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Minutes, Curriculum Committee Meeting, Tuesday, January 27, 2026, Curriculum Committee Jan 2026

Minutes, Curriculum Committee Meeting, Tuesday, January 27, 2026, Curriculum Committee

Curriculum Committee Minutes

No abstract provided.


Committee Meeting Minutes 1-27-26, Unk Student Government Jan 2026

Committee Meeting Minutes 1-27-26, Unk Student Government

Committee Meeting Minutes

No abstract provided.


Through The Ages: Reflecting On 250 Years Of Ai Technology, Ethan Brue Jan 2026

Through The Ages: Reflecting On 250 Years Of Ai Technology, Ethan Brue

Faculty Work Comprehensive List

"The only thing historians know for certain is that humans have been proven quite inept at being certain, particularly when it involves the future."

Posting about the longterm influence of artificial intelligence from In All Things, an online hub that offers insight into maintaining and faithful and orthodox Reformed Christian worldview while fearlessly engaging in every aspect of contemporary life – until all is made new.

Through the Ages


Predictions Of Masses For Light Hybrid Baryons, Qi-Nan Wang, Ding-Kun Lian, Wei Chen, Hui-Min Yang, Hua-Xing Chen, Jason N.E. Ho, T. G. Steele Jan 2026

Predictions Of Masses For Light Hybrid Baryons, Qi-Nan Wang, Ding-Kun Lian, Wei Chen, Hui-Min Yang, Hua-Xing Chen, Jason N.E. Ho, T. G. Steele

Faculty Work Comprehensive List

Within the method of parity-projected QCD sum rules, we study the mass spectra of light hybrid baryons with 𝐼⁡(𝐽𝑃) =1/2⁢(1/2±),3/2⁢(1/2±),1/2⁢(3/2±),3/2⁢(3/2±) by constructing the local 𝑞⁢𝑞⁢𝑞⁢𝑔 interpolating currents. We calculate the correlation functions up to dimension eight condensates at the leading order of 𝛼𝑠. The stable QCD Lapalce sum rules can be established for the positive-parity 𝑁1/2+,Δ3/2+,Δ1/2+ and negative-parity 𝑁1/2−,𝑁3/2−,Δ1/2− channels to extract their mass spectra. The lowest-lying hybrid baryons are predicted to be the positive-parity 𝑁1/2+ state around 2.01 GeV. These hybrid baryons mainly decay into conventional baryon plus meson final states. We propose to search for the light hybrid …


Redefining The Role Of Chaperones For Dot/Icm T4bss-Mediated Substrate Translocation By Legionella Pneumophila, Sukhithasri Vijayrajratnam, Ahmet Hasanovic, Joseph P Vogel Jan 2026

Redefining The Role Of Chaperones For Dot/Icm T4bss-Mediated Substrate Translocation By Legionella Pneumophila, Sukhithasri Vijayrajratnam, Ahmet Hasanovic, Joseph P Vogel

2020-Current year OA Pubs

Legionella pneumophila, the etiological agent of legionnaires' disease, establishes its intracellular niche through the Dot/Icm type IVB secretion system, which translocates ∼300 effector proteins into host cells. Efficient secretion of many effectors requires the IcmS and IcmW chaperones, which interact with both substrates and the type IV coupling protein DotL. A prior model proposed that IcmSW are released from substrates during translocation by transfer to the C terminus of DotL and then recycled to the cytoplasm. This model predicts an excess cytoplasmic pool of IcmSW and their dissociation from DotL. We tested these predictions using quantitative stoichiometric analysis of Dot/Icm …


Ablation Of Cd38 In Multiple Myeloma Cells Leads To An Aggressive Phenotype In A Mouse Xenograft Model, Michael R Dyer, Alex Zheleznyak, Erin N Teubner, Julie L Prior, Brad Manion, Zhenghan Jing, Amit K Sharma, Junwei Du, Rui Tang, Mark A Fiala, John F Dipersio, Deborah Veis, Julie O'Neal, Mikhail Y Berezin, Monica Shokeen Jan 2026

Ablation Of Cd38 In Multiple Myeloma Cells Leads To An Aggressive Phenotype In A Mouse Xenograft Model, Michael R Dyer, Alex Zheleznyak, Erin N Teubner, Julie L Prior, Brad Manion, Zhenghan Jing, Amit K Sharma, Junwei Du, Rui Tang, Mark A Fiala, John F Dipersio, Deborah Veis, Julie O'Neal, Mikhail Y Berezin, Monica Shokeen

2020-Current year OA Pubs

Multiple myeloma (MM) is a plasma cell malignancy characterized by bone pain and end-organ failure. A major challenge in treating MM is therapeutic resistance. CD38-targeted immunotherapies, such as daratumumab, have significantly improved outcomes; however, variable responses, resistance, and relapse remain vital challenges. We hypothesized that loss of CD38 drives a more aggressive phenotype and resistance to therapy. To test this, we developed a CD38 knockout (KO) clone of a human MM cell line and evaluated it in immunodeficient mice. Mice with CD38 KO tumors exhibited an increased tumor burden and reduced survival compared with those with CD38 wild-type (WT) tumors. …


Expression Spectrum Of Te-Driven Transcripts In Human Adult Tissues, Yushan Yang, Tao P Wu, Bo A Zhang Jan 2026

Expression Spectrum Of Te-Driven Transcripts In Human Adult Tissues, Yushan Yang, Tao P Wu, Bo A Zhang

Faculty, Staff and Students Publications

Background

Transposable elements (TEs) are vital components of eukaryotic genomes and have played a critical role in genome evolution. Although most TEs are silenced in the mammalian genome, increasing evidence suggests that certain TEs are actively involved in gene regulation during early developmental stages. However, the extent to which human TEs drive gene transcription in adult tissues remains largely unexplored.

Results

In this study, we systematically analyze 17,329 human transcriptomes to investigate how TEs influence gene transcription across 47 adult tissues. Our findings reveal that TE-driven transcripts are broadly expressed in human tissues, contributing to both housekeeping functions and tissue-specific …


Effects Of Leucine Supplementation On Athletic Performance, Central Fatigue, And Serum Metabolism In Endurance Athletes: A Randomized Controlled Trial And Targeted Metabolomics Study, Tieying Li, Wei Xu, Jun Chen, Zhaobo Kan, Xuemei Sui, Zhiguang Zhao, Qirong Wang Jan 2026

Effects Of Leucine Supplementation On Athletic Performance, Central Fatigue, And Serum Metabolism In Endurance Athletes: A Randomized Controlled Trial And Targeted Metabolomics Study, Tieying Li, Wei Xu, Jun Chen, Zhaobo Kan, Xuemei Sui, Zhiguang Zhao, Qirong Wang

Faculty Publications

Objectives: We aimed to investigate the effects of 6 weeks of leucine supplementation on athletic performance, central fatigue, and serum metabolome in endurance athletes, and to provide valuable insights into nutritional strategies for endurance athletes. Methods: Twenty cross-country skiers were recruited and randomized into 2 groups: the placebo (PLA) group and the leucine (LEU) group. Subjects were given leucine (8.5 g) + sucrose (14 g) or only sucrose (14 g) supplements twice each day from Monday to Saturday for 6 weeks. Test parameters include body composition, aerobic capacity, isokinetic muscle strength, blood biochemistry, and targeted metabolomics. Results: After intervention, compared …


Surviving Staten Island: Black Women’S Narratives Of Resilience, Motherwork, And Embodied Trauma, Jazmin Rivera Jan 2026

Surviving Staten Island: Black Women’S Narratives Of Resilience, Motherwork, And Embodied Trauma, Jazmin Rivera

Student Theses

This oral history dissertation centers the experiences of six Black women who had formative experiences navigating hostile school and community-based settings on Staten Island during the 1970s, 1980s, and early 1990s. Guided by a conceptual framework that draws on Black orality, Black feminist thought, and endarkened feminist epistemology, this study demonstrates how Black women were required to cross geographic and social boundaries to survive hostile conditions in Staten Island communities and schools. Findings from this study highlight Black women’s use of community cultural wealth to inform their survival strategies and resilience. At the same time, their experiences indicate the potential …


Pandemic Mask Mandates And Closures Were Linked To Increased Gun Violence, Douglas A. Wolf, Emily W. Wiemers, Iliya Gutin, Jennifer Karas Montez, Shannon M. Monnat Jan 2026

Pandemic Mask Mandates And Closures Were Linked To Increased Gun Violence, Douglas A. Wolf, Emily W. Wiemers, Iliya Gutin, Jennifer Karas Montez, Shannon M. Monnat

Population Health Research Brief Series

Gun violence worsened substantially during the COVID-19 pandemic. This brief summarizes findings from a study using weekly gun violence casualty data from 2016-2021 for 304 U.S. counties from the Gun Violence Archive and COVID-19 policy data from county-level measures of activity restrictions and masking requirements. The authors find that policies requiring masking and activity restrictions were associated with significant increases in gun violence. Indoor masking requirements were linked to a 28% increase in gun violence, while activity restrictions were associated with a 4.2% increase.


Shoreline Energy, Steven Gellman Jan 2026

Shoreline Energy, Steven Gellman

Stimulus: A Medical Humanities Journal

No abstract provided.


Atlanta '96: The Games And The South, Beau Bowden Jan 2026

Atlanta '96: The Games And The South, Beau Bowden

ETDs from 2020-2029

The Centennial Olympiad, hosted by Atlanta, Georgia, in 1996, demonstrated key principles of the postsouthern mindset, a movement typically associated with literary criticism that, if applied to historiographic methods, offers valuable insights into how Atlantans confronted competing identities of being a modern international city hailed as the Black Mecca, and a city forever linked to the Lost Cause, Ku Klux Klan, and racial inequality. During the Opening Ceremonies, specifically, Olympic organizers curated a celebration touting the city’s and region’s multiculturalism and corporate might, as described by the Atlanta Committee for the Olympics (ACOG), the body responsible for organizing the games, …


Expanding Access To Live Donation Opportunities: Implementing Telehealth Solutions To Enhance The Living Donor Navigator Program, Alexis Carter Jan 2026

Expanding Access To Live Donation Opportunities: Implementing Telehealth Solutions To Enhance The Living Donor Navigator Program, Alexis Carter

ETDs from 2020-2029

Living donor kidney transplantation (LDKT) is the most effective treatment for patients with end-stage kidney disease; however, living donation rates have remained suboptimal over the past two decades. As a result, many interventions have been developed and tailored to increase living donation. The Living Donor Navigator (LDN) Program is one effort designed to help transplant candidates identify potential living donors and guide them through the donation process, using a combination of advocacy and systems training. The LDN Program is a lay-navigator-based intervention that equips participants with the knowledge, communication skills, and confidence needed to identify and engage potential living donors. …


Bright Eyes And The Kinfolk, Ariel Aileen Cochran Jan 2026

Bright Eyes And The Kinfolk, Ariel Aileen Cochran

ETDs from 2020-2029

BRIGHT EYES AND THE KINFOLK ARIEL COCHRAN MASTER OF ARTS IN ENGLISH – CREATIVE WRITING ABSTRACT Bright Eyes and The Kinfolk is a historical fiction set in the pre-Civil War South that pays homage to Western media including, but not limited to, Gunsmoke, The Virginian, The Rifleman, Two Mules For Sister Sara, and Tombstone. The story follows the enslaved Dahomey (modern Benin) African Tina Jones who is in search of Uyi, her younger brother that was recently sold off from the Jones plantation in Mobile, Alabama. With a lead pointing to the state of Texas, Tina sets out west and …


Novel Retinal Biomarker Development In Early Alzheimer’S Disease, Swetha Ravichandran Jan 2026

Novel Retinal Biomarker Development In Early Alzheimer’S Disease, Swetha Ravichandran

ETDs from 2020-2029

Alzheimer’s disease is a progressive neurodegenerative disorder that causes damage to the neurons that are present in the brain. Progress in the management and treatment of AD is limited by lack of early diagnostics, which are critical to the development of effective therapies. It is therefore critical to develop non-invasive/cost efficient biomarkers to aid in early diagnosis and interventions to prevent or delay dementia onset. While Positron Emission Tomography (PET) and cerebrospinal fluid assessment have greatest utility, they are not routinely used because they are expensive and invasive, respectively. Retinal imaging offers a promising, low-cost, and non-invasive avenue for detecting …


Early Life Stress Mediates Cardiovascular Disease Risk Through Csf1r And Increases Risk Of Lupus Through Mature B-Cells, Cailin Elizabeth Kellum Jan 2026

Early Life Stress Mediates Cardiovascular Disease Risk Through Csf1r And Increases Risk Of Lupus Through Mature B-Cells, Cailin Elizabeth Kellum

ETDs from 2020-2029

The term Early Life Stress (ELS) encompasses traumatic events occurring before the age of 18 such as physical abuse, verbal abuse, household dysfunctions, sexual abuse, childhood neglect, child maltreatment, and adverse childhood experiences. The traumatic psychological and physical experiences in early life are widely known to cause enduring effects on mental and physical health in adulthood. Of note, individuals with ELS have adverse health outcomes earlier in adulthood and with more severity such as in the case of Systemic Lupus Erythematous (SLE), an autoimmune disease. The risk for autoimmunity and cardiovascular disease (CVD) increases with ELS exposure and CVD is …


Awareness And Knowledge Of Juvenile Idiopathic Arthritis Among Orthodontic And Oral And Maxillofacial Surgery Specialties In The United States., Kavita Nayar Jan 2026

Awareness And Knowledge Of Juvenile Idiopathic Arthritis Among Orthodontic And Oral And Maxillofacial Surgery Specialties In The United States., Kavita Nayar

ETDs from 2020-2029

Introduction: Juvenile Idiopathic Arthritis (JIA) is the most common chronic pediatric arthritis, frequently involving the temporomandibular joint (TMJ) and resulting in facial growth disturbances, functional impairment, and complex multidisciplinary treatment needs. Despite its clinical relevance, limited awareness and inconsistent management strategies exist among specialists who are involved in the care of these patients including orthodontists, oral and maxillofacial surgeons and rheumatologists. This study aimed to evaluate the understanding, knowledge and interdisciplinary management practices between board-certified orthodontists and oral and maxillofacial surgeons (OMSs) across the United States regarding JIA. Materials and Methods: A cross-sectional survey was distributed electronically via Qualtrics to …


Reagan, Bush, Gorbachev, And The End Of The Cold War, Joshua Caleb Teasley Jan 2026

Reagan, Bush, Gorbachev, And The End Of The Cold War, Joshua Caleb Teasley

ETDs from 2020-2029

This work addresses key questions relating to the end of the Cold War. Contemporary wisdom suggests that Ronald Reagan’s policies beat the Soviet Union into submission, but this is not the case. Reagan’s initial policies were antagonistic towards the Soviet Union and his devotion to SDI later harmed his ability to establish relations with Michail Gorbachev later on. This thesis argues that it was George H.W. Bush, rather than Reagan, who was the more influential and effective President when dealing with the Soviet Union. Bush’s diplomacy was less idealized and more realistic than Reagan’s. Additionally, Bush was able to successfully …


Relationship Between Corneal Biomechanics In Sjögren’S Disease And Risk Factors For Glaucoma Development, Isabella Grace Simmons Jan 2026

Relationship Between Corneal Biomechanics In Sjögren’S Disease And Risk Factors For Glaucoma Development, Isabella Grace Simmons

ETDs from 2020-2029

Both Sjögren’s disease and glaucoma are known to have abnormal corneal biomechanics that impact their disease progression. The pathophysiology of Sjögren’s disease may also increase the likelihood of developing glaucoma. However, we do not yet know whether the prevalence of risk factors associated with glaucoma in Sjögren’s patients is due to underlying weakened corneal biomechanics. Oculus Corvis ST will be used to evaluate the corneal biomechanics in Sjögren’s patients in relation to the inflammatory mediators in the tear film. These properties will then be correlated with retinal nerve fiber layer and ganglion cell layer thickness. Evaluating these findings will provide …


Lmod1 Modulates Neointimal Lesion Size After Vessel Injury And Stabilizes Smooth Muscle Cell Gene Regulatory Networks During Atherogenic Stress, Sara Wennersten Jan 2026

Lmod1 Modulates Neointimal Lesion Size After Vessel Injury And Stabilizes Smooth Muscle Cell Gene Regulatory Networks During Atherogenic Stress, Sara Wennersten

ETDs from 2020-2029

Phenotypic switching of smooth muscle cells (SMCs) from a contractile to a synthetic state underlies the pathogenesis of several cardiovascular disease (CVD) pathologies, including restenosis and atherosclerosis. Leiomodin 1 (LMOD1), an SMC-enriched actin-binding protein, has been previously found to regulate SMC phenotypic modulation in vitro. However, its contribution to CVD development and progression, along with its influence on gene regulatory networks (GRNs) that inform underlying responses to stress, remains incompletely defined. Here, I combine a mouse injury model, bulk RNA sequencing, and GRN inference to define how reduced LMOD1 expression perturbs SMC physiology during vascular wall remodeling and lipid stress. …


David Cruz Perez V. Attorney General United States Of America Jan 2026

David Cruz Perez V. Attorney General United States Of America

2026 Decisions

Agency


William Richter V. Duquesne University Of The Holy Spirit Jan 2026

William Richter V. Duquesne University Of The Holy Spirit

2026 Decisions

USDC for the Western District of Pennsylvania


Letter To The Editor From Dr. Gellman, The Stimulus Team Jan 2026

Letter To The Editor From Dr. Gellman, The Stimulus Team

Stimulus: A Medical Humanities Journal

No abstract provided.


Knowledge (Ilm) And Experience (Selfactualization), Mahdi Dezham Dds Jan 2026

Knowledge (Ilm) And Experience (Selfactualization), Mahdi Dezham Dds

Stimulus: A Medical Humanities Journal

No abstract provided.


Autumn’S Embrace, Sarah C. Le Jan 2026

Autumn’S Embrace, Sarah C. Le

Stimulus: A Medical Humanities Journal

No abstract provided.


Letter From The Stimulus Team, The Stimulus Team Jan 2026

Letter From The Stimulus Team, The Stimulus Team

Stimulus: A Medical Humanities Journal

No abstract provided.


The Beauty Of Music, Anna Nguyen Jan 2026

The Beauty Of Music, Anna Nguyen

Stimulus: A Medical Humanities Journal

No abstract provided.


In All The Ways You Are Gone And Still Here__A Poem In The Perspective Of A Loved One, Somotochi Alozie Jan 2026

In All The Ways You Are Gone And Still Here__A Poem In The Perspective Of A Loved One, Somotochi Alozie

Stimulus: A Medical Humanities Journal

No abstract provided.


Snipped Away, Jennifer Nguyen, Anthony Nguyen Jan 2026

Snipped Away, Jennifer Nguyen, Anthony Nguyen

Stimulus: A Medical Humanities Journal

No abstract provided.


A Collection Of Unheard Voices In Medicine, Ibukunoluwa F. Oyeyemi, Opeoluwa L. Oyeyemi, Oreoluwa H. Oyeyemi Jan 2026

A Collection Of Unheard Voices In Medicine, Ibukunoluwa F. Oyeyemi, Opeoluwa L. Oyeyemi, Oreoluwa H. Oyeyemi

Stimulus: A Medical Humanities Journal

No abstract provided.