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Commentary: Phytocannabinoids As Therapeutic Agents To Combat Chronic Gingival Disease., Nick Narek Ohanian 2020 Arthur A. Dugoni School of Dentistry University of the Pacific

Commentary: Phytocannabinoids As Therapeutic Agents To Combat Chronic Gingival Disease., Nick Narek Ohanian

Pacific Journal of Health

The therapeutic potential of cannabis has been harnessed for thousands of years yet the United States Food and Drug Administration (FDA) has still not approved cannabis as a safe or effective drug. The FDA has, however, approved the manufacturing of pharmaceutical drugs, which contain a “synthetic version of a substance that is present in the marijuana” and other compounds that mimic its action. A search of the US National Library of Medicine and National Institute of Health for keywords “CBD” and “Periodontitis” together yields only 2 publications. Although the current State and Federal regulations on the use of cannabis for ...


Differential Diagnosis And Histopathological Analysis Of Localized Gingival Overgrowths: Study Of 218 Cases From Northeast Thailand, Lordjie Marr Morilla, Ajiravudh Subarnbhesaj, Poramaporn Klanrit 2020 Department of Clinical Dental Health Sciences, College of Dentistry, University of the Philippines, Manila

Differential Diagnosis And Histopathological Analysis Of Localized Gingival Overgrowths: Study Of 218 Cases From Northeast Thailand, Lordjie Marr Morilla, Ajiravudh Subarnbhesaj, Poramaporn Klanrit

Journal of Dentistry Indonesia

Localized gingival overgrowths (LGOs) are relatively common clinical findings. These lesions can be associated with chronic irritation, infections, or they can represent benign or malignant tumors that can either be primary or metastatic. The etiology of these lesions is multifactorial, but the most prevalent cause is reactive hyperplasia and inflammation induced by dental plaque. Objective: This study presents the prevalence of LGOs in Northeast Thailand and identifies the most common LGOs in the region. Methods: A series of 218 LGO cases was studied. Results: Pyogenic granuloma (PG), gingival squamous cell carcinoma (GSCC), and peripheral ossifying fibroma (POF) were the three ...


Evaluation Of Clinical Single Dental Implants Made Between 2013 And 2017, Zozan Erdoğmuş 2020 Ministry of Health, Diyarbakır Oral and Dental Health Hospital, Diyarbakır, Turkey

Evaluation Of Clinical Single Dental Implants Made Between 2013 And 2017, Zozan Erdoğmuş

Journal of Dentistry Indonesia

Objective: This retrospective study aimed to determine the profile of patients who underwent single tooth implants between 2013 and 1017 and to evaluate long-term follow-up and success. Methods: The results of 79 patients who underwent single dental intra-bone dental implantation in Diyarbakır Oral and Dental Health Hospital between 2013 and 2017 were evaluated separately in terms of gender, age, implanted area and number, systemic diseases affecting implant health, and missing implants. Results: In this study, single tooth implants were evaluated in 79 patients with a mean age of 39.55 years in men and 30.44 years in women. The ...


Demographic And Clinical Profile Of Gingival Oral Lichen Planus In A Group Of Thai Individuals, Pissacha Daroonpan, Ruchadaporn Kaomongkolgit, Weeraya Tantanapornkul, Jadesada Palasuk 2020 Department of Oral Diagnosis, Faculty of Dentistry, Naresuan University, Phitsanulok 65000, Thailand

Demographic And Clinical Profile Of Gingival Oral Lichen Planus In A Group Of Thai Individuals, Pissacha Daroonpan, Ruchadaporn Kaomongkolgit, Weeraya Tantanapornkul, Jadesada Palasuk

Journal of Dentistry Indonesia

Objective: This study aimed to determine the clinical profile of the gingival lesions of oral lichen planus (OLP) in a group of Thai patients. Methods: The dental records of 67 patients were reviewed. Results: In this study, 51 (76.1%) women and 16 (23.9%) men with a female-to-male ratio of 3.2:1 were included. The average age of patients with OLP was 56.0 ± 12.5 years (ranged = 20–81 years). Furthermore, 52 (77.6%) patients had a history of systemic diseases, and hypertension was predominant. All the patients presented with symptomatic OLP. Multiple OLP lesions were observed ...


Health-Related Anxiety In The Management Of Oral Soreness In An Hivseropositive Patient, Masita Mandasari, Zulvia Oktanida Syarif, Febrina Rahmayanti 2020 Oral Medicine Residency Program, Faculty of Dentistry, Universitas Indonesia, Jakarta, Indonesia

Health-Related Anxiety In The Management Of Oral Soreness In An Hivseropositive Patient, Masita Mandasari, Zulvia Oktanida Syarif, Febrina Rahmayanti

Journal of Dentistry Indonesia

The number of people living with HIV (PLHIV) has been increasing since the first known case in the early 1980s. However, PLHIV can also experience comorbidities, such as health anxiety. In the oral cavity, anxiety is often associated with the etiology of parafunctional habits. Anxiety can be measured using self-administered instruments, such as the Hospital Anxiety and Depression Scale (HADS) and Short-Health Anxiety Inventory (SHAI), which is specifically used in the medical setting. Objectives: We are describing a case of HIV positive patient with health anxiety who presented to the oral medicine clinic in our hospital with a complaint of ...


Oral Care Practices Of Adults In Turkey, Merve Koseoglu, Ozge Bal, Hatice Bilge Turkan, Beyza Cetin, Muhammed Nuri Tascioglu, Nurullah Aydin, Ozgur Sancar, Selma Altindis 2020 Department Prosthetic Dentistry, Faculty of Dentistry, Sakarya University, Sakarya, Turkey

Oral Care Practices Of Adults In Turkey, Merve Koseoglu, Ozge Bal, Hatice Bilge Turkan, Beyza Cetin, Muhammed Nuri Tascioglu, Nurullah Aydin, Ozgur Sancar, Selma Altindis

Makara Journal of Health Research

Background: Information on oral health practices can play a key role in improving a community’s oral health status. The aim of this study was to determine oral healthcare practices of Turkish individuals.

Methods: A questionnaire was randomly given to 351 individuals, all of them older than 18 years. This cross-sectional study data were analyzed using descriptive statistical methods and chi-square test. Statistical significance was evaluated at p < 0.05.

Results: According this study, 62.1% of individuals visited the dentist only when they needed to. Furthermore, 58% of individuals brushed their teeth twice a day; 12.5% of them used miswak ...


The Effects Of Exosomes On The Regeneration Of Rat Calvaria, Jill T. Beitz 2020 Virginia Commonwealth University

The Effects Of Exosomes On The Regeneration Of Rat Calvaria, Jill T. Beitz

Theses and Dissertations

Periodontal disease is a bacterial induced chronic inflammatory condition that occurs in a susceptible host, affecting the teeth, gingiva, periodontal ligament, and alveolar bone. The resultant pathological bone defects often require surgical intervention, with the ultimate goal being regeneration of the periodontium through the application of grafting materials and biologics. Mesenchymal stem cells (MSCs) show great potential in regenerative medicine for their ability to enhance cell proliferation and differentiation, increase angiogenesis, and modulate the immune response. Stem cell-derived by-products, known as exosomes are a specific class of lipid-membrane-bound extracellular vesicles that are proliferative and chemotactic, are able to inhibit cytokine ...


Characteristics Of Alveolar Bone Marrow Cells From Patients Undergoing Dental Extractions Or Dental Implant Therapy, Meng H. Lee 2020 Virginia Commonwealth University

Characteristics Of Alveolar Bone Marrow Cells From Patients Undergoing Dental Extractions Or Dental Implant Therapy, Meng H. Lee

Theses and Dissertations

Alveolar bone marrow stromal cells (aBMSCs) play important roles in craniofacial wound healing. To establish an easy, efficient and reliable method to harvest aBMSCs, we compared three different methods: extraction socket aspiration, osteotomy aspiration and bone core digestion. Samples of aBMSC were collected from two groups of subjects. Group 1 (dental extraction): after dental extraction, 22.5-gauge needles were used to collect 0.5-1cc marrow aspirate. Group 2 (dental implant): during implant surgeries, bone core and 0.5-1cc marrow aspirate were obtained from the osteotomy. Samples were cultured in petri dishes and attached cells were expanded. The population doubling time ...


Accuracy Of Blx And Blt Guided Implants In The Edentulous Maxilla: An In Vivo Study, Benjamin Andrew Kordusky 2020 West Virginia University

Accuracy Of Blx And Blt Guided Implants In The Edentulous Maxilla: An In Vivo Study, Benjamin Andrew Kordusky

Graduate Theses, Dissertations, and Problem Reports

Objectives: To determine the accuracy of dental implants placed using a dual scan CBCT protocol with a SLA 3D printed mucosa supported surgical guide using a flapless surgical approach with regard to sleeve position, type of implant, and regional location in the maxillary arch.

Methods: Nine patients received 4 dental implants utilizing a fully guided, flapless approach with a mucosa supported SLA surgical guide with 3 fixation pins. Implants were immediately loaded using an attachment placed in an existing Maxillary complete denture. Accuracy of implant positions were evaluated by the Treatment Evaluation module of coDiagnostiX (DentalWings, Montreal, Canada). Statistical analysis ...


Tobacco Cessation In A Dental School Setting, Kerri T. Simpson 2020 West Virginia University

Tobacco Cessation In A Dental School Setting, Kerri T. Simpson

Graduate Theses, Dissertations, and Problem Reports

Introduction

Tobacco use remains the single largest preventable cause of death in the United States. Currently, the prevalence of tobacco use is 20.7% in adults (≥18 years old) and 31.2% among high school students. According to various studies, over 60% of Americans want to quit tobacco, but it takes a person several attempts to quit before they are successful. There is limited data in the literature that discusses the effectiveness of tobacco cessation programs in US dental schools. Therefore, information on the effectiveness of a tobacco cessation program in a dental school setting could benefit this state and ...


Antimicrobial Efficacy Of Myrmecodia Pendens Extract And Fraction Combination Against Enterococcus Faecalis Atcc 29212, Faisal Kuswandani, Mieke H. Satari, Ani M. Maskoen 2019 Biomedical Science Master Program, Faculty of Medicine, Universitas Padjadjaran, Bandung, West Java 45363, Indonesia

Antimicrobial Efficacy Of Myrmecodia Pendens Extract And Fraction Combination Against Enterococcus Faecalis Atcc 29212, Faisal Kuswandani, Mieke H. Satari, Ani M. Maskoen

Journal of Dentistry Indonesia

Enterococcus faecalis can withstand harsh environmental conditions in the root canal and cause a secondary infection. Myrmecodia pendens is an herbal medicine rich in polyphenol compounds that have antibacterial, antioxidant, and anticancer properties. Objectives: To analyze the effects of M. pendens fraction combination on the sensitivity of E. faecalis. Methods: The minimum inhibitory concentration (MIC) was determined using a serial microdilution method, and the minimum bactericidal concentration (MBC) was determined by adding the test sample to sterile Mueler Hinton agar medium. Results: The MIC of combination 1 (hexane-ethyl acetate, HE) was 0.049 mg/mL, whereas those of combinations 2 ...


Hazards Of Short- And Long-Term Administration Of Glucocorticoids On The Periodontium In Rats: A Histological And Electron Microscopic Study, Tahani Abd El Karim Hagag, Elham Fathy, Mahmoud Fathy Mahmoud, zeinab salem 2019 Department of Oral Biology, Faculty of Dentistry, Cairo University, 12613, Egypt

Hazards Of Short- And Long-Term Administration Of Glucocorticoids On The Periodontium In Rats: A Histological And Electron Microscopic Study, Tahani Abd El Karim Hagag, Elham Fathy, Mahmoud Fathy Mahmoud, Zeinab Salem

Journal of Dentistry Indonesia

The administration of glucocorticoids is proven to cause serious adverse events. Objectives: This study was conducted to compare the possible hazards of the short- and long-term administration of glucocorticoids on the periodontium in rats, using histological examination and scanning electron microscopy. Methods: Fifteen adult male albino rats were included in the study and divided into the 3 groups. Group I served as a control, group II received 7 mg/kg dexamethasone intramuscularly once a week for 5 wk, and group III received 7 mg/kg dexamethasone intramuscularly once a week for 10 wk. The mandibles were dissected and examined histologically ...


Persistent Endodontics Pathogens Biofilm Inhibited By Lactobacillus Reuteri Indonesian Strain, Armelia Sari Widyarman, Njoo Kiky Elysia Lazaroni 2019 Department of Microbiology, Faculty of Dentistry, Trisakti University, Jakarta, 11440 Indonesia

Persistent Endodontics Pathogens Biofilm Inhibited By Lactobacillus Reuteri Indonesian Strain, Armelia Sari Widyarman, Njoo Kiky Elysia Lazaroni

Journal of Dentistry Indonesia

Lactobacillus reuteri is known as probiotics that effective to improve oral health. Objective: To analyze the effect of L. reuteri Indonesian strain, towards Enterococcus faecalis and Candida albicans biofilm growth. Methods: This study was conducted using biofilm assay. Each E. faecalis ATCC-29212 and C. albicans ATCC-10231 were cultured in Brain Heart Infusion Broth, distributed into 96 well-microplate and incubated for 24h, 37°C, anaerobic condition for E. faecalis and aerobic condition for C. albicans. L. reuteri LC382415 (Indonesian strain) was cultured in deMann Rogosa Shar pe Broth and diluted into different concentrations (108,106, and 104CFU ...


Orthodontic Camouflage Treatment Of A High-Angle Severe Skeletal Class Ii Discrepancy, Deryana Marshadhianti, Miesje Karmiati Purwanegara 2019 Orthodontics Residency Program, Faculty of Dentistry, Universitas Indonesia, Jakarta, 10430 Indonesia

Orthodontic Camouflage Treatment Of A High-Angle Severe Skeletal Class Ii Discrepancy, Deryana Marshadhianti, Miesje Karmiati Purwanegara

Journal of Dentistry Indonesia

Proper orthodontic treatment in adult patients with severe skeletal Class II discrepancy can be challenging. Recently, miniscrew implants have been used as a strategy to treat skeletal Class II patients. Objective: This report illustrates a skeletal Class II malocclusion management combining straight wire technique and miniscrew implant anchorage. Case report: The patient was a 21-years- old Indonesian female with Class II skeletal discrepancy, a retrognathic mandible, a high mandibular plane angle, and a mouth breathing habit due to a history of allergic rhinitis. Anchorage control is important in the sagittal and vertical directions. Miniscrew implants were placed in the interradicular ...


Gingival Mscs Improve Bone Phenotype In Ovariectomy-Induced Osteoporosis Via Programmed Cell Death Pathway, Sultan Alghaithi 2019 University of Pennsylvania

Gingival Mscs Improve Bone Phenotype In Ovariectomy-Induced Osteoporosis Via Programmed Cell Death Pathway, Sultan Alghaithi

Dental Theses

Estrogen deficiency-related osteoporosis is a skeletal system disorder that affects women after menopause taking a toll on financial and health institutions. Gingival Mesenchymal Stem cells (GMSCs) are a distinctive population of dental tissue-derived stem cells that possess uniquely high proliferation abilities and are capable of self-maintenance and multipotent differentiation. Their use has been investigated in different disease model applications, including cutaneous wound healing models, colitis, and allergy-related inflammatory disease models, but their effect on the bone phenotype of ovariectomy-induced osteoporosis hasn’t been explored. In our study, we show that a single systemic infusion of GMSCs elevated the bone mass ...


Dental Implant Failure Rate And Marginal Bone Loss In Smokers Compared To Non-Smokers: A Systematic Review And Meta-Analysis, Mohammad S. Akel 2019 University of Pennsylvania

Dental Implant Failure Rate And Marginal Bone Loss In Smokers Compared To Non-Smokers: A Systematic Review And Meta-Analysis, Mohammad S. Akel

Dental Theses

Background:Although dental implant therapy is considered a predictable treatment modality with reported high survival and success rates, biological complications do occur, and a number of risk factors have been involved. Tobacco smoking is related to many health risks affecting general & oral health.

Objectives: The aim of this systematic review and meta-analysis is to test the null hypothesis of no difference in dental implant failure rates and marginal bone loss between smokers and non-smokers with regards to follow-up time.

Search methods: An extensive electronic search was performed in PubMed, Scopus and EBSCOhost Dentistry and Oral Sciences source to identify relevant ...


Part I: Complete Dentures And Diabetes Correlation, Ibeth Erazo 2019 CUNY New York City College of Technology

Part I: Complete Dentures And Diabetes Correlation, Ibeth Erazo

Publications and Research

Diabetes is one of the most frequent pathologies that dentists encounter, due to its high prevalence worldwide. The aim of this study is to present the correlation between diabetes and complete denture wearers, intending to emphasize the importance of proper control and denture adaptation to oral environment for this type of patient. Within the sphere of the dental office, one of the main complications to consider in this type of patient is periodontal disease, which is their most frequent complication. Other important oral manifestations considered in the research are fungal infections, xerostomia, and burning mouth syndrome. It is common for ...


Epidemiologic Evaluation Of Nhanes For Environmental Factors And Periodontal Disease, P. Emecen-Huja, H-F Li, Jeffrey L. Ebersole, J. Lambert, H. Bush 2019 Medical University of South Carolina

Epidemiologic Evaluation Of Nhanes For Environmental Factors And Periodontal Disease, P. Emecen-Huja, H-F Li, Jeffrey L. Ebersole, J. Lambert, H. Bush

Dental Medicine Faculty Publications

Periodontitis is a chronic inflammation that destroys periodontal tissues caused by the accumulation of bacterial biofilms that can be affected by environmental factors. This report describes an association study to evaluate the relationship of environmental factors to the expression of periodontitis using the National Health and Nutrition Examination Study (NHANES) from 1999–2004. A wide range of environmental variables (156) were assessed in patients categorized for periodontitis (n = 8884). Multiple statistical approaches were used to explore this dataset and identify environmental variable patterns that enhanced or lowered the prevalence of periodontitis. Our findings indicate an array of environmental variables were ...


New Periodontal Pathogens And Their Biogeography In Ex Vivo Biofilms, Fany B. Ocampo 2019 University of Pennsylvania

New Periodontal Pathogens And Their Biogeography In Ex Vivo Biofilms, Fany B. Ocampo

Dental Theses

Background: About 35% of the oral microbiome remains uncultured due to limitations of conventional laboratory techniques. More than 200 of those phylotypes have been catalogued in the HOMD and a subset of them had been proposed as candidate periodontal pathogens. This segment of the microbiome merits further investigation, as it might harbor important pathogens that are currently overlooked. Objective: The objective of this study was to devise an imaging approach to study such phylotypes in the conditions most conducive to their growth and begin to unveil their ecological and biogeographical characteristics.

Methods: Previous work from the Teles Lab had identified ...


The Change Of Alveolar Bone Thickness On Mandibular Central Incisors Of Skeletal Class Ii Patients After Orthodontic Treatment Using Cone-Beam Computed Tomography., Kensuke Matsumoto, Scott Sherrill-Mix, Normand Boucher, Nipul Tanna 2019 University of Pennsylvania

The Change Of Alveolar Bone Thickness On Mandibular Central Incisors Of Skeletal Class Ii Patients After Orthodontic Treatment Using Cone-Beam Computed Tomography., Kensuke Matsumoto, Scott Sherrill-Mix, Normand Boucher, Nipul Tanna

Dental Theses

Objective: To test the null hypothesis that orthodontic tooth movement does not create dehiscences and the sagittal width dimension of alveolar bone is maintained. Materials and Methods: In 60 skeletal class II patients, CBCT images at pre- (T1) and post-orthodontic treatment (T2) were obtained and the presence of dehiscences was recorded. Based on the presence of dehiscences at T1 and T2, the patients were divided into four groups. The alveolar bone thickness at the level of 2 (CEJ2), 5 (CEJ5), 10 (CEJ10), and 15 (CEJ15) mm from the cementoenamel junction (CEJ) was measured on CBCT images in cross section along ...


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