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Oral and Maxillofacial Surgery Commons

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133 Full-Text Articles 153 Authors 9697 Downloads 17 Institutions

All Articles in Oral and Maxillofacial Surgery

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Mesenchymal Stem Cell (Msc) Spheroid Constructs Containing Microfluidic Bmp2-Plga Microcapsules In Bone Tissue Engineering., Bhavendrasinh Sayania 2017 University of Pennsylvania

Mesenchymal Stem Cell (Msc) Spheroid Constructs Containing Microfluidic Bmp2-Plga Microcapsules In Bone Tissue Engineering., Bhavendrasinh Sayania

Dental Theses

Recombinant human bone morphogenetic protein-2 (rhBMP-2) is a clinically available osteogenic growth factor. In its current form, approved for clinical use, however, the growth factor is delivered in excessively high doses, resulting in unpredictable bone growth and unwanted clinical side effects. In this study, we evaluated a novel system, slow-release hybrid delivery system for PLGA- rhBMP-2 microcapusles in combination with BM MSC spheroids, and assess if it can lead to improved BMP-derived bone formation. The first aim of this study is to evaluate the osteogenicity of 3D cell spheroids as compared to 2D cultured cells, as we used primary cells ...


Expression Of Human Tissue Kallikreins (Klks) In Polymorphous Low Grade Adenocarcinoma (Plga), Jacqueline M. Cox 2017 The University of Western Ontario

Expression Of Human Tissue Kallikreins (Klks) In Polymorphous Low Grade Adenocarcinoma (Plga), Jacqueline M. Cox

Electronic Thesis and Dissertation Repository

Polymorphous low grade adenocarcinoma (PLGA) is the second most common malignant salivary gland tumour of the minor salivary glands. Human tissue kallikreins (KLKs) are a family of highly conserved serine proteases expressed by various tissues throughout the body. KLKs have become powerful tumour markers for the diagnosis of the cancer patient (e.g. PSA (KLK3)). The literature demonstrates a link between KLKs and salivary gland neoplasms. The purpose of this study is to determine levels of KLK mRNA in tissue samples of formalin fixed paraffin embedded polymorphous low grade adenocarcinoma (PLGA). Secondly, we wish to determine if KLK expression is ...


Interview With Ralph Merrill, D.D.S., M.Sc.D., Ralph Merrill D.D.S., M.Sc.D. (interviewee), Louis G. Terkla D.M.D. (interviewer) 2017 Oregon Health & Science University

Interview With Ralph Merrill, D.D.S., M.Sc.D., Ralph Merrill D.D.S., M.Sc.D. (Interviewee), Louis G. Terkla D.M.D. (Interviewer)

Oral History Collection

Ralph Merrill, D.D.S., M.Sc.D., was born in Salt Lake City on December 24, 1932. He decided on a career in dentistry while studying at the University of Denver and during an externship at a Native American hospital in Alaska, his mentor's influence guided him into focusing on surgery. He attended the University of Washington School of Dentistry, completing residencies at Boston City Hospital, Boston University, and Henry Ford Hospital (Detroit). Merrill came to OHSU as he wished to work on the academic side of oral surgery and was particularly impressed with the ortho-pathology departments and ...


Orofacial Pain Overview: Getting Rid Of The Riddles, Andrew L. Young 2017 University of the Pacific

Orofacial Pain Overview: Getting Rid Of The Riddles, Andrew L. Young

Andrew L. Young

While most pains that find their way to the dental office are dental in origin, some have less familiar roots: muscular, joint, neurological, headache, sinus or psychological. All of these roots can at times masquerade as a toothache. The purpose of this article is to alert the dentist to the select features of each root that distinguish it from the rest, resulting in efficient and appropriate treatment.


Authentic Leadership In Illness Blogs: What We Can Learn From Jaw Surgery Bloggers, Marilyn Mitchell 2016 Bond University

Authentic Leadership In Illness Blogs: What We Can Learn From Jaw Surgery Bloggers, Marilyn Mitchell

Faculty of Society and Design Publications

This paper argues that authentic leadership theory provides a useful model for explaining the communication of orthognathic or jaw surgery bloggers. Previous studies concluded that illness blogs can empower patients, but no research considered any leadership theory as a model for blogging. For this study, 24 publicly available blogs were analyzed to find expressions that demonstrated each of the four components of authentic leadership, which are self-awareness, relational transparency, communication based upon an internalized moral perspective, and balanced processing of information. The research also analyzed blog comments to find expressions that demonstrated followers’ development of the positive psychological capacities of ...


Orofacial Pain Overview: Getting Rid Of The Riddles, Andrew L. Young 2016 University of the Pacific

Orofacial Pain Overview: Getting Rid Of The Riddles, Andrew L. Young

Dugoni School of Dentistry Faculty Articles

While most pains that find their way to the dental office are dental in origin, some have less familiar roots: muscular, joint, neurological, headache, sinus or psychological. All of these roots can at times masquerade as a toothache. The purpose of this article is to alert the dentist to the select features of each root that distinguish it from the rest, resulting in efficient and appropriate treatment.


Analyzing The Regionalized Awareness Of Distraction Osteogenesis, Ali Weinzapfel 2016 Western Kentucky University

Analyzing The Regionalized Awareness Of Distraction Osteogenesis, Ali Weinzapfel

Honors College Capstone Experience/Thesis Projects

There are multiple treatment options available to initiate bone growth within the oral cavity. Distraction osteogenesis is a surgical dental procedure performed to initiate new bone growth in the maxillofacial region. This procedure is an important advancement to dental professionals because of the minimal complications and great outcome of bone growth it offers. As dentistry is always evolving, it is imperative to relay current trends to other professionals within the field of dentistry. The goal of this research was to analyze the regionalized awareness of distraction osteogenesis. A survey was conducted among dentists in Kentucky and Tennessee with multiple questions ...


Managing Peri-Implantitis, Namita Khandelwal 2016 University of New England

Managing Peri-Implantitis, Namita Khandelwal

Dental Medicine Faculty Publications

This guide, used by MetLife for its dental continuing education program, focuses on the inflammatory pathology around dental implants. It outlines the risk factors and diagnostic criteria for peri-implantitis, an inflammatory process resulting in progressive loss of bone around the implant. The guide also provides treatment approaches for peri-implantitis, including surgical and non-surgical options.


Longterm Quality Of Life After Oncologic Surgery And Microvascular Free Flap Reconstruction In Patients With Oral Squamous Cell Carcinoma, Andre Peisker, Gregor F. Raschke, Arndt Guentsch, Korosh Roshanghias, Francy Eichmann, Stefan Schultze-Mosgau 2016 Friedrich Schiller University of Jena

Longterm Quality Of Life After Oncologic Surgery And Microvascular Free Flap Reconstruction In Patients With Oral Squamous Cell Carcinoma, Andre Peisker, Gregor F. Raschke, Arndt Guentsch, Korosh Roshanghias, Francy Eichmann, Stefan Schultze-Mosgau

School of Dentistry Faculty Research and Publications

Background: Quality of life (QoL) has become increasingly important in cancer treatment. It refers to the patient’s perception of the effects of the disease and therapy, and their impact on daily functioning and general feeling of well being. Material and Methods: In this prospective study, a total of 100 patients treated at our institution, completed the European Organization for Research and Treatment of Cancer (EORTC) QLQ-C30 questionnaire and the specific EORTC QLQ-H&N35 module. The questionnaires were distributed to the patients between 12 and 60 months postoperatively. Results: Global QoL score was 58.3 and mean score for functioning ...


Wearing Complete Dental Prostheses - Effects On Perioral Morphology, Gregor F. Raschke, Philipp Eberl, Geoffrey A. Thompson, Arndt Guentsch, Andre Peisker, Stefan Schultze-Mosgau, Marta Gomez-Dammeier, Gabriel Djedovic, Ulrich M. Rieger, Florian Beuer 2016 Friedrich Schiller University of Jena

Wearing Complete Dental Prostheses - Effects On Perioral Morphology, Gregor F. Raschke, Philipp Eberl, Geoffrey A. Thompson, Arndt Guentsch, Andre Peisker, Stefan Schultze-Mosgau, Marta Gomez-Dammeier, Gabriel Djedovic, Ulrich M. Rieger, Florian Beuer

School of Dentistry Faculty Research and Publications

Background: To adequately perform rehabilitation of edentulous patients by a complete removable dental prosthesis (CRDP) is from basic interest to dentists to understand the morphologic changes caused by re-establishment of a physiologic jaw relationship. Anthropometric analyses of standardized frontal view and profile photographs may help elucidate such changes. Material and Methods: Photographs of 31 edentulous patients were compared in relaxed lip closure and after insertion of a CRDP in stable occlusion. 2232 anthropometric distances were raised. Eighteen anthropometric indices reflecting the perioral morphology and its integration in the vertical facial harmony were investigated. Results: The intercanthal – mouth width index (p<.001), medial – lateral cutaneous upper lip height index (p=.007), lower vermilion contour index (p=.022), vermilion – total upper lip height index (p=.018), cutaneous – total upper lip height index (p=.023), upper lip – nose height index (p=.001), nose – upper face height index (p=.002), chin – mandible height index (p=.013), upper lip – mandible height index (p=.045), nose – lower face height index (p=.018), and nose - face height index (p=.029) showed significant pre- to post-treatment changes. Conclusions: The investigated anthropometric indices presented reproducible results related to an increase in occlusal vertical dimension. Their application may be helpful in assessment, planning, and explanation of morphologic effects of CRDPs on the perioral and overall facial morphology, which may helps to improve the aesthetic outcome.


Perception Of Differences In Lip Profile Between 2-D And 3-D, Andrew Hansen 2016 Virginia Commonwealth University

Perception Of Differences In Lip Profile Between 2-D And 3-D, Andrew Hansen

Theses and Dissertations

Past studies evaluating the esthetics of orthodontic treatment have been done using 2-D images. New 3-D imaging offers an improved, real-life representation of a subject. The purpose of this study was to determine how laypeople perceived differences in lip position (flat versus ideal lip fullness) in 2-D compared to 3-D.

3dMD images of 8 Caucasian subjects were adjusted to an ideal and flat lip position in 3-D and then in 2-D from the profile view. 2 surveys were created with paired ideal and flat images on the screen, either in 2-D or 3-D, and evaluators were asked to choose which ...


Dental Extraction Is Probably Safe For Patients With Thrombocytopenia: The Standard Of Care Is A Guide For Clinical Decision Making Related To Platelet Transfusion., Phillip So 2015 Wayne State University School of Medicine

Dental Extraction Is Probably Safe For Patients With Thrombocytopenia: The Standard Of Care Is A Guide For Clinical Decision Making Related To Platelet Transfusion., Phillip So

Clinical Research in Practice: The Journal of Team Hippocrates

A critical appraisal and clinical application of Fillmore WJ, Leavitt BD, Arce K. Dental extraction in the thrombocytopenic patient is safe and complications are easily managed. J Oral Maxillofac Surg. 2013 Oct;71(10):1647-1652. doi:10.1016/j.joms.2013.05.011.


Clinical Outcomes Of Maxillomandibular Advancement Surgery For The Treatment Of Obstructive Sleep Apnea, Brian L. Phee 2015 The University of Western Ontario

Clinical Outcomes Of Maxillomandibular Advancement Surgery For The Treatment Of Obstructive Sleep Apnea, Brian L. Phee

Electronic Thesis and Dissertation Repository

Objective: To evaluate clinical and radiographic treatment outcomes after maxillomandibular advancement (MMA) surgery on subjects suffering from obstructive sleep apnea (OSA).

Materials and Methods: This was a retrospective cohort analysis. Subjects underwent pre- and post-surgical polysomnography (PSG) studies and were also asked to complete a subjective self-assessment via the Epworth Sleepiness Scale (ESS) questionnaire. Twenty-two patients (11 male, 11 female) met the inclusion criteria.

Results: The mean pre-surgical apnea-hypopnea index (AHI) score was 48.4 (+/-31.3) and mean ESS score was 11.6 (+/-4.6). After surgery, the mean AHI reduced to 14.0 (+/-15.0) and ESS reduced ...


Morphologic Outcome Of Bimaxillary Surgery–An Anthropometric Appraisal, Gregor F. Raschke, Ulrich M. Rieger, Andre Peisker, Gabriel Djedovic, Marta Gomez-Dammeier, Arndt Guentsch, Oliver Schaefer, Stefan Schultze-Mosgau 2015 Friedrich Schiller University of Jena

Morphologic Outcome Of Bimaxillary Surgery–An Anthropometric Appraisal, Gregor F. Raschke, Ulrich M. Rieger, Andre Peisker, Gabriel Djedovic, Marta Gomez-Dammeier, Arndt Guentsch, Oliver Schaefer, Stefan Schultze-Mosgau

School of Dentistry Faculty Research and Publications

Objectives: To adequately perform orthognathic surgery procedures, it is from basic interest to understand the morphologic changes caused by orthognathic surgery. Anthropometric analyses of standardized frontal view and profile photographs could help to investigate and understand such changes. Study Design: We present a pre- to postoperative evaluation of orthognathic surgery results based on anthropometric indices described by Farkas and cephalometric measurements. 30 Class III patients undergoing maxillary advancement by Le Fort I Osteotomy and mandibular setback by bilateral sagittal split osteotomy were evaluated. Preoperative as well as three and nine months postoperative lateral cephalograms as well as standardized frontal view ...


Are Pulp Sensibility Tests Still Sensible?, Huma Farid, Farhan Raza Khan, Lubna Pasha, Muhammad Saad Shinwari 2015 The Aga Khan University

Are Pulp Sensibility Tests Still Sensible?, Huma Farid, Farhan Raza Khan, Lubna Pasha, Muhammad Saad Shinwari

Section of Dental-Oral Maxillofacial Surgery

Background:

Electric and thermal tests are the most commonly employed methods for the diagnosis of pulp health status. The objectives of our study are to assess the validity, yield and accuracy of cold and electric pulp tests in determining pulp vitality of teeth requiring endodontic treatment.

Methods:

A cross sectional study was carried out at the Dental Clinic of Aga Khan University Hospital on 75 patients requiring endodontic treatment. Before commencement of endodontic treatment, a provisional diagnosis of pulp status was made using an electric pulp tester and cold test. The tooth was then labelled as either vital or necrotic ...


Bioerodible Calcium Sulfate Bone Grafting Substitutes With Tailored Drug Delivery Capabilities, Bryan R. Orellana 2014 University of Kentucky

Bioerodible Calcium Sulfate Bone Grafting Substitutes With Tailored Drug Delivery Capabilities, Bryan R. Orellana

Theses and Dissertations--Biomedical Engineering

Bone regeneration or augmentation is often required prior to or concomitant with implant placement. With the limitations of many existing technologies, a biologically compatible synthetic bone grafting substitute that is osteogenic, bioerodible, and provides spacing-making functionality while acting as a drug delivery vehicle for bioactive molecules could provide an alternative to ‘gold standard’ techniques.

In the first part of this work, calcium sulfate (CS) space-making synthetic bone grafts with uniformly embedded poly(β-amino ester) (PBAE) biodegradable hydrogel particles was developed to allow controlled release of bioactive agents. The embedded gel particles’ influence on the physical and chemical characteristics of CS ...


Antimicrobial Peptide Coating Of Dental Implants: Biocompatibility Assessment Of Recombinant Human Beta Defensin-2 For Human Cells, Patrick Warnke, Eske Voss, Paul Russo, Sebastien Stephens, Michael Kleine, Hendrik Terheyden, Qin Liu 2013 Griffith University

Antimicrobial Peptide Coating Of Dental Implants: Biocompatibility Assessment Of Recombinant Human Beta Defensin-2 For Human Cells, Patrick Warnke, Eske Voss, Paul Russo, Sebastien Stephens, Michael Kleine, Hendrik Terheyden, Qin Liu

Qin Liu

Purpose: Artificial materials such as dental implants are at risk of bacterial contamination in the oral cavity. Human beta defensins (HBDs), small cationic antimicrobial peptides that exert a broad-spectrum antibacterial function at epithelial surfaces and within some mesenchymal tissues, could probably help to reduce such contamination. HBDs also have protective immunomodulatory effects and have been reported to promote bone remodeling. The aim of this study, therefore, was to investigate the influence of recombinant HBD-2 on the proliferation and survival of cells in culture.

Materials and Methods: Human mesenchymal stem cells (hMSCs), human osteoblasts, human keratinocytes (control), and the HeLa cancer ...


Comparison Of In Vitro Biocompatibility Of Nanobone(®) And Biooss(®) For Human Osteoblasts, Qin Liu, Timothy Douglas, Christiane Zamponi, Stephan Becker, Eugene Sherry, Sureshan Sivananthan, Frauke Warnke, Jörg Wiltfang, Patrick Warnke 2013 Dept of Oral and Maxillofacial Surgery, Kiel, Germany

Comparison Of In Vitro Biocompatibility Of Nanobone(®) And Biooss(®) For Human Osteoblasts, Qin Liu, Timothy Douglas, Christiane Zamponi, Stephan Becker, Eugene Sherry, Sureshan Sivananthan, Frauke Warnke, Jörg Wiltfang, Patrick Warnke

Qin Liu

Introduction:Scaffolds for bone tissue engineering seeded with the patient's own cells might be used as a preferable method to repair bone defects in the future. With the emerging new technologies of nanostructure design, new synthetic biomaterials are appearing on the market. Such scaffolds must be tested in vitro for their biocompatibility before clinical application. However, the choice between a natural or a synthetic biomaterial might be challenging for the doctor and the patient. In this study, we compared the biocompatibility of a synthetic bone substitute, NanoBone®, to the widely used natural bovine bone replacement material BioOss®.Material and ...


Proliferation Assessment Of Primary Human Mesenchymal Stem Cells On Collagen Membranes For Guided Bone Regeneration, Qin Liu, A. Humpe, D. Kletsas, F. Warnke, S. Becker, T. Douglas, S. Sivananthan, P. Warnke 2013 Bond University

Proliferation Assessment Of Primary Human Mesenchymal Stem Cells On Collagen Membranes For Guided Bone Regeneration, Qin Liu, A. Humpe, D. Kletsas, F. Warnke, S. Becker, T. Douglas, S. Sivananthan, P. Warnke

Qin Liu

Purpose: Human mesenchymal stem cells (hMSCs) hold the potential for bone regeneration because of their self-renewing and multipotent character. The goal of this study was to evaluate the influence of collagen membranes on the proliferation of hMSCs derived from bone marrow. A special focus was set on short-term eluates derived from collagen membranes, as volatile toxic materials washed out from these membranes may influence cell behavior during the short time course of oral surgery.

Materials and Methods: The proliferation of hMSCs seeded directly on a collagen membrane (BioGide) was evaluated quantitatively using the cell proliferation reagent WST-1 (4-3-[4-iodophenyl]-2- ...


Protaper Rotary Instrument Fracture During Root Canal Preparation: A Comparison Between Rotary And Hybrid Techniques, Huma Farid, Farhan Raza Khan, Munawar Rahman 2013 Aga Khan University

Protaper Rotary Instrument Fracture During Root Canal Preparation: A Comparison Between Rotary And Hybrid Techniques, Huma Farid, Farhan Raza Khan, Munawar Rahman

Section of Dental-Oral Maxillofacial Surgery

AIMS:

This study aimed to compare the frequency of ProTaper rotary instrument fracture with rotary (conventional) and hybrid (rotary and hand files) canal preparation techniques. Secondary objectives were to determine whether there was an association of ProTaper file fracture with the canal curvature and to compare the mean time required for canal preparation in the two techniques.

METHODS:

An in vitro experiment was conducted on 216 buccal canals of extracted maxillary and mandibular first molars. After creating an access cavity and a glide path for each canal, a periapical radiograph was taken and the canal curvature was measured with Schneider ...


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