Dentistry Commons^™

The Effects Of Decellularized Extracellular Matrix Derived From Jagged1-Treated Human Dental Pulp Stem Cells On Biological Responses Of Stem Cells Isolated From Apical Papilla, Suphalak Phothichailert

Chulalongkorn University Theses and Dissertations (Chula ETD)

Objective: Indirect Jagged1 immobilization efficiently activates canonical Notch signaling in hDPSCs. This study aimed to investigate the characteristic of the Jagged1-treated hDPSCs-derived dECM and its biological activity on odonto/osteogenic differentiation SCAPs. Methods: Bioinformatic database of Jagged1-treated hDPSCs was analyzed by NetworkAnalyst. hDPSCs seeded on Jagged1 immobilized surface were maintained with N or OM followed by decellularization procedure, dECM-N or dECM-OM, respectively. SCAPs were reseeded on each dECM with either normal medium or OM. Cell viability was determined by MTT assay. Characteristics of dECMs and SCAPs were evaluated by SEM, EDX, immunofluorescent staining and alcian blue staining. A Multipotential differentiation assay. …

Effects Of The Orthodontic Miniscrew Geometric Design On The Bone Microdamage And Primary Stability, Panida Methawit

Chulalongkorn University Theses and Dissertations (Chula ETD)

This study investigated the effects of the pitch (P) and thread shape on orthodontic miniscrew cortical bone microdamage. The relationship between microdamage and primary stability was examined. Ti6Al4V orthodontic miniscrews had custom-made thread heights (H) and pitch sizes and were classified into the following groups: HCPC (control); HCPN (with a narrower pitch); and HTPC (with a taller thread height) (HC = 0.12 mm; HT = 0.36 mm; PC = 0.60 mm; PN = 0.30 mm). The orthodontic miniscrews were inserted in the pilot hole of prepared 1.0-mm-thick tibia cortical bone, and the maximum insertion torque (MIT) and Periotest value (PTV) …

Expression Of Superoxide Dismutase 3 (Sod3) During Orthodontic Tooth Movement In Rats, Phanchanit Jindarojanakul

Chulalongkorn University Theses and Dissertations (Chula ETD)

Hypoxia induces reactive oxygen species (ROS) production in periodontal tissues. Superoxide dismutase 3 (SOD3) is an enzyme protecting cells from ROS. This study investigated SOD3 expression and function during rat orthodontic tooth movement (OTM) and in hypoxia-exposed rat PDL cells. OTM of right maxillary first molars were performed in Sprague-Dawley rats for 1 and 14 days (n = 6 per group). SOD3 and HIF-1α expression were evaluated by immunohistochemistry. SOD3 effects on cell viability and proliferation, ROS production, and mRNA expression of Hif-1α, Rankl, and Opg in PDL cells and osteoclast differentiation were investigated under normoxia and hypoxia. SOD3 expression …

The Effect Of Nano-Silver Fluoride In Remineralization On Artificial Dentine Caries: An In Vitro Study, Peeraya Punpeng

Chulalongkorn University Theses and Dissertations (Chula ETD)

The aim of this in vitro study was to compare the remineralization efficiency among Nano-silver fluoride 400 ppm (NSF400), 38% Silver diamine fluoride (38% SDF) and 5% Sodium fluoride (5% NaF) on artificial dentine caries in permanent molar or premolar teeth. The teeth were sectioned to obtain 120 specimens (3 x 3 x 2 mm3). After artificial caries were created, the lesion depth (LD) was measured using Micro-computed tomography (Micro-CT) (n=15 specimens/group), and the surface microhardness (SMH) was measured using a Knoop microhardness tester (n=15 specimens/group). Subsequently, all specimens were randomly assigned to four groups: Group 1) NSF400, Group 2) …

Protein Expression After Gingival Injection Of Messenger Rna Encoding Platelet-Derived Growth Factor-Bb In Ligature-Induced Rat Periodontitis, Pimphorn Meekhantong

Chulalongkorn University Theses and Dissertations (Chula ETD)

As a new class of medicines, mRNA platform has proven to be safe and effective. The objective of this study was to investigate the effect of local inflammation on platelet derived growth factor-BB (PDGF-BB) expression after gingival injection of PDGF-BB mRNA in lipid nanoparticles (LNPs) in ligature-induced rat periodontitis and to examine the dose-dependent effect of gingival delivery of mRNA. 3-0 silk was placed around maxillary left second molar for two weeks and removed, while the corresponding molar on the right was non-ligated. Under stereomicroscope, a significant bone loss at ligature sites was observed as compared to the non-ligature sites, …

Comparison Of Compressive Strength Between Two Mini Implants :An In Vitro Study, Anchisa Weerasubpong

Chulalongkorn University Theses and Dissertations (Chula ETD)

Objective: To observe and evaluate the difference in static and dynamic loadings between two mini-implant systems (RetenDent and MS denture® system, OSSTEM). Materials and Methods: Fifty mini-implant from two companies were included in the study. The compressive force was applied to the mini-implants at 30 degrees from its vertical axis. Ten specimens from each group were subjected to static load tests. Subsequently, five cyclic loadings were calculated from static compressive strength. These loads include 320N, 275N, 230N, 185N, and 140N. Three specimens from each group were randomly selected and tested at each loading condition. The Independent T- test was utilized …

Alteration In Facial Contour Associated With Aging: Case Report, Bohan Lin Ba, Dds, Louis Mandel Dds

The New York State Dental Journal

The authors examined a 73-year-old female because of a chief complaint of bilateral swellings of the parotid gland. After detailed questioning, the authors determined that the perceived facial swelling was caused by the inferior displacement of separate and identifiable facial fat compartments. Aging coupled with gravity results in both a compartmental and intracompartment inferior displacement of facial fat. Long-lasting fillers injected intra-or extra-compartmentally also partake in this inferior migration.

Body Posture Evaluation Of Dental Specialty Groups And Risk Of Developing Musculoskeletal Disorders, Fatemeh Jahanimoghadam, Naimeh Hasheminejad, Naser Hashemi-Nejad

Journal of Dentistry Indonesia

Objective: Adopting correct body postures is extremely essential in preventing future musculoskeletal disorders in Dentists. The aim of this study was to evaluate the body posture of general and specialist dentists to find awkward body postures, badly postured body parts and the risk of developing future MSDs. Methods: Stratified sampling method was used to recruit 224 dentists in Kerman and Mashhad. The most frequently adopted body posture was selected and based on Rapid Entire Body Assessment (REBA) method, scores were given to the angulation of different body parts. T-test and ANOVA test were performed to analyze the data. Results: …

The Relationship Of Facial Measurements With The Mesiodistal Width Of The Maxillary Anterior Teeth, Nur Ilyana Aifa Aziz, Nadia Che Mohd, Izyan Hazwani Baharuddin, Aiemeeza Rajali, Tong Wah Lim, Su Keng Tan, Rohana Ahmad

Journal of Dentistry Indonesia

The relationship between facial measurements and the size of the maxillary anterior teeth in the Malaysian population is still a point of contention. Objective: The purpose of this study was to establish a relationship between facial measurements and the mesiodistal width of the maxillary anterior teeth (MDW), which could be used to guide the selection of anterior teeth for complete denture construction. Methods: The facial and dental measurements were obtained directly from 170 Malay adults aged between 19 to 35 who had morphologically normal permanent maxillary anterior teeth from canine to canine. The facial dimensions measured were interpupillary distance (IPD), …

Gender Differences In Academic Productivity Within Pediatric Dentistry Departments In Turkey, Basak Kiziltan Eliacik, Meltem Karahan

Journal of Dentistry Indonesia

Objective: To investigate the differences in the academic productivity of male and female academicians from the departments of pediatric dentistry in the Faculties of Dentistry in Turkey. Methods: A search was made of international studies indexed in PubMed published up until January 2021 by a total of 241 academicians in the Departments of Pediatric Dentistry of 79 Faculties of Dentistry in Turkey. The total number of international publications for each faculty member was obtained from the institutional websites and thorough searches of PubMed and Web of Science. H-index and the number of citations were established through an advanced search of …

Antibacterial And Antibiofilm Efficacy Of Pineapple Hump (Ananas Comosus) On Porphyromonas Gingivalis In Vitro, Abdul Gani Soulissa, Billy Lombardo, Armelia Sari Widyarman

Journal of Dentistry Indonesia

Background: Periodontal disease is one of the most prevalent oral health problems in Indonesia that affects supporting tissues of the teeth. Porphyromonas gingivalis plays an important role in the pathogenesis of periodontal disease. Alternative therapy with natural plant extracts, including pineapple (Ananas comosus) hump extract may inhibit the growth of bacteria that cause periodontal disease. Objective: To determine the effect of pineapple hump extract on bacterial growth and adhesion of Porphyromonas gingivalis biofilms. Method: The bacterial inhibition test was performed by the agar well diffusion method, and biofilm density measurements were made using the biofilm assay method. Results: Pineapple hump …

Hydrophobically Modified Isosorbide Dimethacrylates As Biomaterials For Bisphenol A Free Dental Fillings, Bilal Marie

Dissertations

Amalgam and Bisphenol A glycerolate dimethacrylate (BisGMA) are the main dental filling materials in use today. Because of the negative perception of amalgam and its lower esthetic appeal, as well as the desire to replace the endocrine disruptor Bisphenol A, which is the building block of BisGMA, there has been a critical need to search for safer alternatives to these dental filling materials.

Isosorbide is a sugar-based molecule generally recognized as safe. It has been extensively studied as a replacement to the Bisphenol A core in various materials. However, isosorbide is extremely hygroscopic, and water uptake in dental fillings causes …

Comparison Of Surface Roughness And Microhardness Of Reinforced Glass Ionomer Cements And Microhybrid Composite, Seda Nur Karakaş, Hacer Turgut, Cihan Küden

Journal of Dentistry Indonesia

Objectives: The purpose of this study was to compare high viscosity glass ionomer cement (HVGIC), giomer and microhybrid composite using the atomic force microscopy (AFM) and Vickers microhardness. Methods: Three different restorative materials Equia Forte (HVGIC), Beautifil II (giomer) and Solare X (microhybrid composite) were used in this study. A total of 30 samples were prepared, 10 of each of the restorative materials used in our study. Samples were prepared using standard cylindrical Teflon molds with a diameter of 8 mm and a height of 2 mm. The measurements of surface roughness and hardness were performed by using AFM and …

Management Of Severe Dento-Alveolar Traumatic Injuries In A 9-Year Old Boy: A Case Report, Elnaz Mousavi, Masoomeh Khoshdel, Hamidreza Sharifiyan

Journal of Dentistry Indonesia

Dentoalveolar traumas can lead to various injuries that may result in tooth loss. A suitable treatment plan and appropriate interventions should be performed to maintain the dental function and aesthetics, especially for the anterior teeth. Objective: To report the interventions performed on dentoalveolar trauma on a 9-years old male patient who presented with gingival immersion of the right maxillary central incisor and missing a tooth due to a falling accident. Case Report: The patient had multiple traumatic injuries. The medical and dental history was taken, and the clinical and radiologic examinations were performed. The patient underwent surgical intervention and splinting …

Replacement Of Two Failed Indirect Restorations With Direct Bonded Restorations Using Minimally Invasive Strategy, Citra Kusumasari, Takashi Hatayama, Yasushi Shimada

Journal of Dentistry Indonesia

Deciding on what treatment (repair or replacement) to provide for a failed indirect restoration can be challenging. Notably, the strength of the residual tooth structure could be improved after replacing the failed indirect restoration using a minimally invasive strategy. Objective: To describe the use of a minimally invasive strategy for the successful clinical replacement of two failed indirect metal restorations with direct composite restorations and the attainment of bonded restoration. Case Report: Case 1. A 52-year-old male patient came to the dental hospital complaining of discomfort when drinking cold beverages and food impaction on the proximal area of the upper …

Effects Of Different Finishing Procedures On Surface Roughness Of Hybrid Cad/Cam Materials, Ender Akan, Ozlem Colgecen, Ibrahim Talha Meşe, Bora Bağiş

Journal of Dentistry Indonesia

Hybrid ceramics combine the beneficial properties of resin with the advantage of glass ceramics. However, there are limited study about on roughness properties of hybrid materials. Objective: To investigate of the effects of surface finishing methods on roughness of dental restorations made from hybrid CAD/CAM blocks. Methods: A total of 60 samples were produced (n=20) for three main material groups, two different hybrid ceramic (LAVA Ultimate and VITA Enamic) and a conventional glass ceramic (IPS e.max CAD). Each material group was divided into two subgroups (n=10). Ten samples were polished and 10 were glazed according to related manufacturer instructions. Surface …

The Effect Of Parabiotic Reuterin On The Expression Of Genes Involved In Candida Albicans Biofilm Formation: An Ex Vivo Study, Anastasya Muna Riad, Armelia Sari Widyarman

Journal of Dentistry Indonesia

Candida albicans has a number of properties, including resistance to various antimicrobial agents, which allow it to survive in the root canals. Lactobacillus reuteri plays a role in maintaining oral health through interactions with the oral microbiome. L. reuteri has potential as a preventive and therapeutic agent against inflammatory diseases. Objective: The aim of this study was to investigate the effect of irrigation with a reuterin-containing solution on BCR1, ACE2, EFG1, and TEC1 gene expression in C. albicans root canal biofilms. Methods: L. reuteri was cultured in MRS broth and incubated anaerobically for 24 hours at 37°C. C. albicans was …

Financial Implication Of Covid-19: A Story Of Malaysian Dental Practitioner, Nor Faharina Abdul Hamid, Azlan Jaafar, Nurul Haini Najwa Mohamd Mahmod, Raja Nur Nabiha Raja Amir Hamzah

Journal of Dentistry Indonesia

Coronavirus disease 2019 (COVID-19) has caused series of lockdown in Malaysia which led to the significant financial impact to dental practitioner in Malaysia. Objectives: The aim of this study is to investigate factors affecting dental practice and its implication to financial situation during the pandemic in Malaysia. Methods: Registered Malaysian dental practitioners were invited to participate in online questionnaire via google form. Descriptive and Pearson’s chi-square test analysis were conducted (p<0.05). Results: 468 of dental practitioners had responded to our survey. More than three-quarter of dental practitioners worked in government sectors while almost a quarter worked in private sectors. 49.2% …

Association Among Hscrp Levels, Bone Mineral Density, And Periodontal Parameters In Postmenopausal Women, Aastha Baldodia, Rajinder Kumar Sharma, Shikha Tewari, Aman Arora

Journal of Dentistry Indonesia

Association of Osteoporosis and periodontitis is well documented. Osteopenia being the initial state of bone loss prior to osteoporosis; finding its correlation with clinical attachment loss holds significance in the process of establishing early reduction in BMD as a risk factor for periodontitis. Objectives: The present cross sectional study aimed to explore the association of osteopenia with serum high sensitivity C-reactive protein (hsCRP) levels, and periodontal parameters in narrow age range postmenopausal (PM) women. Methods: 112 participants in this single centred cross sectional study were bifurcated into test group: osteopenic PM women [n=62], and control group: normal bone mineral density …

Ectodermal Dysplasia: A Review, Yasemin Yavuz, Mehmet Sinan Doğan, Myroslav Goncharuk-Khomyn

Makara Journal of Health Research

Background: Ectodermal dysplasia is a complex group of genetic disorders identified through the abnormal development of ectodermal structures. It is a genetic disorder that affects the development or functions of tissues such as the teeth, hair, nails, and sweat glands.

Methods: This review aimed to introduce the outcomes and increase awareness of ectodermal dysplasia reviewing by the literature.

Results: The characteristic features of this disease, including hypodontia, hypohidrosis, and hypotrichosis, have been discussed.

Conclusions: Ectodermal dysplasia is a heterogeneous group of hereditary disorders with similar clinical findings. It leads to the development of tissue malformations and …