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Overview Of The Ergonomic Model Of Soccer And The Training Process, James J. Collins, Shane Malone, Kieran Collins Jan 2026

Overview Of The Ergonomic Model Of Soccer And The Training Process, James J. Collins, Shane Malone, Kieran Collins

Research Outputs: 2025-Present

Soccer is a complex sport with significant physical, physiological, psychological, technical, and tactical demands on players. This review presents an ergonomics-based model of soccer performance, emphasizing that no single component operates in isolation. Building on the foundational ergonomic framework, this review integrates contemporary evidence on training load monitoring, ecological dynamics, and cognitive-perceptual performance dimensions not systematically addressed in prior frameworks. Elite outfield players cover 9–14 km·h−1 per match, with high-speed running (19.8–24.8 km·h−1) making up about 20% of total distance and sprinting (>25 km·h−1) around 2%. These outputs vary by playing position, tactical formation, …


Exploring The Prevalence Of Eating Disorders, Low Sex Drive, And Exercise Compulsion Among Professional And Non-Professional Elite Male Rugby Union Players, Gary Sweeney, Siobhain Mcardle, Danielle Logue, Nessan Costello, Kieran Collins Jan 2026

Exploring The Prevalence Of Eating Disorders, Low Sex Drive, And Exercise Compulsion Among Professional And Non-Professional Elite Male Rugby Union Players, Gary Sweeney, Siobhain Mcardle, Danielle Logue, Nessan Costello, Kieran Collins

Research Outputs: 2025-Present

Rugby union exhibits large variations in the idealised player physical profiles across positions. The pursuit of physique ideals with limited professional support can influence eating disorder symptomology, exercise compulsion, and low sexual drive. The primary aims were to (1) explore the prevalence of elite male rugby union players who are at risk for eating disorders, low sex drive, and exercise compulsion, and (2) explore the relationship between risk and players’ professional status, weight, age, and playing position. A secondary aim was to explore the nutritional service support and dietary monitoring practices experienced by the players. Participants were recruited from four …


Am I Top Of The Pops? Does Feedback Of Live Gps Between Sets Of Hurling-Specific Small-Sided Games Improve Subsequent Running And Physiological Performance?, Shane Malone, John Keane, Tom Hargroves, Conor P. Clancy, John David Duggan, Damien Young, Kieran Collins Jan 2026

Am I Top Of The Pops? Does Feedback Of Live Gps Between Sets Of Hurling-Specific Small-Sided Games Improve Subsequent Running And Physiological Performance?, Shane Malone, John Keane, Tom Hargroves, Conor P. Clancy, John David Duggan, Damien Young, Kieran Collins

Research Outputs: 2025-Present

The investigation aimed to determine if live feedback of team- and player-specific global positioning system (GPS) running performance data between bouts of hurling small-sided games (SSGs) altered the physical and physiological responses during subsequent bouts of SSGs during a 6-week hurling pre-season period. Twenty-four (n = 24) hurling players (age 25.5 ± 3.2 years; height 177.9 ± 3.2 cm; body mass 83.5 ± 4.5 kg) received either feedback or no feedback during hurling-specific SSGs across a 6-week pre-season period. Teams were assigned to two specific groups, a) GPS live feedback or b) no GPS live feedback (control) for each session, …


Efficacious Anti-Cancer Drugs Targeting Nicotinamide N-Methyltransferase (Nnmt) In Cultured Human Oral Squamous Cell Carcinoma (Oscc), Brian Maloney, Martyna Kubisztal, Ziqian Ge, Yin Lu, Lisa Strotmann, Adrianna Budziňska, Mary F. Rooney, Marilena Karavyraki, Andrew Knox, Richard K. Porter Jan 2026

Efficacious Anti-Cancer Drugs Targeting Nicotinamide N-Methyltransferase (Nnmt) In Cultured Human Oral Squamous Cell Carcinoma (Oscc), Brian Maloney, Martyna Kubisztal, Ziqian Ge, Yin Lu, Lisa Strotmann, Adrianna Budziňska, Mary F. Rooney, Marilena Karavyraki, Andrew Knox, Richard K. Porter

Research Outputs: 2025-Present

Background/Objectives: Oral squamous cell carcinoma (OSCC) is a major cause of human cancer. The enzyme, nicotinamide N-methyltransferase (NNMT), is overexpressed in a variety of human cancers, including OSCC. Our objective was to target NNMT with novel inhibitors and determine their anti-cancer efficacy while shedding light on their possible mechanism of action. Methods: We identified two small molecule inhibitors of NNMT (AG-670 and AO-022) based on a pharmacophore of the in silico nicotinamide binding site. These inhibitors were investigated for (i) potency to inhibit the activity of the isolated NNMT enzyme (EC50 values), (ii) cytotoxicity (IC50 values) against the …


Physique Development And Management Shape Experiences Of Low Energy Availability Risk In Elite Professional Male Rugby Union Players, Gary Sweeney, Siobhain Mcardle, Nessan Costello, Kieran Collins Jan 2026

Physique Development And Management Shape Experiences Of Low Energy Availability Risk In Elite Professional Male Rugby Union Players, Gary Sweeney, Siobhain Mcardle, Nessan Costello, Kieran Collins

Research Outputs: 2025-Present

This study aimed to explore elite male rugby union players’ perceptions and lived experiences of physique development and management in relation to low energy availability risk. Semi-structured interviews (29 ± 8 min) were conducted with 18 players (senior: n = 9; academy: n = 9; mean age: 23 ± 3) across four professional rugby union clubs in Ireland. Through reflexive thematic analysis, the following themes were constructed. Players had limited awareness of low energy availability, yet described experiences consistent with symptoms, including fatigue, low mood and reduced libido. A pervasive physique culture, characterised by body composition ‘ideals’ and weight or …


From Platelets To Particles: Optimizing Extracellular Vesicle Isolation In A National Blood Centre, Y. Chintala, A. Waters, F. Mcgrath, A. Lorusso, C. Wynne, S. Meaney Jan 2026

From Platelets To Particles: Optimizing Extracellular Vesicle Isolation In A National Blood Centre, Y. Chintala, A. Waters, F. Mcgrath, A. Lorusso, C. Wynne, S. Meaney

Research Outputs: 2025-Present

Background and Objectives: Platelet-derived extracellular vesicles (PEVs) are submicron, membrane-bound particles released upon platelet activation, with a recognized role in haemostasis, inflammation and immunoregulation. PEVs remain insufficiently characterized in blood products. This study compared four isolation methods to evaluate their impact on PEV yield, purity and characteristics, aiming to identify a practical approach for transfusion service workflows. Materials and Methods: PEVs were isolated from expired single-donor aphaeresis platelet concentrates (n = 12) using methods based on different isolation principles: ultracentrifugation (UC), size exclusion chromatography (SEC), mixed size/charge separation (hybrid) and an affinity-based spin column method (affinity). Size, number and biochemical …


Order Of The Coif Program, August 14, 2026, University Of South Carolina School Of Law Order Of The Coif Jan 2026

Order Of The Coif Program, August 14, 2026, University Of South Carolina School Of Law Order Of The Coif

Order of the Coif Programs and Documents

No abstract provided.


Determining Knowledge Gaps In Natural Disaster Preparedness: An Exploratory Analysis Of Socioeconomic Variables And Response Quality, Michelle S. Repass Jan 2026

Determining Knowledge Gaps In Natural Disaster Preparedness: An Exploratory Analysis Of Socioeconomic Variables And Response Quality, Michelle S. Repass

Theses and Dissertations

This exploratory study examines potential knowledge gaps in natural disaster preparedness across socioeconomic groups in Lee County, Alabama and identifies communication barriers affecting response behavior through the lens of the knowledge gap hypothesis. Survey data from 20 residents were analyzed using an objective socioeconomic status (OSES) score based on household income and highest level of education. Results indicate that while most respondents reported access to weather alerts and favorable behavioral responses that align with current guidelines from the National Weather Service, gaps are present in comprehension, response timing, and engagement in risky behavior that could delay protective action. Findings suggest …


Practicing Contemporary Documentation: An Analysis Of Historic Influences And Personal Inspirations, Zoee D. Rasso Jan 2026

Practicing Contemporary Documentation: An Analysis Of Historic Influences And Personal Inspirations, Zoee D. Rasso

Theses and Dissertations

For my Honors Thesis, I proposed and created a solo exhibition of my artwork, researching the inspiration behind this work to determine its place within in the context of contemporary art history. My work as an artist centers on stylized, psychologically charged portraits of birds. Looking at art history, birds as artistic subjects are historically rooted in documentation, from scientific illustrations and game paintings to ukiyo-e. Analyzing my own creative influences such as James Audubon, Walton Ford, and Safet Zec, this Thesis explores my artistic background and influences, examining how I have developed as an artist over my tenure at …


Representation In Black Media And How It Affects Generational Mental Health, Amiya Smith Jan 2026

Representation In Black Media And How It Affects Generational Mental Health, Amiya Smith

Theses and Dissertations

This article examines how negative media portrayals of Black Americans have harmed their mental health. It traces the impact of persistent stereotypes and the lack of recognition for Black achievements in the media. Each chapter explores how media—from social media to movies—reinforces outdated stereotypes originating in the antebellum era and discusses how Black Americans have challenged these narratives to assert their identity. The article also highlights positive shifts in representation within the media industry, as well as research on how racial discrimination and media depictions influence the mental health and self-esteem of Black adolescents.


Exploring Secondary Stem Teachers’ Experiences In Online Learning Environments: A Directed Content Analysis Using The Community Of Inquiry Framework, Tiffany Janese Lester Jan 2026

Exploring Secondary Stem Teachers’ Experiences In Online Learning Environments: A Directed Content Analysis Using The Community Of Inquiry Framework, Tiffany Janese Lester

Theses and Dissertations

This study is a directed qualitative content analysis of 21 peer-reviewed studies published between 2020 and May 2025 on secondary STEM teaching in online environments. Using the Community of Inquiry framework, I examined how teaching, social, and cognitive presence shaped instructional strategies, teacher experiences, and reported challenges. Coding with deductive and inductive methods identified recurring themes: teachers adapted to digital platforms, navigated uneven levels of digital fluency, and implemented intentional strategies to maintain social interaction. The studies also revealed persistent equity gaps in access and participation alongside innovative approaches to course and pedagogical design. These themes demonstrate how secondary STEM …


Album Production: A Pedagogical Tool In Collegiate Brass Performance, Alex Doolittle Jan 2026

Album Production: A Pedagogical Tool In Collegiate Brass Performance, Alex Doolittle

Theses and Dissertations

This graduate research project investigates the value of musical album production within collegiate brass performance training and pedagogy. Within the collegiate sphere, brass pedagogy has long centered on live performance, such as juries, recitals, and ensemble participation as a primary performance tool; however, the 21st-century musical landscape is deeply rooted in technological and digital artistic dissemination. This study is used to push the boundaries of how technology can be interpreted in brass pedagogy by asking: How does album production function as a pedagogical tool in collegiate brass performance training?

In this project, I used an auto-ethnographic case study design, serving …


Literacy Intervention At The Middle Level: A Mixed-Methods Examination Of The Implementation Of Thinking Maps, Ashley Chantal Choice Jan 2026

Literacy Intervention At The Middle Level: A Mixed-Methods Examination Of The Implementation Of Thinking Maps, Ashley Chantal Choice

Theses and Dissertations

This study examined the implementation of Thinking Maps® as a literacy instructional intervention for students in grades four and five. Using an explanatory sequential mixed-methods design, the study investigated the effect of Thinking Maps® on student achievement, changes in students’ literacy-related work products, and teachers’ perceptions of the strategy. The study was conducted at a rural Title I elementary school in the southeastern United States and included nine teachers and 150 students across English language arts, mathematics, science, and social studies during an eight-week intervention period. Quantitative data included unit pretest and posttest scores from standards-aligned assessments and teacher perception …


Writing Against The War Machine: Wiflred Owen's Poetic Challenge To World War I Pro-War Rhetoric, Elizabeth Woods Jan 2026

Writing Against The War Machine: Wiflred Owen's Poetic Challenge To World War I Pro-War Rhetoric, Elizabeth Woods

Theses and Dissertations

Wilfred Owen, a soldier-poet who fought in World War I, is often labeled an anti-war poet, with some claiming that he was against the war in its entirety. This thesis explores the opinion that Owen is not an anti-war poet but rather that he wrote against anti-pro-war rhetoric. This includes all types of pro-war rhetoric influential in England for recruitment purposes but mainly focuses on poetry that would be published in newspapers for everyday readers to see. Owen seems to specifically resist two types of pro-war rhetoric, the myth of the German barbarian and what he called the old lie. …


Evaluating Hybrid Quantum-Classical Models For Image Classification In The Nisq Era, Utku Binkanat Jan 2026

Evaluating Hybrid Quantum-Classical Models For Image Classification In The Nisq Era, Utku Binkanat

Theses and Dissertations

This thesis presents a systematic empirical evaluation of quantum machine learning performance under noisy intermediate-scale quantum (NISQ) era constraints. Through 670 controlled experiments, it evaluated quantum kernel support vector machines and variational quantum classifiers against classical baselines on MNIST binary and multiclass classification tasks with systematic variation of problem difficulty, feature dimensionality (4, 8 qubits), and training set size (n ∈{100, 250, 400, 500, 2000, 4000}). Statistical rigor was ensured through five random seeds per condition and comprehensive significance testing. During the testing with binary datasets, classical methods (SVM, logistic regression, k-NN, neural networks) achieved 85.9% to 99.6% accuracy with …


Reframing Sexual Assault And Intimate Partner Violence Through A Maternal And Child Health Lens: Implications For Integrated Prevention, Policy, And Practice, Daija C. Gibson Jan 2026

Reframing Sexual Assault And Intimate Partner Violence Through A Maternal And Child Health Lens: Implications For Integrated Prevention, Policy, And Practice, Daija C. Gibson

Theses and Dissertations

Sexual assault and intimate partner violence remain persistent public health concerns in the United States, with significant consequences for individual health, family stability, and population well-being. Although these forms of violence are frequently addressed through criminal justice and behavioral health frameworks, less attention has been given to their implications within maternal and child health, where relational dynamics, life course development, and intergenerational outcomes are central. This study reframed SA and IPV as core MCH issues to examine how integrated, systems-based approaches can strengthen prevention efforts. A structured literature review and systematic synthesis of peer-reviewed studies published between 2015 and 2026 …


Timbral Effects Of 3d Printing Brass Wind Musical Instruments: A Comparison Between Traditional And 3d Printed Construction, Cole K. Zelman Jan 2026

Timbral Effects Of 3d Printing Brass Wind Musical Instruments: A Comparison Between Traditional And 3d Printed Construction, Cole K. Zelman

Theses and Dissertations

This study explores the timbral effects that manufacturing wind instruments from thermoplastics (via 3D printing) has in comparison to traditionally made instruments. The project mainly focuses on the individual properties of different thermoplastics in comparison to traditional materials like brass. The instrument tested is a C bugle for a simple example of a brass wind instrument and is compared directly against the traditional brass construction. Results employ spectral centroid, spectrograms, and professional subjective analysis to compare the different thermoplastic test samples to the control brass bugle.


Confidence In Action: A Qualitative Inquiry Into Teachers' Perceived Abilities In Implementing Instructional Technology, Latorri West Jan 2026

Confidence In Action: A Qualitative Inquiry Into Teachers' Perceived Abilities In Implementing Instructional Technology, Latorri West

Theses and Dissertations

Education is evolving through the integration of academic content and technology to support student success. Despite significant investments in educational technology, challenges persist in effective implementation, particularly in rural contexts where resources and support may be limited. Using the Technological Pedagogical Content Knowledge (TPACK) framework, the researcher investigated teachers’ perceptions of implementing the i-Ready adaptive learning platform in a rural Georgia school district. i-Ready, an adaptive diagnostic and instructional tool for reading and mathematics used by more than 25% of U.S. schools, represents a widely adopted educational technology that requires specific technical, pedagogical, and content knowledge for successful implementation.

The …


Analysis Of Risk Factors And Current Programs For Addressing Injuries In Children And Adolescents, Jahfel Nial Jones Iii Jan 2026

Analysis Of Risk Factors And Current Programs For Addressing Injuries In Children And Adolescents, Jahfel Nial Jones Iii

Theses and Dissertations

Unintentional injuries are a leading cause of morbidity and mortality among children and adolescents in the United States. These injuries result from various causes, including motor vehicle crashes, falls, suffocation, and poisoning. This capstone project examines the prevalence, risk factors, and prevention strategies for unintentional injuries among infants, children, and adolescents. Using a public health approach, this research explores evidence-based interventions and community-based programs that effectively reduce injury-related mortality. The project also incorporates data and insights from the Safe Kids Columbus program at Piedmont Columbus Regional, where various injury prevention initiatives have been implemented.

Findings revealed that motor vehicle crashes …


An Analysis Of Factors At A Private Liberal Arts College That Affect Student-Athlete Sense Of Belonging, Tamija Shrell Tucker Jan 2026

An Analysis Of Factors At A Private Liberal Arts College That Affect Student-Athlete Sense Of Belonging, Tamija Shrell Tucker

Theses and Dissertations

This study examined the factors affecting student-athletes sense of belonging at a private liberal arts college using Strayhorn’s Sense of Belonging Framework. The research used a mixed method approach and combined quantitative survey data from 112 undergraduate students with qualitative interviews from seven faculty members to analyze variations in academic readiness, institutional support and a sense of belonging. Despite that fact that non-athletes reported being significantly more academically prepared, quantitative data indicated that there was no statically significant difference in the overall sense of belonging between student-athletes and non-athletes. There was also a negative correlation between a sense of belonging …


Helping Nurses To ‘Get Their Good Work Out There’, Lori Grischott Msn, Rn, Nea-Bc, Npd-Bc, Rnc-Ob, Lauren Souchak Msn, Rn, Bea-Bc Jan 2026

Helping Nurses To ‘Get Their Good Work Out There’, Lori Grischott Msn, Rn, Nea-Bc, Npd-Bc, Rnc-Ob, Lauren Souchak Msn, Rn, Bea-Bc

Patient Care Services / Nursing

No abstract provided.


From Coverage To Care: Evaluating The Effects Of Aca Medicaid Expansion On Birth Outcomes, Bailey R. Lengfelder Jan 2026

From Coverage To Care: Evaluating The Effects Of Aca Medicaid Expansion On Birth Outcomes, Bailey R. Lengfelder

Economics Honors Projects

I examine the impact of the Affordable Care Act’s Medicaid expansion on maternal and fetal health outcomes using National Center for Health Statistics Natality data from 2006 to 2023. I exploit staggered state adoption as a quasi-experiment, and the staggered differences-in-differences estimates indicate an increase in the share of Medicaid births but broadly no impact on maternal prenatal care, maternal health, and fetal health. The absence of statistically significant effects is consistent across heterogeneity groups. These null findings indicate that expanded insurance access through the Affordable Care Act may be insufficient to improve health outcomes. I do find a statistically …


The Evolving Roles Of U.S. Academic Librarians: A Snapshot Of Job Responsibilities In 2023, Russell Michalak, Laura Rose Taylor, Michelle Reed, Amanda Koziura, Devon Ellixson Jan 2026

The Evolving Roles Of U.S. Academic Librarians: A Snapshot Of Job Responsibilities In 2023, Russell Michalak, Laura Rose Taylor, Michelle Reed, Amanda Koziura, Devon Ellixson

Library Faculty Research

This study examines the evolving roles of academic librarians across North America. Adapting a survey tool published in a prior Canadian study, it surveys over 350 librarians in the United States, analyzing shifts in Research Support, Teaching and Learning, Digital Scholarship, User Experience, and Scholarly Communication. Results indicate significant engagement in information discovery and digital scholarship with a growing need for training in digital tools and data management. The resulting report highlights the crucial role of academic librarians in adapting to technological and educational changes, underscoring the necessity for ongoing professional development.


Foreword, Jli Vol. 44 Editorial Board Jan 2026

Foreword, Jli Vol. 44 Editorial Board

Minnesota Journal of Law & Inequality

No abstract provided.


Illuminating The Errors Of State V. Muñoz And The Curtailment Of Due Process Rights When A U.S. Citizen Is Married To A Noncitizen, Kavya Mahesh Jan 2026

Illuminating The Errors Of State V. Muñoz And The Curtailment Of Due Process Rights When A U.S. Citizen Is Married To A Noncitizen, Kavya Mahesh

Minnesota Journal of Law & Inequality

No abstract provided.


Identifying And Prioritizing Essential Healthcare Services For A Private Start-Up Healthcare Hub In Laxmipasha, Bangladesh, Ferdous Ara Mostofa Jan 2026

Identifying And Prioritizing Essential Healthcare Services For A Private Start-Up Healthcare Hub In Laxmipasha, Bangladesh, Ferdous Ara Mostofa

Dissertations

This quantitative study identifies and prioritizes essential healthcare services for developing a private start-up healthcare hub in Laxmipasha, Bangladesh, a rural community with significant gaps in healthcare access. Using secondary data from national and international sources, the research analyzed disease burden, population characteristics, and service availability to determine the most urgent health priorities. A structured, evidence-based framework was used to evaluate services based on mortality and morbidity, service gaps, and potential health impact. The findings indicate that Maternal and Child Health (MCH), Non-Communicable Disease (NCD) management, and infectious disease control represent the most critical priorities for initial implementation. The study …


Parent Perspectives: Child Attendance In Community Grief Support, Janeene Sanderson Jan 2026

Parent Perspectives: Child Attendance In Community Grief Support, Janeene Sanderson

EWU Masters Thesis Collection

Childhood bereavement can affect children emotionally, socially, and developmentally, creating a need for support that is both age-appropriate and grief-informed. This qualitative study explored how parents perceived the impact of community grief support programs for their bereaved children. The study focused on children ages 8–12 who attended a peer support group, grief camp, or similar community-based grief support program after the death of a loved one. Data were collected through parent interviews and reviewed through thematic analysis. Findings showed that parents perceived these programs as meaningful because they created safe spaces where children could feel normal and validated in their …


Impact Of Protein Corona Morphology On Nanoparticle Diffusion In Biological Fluids: Insights From A Mesoscale Approach, Beatrice Cipriani, Hender Lopez Jan 2026

Impact Of Protein Corona Morphology On Nanoparticle Diffusion In Biological Fluids: Insights From A Mesoscale Approach, Beatrice Cipriani, Hender Lopez

Research Outputs: 2025-Present

Nanoparticles (NPs) demonstrate considerable potential in medical applications, including targeted drug delivery and diagnostic probes. However, their efficacy depends on their ability to navigate through the complex biological environments inside living organisms. In such environments, NPs interact with a dense mixture of biomolecules, which can reduce their mobility and hinder diffusion. Understanding the factors influencing NP diffusion in these environments is key to improving nanomedicine design and predicting toxicological effects. In this study, we propose a computational approach to model NP diffusion in crowded environments. We introduce a mesoscale model that accounts for the combined effects of the protein corona …


Negligible Rebound In Myopia Progression Following Cessation Of Treatment With 0.01% Atropine For 3 Years: Year-4 Results From The Champ Phase 3 Clinical Trial, Champ Trial Group Investigators, Karla Zadnik, Erica Schulman, Ian Flitcroft, Jennifer S. Fogt, Louis C. Blumenfeld, Tung M. Fong, Eric Lang, Simon P. Chandler, Houman D. Hemmati Jan 2026

Negligible Rebound In Myopia Progression Following Cessation Of Treatment With 0.01% Atropine For 3 Years: Year-4 Results From The Champ Phase 3 Clinical Trial, Champ Trial Group Investigators, Karla Zadnik, Erica Schulman, Ian Flitcroft, Jennifer S. Fogt, Louis C. Blumenfeld, Tung M. Fong, Eric Lang, Simon P. Chandler, Houman D. Hemmati

Research Outputs: 2025-Present

Introduction: Stage 2 of the Childhood Atropine for Myopia Progression (CHAMP) study was conducted to observe the safety, efficacy and rebound effects of low-dose atropine sulphate ophthalmic solutions (0.01% and 0.02%) for paediatric myopia in the year following cessation of 3 years of prior treatment. Methods: The study was a multicentre, randomised, double-masked, placebo-controlled Phase 3 clinical trial. Children aged 3 to < 17 years with myopia (spherical equivalent refractive error (SER) from −0.50 to −6.00 D) who entered and completed Stage 1 (3 years of treatment) participated in the fourth-year follow-up (Stage 2). Stage 1 participants who were treated with atropine 0.01% or 0.02% were re-randomised 1:1:1 to atropine 0.01%, atropine 0.02% or vehicle in Stage 2. Stage 1 vehicle-treated participants were re-randomised 1:1 to atropine 0.01% or atropine 0.02% in Stage 2. Outcomes included changes in cycloplegic SER, changes in axial length (AL), responder status continuity and progression to high myopia. Results: Four hundred and twenty participants were randomised in Stage 2. Negligible rebound was observed among the participants who switched from 0.01% atropine to vehicle compared to those who continued on 0.01% atropine treatment (least square mean difference in SER change from Month 36 to Month 48 between continued treatment and switching to vehicle = 0.019 D, 95% CI [−0.14, 0.18], p = 0.82 for the modified Intent to Treat set). Stage 1 responders remained responders in 83-90% of participants in various Stage 2 groups. Safety profiles were favourable, with mild, transient adverse events. Conclusions: Atropine sulphate ophthalmic solution (0.01%) exhibited negligible rebound in myopia progression after treatment cessation following 3 years of continued treatment, highlighting its potential as a treatment option. The treatment maintained a favourable safety record, and the overall benefit and risk assessment support its potential use as a long-term myopia management option. Clinical trial registration: The Childhood Atropine for Myopia Progression (CHAMP) study was registered in clinicaltrials.gov (NCT03350620, registration date November 17, 2017).


Analytical Commentary And Performer's Guide To Carlos R. Martinez's Four Pieces For Trombone, Bailey Jean Hardy-Price Jan 2026

Analytical Commentary And Performer's Guide To Carlos R. Martinez's Four Pieces For Trombone, Bailey Jean Hardy-Price

Theses and Dissertations--Music

Musicians with hearing loss are documented in prominent figures, such as Ludwig van Beethoven. In the age of developing medical technology, hearing aids can turn the course for many musicians. Music can serve as an audio medium for this journey.

Carlos R. Martinez (b. 1978) is an active composer and pianist commissioned to create a piece that explores the journey of hearing loss in a musician. Martinez’s Four Pieces for Trombone and Piano illustrate a musician’s discovery of their hearing loss, its consequences, and joy in implementing the use of a hearing aid. The detailed discussion of the composer and …