A Simple Quantitative Method Using Tlc-Image Analysis To Determine Fructooligosaccharides (Fos) In Food Samples,
2022
TÜBİTAK
A Simple Quantitative Method Using Tlc-Image Analysis To Determine Fructooligosaccharides (Fos) In Food Samples, Diana Beatriz Muñiz Márquez, Marco Antonio Mártinez Cervantes, Alain Martinez, Cristobal Aguilar, Pedro Agui̇lar Zarate, Jorge Enrique Wong Paz
Turkish Journal of Chemistry
The thin-layer chromatography technique (TLC) is a simple and inexpensive analysis commonly used to identify qualitatively the presence of carbohydrates in food samples such as mono- di and oligosaccharides particularly. TLC assay could be improved using image processing software for the semiquantitative determination of this type of compound. In the present work, TLC-image analysis with Silica Gel 60 TLC plates was used for the semiquantitative determination of 6 standards of carbohydrates (glucose, fructose, sucrose, 1-kestose, nystose, and fructofuranosylnystose). Subsequently, the areas of the spots of each compound were determined by digitizing in a conventional office scanner. Then, the segmentation of …
Development Of Software For The Calculation Of Kinetic Parameters From Solid Phase Reaction Data, Application To Synthesized N'-(4-Chlorobenzoyl)-N,N-Di-N-Butylthiourea Ligand And Its Nickel (Ii) Complex, Esra Kalem, Nevzat Külcü
Turkish Journal of Chemistry
In gas and liquid phase reactions, the conversion of starting materials to products is directly controlled by the rate of the reaction, whereas in solid state reactions, it is determined by the rate of diffusion. When working with thermal analysis methods, tens of thousands of data to be obtained from measured differential thermal analysis (DTA), thermal gravimetry (TG), and differential thermal gravimetry (DTG) curves must first be digitized, and then these digitized data must be converted to concentrations and thermal values using appropriate software programs. Companies that produce devices using thermal analysis techniques generally adapt the encrypted software programs they …
Impacts Of Some Metal Ions On Glutathione S-Transferase In The Liver Of Chalcalburnus Tarichi: An Endemic Species Of Lake Van,
2022
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Impacts Of Some Metal Ions On Glutathione S-Transferase In The Liver Of Chalcalburnus Tarichi: An Endemic Species Of Lake Van, Muhammet Serhat Özaslan, Mehmet Çi̇ftci̇
Turkish Journal of Chemistry
Glutathione-S-transferase (GSTs) is a multifunctional enzyme that provides homeostasis by catalyzing the first step of the formation of mercapturic acid, the end product in detoxification metabolism. They can prevent reactive electrophilic compounds from harming the body by covalently binding the same type of compounds to each other. In this study, we determined the in vitro inhibitory effects of metal ions such as Cu2+, Cd2+, Ag+, and Co2+ on GST enzyme activity. For this aim, GST was purified from C. tarichi Pallas liver with 37.36% yield and 29.304 EU/mg specific activity using the chromatographic method. The Vmax values of liver GST …
Determination Of Triacylglycerol And Fatty Acid Compositions Of Impatiens Seed Oils Using Reverse Phase High Performance Liquid Chromatography, Anh Van Nguyen, Anh Thi Ngoc Vu, Victor Ivanovic Deineka, Huy-Trung-Kien Nguyen
Turkish Journal of Chemistry
In the present work, triacylglycerol and fatty acid compositions of Impatiens balsamina L. and Impatiens walleriana Hook.f. seed oils were determined using reverse phase high performance liquid chromatography with both refractive index and spectrophotometric detections. The presence of conjugated octadecatetraenoic moieties was confirmed by UV and IR spectroscopy. Triacylglycerol (TAG) compositions were performed using an incremental approach and confirmed by the results of MS and electronic spectra. The quantitative analysis of TAG was achieved by careful calibration, introducing correction factors for the sensitivity of each compound. The results showed that both Impatiens seed oils contain the same 23 TAGs. The …
Synthesis Of Titanium Dioxide Nanoparticles With Renewable Resources And Their Applications: Review,
2022
TÜBİTAK
Synthesis Of Titanium Dioxide Nanoparticles With Renewable Resources And Their Applications: Review, Umut Şafak Öztürk, Ali̇me Çitak
Turkish Journal of Chemistry
Metal-oxide nanoparticles have reached a wide range of applications in the last ten years. Titanium dioxide nanoparticles stand out with their unique crystal structure and near-perfect physical and chemical properties at nanoscales (crystal size between 10-100 nm). It has created many applications with its white pigment, semiconductor state, and effective photocatalytic properties, but the synthesis of these nanoparticles is very damaging to nature. Titanium dioxide nanoparticles, which can be synthesized with toxic solvents or high-energy machines, have started to be synthesized by the green synthesis method, which has been a cheap and easy method in recent years. The application areas …
Photocatalytic Degradation Of Aquatic Organic Pollutants With Zn- And Zr-Based Metalorganic Frameworks: Zif-8 And Uio-66,
2022
TÜBİTAK
Photocatalytic Degradation Of Aquatic Organic Pollutants With Zn- And Zr-Based Metalorganic Frameworks: Zif-8 And Uio-66, Fatma Defne Çalik, Bi̇lgesu Erdoğan, Esra Yilmaz, Gi̇zem Saygi, Seher Fehi̇me Çakicioğlu Özkan
Turkish Journal of Chemistry
Water treatment has been an essential issue with the increasing population over 40 years. Researchers center on the major organic pollutants, such as dyes, pesticides, and pharmaceutical products. Photocatalytic degradation is one of the promising methods for aquatic organic pollutant treatment. Over the years, scientists have been working on developments for photocatalysts to enhance their pollutant degradation performances. From the reviewed studies, it is seen that properties like surface area, chemical, mechanical, and thermal stability, and uniform distribution of active sites are crucial, and an increase in these properties provides better degradation efficiency. In this sense, metal-organic frameworks as photocatalysts …
A Review On The Achievement Of Enzymatic Glycerol Carbonate Production,
2022
TÜBİTAK
A Review On The Achievement Of Enzymatic Glycerol Carbonate Production, Selda Aydoğdu, Nurcan Kapucu
Turkish Journal of Chemistry
High energy demand driven by decreasing fossil fuels, and global warming because of the burning of fossil fuels necessitates the utilization of renewable and clean energy. One of these renewable energy sources is biodiesel. The increasing trend of biodiesel over the last 20 years tends to result in increasing glycerol (Gly), which is produced during the biodiesel production in 10% ratio (w/w) as a by-product. Using Gly as raw material is an alternative way to produce bio-based new products such as glycerol carbonate (GlyC). GlyC is a value-added product of Gly/vegetable oil and this product can be used as a …
The Study On Biological Activities Of Silver Nanoparticles Produced Via Green Synthesis Method Using Salvia Officinalis And Thymus Vulgaris, Ömer Ödemi̇ş, Sadi̇n Özdemi̇r, Serpi̇l Gonca, Ali̇ Arslantaş, Mehmet Sali̇h Ağirtaş
Turkish Journal of Chemistry
In the present study, Ag nanoparticles (AgNPs) were synthesized from Salvia officinalis and Thymus vulgaris, known as phytotherapy plants. The obtained silver nanoparticles were characterized using SEM, XRD, FTIR, and UV/Vis spectra. The antioxidant capacities of Salvia officinalis-mediated AgNP (SO-AgNP) and Thymus vulgaris-mediated AgNP (TV-AgNP) were analyzed in vitro using 1,1-diphenyl-2-picrylhydrazyl and iron chelating activity assays. DPPH activities were 83.74% and 57.17% for SO-AgNP and TV-AgNP at concentration 200 mg/L, respectively. Both green synthesized AgNPs exhibited good iron chelating activity. In addition, the DNA cleavage activities of SO-AgNPs and TV-AgNP were investigated with agarose gel electrophoresis technique. …
Synthesis And Antioxidant Activities Of Benzylic Bromophenols Inclusive Of Natural Products,
2022
TÜBİTAK
Synthesis And Antioxidant Activities Of Benzylic Bromophenols Inclusive Of Natural Products, Çeti̇n Bayrak, Eda Mehtap Üç, Mohsen Rezaei, İlhami̇ Gülçi̇n, Abdullah Menzek
Turkish Journal of Chemistry
The synthesis of natural products 2-(2,3-dibromo-4,5-dihydroxyphenyl)acetic acid (1) and 2-(2,6-dibromo-3,5-dihydroxyphenyl)acetic acid (2) and as well as their derivatives 25 and 26 were carried out by substitution, hydrolysis and demethylation reactions of the corresponding four benzyl bromides. The antioxidant potentials of benzylic acid-derived bromophenols were, for the first time, appraised by several outstanding bioanalytical methods. Besides these, we estimated the antioxidant effects which were studied using the methods of DPPH·, ABTS·+ scavenging activities, ferric (Fe3+) and cupric (Cu2+) ions and Fe3+-TPTZ reducing capacities. Benzylic acid-derived bromophenols were found as effective DPPH·, and …
Preparation Of Moo3/Mos2-E Composite For Enhanced Photoelectrocatalytic Removal Of Antimony From Petrochemical Wastewaters,
2022
TÜBİTAK
Preparation Of Moo3/Mos2-E Composite For Enhanced Photoelectrocatalytic Removal Of Antimony From Petrochemical Wastewaters, Sevi̇l Akçağlar
Turkish Journal of Chemistry
By doping of MoO3 to MoS2-E, MoO3/MoS2-E composite was produced to treat the antimony (Sb+5) from raw petrochemical industry wastewater. The effects of increasing MoO3/MoS2-E composite concentrations (0.01, 0.06, 0.50, 1.20, and 6 mg/L), times (5 min, 10 min, 20 min, 60 min, 80 min), and simulated sun light powers (2, 15, and 26 mW/m2) on the removal of Sb+5 was researched. According to X-ray diffraction (XRD), MoS2-E exhibited a pure hexagonal structure with peaks at 2θ data of 15.56, 33.78, 40.59, and 61.43 cm …
The 4-(Dimethylaminoalkyl)Piperazine Inhibitors Of Α-Glucosidase: Allosteric Enzyme Inhibition And Identification Of Interacting Chemical Groups, Usman Ghani, Sajda Ashraf, Zaheer Ul Haq, Zafer Asim Kaplancikli, Fati̇h Demi̇rci̇, Yusuf Özkay, Sibtain Afzal
Turkish Journal of Chemistry
In continuation of our interest in identifying new α-glucosidase inhibitors with potential to become antidiabetic drugs, this work focuses on the study of 4-(dimethylaminoalkyl)piperazine-1-carbodithioate derivatives as α-glucosidase inhibitors. The eight heterocyclic piperazine-dithiocarbamate complexes studied in this work contain a variety of substitutions on their benzene ring exhibiting potent, noncompetitive inhibition of α-glucosidase. Dithiocarbamate and piperazine moieties are important pharmacophores with promising therapeutic prospects featuring facilitated drug delivery due to their lipophilic nature in addition to their α-glucosidase inhibitory activity. Enzyme kinetics, molecular dynamics simulations, and docking studies revealed that the target compounds bind to a new allosteric site that is …
Ultrasound Phantom With Solids Mimicking Cancerous Tissue For Needle Breast Biopsy,
2022
TÜBİTAK
Ultrasound Phantom With Solids Mimicking Cancerous Tissue For Needle Breast Biopsy, Işik İpek Avci Yayla, Meli̇s Bi̇lal, Artür Salmaslioğlu, Erol Erçağ, Esma Sezer, Belkis Ustamehmetoglu
Turkish Journal of Chemistry
This study aimed at synthesizing hydrogels to simulate opaque breast tissue (BT) and coloured cancerous tissues (CT) at different densities of the designed phantom to improve the biopsy-related skills along with ultrasonography. Both tissues are tear-resistant and therefore, the phantom can be trained multiple times in order to lower the price and improve the eye-hand coordination of users. For this purpose, self-healing (SH) polyacrylamide (PAAm) hydrogels (SH hydrogel) obtained by free-radical polymerization of AAm, in the presence of chemical cross-linker, BAAm, physical cross-linker stearyl methacrylate, C18, and ammonium persulfate APS as initiator were used in the design of phantoms. Psyllium …
Schiff Base Containing Pyridine Groups Functionalized Water-Soluble Phthalocyanine: Synthesis, Photo-Physicochemical Properties, And Bovine Serum Albumin Binding Behavior, Öznur Dülger, Ali̇ Erdoğmuş
Turkish Journal of Chemistry
The novel pyridine bearing schiff base substituted metal-free (9), zinc(II) phthalocyanine (10), and its quaternized derivative (11) were designed and synthesized. These phthalocyanines were fully characterized by spectroscopic methods (FT-IR, UV-Vis, MALDI-TOF, and 1H NMR). The photo-physicochemical properties of these phthalocyanines were investigated in both DMSO and DMF for 10 and in both DMSO and aqueous solution for 11. The addition of pyridine bearing Schiff base groups as peripheral ligands showed an improvement in the photophysical and photochemical properties. In addition, a spectroscopic investigation of the binding behavior of the water-soluble zinc (II) phthalocyanine …
A New Electrochromic Copolymer Composed Of 4,7-Di(Thiophen-2-Yl)Benzo[C] [1,2,5] Thiadiazole And 3,4-Ethylenedioxythiophene,
2022
TÜBİTAK
A New Electrochromic Copolymer Composed Of 4,7-Di(Thiophen-2-Yl)Benzo[C] [1,2,5] Thiadiazole And 3,4-Ethylenedioxythiophene, Kübra Çeli̇k, Ari̇f Kivrak, Buket Çarbaş
Turkish Journal of Chemistry
A new electrochromic copolymer based on 4,7-di(thiophen-2-yl)benzo[c] [1,2,5]thiadiazole and 3,4-ethylenedioxythiophene was successfully obtained via the electrochemical polymerization method in the medium of electrolyte solution, which consists of 0.1 M tetrabutylammonium hexafluorophosphate and dichloromethane. In order to compare the electrochemical and chemical properties of the copolymer, the benzothiodiazole derivative and 3,4-ethylenedioxythiophene (EDOT) monomers, which are parts of the copolymer, are electrochemically polymerized, separately in the same environment and concentration with the copolymer. Poly(4,7-di(thiophen- 2-yl)benzo[c][1,2,5]thiadiazole) (P(TBT)) and poly(3,4-ethylenedioxythiophene) (PEDOT) polymers were obtained. Before starting the electrochemical synthesis, the initial oxidation potentials of the monomers that form the copolymer were compared via the …
Comparison Of Denaturing Agent Effects In Enzymatic N-Glycan Release For Human Plasma N-Glycan Analysis,
2022
TÜBİTAK
Comparison Of Denaturing Agent Effects In Enzymatic N-Glycan Release For Human Plasma N-Glycan Analysis, Haci Mehmet Kayili, Rokia Sakhta, Beki̇r Sali̇h
Turkish Journal of Chemistry
Glycosylation is an essential posttranslational modification observed in the living proteome. Glycosylation profiles in glycoproteins can change in commonly observed diseases such as cancer. Identifying these changes is crucial in discovering new biomarkers for the early diagnosis of cancer. One of the main steps of N-glycan analysis is to release N-glycans from glycoproteins by specific enzymes. The study compares common denaturing agent combinations used in N-glycan release methods. In the study, human plasma was used to test the release methods of N-glycans containing different detergent combinations. The released N-glycans were labeled with the procainamide tag, …
Interaction Of The Nitrogen-Containing Carbon Backbone Polymers With Essential Α-Amino Acids,
2022
TÜBİTAK
Interaction Of The Nitrogen-Containing Carbon Backbone Polymers With Essential Α-Amino Acids, Andrey Sorokin, Maria Lavlinskaya
Turkish Journal of Chemistry
The aim of this work is to research the interactions of water-soluble nitrogen-containing copolymers with essential amino acids in aqueous media. For this, poly(N-vinylformamide-co-N-vinylimidazole) and poly(N-vinylcaprolactam-co-N-vinylimidazole) random copolymers were synthesized by free radical polymerization. The products obtained are characterized by GPC, DLS, and FTIR. The copolymers have a narrow molecular weight distribution and low dispersity. The interactions of the obtained copolymers with histidine, proline, arginine, leucine, phenylalanine, and methionine were researched by UV spectroscopy, FTIR, and TEM. It was found that conjugation of the copolymers with amino acids correlates with the copolymer …
New 2-D Silver(I) Coordination Network Constructed From Thiomethyl Group-Substituted P-Tert-Butylthiacalix[4]Arene,
2022
TÜBİTAK
New 2-D Silver(I) Coordination Network Constructed From Thiomethyl Group-Substituted P-Tert-Butylthiacalix[4]Arene, Huri̇ye Akdaş Kiliç, Ernest Graf, Mi̇r Wai̇s Hossei̇ni̇, Nathali̇e Kyri̇tsakas
Turkish Journal of Chemistry
New ligand based on p-tertbutyltetrathiacalix[4]arene blocked in 1,3-alternate conformation, was achieved via a multistep synthesis with the introduction of thiomethylpropoxy groups on the lower rim which leads to a neutral tecton. The combination of this p-tertbutyltetrathiacalix[4]arene (p-TCA-2), in 1, 3-alternate imposed conformation, with tetrahedral Ag(I)SbF6 salt, leads to the formation of neutral, new 2-D coordination network, which was structurally investigated in the solid state by X-ray diffraction methods on a single crystal.
Synthesis, Characterization, Computational Analyses, In Silico Admet Studies, And Inhibitory Action Against Sars-Cov-2 Main Protease (Mpro) Of A Schiff Base, Songül Şahi̇n, Necmi̇ Dege
Turkish Journal of Chemistry
COVID-19 disease caused by the severe acute respiratory syndrome coronavirus (SARS-CoV-2) has struck the whole world and raised severe health, economic, and social problems. Many scientists struggled to find a vaccine or an antiviral drug. Eventually, both vaccines and recommended drugs, repurposed drugs, or drug combinations were found, but new strains of SARS-CoV-2 continue to threaten human life and health. As part of the fight against COVID-19 disease, this study involves an in silico molecular docking analysis on the main protease (Mpro) of SARS-CoV-2. To this aim, a Schiff base compound was synthesized and characterized using spectroscopic techniques, including X-ray, …
High-Efficiency Removal Of Cationic Dye And Heavy Metal Ions From Aqueous Solution Using Amino-Functionalized Graphene Oxide, Adsorption Isotherms, Kinetics Studies, And Mechanism, Meti̇n Çelebi̇, Eda Gökirmak Söğüt
Turkish Journal of Chemistry
GO-NH2 (amino functionalized graphene oxide) was synthesized by grafting (3-aminopropyl) triethoxysilane onto the surface GO (graphene oxide). The GO-NH2 with a higher surface area and many active sites was characterized and its effectiveness in removing Rhod B dye and Ni(II) ions from wastewater by adsorption was observed. The effects of pH, time, and strange ions on the adsorption efficiency were investigated. The equilibrium isotherm data confirmed that it fits the Langmuir and Freundlich isotherm models. GO and GO-NH2 exhibited high adsorption capacity (QM); 2500 (mg L-1) and 3333 (mg L-1) for …
Single And Selective Transport Of Zr(Iv) Ions With Trioctyl Amine Dissolved In Kerosene Using A Multidropped Liquid Membrane Technique, Fatma Tezcan, Ramazan Donat
Turkish Journal of Chemistry
It is very important to develop a process for selectively extracting Zr(IV) ions from the solution medium to produce zirconium metal used in industry and nuclear reactors. In this study, the parameters affecting the extraction of Zr(IV) ions were investigated using a multidropped liquid membrane (MDLM) system. Trioctyl amine (TOA) dissolved in kerosene was used as a carrier ligand in the extraction of Zr(IV) ions by the MDLM technique. The effect of carrier concentration and stripping solution concentration, pH, and the temperature in the donor phase on the transport of Zr(IV) were investigated. The optimum condition for the transportation of …
