Statistics and Probability Commons^™

Software Internationalization: A Framework Validated Against Industry Requirements For Computer Science And Software Engineering Programs, John Huân Vũ

Master's Theses

View John Huân Vũ's thesis presentation at http://youtu.be/y3bzNmkTr-c.

In 2001, the ACM and IEEE Computing Curriculum stated that it was necessary to address "the need to develop implementation models that are international in scope and could be practiced in universities around the world." With increasing connectivity through the internet, the move towards a global economy and growing use of technology places software internationalization as a more important concern for developers. However, there has been a "clear shortage in terms of numbers of trained persons applying for entry-level positions" in this area. Eric Brechner, Director of Microsoft Development Training, suggested …

Targeting The Optimal Design In Randomized Clinical Trials With Binary Outcomes And No Covariate, Antoine Chambaz, Mark J. Van Der Laan

U.C. Berkeley Division of Biostatistics Working Paper Series

This article is devoted to the asymptotic study of adaptive group sequential designs in the case of randomized clinical trials with binary treatment, binary outcome and no covariate. By adaptive design, we mean in this setting a clinical trial design that allows the investigator to dynamically modify its course through data-driven adjustment of the randomization probability based on data accrued so far, without negatively impacting on the statistical integrity of the trial. By adaptive group sequential design, we refer to the fact that group sequential testing methods can be equally well applied on top of adaptive designs. Prior to collection …

Targeted Maximum Likelihood Based Causal Inference, Mark J. Van Der Laan

U.C. Berkeley Division of Biostatistics Working Paper Series

Given causal graph assumptions, intervention-specific counterfactual distributions of the data can be defined by the so called G-computation formula, which is obtained by carrying out these interventions on the likelihood of the data factorized according to the causal graph. The obtained G-computation formula represents the counterfactual distribution the data would have had if this intervention would have been enforced on the system generating the data. A causal effect of interest can now be defined as some difference between these counterfactual distributions indexed by different interventions. For example, the interventions can represent static treatment regimens or individualized treatment rules that assign …

Bio-Creep In Non-Inferiority Clinical Trials, Siobhan P. Everson-Stewart, Scott S. Emerson

UW Biostatistics Working Paper Series

After a non-inferiority clinical trial, a new therapy may be accepted as effective, even if its treatment effect is slightly smaller than the current standard. It is therefore possible that, after a series of trials where the new therapy is slightly worse than the preceding drugs, an ineffective or harmful therapy might be incorrectly declared efficacious; this is known as “bio-creep.” Several factors may influence the rate at which bio-creep occurs, including the distribution of the effects of the new agents being tested and how that changes over time, the choice of active comparator, the method used to model the …

Estimates Of Information Growth In Longitudinal Clinical Trials, Abigail Shoben, Kyle Rudser, Scott S. Emerson

UW Biostatistics Working Paper Series

In group sequential clinical trials, it is necessary to estimate the amount of information present at interim analysis times relative to the amount of information that would be present at the final analysis. If only one measurement is made per individual, this is often the ratio of sample sizes available at the interim and final analyses. However, as discussed by Wu and Lan (1992), when the statistic of interest is a change over time, as with longitudinal data, such an approach overstates the information. In this paper, we discuss other problems that can result in overestimating the information, such as …

Effects Of Socioeconomic Status On Brain Development, And How Cognitive Neuroscience May Contribute To Levelling The Playing Field, Rajeev Raizada, Mark M. Kishiyama

Dartmouth Scholarship

The study of socioeconomic status (SES) and the brain finds itself in a circumstance unusual for Cognitive Neuroscience: large numbers of questions with both practical and scientific importance exist, but they are currently under-researched and ripe for investigation. This review aims to highlight these questions, to outline their potential significance, and to suggest routes by which they might be approached. Although remarkably few neural studies have been carried out so far, there exists a large literature of previous behavioural work. This behavioural research provides an invaluable guide for future neuroimaging work, but also poses an important challenge for it: how …

Research Poster: Climate Prediction Downscaling Of Temperature And Precipitation In The Great Basin Region, Ramesh Vellore, Benjamin J. Hatchett, Darko Koracin

2010 Annual Nevada NSF EPSCoR Climate Change Conference

Research poster

Research Poster: Hydrological Impacts Of Climate Change On Colorado Basin, Peng Jiang, Zhongbo Yu

2010 Annual Nevada NSF EPSCoR Climate Change Conference

Research poster

Research Poster: An Overview Of Progress In Nsf Epscor Project Entitled, “Reducing Cloud Uncertainties In Climate Models”, Subhashree Mishra, David L. Mitchell, W. Patrick Arnott

2010 Annual Nevada NSF EPSCoR Climate Change Conference

Research poster

Applied Statistics: Experience & Cerification In Quality Assurance, Huey D. Dodson

Statistics

The composition of my senior project can be broken down into two parts. The first part of my project, without which the second could not be pursued, involved a 13 week internship at a produce processing facility where I took part in several projects varying in scope and type. The second part was to acquire certification as a Quality Process Analyst from the American Society for Quality.

This document is structured to represent the dichotomous nature of my project; the first section is dedicated to my internship experience, and the second dedicated to the certification examination preparation and completion.

Integer Functions On The Cycle Space And Edges Of A Graph, Dan Slilaty

Mathematics and Statistics Faculty Publications

A directed graph has a natural Z-module homomorphism from the underlying graph’s cycle space to Z where the image of an oriented cycle is the number of forward edges minus the number of backward edges. Such a homomorphism preserves the parity of the length of a cycle and the image of a cycle is bounded by the length of that cycle. Pretzel and Youngs (SIAM J. Discrete Math. 3(4):544–553, 1990) showed that any Z-module homomorphism of a graph’s cycle space to Z that satisfies these two properties for all cycles must be such a map induced from an edge direction …

The Location Decisions Of Foreign Investors In China: Untangling The Effect Of Wages Using A Control Function Approach, Xuepeng Liu, Mary E. Lovely, Jan Ondrich

Faculty Articles

There is almost no support for the proposition that capital is attracted to low wages from firm-level studies. We examine the location choices of 2,884 firms investing in China between 1993 and 1996 to offer two main contributions. First, we find that the location of labor-intensive activities is highly elastic to provincial wage differences. Generally, investors' wage sensitivity declines as the skill intensity of the industry increases. Second, we find that unobserved location-specific attributes exert a downward bias on estimated wage sensitivity. Using a control function approach, we estimate a downward bias of 50% to 90% in wage coefficients estimated …

Electoral Voting And Population Distribution In The United States, Paul Kvam

Department of Math & Statistics Faculty Publications

In the United States, the electoral system for determining the president is controversial and sometimes confusing to voters keeping track of election outcomes. Instead of directly counting votes to decide the winner of a presidential election, individual states send a representative number of electors to the Electoral College, and they are trusted to cast their collective vote for the candidate who won the popular vote in their state.

Under the current rules, the value of a vote differs from state to state. A large state such as California has an immense effect on the national election, but, compared to a …

Culturally-Adapted And Audio-Technology Assisted Hiv/Aids Awareness And Education Program In Rural Nigeria: A Cohort Study, Ighovwerha Ofotokun, Jose Nilo G. Binongo, Eli S. Rosenberg, Michael Kane, Rick Ifland, Jeffrey L. Lennox, Kirk A. Easley

Faculty Articles

Background: HIV-awareness programs tailored toward the needs of rural communities are needed. We sought to quantify change in HIV knowledge in three rural Nigerian villages following an integrated culturally adapted and technology assisted educational intervention.

Methods: A prospective 14-week cohort study was designed to compare short-term changes in HIV knowledge between seminar-based education program and a novel program, which capitalized on the rural culture of small-group oral learning and was delivered by portable digital-audio technology.

Results: Participants were mostly Moslem (99%), male (53.5%), with no formal education (55%). Baseline HIV knowledge was low (< 80% correct answers for 9 of the 10 questions). Knowledge gain was higher (p < 0.0001 for 8 of 10 questions) in the integrated culturally adapted and technology-facilitated (n = 511) compared with the seminar-based (n = 474) program.

Conclusions: Baseline HIV-awareness was low. Culturally …

The Effects Of Airbags And Seatbelts On Occupant Injury In Longitudinal Barrier Crashes, Doug Gabauer, Hampton C. Gabler

Faculty Journal Articles

The Module Isomorphism Problem Reconsidered

Gamma-Ray Spectroscopy: Meteorite Samples And The Search For 98tc, Kristopher L. Merolla

Physics

The focus of this project is low-count-level gamma-ray spectroscopy on meteorite samples in search of a particular isotope of Technetium (98Tc), which according to stellar theory, should be present in the universe. The spectral lines for 99Tc have, however, been observed in S-, M-, and N- type stars, which makes finding 98Tc created naturally a possibility, and thus a search can be justified.

Robustness Of Approaches To Roc Curve Modeling Under Misspecification Of The Underlying Probability Model, Sean Devlin, Elizabeth Thomas, Scott S. Emerson

UW Biostatistics Working Paper Series

The receiver operating characteristic (ROC) curve is a tool of particular use in disease status classification with a continuous medical test (marker). A variety of statistical regression models have been proposed for the comparison of ROC curves for different markers across covariate groups. A full parametric modeling of the marker distribution has been generally found to be overly reliant on the strong parametric assumptions. Pepe (2003) has instead developed parametric models for the ROC curve that induce a semi-parametric model for the marker distributions. The estimating equations proposed for use in these ROC-GLM models may differ from commonly used estimating …

Simple, Efficient Estimators Of Treatment Effects In Randomized Trials Using Generalized Linear Models To Leverage Baseline Variables, Michael Rosenblum, Mark J. Van Der Laan

U.C. Berkeley Division of Biostatistics Working Paper Series

Models, such as logistic regression and Poisson regression models, are often used to estimate treatment effects in randomized trials. These models leverage information in variables collected before randomization, in order to obtain more precise estimates of treatment effects. However, there is the danger that model misspecification will lead to bias. We show that certain easy to compute, model-based estimators are asymptotically unbiased even when the working model used is arbitrarily misspecified. Furthermore, these estimators are locally efficient. As a special case of our main result, we consider a simple Poisson working model containing only main terms; in this case, we …

Targeted Maximum Likelihood Estimation Of The Parameter Of A Marginal Structural Model, Michael Rosenblum, Mark J. Van Der Laan

U.C. Berkeley Division of Biostatistics Working Paper Series

Targeted maximum likelihood estimation is a versatile tool for estimating parameters in semiparametric and nonparametric models. We work through an example applying targeted maximum likelihood methodology to estimate the parameter of a marginal structural model. In the case we consider, we show how this can be easily done by clever use of standard statistical software. We point out differences between targeted maximum likelihood estimation and other approaches (including estimating function based methods). The application we consider is to estimate the effect of adherence to antiretroviral medications on virologic failure in HIV positive individuals.

Quantification Of Artistic Style Through Sparse Coding Analysis In The Drawings Of Pieter Bruegel The Elder, James M. Hughes, Daniel J. Graham, Daniel N. Rockmore

Dartmouth Scholarship

Recently, statistical techniques have been used to assist art historians in the analysis of works of art. We present a novel technique for the quantification of artistic style that utilizes a sparse coding model. Originally developed in vision research, sparse coding models can be trained to represent any image space by maximizing the kurtosis of a representation of an arbitrarily selected image from that space. We apply such an analysis to successfully distinguish a set of authentic drawings by Pieter Bruegel the Elder from another set of well-known Bruegel imitations. We show that our approach, which involves a direct comparison …