Digital Commons Network^™

Population Connectivity In Voles (Microtus Sp.) As A Gauge For Tall Grass Prairie Restoration In Midwestern North America, Marlis R. Douglas, Steven M. Mussmann, Tyler Chafin, Whitney J.B. Anthonysamy, Mark A. Davis, Matthew P. Mulligan, Robert L. Schooley, Wade Louis, Michael E. Douglas

Biological Sciences Faculty Publications and Presentations

Ecological restoration can promote biodiversity conservation in anthropogenically fragmented habitats, but effectiveness of these management efforts need to be statistically validated to determine ’success.’ One such approach is to gauge the extent of recolonization as a measure of landscape permeability and, in turn, population connectivity. In this context, we estimated dispersal and population connectivity in prairie vole (Microtus ochrogaster; N = 231) and meadow vole (M. pennsylvanicus; N = 83) within five tall-grass prairie restoration sites embedded within the agricultural matrix of midwestern North America. We predicted that vole dispersal would be constrained by the …

Cnidarian Hair Cell Development Illuminates An Ancient Role For The Class Iv Pou Transcription Factor In Defining Mechanoreceptor Identity, Ethan Ozment, Arianna N. Tamvacakis, Jianhong Zhou, Pablo Yamild Rosiles-Loeza, Estaban Elias Escobar-Hernandez, Selene L. Fernandez-Valverde, Nagayasu Nakanishi

Biological Sciences Faculty Publications and Presentations

Although specialized mechanosensory cells are found across animal phylogeny, early evolutionary histories of mechanoreceptor development remain enigmatic. Cnidaria (e.g. sea anemones and jellyfishes) is the sister group to well-studied Bilateria (e.g. flies and vertebrates), and has two mechanosensory cell types - a lineage-specific sensory effector known as the cnidocyte, and a classical mechanosensory neuron referred to as the hair cell. While developmental genetics of cnidocytes is increasingly understood, genes essential for cnidarian hair cell development are unknown. Here, we show that the class IV POU homeodomain transcription factor (POU-IV) - an indispensable regulator of mechanosensory cell differentiation in Bilateria and …

Ogden Type I To Iii Tibial Tubercle Fractures In Skeletally Immature Patients: Is Routine Anterior Compartment Fasciotomy Of The Leg Indicated?, Corey Brown, Brian A. Kelly, Kirsten Brouillet, Scott J. Luhmann

2020-Current year OA Pubs

PURPOSE: Determine the frequency of compartment syndrome of the leg after displaced, operatively treated modified Ogden I to III tibial tubercle fractures (TTFxs), evaluate the preoperative assessment and use of advanced imaging, and need for prophylactic fasciotomies.

METHODS: Retrospective analysis of operatively treated, displaced modified Ogden I to III TTFxs, at our level 1 paediatric trauma centre between 2007 and 2019. Modified Ogden Type IV and V fracture patterns were excluded. Fracture patterns were determined by plain radiographs.

RESULTS: There were 49 modified Ogden I to III TTFxs in 48 patients. None had signs nor symptoms of vascular compromise, compartment …

Development Of A Qualified Clinical Data Registry For Emergency Medicine, Stephen K Epstein, Richard T Griffey, Michelle P Lin, James J Augustine, Pawan Goyal, Arjun K Venkatesh

2020-Current year OA Pubs

The passage of the Medicare Access and CHIP Reauthorization Act (MACRA) in 2015 marked a fundamental transition in physician payment by the Centers for Medicare and Medicaid Services (CMS) from traditional fee-for service to value-based models. MACRA led to the creation of the CMS Quality Payment Program (QPP), which bases the value of physician care in large part on physician quality reporting. The QPP enabled a shift away from legacy CMS-stewarded quality measures that had limited applicability to individual specialties toward specialty-specific quality measures developed and stewarded by physician specialty societies using Qualified Clinical Data Registries (QCDRs). This article describes …

A Pilot Study Of Urine Proteomics In Covid-19-Associated Acute Kidney Injury, Yinyin Ye, Madhurima Kaushal, Diane Salamon, Amanda Knoten, Laura Marks, Joseph P Gaut, Anitha Vijayan, Philip A Mudd, Jane A O'Halloran, Sanjay Jain, Et Al.

2020-Current year OA Pubs

No abstract provided.

Deletion Of Type Viii Collagen Reduces Blood Pressure, Increases Carotid Artery Functional Distensibility And Promotes Elastin Deposition, Amanda L Mohabeer, Jeffrey T Kroetsch, Meghan Mcfadden, Negin Khosraviani, Thomas J Broekelmann, Guangpei Hou, Hangjun Zhang, Yu-Qing Zhou, Minyao Wang, Anthony O Gramolini, Robert P Mecham, Scott P Heximer, Steffen-Sebastian Bolz, Michelle P Bendeck

2020-Current year OA Pubs

Arterial stiffening is a significant predictor of cardiovascular disease development and mortality. In elastic arteries, stiffening refers to the loss and fragmentation of elastic fibers, with a progressive increase in collagen fibers. Type VIII collagen (Col-8) is highly expressed developmentally, and then once again dramatically upregulated in aged and diseased vessels characterized by arterial stiffening. Yet its biophysical impact on the vessel wall remains unknown. The purpose of this study was to test the hypothesis that Col-8 functions as a matrix scaffold to maintain vessel integrity during extracellular matrix (ECM) development. These changes are predicted to persist into the adult …

Unmasc: Tumor-Only Variant Calling With Unmatched Normal Controls, Paul Little, Heejoon Jo, Alan Hoyle, Angela Mazul, Xiaobei Zhao, Ashley H Salazar, Douglas Farquhar, Siddharth Sheth, Maheer Masood, Michele C Hayward, Joel S Parker, Katherine A Hoadley, Jose Zevallos, D Neil Hayes

2020-Current year OA Pubs

Despite years of progress, mutation detection in cancer samples continues to require significant manual review as a final step. Expert review is particularly challenging in cases where tumors are sequenced without matched normal control DNA. Attempts have been made to call somatic point mutations without a matched normal sample by removing well-known germline variants, utilizing unmatched normal controls, and constructing decision rules to classify sequencing errors and private germline variants. With budgetary constraints related to computational and sequencing costs, finding the appropriate number of controls is a crucial step to identifying somatic variants. Our approach utilizes public databases for canonical …

Detecting Risk Level In Individuals Misusing Fentanyl Utilizing Posts From An Online Community On Reddit, Sanjana Garg, Jordan Taylor, Mai El Sherief, Erin Kasson, Talayeh Aledavood, Raven Riordan, Nina Kaiser, Patricia Cavazos-Rehg, Munmun De Choudhury

2020-Current year OA Pubs

INTRODUCTION: Opioid misuse is a public health crisis in the US, and misuse of synthetic opioids such as fentanyl have driven the most recent waves of opioid-related deaths. Because those who misuse fentanyl are often a hidden and high-risk group, innovative methods for identifying individuals at risk for fentanyl misuse are needed. Machine learning has been used in the past to investigate discussions surrounding substance use on Reddit, and this study leverages similar techniques to identify risky content from discussions of fentanyl on this platform.

METHODS: A codebook was developed by clinical domain experts with 12 categories indicative of fentanyl …

Pharmacogenomics Insights Into Precision Pediatric Oncology, Kristie N. Ramos, David Gregornik, Kenneth S. Ramos

2020-Current year OA Pubs

PURPOSE OF REVIEW: Pharmacogenomic insights provide an opportunity to optimize medication dosing regimens and patient outcomes. However, the potential for interindividual genomic variability to guide medication dosing and toxicity monitoring is not yet standard of care. In this review, we present advances for the thiopurines, anthracyclines and vincristine and provide perspectives on the actionability of pharmacogenomic guidance in the future.

RECENT FINDINGS: The current guideline on thiopurines recommends that those with normal predicted thiopurine methyltransferase and NUDT15 expression receive standard-of-care dosing, while 'poor metabolizer' haplotypes receive a decreased 6-mercaptopurine starting dose to avoid bone marrow toxicity. Emerging evidence established significant …

Genetic Liability To Cannabis Use Disorder And Covid-19 Hospitalization, Alexander S Hatoum, Claire L Morrison, Sarah M C Colbert, Evan A Winiger, Emma C Johnson, Arpana Agrawal, Ryan Bogdan

2020-Current year OA Pubs

BACKGROUND: Vulnerability to COVID-19 hospitalization has been linked to behavioral risk factors, including combustible psychoactive substance use (e.g., tobacco smoking). Paralleling the COVID-19 pandemic crisis have been increasingly permissive laws for recreational cannabis use. Cannabis use disorder (CUD) is a psychiatric disorder that is heritable and genetically correlated with respiratory disease, independent of tobacco smoking. We examined the genetic relationship between CUD and COVID-19 hospitalization.

METHODS: We estimated the genetic correlation between CUD (case:

RESULTS: Genetic vulnerability to COVID-19 was correlated with genetic liability to CUD (

CONCLUSIONS: Problematic cannabis use and vulnerability to serious COVID-19 complications share genetic underpinnings …

Biochemical And Immuno-Histochemical Localization Of Type Iia Procollagen In Annulus Fibrosus Of Mature Bovine Intervertebral Disc, Audrey Mcalinden, David M Hudson, Aysel A Fernandes, Soumya Ravindran, Russell J Fernandes

2020-Current year OA Pubs

For next generation tissue-engineered constructs and regenerative medicine to succeed clinically, the basic biology and extracellular matrix composition of tissues that these repair techniques seek to restore have to be fully determined. Using the latest reagents coupled with tried and tested methodologies, we continue to uncover previously undetected structural proteins in mature intervertebral disc. In this study we show that the "embryonic" type IIA procollagen isoform (containing a cysteine-rich amino propeptide) was biochemically detectable in the annulus fibrosus of both calf and mature steer caudal intervertebral discs, but not in the nucleus pulposus where the type IIB isoform was predominantly …

Metastatic Castrate-Resistant Prostate Cancer: A Rare Cause Of Bowel Obstruction, Syed Ehsanullah, Syeda Zarmeena Rashid, Saiyed Abdullah A. Ehsanullah

2020-Current year OA Pubs

Prostate cancer most commonly metastasizes to bone, lymph nodes, lungs, or liver, but rarely spreads to the large intestine. This case highlights a rare case of castrate-resistant prostate cancer (CRPC) that spread locally to the large intestine and rectum, significant enough to cause bowel obstruction. Metastatic prostate carcinomas are considered an infrequent cause of bowel obstruction.

Emergency Clinicians' Perceptions Of Communication Tools To Establish The Mental Baseline Of Older Adults: A Qualitative Study, Anita Chary, Christopher Joshi, Noelle Castilla-Ojo, Ilianna Santangelo, Kei Ouchi, Aanand D. Naik, Christopher R. Carpenter, Shan W Liu, Maura Kennedy

2020-Current year OA Pubs

Background Evaluating older adults with altered mental status in emergency settings can be challenging due to the inability to obtain a history from patients directly and limited collateral information about the change from a patient's mental status baseline. Documents and videos establishing a patient's mental baseline could represent useful communication tools to aid emergency clinicians. Methods Qualitative interviews conducted with 22 emergency clinicians (12 physicians and 10 advanced practice providers) identified methods they use to determine baseline mental status of older adults in the ED and the perceived utility of document- and video-based information about an older adult's baseline mental …

Effectiveness Of Simulation-Based Clinical Skills Training For Medical Students In Respiratory Medicine: A Pilot Study, Russell S. Martins, Saniya Sabzwari, Meesha Iqbal

Medical College Documents

Objective: To assess the effectiveness of high-fidelity simulation-based medical education (HF-SBME) in teaching and learning respiratory clinical examination in medical students.
Study design: Quasi-experimental pilot study.
Place and duration of study: The Aga Khan University, Karachi, from November 2018 to January 2020. Methodology: This study was conducted amongst third year medical students at the University. Students were assigned to intervention (IG) or control groups (CG). The IG underwent training for the respiratory clinical examination on a high-fidelity simulator mannequin, while the CG received the conventional practice session on standardised patients. Students were assessed on their respiratory clinical examination skills in …

The Comparative Study Of Students’ Ability In Writing Skill Between Salaf’S And Khalaf’S Pesantren/ المقارنة بين كفائة الطلبة على الكتابة في المعهد السلفي والخلفي, Dara Mubshirah

Al-Arabi: Journal of Teaching Arabic as a Foreign Language

Arabic is one of the materials studied in Pesantren Khalafi and Salafi. Maharah Kitabah is one of the important skills in learning Arabic. The purpose of this study was to determine the extent of the differences in the kitabah ability of the students i

Teacher Talk Patterns In Online Learning Of Arabic Speaking Skills, Zahriyatun Naeli Syarof

Al-Arabi: Journal of Teaching Arabic as a Foreign Language

Classroom interaction is an important aspect in language learning, especially in speaking class. interaction occurs between lecturers and students or between students. However, at the end of 2019 there was a covid-19 outbreak around the world, so offli

Leaning Arabic Using Google Classroom/ تعلم اللغة العربية بوسيلة جوجل كلاسروم, Halimatus Sa’Diyah

Al-Arabi: Journal of Teaching Arabic as a Foreign Language

This research aims to: (1) know the university’s learning via the Internet in the Department of Language Education in Indonesia using Google Classroom, and (2) describe the advantages and disadvantages of teaching Arabic using Google Classroom. Therefo

Using Nearpod For Teaching Arabic In Kindergarten And Madrasah Ibtidaiyah, Nur Anisah Ridwan, Hanik Mahliatussikah

Al-Arabi: Journal of Teaching Arabic as a Foreign Language

The rapid development of technology lately has had a great influence on various aspects of life, including the world of education. Among them is the creation of various kinds of online learning applications in the form of games. The game application is

The Effectivity Of Himmati To Improve The Arabic Reading Skills Through The Online Atq Program, Himatul Istiqomah, Nurul Murtadho, Hanik Mahliatussikah, Yhusi Karina Riskawati, Mohammad Jawad Habeeb Al-Badrani

Al-Arabi: Journal of Teaching Arabic as a Foreign Language

This article aimed to verify the effectivity of Himmati to improve the Arabic reading skills of beginners. The target population here was all of the beginners in Indonesia as well as some other countries in Southeast Asia. While the accessible populati

The Implementation Of Preparing Test Items For The Elements Of The Arabic Language (Phonology, Vocabulary, And Structures)/ تطبيق إعداد بنود الإختبار لعناصر اللغة العربية ( الأصوات والمفردات والتراكيب ), Maftuhati Maftuhati, Nihayatin Musyafa'ah, Silmi Maulidya

Al-Arabi: Journal of Teaching Arabic as a Foreign Language

The purpose of writing this article is to implement test item preparation for language items. There are three types of this test: sounds, structures, and vocabulary. We also know that preparing test items has a very important role, because every subjec

Bibliometric Analysis Of “Jurnal Lingkungan Dan Bencana Geologi" 2016-2020 Period, Dwi Ridho Aulianto, Cut Nanda Annisa, Muhammad Aulia Taufiqi

Library Philosophy and Practice (e-journal)

This study aimed to find out more detail about the “Jurnal Lingkungan dan Bencana Geologi” which was published during 2016-2020. This was seen from the distribution of articles each year, author contributions, authorship patterns, number of pages, reference literature, and analysis of their citation. This study used bibliometric analysis as the method and the source was taken from the page http://jlbg.geologi.esdm.go.id/index.php/jlbg as data collection. The data was processed and analyzed using Ms. Excel and Publish or Perish (PoP) Application. The results of the study concluded that JLBG was published twice a year and published 75 articles during 2016-2020, those written …

Status Of College Libraries In Tripura, Augustine Zimik, Priyanka Laskar

Library Philosophy and Practice (e-journal)

Academic Libraries has always played a pivotal role in nurturing a resourceful human resource. The college library in particular introduces the importance of library in achieving decent grade in academic pursued. This paper is an attempt to understand the status of libraries and their services provided in college libraries of Tripura, India. Another major objective of the study is to investigate the status of college library professionals in the state of Tripura. For the study fourteen college libraries were considered for examination. A survey method was employed for the study. For primary data collection, questionnaires were distributed to concerned librarians. …

Level Of Disaster Management Preparedness By Library Staff In Academic Libraries: The Experience Of Academic Libraries In South Eastern States, Nigeria, Pauline Iroeze, Pauline Chinasa Iroeze Dr.

Library Philosophy and Practice (e-journal)

Abstract

Academic libraries in South-eastern Nigeria are still not prepared for disaster. This study sets out to assess the current status of preparedness in disaster management among academic libraries in the South east geopolitical zone of Nigeria. To obtain a base level of knowledge on disaster preparedness of current practices, a questionnaire was distributed to 380 librarians at 5 academic libraries, 356 responses were received and after sorting 337 were found to be usable. The study revolved around the current status of preparedness, on various issues including major threats that could possibly cause disaster, existence of disaster preparedness plan among …

Access To E-Resources By Librarians In University Libraries In Niger Delta Region, Nigeria, Vincent Osamuyimen Ekhaguosa, Mary Irughe, Efosa Egharevba

Library Philosophy and Practice (e-journal)

This study investigated Access to Electronic Resources by Librarians in University Libraries in Niger Delta Region, Nigeria. The descriptive research design was adopted for this study using 73 items self-structured questionnaire to collect data. In selecting the university libraries, the researcher applied the stratified random sampling technique to select the universities. One hundred and fifty (150) librarians were selected from three (3) centrally located states which include Delta, Bayelsa, and Edo from the nine (9) Niger Delta States from a target population of four hundred and thirty-two (432) librarians. seven research questions were formulated to guide the study. A reliability …

Supply Chain In Library: A Bibliometric Analysis, Ria Arifianti, Abdurrahman Rahim Thaha, Taharuddin Taharuddin

Library Philosophy and Practice (e-journal)

The research objective of this paper is to identify and map supply chain research in a library. This study conducted a bibliometric analysis using the Scopus electronic database. The article search is done by filtering search results in the system and manual exploration to get relevant articles. The collected articles are processed with the VOSviewer application to obtain research mapping results. A total of 81 articles were obtained from 1999 to 2021, with an increasing trend in the number of articles each year. The United States and China are the most productive countries in this field. Three cluster topics were …

Perspectives Of Knowledge Management Systems Implementation, De-Graft Johnson Dei

Library Philosophy and Practice (e-journal)

The implementation of systems to manage the knowledge of organizations requires robust technical and non-technical support in other to be successful. Knowledge management systems integrate people, processes, and technology. These systems result in changes in the operations and processes in organizations. The study assessed knowledge management systems from the two main perspectives (technical and non-technical) by emphasizing the technologies that drive the creation, processing, sharing, and storage of knowledge. From the nontechnological perspective, the study focussed on the interaction of people, process and that promote KM. This paved the way for the discussion of the various perspectives or procedures for …

Field Evaluation Of A New Third Generation Push-Pull Technology For Control Of Striga Weed, Stemborers, And Fall Armyworm In Western Kenya, Duncan Cheruiyot, Frank Chidawanyika, Charles A.O. Midega, Jimmy O. Pittchar, John A. Pickett, Zeyaur R. Khan

All Peer-Reviewed Publications

Production of cereal crops in sub-Saharan Africa is threatened by parasitic striga weeds and attack by stemborers and the invasive fall armyworm (FAW), compounded by increasing hot and dry conditions. A climate-smart push-pull technology (PPT) significantly reduces effects of these biotic challenges. To improve further resilience of the system to climate change, more adapted and suitable companion plants were identified and integrated in a new version of PPT, termed 'third generation PPT'. Our study evaluates field performance and farmer opinions of this new version in comparison with the earlier version, climate-smart PPT, and farmers' own practices of growing maize in …

Temperature-Dependent Modelling And Spatial Prediction Reveal Suitable Geographical Areas For Deployment Of Two Metarhizium Anisopliae Isolates For Tuta Absoluta Management, Ayaovi Agbessenou, Komivi S. Akutse, Abdullahi A. Yusuf, Sospeter W. Wekesa, Fathiya M. Khamis

All Peer-Reviewed Publications

Tuta absoluta is one of the most devastating pests of Solanaceae crops in Africa. We previously demonstrated the efficacy of Metarhizium anisopliae isolates ICIPE 18, ICIPE 20 and ICIPE 665 against adult T. absoluta. However, adequate strain selection and accurate spatial prediction are fundamental to optimize their efficacy and formulations before field deployment. This study therefore assessed the thermotolerance, conidial yield and virulence (between 15 and 35 °C) of these potent isolates. Over 90% of conidia germinated at 20, 25 and 30 °C while no germination occurred at 15 °C. Growth of the three isolates occurred at all temperatures, but …

Molecular Prevalence And Risk Factors Associated With Tick-Borne Pathogens In Cattle In Western Kenya, Tatenda Chiuya, Jandouwe Villinger, Daniel K. Masiga, Dickens O. Ondifu, Maurice K. Murungi, Lillian Wambua, Armanda D.S. Bastos, Eric M. Fèvre, Laura C. Falzon

All Peer-Reviewed Publications

Background: Tick-borne pathogens (TBPs) are of global importance, especially in sub-Saharan Africa where they represent a major constraint to livestock production. Their association with human disease is also increasingly recognized, signalling their zoonotic importance. It is therefore crucial to investigate TBPs prevalence in livestock populations and the factors associated with their presence. We set out to identify TBPs present in cattle and to determine associated risk factors in western Kenya, where smallholder livestock production is important for subsistence and market-driven income. Results: Tick-borne pathogen infections in blood samples collected from cattle at livestock markets and slaughterhouses between May 2017 and …

Correction To: 2021 Taxonomic Update Of Phylum Negarnaviricota (Riboviria: Orthornavirae), Including The Large Orders Bunyavirales And Mononegavirales (Archives Of Virology, (2021), 166, 12, (3513-3566), 10.1007/S00705-021-05143-6), Jens H. Kuhn, Scott Adkins, Bernard R. Agwanda, Rim Al Kubrusli, Sergey V. Alkhovsky, Gaya K. Amarasinghe, Tatjana Avšič-Županc, María A. Ayllón, Justin Bahl, Anne Balkema-Buschmann, Matthew J. Ballinger, Christopher F. Basler, Sina Bavari, Martin Beer, Nicolas Bejerman, Andrew J. Bennett, Dennis A. Bente, Éric Bergeron, Brian H. Bird, Carol D. Blair, Kim R. Blasdell, Dag Ragnar Blystad, Jamie Bojko, Wayne B. Borth, Steven Bradfute, Rachel Breyta, Thomas Briese, Paul A. Brown

All Peer-Reviewed Publications

Unfortunately, the inclusion of original names (in non-Latin script) of the following authors caused problems with author name indexing in PubMed. Therefore, these original names were removed from XML data to correct the PubMed record. Mengji Cao, Yuya Chiaki, Hideki Ebihara, Jingjing Fu, George Fú Gāo, Tong Han, Jiang Hong, Ni Hong, Seiji Hongo, Masayuki Horie, Dàohóng Jiāng, Fujio Kadono, Hideki Kondō, Kenji Kubota, Shaorong Li, Longhui Li, Jiànróng Lǐ, Huazhen Liu, Tomohide Natsuaki, Sergey V. Netesov, Anna Papa, Sofia Paraskevopoulou, Liying Qi, Takahide Sasaya, Mang Shi, Xiǎohóng Shí, Zhènglì Shí, Yoshifumi Shimomoto, Jin‑Won Song, Ayato Takada, Shigeharu Takeuchi, Yasuhiro …