Open Access. Powered by Scholars. Published by Universities.®

Laboratory and Basic Science Research Commons™

Open Access. Powered by Scholars. Published by Universities.®

Discipline
Institution
Keyword
Publication Year
Publication
Publication Type
File Type

Articles 901 - 930 of 1395

Full-Text Articles in Laboratory and Basic Science Research

The Development Of Skeletal Muscle In Young Horses: An Ultrasonography And Satellite Cell Approach, Emma K. Lavigne May 2015

The Development Of Skeletal Muscle In Young Horses: An Ultrasonography And Satellite Cell Approach, Emma K. Lavigne

Honors Scholar Theses

Muscle growth in young horses is characterized by an increase in muscle cross-sectional area, which can be accomplished through the activation and differentiation of satellite cells. Satellite cells can be stimulated or inhibited in response to different cytokines and growth factors and are key mediators of muscle hypertrophy and regeneration. The aim of this study was to investigate the growth of the longissimus dorsi (LD) muscle in horses under 5 years of age and to obtain preliminary data on satellite cell behavior in foals. The area, width, height, and subcutaneous fat were measured using ultrasonography at 6-month increments over the …

Go to article

Effects Of Pre-Release Physical Stressors On Post-Release Success Of Hatchery-Reared Spotted Seatrout, Taylor Westbrook Guest May 2015

Effects Of Pre-Release Physical Stressors On Post-Release Success Of Hatchery-Reared Spotted Seatrout, Taylor Westbrook Guest

Master's Theses

Alteration of habitat associated with coastal development and increased demand for food and recreation can result in the depletion of fisheries resources such as the Spotted Seatrout (Cynoscion nebulosus), the Gulf of Mexico’s most popular recreational fish. Stock enhancement, or the release of cultured fish to supplement wild populations, is one potential tool for managing important fisheries resources. Although much effort has gone into marine stock enhancement, the effectiveness of stocking is not well established, and techniques for ensuring success have not been developed. Although the basic biology of the Spotted Seatrout is well known, comparatively little is known about …

Go to article

Multilevel Deregulation Of Survival Mechanisms In Npm-Alk+ T-Cell Lymphoma, Deeksha Vishwamitra May 2015

Multilevel Deregulation Of Survival Mechanisms In Npm-Alk+ T-Cell Lymphoma, Deeksha Vishwamitra

Dissertations and Theses (Open Access)

The anaplastic lymphoma kinase (ALK) is a single chain transmembrane receptor tyrosine kinase that belongs to the insulin receptor superfamily. Other members of this superfamily include the insulin receptor (IR), type I insulin-like growth factor receptor (IGF-IR), and the leukocyte tyrosine kinase. The common structural finding among these tyrosine kinases is the YXXXYY motif present within their respective tyrosine kinase domains. Binding of its ligands causes ALK receptor homodimerization and protein kinase activation. ALK has been previously shown to play a significant role during early developmental stages. In human embryos, the expression of ALK is mainly seen in …

Go to article

Pathological Effects Of Repeated Concussive Tbi In Mouse Models: Periventricular Damage And Ventriculomegaly, Richard H. Wolferz Jr. May 2015

Pathological Effects Of Repeated Concussive Tbi In Mouse Models: Periventricular Damage And Ventriculomegaly, Richard H. Wolferz Jr.

Honors Scholar Theses

Repeated concussive traumatic brain injury (rcTBI) is the most prominent form of head injury affecting the brain, with an estimated 1.7 million Americans affected each year (Kuhn 2012). Neurologists have been concerned about the danger of repeated head impacts since the 1920’s, but researchers have only begun to understand the long-term effects of rcTBI (McKee 2009). Although symptoms can be as mild as dizziness, current research suggests that multiple concussions can lead to a progressive degenerative brain disease known as chronic traumatic encephalopathy (CTE) (Luo 2008, McKee 2009, Kane 2013). Research on the brain is just beginning to scratch the …

Go to article

Developing A Catalog Of Socio-Sexual Behaviors Of Beluga Whales ( Delphinapterus Leucas ) In The Care Of Humans, Heather M. Hill, Sarah Dietrich, Deirdre Yeater, Mariyah Mckinnon, Malin Miller, Steve Aibel, Al Dove May 2015

Developing A Catalog Of Socio-Sexual Behaviors Of Beluga Whales ( Delphinapterus Leucas ) In The Care Of Humans, Heather M. Hill, Sarah Dietrich, Deirdre Yeater, Mariyah Mckinnon, Malin Miller, Steve Aibel, Al Dove

Psychology Faculty Publications

The repertoire of socio-sexual and sexual behaviors of cetaceans is relatively unknown. The purpose of the current study was to advance the existing knowledge of socio-sexual behavior of beluga whales through the development of a behavioral catalog that lists the full repertoire of sexual and socio-sexual behaviors. A behavioral catalog was developed initially from 800 hours of observations, collected across a 7-year period from 11 belugas ranging in age (birth to 30+ years), sex, and social groupings. Using this behavioral catalog, observations of eight additional belugas housed between two other facilities were coded for socio-sexual and sexual behaviors. Socio-sexual and …

Go to article

The Effect Of Red Maple Leaf Toxicosis On Reduced Glutathione Levels In Equine Erythrocytes In Vitro, Madeline A. Rohl Apr 2015

The Effect Of Red Maple Leaf Toxicosis On Reduced Glutathione Levels In Equine Erythrocytes In Vitro, Madeline A. Rohl

Undergraduate Honors Thesis Projects

Red maple leaf toxicosis is an equine blood disorder resulting from the consumption of wilted red maple (Acer rubrum L.) leaves by horses. Compounds within the leaves of red maple have oxidative effects on equine erythrocytes and can cause hemolysis of erythrocytes, the conversion of hemoglobin to methemoglobin, and the production of Heinz bodies. Reduced glutathione is important in the protection of equine erythrocytes from these oxidative events; however, in the presence of red maple toxin, glutathione is rapidly oxidized and is unavailable. The objective of this study is to determine whether the presence of vitamin C alters levels …

Go to article

Microbial Communities Of The Providence River, Jacqueline Kratch Apr 2015

Microbial Communities Of The Providence River, Jacqueline Kratch

Honors Projects in Science and Technology

The Providence River has been industrialized for over one-hundred years. Industries such as oil storage and metal recycling facilities have left high levels of pollutant metals, including lead (Pb), in the soil and water. The elevated Pb concentrations in these environments influence the selection of Pb resistance mechanisms in the bacterial community1. One mechanism of heavy metal resistance is the Pb efflux pump, consisting of proteins in the cell membrane that aid in the transport of Pb out of the cell2. In this study we investigated the co-occurrence of Pb efflux pumps and antibiotic efflux pumps in bacteria from Pb …

Go to article

Use And Misuse Of Material Transfer Agreements: Lessons In Proportionality From Research, Repositories, And Litigation, Tania M. Bubela, Jenilee Guebert, Amrita Mishra Feb 2015

Use And Misuse Of Material Transfer Agreements: Lessons In Proportionality From Research, Repositories, And Litigation, Tania M. Bubela, Jenilee Guebert, Amrita Mishra

Office of the Provost

Material transfer agreements exist to facilitate the exchange of materials and associated data between researchers as well as to protect the interests of the researchers and their institutions. But this dual mandate can be a source of frustration for researchers, creating administrative burdens and slowing down collaborations. We argue here that in most cases in pre-competitive research, a simple agreement would suffice; the more complex agreements and mechanisms for their negotiation should be reserved for cases where the risks posed to the institution and the potential commercial value of the research reagents is high.

Go to article

Genome Engineering To Create Dominant Alleles In Caenorhabditis Elegans Using Crispr-Cas9 Technology, Abrar Sulaimani Jan 2015

Genome Engineering To Create Dominant Alleles In Caenorhabditis Elegans Using Crispr-Cas9 Technology, Abrar Sulaimani

Graduate School of Biomedical Sciences Theses and Dissertations

Many investigators have being using CRISPR-Cas9 as a method of genome engineering because it is easy, accurate and fast. This technique has been used to modify the genomes of a wide variety of organisms, including the nematode Caenorhabditis elegans (C. elegans). The short life cycle and ease of introducing exogenous plasmids make C. elegans an ideal system for advancing this technique. My thesis had two aims that focused on developing methods to create dominant alleles in C. elegans. Genetic modifications like precise deletion and insertions into a locus of chromosome are technically challenging. Additionally, although there are several ways of …

Go to article

Validating A Method For Measuring Protein Domain And Lipid Binding Interactions Using Luciferase Fusion Proteins, Dezaray E. Thoen Jan 2015

Validating A Method For Measuring Protein Domain And Lipid Binding Interactions Using Luciferase Fusion Proteins, Dezaray E. Thoen

Honors Capstones

Capstone submitted as a graduation requirement for the BSU Honors Program.

Go to article

The Significance Of Crispr/Cas9-Directed Cul3 Knockout On Human Colorectal Cancer Cells, Zoe A. Lautz Jan 2015

The Significance Of Crispr/Cas9-Directed Cul3 Knockout On Human Colorectal Cancer Cells, Zoe A. Lautz

Departmental Honors Projects

Cancer, the second leading cause of death in the US, is caused by mutations in select genes that alter cellular function leading to uncontrolled proliferation. Understanding the specific genes that drive cancer can lead to the generation of novel cancer therapies. To identify novel genes that drive cancer in the colon (CRC), lungs, and ovaries in mice, Starr et al. employed a transposon-based insertional mutagenesis system. One of the genes identified, APC, is mutated in 70-80% of human CRCs. CUL3, suspected to be a general driver gene, was discovered in the lung cancer screen. CUL3 was analyzed for its role …

Go to article

Abiotic Habitat Preferences Of Age-0 Paddlefish In Lake Sakakawea, North Dakota During Late Summer, Derek Dufault Jan 2015

Abiotic Habitat Preferences Of Age-0 Paddlefish In Lake Sakakawea, North Dakota During Late Summer, Derek Dufault

Journal of Earth and Life Science

Since the early 1990’s, surface visual counts along transects have been conducted annually, allowing for estimates of relative abundance and year-class strength of age-0 paddlefish Polyodon spathula on the upper portions of Lake Sakakawea, North Dakota. This study focuses on the annual visual surface count data collected over an eleven year period from 2004-2014. More specifically it focuses on abiotic habitat factors (Secchi depth, water depth, and water temperature) and how they relate to age-0 paddlefish locations in late summer. Understanding habitat use during early life stages is imperative, yet to date, there is very limited knowledge available regarding the …

Go to article

Influence Of Depth And Retrieval Speed On Yellow Perch Barotrauma Recovery Time In Winter, Bradley J. Klingsheim Jan 2015

Influence Of Depth And Retrieval Speed On Yellow Perch Barotrauma Recovery Time In Winter, Bradley J. Klingsheim

Journal of Earth and Life Science

Physoclistous fish are often affected by barotrauma because the swim bladder is not connected to the esophagus. Barotrauma is increasingly being used in assessing mortality in fish brought from deep water. Barotrauma is the physical damage that occurs because of the over inflation of the gas bladder resulting from a rapid decrease in ambient pressure. The two important factors influencing barotrauma effects are water depth and decompression. In this study, two experiments were conducted on yellow perch (Perca flavescens) at three depth locations on Grace Lake, Bemidji, Minnesota. Fish were measured for barotrauma recovery time (s) following capture by hook …

Go to article

Elucidating The Role Of Endogenous Electric Fields In Regulating The Astrocytic Response To Injury In The Mammalian Central Nervous System, Matthew L. Baer Jan 2015

Elucidating The Role Of Endogenous Electric Fields In Regulating The Astrocytic Response To Injury In The Mammalian Central Nervous System, Matthew L. Baer

Theses and Dissertations

Endogenous bioelectric fields guide morphogenesis during embryonic development and regeneration by directly regulating the cellular functions responsible for these phenomena. Although this role has been extensively explored in many peripheral tissues, the ability of electric fields to regulate wound repair and stimulate regeneration in the mammalian central nervous system (CNS) has not been convincingly established. This dissertation explores the role of electric fields in regulating the injury response and controlling the regenerative potential of the mammalian CNS. We place particular emphasis on their influence on astrocytes, as specific differences in their injury-induced behaviors have been associated with differences in the …

Go to article

Carnivore Diet Identification Through Scat And Genetic Analysis In Namibia, Africa, Alicia J. Walsh Jan 2015

Carnivore Diet Identification Through Scat And Genetic Analysis In Namibia, Africa, Alicia J. Walsh

Honors Theses and Capstones

Worldwide the cheetah population is declining making them Africa’s most endangered large cat. Namibia, Africa currently has the largest population of cheetahs in the world. During the summer of 2014, I did scat analysis of carnivores on the property of the Cheetah Conservation Fund (CCF) in Namibia in order to better understand the predators that compete with the cheetah and how the ecosystem works as a whole. I worked at CCF for nine weeks to analyze the diets of carnivores in the area through genetic and scat analysis. Analyzing carnivore feces would ultimately identify the diet of various carnivores in …

Go to article

The Phytotronist And The Phenotype: Plant Physiology, Big Science, And A Cold War Biology Of The Whole Plant., David Munns Jan 2015

The Phytotronist And The Phenotype: Plant Physiology, Big Science, And A Cold War Biology Of The Whole Plant., David Munns

Publications and Research

This paper describes how, from the early twentieth century, and especially in the early Cold War era, the plant physiologists considered their discipline ideally suited among all the plant sciences to study and explain biological functions and processes, and ranked their discipline among the dominant forms of the biological sciences. At their apex in the late-1960s, the plant physiologists laid claim to having discovered nothing less than the “basic laws of physiology.” This paper unwraps that claim, showing that it emerged from the construction of monumental big science laboratories known as phytotrons that gave control over the growing environment. Control …

Go to article

Regulation Of Pancreatic Β-Cell Function By The Renin-Angiotensin System In Type 2 Diabetes, Robin C. Shoemaker Jan 2015

Regulation Of Pancreatic Β-Cell Function By The Renin-Angiotensin System In Type 2 Diabetes, Robin C. Shoemaker

Theses and Dissertations--Pharmacology and Nutritional Sciences

Diet-induced obesity promotes type 2 diabetes (T2D). Drugs that inhibit the renin-angiotensin system (RAS) have been demonstrated in clinical trials to decrease the onset of T2D. Previously, we demonstrated that mice made obese from chronic consumption of a high-fat (HF) diet have marked elevations in systemic concentrations of angiotensin II (AngII). Pancreatic islets have been reported to possess components of the renin-angiotensin system (RAS), including angiotensin type 1a receptors (AT1aR), the primary receptor for AngII, and angiotensin converting-enzyme 2 (ACE2), which negatively regulates the RAS by catabolizing AngII to angiotensin-(1-7) (Ang-(1-7)). These two opposing proteins have been implicated in the …

Go to article

Assessing The Contributions Of Two Stocked Strains On A Minnesota-Wisconsin Border Water, Douglas Zentner Jan 2015

Assessing The Contributions Of Two Stocked Strains On A Minnesota-Wisconsin Border Water, Douglas Zentner

Journal of Earth and Life Science

Stocking has long been used as a management tool in the United States even though many of its effects remain cryptic. Past comparisons between stocked strains were generally based on the survival and growth rates of physically marked individuals. More recently the use of genetic markers to assess contributions of stocked individuals has been employed by fisheries managers. Using 13 microsatellite markers we assessed the contributions of two muskellunge (Esox masquinongy) strains (Wisconsin and Leech) stocked into the St. Louis River Estuary. Ancestry in the adult samples remained relatively constant with differences only observed between the 2008 and …

Go to article

Using Wild I.D. As A Reliable Source For Mark And Recapture Studies On Northern Pike (Esox Lucius), Martin Evans Jan 2015

Using Wild I.D. As A Reliable Source For Mark And Recapture Studies On Northern Pike (Esox Lucius), Martin Evans

Journal of Earth and Life Science

Mark and recapture studies are a very popular method fisheries biologists use to assess certain fish populations in lakes. This process can be very labor intensive and expensive. Wild I.D. is free software developed by Dartmouth College that uses SIFT program to find unique features in photographs. Initially developed for identification of African land mammals the program gives each photo a score and percent match to other photos. Northern pike were used in this study to determine if the program can recognize simulated recapture events. Photos of sample fish were taken at two separate locations, the photos were then copied …

Go to article

Juvenile Chinook Salmon Diet In Comparison To Invertebrate Drift In The Merced River, California, Tyler Orgon Jan 2015

Juvenile Chinook Salmon Diet In Comparison To Invertebrate Drift In The Merced River, California, Tyler Orgon

Journal of Earth and Life Science

Diets and habitat types of salmonids have been widely studied in disturbed streams and rivers. The Merced River in California has a long history of flooding, damming, levee failures, and channel reconstruction events that has disrupted the aquatic ecosystem. This 30 day study was conducted in the Robinson Reach of the Merced River using juvenile Chinook salmon (Oncorhynchus tshawtscha). The objectives were to try and understand if juvenile Chinook salmon were selecting certain invertebrate species, determine if there were any differences in diets between habitat types, and determine whether diets and drift samples were different. Diets consisted of …

Go to article

Effects Of Cooler Northern Waters On Growth Rates In Bluegill And Pumpkinseed Sunfish, Alec Spurbeck Jan 2015

Effects Of Cooler Northern Waters On Growth Rates In Bluegill And Pumpkinseed Sunfish, Alec Spurbeck

Journal of Earth and Life Science

The Centrarchidae family range spans all across the United States making them a favorite target for many recreational anglers. In northern Minnesota, most water bodies do not reach optimal growth temperatures for the sunfishes, putting them right on the edge of their suitable range and potentially slowing overall growth. Therefore, the main objectives of this study were to 1) determine if sunfish growth rates respond to the severity of winter and 2) investigate growth differences between two sunfish species. Growth rates of bluegill (Lepomis macrochirus) and pumpkinseed (Lepomis gibbosus) were estimated from Big Sugar Bush Lake, …

Go to article

Spatial And Temporal Factors Influencing Northern Pike Fry Density Estimates, Nate Stott Jan 2015

Spatial And Temporal Factors Influencing Northern Pike Fry Density Estimates, Nate Stott

Journal of Earth and Life Science

The Tamarac River in northern Minnesota is an important spawning site for northern pike (Esox lucius) in the Red Lake system. However, little is known about fry production in the river. This study investigates migration densities and spatial and temporal factors influencing northern pike fry density estimates. Northern pike fry were collected with drift nets between 28 May and 4 June 2014. Thirty northern pike fry were randomly selected to have total length measured from each sample. Northern pike fry were observed in the first sample day. Northern pike fry density maxima occurred on 29 May at midnight …

Go to article

A Genetic Based Approach To Management And Stocking Of Muskellunge, Douglas Zentner Jan 2015

A Genetic Based Approach To Management And Stocking Of Muskellunge, Douglas Zentner

Journal of Earth and Life Science

Fish stocking has long been used as a management tool among fisheries biologists and continues to be met with popular public opinion. Despite perceived simplicity, the full effects of stocking remain cryptic for many fish populations. Stocking has frequently been used to maintain or establish successful muskellunge (Esox masquinongy) populations. Coupled with other management practices the Minnesota Department of Natural Resources (MNDNR) has established Minnesota as a premier muskellunge fishery. From 1958 to 2012 the MNDNR stocked three strains of muskellunge in Big Mantrap Lake, MN. The first from Shoepack Lake, MN (hereafter Shoepack-strain) was used until the …

Go to article

Behavioral Response Of Pacific Lamprey (Entosphenus Tridentatus) To Predator Odors, Laurie L. Porter Jan 2015

Behavioral Response Of Pacific Lamprey (Entosphenus Tridentatus) To Predator Odors, Laurie L. Porter

All Master's Theses

Pacific lamprey (Entosphenus tridentatus), a species facing serious threats to their existence, experience a number of challenges in reaching their desired spawning grounds during the adult migratory phase, and predators are suspected to be one of these challenges. Understanding if Pacific lamprey respond to predator odorants may provide a management tool for use in conjunction with attractants in guiding lamprey to suitable spawning habitat and deterring them from poor habitat. Previous research has failed to explore Pacific lamprey response to predator odorants, although much research exists on attractant odorants. In our study, we tested Pacific lamprey response to …

Go to article

Food Fish Identification From Dna Extraction Through Sequence Analysis, Heather E. Hallen-Adams Jan 2015

Food Fish Identification From Dna Extraction Through Sequence Analysis, Heather E. Hallen-Adams

Department of Food Science and Technology: Faculty Publications

This experiment exposed third and fourth year undergraduates and graduate students taking a course in advanced food analysis to DNA extraction, polymerase chain reaction (PCR), and DNA sequence analysis. Students provided their own fish sample, purchased from local grocery stores, and the class as a whole extracted DNA, which was then subjected to PCR, gel electrophoresis and Sanger sequencing. Students retrieved their sequences and identified their fish using the NCBI BLAST nucleotide database. Slightly more than half of the samples yielded sequences identical or close to expected (based on the identification of the fish on the packaging); some other samples …

Go to article

Electrophysiological And Behavioral Working Memory Differences Between Musicians And Non-Musicians, Benjamin P. Richardson Jan 2015

Electrophysiological And Behavioral Working Memory Differences Between Musicians And Non-Musicians, Benjamin P. Richardson

All Master's Theses

The current study examines the P300 brainwave and working memory differences between musicians and non-musicians. Differences in aspects of recorded electrical brain activity have been used to quantify differences in updating processes of working memory possibly related to differences in amount of music experience. The current study is designed to partially replicate and enhance a method previously implemented in research describing how music experience may be associated with differences in visual processing as well auditory working memory and executive function. Behavioral data were collected using six standardized subtest measures of the TOMAL – II, followed by ERP recordings during a …

Go to article

Designing Anthradithiophene Derivatives Suitable For Applications In Organic Electronics And Optoelectronics, Rawad Kamal Hallani Jan 2015

Designing Anthradithiophene Derivatives Suitable For Applications In Organic Electronics And Optoelectronics, Rawad Kamal Hallani

Theses and Dissertations--Chemistry

Anthradithiophene (ADT) derivatives have proven to be a front-runner in the world of small molecule semiconductors for organic electronics and optoelectronics. This is mainly due to the improved stability, easy tuning of chemical and physical properties, and impressive device performance that these molecules possess, especially in organic field effect transistors (OFET) and organic photovoltaics (OPV). The second chapter of this dissertation shows that reducing the amount of alkylsilylethynyl groups, used for functionalizing and solubilizing the ADT backbone, does alter the chemical, physical and crystallographic properties of ADTs. These changes offer the opportunity to study and observe different intermolecular interactions as …

Go to article

Evaluation Of The Developmental Toxicity Of Lead In The Danio Rerio Body, Nicole M. Roy, Sarah Dewolf, Bruno Carneiro Jan 2015

Evaluation Of The Developmental Toxicity Of Lead In The Danio Rerio Body, Nicole M. Roy, Sarah Dewolf, Bruno Carneiro

Biology Faculty Publications

Lead has been utilized throughout history and is widely distributed and mobilized globally. Although lead in the environment has been somewhat mitigated, the nature of lead and its extensive uses in the past prohibit it from being completely absent from our environment and exposure to lead is still a public health concern. Most studies regarding lead toxicity have focused on the brain. However, little is found in the literature on the effects of lead in other tissues. Here, we utilize the zebrafish model system to investigate effects of lead exposure during early developmental time windows at 24, 48 and 72 …

Go to article

Estimates Of Persistent Inward Current In Human Motor Neurons During Postural Sway, Ryan Foley, Jayne M. Kalmar Dr. Jan 2015

Estimates Of Persistent Inward Current In Human Motor Neurons During Postural Sway, Ryan Foley, Jayne M. Kalmar Dr.

Theses and Dissertations (Comprehensive)

Persistent inward current (PIC) is a membrane property critical for increasing gain of motor neuron output. In humans, most estimates of PIC are made from plantarflexor or dorsiflexor motor units with the participant in a seated position with the knee flexed. This seated and static posture neglects the task-dependent nature of the monoaminergic drive that modulates PIC activation. Seated estimates may drastically underestimate the amount of PIC that occurs in human motor neurons during functional movement. The current study estimated PIC using the conventional paired motor unit technique which uses the difference between reference unit firing frequency at test unit …

Go to article

Determining The Critical Window Of Influence Of Pcb Perinatally On Behavioral And Hormonal Development In Sprague-Dawley Rat Pups, Natalie Sommerville, Lee A. Meserve, Howard C. Cromwell Dec 2014

Determining The Critical Window Of Influence Of Pcb Perinatally On Behavioral And Hormonal Development In Sprague-Dawley Rat Pups, Natalie Sommerville, Lee A. Meserve, Howard C. Cromwell

Honors Projects

Polychlorinated biphenyls (PCB) had widespread use in the United States in commercial manufacturing in the United States until the late 1970s. Even though they were banned, measurable amounts can still be found in the environment and food sources. PCB has known effects on altering hormone development and behavior in the species Rattus norvegicus. To determine the most crucial developmental time of exposure to PCB in Sprague-Dawley rat pups, rat pups were exposed to PCB at differing weeks of either gestation period or the first postnatal week. Behavioral tests were performed for the different rat pups, as well as blood …

Go to article

First Prev Next Last