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The George-Anne Daily, Georgia Southern University Jan 2026

The George-Anne Daily, Georgia Southern University

George-Anne Media Group: Newsletters & Magazines

No abstract provided.


A Real-Time Mobile Robotic System For Crack Detection In Construction Using Two-Stage Deep Learning, Emmanuella Ogun, Yong Ann Voeurn, Doyun Lee Jan 2026

A Real-Time Mobile Robotic System For Crack Detection In Construction Using Two-Stage Deep Learning, Emmanuella Ogun, Yong Ann Voeurn, Doyun Lee

Civil Engineering & Construction: Faculty Publications

The deterioration of civil infrastructure poses a significant threat to public safety, yet conventional manual inspections remain subjective, labor-intensive, and constrained by accessibility. To address these challenges, this paper presents a real-time robotic inspection system that integrates deep learning perception and autonomous navigation. The proposed framework employs a two-stage neural network: a U-Net for initial segmentation followed by a Pix2Pix conditional generative adversarial network (GAN) that utilizes adversarial residual learning to refine boundary accuracy and suppress false positives. When deployed on an Unmanned Ground Vehicle (UGV) equipped with an RGB-D camera and LiDAR, this framework enables simultaneous automated crack detection …


Disparities In School Discipline For Middle And High Schools In Shelby County Schools And Surrounding Suburban Municipalities, Robert Arnold Jan 2026

Disparities In School Discipline For Middle And High Schools In Shelby County Schools And Surrounding Suburban Municipalities, Robert Arnold

Electronic Theses and Dissertations Archive

This study explores how the use of proactive and reactive discipline strategies, as contained in schools’ student handbooks and codes of conduct, are related to school and neighborhood characteristics. The neighborhood and school level characteristics consist of urbanicity, socioeconomic need, racial composition, attendance rates, suspension rates, and academic performance. The total sample consists of 93 middle and high schools in the Shelby County School District (the most populous urban district in Tennessee) and its surrounding suburban municipal districts of Bartlett, Millington, Collierville, Arlington, Lakeland and Germantown. The geospatial analysis and logistic regression analysis reveal that proactive discipline approaches and alternatives …


Understanding Higher-Order Motion Terms In Image Sequences, Fisseha Admasu Ferede Jan 2026

Understanding Higher-Order Motion Terms In Image Sequences, Fisseha Admasu Ferede

Electronic Theses and Dissertations Archive

This dissertation presents a comprehensive framework for learning accurate, and physically meaningful representation of motion from image sequences. The central theme of this work lies in advancing optical flow estimation from discrete-time two-frame formulation toward a continuous time multi-frame model capable of learning higher-order motion terms and dynamics, with wide ranging applications including developing structural disease biomarkers from medical images. We first develop SSTM (Spatiotemporal Recurrent Transformer for Multi-Frame Optical Flow Estimation), a deep learning model that leverages a sequence of multi-frames to infer accurate optical flow by learning temporal dependencies across successive motion cues. The architecture integrates recurrent 3D …


Cardozo Law Photograph Collection, Dr. Lillian & Dr. Rebecca Chutick Law Library Jan 2026

Cardozo Law Photograph Collection, Dr. Lillian & Dr. Rebecca Chutick Law Library

Finding Aids

The Benjamin N. Cardozo School of Law Photograph Collection documents the history of the law school through photographs of faculty, students, alumni, commencements, academic conferences, lectures, receptions, and other institutional events. The collection includes photographic prints, negatives, and related papers dating from the late 1970s through the 2010s, with the bulk of materials dating from the 1990s and 2000s. This finding aid provides a container-level inventory of the collection.

Extent: 4 linear feet (4 photograph boxes) and 2 oversize boxes (20 × 16 × 5 inches each).

Provenance: Compiled by former Cardozo Law administration and communications staff and subsequently transferred …


36th Annual Mlk Jr. Gospel Festival Returns To Bloomington-Normal, Jeffery Woodard Jan 2026

36th Annual Mlk Jr. Gospel Festival Returns To Bloomington-Normal, Jeffery Woodard

Press Releases 2020-2029

No abstract provided.


Perioperative Fluid Management In Pancreaticoduodenectomy In The Era Of Goal-Directed Fluid Therapy: A Review Of The Literature, Meghan D Grim, Richard Zheng, Nader Hanna, Harish Lavu, Charles J. Yeo, Avinoam Nevler Jan 2026

Perioperative Fluid Management In Pancreaticoduodenectomy In The Era Of Goal-Directed Fluid Therapy: A Review Of The Literature, Meghan D Grim, Richard Zheng, Nader Hanna, Harish Lavu, Charles J. Yeo, Avinoam Nevler

Department of Surgery Faculty Papers

BACKGROUND: Pancreaticoduodenectomy (PD) is the only curative option for localized pancreatic head and periampullary malignancies. However, PD is associated with significant perioperative morbidity. Perioperative fluid management has emerged as an important modifiable factor influencing surgical outcomes in PD.

METHODS: In this qualitative review, PubMed/Medline searches were performed between March and August 2025 to review the terms "pancreaticoduodenectomy," "fluid management," "Enhanced Recovery After Surgery," "complications," and related terms.

RESULTS: Historically, liberal fluid administration was favored to compensate for third-space losses, but contemporary evidence has linked excessive fluid volumes to complications, such as postoperative pancreatic fistula, anastomotic edema, and increased inflammatory responses. …


Pre-Operative Internal Maxillary Artery Embolization For Temporomandibular Joint Replacement: Safety And Outcomes From A 10-Year Institutional Experience, Guilherme Dabus Jan 2026

Pre-Operative Internal Maxillary Artery Embolization For Temporomandibular Joint Replacement: Safety And Outcomes From A 10-Year Institutional Experience, Guilherme Dabus

All Publications

Background: Temporomandibular joint replacement (TMJR) can result in large volume blood loss (BL) from the underlying internal maxillary artery (IMA). Pre-operative IMA embolization has been utilized to reduce intra-operative BL, but prior studies are limited to small case series.

Methods: Adult patients undergoing pre-operative IMA embolization for TMJR between June 2014 and September 2024 at a single institution were included. Electronic medical records were reviewed for demographic information, treatment details, and outcomes. Historical controls were identified via citations and PubMed searches.

Results: Pre-operative IMA embolization was performed in 73 patients (108 sides) undergoing TMJR. Coils were used in 96% of …


No More “Vague Handwaving”: Applying The Overlooked “Person Aggrieved” Provision Of The North Carolina Administrative Procedure Act To Election Litigation, William Allred Jan 2026

No More “Vague Handwaving”: Applying The Overlooked “Person Aggrieved” Provision Of The North Carolina Administrative Procedure Act To Election Litigation, William Allred

Duke Law Journal

The North Carolina Administrative Procedure Act requires claimants against state agencies to be “persons aggrieved,” meaning they have been “affected substantially” in their “person, property, or employment” by the challenged agency action. But in the 2024 general election, North Carolina state courts largely ignored this requirement, permitting plaintiffs to sue based on allegations of harm that some considered to reflect no more than “vague handwaving about election integrity.” This fact-light litigation strained state resources and reduced ballot access. But the solution is not so simple as just reminding courts that a statute exists. State appellate courts have never explained how …


Influence Of Co2 Curing On Carbonation Depth, Phase Composition, And Micro-Mechanical Properties Of Fbc Ash-Blended Cementitious Materials, Heejung Jun, Seongho Han, Sanghwon Wi, Jinyoung Yoon Jan 2026

Influence Of Co2 Curing On Carbonation Depth, Phase Composition, And Micro-Mechanical Properties Of Fbc Ash-Blended Cementitious Materials, Heejung Jun, Seongho Han, Sanghwon Wi, Jinyoung Yoon

Civil, Architectural and Environmental Engineering Faculty Research & Creative Works

This study investigates the physicochemical and mechanical performance of cementitious composites incorporating fluidized bed combustion (FBC) ash under accelerated carbon dioxide (CO2) curing. FBC ash, due to its high contents of free calcium oxide (CaO) and sulfate (SO3), has been reported to cause challenges, such as volume instability and lower early-age strength. To address these limitations, CO2 curing was applied to promote accelerated carbonation and stabilize the hydration products. Cement paste and mortar samples, made with up to 40 % by cement weight replacement with FBC ash (labelled CF), were subjected to either CO2 curing …


Insights On Global Rangeland Ecosystem Services Shaped By Grazing And Fertilization, Laura Yahdjian, Sofía Campana, Pedro M. Tognetti, Juan Alberti, Pamela Graff, Cecilia Molina, Elizabeth T. Borer, Eric W. Seabloom, Suzanne M. Prober, Andrew S. Macdougall, Anita C. Risch, Jodi N. Price, Sally A. Power, Isabel C. Barrio, Erika Hersch-Green, Philip A. Fay, Sumanta Bagchi, Jonathan D. Bakker, Dana Blumenthal, Elizabeth H. Boughton, Cynthia S. Brown, Miguel N. Bugalho, Marc Cadotte, Maria C. Caldeira, Jane A. Catford, Clinton Carbutt, Qingqing Chen, Scott L. Collins, Thomas W. Crowther, Carla D’Antonio, Christopher R. Dickman Jan 2026

Insights On Global Rangeland Ecosystem Services Shaped By Grazing And Fertilization, Laura Yahdjian, Sofía Campana, Pedro M. Tognetti, Juan Alberti, Pamela Graff, Cecilia Molina, Elizabeth T. Borer, Eric W. Seabloom, Suzanne M. Prober, Andrew S. Macdougall, Anita C. Risch, Jodi N. Price, Sally A. Power, Isabel C. Barrio, Erika Hersch-Green, Philip A. Fay, Sumanta Bagchi, Jonathan D. Bakker, Dana Blumenthal, Elizabeth H. Boughton, Cynthia S. Brown, Miguel N. Bugalho, Marc Cadotte, Maria C. Caldeira, Jane A. Catford, Clinton Carbutt, Qingqing Chen, Scott L. Collins, Thomas W. Crowther, Carla D’Antonio, Christopher R. Dickman

Michigan Tech Publications

Rangelands are crucial to human well-being, but their ability to provide ecosystem services is threatened. We (1) quantified key ecosystem services provided by rangelands, (2) assessed short- and long-term impacts of fertilization (nutrient addition) and the exclusion of large grazing herbivores with fences (herbivore exclusion) on services, and (3) identified synergies and trade-offs among services. We measured indicators of ecosystem services and plant diversity at 79 sites across six continents in the global Nutrient Network. Short-term herbivore exclusion increased forage quantity and soil fertility, but longer-term herbivore exclusion decreased both along with plant richness and pollination. Nutrient addition improved forage …


Prevalence Of And Factors Associated With Nurse Burnout In The Us, Megha K. Shah, Nikhila Gandrakota, Jeannie P. Cimiotti, Neena Ghose, Miranda Moore, Mohammed K. Ali Jan 2026

Prevalence Of And Factors Associated With Nurse Burnout In The Us, Megha K. Shah, Nikhila Gandrakota, Jeannie P. Cimiotti, Neena Ghose, Miranda Moore, Mohammed K. Ali

Individual Open Access Articles

IMPORTANCE Clinician burnout is a major risk to the health of the US. Nurses make up most of the health care workforce, and estimating nursing burnout and associated factors is vital for addressing the causes of burnout.

OBJECTIVE To measure rates of nurse burnout and examine factors associated with leaving or considering leaving employment owing to burnout. DESIGN,

SETTING, AND PARTICIPANTS This secondary analysis used cross-sectional survey data collected from April 30 to October 12, 2018, in the National Sample Survey of Registered Nurses in the US. All nurses who responded were included (N = 50 273). Data were analyzed …


Ai-Assisted Tailored Intervention For Nurse Burnout: A Three-Group Randomized Controlled Trial, Gumhee Baek, Chiyoung Cha Jan 2026

Ai-Assisted Tailored Intervention For Nurse Burnout: A Three-Group Randomized Controlled Trial, Gumhee Baek, Chiyoung Cha

Individual Open Access Articles

Background: High-stress environments, heavy workloads, and the emotional demands of patient care, which are common challenges faced by nurses, are factors that can lead to burnout. Shift work can make traditional burnout interventions costly and difficult to implement. Artificial intelligence (AI) could offer solutions that are less constrained by time, resources, and labor.

Aim: To investigate the effectiveness of an AI-assisted intervention in reducing nurse burnout.

Methods: A single-blind, three-group, randomized controlled trial of 120 nurses (40 per group) was conducted from June 2023 to July 2023. The AI-assisted tailored intervention included two 2-week programs, delivering one of four programs …


Costs And Cost-Effectiveness Of Improved Nurse Staffing Levels And Skill Mix In Acute Hospitals: A Systematic Review, Peter Griffiths, Christina Saville, Jane Ball, Chiara Dall'ora, Paul Meredith, Lesley Turner, Jeremy Jones Jan 2026

Costs And Cost-Effectiveness Of Improved Nurse Staffing Levels And Skill Mix In Acute Hospitals: A Systematic Review, Peter Griffiths, Christina Saville, Jane Ball, Chiara Dall'ora, Paul Meredith, Lesley Turner, Jeremy Jones

Individual Open Access Articles

Increasing registered nurse staffing and skill mix can be a net cost-saving solution to nurse shortages. Contrary to the strong policy push towards a dilution of nursing skill mix, investment in supply of RNs should become the priority.


Mediating Role Of Lifestyle Factors In The Resilience–Job Satisfaction Relationship Among Nurses: A Descriptive Correlational Study, Lena I. Serafin, Katarzyna Wesołowska-Gorniak, Angeli Malewska, Karolina Kruszewska, Justyna Kujawa, Bozena Czarkowska-Pączek Jan 2026

Mediating Role Of Lifestyle Factors In The Resilience–Job Satisfaction Relationship Among Nurses: A Descriptive Correlational Study, Lena I. Serafin, Katarzyna Wesołowska-Gorniak, Angeli Malewska, Karolina Kruszewska, Justyna Kujawa, Bozena Czarkowska-Pączek

Individual Open Access Articles

Given the global nursing shortage and the increasing prevalence of workplace stressors, resilience has emerged as a crucial factor influencing job satisfaction, preventing burnout, and ensuring high-quality patient care. While previous research has established a connection between resilience and various occupational outcomes, the mediating effect of health-promoting behaviors—such as physical activity, diet, and sleep—remains largely unexplored, underscoring the need for further investigation in this area. Therefore, the objective of this study is to examine the effect of chosen lifestyle aspects on the connection between resilience and job satisfaction among nurses.


Personal And Work-Related Factors Associated With Nurse Resilience: An Updated Systematic Review Using Meta-Analysis And Narrative Synthesis, Fiona Yu, Deborah Raphael, Lisa Mackay, Melody Smith, Ritin Fernandez Jan 2026

Personal And Work-Related Factors Associated With Nurse Resilience: An Updated Systematic Review Using Meta-Analysis And Narrative Synthesis, Fiona Yu, Deborah Raphael, Lisa Mackay, Melody Smith, Ritin Fernandez

Individual Open Access Articles

Background: Nursing shortages and increased workforce turnover have significantly increased nurses’ workloads, thus increasing the risk of burnout and stress, particularly during the COVID-19 pandemic. A systematic review published in 2019 suggested that resilience could act as a buffer to adversity; however, the factors associated with resilience during and after this global pandemic have not been identified.

Objectives: To identify personal and work-related factors associated with nurse resilience, including the period during and after the COVID-19 pandemic.

Design: Systematic review.

Data Sources: The search was conducted between January and February 2024 in the following databases: CINAHL Plus, MEDLINE (Ovid), PsycINFO, …


Advanced Practice Registered Nurse Burnout In Magnet Hospitals: Opportunities For Organizational Intervention, Lori Kennedy, Heather Brom, Karen B. Lasater, Nancy M. Albert, Barbara Holmes Gobel, Christi Delemos, Lisa M. Williams, Linda H. Williams, Linda H. Aiken Jan 2026

Advanced Practice Registered Nurse Burnout In Magnet Hospitals: Opportunities For Organizational Intervention, Lori Kennedy, Heather Brom, Karen B. Lasater, Nancy M. Albert, Barbara Holmes Gobel, Christi Delemos, Lisa M. Williams, Linda H. Williams, Linda H. Aiken

Individual Open Access Articles

OBJECTIVE: To determine modifiable organizational factors associated with advanced practice RN (APRN) burnout in Magnet®-designated hospitals to guide organizational interventions to improve APRN well-being and retention.

METHODS: Cross-sectional study of work environments of 50 US Magnet hospitals and the associated well-being of 21 855 of their clinicians (APRNs, physician assistants, physicians [MDs], RNs).

RESULTS: Overall, 37%of APRNs experienced high burnout compared with 34% of MDs (P < 0.05) and 49% of RNs (P < 0.001); additionally, 32%of APRNs intended to leave their jobs. APRN burnout was significantly lower in organizations that minimized chaotic working conditions, provided APRNs more control over their workloads, involved APRNs in shared governance, improved clinician and management relations, and improved interprofessional teamwork.

CONCLUSIONS:Well-being and retention of APRNs in Magnet hospitals require their greater engagement in organization processes and systems that improve work environments.


Evidence-Based Practice Improves Patient Outcomes And Healthcare System Return On Investment: Findings From A Scoping Review, Linda Connor, Jennifer Dean, Molly Mcnett, Donna M. Tydings, Amanda Shrout, Penelope F. Gorsuch, Ashley Hole, Laura Moore, Roy Brown, Bernadette Mazurek Melnyk, Lynn Gallagher-Ford Jan 2026

Evidence-Based Practice Improves Patient Outcomes And Healthcare System Return On Investment: Findings From A Scoping Review, Linda Connor, Jennifer Dean, Molly Mcnett, Donna M. Tydings, Amanda Shrout, Penelope F. Gorsuch, Ashley Hole, Laura Moore, Roy Brown, Bernadette Mazurek Melnyk, Lynn Gallagher-Ford

Individual Open Access Articles

Background: Evidence-based practice and decision-making have been consistently linked to improved quality of care, patient safety, and many positive clinical outcomes in isolated reports throughout the literature. However, a comprehensive summary and review of the extent and type of evidence-based practices (EBPs) and their associated outcomes across clinical settings are lacking.

Aims: The purpose of this scoping review was to provide a thorough summary of published literature on the implementation of EBPs on patient outcomes in healthcare settings.

Methods: A comprehensive librarian-assisted search was done with three databases, and two reviewers independently performed title/abstract and full-text reviews within a systematic …


Simultaneous Determination Of Dendrobine And Four Bibenzyl Compounds In Dendrobium By Uplc-Ms/Ms, Li Zhanbin, Lu Yang, Tao Guangcan, Wu Yang, Ma Kai Jan 2026

Simultaneous Determination Of Dendrobine And Four Bibenzyl Compounds In Dendrobium By Uplc-Ms/Ms, Li Zhanbin, Lu Yang, Tao Guangcan, Wu Yang, Ma Kai

Food and Machinery

[Objective] To develop a method for determining the contents of dendrobine, dendrophenol, moscatilin, chrysotoxine, and erianin in dendrobium by ultra performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). [Methods] The samples were ultrasonically extracted with 70% methanol (by volume) for 40 min. The extract was filtered through a 0.22 μm organic membrane and then determined by UPLC-MS/MS.Gradient elution was performed using methanol and 0.1% formic acid water as the mobile phase. The determination was carried out in MRM mode with an electrospray ionization (ESI) source in positive ion mode, and quantification was done by the external standard method. [Results] Dendrobine, dendrophenol, chrysotoxine, …


Deliver Us From Evil., Ethan Schimmoeller Jan 2026

Deliver Us From Evil., Ethan Schimmoeller

Ambulatory and Primary Care Articles

No abstract provided.


Direct Effects Of Capsaicin On Voltage-Dependent Calcium Channels Of Mammalian Skeletal Muscle, Dmytro Isaev, Tatiana Prytkova, Badarunnisa Mohamed, Mohamed Omar Mahgoub, Keun Hang Susan Yang, Murat Oz Jan 2026

Direct Effects Of Capsaicin On Voltage-Dependent Calcium Channels Of Mammalian Skeletal Muscle, Dmytro Isaev, Tatiana Prytkova, Badarunnisa Mohamed, Mohamed Omar Mahgoub, Keun Hang Susan Yang, Murat Oz

All Works

Capsaicin, a naturally occurring polyphenol, is known to affect energy expenditure and muscle fatigue and modulate contractions in skeletal muscle. The L-type Ca2+ channels are known to be an important ion channel involved in the various muscle functions and the effect of capsaicin on the skeletal L-type Ca2+ channels is currently unknown. In this study, the effects of capsaicin and capsaicin analogs on depolarization-induced Ca2+ effluxes through L-type Ca2+ channels in transverse tubule membranes from rabbit skeletal muscle and L-type Ca2+ currents recorded using the whole-cell patch clamp technique in rat myotubes were examined. Capsaicin, …


Sullivan County Advisory Council January 2026 Meeting Minutes, Extension Jan 2026

Sullivan County Advisory Council January 2026 Meeting Minutes, Extension

Advisory Council

No abstract provided.


Uab Jazz Summit Will Give Young Musicians Unique Opportunities Feb. 6, Shannon Thomason Jan 2026

Uab Jazz Summit Will Give Young Musicians Unique Opportunities Feb. 6, Shannon Thomason

Browse All News

No abstract provided.


Trip Generation Model For Mixed-Use Development In Klang Valley, Malaysia., Goh Boon Hoe Jan 2026

Trip Generation Model For Mixed-Use Development In Klang Valley, Malaysia., Goh Boon Hoe

Student Works (2020-2029)

Mixed-Use Developments (MXDs) are single development projects that integrate and interact with different land uses, such as offices, retail, restaurants, entertainment venues, hotels, and/or residential areas. MXDs are internally connected, allowing users of different land uses to share internal streets, walkways, driveways, and parking spaces. Traffic is estimated to be reduced with such developments. Currently, in Malaysia, there is no standard procedure to estimate the MXD trip generation rates. The Malaysian Trip Generation Manual (MTGM) 2010 is the guideline used to forecast future trips for a single land use and hence, by summing the trip generation rates for multiple land …


New Comorbidity Index Associated With Survival After Chimeric Antigen Receptor T-Cell Therapy For Large B-Cell Lymphoma, Uri Greenbaum, Amanda Cashen, Et Al. Jan 2026

New Comorbidity Index Associated With Survival After Chimeric Antigen Receptor T-Cell Therapy For Large B-Cell Lymphoma, Uri Greenbaum, Amanda Cashen, Et Al.

2020-Current year OA Pubs

No abstract provided.


Decoupling Of Reproduction And Lifespan Trade-Off In Caenorhabditis Elegans Through Microbial Programming, Nora M. Villafuerte Jan 2026

Decoupling Of Reproduction And Lifespan Trade-Off In Caenorhabditis Elegans Through Microbial Programming, Nora M. Villafuerte

LSU Master's Theses

The microbiome is increasingly recognized as a major regulator of host physiology. Using the Caenorhabditis elegans model, we investigated how natural commensal bacteria modulate host reproduction and lifespan through internal egg hatching, a phenotype in which retained embryos hatch within the maternal body. Screening strains from the CeMbio collection identified four focal strains Ochrobactrum BH3, Lelliottia JUb66, Pantoea BIGb0393, and Enterobacter CEent1 that significantly increased internal egg hatching during the late reproductive period. This contrasts with pathogenic bacteria, which induce early-onset internal egg hatching. Across the focal strains, worms exhibited reduced total brood size but an expanded reproductive window relative …


Evaluation Of 14 Round Tomato Cultivars In Southwest Michigan In 2025, Ben Phillips Jan 2026

Evaluation Of 14 Round Tomato Cultivars In Southwest Michigan In 2025, Ben Phillips

Midwest Vegetable Trial Reports

A round tomato cultivar trial was planted at the Southwest Michigan Research and Extension Center (42.081985, -86.354087, Benton Harbor, Michigan). Bejo (BJ), Enza Zaden (EZ), North Carolina State University (NCSU), PanAmerican (PA), and Sakata (SK) seed companies donated 14 cultivars for plastic mulch-bedded hand harvest. Overall, the trial quality was good, with periods of high heat slowing ripening.


Evaluation Of Eight Parthenocarpic Slicing Cucumber Cultivars And Four Production Systems In Southwest Michigan In 2025, Ben Phillips Jan 2026

Evaluation Of Eight Parthenocarpic Slicing Cucumber Cultivars And Four Production Systems In Southwest Michigan In 2025, Ben Phillips

Midwest Vegetable Trial Reports

In the machine-harvested pickling cucumber system, parthenocarpic (parth) varieties make up about 50% of the market, and is growing. The seed cost is higher, but this is offset by not needing to contract or truck bees and an increased yield when planted at half the population of standard varieties. Additionally, they hold their shape and size better when moisture and temperatures fluctuate, reducing docked payments from graders. In pickling cucumbers, a breakeven yield is approximately 250 bushels per acre with a plant population of 30,000 plants per acre. Plant populations can play a strong role in economic viability, as demonstrated …


Therapeutic Responses In Patients With Advanced Nsclc Enrolled In Early-Phase Clinical Trials At Md Anderson, Jeong Uk Lim, Heather Y Lin, Lei Kang, Hung Le, Tin-Yun Tang, Ecaterina Elena Dumbrava, Aung Naing, Sarina A Piha-Paul, Jordi Rodon Ahnert, Apostolia Maria Tsimberidou, Timothy A Yap, Siqing Fu, Funda Meric-Bernstam, David S Hong Jan 2026

Therapeutic Responses In Patients With Advanced Nsclc Enrolled In Early-Phase Clinical Trials At Md Anderson, Jeong Uk Lim, Heather Y Lin, Lei Kang, Hung Le, Tin-Yun Tang, Ecaterina Elena Dumbrava, Aung Naing, Sarina A Piha-Paul, Jordi Rodon Ahnert, Apostolia Maria Tsimberidou, Timothy A Yap, Siqing Fu, Funda Meric-Bernstam, David S Hong

Faculty, Staff and Student Publications

We evaluated clinical outcomes and safety profiles in patients with non-small cell lung cancer (NSCLC) treated in early-phase trials. A retrospective review of 546 NSCLC cases treated from January 2016 to December 2024 at The University of Texas MD Anderson Cancer Center was performed using the MD Anderson CHIMERA database. Patients were categorized into seven groups based on treatment regimen. The overall objective response rate (ORR) was 19.9%, and the highest ORRs were in the targeted combination (30.8%) and targeted monotherapy (29.7%) groups. Gene alteration–matched therapy, serum albumin level, metastatic burden, treatment group, and liver metastasis were independently associated with …


Genome-Wide Gene By Sleepiness Interaction Analysis For Sleep Apnea, Pavithra Nagarajan, Nuzulul Kurniansyah, Jiwon Lee, Sina A Gharib, Yushan Xu, Brian Spitzer, Hufeng Zhou, Eric Boerwinkle, Han Chen, Daniel J Gottlieb, Xiuqing Guo, Nancy L Heard-Costa, Bertha A Hidalgo, Daniel Levy, Peter Y Liu, Hao Mei, Rebecca Montalvan, Sutapa Mukherjee, Kari E North, George T O'Connor, Lyle J Palmer, Sanjay R Patel, Bruce M Psaty, Shaun M Purcell, Laura M Raffield, Stephen S Rich, Jerome I Rotter, Richa Saxena, Albert V Smith, Katie L Stone, Xiaofeng Zhu, Topmed Sleep Trait Working Group, Brian E Cade, Tamar Sofer, Susan Redline, Heming Wang Jan 2026

Genome-Wide Gene By Sleepiness Interaction Analysis For Sleep Apnea, Pavithra Nagarajan, Nuzulul Kurniansyah, Jiwon Lee, Sina A Gharib, Yushan Xu, Brian Spitzer, Hufeng Zhou, Eric Boerwinkle, Han Chen, Daniel J Gottlieb, Xiuqing Guo, Nancy L Heard-Costa, Bertha A Hidalgo, Daniel Levy, Peter Y Liu, Hao Mei, Rebecca Montalvan, Sutapa Mukherjee, Kari E North, George T O'Connor, Lyle J Palmer, Sanjay R Patel, Bruce M Psaty, Shaun M Purcell, Laura M Raffield, Stephen S Rich, Jerome I Rotter, Richa Saxena, Albert V Smith, Katie L Stone, Xiaofeng Zhu, Topmed Sleep Trait Working Group, Brian E Cade, Tamar Sofer, Susan Redline, Heming Wang

Faculty, Staff and Student Publications

Study objectives: Excessive daytime sleepiness (EDS), influenced by environmental and social-behavioral factors, is reported by a subset of patients with sleep apnea-a group that may be at elevated cardiovascular risk. However, it is unclear whether sleep apnea with and without EDS have distinct genetic underpinnings. In this study, we perform gene-by-EDS interaction analyses for apnea hypopnea index, a diagnostic marker of sleep apnea severity, to understand EDS's influence on its underlying genetic risk.

Methods: Discovery interaction analyses for common variants and gene-based rare variants were conducted respectively using multi-ethnic Trans-Omics for Precision Medicine (N = 11 619) data, followed by …