Statistics and Probability Commons^™

Pre- And Post-Diagnosis Physical Activity, Television Viewing, And Mortality Among Hematologic Cancer Survivors., Daniela Schmid, Gundula Behrens, Hannah Arem, Christina Hart, Wolfgang Herr, Carmen Jochem, Charles E Matthews, Michael F Leitzmann

Epidemiology Faculty Publications

PURPOSE: The associations of physical activity and television (TV) viewing with mortality risk among individuals with hematologic malignancies remain unclear.

METHODS: We examined the relations of physical activity and TV viewing time before and after diagnosis with mortality among 5182 U.S. adults aged 50-71 years from the NIH-AARP Diet and Health Study cohort who survived a first primary hematologic cancer between 1995-1996 and 2011.

RESULTS: For the pre- and post-diagnosis analyses, we confirmed 2606 and 613 deaths respectively. In multivariable-adjusted Cox proportional hazard regression models, comparing high (≥4 hrs/wk) versus low (/wk) activity levels, pre-diagnosis physical activity was associated with …

Impact Of Chronic Sexual Abuse And Depression On Inflammation And Wound Healing In The Female Reproductive Tract Of Hiv-Uninfected And Hiv-Infected Women., Mimi Ghosh, Jason Daniels, Maria Pyra, Monika Juzumaite, Mariel Jais, Kerry Murphy, Tonya N Taylor, Seble Kassaye, Lorie Benning, Mardge Cohen, Kathleen Weber

Epidemiology Faculty Publications

Sexual violence is associated with increased risk of HIV acquisition/transmission in women. Forced sex can result in physical trauma to the reproductive tract as well as severe psychological distress. However, immuno-biological mechanisms linking sexual violence and HIV susceptibility are incompletely understood. Using the Women's Interagency HIV Study repository, a total of 77 women were selected to form 4 groups, stratified by HIV serostatus, in the following categories: 1) no sexual abuse history and low depressive symptom score (below clinically significant cut-off, scores

Piloting Very Early Infant Diagnosis Of Hiv In Lesotho: Acceptability And Feasibility Among Mothers, Health Workers And Laboratory Personnel., Michelle M Gill, Lynne M Mofenson, Mamakhetha Phalatse, Vincent Tukei, Laura Guay, Matsepeli Nchephe

Epidemiology Faculty Publications

INTRODUCTION: Mortality associated with in-utero HIV infection rises rapidly within weeks after birth. Very early infant diagnosis of HIV (VEID)-testing within 2 weeks of birth-followed by immediate initiation of antiretroviral therapy has potential to avert mortality associated with in-utero transmission. However, our understanding of acceptability and feasibility of VEID is limited.

METHODS: VEID was piloted in an observational prospective cohort of HIV-positive pregnant women and their infants in 13 Lesotho health facilities. Between March-July 2016, semi-structured interviews were conducted with HIV-positive women attending 6-week or 14-week postnatal visits and health workers (HWs) in 8 study facilities in 3 districts as …

Sexually Transmitted Infections Among Hiv-Infected Individuals In The District Of Columbia And Estimated Hiv Transmission Risk: Data From The Dc Cohort, Jose Lucar, Rachel Hart, Nabil Rayeed, Arpi Terzian, Amy Weintrob, Amanda D. Castel, Debra A. Benator, Dc Cohort Executive Committee

Epidemiology Faculty Publications

Background

Washington, DC, has one of the highest rates of HIV infection in the United States. Sexual intercourse is the leading mode of HIV transmission, and sexually transmitted infections (STIs) are a risk factor for HIV acquisition and transmission.

Methods

We evaluated the incidence and demographic factors associated with chlamydia, gonorrhea, and syphilis among HIV-infected persons enrolled at 13 DC Cohort sites from 2011 to 2015. Using Poisson regression, we assessed covariates of risk for incident STIs. We also examined HIV viral loads (VLs) at the time of STI diagnosis as a proxy for HIV transmission risk.

Results

Six point …

A Proposed Taxonomy For The Systems Statistical Engineering Body Of Knowledge, Teddy Steven Cotter

Engineering Management & Systems Engineering Faculty Publications

In the ASEM-IAC 2012, Cotter (2012) identified the gaps in knowledge that statistical engineering needs to address, explored additional gaps in knowledge not addressed in the prior works, and set forth a working definition of and body of knowledge for statistical engineering. In the ASEM-IAC 2015, Cotter (2015) proposed a systemic causal Bayesian hierarchical model that addressed the knowledge gap needed to integrate deterministic mathematical engineering causal models within a stochastic framework. Missing, however, is the framework for specifying the hierarchical qualitative systems structures necessary and sufficient for specifying systemic causal Bayesian hierarchical models. In the ASEM-IAC 2016, Cotter (2016) …

Synthesis And Large-Scale Textual Corpora: A Nested Topic Model Of Britain's Debates Over Landed Property In The Nineteenth Century, Jo Guldi, Benjamin Williams

History Faculty Publications

Scholars need tools that will allow them to generalize about the fit of themes, events, and rhetorical styles represented in a body of texts. In this article, we introduce the concept of “nested topics,” an approach to topic modeling large-scale textual corpora that highlights implicit ontologies and relationships within the texts themselves. This tool exploits the fact that topic modeling can be used to generalize about topics on an aggregate level as well as a fine-grained level, an approach that has the consequences of revealing overarching themes that appear across all texts as well as more idosyncratic events and rehtorical …

Spatiotemporal Variations In Coexisting Multiple Causes Of Death And The Associated Factors, Emmanuel Oluwatobi Salawu

Walden Dissertations and Doctoral Studies

The study and practice of epidemiology and public health benefit from the use of mortality statistics, such as mortality rates, which are frequently used as key health indicators. Furthermore, multiple causes of death (MCOD) data offer important information that could not possibly be gathered from other mortality data. This study aimed to describe the interrelationships between various causes of death in the United States in order to improve the understanding of the coexistence of MCOD and thereby improve public health and enhance longevity. The social support theory was used as a framework, and multivariate linear regression analyses were conducted to …

Aggressive Diuresis And Severity-Adjusted Length Of Hospital Stay In Acute Congestive Heart Failure Patients, Muhammad U. Butt

Theses and Dissertations--Clinical Research Design

To see if aggressive diuresis in first twenty four hours is associated with a comparable number of total days in the hospital as compared to non-aggressive diuresis. In this retrospective cohort study, we compared the length of hospital stay of consecutive patients admitted in one year based on their diuresis during the first twenty-four hours of hospitalization: aggressive diuresis (group 1) i.e. > 2400mL versus non-aggressive diuresis (group 2) i.e. ≤ 2400mL urine output. Patients were excluded if in cardiogenic shock, had creatinine level above 3 mg/dL on admission, or on dialysis. A total of 194 patients were enrolled (29 in …

Mixture Models With Grouping Structure: Retail Analytics Applications, Haidar Almohri

Wayne State University Dissertations

Growing competitiveness and increasing availability of data is generating tremendous interest in data-driven analytics across industries. In the retail sector, stores need targeted guidance to improve both the efficiency and effectiveness of individual stores based on their specific location, demographics, and environment. We propose an effective data-driven framework for internal benchmarking that can lead to targeted guidance for individual stores. In particular, we propose an objective method for segmenting stores using a model-based clustering technique that accounts for similarity in store performance dynamics. It relies on effective Finite Mixture of Regression (FMR) techniques for carrying out the model-based clustering with …

Iterative Matrix Factorization Method For Social Media Data Location Prediction, Natchanon Suaysom

HMC Senior Theses

Since some of the location of where the users posted their tweets collected by social media company have varied accuracy, and some are missing. We want to use those tweets with highest accuracy to help fill in the data of those tweets with incomplete information. To test our algorithm, we used the sets of social media data from a city, we separated them into training sets, where we know all the information, and the testing sets, where we intentionally pretend to not know the location. One prediction method that was used in (Dukler, Han and Wang, 2016) requires appending one-hot …

Dimension Reduction For Classification With Many Covariates And Pathway Activity Level Estimation, Seungchul Baek

Theses and Dissertations

The development of science and technology has enabled the use of more covariates. As a result, it has become more difficult to identify dependencies among many covariates. Dimension reduction provides an efficient way to handle this issue by summarizing the effect of covariates via a few linear combinations of covariates. In this dissertation, two methodologies for real-life problems are provided by using dimension reduction equipped with semiparametric theory. The use of semiparametrics allows maximal flexibility of the model by letting some features of the model completely unspecified, while we still enjoy the interpretability of the model through estimating the parameters …

Borrowing Capacity, Financial Instability, And Contagion: Case Study Of The U.S. Subprime Mortgage Crisis, Youngna Choi

Department of Applied Mathematics and Statistics Faculty Scholarship and Creative Works

We use the case of the 2007 United States subprime mortgage crisis to investigate the impact of borrowing capacity limitations on financial instability and contagion. We divide an economy into agents that interact via flow of funds and express the financial instability level of each agent as a function of time derivatives of its wealth, cash inflows, and borrowing capacity. We show that among these factors, the borrowing capacity, which is determined by other economic constraints, has the largest impact on financial instability. It is suggested that borrowing capacity limitations could even cause contagion through feedback loop formed by flow …

The Impact Of Truncating Data On The Predictive Ability For Single-Step Genomic Best Linear Unbiased Prediction, Jeremy T. Howard, Thomas A. Rathje, Caitlyn E. Bruns, Danielle F. Wilson-Wells, Stephen D. Kachman, Matthew L. Spangler

Department of Animal Science: Faculty Publications

Simulated and swine industry data sets were utilized to assess the impact of removing older data on the predictive ability of selection candidate estimated breeding values (EBV) when using single-step genomic best linear unbiased prediction (ssGBLUP). Simulated data included thirty replicates designed to mimic the structure of swine data sets. For the simulated data, varying amounts of data were truncated based on the number of ancestral generations back from the selection candidates. The swine data sets consisted of phenotypic and genotypic records for three traits across two breeds on animals born from 2003 to 2017. Phenotypes and genotypes were iteratively …

Effect Of Socioeconomic And Demographic Factors On Kentucky Crashes, Aaron Berry Cambron

Theses and Dissertations--Civil Engineering

The goal of this research was to examine the potential predictive ability of socioeconomic and demographic data for drivers on Kentucky crash occurrence. Identifying unique background characteristics of at-fault drivers that contribute to crash rates and crash severity may lead to improved and more specific interventions to reduce the negative impacts of motor vehicle crashes. The driver-residence zip code was used as a spatial unit to connect five years of Kentucky crash data with socioeconomic factors from the U.S. Census, such as income, employment, education, age, and others, along with terrain and vehicle age. At-fault driver crash counts, normalized over …

Psychometric Properties Of A Working Memory Span Task, Juan M. Alzate Vanegas

Honors Undergraduate Theses

The intent of this thesis is to examine the psychometric properties of a complex span task (CST) developed to measure working memory capacity (WMC) using measurements obtained from a sample of 68 undergraduate students at the University of Central Florida. The Grocery List Task (GLT) promises several design improvements over traditional CSTs in a prior study about individual differences in WMC and distraction effects on driving performance, and it offers potential benefits for studying WMC as well as the serial-position effect. Currently, the working memory system is composed of domain-general memorial storage processes and information-processing, which involves the use of …

Examining The Issue Of Compliance With Personal Protective Equipment Among Wastewater Workers Across The Southeast Region Of The United States, Tamara L. Wright

College of Graduate Studies: Theses & Dissertations

Wastewater workers are exposed to different occupational hazards such as chemicals, gases, viruses, and bacteria. Personal Protective Equipment (PPE) is a significant factor that can reduce or increase the probability of an accident from hazardous exposures to chemicals and microbial contaminants. The purpose of this study was to identify wastewater worker’s beliefs and practices on wearing PPE and protections offered by PPE through the integration of the Health Belief Model (HBM). Participants were workers in the wastewater industry, which included wastewater operators, laboratory analysts, maintenance workers, wastewater collection workers, equipment operators, managers, and supervisors (n=272). The instrument was a self-administered …

Decoupled, Linear, And Energy Stable Finite Element Method For The Cahn-Hilliard-Navier-Stokes-Darcy Phase Field Model, Yali Gao, Xiaoming He, Liquan Mei, Xiaofeng Yang

Mathematics and Statistics Faculty Research & Creative Works

In this paper, we consider the numerical approximation for a phase field model of the coupled two-phase free flow and two-phase porous media flow. This model consists of Cahn—Hilliard—Navier—Stokes equations in the free flow region and Cahn—Hilliard—Darcy equations in the porous media region that are coupled by seven interface conditions. The coupled system is decoupled based on the interface conditions and the solution values on the interface from the previous time step. A fully discretized scheme with finite elements for the spatial discretization is developed to solve the decoupled system. In order to deal with the difficulties arising from the …

The Impact Of Data Sovereignty On American Indian Self-Determination: A Framework Proof Of Concept Using Data Science, Joseph Carver Robertson

Electronic Theses and Dissertations

The Data Sovereignty Initiative is a collection of ideas that was designed to create SMART solutions for tribal communities. This concept was to develop a horizontal governance framework to create a strategic act of sovereignty using data science. The core concept of this idea was to present data sovereignty as a way for tribal communities to take ownership of data in order to affect policy and strategic decisions that are data driven in nature. The case studies in this manuscript were developed around statistical theories of spatial statistics, exploratory data analysis, and machine learning. And although these case studies are …

Location Optimization Of A Coal Power Plant To Balance Coal Supply And Electric Transmission Costs Against Plant’S Emission Exposure, Najam Khan

Electronic Theses and Dissertations

This research is focused on developing a location analysis methodology that can minimize the pollutant exposure to the public while ensuring that the combined costs of electric transmission losses and coal logistics are minimized. Coal power plants will provide a critical contribution towards meeting electricity demands for various nations in the foreseeable future. The site selection for a new coal power plant is extremely important from an investment point of view. The operational costs for running a coal power plant can be minimized by a combined emphasis on placing a coal power plant near coal mines as well as customers. …

Mechanism Design, Matching Theory And The Stable Roommates Problem, Yashaswi Mohanty

Honors Theses

This thesis consists of two independent albeit related chapters. The first chapter introduces concepts from mechanism design and matching theory, and discusses potential applications of this theory, particularly in relation to dorm allocations in colleges. The second chapter investigates a subset of the dorm allocation problem, namely that of matching roommates. In particular, the paper looks at the probability of solvability of random instances of the stable roommates game under the condition that preferences are not completely random and exogenous but endogenously determined through a dependence on room choice. These probabilities are estimated using Monte-Carlo simulations and then compared with …