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On Neurosurgery, Ogan Gurel Md, Arinze Awagu Jan 2026

On Neurosurgery, Ogan Gurel Md, Arinze Awagu

Stimulus: A Medical Humanities Journal

No abstract provided.


Instrument Of Nutriment, Jessica Nwankwo Jan 2026

Instrument Of Nutriment, Jessica Nwankwo

Stimulus: A Medical Humanities Journal

No abstract provided.


Reliance, Misplaced: Restoring The Text Of The Antifraud Provisions Of The Federal Securities Laws In Sec Enforcement Actions, Christopher R. Mills Jan 2026

Reliance, Misplaced: Restoring The Text Of The Antifraud Provisions Of The Federal Securities Laws In Sec Enforcement Actions, Christopher R. Mills

University of Miami Business Law Review

The antifraud provisions of the federal securities laws are statutory sledgehammers. Those who violate them can face severe sanctions, including ruinous monetary penalties and others that can effectively bar firms and individuals from the securities industries. The Securities and Exchange Commission is authorized to enforce these provisions with the full weight of the federal government. And the SEC does so vigorously.

Even though the antifraud provisions target fraud, for decades lower courts and the Commission have held that the Commission can establish violations of them without any evidence that anyone was misled. They have done so by concluding that, unlike …


Metal Free Multicomponent C-C And C-N Bond Formation Via Cross – Coupling And Cross – Dehydrogenative Coupling Methodologies For The Synthesis Of Diversely Functionalized N – And O – Heterocyclic Compounds, Reicha Pandey Ms Jan 2026

Metal Free Multicomponent C-C And C-N Bond Formation Via Cross – Coupling And Cross – Dehydrogenative Coupling Methodologies For The Synthesis Of Diversely Functionalized N – And O – Heterocyclic Compounds, Reicha Pandey Ms

Theses and Dissertations

Heterocyclic compound is a significant domain of organic chemistry that focuses with synthetic, design and characteristics. This molecule is characterized by ring structure including one or more atom of an elements other than carbon (C), typically nitrogen (N), Oxygen (O) or Sulphur (S). The synthesis of heterocyclic compound via sustainable strategy encompasses various approaches such as design and implementation of real time analysis aimed at pollution prevention. It demonstrates wide range of medicinal application by showing various activities such as anticancer, anti-inflammatory, anti-microbial and many more. Additionally, many functional materials including dye, polymers etc. are the other application of heterocyclic …


1/27/2026 Joint Senate Meeting, Unk Student Government Jan 2026

1/27/2026 Joint Senate Meeting, Unk Student Government

Joint Senate Meeting Minutes

No abstract provided.


Promoting Yourself As A Scholar And Researcher, Matthew Farber Jan 2026

Promoting Yourself As A Scholar And Researcher, Matthew Farber

Bear GRADS

This session provides strategies for effectively promoting yourself as a scholar and researcher, with a focus on building visibility, credibility, and impact. Participants will explore practical approaches, including crafting an academic identity, leveraging digital platforms, and communicating research effectively to various audiences, as well as how to intentionally self-present to enhance professional opportunities and scholarly recognition.


“Am I Good Enough To Be Here?”: A Photovoice Project On Disability And Belonging In Higher Education (Plain Language Summary), Sylvia Mac Ph.D., Niki Elliott Ph.D. Jan 2026

“Am I Good Enough To Be Here?”: A Photovoice Project On Disability And Belonging In Higher Education (Plain Language Summary), Sylvia Mac Ph.D., Niki Elliott Ph.D.

Inclusion in Postsecondary Education

Many college students with disabilities face invisible barriers that go beyond access to ramps or extra time on tests. This study asked: How do students with disabilities actually feel in higher education? Do they feel safe? Do they feel like they belong? Do they feel liked?

Six students at a small private university shared their stories and took photographs over several weeks, using a method called Photovoice. These images, combined with interviews, reveal how deeply ableism and exclusion impact their sense of safety, belonging, and worth.

The study used polyvagal theory, which explains how our nervous systems respond to environments. …


Unh Online Degree Programs Ranked Among Best In State And Region, Robbin Ray Jan 2026

Unh Online Degree Programs Ranked Among Best In State And Region, Robbin Ray

Media Relations

No abstract provided.


The “20 Magic Prompts”, Yoshihiko Ariizumi Jan 2026

The “20 Magic Prompts”, Yoshihiko Ariizumi

Learning, Teaching, & Researching Optimization

This list provides 20 intuitive prompts designed to help you recognize Divine handiwork and personal growth amidst the chaos of daily life. By selecting just one or two questions each night, you transform fleeting experiences into "lifetime wisdom" and deepen your dialogue with Heavenly Father. It serves as a practical tool to shift from a passive passenger to a proactive driver, grounding your spiritual insights into a concrete narrative.


January 27, 2026, Pacific Global Jan 2026

January 27, 2026, Pacific Global

Pacific Global Newsletter

No abstract provided.


Land Use And Sovereignty Along The Catawba River, Thomas C. Brugh, Lucile C. Rencher Jan 2026

Land Use And Sovereignty Along The Catawba River, Thomas C. Brugh, Lucile C. Rencher

Student Scholarship

This document-based case study explains how land-use change along the Catawba River Corridor (Lancaster and York Counties, South Carolina) has been produced through the interaction of property rights (dominium) and rule-setting authority (imperium), showing why sovereignty continues to shape development even after land disputes appear “settled.” Through analyzing legal records (Treaty of Nation Ford, the 1959 Catawba Division of Assets Act, the 1986 Supreme Court timing decision, and the 1993 Settlement Act), planning documents, parcel records, and field observations, we trace how shifting jurisdiction and title certainty structured what kinds of land uses were possible and when. We argue that …


Common Octopus (Octopus Vulgaris) Blooms Off The Southwest Of The Uk: History, Trends, Causes And Consequences.: Report On Work Package 1: History, Causes And Consequences Of Octopus Blooms, Bryce Stewart, Simon Thomas, Tim J. Smyth, Molly K. James, Emma Sullivan, Alice Hall, Tully Osmond, Emma Sheehan Jan 2026

Common Octopus (Octopus Vulgaris) Blooms Off The Southwest Of The Uk: History, Trends, Causes And Consequences.: Report On Work Package 1: History, Causes And Consequences Of Octopus Blooms, Bryce Stewart, Simon Thomas, Tim J. Smyth, Molly K. James, Emma Sullivan, Alice Hall, Tully Osmond, Emma Sheehan

School of Biological and Marine Sciences

Common octopus (Octopus vulgaris) are normally uncommon in UK waters, with a mainly south-westerly distribution linked to the species’ preference for warmer conditions. However, a major population bloom occurred off southwest UK in 2025, comparable to rare historical blooms recorded in 1899–1900, 1932–33 and 1950–51. The species’ rapid growth, high fecundity and short lifespan make its populations highly responsive to environmental conditions. Evidence from fisheries landings, scientific surveys and citizen science confirmed the bloom, with commercial fisheries landings of common octopus in 2025 being almost 65 times higher than recent annual averages. The 2025 bloom and all previous blooms were …


Association Of Hair Shedding Level With Cow–Calf Performance In Summer-Bred Dexter Cattle, Ichard Browning Jr, Emily G. Hayes, Kaylee S. Hillin, Maria Lenira Leite-Browning Jan 2026

Association Of Hair Shedding Level With Cow–Calf Performance In Summer-Bred Dexter Cattle, Ichard Browning Jr, Emily G. Hayes, Kaylee S. Hillin, Maria Lenira Leite-Browning

Food and Animal Sciences Faculty Research

Reduced winter hair shedding in beef cows through the spring and summer months may contribute to heat stress and reduced performance in spring-calving herds. This study evaluated the relationship of hair shedding with the fertility and maternal performance of 72 Dexter cows. Hair shedding data for 20 May, 3 June, 17 June, and 1 July in 2019 were used to classify cows as high or low hair shedders. Hair shedding levels were lower (p < 0.05) for 2-year-old cows than for cows 7+ years of age for the first three dates and lower (p ≤ 0.05) for lactating cows than for dry cows on the first two dates. Concurrent and four years of historical performance records were used to assess the associations between hair shedding and cow–calf performance. Data from 230 natural matings in July and August from 2015 to 2019 were analyzed. Birth to weaning weight data were recorded from 2016 to 2019 on 124 spring-born calves. Cow fertility was higher (p < 0.05) for high-shed cows than for low-shed cows for the 1 July classification. When the records from cows that were dry in 2019 were excluded from testing, fertility was higher (p < 0.05) for high-shed cows than for low-shed cows at all four scoring dates. The associations of cow hair shedding levels with preweaning calf performance were minimal. Dexter cows exhibiting higher hair shedding levels in the spring and summer expressed higher summer fertility.


N-Acetylcysteine Is Associated With Changes In Functional Connectivity In Patients With Parkinson's Disease, Daniel A. Monti, George Zabrecky, Daniel Kremens, Tsao-Wei Liang, Nancy A. Wintering, Faezeh Vedaei, Emily Navarreto, Monisha Gupta, Alicia Steinmetz, Anthony J. Bazzan, Feroze Mohamed, Andrew B. Newberg Jan 2026

N-Acetylcysteine Is Associated With Changes In Functional Connectivity In Patients With Parkinson's Disease, Daniel A. Monti, George Zabrecky, Daniel Kremens, Tsao-Wei Liang, Nancy A. Wintering, Faezeh Vedaei, Emily Navarreto, Monisha Gupta, Alicia Steinmetz, Anthony J. Bazzan, Feroze Mohamed, Andrew B. Newberg

Marcus Institute of Integrative Health Faculty Papers

INTRODUCTION: This study assessed the changes in functional connectivity from resting functional magnetic resonance imaging (fMRI) in patients with Parkinson's disease (PD) given N-Acetylcysteine (NAC), the prodrug to L-cysteine and a precursor to the natural biological antioxidant glutathione (GSH). The aim of this study was to determine whether NAC is associated with changes in functional connectivity, particularly in the basal ganglia, and improvements in Parkinson's symptoms.

METHODS: Forty-four patients with PD were randomized to either weekly intravenous infusions of NAC (50 mg/kg) plus oral doses (500 mg twice per day) for six months plus standard of care, or standard of …


Epidermal Growth Factor Receptor Regulates Beclin-1 In Hyperoxic Acute Lung Injury., Zachary M Harris, Asawari Korde, Johad Khoury, Edward P Manning, Gail Stanley, Yosep Shin, Kennedy Mitchell, Alexa Von Der Schulenburg, Ying Sun, Buqu Hu, Hyeon Jun Shin, John Joerns, Brian Clark, Lindsey Placek, Derya Unutmaz, Aigul Moldobaeva, Lokesh Sharma, Maor Sauler, Govindarajan Rajagopalan, Xuchen Zhang, He Wang, Mahboobe Ghaedi, Min-Jong Kang, Jonathan L Koff Jan 2026

Epidermal Growth Factor Receptor Regulates Beclin-1 In Hyperoxic Acute Lung Injury., Zachary M Harris, Asawari Korde, Johad Khoury, Edward P Manning, Gail Stanley, Yosep Shin, Kennedy Mitchell, Alexa Von Der Schulenburg, Ying Sun, Buqu Hu, Hyeon Jun Shin, John Joerns, Brian Clark, Lindsey Placek, Derya Unutmaz, Aigul Moldobaeva, Lokesh Sharma, Maor Sauler, Govindarajan Rajagopalan, Xuchen Zhang, He Wang, Mahboobe Ghaedi, Min-Jong Kang, Jonathan L Koff

Faculty Research 2026

BACKGROUND: While delivery of supplemental oxygen is a life-saving therapy, exposure to high oxygen, called hyperoxia, leads to increased intensive care unit mortality. Hyperoxia induces oxidant-mediated acute lung injury (ALI) and pulmonary cell death, called hyperoxic ALI (HALI). Elucidating molecular mechanisms in HALI could identify therapeutic targets in ALI.

METHODS: In the current study, we examined in vivo effects of HALI on Beclin-1 (BCN1), which regulates autophagy, and modulation of BCN1 by epidermal growth factor receptor (EGFR). Effects of HALI on BCN1 and autophagy were examined in mice with genetically decreased EGFR (EGFR

RESULTS: In WT, HALI led to increased …


Optimizing Practice Facilitation: A Comprehensive Study On Implementation Fidelity And Its Determinants, Demetria Marie Hubbard Jan 2026

Optimizing Practice Facilitation: A Comprehensive Study On Implementation Fidelity And Its Determinants, Demetria Marie Hubbard

ETDs from 2020-2029

Intervention outcomes cannot be fully understood without examining how implementation strategies are delivered. While implementation fidelity to interventions is well recognized as a determinant of effectiveness, the fidelity of implementation strategies—the methods used to support intervention adoption—remains under-documented and under-assessed. Without this information, it is difficult to contextualize why interventions succeed or fail across diverse settings. This three-paper dissertation focuses on practice facilitation (PF), a widely used strategy in primary care quality improvement, as implemented in the Heart Health Improvement Project (HHIP) in Alabama. HHIP, led by the Alabama Cardiovascular Cooperative and funded by the Agency for Healthcare Research and …


Integrated Proteomics To Understand The Role Of Neuritin-1 (Nrn1) As A Molecular Mediator Of Synaptic Resilience In Alzheimer’S Disease, Derian Pugh Jan 2026

Integrated Proteomics To Understand The Role Of Neuritin-1 (Nrn1) As A Molecular Mediator Of Synaptic Resilience In Alzheimer’S Disease, Derian Pugh

ETDs from 2020-2029

Alzheimer’s disease (AD) is the leading cause of dementia in adults over the age of 65, and currently affects approximately 6.9 million people in the United States. By 2060, the number of people age 65 and older with AD is projected to reach 13.8 million, barring the development of disease-altering therapies to prevent, slow or cure AD. Thus, there is a need for progress in the understanding of AD pathophysiology, as well as in the development of diagnostic and therapeutic interventions. Approximately one-third of individuals without dementia at the time of death are found to harbor high levels of amyloid-beta …


Cbct Evaluation Of Planned Vs. Achieved Expansion And Buccal Bone Thickness In Phase I Orthodontic Cases Treated With Clear Aligners, Jared Teeples Jan 2026

Cbct Evaluation Of Planned Vs. Achieved Expansion And Buccal Bone Thickness In Phase I Orthodontic Cases Treated With Clear Aligners, Jared Teeples

ETDs from 2020-2029

Introduction: Within orthodontics, CBCT technology has been used to analyze tooth movement with both fixed appliances and clear aligners. However, little research has evaluated alveolar bone remodeling outcomes in growing patients treated with clear aligner expansion. Methods: This study compared pre-treatment (T0) and post-treatment (T1) CBCTs of Phase I patients treated with clear aligners who had expansion planned in the Invisalign® ClinCheck. CBCTs were collected and analyzed, including 27 maxillary and 22 mandibular arches. The aims were (1) to compare planned vs. actual expansion and (2) to evaluate the arch width (AW) and alveolar bone changes before and after treatment. …


Building An Empire-The Life And Legacy Of Dr. A.G. Gaston, Solymar Ortiz Jan 2026

Building An Empire-The Life And Legacy Of Dr. A.G. Gaston, Solymar Ortiz

ETDs from 2020-2029

The life, work, and legacy of Dr. A.G. Gaston demonstrate the significance of commemorating key civil rights activists through the establishment of historical institutions. Gaston was a pivotal leader in Birmingham’s Civil Rights Movement, and as the first Black millionaire in Alabama, he dedicated his life to generating wealth and uplifting his community. Stemming from humble beginnings, he was raised by formerly enslaved grandparents in a former plantation town. His rough upbringing encompassed a fight against racial injustice, an intense work ethic, and a passion for entrepreneurship. That passion allowed him to build his businesses from the ground up and …


Cysteine Protease Activity In Allergen Recognition And Initiation Of Th2 Allergic Responses, Audrey Rae Meloun Jan 2026

Cysteine Protease Activity In Allergen Recognition And Initiation Of Th2 Allergic Responses, Audrey Rae Meloun

ETDs from 2020-2029

Allergens are non-infectious environmental proteins that can trigger T helper 2 (Th2) cell-mediated inflammation in atopic individuals. Allergens are structurally diverse and typically lack pathogen-associated molecules patterns (PAMPs), which are recognized by pathogen recognition receptors (PRRs). PRRs are the canonical sensors of the innate immune system that typically detect PAMPs in microbes, initiating signaling pathways that drive pathogen clearance. Because allergens generally do not activate PRRs in the same way as infectious agents, alternative detection mechanisms are likely responsible for their recognition and the subsequent initiation of Th2 cell-mediated inflammation. House Dust Mite (HDM), a major indoor allergen, and other …


Exercise Testing And Training For Individuals With Cystic Fibrosis, Najlaa Zayed Alotaibi Jan 2026

Exercise Testing And Training For Individuals With Cystic Fibrosis, Najlaa Zayed Alotaibi

ETDs from 2020-2029

Cystic fibrosis (CF) is a progressive genetic disease that impacts multiple systems (e.g., respiratory system). Hence, routine cardiopulmonary exercise testing (CPET) is recommended to track the disease progression in people with CF. Besides the benefits of exercise testing, exercise training is also beneficial for long-term wellness. It is recommended that people with CF engage in at least 30–60 minutes of aerobic exercise 3 days a week. However, despite the significance of exercise testing and training for people with CF, CPET and exercise training are underutilized in international CF centers. According to the literature, the majority of international CF centers use …


Physical And Psychophysiological Responses To Self-Selected Music In Individuals With Parkinson's Disease, Sophia Porrill Jan 2026

Physical And Psychophysiological Responses To Self-Selected Music In Individuals With Parkinson's Disease, Sophia Porrill

ETDs from 2020-2029

Exercise is a cornerstone adjunct therapy for people with Parkinson’s Disease (PwP). However, exercise capacity is often impaired by non-motor processes including decreased motivation, arousal, and physical effort. Self-selected music (SSM) has been shown to improve motivation and arousal state in healthy individuals thereby leading to increases in exercise capacity. Whether these positive effects of SSM translate to PwP is unclear. The purpose of this study was to measure 1) the psychophysiological effects of SSM at rest, and 2) psychophysiological and physical responses during a 6-minute walk test (6MWT) in PwP. In a counterbalanced crossover manner, PwP (n=12) completed resting …


Analysis Of Activated Carbon Fiber (Acf) As Particulate Filtration And Volatile Organic Compound (Voc) Media For The Development Of A Dual-Air Purifying Facepiece Respirator, Brie Mcmahan Jan 2026

Analysis Of Activated Carbon Fiber (Acf) As Particulate Filtration And Volatile Organic Compound (Voc) Media For The Development Of A Dual-Air Purifying Facepiece Respirator, Brie Mcmahan

ETDs from 2020-2029

Exposure to particulate matter (PM) and volatile organic compounds (VOCs) in occupational or public settings poses adverse health outcomes such as respiratory, cardiovascular, reproductive, neurological, carcinogenic morbidity and mortality. Many occupational settings expose workers to PM and VOC concurrently, yet most commercially available respirators are designed to address either particulates or vapors alone. This includes air-purifying respirators (APRs), powered air-purifying respirators (PAPRs), and filtering facepiece respirators (FFRs) with nuisance-level vapor protection, often limited by bulk, discomfort, high pressure drop, and misuse. We identified a need for alternative dual-exposure media and a respiratory protection device that is lighter, and more comfortable …


Impositions, Christopher Michael Mccauley Jan 2026

Impositions, Christopher Michael Mccauley

ETDs from 2020-2029

This collection explores ordinary moments. A couple on a park bench. A man cleaning a horse stall. A citizen scientist wandering a field. When you peer into these scenes closely, though, you can move beyond the seemingly mundane and discover universal truths, as well as images that evoke shared emotional landscapes. Two primary themes bring greater clarity to these moments and images: people imposing on the world and the world imposing on people. Each piece in the collection touches on these themes in some way. Hence the title, Impositions. I hope readers will feel a sense of empathy for the …


Understanding Mobility Limitations And Public Transportation Accessibility For People With Disabilities, Jada Meria Stringer Jan 2026

Understanding Mobility Limitations And Public Transportation Accessibility For People With Disabilities, Jada Meria Stringer

ETDs from 2020-2029

Mobility for people with disabilities (PWDs) depends on both the availability of transportation and public services and the accessibility of these systems. The presence of public transportation systems does not ensure usability. Vehicles, infrastructure, and the built environment must be designed to accommodate diverse physical, sensory, cognitive, and other needs. PWDs must also be able to navigate public buildings and surrounding spaces safely and comfortably. This thesis examines mobility limitations for PWDs in India and the United States, focusing on accessibility along the full mobility chain. A review of existing literature provides context on accessibility policies, design standards, and the …


Untold Journeys: A Case Study Of Attrition In Alabama’S Public School Teaching Workforce, Jessica Claborn Rose Jan 2026

Untold Journeys: A Case Study Of Attrition In Alabama’S Public School Teaching Workforce, Jessica Claborn Rose

ETDs from 2020-2029

This exploratory multiple-case study investigates the crisis of teacher attrition among early childhood and elementary education graduates from Alabama-based teacher education programs (TEPs) who either avoided public-school teaching or left the profession within three years. The research, guided by Bandura’s social cognitive theory (SCT) and Maslow’s human motivation theory, utilized a qualitative design involving individual interviews with ten teacher leavers (TLs), and five TEP faculty members. The findings reveal that attrition is a multi-faceted crisis rooted in systemic failures, coalescing around two overarching factors: effectiveness of support systems and a collection of barriers. Consistent with SCT, low self-efficacy, resulting from …


Biomineralization Of Low Temperature Plasma(Ltp) Modified Polymeric Biomaterials And Scaffolds, John Patrick Bradford Jan 2026

Biomineralization Of Low Temperature Plasma(Ltp) Modified Polymeric Biomaterials And Scaffolds, John Patrick Bradford

ETDs from 2020-2029

Bio-integration, specifically osseo-integration of bone implants and scaffolds, are vital for the success of implants and bone tissue engineering (BTE). Calcification can be defined as the deposition of calcium compounds as either calcium phosphate(CaP) minerals consisting of hydroxyapatite(HAP) or CaP salts. The significance of the variety of phases of CaP is that mature bone matrix is composed of 65% CaP mineral. Many investigators have attempted to model the natural matrix by producing materials containing calcium phosphate in both amorphous CaP or in the more crystalline HAP form, with biomaterials (both synthetic and biological). Biomimetic CaP formation is a sign of …


Development Of Human Trophoblast Cell Surface Antigen-2 (Trop-2) Specific Radiopharmaceutical Tracers, Arnav Vipulkumar Patel Jan 2026

Development Of Human Trophoblast Cell Surface Antigen-2 (Trop-2) Specific Radiopharmaceutical Tracers, Arnav Vipulkumar Patel

ETDs from 2020-2029

Trophoblast cell surface antigen 2 (Trop2) is closely related to the development and progression of triple-negative breast cancers (TNBC) and is also being investigated as a pan-cancer biomarker. Trop-2 tumorigenesis is mediated by the calcium ion signaling pathways. By accurately predicting and targeting Trop-2 for immunotherapy, precision therapy is crucial. Trop-2 is overexpressed in tumor tissues compared to normal tissues, which makes it a promising molecular target for cancer-targeted therapy. This thesis reports the development and preclinical evaluation of two novel Trop-2-specific radiopharmaceutical tracers derived from the clinically approved antibody-drug conjugate Sacituzumab Govitecan (SG): a full antibody drug conjugate-based tracer …


Volunteer Income Tax Assistance Program Offering Free Tax Assistance Through March 24, James Owsley Boyd Jan 2026

Volunteer Income Tax Assistance Program Offering Free Tax Assistance Through March 24, James Owsley Boyd

Keep Up With the Latest News from the Law School (blog)

Qualifying local taxpayers will again have help navigating federal and state tax returns this spring, as the Volunteer Income Tax Assistance (VITA) program returns to the Indiana University Maurer School of Law.

Both U.S. and certain international taxpayers are eligible to utilize the free services, which will run on Mondays and Tuesdays from 6:30–9:30 p.m. beginning January 26 and continuing through March 24. Services will be available on a first-come, first-served basis in Room 121 on the first floor of the Law School, located at 211 South Indiana Avenue in Bloomington.


Derivative Attorney-Client Privilege In Organizations, Douglas R. Richmond Jan 2026

Derivative Attorney-Client Privilege In Organizations, Douglas R. Richmond

University of Miami Business Law Review

A lawyer and client must be able to communicate about the client’s legal affairs in confidence for the lawyer to be able to meaningfully advise the client, hence courts’ recognition of the attorney-client privilege. Fundamentally, the very term “attorney-client privilege” seemingly requires a lawyer’s participation in a communication for the privilege to attach. But, in fact, lawyers need not always participate in client communications for the attorney-client privilege to shield the communications from discovery. Clients or their employees’ confidential conversations among themselves with respect to legal matters sometimes deserve privilege protection. This derivative application of the privilege can be crucial …