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Gaze, Volume 10, Number 8

Gaze, 1979-1990

Co-Editors: Allen Cook, John Stilwell. Staff Writers: Bob Dumais, Susan McKenzie, Vincent Astor, Ken Horton, Becky Caperton. Typesetting and Layout: Allen Cook, Bob Dumais, John Stilwell, Vincent Astor. Circulation: Cecil McLeod, John Stilwell, Bob Dumais. Advertising: Bob Dumais, Vincent Astor.

This is the second of two issues printed as volume 10, number 8.

Special thanks to Rhodes College and the Paul Barret Jr. Library for providing initial scanning of this collection.

The Measuring Of Assortativeness In Marriage, Pierre-André Chiappori, Monica Costa-Dias, Costas Meghir

Cowles Foundation Discussion Papers

Measuring the extent to which assortative matching
differs between two economies is challenging when the marginal distributions of the characteristic along which sorting takes place (e.g. education) also changes for either or both sexes. Drawing from the statistics literature we define simple conditions that any index has to satisfy to provide a measure of change in sorting that is not distorted by changes in the marginal distributions of the characteristic. While our characterisation of indices of assortativeness is not complete, and hence cannot exclude the possibility of multiple indices providing contradictory results, in an empirical application to US data we …

A Multi-Site Analysis Of The Prevalence Of Food Insecurity In The United States, Before And During The Covid-19 Pandemic, Meredith T. Niles, Alyssa W. Beavers, Lauren A. Clay, Marcelle M. Dougan, Giselle A. Pignotti, Stephanie Rogus, Mateja R. Savoie-Roskos, Rachel E. Schattman, Rachel M. Zack, Francesco Acciai, Deanne Allegro, Emily H. Belarmino, Farryl Bertmann, Erin Biehl, Nick Birk, Jessica Bishop-Royse, Christine Bozlak, For Full Author List, See Comments Below

Faculty Research, Scholarly, and Creative Activity

Background: The coronavirus disease 2019 (COVID-19) pandemic profoundly affected food systems including food security. Understanding how the COVID-19 pandemic impacted food security is important to provide support and identify long-term impacts and needs. Objective: The National Food Access and COVID research Team (NFACT) was formed to assess food security over different US study sites throughout the pandemic, using common instruments and measurements. This study presents results from 18 study sites across 15 states and nationally over the first year of the COVID-19 pandemic. Methods: A validated survey instrument was developed and implemented in whole or part through an online survey …

The Weaker Sex: Male Lingcod (Ophiodon Elongatus) With Blue Color Polymorphism Are More Burdened By Parasites Than Are Other Sex–Color Combinations, Chelsea L. Wood, Katie L. Leslie, Alanna Greene, Laurel S. Lam, Bonnie Basnett, Scott L. Hamilton, Jameal F. Samhouri

Faculty Research, Scholarly, and Creative Activity

The unusual blue color polymorphism of lingcod (Ophiodon elongatus) is the subject of much speculation but little empirical research; ~20% of lingcod individuals exhibit this striking blue color morph, which is discrete from and found within the same populations as the more common brown morph. In other species, color polymorphisms are intimately linked with host–parasite interactions, which led us to ask whether blue coloration in lingcod might be associated with parasitism, either as cause or effect. To test how color and parasitism are related in this host species, we performed parasitological dissection of 89 lingcod individuals collected across more than …

Anti-Inflammatory Activity Of Four Triterpenoids Isolated From Poriae Cutis, Lijia Zhang, Mengzhou Yin, Xi Feng, Salam A. Ibrahim, Ying Liu, Wen Huang

Faculty Research, Scholarly, and Creative Activity

In this study, triterpenoid compounds from Poriae Cutis were separated by high-speed countercurrent chromatography (HSCCC) and identified using ultra-high performance liquid chromatography quadrupole time-of-flight tandem mass spectrometry (UHPLC-QTOF-MS/MS) and nuclear magnetic resonance (NMR). The in vitro anti-inflammatory activities of the purified triterpenoids on RAW 264.7 cells were also investigated. Triterpenoids, poricoic acid B, poricoic acid A, dehydrotrametenolic acid, and dehydroeburicoic acid were obtained; their levels of purity were 90%, 92%, 93%, and 96%, respectively. The results indicated that poricoic acid B had higher anti-inflammatory activity than those of poricoic acid A by inhibiting the generation of NO in lipopolysaccharide (LPS)-induced …

Korean Learners’ Acquisition And Use Of Variable First-Person Subject Forms In Spanish, Avizia Y. Long

Faculty Research, Scholarly, and Creative Activity

Within the scope of research that lies at the intersection of sociolinguistics and second language acquisition, there is a growing body of empirical work on learners’ acquisition of variable subject expression in Spanish. This research has been instrumental for demonstrating that second language (L2) learners acquire linguistic and social constraints on subject form use. The present study extends research on variable Spanish subject expression to an understudied learner population: native Korean-speaking learners. Interview data were examined for the range and frequency of first-person subject forms produced by Korean-speaking learners at four instructional levels as well as linguistic and individual (extralinguistic) …

The Future Is Big - And Small: Remote Sensing Enables Cross- Scale Comparisons Of Microbiome Dynamics And Ecological Consequences, Deanna S. Beatty, Lillian R. Aoki, Olivia J. Graham, Bo Yang

Faculty Research, Scholarly, and Creative Activity

Coupling remote sensing with microbial omics-based approaches provides a promising new frontier for scientists to scale microbial interactions across space and time. These data-rich, interdisciplinary methods allow us to better understand interactions between microbial communities and their environments and, in turn, their impact on ecosystem structure and function. Here, we highlight current and novel examples of applying remote sensing, machine learning, spatial statistics, and omics data approaches to marine, aquatic, and terrestrial systems. We emphasize the importance of integrating biochemical and spatiotemporal environmental data to move toward a predictive framework of microbiome interactions and their ecosystemlevel effects. Finally, we emphasize …

Head-Mounted Accelerometry Accurately Detects Prey Capture In California Sea Lions, Mason R. Cole, Jenifer A. Zeligs, Stefani Skrovan, Birgitte I. Mcdonald

Faculty Research, Scholarly, and Creative Activity

Detecting when and where animals feed is key to understanding their ecophysiology, but our ability to collect these data in marine mammals remains limited. Here, we test a tag-based accelerometry method to detect prey capture in California sea lions. From synchronized underwater video and acceleration data of two trained sea lions, we isolated a combined acceleration and Jerk pattern that reliably indicated prey capture in training datasets. We observed a stereotyped feeding motion in underwater video that included (1) mouth opening while approaching prey; (2) head deceleration to allow initial suction or prey engulfment, and (3) jaw closure. This motion …

Deep Underground Neutrino Experiment (Dune) Near Detector Conceptual Design Report, A. Abed Abud, B. Abi, R. Acciarri, M. A. Acero, G. Adamov, D. Adams, M. Adinolfi, A. Aduszkiewicz, Z. Ahmad, J. Ahmed, T. Alion, S. Alonso Monsalve, M. Alrashed, C. Alt, A. Alton, P. Amedo, A. Hatzikoutelis, For Full Author List, See Comments Below

Faculty Research, Scholarly, and Creative Activity

The Deep Underground Neutrino Experiment (DUNE) is an international, world-class experiment aimed at exploring fundamental questions about the universe that are at the forefront of astrophysics and particle physics research. DUNE will study questions pertaining to the preponderance of matter over antimatter in the early universe, the dynamics of supernovae, the subtleties of neutrino interaction physics, and a number of beyond the Standard Model topics accessible in a powerful neutrino beam. A critical component of the DUNE physics program involves the study of changes in a powerful beam of neutrinos, i.e., neutrino oscillations, as the neutrinos propagate a long distance. …

The Extracellular Contractile Injection System Is Enriched In Environmental Microbes And Associates With Numerous Toxins, Alexander Martin Geller, Inbal Pollin, David Zlotkin, Aleks Danov, Nimrod Nachmias, William B. Andreopoulos, Keren Shemesh, Asaf Levy

Faculty Research, Scholarly, and Creative Activity

The extracellular Contractile Injection System (eCIS) is a toxin-delivery particle that evolved from a bacteriophage tail. Four eCISs have previously been shown to mediate interactions between bacteria and their invertebrate hosts. Here, we identify eCIS loci in 1,249 bacterial and archaeal genomes and reveal an enrichment of these loci in environmental microbes and their apparent absence from mammalian pathogens. We show that 13 eCIS-associated toxin genes from diverse microbes can inhibit the growth of bacteria and/or yeast. We identify immunity genes that protect bacteria from self-intoxication, further supporting an antibacterial role for some eCISs. We also identify previously undescribed eCIS …

Community Norms Of The Muscle Dysmorphic Disorder Inventory (Mddi) Among Cisgender Sexual Minority Men And Women, Jason M. Nagata, Emilio J. Compte, Chloe J. Cattle, Jason M. Lavender, Tiffany A. Brown, Stuart B. Murray, Annesa Flentje, Matthew R. Capriotti, Micah E. Lubensky, Juno Obedin-Maliver, Mitchell R. Lunn

Faculty Research, Scholarly, and Creative Activity

Background: Representing the pathological extreme pursuit of muscularity, muscle dysmorphia (MD) is characterized by a pervasive belief or fear around insufficient muscularity and an elevated drive for muscularity. Despite evidence of elevated body image-related concerns among sexual minority populations, little is known about the degree of muscle dysmorphia (MD) symptoms among sexual minorities, particularly based on Muscle Dysmorphic Disorder Inventory (MDDI) scores. The objective of this study was to examine the nature and severity of MD symptoms in cisgender sexual minority men and women and provide community norms of the MDDI for these populations. Methods: Data from participants in The …

Species And Population Specific Gene Expression In Blood Transcriptomes Of Marine Turtles, Shreya M. Banerjee, Jamie Adkins Stoll, Camryn D. Allen, Jennifer M. Lynch, Heather S. Harris, Lauren Kenyon, Richard E. Connon, Eleanor J. Sterling, Eugenia Naro-Maciel, Kathryn Mcfadden, Margaret M. Lamont, James Benge, Nadia B. Fernandez, Jeffrey A. Seminoff, Scott R. Benson, Rebecca L. Lewison, Tomoharu Eguchi, For Full Author List, See Comments Below

Faculty Research, Scholarly, and Creative Activity

Background: Transcriptomic data has demonstrated utility to advance the study of physiological diversity and organisms’ responses to environmental stressors. However, a lack of genomic resources and challenges associated with collecting high-quality RNA can limit its application for many wild populations. Minimally invasive blood sampling combined with de novo transcriptomic approaches has great potential to alleviate these barriers. Here, we advance these goals for marine turtles by generating high quality de novo blood transcriptome assemblies to characterize functional diversity and compare global transcriptional profiles between tissues, species, and foraging aggregations. Results: We generated high quality blood transcriptome assemblies for hawksbill (Eretmochelys …

Hidden Markov Models Identify Major Movement Modes In Accelerometer And Magnetometer Data From Four Albatross Species, Melinda G. Conners, Théo Michelot, Eleanor I. Heywood, Rachael A. Orben, Richard A. Phillips, Alexei L. Vyssotski, Scott A. Shaffer, Lesley H. Thorne

Faculty Research, Scholarly, and Creative Activity

Background: Inertial measurement units (IMUs) with high-resolution sensors such as accelerometers are now used extensively to study fine-scale behavior in a wide range of marine and terrestrial animals. Robust and practical methods are required for the computationally-demanding analysis of the resulting large datasets, particularly for automating classification routines that construct behavioral time series and time-activity budgets. Magnetometers are used increasingly to study behavior, but it is not clear how these sensors contribute to the accuracy of behavioral classification methods. Development of effective classification methodology is key to understanding energetic and life-history implications of foraging and other behaviors. Methods: We deployed …

Potential Health And Economic Impacts Of Dexamethasone Treatment For Patients With Covid-19, Ricardo Águas, Adam Mahdi, Rima Shretta, Peter Horby, Martin Landray, Lisa White, Fatima Arifi, Chynar Zhumalieva, Inke N.D. Lubis, Antoninho Benjamin Monteiro, Ainura Moldokmatova, Siyu Chen, Aida Estebesova, Mofakhar Hussain, Dipti Lata, Emmanuel A. Bakare, Michael Klein, For Full Author List, See Comments Below

Faculty Research, Scholarly, and Creative Activity

Dexamethasone can reduce mortality in hospitalised COVID-19 patients needing oxygen and ventilation by 18% and 36%, respectively. Here, we estimate the potential number of lives saved and life years gained if this treatment were to be rolled out in the UK and globally, as well as the cost-effectiveness of implementing this intervention. Assuming SARS-CoV-2 exposure levels of 5% to 15%, we estimate that, for the UK, approximately 12,000 (4,250 - 27,000) lives could be saved between July and December 2020. Assuming that dexamethasone has a similar effect size in settings where access to oxygen therapies is limited, this would translate …

Impact Of The Who Surgical Safety Checklist Relative To Its Design And Intended Use: A Systematic Review And Meta-Meta-Analysis, Kenji T. Sotto, Barbara K. Burian, Mary E. Brindle

Faculty Research, Scholarly, and Creative Activity

Background
The aim of this study was to identify what parts of the World Health Organization Surgical Safety Checklist (WHO SSC) are working, what can be done to make it more effective, and to determine if it achieved its intended effect relative to its design and intended use.
Study Design
We conducted a qualitative thematic analysis and meta-meta-analyses of findings in WHO SSC systematic reviews following Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines.
Results
Twenty systematic reviews were included for qualitative thematic analysis. Narrative information was coded in 4 primary areas with a focus on impact of …

The Invisible Language: Unintentional Patronage And Missions Practice In Contemporary Thailand, Samuel Burton Jones

Electronic Theses and Dissertations

Patronage-clientelism is a current and important topic of discussion among the anthropological and missiological community. The effects of unintended patronage by Western missionaries in the context of Thai culture, however, are underexplored in academic research. In this study, I analyzed the effects of unintentional patronage among Western missionaries in a Thai cross-cultural ministry context. To do this I utilized a multiple case study method in which I compared four cases and analyzed for examples of how unintentional patronage is generated. I discovered that unintentional patronage was likely a result of insufficient missionary education regarding patronage-clientelism, as well as a lack …

The Impact Of Leadership And Institutional Priorities On Degree Completion Of Community College Students, Estelle L. Garza

Electronic Theses and Dissertations

This study explored student perceptions of leadership and the impact they believed it to have on their ability to complete a degree at a community college district. Community college degree completion is both a statewide and national problem as most students who start a degree program will drop out before reaching the requirements to finish their degree, which can hurt their career opportunities and the economy. The purpose of this study was to determine how students perceive factors like leadership and their satisfaction with institutional priority factors to impact degree completion. This study used action research and a mixed methods …

The Human Right To Water And Sanitation: Using Natural Language Processing To Uncover Patterns In Academic Publishing, Christopher Michael Faulkner, Joshua Earl Lambert, Bruce M. Wilson, Matthew Steven Faulkner

Faculty Research, Scholarly, and Creative Activity

After years of advocacy and international negotiation, the General Assembly of the United Nations voted to officially recognize a stand-alone human right to water and sanitation on 28 July 2010. Since, academic scholarship has continued to grow in an effort to understand the implications of the codification of this human right. Yet, with this growth, it has become impractical if not impossible for scholars to keep up with the advancement of academic knowledge or to make sense of it in a systematic way. In short, to date, we know very little about the trends in the literature as they have …

Punnett Squares Or Protein Production? The Expert–Novice Divide For Conceptions Of Genes And Gene Expression, Dina L. Newman, Aeowynn Coakley, Aidan Link, Korinne Mills, L. Kate Wright

Faculty Research, Scholarly, and Creative Activity

Concepts of molecular biology and genetics are difficult for many biology undergraduate students to master yet are crucial for deep understanding of how life works. By asking students to draw their ideas, we attempted to uncover the mental models about genes and gene expression held by biology students (n = 23) and experts (n = 18) using semistructured interviews. A large divide was identified between novice and expert conceptions. While experts typically drew box-and-line representations and thought about genes as regions of DNA that were used to encode products, students typically drew whole chromosomes rather than focusing on gene structure …

Drivers Of Understory Plant Communities In Sierra Nevada Mixed Conifer Forests With Pyrodiversity, Kate Wilkin, Lauren Ponisio, Danny L. Fry, Brandon M. Collins, Tadashi Moody, Scott L. Stephens

Faculty Research, Scholarly, and Creative Activity

Background: Fire suppression in western North America increased and homogenized overstory cover in conifer forests, which likely affected understory plant communities. We sought to characterize understory plant communities and their drivers using plot-based observations from two contemporary reference sites in the Sierra Nevada, USA. These sites had long-established natural fire programs, which have resulted in restored natural fire regimes. In this study, we investigated how pyrodiversity—the diversity of fire size, severity, season, and frequency—and other environment factors influenced species composition and cover of forest understory plant communities. Results: Understory plant communities were influenced by a combination of environmental, plot-scale recent …

Immunological And Hematological Outcomes Following Protracted Low Dose/Low Dose Rate Ionizing Radiation And Simulated Microgravity, Amber M. Paul, Eliah G. Overbey, Willian A. Da Silveira, Nathaniel Szewczyk, Nina C. Nishiyama, Michael J. Pecaut, Sulekha Anand, Jonathan M. Galazka, Xiao Wen Mao

Faculty Research, Scholarly, and Creative Activity

Using a ground-based model to simulate spaceflight [21-days of single-housed, hindlimb unloading (HLU) combined with continuous low-dose gamma irradiation (LDR, total dose of 0.04 Gy)], an in-depth survey of the immune and hematological systems of mice at 7-days post-exposure was performed. Collected blood was profiled with a hematology analyzer and spleens were analyzed by whole transcriptome shotgun sequencing (RNA-sequencing). The results revealed negligible differences in immune differentials. However, hematological system analyses of whole blood indicated large disparities in red blood cell differentials and morphology, suggestive of anemia. Murine Reactome networks indicated majority of spleen cells displayed differentially expressed genes (DEG) …

Adaptive Laboratory Evolution Of Β-Caryophyllene Producing Saccharomyces Cerevisiae, Avinash Godara, Katy C. Kao

Faculty Research, Scholarly, and Creative Activity

Background: β-Caryophyllene is a plant terpenoid with therapeutic and biofuel properties. Production of terpenoids through microbial cells is a potentially sustainable alternative for production. Adaptive laboratory evolution is a complementary technique to metabolic engineering for strain improvement, if the product-of-interest is coupled with growth. Here we use a combination of pathway engineering and adaptive laboratory evolution to improve the production of β-caryophyllene, an extracellular product, by leveraging the antioxidant potential of the compound. Results: Using oxidative stress as selective pressure, we developed an adaptive laboratory evolution that worked to evolve an engineered β-caryophyllene producing yeast strain for improved production within …

Fuel Load, Stand Structure, And Understory Species Composition Following Prescribed Fire In An Old-Growth Coast Redwood (Sequoia Sempervirens) Forest, David Cowman, Will Russell

Faculty Research, Scholarly, and Creative Activity

Background: With the prevalence of catastrophic wildfire increasing in response to widespread fire suppression and climate change, land managers have sought methods to increase the resiliency of landscapes to fire. The application of prescribed burning in ecosystems adapted to fire can reduce fuel load and fire potential while minimizing impacts to the ecosystem as a whole. Coast redwood forests have historically experienced fire from both natural and anthropogenic sources, and are likely to respond favorably to its reintroduction. Results: Random sampling was conducted in three burned sites and in three unburned sites, in an old-growth coast redwood (Sequoia sempervirens [D. …

Identification And Characterization Of Bisbenzimide Compounds That Inhibit Human Cytomegalovirus Replication, Nicole Falci Finardi, Hyeongjun Kim, Lee Z. Hernandez, Matthew R. G. Russell, Catherine M-K Ho, Vattipally B. Sreenu, Hannah A. Wenham, Andy Merritt, Blair L. Strang

Physics & Astronomy Faculty Publications

The shortcomings of current anti-human cytomegalovirus (HCMV) drugs has stimulated a search for anti-HCMV compounds with novel targets. We screened collections of bioactive compounds and identified a range of compounds with the potential to inhibit HCMV replication. Of these compounds, we selected bisbenzimide compound RO-90-7501 for further study. We generated analogues of RO-90-7501 and found that one compound, MRT00210423, had increased anti-HCMV activity compared to RO-90-7501. Using a combination of compound analogues, microscopy and biochemical assays we found RO-90-7501 and MRT00210423 interacted with DNA. In single molecule microscopy experiments we found RO-90-7501, but not MRT00210423, was able to compact DNA, …

Identification And Characterization Of Bisbenzimide Compounds That Inhibit Human Cytomegalovirus Replication, Nicole Falci Finardi, Hyeongjun Kim, Lee Z. Hernandez, Matthew R. G. Russell, Catherine M-K Ho, Vattipally B. Sreenu, Hannah A. Wenham, Andy Merritt, Blair L. Strang

Physics & Astronomy Faculty Publications

The shortcomings of current anti-human cytomegalovirus (HCMV) drugs has stimulated a search for anti-HCMV compounds with novel targets. We screened collections of bioactive compounds and identified a range of compounds with the potential to inhibit HCMV replication. Of these compounds, we selected bisbenzimide compound RO-90-7501 for further study. We generated analogues of RO-90-7501 and found that one compound, MRT00210423, had increased anti-HCMV activity compared to RO-90-7501. Using a combination of compound analogues, microscopy and biochemical assays we found RO-90-7501 and MRT00210423 interacted with DNA. In single molecule microscopy experiments we found RO-90-7501, but not MRT00210423, was able to compact DNA, …

How Should Medical Schools Foster Equity And Inclusion In Admissions?, Adela Valdez, Lala Forrest, Alessandra Jimenez, Kim-Thu Pham

School of Medicine Publications

This commentary in response to a case considers how merit and features of medical school applicants’ dossiers should be drawn upon in admissions processes to promote equity and inclusion in medicine. It is argued that medical schools should incentivize inclusion by redefining merit in their admissions goals and processes, promote meaningful inclusion, and show institutional leadership in addressing social justice.

The Landscape Of Renal Replacement Therapy In Veterans Affairs Medical Center Intensive Care Units, Chandan Vangala, Maulin Shah, Natasha N Dave, Layth Al Attar, Sankar D Navaneethan, Venkat Ramanathan, Susan Crowley, Wolfgang C Winkelmayer

Faculty, Staff and Students Publications

BACKGROUND: Outpatient dialysis is standardized with several evidence-based measures of adequacy and quality that providers aim to meet while providing treatment. By contrast, in the intensive care unit (ICU) there are different types of prolonged and continuous renal replacement therapies (PIRRT and CRRT, respectively) with varied strategies for addressing patient care and a dearth of nationally accepted quality parameters. To eventually describe appropriate quality measures for ICU-related renal replacement therapy (RRT), we first aimed to capture the variety and prevalence of basic strategies and equipment utilized in the ICUs of Veteran Affairs (VA) medical facilities with inpatient hemodialysis capabilities.

METHODS: …

The Bridwell Quill. Issues 39-40: The Mystic & The Muse, Anthony Elia

Bridwell Library Publications

No abstract provided.

Combined Amplification And Sound Therapy For Individuals With Tinnitus And Coexisting Hearing Loss: A Retrospective Cohort Study, Purushothaman Ganesan, Hansapani Rodrigo, Jason Schmiedge, Rob Reiter, Simham Swapna, Vinaya Manchaiah

School of Mathematical & Statistical Sciences Faculty Publications

BACKGROUND: The heterogeneity of tinnitus perception and its impact necessitates a tailor-made management approach in everyone. The current study examined the effects of residual inhibition in combined amplification and sound therapy in individuals with tinnitus and coexisting hearing loss.

METHODS: A retrospective analysis was performed on patients with tinnitus and coexisting hearing loss between 2016 and 2019. A total of 72 patients provided with combined amplification and sound therapy were divided into 3 groups based on residual inhibition: (i) complete residual inhibition, (ii) partial residual inhibition, and (iii) negative residual inhibition. Tinnitus severity was measured using the Tinnitus …

The Sun In Its Glory: The Diffusion Of Jonathan Dymond’S Works In The United States, 1831-1836, Jennifer Rycenga

Faculty Research, Scholarly, and Creative Activity

The English Quaker and linen-draper Jonathan Dymond (1796-1828) is best known for his strong philosophic articulation of the testimony against war. The first American edition of Dymond’s work, though, was published not by Quakers but by a small group of activist-thinkers in north-eastern Connecticut, the Windham County Peace Society, which issued a thousand copies of Dymond’s The Applicability of the Pacific Principles of the New Testament to the Conduct of States in the spring of 1832. Dymond’s systematic moral philosophy extended into many corners of the burgeoning philanthropic movements in New England, most notably among Immediate Abolitionists, within the Peace …