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Laser Stimulated Dynamic Thermal Imaging System For Tumor Detection, Hongyu Meng

McKelvey School of Engineering Graduate Student Theses & Dissertations

Laser stimulated dynamic thermal imaging system for tumor detectionby Hongyu Meng Doctor of Philosophy in Biomedical Engineering Washington University in St. Louis, 2021 Professor Samuel Achilefu, Chair Recent advances in infrared sensor technology have enabled the rapid application of thermal imaging in materials science, security and medicine. Relying on the infrared characteristics of living systems, thermal imaging has been used to generate individual heat maps, detect inflammation and tumor. As an imaging system, thermal imaging has the advantages of portability, real-time, non-invasive, and non-contact. But the low specificity of thermal imaging hinders its wide clinical application.

Unfortunately, label-free DTI is …

Improving Resource Efficiency In Cloud Computing, Jiayi Song

McKelvey School of Engineering Graduate Student Theses & Dissertations

Customers inside the cloud computing market are heterogeneous in several aspects, e.g., willingness to pay and performance requirement. By taking advantage of trade-offs created by these heterogeneities, the service provider can realize a more efficient system. This thesis is concerned with methods to improve the utilization of cloud infrastructure resources, and with the role of pricing in realizing those improvements and leveraging heterogeneity. Towards improving utilization, we explore methods to optimize network usage through traffic engineering. Particularly, we introduce a novel optimization framework to decrease the bandwidth required by inter-data center networks through traffic scheduling and shaping, and then propose …

Interfacial Engineering And Photoelectrochemistry Of Patterned Metal/Semiconductor Heterostructures, Che Tan

McKelvey School of Engineering Graduate Student Theses & Dissertations

Photoelectrochemical (PEC) cells enable the conversion of solar energy into storable fuels, which is critical in overcoming the intermittent nature of this largest renewable source. However, the majority of semiconductors used as photoelectrodes in these cells have low conversion efficiencies and/or stabilities. Silicon (Si) is an attractive semiconductor material for photoelectrodes, but the development of efficient Si-based photoanodes is challenging due to their instability in alkaline solutions. Thus, one focus of this dissertation is the design and fabrication of highly stable nickel (Ni)-patterned Si photoanodes through interfacial engineering of the barrier heights. Recently, hot carriers in plasmonic metal nanostructures have …

Anion Exchange Membranes In Electrochemical Energy Systems, Yunzhu Zhang

McKelvey School of Engineering Graduate Student Theses & Dissertations

Non-CO2-emitting sources of renewable energy, such as solar and wind, have become quite popular in recent years, and their electricity generation cost at scale has become comparable with that of gas- and coal-fired power plants. However, their intermittent output makes the resultant electricity hard to dispatch in a reliable manner in the absence of grid-scale electrical energy storage (EES) technologies. Redox-flow batteries (RFBs) are promising devices for medium- to large-scale electric energy storage. They are safe, reliable, and portable, and are designed with decoupled power and energy modules, which makes it easy and cost-effective to scale their output to meet …

Wedding Photographer Loses First Round In Court Challenge To Ny Law, Arthur S. Leonard

Other Publications

No abstract provided.

Abdominal Paraganglioma In A Patient With Fever Of Unknown Origin, Samantha Sokoloff, Barbara Simon

Department of Medicine Faculty Papers

Reaxys Chemistry database information SciVal Topics Funding details

Abstract

Introduction: Paragangliomas have a wide range of clinical presentations. A significant portion of these tumors are discovered as abdominal masses on imaging or palpation in patients without typical symptoms of catecholamine excess [1]. This case reports a 28-year-old female who presented with fever of unknown origin and was found to have an abdominal mass on CT imaging. This mass was biopsied prior to a complete evaluation and confirmed to be a paraganglioma. Case report: We discuss the case of a 28 year-old-female who presented to the Endocrinology office after she was …

Ward Based Goal Directed Fluid Therapy (Gdft) In Acute Pancreatitis (Gap) Trial: A Feasibility Randomised Controlled Trial [Isrctn 36077283], F Froghi, F Soggiu, F Ricciardi, C Vindrola-Padros, L Floros, D Martin, H Filipe, M Varcada, K Gurusamy, S Bhattacharya, A Fanshawe, B Dolcea, P Mathur, B Davidson

Peninsula Medical School

Background: Goal-directed fluid therapy (GDFT) reduces complications in patients undergoing major general surgery. There are no reports of cardiac output evaluation being used to optimise the fluid administration for patients with acute pancreatitis (AP) in a general surgery ward. Method: 50 patients with AP were randomised to either ward-based GDFT (n=25) with intravenous (IV) fluids administered based on stroke volume optimisation protocol or standard care (SC) (n=25), but with blinded cardiac output evaluation, for 48-hours following hospital admission. Primary outcome was feasibility. Results: 50 of 116 eligible patients (43.1%) were recruited over 20 months demonstrating feasibility. 36 (72%) completed the …

P-P06 Ward Based Goal Directed Fluid Therapy (Gdft) In Acute Pancreatitis (Gap) Trial: A Feasibility Randomised Controlled Trial [Isrctn 36077283], F Froghi, F Soggiu, F Ricciardi, C Vindrola-Padros, L Floros, D Martin, H Filipe, M Varcada, K Gurusamy, S Bhattacharya, A Fanshawe, B Dolcea, P Mathur, B Davidson

Peninsula Medical School

No abstract provided.

Political-Pedagogical Character Of The Collective Actions Of The Popular Bars, Magda Victoria Díaz Alzate Sra, Juan Pablo Menjura Acosta Sr, Maria Clara Fonseca Echeverri Sra

The Qualitative Report

Barrismo is a complex phenomenon and cannot be defined universally. Social representation is based on deficient conceptions that relate it to the use of psychoactive substances and violence. This article presents qualitative research evidence based on the epistemological assumptions of social constructionism, a hermeneutical phenomenological design and the use of qualitative interview and documentary and audiovisual review, to understand the political-pedagogical character of the collective actions of the popular bars of the city of Medellín, Colombia, as practices that contribute to the transformation of the territories. Categories found: i. Bars as popular movements: transition from the brave bar to the …

Beach Hazards: Riu Funana, Cape Verde, C Stokes, G Masselink, T Scott, L Brodie

School of Biological and Marine Sciences

No abstract provided.

Dating Martian Mafic Crust; Microstructurally Constrained Baddeleyite Geochronology Of Enriched Shergottites Northwest Africa (Nwa) 7257, Nwa 8679 And Zagami, Lg Staddon, Jr Darling, Wh Schwarz, Nr Stephen, Et Al

School of Geography, Earth and Environmental Sciences

Baddeleyite (monoclinic; m-ZrO2) is a widespread accessory phase within shergottites. However, the effects of shock loading on baddeleyite U-Pb isotopic systematics, and therefore its reliability as a geochronometer within highly shocked lithologies, are less well constrained. To investigate the effects of shock metamorphism on baddeleyite U-Pb chronology, we have conducted high-resolution microstructural analysis and in-situ U-Pb isotopic measurements for baddeleyite within enriched basaltic shergottites Northwest Africa (NWA) 7257, NWA 8679 and Zagami. Electron backscatter diffraction (EBSD) analyses of baddeleyite reveal significant microstructural heterogeneity within individual thin sections, recording widespread partial to complete reversion from high-pressure (≥3.3 GPa) orthorhombic zirconia polymorphs. …

Unordered Cnf Games, Md Lutfar Rahman

Electronic Theses and Dissertations Archive

The classic TQBF problem is to determine who has a winning strategy in a game played on a given CNF formula, where the two players alternate turns picking truth values for the variables in a given order, and the winner is determined by whether the CNF gets satisfied. We study variants of this game in which the variables may be played in any order, and each turn consists of picking a remaining variable and a truth value for it. For the version where the set of variables is partitioned into two halves and each player may only pick variables from …

Epidemiological Studies On Risk Factors Of Chronic Diseases, Rutu Rathod

Electronic Theses and Dissertations Archive

Myocardial Infarction (MI) is one of the most common cardiac conditions in older adults. As the pathophysiological processes underlying human diseases are complex, I utilized all available data to predict the incidence of future MI using exploratory factor analysis. Six factors were identified, each representing a unique risk dimension based on loaded observed variables, e.g., the hemodynamic factor loaded systolic, diastolic blood pressure, and heart rate variables. Four factors (hemodynamic, smoking, blood lipids, and alcohol consumption) were detected as risk factors for future MI. The burden of chronic conditions among children and adolescents is increasing and one of its risk …

Steps Beyond Risk Assessment In Qrm: Rbdm, The Next Horizon, Valerie Mulholland, Anne Greene, Martin J. Lipa

Level 3

The topic of Risk-based Decision Making (RBDM) was highlighted as one of these areas requiring clarification in the International Committee on Harmonisation (ICH) concept paper for the revision of Q9. This paper examines 5 key areas on RBDM identified in the concept paper, focusing on: What good risk-based decision making actually means, How QRM may improve decision-making and How risk-based decisions might be achieved. This was executed by reviewing peer-reviewed published research literature and examining best practices in other industries, with a view to initiating a dialogue which could help advance the questions posed. Based on this analysis, a list …

“Deployment Of Data Analytics To Support Manufacturing At Janssen”, Patrick T. O'Sullivan, Marcus O'Mahony

Level 3

This paper describes two key areas of value that data analytics supported for Janssen: yield optimisation and Tech. Transfer. By focusing on two key business areas the definition of success and scope was clearly understood by all stakeholders from key business leaders to shopfloor operators. Thus, the value of data analytics was apparent. The paper discusses key pitfalls to avoid and identifies two key investments for success.

“Gaining Organisational Acceptance Of A Data Analytics Programme In Eli Lilly”, Anthony Maguire, Marcus O'Mahony

Level 3

This paper describes how Eli Lilly overcame barriers to enable new use of data. This was achieved by adopting a deep understanding of end-user needs and the support of site leaders and end-users to standardise process monitoring. A standard approach of ‘Contexting’, ‘Data-Extraction’, ‘Model build’, ‘On-line Config’, ‘Deploy’, was utilised, using a commercial off-the-shelf software. The paper describes proof of concept demonstrations undertaken and discusses the ingredients to make the journey a success.

“Data Architecture For Pharmaceutical Product Development At Alkermes”, Peter Couture, Damon Warnock, Marcus O'Mahony

Level 3

This paper describes how Alkermes built a data architecture for efficient management of non-GXP and R&D data. Using a ‘Create’, ‘Store’, Describe’ ‘Access’ stepwise model, the ingredients to making the journey a success are described.

“Transitioning Organisations From A Data Quagmire To Knowledge Nirvana Through The Digital Thread”, David Twohig, Barry Heavey

Level 3

Historically, organisations have managed product data in a combination of Microsoft Office, Sharepoint and Document Management Systems. In this paper, we explore how different technologies can be leveraged to create digital product profiles, and in doing so structure data to enable effective knowledge management.

Eliminating Paper-Based Processes During Manufacturing With A Fit-For-Purpose Digital Tool, Andrius Ramanauskas

Level 3

Digital transformation has been a growing priority in the Life Sciences industry, and with Covid it never has been more necessary. This paper presents a technical solution which eliminates paper-based processes during manufacturing with a fit-for-purpose digital tool.

Mechanical Engineering News, Georgia Southern University

Mechanical Engineering: News & Publications (2013-2023)

• Students Awarded Scholarship from Foundry Educational Foundation

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Newsroom (2006-2023)

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Modeling Iterative Reconstruction And Displacement Field In The Large Scale Structure, Atsuhisa Ota, Hee Jong Seo, Shun Saito, Florian Beutler

Physics Faculty Research & Creative Works

The next generation of galaxy surveys like the Dark Energy Spectroscopic Instrument and Euclid will provide datasets orders of magnitude larger than anything available to date. Our ability to model nonlinear effects in late time matter perturbations will be a key to unlock the full potential of these datasets, and the area of initial condition reconstruction is attracting growing attention. Iterative reconstruction developed by Marcel Schmittfull et al. [Phys. Rev. D 96, 023505 (2017)PRVDAQ2470-001010.1103/PhysRevD.96.023505] is a technique designed to reconstruct the displacement field from the observed galaxy distribution. The nonlinear displacement field and initial linear density field are highly correlated. …

Using Characters To Narrow Culture Gaps, Xiangyu Han

Theses

There are a lot of different cultures around the world. It is hard for people with various cultural backgrounds to understand each other. Language is the most direct expression of cultural barriers. With the different structures of languages, communication becomes unsmooth. People can get to know each other better if we narrow down the gaps. The research here discusses the possibility of building a connection between language characters through the graphic. This work will use Chinese and English as an experimental. Images and pictures are the most visual information for people to read. And languages are the most direct information …

Characterization And Proteolytic Maturation Of Head Proteins In A Giant Salmonella Virus, Aaron Scheuch

Theses

Giant phages are of interest for biocontrol of pathogenic bacteria, however, there is limited knowledge about their biology. We study the Salmonella phage SPN3US to better understand virion structure and function. SPN3US has a contractile tail and a large T=27 icosahedral capsid that contains its 240-kb genome. Previous analyses showed the SPN3US virion is highly unusual because it contains >80 different proteins, a number that is highly unusual for a tailed phage. In addition, there is a mass (>40 MDa) of proteins ("ejection proteins") within the head that enter the Salmonella cell, possibly with roles in host takeover at …

The Artemis Project: Exploring Mass Communication Utilizing A Visual Exploration Of Influential Imagery., Brooke K. Collins

Theses

Society struggles to have difficult conversations. Polite silence is often preferred to dredging up uncomfortable topics. This silence is deafening as the majority of Americans do not consider topics such as The American Sex Trafficking Crisis. In a post-pandemic world, how do we initiate difficult conversations in both digital forums and public domains? The Artemis Project seeks to visually explore this gap in conversation, undergoing an optical investigation of utilizing design and illustrative practices as tools for mass communication. This project conceptualizes the development and application of imagery to introduce a conversation, facilitating understanding and empathy. In short, The Artemis …

Esaal (Smart Delivery System In Dubai), Banout Alketbi

Theses

Delivery sector has been facing many issues lately due to covid 19 pandemic mainly delivering items and packages late and some of them being in bad condition. The new smart delivery system ( will help in making the delivery system in Dubai more sustainable and at the same time more accurately functioning The proposed system will achieve that by running on their own tracks that are especially made for them to deliver Furthermore, the new designed system will be running and functioning depe nding on solar energy. These routes will be designed to have way to all of the areas …

Amazon Reviews Using Sentiment Analysis, Ammar Rashed Hamdallah

Theses

The intense competition to attract and maintain customers online is compelling businesses to implement novel strategies to enhance the customer experiences. It is becoming necessary for companies to examine customer reviews on online platforms such as Amazon to understand better how customers rate their products and services. The purpose of this study is to investigate how companies can conduct sentiment analysis based on Amazon reviews to gain more insights into customer experiences. The dataset selected for this capstone consists of customer reviews and ratings from consumer reviews of Amazon products. Amazon product reviews enable a business to gain insights on …

Calculating Common Vulnerability Scoring System’S Environmental Metrics Using Context-Aware Network Graphs, Christopher Thomas Enoch

Theses

Software vulnerabilities have significant costs associated with them. To aid in the prioritization of vulnerabilities, analysts often utilize Common Vulnerability Scoring System’s Base severity scores. However, the Base scores provided from the National Vulnerability Database are subjective and may incorrectly convey the severity of the vulnerability in an organization's network. This thesis proposes a method to statically analyze context-aware network graphs to increase accuracy of CVSS severity scores. Through experimentation of the proposed methodology, it is determined that context-aware network graphs can capture the required metrics to generate modified severity scores. The proposed approach has some accuracy to it, but …

Analyzing The Arguments And Opinions Surrounding Space Privatization, Henry Yaeger

Theses

As space exploration technology advances and more private actors engage in independent space activities, national governments and international organizations need to reform and modernize their approach to regulating private space activities in order to better capture and distribute the benefits of those activities. This paper examines several disparate suggestions and ideas found in 38 articles ranging from current space policy literate to international treaties in order to generate four possible policy approaches to private space activities: the Status Quo, Self-Regulation, New International Treaties and Expanded Public-Private Partnership models. It then compares and contrasts these four alternatives to determine which can …