Characterizing The Morphology Of Solvent Annealed Pcbm/P3ht Bilayers Using Gixrd And Raman Spectroscopy,
2014
University of Tennessee - Knoxville
Characterizing The Morphology Of Solvent Annealed Pcbm/P3ht Bilayers Using Gixrd And Raman Spectroscopy, Tyler Evan Mcpherson
Masters Theses
A growing demand for new forms of renewable energy has been at the forefront of scientific research. Organic photovoltaics (OPVs) provide a promising alternative to the expensive inorganic solar cells used today. Poly(3-hexylthiophene) (P3HT) and [6,6]-phenyl C61-butyric acid methyl ester (PCBM) are common donor and acceptor materials used in the active layer of an OPV device. These systems have reached power conversion efficiencies of approximately 12 %. However, little is known about the actual morphology. A better understanding of the morphology would allow researchers to optimize device fabrication to increase the device performance. As-cast devices are limited by the processing …
Synthesis And Functionalization Of Bodipy Dyes For Applications In The Detection Of Colorectal Cancer,
2014
Louisiana State University
Synthesis And Functionalization Of Bodipy Dyes For Applications In The Detection Of Colorectal Cancer, Logan Elise Leblanc
Honors Theses
No abstract provided.
Metal Oxide Nanostructures For Energy Conversion And Storage,
2014
University of Texas-Pan American
Metal Oxide Nanostructures For Energy Conversion And Storage, Xing Sun
Theses and Dissertations - UTB/UTPA
With the depletion of non-renewable resources and the related problems such as environmental pollutions and global warming effect, the society urgently needs more efficient and controllable energy conversion and storage systems. Three-dimensional ZnO nanoforests were prepared and morphology-tunable, which benefits both of energy conversion and storage systems. Willow-like ZnO nanoforests led the highest conversion efficiency of photoelectrochemical water splitting in reported pure ZnO nanostructures. Compared with nanowire arrays, ZnO@MnO2 nanoforests delivered 5 times higher specific capacitances within the same footprint area. V2O5@PPy exhibited higher specific capacitance and better rate stability than pure V2O5 nanofibers. This work lays the foundation for …
Cloning And Characterization Of Ef-Tu And Ef-Ts From Streptococcus Pneumoniae,
2014
University of Texas-Pan American
Cloning And Characterization Of Ef-Tu And Ef-Ts From Streptococcus Pneumoniae, Carlos Eduardo Rivera
Theses and Dissertations - UTB/UTPA
Antibiotic resistance is a prevalent threat to public health around the world, and resistance among strains of Streptococcus pneumoniae is growing rapidly. This increasing resistance elevates the demand for new drug discoveries. This research attempts to develop a means to combat S. pneumoniae by targeting protein synthesis for the discovery of new antibacterial agents. Protein synthesis components, elongation factor Tu (EF-Tu) and elongation factor Ts (EF-Ts) facilitate many steps in the biosynthesis of proteins and are therefore essential proteins involved in protein synthesis. EF-Tu and EF-Ts were cloned, expressed, purified, and enzymatically characterized to help develop a screening system that …
Effects Of Varying The Cure Profiles Of An Epoxy-Amine System,
2014
University of Southern Mississippi
Effects Of Varying The Cure Profiles Of An Epoxy-Amine System, Patrick W. Hollingsworth
Honors Theses
The cure of an epoxy prepolymer with an amine hardener induces stress in thermosetting systems. The extent of residual stresses in the cured epoxy-amine thermosets are dependent on several factors; one of which is the cure profile utilized. The effect of cure profile on cure induced stresses of an epoxy-amine thermoset was examined in the current study. A difunctional epoxide based on diglycidyl ether of bisphenol-A (DGEBA) and a tetrafunctional amine curative were used to conduct this study. Two cure profiles were selected to prepare samples of varying degrees of stress in the cured thermosets. The first was constant heating …
Syntheses And Characterizations Of 4-Cyano-3-Tolylpyrazole And Its Metal Complexes,
2014
East Tennessee State University
Syntheses And Characterizations Of 4-Cyano-3-Tolylpyrazole And Its Metal Complexes, Molly M. Ketron
Undergraduate Honors Theses
Research on substituted polypyrazolylborate ligands could potentially lead to the development of useful compounds in the material sciences such as catalysis and metal ion extraction. A wide variety of substituents can be introduced to the pyrazole rings that modify the properties and reactivity of the complexes. Synthesis of 4-cyano-3-tolylpyrazole followed by the formation of a corresponding thallium(I) complex could allow one to examine the Tl-N bond length. When compared with other related complexes such as TlBpt-Bu, 4CN and TlBpPh, 4CN, the Tl-N bond length in the synthesized complex will help determine the effect of the new …
The Analysis Of The Decomposition Of Hydrogen Peroxide Using A Schiff Base Copper Complex By Cyclic Voltammetry,
2014
East Tennessee State University
The Analysis Of The Decomposition Of Hydrogen Peroxide Using A Schiff Base Copper Complex By Cyclic Voltammetry, Gavin James Rustin Mr.
Undergraduate Honors Theses
Copper(II) complexes of Schiff bases can be used in the catalysis of hydrogen peroxide to create water and oxygen. The mechanism and the kinetics of this disproportionation reaction by a dimeric copper(II) complex [CuSALAD]2 are studied in this experiment, where SALAD refers to a Schiff Base ligand formed from salicyaldehyde and 1S,2S-D(+)-1-phenyl-2-amino-1,3-propanediol. By using cyclic voltammetry, the oxidation-reduction processes of a reaction may be monitored. The [CuSALAD]2 is initially reacted with a base such as imidazole to form the catalytic species, and the ratio of the copper(II) complex to the imidazole was found to be 1:4, consistent with …
Tip-Enhances Raman Spectroscopy, Enabling Spectroscopy At The Nanoscale,
2014
The University of Western Ontario
Tip-Enhances Raman Spectroscopy, Enabling Spectroscopy At The Nanoscale, Nastaran Kazemi Zanjani
Electronic Thesis and Dissertation Repository
The knowledge on the chemical and the structural properties of substances benefits strongly from characterization methods that can provide access to the sample’s nanoscale building blocks. Not only should the sensitivity of these methods approach a high detection limit up to single molecule, but also the accessible spatial resolution must enable chemical imaging of individual nanoscale features of the substances. High resolution imaging is often provided by electron microscopes through methods such as transmission electron microscopy (TEM) and scanning electron microscopy (STM), nevertheless, these methods lack offering chemical information. Surface-enhanced spectroscopy was developed to improve the sensitivity of the chemical …
Nicotine And What Else?: Hplc Elution Optimization For The Analysis Of Alkaloids Found In Electronic Cigarettes,
2014
University of Tennessee at Chattanooga
Nicotine And What Else?: Hplc Elution Optimization For The Analysis Of Alkaloids Found In Electronic Cigarettes, Jessica L. Murray
Honors Theses
Electronic cigarettes, or e-cigarettes, have been scrutinized by the Food and Drug Administration and other public health organizations for issues related to quality control and efficacy. Erratic nicotine delivery and numerous toxic compounds in refill solutions have been reported. The ultimate goal of this research is to add to the growing amount of knowledge regarding e-cigarette ingredient content, safety, and quality. Standards of the tobacco alkaloids nicotine, anabasine, cotinine, and myosmine were prepared and quantified using high performance liquid chromatography (HPLC). Various elution schemes were tested and adjusted for optimal analyte resolution, and a final elution scheme was developed to …
Purple Urine Bag Syndrome: Regulation Of Pyrimidine Enzymes,
2014
University of Tennessee at Chattanooga
Purple Urine Bag Syndrome: Regulation Of Pyrimidine Enzymes, Ashley N. Broadway
Honors Theses
Purple Urine Bag Syndrome, PUBS, is a unique condition that shows an interesting discoloration of the urine from women who have a chronic catheter. This study focused on the regulation of enzyme activities to determine the effects that may create an environment where PUBS is seen in patients with catheters. In this study, the reductive pyrimidine pathway was used to read out the bacteria Pseudomonas aeruginosa ATCC 15692. This microorganism expresses a pathway that synthesizes indoxyl from tryptophan. The bacteria strains were grown using various carbon and nitrogen sources. Concentrations of acetonitrile at 2 mM and 10 mM, concentrations of …
Green's Functions Of Discrete Fractional Calculus Boundary Value Problems And An Application Of Discrete Fractional Calculus To A Pharmacokinetic Model,
2014
Western Kentucky University
Green's Functions Of Discrete Fractional Calculus Boundary Value Problems And An Application Of Discrete Fractional Calculus To A Pharmacokinetic Model, Sutthirut Charoenphon
Masters Theses & Specialist Projects
Fractional calculus has been used as a research tool in the fields of pharmacology, biology, chemistry, and other areas [3]. The main purpose of this thesis is to calculate Green's functions of fractional difference equations, and to model problems in pharmacokinetics. We claim that the discrete fractional calculus yields the best prediction performance compared to the continuous fractional calculus in the application of a one-compartmental model of drug concentration. In Chapter 1, the Gamma function and its properties are discussed to establish a theoretical basis. Additionally, the basics of discrete fractional calculus are discussed using particular examples for further calculations. …
Functionalization And Modification Of Naphthaquinone Analogs As Her2 Kinase Inhibitors,
2014
Western Kentucky University
Functionalization And Modification Of Naphthaquinone Analogs As Her2 Kinase Inhibitors, Divya Jyothi Lella
Masters Theses & Specialist Projects
HER2 overexpression in breast cancer tumors predicts lower overall survival. Because of the aggressive nature of HER2 tumors and the association with metastatic disease, the HER2 receptor holds great promise as a therapeutic target in metastatic breast cancer. We are developing small molecule inhibitors that bind to the ATP binding site of the tyrosine kinase domain in order to inhibit tyrosine auto-phosphorylation. This process controls biological pathways that mediate the cell growth. In normal cells this process is highly controlled. We are targeting the modification of the side chain of the hydroxy methyl group of 2-Hydroxy methyl-5,8-dimethoxy-1,4-naphthaquinone. These compounds should …
New Synthetic Methodologies For Chemo-, Stereo-, And Regioselective 1,4-Conjugate Additions Of Organometallic Reagents To Michael And Extended Michael Substrates And Alkene Halofunctionalization Reactions,
2014
Clemson University
New Synthetic Methodologies For Chemo-, Stereo-, And Regioselective 1,4-Conjugate Additions Of Organometallic Reagents To Michael And Extended Michael Substrates And Alkene Halofunctionalization Reactions, Ramesh Dhakal
All Dissertations
The research discussed in this dissertation is focused on developing new synthetic methodologies for the construction of carbon-carbon and carbon-heteroatom bonds present in several natural products and synthetic intermediates employing organometallic reagents and/or organocatalytic procedure. The presence of rich functionality in the reactive synthons under study provides opportunities for studying a variety of reactions. Effecting a reaction in a regio- and stereoselective fashion is highly attractive as the resulting synthons can be used for the syntheses of larger molecules. We have explored unprecedented variation of Michael Initiated Ring Closure (MIRC) reactions for the syntheses of 1,2,3-trisubstituted cyclopropane derivatives, owing to …
Building Chemistry One Atom At A Time: An Investigation Of The Effects Of Two Curricula In Students' Understanding Of Covalent Bonding And Atomic Size,
2014
Clemson University
Building Chemistry One Atom At A Time: An Investigation Of The Effects Of Two Curricula In Students' Understanding Of Covalent Bonding And Atomic Size, Barbara Bull
All Dissertations
Chemists have to rely on models to aid in the explanation of phenomena they experience. Instruction of atomic theory has been used as the introduction and primary model for many concepts in chemistry. Therefore, it is important for students to have a robust understanding of the different atomic models, their relationships and their limitations. Previous research has shown that students have alternative conceptions concerning their interpretation of atomic models, but there is less exploration into how students apply their understanding of atomic structure to other chemical concepts. Therefore, this research concentrated on the development of three Model Eliciting Activities to …
Expanding The Frontier Of Gold-Catalyzed Cyclizations And Rational Ligand Design.,
2014
University of Louisville
Expanding The Frontier Of Gold-Catalyzed Cyclizations And Rational Ligand Design., Deepika Malhotra
Electronic Theses and Dissertations
The focus of my dissertation work is to study the gold-catalyzed intramolecular and intermolecular cyclizations involving oxonium intermediates towards the application of synthetically interesting frameworks under ambient conditions and developing a rational approach for the effective catalyst design in gold catalysis. We explored the goldcatalyzed oxygen-transfer reactions of 2-alkynyl-1,5-diketones or 2-alkynyl-5-ketoesters to furnish five-membered rings bearing a quaternary carbon tethered to a carbonyl group. The detailed mechanistic investigation on the newly proposed intramolecular [4+2] cycloaddition mechanism was performed by means of isotopic experiments and quantum chemical calculations. The reactivity of alkynylenolate was investigated in the reactions of allenic ketones and …
Synthesis Of N-Heterocycles Through Cyclization-Triggered Tandem Additions To Alkynes And The Study Of Promoters In Ionic Reactions.,
2014
University of Louisville
Synthesis Of N-Heterocycles Through Cyclization-Triggered Tandem Additions To Alkynes And The Study Of Promoters In Ionic Reactions., Junbin Han
Electronic Theses and Dissertations
Our research mainly focused on three parts related to the rapid construction of N-heterocycles and the search for ionic reaction promoters. First, N-heterocycles of different ring sizes and with different substitution patterns constitute extremely important structure classes (e.g., alkaloids) in the search for bioactivity. A contemporary challenge in organic synthesis is the mapping of new chemical spaces through tandem or cascade reactions in an atom economical fashion. Our strategy to access these biologically important heterocycles is through a cyclization-triggered tandem addition to alkynes catalyzed by readily available alkynophilic coinage metals like copper. In this manner, a variety of functional groups …
Ligand Centered Reactivity Of Metal Stabilized Thiyl Radicals In Solution, Solid And Gaseous Phase.,
2014
University of Louisville
Ligand Centered Reactivity Of Metal Stabilized Thiyl Radicals In Solution, Solid And Gaseous Phase., Rajat Rajat
Electronic Theses and Dissertations
This thesis presents ligand centered reactivity studies of metal stabilized thiyl radicals in solution, solid, and gaseous phases for catalysis and sensing based applications. Chemical oxidation of tris(2-diphenylphosphinebenzenethiolato )ruthenate(II) [Ru -1]- with ferrocenium hexafluorophosphate in the presence of ethylene yields [Ru-1·C,H.]PF6, from addition of the alkene across cis sulfur sites. In the presence of base [Ru-1·C,H.]+ is selectively deprotonated at the pseudoequatorial proton on the carbon a to the sulfur trans to phosphorus, yielding the vinyl metallosulfonium derivative [Ru-1·C,H3]. "H and 31p NMR spectra of [Ru-1'C,H3 ] are temperature dependent, associated with inversion of the sulfur lone pair at the …
Solvent Dependency Of Azobenzene Thermal Relaxation,
2014
McGill University
Solvent Dependency Of Azobenzene Thermal Relaxation, Chris Corkery, Alexis Goulet-Hanssens, Janet R. Belliveau, Mark Cronin-Golomb, Christopher J. Barrett
Chris Corkery
No abstract provided.
Avd Tablet Labs: Virtual Chemistry Laboratories, Honors Chemistry, Grade:10,
2014
Wofford College
Avd Tablet Labs: Virtual Chemistry Laboratories, Honors Chemistry, Grade:10, Caleb A. Arrington, Tina Kanipe, Deep Sangani
Arthur Vining Davis High Impact Fellows Projects
With the increased prevalence of student computers in secondary schools, we created six virtual chemistry laboratories using the virtual lab environment created by Carnegie-Mellon University. Students, using their laptop or tablet computer, can manipulate typical laboratory instrumentation found in an introductory chemistry lab. While not designed to replace traditional wet laboratories, the virtual laboratory environment allows students to examine the nuances of experimental techniques in a low stakes, easily repeatable, environment. The six virtual laboratories developed for this project cover the introductory chemistry subjects of: 1.) density measurements and significant figures, 2.) reaction stoichiometry, 3.) measurements of grams and moles, …
Interfacial Rheology Of Bacterial Biofilms At Air/Water And Oil/Water Interfaces,
2014
University of Missouri, St. Louis
Interfacial Rheology Of Bacterial Biofilms At Air/Water And Oil/Water Interfaces, Patrick Rühs, R. Inglis, Peter Fischer
Biology Department Faculty Works
No abstract provided.
