Physiology Commons^™

Comparison Of Isokinetic Knee Flexion And Extension Strength Between Trained Dancers And Traditional Sport Female Collegiate Athletes, Rachele E. Vogelpohl, Lynn Wolz, Tyler Neltner, Zachariah Burkhardt, Tracey L. Bonner, Hayley M. Ericksen

International Journal of Exercise Science

International Journal of Exercise Science 10(8): 1196-1207, 2017. Traditional sport athletes and dancers experience various injuries while participating in their respective sport. Injury rates, especially to the anterior cruciate ligament (ACL), differ between these populations. Isometric and isokinetic strength and hamstring:quadriceps (H:Q) ratios may help to explain the difference in ACL injury rates between these populations. The purpose of this investigation was to determine the difference in isometric and concentric knee flexion and extension peak torque, and H:Q strength ratios between female dancers and division I collegiate soccer and track and field athletes. Seventeen dancers (20.53±1.51yrs, 65.60±2.06in, 62.29±8.63kg) and 24 …

Resistance Exercise Training On Disease Impact, Pain Catastrophizing And Autonomic Modulation In Women With Fibromyalgia, Alaina Glasgow, Tori M. Stone, J. Derek Kingsley

International Journal of Exercise Science

International Journal of Exercise Science 10(8): 1184-1195, 2017. Women with fibromyalgia (FM) often complain of whole-body pain, and muscle fatigue, which may be related to autonomic dysfunction. Therefore, the purpose of the present study was to investigate the effects of resistance exercise training (RET) on disease impact, pain catastrophizing, and autonomic modulation in women with FM. Women with FM (n=26) and healthy control women (HC: n=9), aged 19-65 yrs, were compared at rest. Women with FM were randomly assigned to a resistance-training group (FM-RT: n=14) or a non-exercising control group (FM-CON: n=12). Women in the FM-RT group underwent 8-weeks of …

The Effect Of Task Complexity Influencing Bilateral Transfer., Dawson J. Kidgell, Ashlyn K. Frazer, Alan J. Pearce

International Journal of Exercise Science

International Journal of Exercise Science 10(8): 1174-1183, 2017. Bilateral transfer is a well-known phenomenon whereby training one limb results in improvement in the untrained homologous limb. However, despite evidence across a range of motor skill paradigms, the influence of motor skill complexity on the magnitude of bilateral transfer has not yet been fully explored. The aim of this preliminary study was to compare bilateral transfer effects between three dexterity tasks with the hypothesis that the complexity of the task, the volume of time training, and the amount of improvement in the trained hand would positively influence bilateral transfer. Using a …

Extreme Conditioning Program Induced Acute Hypotensive Effects Are Independent Of The Exercise Session Intensity, Ramires Alsamir Tibana, Leonardo Mesquita Almeida, Ivo Vieira De Sousa Neto, Nuno Manoel Frade De Sousa, Jeeser Alves De Almeida, Belmiro Freitas De Salles, Claudio Melibeu Bentes, Fabricio Azevedo Voltarelli, Scott Collier, Jonato Prestes

International Journal of Exercise Science

International Journal of Exercise Science 10(8): 1165-1173, 2017. The aim of the study was to determine the acute systolic (SBP) and diastolic (DBP) blood pressure, rating of perceived exertion (RPE) and heart rate (HR) responses following two intense training sessions (24 hours apart). Nine male extreme conditioning program (ECP) practitioners with more than 6 months of experience (age 26.7 ± 6.6 years; body mass 78.8 ± 13.2 kg; body fat 13.5 ± 6.2 %) completed two experimental ECP sessions. Cardiovascular variables were measured before, immediately after and every 15 min during a 45 min recovery following each experimental session. Compared …

The Relative Age Effect In Soccer: An Analysis Of The U20 Libertadores Cup, Fabio A D Campos, Leandra C B Campos, Idico L. Pellegrinotti, Miguel A. Gómez

International Journal of Exercise Science

International Journal of Exercise Science 10(8): 1157-1164, 2017. The year of birth is used as a criterion for grouping the competitive categories in various sports. Young players that were born in the early months of the calendar can have a benefit during their formative process, since they have higher chronological age and, consequently, are more likely to be in more advanced stages of biological maturation. The aim of this study was to evaluate the Relative Age Effect (RAE) in the U-20 Libertadores Cup. The sample consisted of 228 young players belonging to 12 clubs (ten different countries) who vied for …

Effect Of Seat Tube Angle And Exercise Intensity On Muscle Activity Patterns In Cyclists, Will Duggan, Bernard Donne, Neil Fleming

International Journal of Exercise Science

International Journal of Exercise Science 10(8): 1145-1156, 2017. Previous studies have reported improved efficiency at steeper seat tube angle (STA) during ergometer cycling; however, neuromuscular mechanisms have yet to be fully determined. The current study investigated effects of STA on lower limb EMG activity at varying exercise intensities. Cyclists (n=11) were tested at 2 workloads; 160W and an individualised workload (IWL) equivalent to lactate threshold (T_Lac) minus 10%δ (derived from maximal incremental data), using 3 STA (70, 75 and 80°). Electromyographic data from Vastus Medialis (VM), Rectus Femoris (RF), Vastus Lateralis (VL) and Biceps Femoris (BF) were assessed. …

Exertional Observation In Adults Performing Intermittent Treadmill Walking And Running, Michael Gallagher Jr., Robert J. Robertson, Fredric L. Goss, Irene Kane, Elizabeth F. Nagle, Kathryn A. Tessmer

International Journal of Exercise Science

International Journal of Exercise Science 10(8): 1130-1144, 2017. The present investigation examined the Adult OMNI Walk-Run Scale for use by an independent observer to rate an individual’s perception of exertion during intermittent treadmill walking and running. Forty (22.4 ± 2.9 yrs) recreationally active males (n = 18) and females (n = 22) completed three 5-min intermittent bouts of treadmill exercise. The exercise bouts were a level walk (LW; 4.0 km∙hr^-1, 0% grade), hill walk (HW; 5.6 km∙hr^-1, 5% grade), and run (R; 8 km∙hr^-1, 2.5% grade). Each bout was separated by a 5-min recovery …

An Assessment Of Sedentary Time Among Undergraduate Students At A Canadian University, Marc S. Moulin, Jennifer D. Irwin

International Journal of Exercise Science

International Journal of Exercise Science 10(8): 1116-1129, 2017. The purpose of this study was to calculate a total daily sedentary time for the undergraduate population at a large urban Canadian University and investigate student perceptions of the facilitators and barriers to engaging in a less sedentary lifestyle. A sample of 335 participants responded to an online questionnaire that included the SIT-Q and open-ended questions, with 102 providing sufficient data to be included in the quantitative analysis and 145 in the qualitative analysis. Students spent an average of 11.88 ± 3.46 hrs/day engaged in sedentary behaviors. Three themes were identified as …

The Effect Of Biofeedback Training On One Repetition Maximum Chest Press Performance, Joann C. Wakefield, Amber M. Shipherd

International Journal of Exercise Science

International Journal of Exercise Science 10(8): 1105-1115, 2017. Biofeedback is a method of controlling normally automatic bodily functions by monitoring and training to acquire voluntary control over them (13). The purpose of this study was to determine if a heart-rate variability training program utilizing the emWave biofeedback device could increase performance on a simple strength task. Participants (n = 18) were randomly assigned to one of three groups and data were collected for a period of seven weeks. Data collection consisted of participants receiving training (experimental and alternate groups) or no training (control group), followed by a chest press one …

The Role Of Social Physique Anxiety, Social Support, And Perceived Benefits And Barriers To Exercise In An All-Female Fitness Camp Intervention, Lauren Easton, Brandonn Harris, Daniel Czech, Ashley D. Walker

International Journal of Exercise Science

International Journal of Exercise Science 10(8): 1094-1104, 2017. Only 20.3% of American adults meet the Center for Disease Control’s minimum recommended volume of exercise for anaerobic and aerobic physical activities (11). This small proportion representing those who reach the suggested physical activity levels is an issue of concern for researchers and practitioners in health-related disciplines; further, the Centers for Disease Control report that physical inactivity levels are even higher for women than those of males. In 2008, only 42% of women 18 years and older met the minimal federal levels of aerobic activity through leisure-time aerobic activity (2). This statistic …

Examining The Electrical Excitation, Calcium Signaling, And Mechanical Contraction Cycle In A Heart Cell, Kristen Deetz, Nygel Foster, Darius Leftwich, Chad Meyer, Shalin Patel, Carlos Barajas, Matthias K. Gobbert, Zana Coulibaly

Spora: A Journal of Biomathematics

As the leading cause of death in the United States, heart disease has become a principal concern in modern society. Cardiac arrhythmias can be caused by a dysregulation of calcium dynamics in cardiomyocytes. Calcium dysregulation, however, is not yet fully understood and is not easily predicted; this provides motivation for the subsequent research. Excitation-contraction coupling (ECC) is the process through which cardiomyocytes undergo contraction from an action potential. Calcium induced calcium release (CICR) is the mechanism through which electrical excitation is coupled with mechanical contraction through calcium signaling. The study of the interplay between electrical excitation, calcium signaling, and mechanical …

Physiological And Biomechanical Responses Of Highly Trained Distance Runners To Lower-Body Positive Pressure Treadmill Running, Kyle Barnes, Jessica N. Janecke

Open Access Publishing Support Funded Articles

Background: As a way to train at faster running speeds, add training volume, prevent injury, or rehabilitate after an injury, lower-body positive pressure treadmills (LBPPT) have become increasingly commonplace among athletes. However, there are conflicting evidence and a paucity of data describing the physiological and biomechanical responses to LBPPT running in highly trained or elite caliber runners at the running speeds they habitually train at, which are considerably faster than those of recreational runners. Furthermore, data is lacking regarding female runners’ responses to LBPPT running. Therefore, this study was designed to evaluate the physiological and biomechanical responses to LBPPT …

Temperature Effects On An Axon’S Ability To Maintain Phasing Of A Rhythmic Motor System, Marissa Elaine Cruz

Theses and Dissertations

The precise timing of action potentials generated in the nervous system is crucial for generating adequate behavior. Once generated, action potentials travel along axons towards the neurons or muscles they innervate. Axons are also responsible for preserving the temporal fidelity of the generated action potentials. One challenge axons face is that they can be of considerable length, and exposed to changes in internal and external conditions. Temperature fluctuations, for example, affect the ion channels that generate and propagate action potentials causing changes in action potential speed. It is unclear if, and how, the timing of action potentials can be preserved …

Glomerular Hyperfiltration And Hypertension In Diabetes, Jie Zhang

USF Tampa Graduate Theses and Dissertations

In the present study, we investigated the pathophysiological mechanisms of the hemodynamic alteration in diabetes. Glomerular hyperfiltration occurs in the early stage of diabetes mellitus and has been recognized to promote the pathogenesis of diabetic nephropathy. We determine the role of TGF response and the vascular tone of Af-Art in diabetic hyperfiltration and we found that 1) tubular high glucose directly activates NOS1 and increases NO generation in the macula densa, which inhibits TGF response and increases GFR; 2) high glucose dilates renal Af-Art through GLUT1 and mediated by NOS3-derived NO generation; 3) in diabetes, blunted TGF mediated by NOS1 …

Current Research And Statistical Practices In Sport Science And A Need For Change, Jake R. Bernards, Kimitake Sato, G. Gregory Haff, Caleb D. Bazyler

ETSU Faculty Works

Current research ideologies in sport science allow for the possibility of investigators producing statistically significant results to help fit the outcome into a predetermined theory. Additionally, under the current Neyman-Pearson statistical structure, some argue that null hypothesis significant testing (NHST) under the frequentist approach is flawed, regardless. For example, a p-value is unable to measure the probability that the studied hypothesis is true, unable to measure the size of an effect or the importance of a result, and unable to provide a good measure of evidence regarding a model or hypothesis. Many of these downfalls are key questions researchers strive …

Neuronal Degeneration And Short-Term Memory Impairment After Tbi, Obiamaraije Igwe

Posters-at-the-Capitol

Traumatic brain injury (TBI) was associated with impaired short-term memory with causes of vehicle accidents and falls. Protein plaques containing fibrinogen (Fg), are associated with memory loss. After TBI, Fg in blood was higher than normal (>~2 mg/ml), which resulted in increased Fg in extravascular space. Therefore, Fg bonded to its endothelial receptor intercellular adhesion molecule-1 (ICAM-1). Fg then interacted with cellular prion protein (PrPC), which had a strong effect on the loss of memory and cognition. Mechanisms of Fg and PrPC complex formation and its functional implication are not known. This present study tested the level of Fg-PrPC …

Multigeneration Effects Of Chronic Exposure To Polycyclic Aromatic Hydrocarbons In Gulf Killifish (Fundulus Grandis), Andrea Yammine

LSU Master's Theses

The goal of this study was to examine potential adaptation within two generations of Gulf killifish exposed to polycyclic aromatic hydrocarbons (PAH) while also investigating the use of mucus as an effective and non-lethal alternative to determine concentrations of 11-ketotestosterone (11-KT) and vitellogenin (VTG) of F. grandis. Multiple biomarkers were used to assess adaptation within these fish, such as lysozyme (enzyme critical in innate immunity), and 11-ketotestosterone and vitellogenin (endocrine hormones often affected by PAHs).

Mucal concentrations of 11-KT and VTG were determined and evaluated for effectiveness through comparative assays with blood plasma. This method was then applied to …

Primary Upper Urinary Tract Small Cell Carcinoma: A Case Series And Literature Review, Patrick J. Hensley, Amul A. Bhalodi, Shubham Gupta

Urology Faculty Publications

Background: Primary upper urinary tract small cell carcinoma (SCC) is exceedingly rare with < 30 cases reported in the literature. Little is known about the incidence, diagnosis, treatment, and outcomes in these patients. We present a series of three patients with primary upper tract SCC.

Case Presentation: Patient 1 is an 89-year-old Caucasian male who presented with hydroureteronephrosis and a mass in the proximal right ureter. Biopsy revealed SCC. Without further intervention, the patient died 2 months after his diagnosis. Patient 2 is a 67-year-old Caucasian female who underwent left laparoscopic nephroureterectomy for primary distal ureteral SCC, pT4N1M0. She developed lymphadenopathy and completed external beam radiation to the pelvis and four courses of cisplatin-based chemotherapy. She died from metastatic disease 7 months after diagnosis. Patient 3 is a 45-year-old female who underwent …

Abnormal Contractility In Human Heart Myofibrils From Patients With Dilated Cardiomyopathy Due To Mutations In Ttn And Contractile Protein Genes, Petr G. Vikhorev, Natalia Smoktunowicz, Alex B. Munster, O'Neal Copeland, Sawa Kostin, Cecile Montgiraud, Andrew E. Messer, Mohammad R. Toliat, Amy Li, Cristobal G. Dos Remedios, Sean Lal, Cheavar A. Blair, Kenneth S. Campbell, Maya E. Guglin, Ralph Knoll, Steven B. Marston

Physiology Faculty Publications

Dilated cardiomyopathy (DCM) is an important cause of heart failure. Single gene mutations in at least 50 genes have been proposed to account for 25–50% of DCM cases and up to 25% of inherited DCM has been attributed to truncating mutations in the sarcomeric structural protein titin (TTNtv). Whilst the primary molecular mechanism of some DCM-associated mutations in the contractile apparatus has been studied in vitro and in transgenic mice, the contractile defect in human heart muscle has not been studied. In this study we isolated cardiac myofibrils from 3 TTNtv mutants, and 3 with contractile protein mutations (TNNI3 …

Pharmaceutical And Natural (Exercise) Mechanisms To Mitigate The Negative Impact Of Ptsd And Chronic Stress On Synaptic Plasticity And Memory, Roxanne M. Miller

Theses and Dissertations

Synapses can be altered due to experiences in a process called synaptic plasticity, which causes memory formations. Synapses can be strengthened through methods known as long-term potentiation (LTP) or weakened through long-term depression (LTD). Stresses can cause changes by altering synapses through either LTP or LTD. Rats were used to study the effects of post-traumatic stress disorder (PTSD)-like symptoms and a prophylactic treatment using pharmaceuticals. The first model used was the single prolonged stress (SPS) with two weeks of chronic light, which was not as effective for causing changes in synaptic plasticity. The second model, seven days of social defeat …

Calpain Inhibition Attenuates Adipose Tissue Inflammation And Fibrosis In Diet-Induced Obese Mice, Latha Muniappan, Aida Javidan, Weihua Jiang, Shayan Mohammadmoradi, Jessica J. Moorleghen, Wendy S. Katz, Anju Balakrishnan, Deborah A. Howatt, Venkateswaran Subramanian

Saha Cardiovascular Research Center Faculty Publications

Adipose tissue macrophages have been proposed as a link between obesity and insulin resistance. However, the mechanisms underlying these processes are not completely defined. Calpains are calcium-dependent neutral cysteine proteases that modulate cellular function and have been implicated in various inflammatory diseases. To define whether activated calpains influence diet-induced obesity and adipose tissue macrophage accumulation, mice that were either wild type (WT) or overexpressing calpastatin (CAST Tg), the endogenous inhibitor of calpains were fed with high (60% kcal) fat diet for 16 weeks. CAST overexpression did not influence high fat diet-induced body weight and fat mass gain throughout the study. …