in the H-type electrolytic cell. It was found that the voltage between the cathode and the anode would increase during the long time electrolysis process, for this reason the electrolytic process would be unsustainable. After the experimental investigations carried out by constant potential electrolysis, constant current electrolysis, pH test and KHCO3 concentration analysis of anode electrolyte before and after the electrolysis, the increase in cell voltage might be caused by the following process: H+, that was generated from the anodic oxygen evolution reaction, reacted with HCO3 …
Application Of Composite Ionic Liquid In Electro-Oxidation Activation Of A C-H Bond,
2017
State Key Laboratory of Physical Chemistry of Solid Surfaces, Department of Chemistry,College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, Fujian, China;
Application Of Composite Ionic Liquid In Electro-Oxidation Activation Of A C-H Bond, Zi-Ying Chen, Qian-Qian Wu, Jian-Qing Zhang, Ying-Hong Zhu, Chun-An Ma
Journal of Electrochemistry
In this paper, the ionic liquid/carbon nanotube composite material was prepared through modifying the ionic liquid 1-ethyl-3-methylimidazolium acetate to multi-walled carbon nanotubes. The electro-oxidation properties of p-methoxy toluene (p-MT) were studied using the composite as an electrolyte. The effects of scanning speed, temperature and substrate concentration were studied by cyclic voltammetry and chronoamperometry. The electrochemical kinetics of p-MT in this system was also studied. The results showed that the electrochemical oxidation of p-MT in the composite electrolyte solution was irreversible. The process was mainly controlled by diffusion, and the diffusion coefficient (D) was 7.69×10-10 cm2·s-1. Increasing …
Electrochemical Synthesis Of Porous Polyaniline Electrodes Using Hkust-1 As A Template And Their Electrochemical Supercapacitor Property,
2017
State Key Laboratory of Chemical Engineering, East China University of Science and Technology, Shanghai 200237,;
Electrochemical Synthesis Of Porous Polyaniline Electrodes Using Hkust-1 As A Template And Their Electrochemical Supercapacitor Property, Qiong Luan, Chun-Feng Xue, Hong-Ye Zhu, Fu-Juan Yang, Xu-Li Ma, Xiao-Gang Hao
Journal of Electrochemistry
Excellent electrode plays vital important role in the performance of supercapacitors. Polyaniline (PANI) with good conductivity is often used to prepare electrode. However, its available surface is limited and results in a poor supercapacitance in many cases. It is desirable to fabricate an electrode containing electroactive PANI with high surface area deriving from its porous structure. Here, the metal-organic framework (MOF) material with high surface area was selected as a hard template for synthesizing porous PANI. Microporous PANI composite electrodes (Micro-PANI/CC) were fabricated by depositing aniline on to carbon cloth (CC) pre-coated with MOF material of HKUST-1 using a unipolar …
Sn-Doped Α-Fe2O3 Photocatalyst Containing Oxygen Vacancy For Water-Splitting,
2017
School of Chemical Engineering, Nanjing University of Science and Technology, Nanjing 210094, P.R.China;
Sn-Doped Α-Fe2O3 Photocatalyst Containing Oxygen Vacancy For Water-Splitting, Zu-Hua Wang, Dong-Fang Niu, Hui-Cheng Li, Rong-Bin Du, Heng Xu, Xin-Sheng Zhang
Journal of Electrochemistry
The α-Fe2O3 nanoparticles containing oxygen vacancies were synthesized in atmospheric N2 by dip-dropping method without a high vacuum employed before annealing. The influences of annealing atmosphere and Sn-doping on the photocatalytic performance of α-Fe2O3 nanoparticles were studied by annealing the photocatalyst in N2 or air and adding SnCl4 to the precursor directly. The results showed that the current density of Sn-doping α-Fe2O3 annealed in N2 at 550 °C and 1.23 V (vs. RHE) was 35 times greater than that of pristine α-Fe2O3 annealed in …
Direct Electrochemistry Of Glucose Oxidase Based On Ws2 Quantum Dots And Its Biosensing Application,
2017
School of Chemistry and Material Science, Key Lab for Functional Materials Chemistry of Guizhou Province, Guizhou Normal University, Guiyang 550001, China;
Direct Electrochemistry Of Glucose Oxidase Based On Ws2 Quantum Dots And Its Biosensing Application, Chen-Lu Li, Hua-Ping Peng, Zhong-Nan Huang, Yi-Lun Sheng, Pei-Wen Wu, Xin-Hua Lin
Journal of Electrochemistry
In this study, a novel electrochemical glucose biosensor has been developed by immobilizing glucose oxidase (GOx) on tungsten disulfide quantum dots (WS2 QDs) on the surface of glassy carbon electrode (GCE). Transmission electron microscopy, UV-vis spectroscopy and cyclic voltammetry were employed to characterize the morphology, structure, and electrochemical behaviors of the as-prepared WS2 QDs and the biofilm modified electrode. The results suggested that the WS2 QDs could accelerate the electron transfer between the electrode and the immobilized enzyme, which enabled the direct electrochemistry of GOx without any electron mediator. Besides, the immobilized GOx in WS2 QDsfilm …
Application Of Adamantane Schiff Base Nickel Complexes/Graphene Oxide/Glassy Carbon Modified Electrode In Detection Of Carmine,
2017
College of Chemistry and Molecular Sciences, Wuhan University;
Application Of Adamantane Schiff Base Nickel Complexes/Graphene Oxide/Glassy Carbon Modified Electrode In Detection Of Carmine, Peng Guo, Zheng Liu, Hai-Ying Li, Li-Ming Ma
Journal of Electrochemistry
The Schiff base nickel complexes/graphene oxide/glassy carbon electrodes were prepared by embedded method and electrodeposition on which were used to quantitatively detect the contents of carmine. Cyclic voltammetry, chronoamperometry, scanning electron microscopy (SEM) and other methods were employed to characterize properties and morphologies of the modified electrodes. The results show that the adamantane double Schiff base nickel complexes/graphene oxide/glassy carbon electrode had high electric catalytic activity toward carmine oxidation reaction, and might provide an easy and quick way to detect carmine content with good reproducibility.
Application Of The Rotating Cylinder Electrode In Molten Licl-Kcl Eutectic Containing Uranium(Iii)- And Magnesium(Ii)-Chloride,
2017
Brigham Young University - Provo
Application Of The Rotating Cylinder Electrode In Molten Licl-Kcl Eutectic Containing Uranium(Iii)- And Magnesium(Ii)-Chloride, Devin Rappleye, Michael F. Simpson
Faculty Publications
The application of the rotating cylinder electrode (RCE) to molten LiCl-KCl eutectic mixtures for electroanalytical measurements is presented. This enabled the measurement of the limiting current which was observed to follow a linear trend with the rotational rate raised to 0.64–0.65 power on average, which closely agrees with existing RCE mass-transfer correlations. This is the first publication of electroanalytical RCE measurements in LiCl-KCl eutectic based molten salt mixtures, to our knowledge. These measurements were made in mixtures of molten LiCl-KCl eutectic containing UCl3 and MgCl2. Kinetic parameters were calculated for Mg2+ in LiCl-KCl eutectic. The exchange …
In-House Fabrication Of Temperature Sensitive Paint For Turbine Cooling Research,
2017
Embry-Riddle Aeronautical University
In-House Fabrication Of Temperature Sensitive Paint For Turbine Cooling Research, Mayur D. Patel, Mark A. Ricklick
Beyond: Undergraduate Research Journal
The Temperature Sensitive Paint (TSP) is a widely used method in measuring and visualizing flow separation and heat transfer. Compared to the cost and time consumption needed for methods such as pitot tubes, temperature sensitive paint is a cheaper alternative. Due to high usage in College of Engineering research projects, it was determined that in house fabrication of temperature sensitive paint would reduce time and cost limitations. For initial stages, literature research was performed to determine the recipe of intensity based TSP with luminophore and polymer binder that operated optimum at temperatures from 0-100°C. Europium III thenoyltrifluoroacetonate was determined to …
Synthesis Of Novel, Highly Bio-Based Monomeric Materials Derived From Lignocellulosic Biomass And Their Respective Epoxy Resins, Polycarbonates, And Polyesters,
2017
Rowan University
Synthesis Of Novel, Highly Bio-Based Monomeric Materials Derived From Lignocellulosic Biomass And Their Respective Epoxy Resins, Polycarbonates, And Polyesters, Joseph Randall Mauck
Theses and Dissertations
The development of high performance polymers from renewable feedstocks is a crucial step toward a global economy that is less dependent on fossil resources and has been a field of increasing study. The development of novel and interesting bio-based monomers, resins, and functional building blocks is critical to the improvement of polymers produced across the field, as well as to increasing the resource base from which chemical and materials engineers can draw to meet specific polymer property requirements. To this end, interesting tri-functional (trisguaiacol) and 4-vinyl guaiacol based hetero-difunctional monomers were developed and screened for preliminary polymer properties. The applications …
Characterization And Fracture Property Of Different Strontium-Containing Borate-Based Glass Coatings For Ti6al4v Substrates,
2017
Missouri University of Science and Technology
Characterization And Fracture Property Of Different Strontium-Containing Borate-Based Glass Coatings For Ti6al4v Substrates, Yiming Li, Ali Matinmanesh, Declan J. Curran, Emil H. Schemitsch, Paul Zalzal, Marcello Papini, Anthony W. Wren, Mark R. Towler
Chemical and Biochemical Engineering Faculty Research & Creative Works
This work considered the effect of increasing Strontium ion (Sr2+) content on the structure of a series of glasses based on the B2O3-P2O5-CaCO3-Na2CO3-TiO2-SrCO3 series and their resultant fracture toughness when coated onto a surgical metal substrate. Six glasses with increasing Sr2+ content (0 to 25 mol%) were synthesized and subsequently characterized by X-ray Diffraction (XRD), Differential Thermal Analysis (DTA) and both Magic Angle Spinning Nuclear Magnetic Resonance (MAS-NMR) and Raman Spectroscopy. These techniques confirmed that increased Sr2+ content induced …
Preparation Of Hydrogel Based On Acryl Amide And Investigation Of Different Factors Affecting Rate And Amount Of Absorbed Water,
2017
The British University in Egypt
Preparation Of Hydrogel Based On Acryl Amide And Investigation Of Different Factors Affecting Rate And Amount Of Absorbed Water, Hany A. Elazab Dr
Chemical Engineering
Hydrogel is considered as an important material in our world nowadays as it is used in many important and significant applications such as in tissue engineering and agriculture. There are hundreds of types of such materials, where most of them can be easily prepared. The main objective of this work is to prepare one of the hydrogel types which could be very useful in the agriculture of deserts where plants in dry places require water in order to grow up. There are many places around the world where raining occurs only once or twice a year. There are also places …
Examination Of The Effect Of Differential Molecular Diffusion In Dns Of Turbulent Non-Premixed Flames,
2017
Purdue University
Examination Of The Effect Of Differential Molecular Diffusion In Dns Of Turbulent Non-Premixed Flames, Chao Han, David O. Lignell, Evatt R. Hawkes, Jacqueline H. Chen, Haifeng Wang
Faculty Publications
The effect of differential molecular diffusion (DMD) in turbulent non-premixed flames is studied by examining two previously reported DNS of temporally evolving planar jet flames, one with CO/H2 as the fuel and the other with C2H4 as the fuel. The effect of DMD in the CO/H2 DNS flames in which H2 is part of fuel is found to behave similar to laminar flamelet, while in the C2H4 DNS flames in which H2 is not present in the fuel it is similar to laminar flamelet in early stages but becomes different from laminar flamelet later. The scaling of the effect …
Remediating 1,4-Dioxane-Contaminated Water With Slow-Release Persulfate And Zerovalent Iron,
2017
University of Nebraska-Lincoln
Remediating 1,4-Dioxane-Contaminated Water With Slow-Release Persulfate And Zerovalent Iron, Ann Kambhu, Megan Gren, Wei Tang, Steve D. Comfort, Clifford Harris
Nebraska Water Center: Faculty Publications
1,4-dioxane is an emerging contaminant that was used as a corrosion inhibitor with chlorinated solvents. Metal-activated persulfate can degrade dioxane but reaction kinetics have typically been characterized by a rapid decrease during the first 30 min followed by either a slower decrease or no further change (i.e., plateau). Our objective was to identify the factors responsible for this plateau and then determine if slow-release formulations of sodium persulfate and Fe0 could provide a more sustainable degradation treatment. We accomplished this by conducting batch experiments where Fe0-activated persulfate was used to treat dioxane. Treatment variables included the timing …
Beating Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes On Porcine Extracellular Matrix,
2017
Brigham Young University - Provo
Beating Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes On Porcine Extracellular Matrix, Kaitlyn J. Mcentire, Alonzo Cook, Toph Knutson, Gevan Eldredge, Hunter Behrmann, Clayton Holding, Matthew Hodgson, Dillon Despain, Jacob Preslar, Joseph Rich, Matthew Stephens, Matthew Trone, Michael Neff, Sam Worrall, Joshua Mcclellan, Abbie Kondel, Donnie Pfeifer
Biomedical Engineering Western Regional Conference
Despite modern technology and developments in heart disease treatment and prevention, heart disease remains the number one cause of death in America. With an inability to meet an ever-increasing demand for heart transplants and the dangers of immunosuppressant drugs, any potential alternative to cardiac transplantation must be pursued. The end goal of this research is to engineer biocompatible tissues that are fully functional to repair or replace damaged portions of the heart following the loss of cardiac function. This research investigates the effect of porcine extracellular matrix as the scaffold for beating IPS-differentiated cardiomyocytes.
Design And Evaluation Of 3d Printed Features To Improve Stability Of Plasma-Cell Pack Interface In Bacteria Separating Hollow Spinning Disk,
2017
Brigham Young University - Provo
Design And Evaluation Of 3d Printed Features To Improve Stability Of Plasma-Cell Pack Interface In Bacteria Separating Hollow Spinning Disk, Colin G. Bledsoe, Ryan L. Wood, Daneil S. Mcclellan, Dr. William G. Pitt
Biomedical Engineering Western Regional Conference
PDF submission of abstract.
