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Parametric Estimation In Competing Risks And Multi-State Models, Yushun Lin 2011 University of Kentucky

Parametric Estimation In Competing Risks And Multi-State Models, Yushun Lin

Theses and Dissertations--Statistics

The typical research of Alzheimer's disease includes a series of cognitive states. Multi-state models are often used to describe the history of disease evolvement. Competing risks models are a sub-category of multi-state models with one starting state and several absorbing states.

Analyses for competing risks data in medical papers frequently assume independent risks and evaluate covariate effects on these events by modeling distinct proportional hazards regression models for each event. Jeong and Fine (2007) proposed a parametric proportional sub-distribution hazard (SH) model for cumulative incidence functions (CIF) without assumptions about the dependence among the risks. We modified their model to …


Stochastic Dynamics Of Gene Transcription, Yan Xie 2011 University of Kentucky

Stochastic Dynamics Of Gene Transcription, Yan Xie

Theses and Dissertations--Statistics

Gene transcription in individual living cells is inevitably a stochastic and dynamic process. Little is known about how cells and organisms learn to balance the fidelity of transcriptional control and the stochasticity of transcription dynamics. In an effort to elucidate the contribution of environmental signals to this intricate balance, a Three State Model was recently proposed, and the transcription system was assumed to transit among three different functional states randomly.

In this work, we employ this model to demonstrate how the stochastic dynamics of gene transcription can be characterized by the three transition parameters. We compute the probability distribution of …


Fully Nonlinear Boundary Value Problems With Impulse, Paul Eloe, Muhammad Usman 2011 University of Dayton

Fully Nonlinear Boundary Value Problems With Impulse, Paul Eloe, Muhammad Usman

Mathematics Faculty Publications

An impulsive boundary value problem with nonlinear boundary conditions for a second order ordinary differential equation is studied. In particular, sufficient conditions are provided so that a compression- expansion cone theoretic fixed point theorem can be applied to imply the existence of positive solutions. The nonlinear forcing term is assumed to satisfy usual sublinear or superlinear growth as t → ∞ or t → 0 +. The nonlinear impulse terms and the nonlinear boundary terms are assumed to satisfy the analogous asymptotic behavior.


Prospective Teachers' Use Of Representations In Solving Statistical Tasks With Dynamic Statistical Software, Hollylynne Lee, Shannon O. Driskell, Suzanne R. Harper, Keith R. Leatham, Gladis Kersaint, Robin L. Angotti 2011 North Carolina State University at Raleigh

Prospective Teachers' Use Of Representations In Solving Statistical Tasks With Dynamic Statistical Software, Hollylynne Lee, Shannon O. Driskell, Suzanne R. Harper, Keith R. Leatham, Gladis Kersaint, Robin L. Angotti

Mathematics Faculty Publications

This study examined a random stratified sample (n=62) of prospective teachers' work across eight institutions on three tasks that utilized dynamic statistical software. Our work was guided by considering how teachers may utilize their statistical knowledge and technological statistical knowledge to engage in cycles of investigation. Although teachers did not tend to take full advantage of dynamic linking capabilities, they utilized a large variety of graphical representations and often added statistical measures or other augmentations to graphs as part of their analysis.


Algorithms For Area Preserving Flows, Catherine Kublik, Selim Esedoglu, Jeffrey A. Fessler 2011 University of Dayton

Algorithms For Area Preserving Flows, Catherine Kublik, Selim Esedoglu, Jeffrey A. Fessler

Mathematics Faculty Publications

We propose efficient and accurate algorithms for computing certain area preserving geometric motions of curves in the plane, such as area preserving motion by curvature. These schemes are based on a new class of diffusion generated motion algorithms using signed distance functions. In particular, they alternate two very simple and fast operations, namely convolution with the Gaussian kernel and construction of the distance function, to generate the desired geometric flow in an unconditionally stable manner. We present applications of these area preserving flows to large scale simulations of coarsening.


How Other Drivers’ Vehicle Characteristics Influence Your Driving Speed, Russell Brockett 2011 Claremont McKenna College

How Other Drivers’ Vehicle Characteristics Influence Your Driving Speed, Russell Brockett

CMC Senior Theses

An analysis of the effect of passing vehicles’ characteristics and their impact on other drivers’ velocities was investigated.  Three experimental studies were proposed and likely outcomes were discussed.  Experiment 1 focused on the effect of passing vehicle type (SUV, sedan or truck) on driver speed.  Drivers were hypothesized as going faster when the same vehicle type as they were driving passed them versus when no vehicle or a different vehicle passed them.  Experiment 2 focused on the effect of passing SUV age on driver’s speed.  Evidence suggests passing older SUVs will increase the driver’s speed more than new SUVs.  Experiment …


Applying Localized Realized Volatility Modeling To Futures Indices, Luella Fu 2011 Claremont McKenna College

Applying Localized Realized Volatility Modeling To Futures Indices, Luella Fu

CMC Senior Theses

This thesis extends the application of the localized realized volatility model created by Ying Chen, Wolfgang Karl Härdle, and Uta Pigorsch to other futures markets, particularly the CAC 40 and the NI 225. The research attempted to replicate results though ultimately, those results were invalidated by procedural difficulties.


Ohio's Use Of Geographic Information Systems To Demonstrate Public Participation In The Redistricting Process, Mark Salling 2011 Cleveland State University

Ohio's Use Of Geographic Information Systems To Demonstrate Public Participation In The Redistricting Process, Mark Salling

All Maxine Goodman Levin School of Urban Affairs Publications

No abstract provided.


Gis Will Affect The Political Landscape For The Next Decade And Beyond, Mark Salling 2011 Cleveland State University

Gis Will Affect The Political Landscape For The Next Decade And Beyond, Mark Salling

All Maxine Goodman Levin School of Urban Affairs Publications

No abstract provided.


Public Participation Geographic Information Systems For Redistricting A Case Study In Ohio, Mark Salling 2011 Cleveland State University

Public Participation Geographic Information Systems For Redistricting A Case Study In Ohio, Mark Salling

All Maxine Goodman Levin School of Urban Affairs Publications

Public Participation Geographic Information Systems for Redistricting A Case Study in Ohio, Journal of the Urban and Regional Information Systems Association, Vol. 23, Number 1, forthcoming.


Summative Confidence, Paul Cristian Gugiu 2011 Western Michigan University

Summative Confidence, Paul Cristian Gugiu

Dissertations

Often the singular goal of an evaluation is to render a summative conclusion of merit, worth or feasibility that is based on multiple streams of multidimensional data. Exacerbating this difficulty, conducting evaluations in real-world settings often necessitates implementation of less than ideal study designs. This reality gets further complicated by the standard method for estimating the precision of results via the confidence interval (CI). Traditional CIs offer a limited approach for understanding the precision of a summative conclusion. This dissertation develops and presents a unified approach for the construction of a CI for a summative conclusion (SC).

This study derived …


Robust Adaptive Scheme For Linear Mixed Models, Gabriel Asare Okyere 2011 Western Michigan University

Robust Adaptive Scheme For Linear Mixed Models, Gabriel Asare Okyere

Dissertations

If the underlying distribution of a statistical model is known then a procedure which maximizes power and efficiency can be selected. For example, if the distribution of errors is known to be normal in a linear model then inference based on least squares maximizes power and efficiency. More generally, if this distribution is known then a ranked based inference based on the appropriate rank score function has maximum efficiency. In practice, though, this distribution is not known. Adaptive schemes are procedures which hopefully select appropriate methods to optimize the analysis.

Hogg (1974) presented an adaptive rank-based scheme for testing in …


Robust Nonparametric Methods For Regression To The Mean Model, Therawat Wisadrattanapong 2011 Western Michigan University

Robust Nonparametric Methods For Regression To The Mean Model, Therawat Wisadrattanapong

Dissertations

Regression to the mean is a statistical phenomenon that often confounds treatment effects in experiments. Consider an experiment involving a treatment, in which a response is measured (baseline) on a subject then a treatment is applied and a second measurement is taken. Then under many bivariate models for the pair of responses (including the bivariate normal), the predicted response of the second measurement will regress to the mean. In experiments where the second response is only taken for a select sample, say above a cutoff value, then this regression to the mean effect may mistakenly be thought of as a …


The Doubly Inflated Poisson And Related Regression Models, Manasi Sheth-Chandra 2011 Old Dominion University

The Doubly Inflated Poisson And Related Regression Models, Manasi Sheth-Chandra

Mathematics & Statistics Theses & Dissertations

Most real life count data consists of some values that are more frequent than allowed by the common parametric families of distributions. For data consisting of only excess zeros, in a seminal paper Lambert (1992) introduced Zero-Inflated Poisson (ZIP) model, which is a mixture model that accounts for the inflated zeros. In this thesis, two Doubly Inflated Poisson (DIP) probability models, DIP (p, λ) and DIP ( p1, p2, λ), are discussed for situations where there is another inflated value k > 0 besides the inflated zeros. The distributional properties such as identifiability, moments, and conditional probabilities …


Modeling And Analysis Of Repeated Ordinal Data Using Copula Based Likelihoods And Estimating Equation Methods, Raghavendra Rao Kurada 2011 Old Dominion University

Modeling And Analysis Of Repeated Ordinal Data Using Copula Based Likelihoods And Estimating Equation Methods, Raghavendra Rao Kurada

Mathematics & Statistics Theses & Dissertations

Repeated or longitudinal ordinal data occur in many fields such as biology, epidemiology, and finance. These data normally are analyzed using both likelihood and non-likelihood methods. The first part of this dissertation discusses the multivariate ordered probit model which is a likelihood method based on latent variables. We show that this latent variable model belong to a very general class of Copula models. We use the copula representation for the multivariate ordered probit model to obtain maximum likelihood estimates of the parameters. We apply the methodology in the analysis of real life data examples.

Though likelihood methods are preferable, there …


A Characterization Of Connected (1,2)-Domination Graphs Of Tournaments, Kim A. S. Factor, Larry J. Langley 2011 Marquette University

A Characterization Of Connected (1,2)-Domination Graphs Of Tournaments, Kim A. S. Factor, Larry J. Langley

Mathematics, Statistics and Computer Science Faculty Research and Publications

Recently. Hedetniemi et aI. introduced (1,2)-domination in graphs, and the authors extended that concept to (1, 2)-domination graphs of digraphs. Given vertices x and y in a digraph D, x and y form a (1,2)-dominating pair if and only if for every other vertex z in D, z is one step away from x or y and at most two steps away from the other. The (1,2)-dominating graph of D, dom1,2 (D), is defined to be the graph G = (V, E ) , where V (G) = V (D), and xy is …


Bayesian Item Response Theory: Statistical Inference And Power Analysis, Jason W. Bodnar 2011 Western Michigan University

Bayesian Item Response Theory: Statistical Inference And Power Analysis, Jason W. Bodnar

Dissertations

The regulatory pharmaceutical approval process is flawed in that industry clinical trials (ICTs) are always powered for efficacy and rarely powered for safety. The key safety parameter is the adverse event (AE). This practice may result in efficacious products with confounded safety. An ICT’s ability to be powered for detecting AE trends may improve patient safety. Therefore, this dissertation’s purpose was to determine if power analysis resulted in feasible sample sizes for substantiating AE hypotheses. AEs were modeled with three Bayesian 2PL IRT models. The unidimensional latent trait, transfusion-related AE, was modeled as a patient predisposition for experiencing an AE. …


Death By Boredom: The Role Of Visual Processing Theory In Written Evaluation Communication, Stephanie D. H. Evergreen 2011 Western Michigan University

Death By Boredom: The Role Of Visual Processing Theory In Written Evaluation Communication, Stephanie D. H. Evergreen

Dissertations

Evaluation reporting is an educational act and, as such, should be communicated using principles that support cognition. This study drew upon visual processing theory and theory-based graphic design principles to develop the Evaluation Report Layout Checklist intended to guide report development and support cognition in the readers of evaluation reports. It was then reviewed by an expert panel and applied by a group of raters to a set of evaluation reports obtained from the Informal Science Education evaluation website with maximum variability sampling. Results showed fairly high exact percent agreement and strong to very strong correlation with the author’s ratings. …


Longitudinal Investigation Of The Curricular Effect: An Analysis Of Student Learning Outcomes From The Liecal Project In The United States, Jinfa Cai, Ning Wang, John Moyer, Chuang Wang, Bikai Nie 2011 University of Delaware

Longitudinal Investigation Of The Curricular Effect: An Analysis Of Student Learning Outcomes From The Liecal Project In The United States, Jinfa Cai, Ning Wang, John Moyer, Chuang Wang, Bikai Nie

Mathematics, Statistics and Computer Science Faculty Research and Publications

In this article, we present the results from a longitudinal examination of the impact of a Standards-based or reform mathematics curriculum (called CMP) and traditional mathematics curricula (called non-CMP) on students’ learning of algebra using various outcome measures. Findings include the following: (1) students did not sacrifice basic mathematical skills if they are taught using a Standards-based or reform mathematics curriculum like CMP; (2) African American students experienced greater gain in symbol manipulation when they used a traditional curriculum; (3) the use of either the CMP or a non-CMP curriculum improved the mathematics achievement of all students, including …


Statistical Analysis And Mechanistic Modeling Of Water Quality: Hillsborough Bay, Florida, Keith Hackett 2011 University of South Florida

Statistical Analysis And Mechanistic Modeling Of Water Quality: Hillsborough Bay, Florida, Keith Hackett

USF Tampa Graduate Theses and Dissertations

Nutrient pollution has been identified as a significant threat to U.S. coastal and estuarine water quality. Though coastal and estuarine waters need nutrients to maintain a healthy, productive ecosystem, excess nutrients can lead to eutrophication. There are significant potential negative consequences associated with eutrophication, including loss of habitat, loss of economic activity, and direct threats to human health. Hillsborough Bay experienced eutrophication in the 1960s and 1970s due to a rapidly growing population and associated increases in nutrient pollution. These eutrophic conditions led to more frequent phytoplankton and macroalgae blooms and declines in seagrasses. To address these problems, a series …


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