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2026-01-29 Fep Recommendations (Pac-35), Morehead State University. Faculty Senate.

Faculty Senate Records

Recommendation for FEPs presented to the Faculty Senate on January 29, 2026.

2026-01-29 Faculty Senate Newsletter, Morehead State University. Faculty Senate.

Faculty Senate Records

Faculty Senate newsletter from January 29, 2026.

Dhodh Links Mitochondrial Bioenergetics, One-Carbon Metabolism, And Dna Repair To Sustain Aggressive Prostate Adenocarcinoma, Venugopalareddy Mekala, Jun Hyoung Park, Uttam Rasaily, Vani Venkatappa, Karthik Reddy Kami Reddy, Vasanta Putluri, Kaveri Goel, Sandra L Grimm, Sai Manohar Thota, Taylor Morrison, Cristian Coarfa, Benny Abraham Kaipparettu, Chao Cheng, Nagireddy Putluri, Jeffrey A Jones, Mukesh K Nyati, Michael Ittmann, Natalie R Gassman, Arun Sreekumar

Faculty, Staff and Students Publications

Background

Dihydroorotate dehydrogenase (DHODH) is a mitochondrial enzyme that connects de novo pyrimidine biosynthesis with the electron transport chain (ETC) function. However, its broader role in prostate cancer (PCa) signaling and response to therapy remains unclear.

Methods

We combined transcriptomic, metabolomic, epigenomic, and functional analyses with clinical outcome data to explore the effects of DHODH depletion in ancestry-annotated European American (EA) and African American (AA) prostate cancer cell line models.

Results

DHODH was markedly overexpressed in malignant prostate epithelial cells and was abundant in tumors. Its knockdown hindered cell proliferation by causing pyrimidine depletion, while unexpectedly increasing oxidative phosphorylation, ETC …

Spectator 2026-01-29, Editors Of The Spectator

The Spectator

No abstract provided.

Spartan Daily, January 29, 2026, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2026

Volume 166, Issue 4

A High-Resolution Daily Precipitation Fusion Framework Integrating Radar, Satellite, And Nwp Data Using Machine Learning Over South Korea, Hyoju Park, Hiroyuki Miyazaki, Menas Kafatos, Seung Hee Kim, Yangwon Lee

Institute for ECHO Articles and Research

Accurate precipitation mapping is essential for effective disaster management; however, individual radar, satellite, and numerical weather prediction products often struggle in the topographically complex terrain of South Korea. This study proposes a high-resolution (~500 m) daily precipitation fusion framework that integrates Korea Meteorological Administration (KMA) radar, Global Precipitation Measurement (GPM) Integrated Multi-Satellite Retrievals for GPM (IMERG), and Local Data Assimilation and Prediction System (LDAPS) data. The framework employs a Random Forest model augmented with a monthly Empirical Cumulative Distribution Function (ECDF) correction. Auxiliary predictors are incorporated to enhance physical interpretability and stability, including terrain attributes to represent orographic effects, land-cover …

Artificial Intelligence In Higher Education, Opportunities, And Challenges: A Review, Sharifa Alblooshi

All Works

Artificial intelligence (AI) is a growing force of change in higher education, providing assistance to students, teachers, and administrators in teaching, learning, and administration. As AI technologies advance rapidly, they present a combination of significant opportunities and complex challenges. In this study, we examine the role of AI in higher education, highlighting both its positive and negative impacts, as well as current policy gaps and issues arising from its deployment. The literature on the topic was reviewed to determine how AI decisively impacts teaching and learning, the role of AI in assessments and academic integrity, as well as ethics, psychological …

The Impact Of Ai-Powered Mobile Money System On Supply Chain: Multi-Cases From Smes In The Global South, Mostafa Mohamad, Michael Nii Laryeafio, Ebimoboere Koroye, Derick Nyame, Samuel Ayertey, Adelina Emini

All Works

This study explores the effects of adopting an artificial intelligence (AI)-powered mobile money system (AI-MMS) on supply chain operations among small and medium-sized enter-prises (SMEs) in the Global South. The authors developed a new version of Rogers’ Diffusion of Innovation model (DoI) that considers the geopolitical context and environmental fac-tors, including regulatory framework, trust, risk and complexity, to help understand how AI-MMS can enhance transactional efficiency in SMEs and bridge the financial inclusion gap. Using qualitative methods, we conducted 40 semi-structured interviews with SME owners in Abuja, Lagos, Kaduna, Kano and Port Harcourt and found that AI-MMS enhanced their logistics …

Experience Music Performed Live In The Aeiva Galleries, Feb. 16 At Uab, Shannon Thomason

Browse All News

No abstract provided.

January 29, 2026, James Madison University

The Breeze, 2020-

The Breeze is the student newspaper of James Madison University in Harrisonburg, Virginia.

Geopolitics In The Caribbean: Us Intervention In Puerto Rico And Venezuela, 2025-2026, Latin American And Iberian Institute

LAII Events

Join the LAII, the Department of Anthropology, and the Department of Chicana & Chicano Studies for an informal lunchtime discussion about the current intervention of the US in the Caribbean.

We will explore recent military strikes, regional responses, and broader implications in the continent.

Everyone is welcome! Refreshments will be provided.

Environmental Litigation In The Trumpa Era, Public Interest Law Students Association (Pilsa)

2025–2026 Flyers

Join us for a conversation about the current state of climate litigation in the US.

Seipin Expression In Hepatocytes Impairs The Assembly Of Vldls And Exacerbates Steatohepatitis, Qianqian Dong, Yidan Ma, Xin Chen, Xiaowei Wang, Ziwei Liu, Liwen Qiu, Jin Wu, Yang Liu, Xiaoqin Wu, Yaru Zhou, Mingming Gao, Hongyuan Yang

Faculty, Staff and Student Publications

VLDLs are crucial for maintaining liver and whole-body lipid homeostasis. Limited knowledge exists regarding the lipidation process of VLDL. Endoplasmic reticulum (ER) luminal lipid droplets (LLDs) have been suggested to provide lipids for VLDL lipidation and maturation. Seipin, an integral membrane protein of the ER, plays key roles in the formation of cytoplasmic LDs (CLDs) and adipocyte differentiation. Surprisingly, seipin is hardly detectable in hepatocytes. Given the critical contribution of seipin in forming CLDs, we hypothesize that the absence of seipin in hepatocytes might ensure the proper formation of LLDs and the lipidation and assembly of VLDLs. To explore the …

Downregulation Of Slc40a1 Leads To Iron Accumulation In Fibrotic Lung Fibroblasts, Quanjin Dang, Chaoqun Huang, Yurong Liang, Akshaya Surendran, Dharanya Muthiah, Sankha Hewawasam, Lin Liu

Faculty, Staff and Student Publications

Iron is an essential nutrient for almost all organisms. However, excess iron generates reactive oxygen species and causes tissue injuries. Iron is implicated in idiopathic pulmonary fibrosis (IPF). In this study, we examined iron accumulation in fibrotic lung fibroblasts and the underlying mechanisms. We hypothesize that the downregulation of Solute Carrier Family 40 Member 1 (SLC40A1) results in iron accumulation in lung fibroblasts of IPF patients. Using a Prussian Blue iron staining, we found that iron accumulated in the fibrotic region of the lungs from IPF patients and bleomycin- and asbestos-induced lung fibrosis mice. Iron was partially co-localized with the …

The Origin Of Hepatocellular Carcinoma Depends On Metabolic Zonation, Jason Guo, Roger Liang, Andrew Chung, Zhijie Li, Boyuan Li, Lin Li, Meng-Hsiung Hsieh, Ivy Xiangyi Fang, Benjamin Kroger, Yunguan Wang, Min Zhu, Xiongzhao Ren, Greg Mannino, Yuemeng Jia, Yonglong Wei, Stephen Moore, Daniel J Siegwart, Stephen S Chung, Zixi Wang, Tripti Sharma, Suman Komjeti, Yi Han, Purva Gopal, Guanghua Xiao, Tao Wang, Hao Zhu

Faculty, Staff and Student Publications

The origin of cancer is poorly understood because premalignant cells are rarely followed in their native environments. Although the spatial compartmentalization of metabolic functions is critical for proper liver function, it is unknown whether cancers arise from some zones but not others and whether there are metabolic determinants of cancer risk. Zone-specific, mosaic introduction of Ctnnb1 (catenin beta 1) and Arid2 (AT-rich interaction domain 2) mutations, commonly co-mutated genes in hepatocellular carcinoma (HCC), in mouse models showed that position and metabolic context determine clone fates. Ctnnb1/Arid2-driven cancers were much more likely to arise in zone 3. The …

Trapped And Traumatised: A Scoping Review Of The Psychological Sequelae Of Entrapment Following Motor Vehicle Collision, Thomas A.M. Dixon, Kara Hole, Louise Johnson, Tim Nutbeam

Peninsula Medical School

Background: Motor vehicle collisions (MVCs) are a significant public health challenge, resulting in substantial mortality and morbidity. Entrapment occurs in 12–33% of all MVCs and is associated with greater injury severity, longer on-scene time, and increased mortality. However, the psychological consequences of entrapment remain poorly characterised. Objectives: This scoping review seeks to establish the current understanding of the psychological sequelae of entrapment following MVCs and draws on insights from related fields of study in order to inform future research and clinical practice. Methods: A scoping review was undertaken following established methodological guidance. Searches were completed on NHS Knowledge and Library …

Comparative Outcomes Of Abdominal, Laparoscopic, And Vaginal Sacral Colpopexy: A National Analysis Of Apical Suspension Procedures (2014–2022), Smit Bharat Solanki, Apurva B Pancholy, Vishal Pancholy

Faculty, Staff and Student Publications

Objective: Sacral colpopexy is a well-established procedure for apical suspension, but the relative outcomes of abdominal, laparoscopic, and vaginal approaches remain debated. This study compared perioperative outcomes across these surgical routes using a national database and evaluated trends in robotic assistance.

Materials and methods: We analyzed sacral colpopexy cases from the American College of Surgeons National Surgical Quality Improvement Program between 2014 and 2022. Patient demographics, complication rates, and surgical outcomes were compared among abdominal, laparoscopic, and vaginal procedures. Relative risks (RR) were adjusted for confounders. The utilization of robotic systems in laparoscopic procedures was examined.

Results: Among 61,524 cases, …

Changing Patterns Of Psychotropics Use Among Older Adults With Intellectual Disability Over A Decade, With A Focus On Designated Mental Health Conditions, Rohit Shankar

Peninsula Medical School

ABSTRACTBackground: Psychotropics (sometimes off-label), mental health diagnoses and behaviours of concern are common in olderadults with intellectual disability. Guidelines recommend non-pharmacological interventions and regular medication review.This study examined changes in psychotropics among older adults (≥40) with intellectual disability.Methods: Longitudinal data were obtained from the Intellectual Disability Supplement to the Irish Longitudinal Study onAgeing (IDS-TILDA) at two timepoints [Wave 1(2009/10); Wave 4(2019/20)]. Post hoc analysis, Chi-squared tests and univariatebinary logistic regression were conducted.Results: Overall, psychotropics decreased (59.2% to 56.5%). Significant decreases in antipsychotics (43.1%–40.1%) and sedatives/hypnotics (13.6%–8.1%) and significant increase in antidepressants (26.2%–31.8%) were found. Nearly half of antidepressant usersreported depression …

Black Hole Spectroscopy And Tests Of General Relativity With Gw250114, A. G. Abac, I. Abouelfettouh, Teviet Creighton, Mario C. Diaz, Raul Alberto Espinosa Perez, J. Lawrence, Francisco Llamas Villarreal, Soma Mukherjee, Volker Quetschke, Miriam Ramos Arevalo, Wenhui Wang

Physics & Astronomy Faculty Publications

The binary black hole signal GW250114, the loudest gravitational wave detected to date, offers a unique opportunity to test Einstein’s general relativity (GR) in the high-velocity, strong-gravity regime and probe whether the remnant conforms to the Kerr metric. Upon perturbation, black holes emit a spectrum of damped sinusoids with specific, complex frequencies. Our analysis of the postmerger signal shows that at least two quasinormal modes are required to explain the data, with the most damped remaining statistically significant for about one cycle. We probe the remnant’s Kerr nature by constraining the spectroscopic pattern of the dominant quadrupolar (ℓ =𝑚 =2) …

Enhancing Rn Confidence In Early Recognition And Treatment Of Sepsis, Tiffany Lee Gossai

Walden Dissertations and Doctoral Studies

Background: Sepsis is a leading cause of mortality in U.S. hospitals, with delays in recognition and treatment significantly contributing to poor patient outcomes. Nurses are essential to early identification and timely intervention; however, gaps in confidence and preparedness persist, particularly among newly hired staff. Traditional educational approaches may be insufficient to support rapid clinical recognition and evidence-based management. Purpose: This staff education project evaluated whether participation in a virtual sepsis escape room during general nursing orientation improved newly hired nurses’ confidence in early identification and treatment of sepsis. Methods: A virtual escape room was integrated into an existing general nursing …

Better It Disaster Recovery And Procedures To Improve Response After Computer Crime, Allan Eduardo Arroyo-Melendez

Walden Dissertations and Doctoral Studies

A lack of an effective disaster recovery plan (DRP) can negatively impact business outcomes following a cyberattack. Information technology (IT) managers are concerned that the lack of DRP may increase the risk of ransomware, fines, and public distrust. Grounded in the unified theory of acceptance and use of technology, the purpose of this qualitative pragmatic inquiry study is to explore strategies that some IT managers use to implement a DRP. The participants are four IT managers in the southeast United States. Data were collected through semistructured interviews and a review of publicly available documents. Through thematic analysis, three themes were …

Clinical Practice Guidelines For Suicide Risk Assessment, Jelitta Cleatus

Walden Dissertations and Doctoral Studies

In this doctoral project, I developed a clinical practice guideline (CPG) to address the lack of a standardized suicide risk assessment protocol at a Texas mental health clinic. At project initiation, suicide risk assessment at the facility was inconsistent due to the absence of a CPG. The guideline incorporated the Columbia-Suicide Severity Rating Scale (C-SSRS), a validated instrument that improved early detection of suicidal ideation and behaviors, which were often under recognized in older adults. This inconsistency led to the following clinical question, Does the evidence support the development of a CPG for assessing suicide risk among high-risk patients using …

Investigating Sex Offenders’ Experience Of Being Registered As A Sex Offender, Stacey Mitchell-Swingle

Walden Dissertations and Doctoral Studies

In society, sex offenders are subject to unforeseen consequences of the sex offender registry. The purpose of this qualitative study was to investigate how the sex offender registry contributes to the mental distress of registered sex offenders and their concerns about recidivism. This study addressed a gap in understanding the sex offender registry experiences from the offender’s perspective. The research question addressed how adult male registrants describe their experiences of mental distress associated with registration and how they perceive registration as shaping their risk of reoffending. The theoretical framework was John Braithwaite’s reintegrative shaming theory, with a specific focus on …

Lived Experiences Of Law Enforcement Officers Assigned To Co-Response Teams Responding To Mental Health Crises, Roxanne Miller

Walden Dissertations and Doctoral Studies

Law enforcement officers are increasingly called upon to respond to mental health crises, yet their experiences as members of co-response teams (CRTs) remain underexplored. This study was conducted to address that gap by examining the lived experiences of officers assigned to CRTs that pair specially trained officers with mental health clinicians to respond jointly to calls involving individuals in crisis. The purpose of this qualitative phenomenological study was to describe how officers experience CRT work and how it shapes their perceptions, practices, and professional identity. The study was guided by Lazarus and Folkman’s transactional theory of stress, appraisal, and coping, …

Impact Of Burnout And Empathy On Correctional Officers’ Aggression, Sagan Ladd

Walden Dissertations and Doctoral Studies

Correctional officers experience persistent occupational stress that places them at elevated risk for burnout, which may negatively affect emotional functioning and increase aggression. Guided by general strain theory, this quantitative nonexperimental correlational study examined the relationships between burnout, empathy, and aggression among uniformed correctional officers working in U.S. jails and prisons. Participants (N = 58) completed the Maslach Burnout Inventory, the Interpersonal Reactivity Index, and the Buss–Perry Aggression Questionnaire–Short Form through an anonymous online survey. Simple and multiple linear regression analyses were conducted to answer three research questions. Results indicated that burnout significantly predicted aggression, F(1, 56) = 12.38, p < .001, R² = .18, such that higher burnout was associated with higher aggression scores. Empathy did not significantly predict aggression, F(1, 56) = 2.32, p = .133, R² = .04, though the relationship trended negatively. A multiple regression analysis revealed that burnout and empathy together significantly predicted aggression, F(2, 55) = 7.74, p = .001, R² = .19; however, burnout remained the only significant predictor when controlling for empathy. Additional analyses indicated that burnout significantly predicted all four facets of aggression: verbal aggression, physical aggression, anger, and hostility. These findings suggest that burnout plays a central role in aggression among correctional officers and highlight the importance of organizational and mental health interventions aimed at reducing burnout to promote staff well-being and institutional safety.

Improving Early Detection Of Lung Cancer In Underserved Primary Care Settings, Trent Arden Goode, Ii

Walden Dissertations and Doctoral Studies

Lung cancer is the leading cause of cancer-related mortality in the United States, with underserved populations experiencing higher rates of late-stage diagnosis and preventable death. Despite established screening guidelines, adherence within primary care remains inconsistent, particularly in safety-net settings, reflecting a healthcare administration problem driven by organizational structures and care processes. The purpose of this integrative review was to identify administrative interventions that improve primary care provider adherence to lung cancer screening referral guidelines in safety-net healthcare settings. Guided by the Donabedian Quality Framework, a systematic integrative review was conducted to examine how healthcare structures and processes influence screening implementation. …

Graduates’ Perceptions Of Their High School Career Technical Education Work-Based Learning Experiences, Cheryline M. Hewitt

Walden Dissertations and Doctoral Studies

Little is known about how career and technical education (CTE) work-based learning (WBL) programs support student academic achievement and workforce outcomes. Guided by Kolb’s experiential learning theory, the purpose of this basic qualitative study was to explore high school graduates’ perceptions of their CTE WBL experiences and to identify how completing a CTE WBL program supported and hindered their academic and workforce achievement. Ten graduates of CTE WBL programs were recruited via postsecondary CTE school outreach, Facebook, and LinkedIn groups and participated in a semistructured interview. Thematic analysis using open coding was conducted. The data analysis resulted in three identified …

How Case Management Can Improve Access To Outpatient Mental Health Clinics For Low-Income African American Women, Marie Daphney Vilseant

Walden Dissertations and Doctoral Studies

Abstract: African American women face deeply rooted systemic challenges that affect their access to mental health care treatment. There are no case management techniques that are strategic and equity driven and offer individualized support tailored to the needs of African American women, especially those from low-income backgrounds. The purpose of this study was to explore the role of case management as a potential solution to improve access to outpatient mental health services for this under-served group. The Anderson behavioral model for health care was utilized to understand access and utilization of health care services. The review question focused on case …

The Environmental Mental Health Services Needed For Youth Ages 18-25 Aging Out Of The Foster Care System, Keelin Leger

Walden Dissertations and Doctoral Studies

Youth transitioning out of foster care experience increased mental health challenges that affect their ability to age out successfully to independence. In this qualitative modified action study, the environmental mental health services needed for adolescents, aged 18 to 25, aging out of the foster care system in Lafayette Parish, Louisiana were explored. This study was guided by the Families Rising framework. Purposeful sampling was used to recruit 20 participants who provided insights to this study. Participants were reached by posting flyers on social media and the online platform forums, and they signed the consent form to participate. The data were …

Staff Education On Medication Adherence, Jerome Obiagba

Walden Dissertations and Doctoral Studies

Summary The Doctor of Nursing Practice (DNP) project focuses on improving medication adherence in mental health settings, where many patients do not take medications as prescribed, leading to worsening symptoms, relapse, frequent hospitalizations, higher healthcare costs, and reduced quality of life. This problem mainly affects individuals with anxiety, bipolar disorder, major depressive disorder, and schizophrenia, and is often related to poor understanding of treatment, cultural beliefs, or limited access to care. Because nurses play a key role in medication monitoring, education, and patient support, the project examined whether staff education improves nurses’ knowledge, confidence, and effectiveness compared to standard practice …