Digital Commons Network^™

Nilotinib-Mediated Reprogramming Of Bone Marrow Macrophages Alters Hematopoietic Stem Cell Fate In Chronic Myeloid Leukemia, Tiffany Davia Ricketts

ETDs from 2020-2029

Tyrosine kinase inhibition (TKI) is highly effective and promotes favorable long-term outcomes for many patients with chronic myeloid leukemia (CML). However, many patients experience treatment resistance or recurrence after TKI cessation due to leukemic stem cell (LSC) persistence within the hematopoietic stem cell (HSC) niche. Within the niche, macrophages adopt different activation states to alter HSC function, however, CML disrupts niche signals to selectively support LSCs and macrophages may contribute to this process. We hypothesize that macrophages contribute to pro-inflammatory activation within the niche to promote LSC development and nilotinib will reprogram macrophages to selectively support non-leukemic stem cells. To …

Conserved Chromatin Programs Orchestrate Cardiac Cell States In Health And Disease And Drive Cardiomyocyte Proliferation After Injury, Xiaoxiao Geng

ETDs from 2020-2029

Chromatin structure is a central regulator of gene expression and cellular identity, yet the chromatin structural factors driving cardiac disease and regeneration remain incompletely defined. This dissertation investigates how modulation of chromatin architecture shapes pathological and regenerative cardiac phenotypes through integrated single-cell transcriptomic, epigenomic, and functional analyses. To determine whether chromatin structural regulators distinguish healthy from diseased cardiac states, we curated a comprehensive list of chromatin structural genes and applied it to single-nuclei RNA sequencing datasets from human hearts with and without dilated cardiomyopathy (DCM). Chromatin structural gene expression effectively stratified cardiomyocyte and fibroblast populations by disease status. Diseased cardiomyocytes …

Austin Peay State University, January 2025, Tennessee. Comptroller Of The Treasury.

Financial and Compliance Audit Reports

No abstract provided.

Strengthening The Use Of Sexual And Reproductive Health And Rights Evidence In Refugee And Humanitarian Settings, Baobab Research Programme Consortium

Humanitarian Task Force

This guide offers practical, experience-based direction for strengthening the uptake of sexual and reproductive health and rights (SRHR) evidence in refugee and humanitarian settings. Drawing on five years of Baobab’s work in Uganda and Ethiopia, it outlines principles for effective research uptake, including embedded partnerships, rigorous locally owned methods, stakeholder engagement, capacity development, adaptive communication, and continuous learning. The guide illustrates how these approaches enabled pioneering evidence generation—such as the first Humanitarian Violence Against Children Survey (VACS)—and informed service innovations, national policy reforms, and cross-country learning. It provides a replicable framework for translating SRHR research into action and system level …

Cover And Contents

Turkish Journal of Botany

No abstract provided.

Effects Of Hydro- And Nano-Priming Treatments On Seed Germination And Metabolism In Sugar Beet (Beta Vulgaris L.), Sarah Jorjani, Ömer Can Ünüvar, Songül Gürel, Ekrem Gürel

Turkish Journal of Botany

This study examined the effects of hydropriming and nanopriming on the germination and physiological parameters of sugar beet seeds. Seeds were treated with distilled water as a traditional method and with TiO2 nanoparticle solutions at concentrations of 5, 10, and 15 ppm as an advanced method. Seeds were soaked for 3, 6, and 9 h, followed by postpriming maintenance for 10 and 45 days. T he results indicated no statistically significant differences in germination rates between the control and primed groups. Both priming methods markedly increased alpha-amylase activity and chlorophyll content, indicating improved metabolic and photosynthetic potential. Notably, nanopriming for …

Modeling Global Ecological Niche Shifts Of Osyris Spp. Under Climate Change Scenarios: Conservation Priorities For A Threatened Genus, Meng Ting-Yao, Han Shun-Long, He Xiang-Tian, Wu Ya-Ni, Fengjuan Mou

Turkish Journal of Botany

The genus Osyris L. comprises ecologically and economically important evergreen shrubs or small trees, with particular African species currently threatened by unsustainable exploitation. This study projected potential ecological niche shifts for Osyris under four Shared Socioeconomic Pathways (SSPs) using digitized herbarium specimen localities and 20 environmental variables. The genus currently occupies a broad range between 41.32°N–34.85°S latitude and 9.27°W–109.03°E longitude, at elevations from 0 to 3900 m. High-suitability areas cluster primarily in the European-Mediterranean region, eastern/southern Africa, western South America, and Southeast Asia. Projections indicate a significant decline in high-suitability area under all SSP scenarios (SSP126, SSP245, SSP370, SSP585) compared …

2025-2026 Junior Recital - Aidan Quintana (Piano), Aidan Quintana

Junior and Senior Recitals

No abstract provided.

A Novel Strategy Of Mycorrhizal Fungi Usage To Enhance Crop Resilience In Saline Environments: Biopriming With Serendipita Indica, Tuğba Özteki̇n, Meli̇sa Ayişiği, Lale Yildiz Aktaş

Turkish Journal of Botany

Soil salinization is a critical global challenge, threatening agricultural productivity by imposing osmotic stress, ionic toxicity, and oxidative imbalance in plants. This study investigated the potential of Serendipita indica biopriming to enhance salt stress tolerance in maize (Zea mays L. cv. Simon) seedlings through comprehensive physiological and biochemical analyses under controlled conditions. Maize seeds were bioprimed with different concentrations of mycorrhizal fungi S. indica spores and exposed to varying NaCl concentrations (0, 50, 100, and 200 mM). Nonprimed maize seedlings had a gradual reduction in seed vigor index, reaching about 93.56% in 200 mM NaCl treatment. Under nonsaline conditions, S. …

Taxonomic Significance Of Stem And Leaf Anatomy And Pollen And Seed Micromorphological Characters In The Papaver (Poppy) Sect. Rhoeadium From Türkiye, Esengül Özkaymakoğlu, Osman Tugay, Yavuz Bülent Köse, Deni̇z Ulukuş, Bayram Atasagun, Meti̇n Armağan, Ferhat Celep

Turkish Journal of Botany

The poppy (Papaver) has beautiful flowers that attract the attention of not only taxonomists but also the public. However, it also presents several taxonomic problems. This study examines 13 taxa of Papaver sect. Rhoeadium, including the following species native to Türkiye: P. purpureomarginatum, P. dubium subsp. dubium, P. dubium subsp. laevigatum, P. arachnoideum, P. arenarium, P. commutatum subsp. euxinum, P. guerlekense, P. rhopalothece, P. stylatum, P. clavatum, P. syriacum, P. rhoeas, and P. postii. Plant specimens were collected from natural populations, and anatomical investigations were carried out on stem and leaf cross-sections. Pollen and seed features were examined using both …

Complete Genome Characterization Of A New Alphapartitivirus Identified In The Ectomycorrhizal Fungus Lactarius Mediterraneensis, Aigul Kali̇yeva, Ergi̇n Şahi̇n, Gülce Edi̇ş, Ilgaz Akata

Turkish Journal of Botany

Viruses that naturally infect fungi capable of forming mycorrhizal symbioses remain poorly studied. In the present study, a new partitivirus associated with the basidiomycete mycorrhizal fungus Lactarius mediterraneensis was identified and characterized, and it was designated as Lactarius mediterraneensis partitivirus 1 (LmPV1). The complete genome of LmPV1 was determined through high throughput sequencing of double-stranded RNA (dsRNA) extracts and confirmed by Sanger sequencing of RLM-RACE PCR amplicons. T he genome comprises two dsRNA segments, 1899 bp and 1957 bp, each containing a single open reading frame (ORF) a putative RNA-dependent RNA polymerase (RdRp) and a capsid protein (CP). Comparative analysis …

The Indiana Statesman, January 29, 2026, Indiana State University

Student Newspaper

Korean Festival; Rendesvouz at the rec center

Informing Change: A Final Research Report On The Findings From The Longitudinal R&D Partnership For Math Equity Project, H. Colleen Sinclair, Samuel Robison, Youn Kyoung Kim, Stacey R. Terrio, Judith Lee Falgout Rhodes

Reports

This report covers a three-year partnership between the LSU Social Research and Evaluation Center, East Baton Rouge Parish Schools (EBR Schools), and DreamBox Learning, in which we conducted a longitudinal, multi-method examination of the effectiveness of DreamBox’s tech-based math intervention on EBRPS student performance. The three key research questions – developed with guidance from our Gates Foundation funding partners – are outlined below with abbreviated conclusions. The body of the report provides further detail on the methods, results, and interpretations of our quantitative study. We complement these conclusions with qualitative insights drawn from focus groups with teachers and students.

Strategies For Retaining Employees In The Global Healthcare Industry, Tanisha L. Smith

Walden Dissertations and Doctoral Studies

High healthcare employee turnover rates pose a significant threat to organizational productivity, workforce stability, and patient outcomes. Healthcare leaders are concerned with high employee turnover because it contributes to rising operational costs, employee burnout, and a decline in the quality of patient care. Grounded in Herzberg’s two-factor theory of motivation, this qualitative, pragmatic inquiry identified and explored effective strategies that healthcare leaders use to retain employees to maintain organizational productivity and enhance patient outcomes. Data were collected from nine healthcare leaders in the United States using semistructured interviews and publicly available documents. Through thematic analysis with triangulation and member checking …

Leveraging Informatics To Manage Lifelong Monitoring In Childhood Cancer Survivors, Kimberly Davidow, Renee Gresh, E. Anders Kolb, Ellen Guarnieri, Mary R. Cooper

College of Population Health Faculty Papers

Background: Electronic health records (EHR) have long held promise for sharing information efficiently, but this remains challenging. This quality improvement initiative sought to improve the accurate documentation of anthracycline and radiation therapy exposures in pediatric oncology patients who were treated at different institutions through a quality improvement methodology and EHR tools. Methods: A custom-built EHR smartform was previously created. Modifications were made to the smartform, and quality improvement methods were utilized to improve receipt of radiation summaries from other institutions and documentation of chemotherapeutic doses. Results: Three months after interventions, including clinician education and smartform updates, accurate anthracycline documentation improved …

Moore Vs. Primadonna Co., Llc, 142 Nev. Adv. Op. No. 6. (Jan. 29, 2026), Collin Faught

Nevada Supreme Court Summaries

THE COURT HELD THAT A PLAINTIFF INJURED AT A SELF-SERVICE BUSINESS NEED NOT SHOW THE TASK WAS TRADITIONALLY PERFORMED BY EMPLOYEES TO INVOKE MODE-OF-OPERATION LIABILITY.

Usa V. Dajour Naylor

2026 Decisions

USDC for the Western District of Pennsylvania

Relationships Between The Dark Triad And Justification Of Morally Debatable Behaviors In College Students, Emma P. Paulson, Terry F. Pettijohn Ii

Psychology

The present study examined the relationship between Dark Triad personality traits and moral judgments in a sample of 68 undergraduate students recruited from psychology courses at a southeastern university. All participants volunteered through an online system and received course research credit for participation. Participants completed the Short Dark Triad Measure to assess levels of psychopathy, Machiavellianism, and narcissism, as well as the Revised Morally Debatable Behaviors Scale (MDBS-R), in a controlled laboratory setting. Individuals with strong psychopathic traits were predicted to report greater endorsement of morally debatable behaviors. Pearson correlation analyses were conducted to examine associations between Dark Triad traits …

2026-01-29 Guidelines For Tenure Portfolio Manager - 2nd Revisal, Morehead State University. Faculty Senate.

Faculty Senate Records

Second revisal of the Guidelines for Tenure Portfolio Managers presented to the Faculty Senate on January 29, 2026.

2026-01-29 Faculty Senate Meeting Minutes, Morehead State University. Faculty Senate.

Faculty Senate Records

Faculty Senate meeting minutes from January 29, 2026.

Black Hole Spectroscopy And Tests Of General Relativity With Gw250114, The Ligo Scientific Collaboration, The Virgo Collaboration, The Kagra Collaboration

Department of Physics and Astronomy Faculty Scholarship and Creative Works

The binary black hole signal GW250114, the loudest gravitational wave detected to date, offers a unique opportunity to test Einstein’s general relativity (GR) in the high-velocity, strong-gravity regime and probe whether the remnant conforms to the Kerr metric. Upon perturbation, black holes emit a spectrum of damped sinusoids with specific, complex frequencies. Our analysis of the postmerger signal shows that at least two quasinormal modes are required to explain the data, with the most damped remaining statistically significant for about one cycle. We probe the remnant’s Kerr nature by constraining the spectroscopic pattern of the dominant quadrupolar (ℓ =𝑚 =2) …

Retrospective Comparison Of Outcomes Of Osteochondral Allograft Transplantation Of The Knee Using Extended Storage Modality Missouri Osteochondral Preservation System Versus Standard Preservation, Henson Destine, Gaston Davis, Harrison S. Fellheimer, Azra Dees, Nathaniel Kern, Bradford Tucker, Kevin Freedman

Rothman Institute Papers

BACKGROUND: Osteochondral allograft (OCA) transplantation is an established surgical intervention for full-thickness chondral defects. Standard preservation (SP) protocols currently allow for OCAs to be stored for a maximum of 28 days after procurement before significant chondrocyte death. An alternative protocol, the Missouri Osteochondral Allograft Preservation System (MOPS), has been shown to allow for grafts to be stored for twice the maximum time allotment as SP.

PURPOSE: To compare clinical outcomes in patients who have undergone OCA transplantation utilizing the extended storage capabilities of the MOPS versus SP protocols.

STUDY DESIGN: Cohort study; Level of evidence, 3.

METHODS: Patients who underwent …

Partial Versus Full Revision In Cementless Single-Stage Exchange For Hip Periprosthetic Joint Infection: A Multicenter Comparative Study With 10-Year Survivorship Analysis, Wenbo Mu, Atthakorn Jarusriwanna, Boyong Xu, Scot A. Brown, Xiaogang Zhang, Alexander Dawes, Javad Parvizi Md, Li Cao

Rothman Institute Papers

BACKGROUND: Periprosthetic joint infection (PJI) is one of the most challenging complications following total hip arthroplasty (THA). Traditional management typically involves full revision to ensure comprehensive infection eradication. However, for patients with well-fixed implants, partial revision in a single-stage cementless approach may provide a viable alternative, potentially preserving bone stock and reducing operative time. The relative efficacy of this approach compared with full revision remains to be fully explored. This multicenter study aims to determine whether partial revision in cementless single-stage exchange surgery offers comparable infection control outcomes to full revision for select patients with well-fixed implants.

METHODS: We conducted …

Milbank Expands Partnership With The Perlmutter Center For Legal Justice At Cardozo Law, Benjamin N. Cardozo School Of Law

Cardozo Law News Archive

Milbank LLP announced a significant expansion of its partnership with the Perlmutter Center for Legal Justice at Cardozo School of Law, increasing its charitable commitment to $2.5 million through 2029. The expanded funding will strengthen the Milbank Exoneration Review Unit, support additional staffing, and advance post-conviction advocacy for wrongfully convicted and excessively sentenced individuals.

American Democracy Project Spring Kickoff: A New Beginning For Fhsu Library Services And Civic Engagement, Ginger H. Williams, Darrell A. Hamlin, Hsin-Yen Yang

Times Talk Archive & ADP Projects

Join the American Democracy Project Team to ring in the Spring semester and learn about exciting events, programs, and partnerships coming from ADP and our friends at Tebo Library in the months ahead.

Event Details:

• Date: Thursday, January 29, 2026
• Time: 12:00 - 1:00 PM
• Location: Trails Room, MU

(Re)Individualizing Criminal Law, Itay Ravid

Faculty Publications

Criminal law purports to care about the individual culpability of those committing crimes. Individual mental states or defenses based on one’s beliefs are considered foundational to moral responsibility and criminal conviction. The expansion of algorithmic risk assessment tools in the criminal legal system, however, threatens these principles, changing the criminal law subject from an autonomous individual to merely a predicted object. This Article argues that risk assessment tools—now functioning as gatekeepers at both the entry and exit stages of the criminal process, from predictive policing to compassionate release eligibility—have shifted the criminal system away from its foundation in individual culpability. …

The Joy Above All Joys: Roland D. Sawyer’S Socialism For The Working Class, Maggie R. Buglino

Roland D. Sawyer Scholarship Papers

Following the Industrial Revolution, Americans were required to adapt to the nation's new capitalistic society. Witnessing the subsequent struggle of working-class families, 20th century Christian socialist Roland D. Sawyer was resolved to advocate for a reformed economic structure. This paper is dependent entirely on primary sources in the Roland D. Sawyer Collection, available in the University of New Hampshire's Milne Special Collections. Studying Sawyer's autobiography and various socialist writings illustrates his idea of a good life for the American working-class and how they were to achieve it through the adoption of a socialist doctrine. Throughout his activism, he encouraged Americans …

Hormetic Doses Of Lead Metal Ion Stimulated Photosynthetic Attributes In Brassica Juncea  During Various Stages Of Growth, Shalini Dhiman, Arun Dev Singh, Nitika Kapoor, Renu Bhardwaj

Turkish Journal of Botany

Low doses of lead (Pb) ions were used in the present study to investigate their effects on photosynthetic efficiency in Brassica juncea. Plants of B. juncea grown for 30, 45, and 60 days were analysed for root and shoot length, pigment content, gas exchange, chlorophyll fluorescence, primary and secondary metabolites, and nonenzymatic antioxidant responses under exposure to hormetic doses of Pb2+. The findings show that low levels of Pb2+ (especially 18- and 36-µM Pb treatments) improve gas exchange metrics, chlorophyll fluorescence parameters, root and shoot growth, and increased amounts of chlorophyll, carotenoid, xanthophyll and low amounts of pheophytin as compared …

Bibliotech, January 2026, Dr. C.C. And Mable L. Criss Library, University Of Nebraska At Omaha Criss Library

BiblioTech

Criss Libraries' Digital Newsletter, BiblioTech, January 2026 Dr. C.C. and Mabel L. Criss Library, University of Nebraska at Omaha.

The Laura And Isaac Perlmutter Foundation Expands Support For The Perlmutter Center For Legal Justice At Cardozo Law Of Yeshiva University, Bringing Their Total Contribution To $16 Million, With Up To An Additional $2 Million Committed, Benjamin N. Cardozo School Of Law

Cardozo Law News Archive

The Laura and Isaac Perlmutter Foundation announced an additional $500,000 gift to the Perlmutter Center for Legal Justice at Cardozo School of Law, along with a four-year matching commitment of up to $2 million. The expanded support will strengthen the Center's work on wrongful convictions, clemency, resentencing, and experiential legal education while advancing criminal justice reform initiatives.