Digital Commons Network^™

Genomic Analysis Reveals Independent Evolution Of Plasmodium Falciparum Populations In Ethiopia, Deriba Abera, Caleb K. Kibet, Teshome Degefa, Lucas Amenga-Etego, Joel L. Bargul, Lemu Golassa

All Peer-Reviewed Publications

Background: Plasmodium falciparum parasite populations in Ethiopia have been experiencing local selective pressures from drugs and immunity, leading to evolutionary adaptation. However, there was a paucity of data on genomic characterization and evolutionary adaptations of P. falciparum isolates from the central area of Ethiopia. Methods: Whole-genome analysis of 25 P. falciparum isolates from central Ethiopia, specifically from West Arsi, were studied to determine their genetic diversity, population structures, and signatures of selection in known drug resistance alleles against global isolates from Cambodia, Thailand, DR Congo, and Malawi. Results: A total of 18,517 high-quality single-nucleotide polymorphisms (SNPs) were identified in Ethiopian …

Evaluation Of Health Surveillance System Attributes: The Case Of Neglected Tropical Diseases In Kenya, Arthur K.S. Ng’Etich, Kuku Voyi, Clifford M. Mutero

All Peer-Reviewed Publications

Background: Control of preventive chemotherapy-targeted neglected tropical diseases (PC-NTDs) relies on strengthened health systems. Efficient health information systems provide an impetus to achieving the sustainable development goal aimed at ending PC-NTD epidemics. However, there is limited assessment of surveillance system functions linked to PC-NTDs and hinged on optimum performance of surveillance system attributes. The study aimed to evaluate surveillance system attributes based on healthcare workers’ perceptions in relation to PC-NTDs endemic in Kenya. Methods: A cross-sectional health facility survey was used to purposively sample respondents involved in disease surveillance activities. Consenting respondents completed a self-administered questionnaire that assessed their perceptions …

Water Immersion Tolerance By Larval Instars Of Stable Fly, Stomoxys Calcitrans, L1758 (Diptera: Muscidae) Impairs The Fitness Performance Of Their Subsequent Stages, Steve B.S. Baleba

All Peer-Reviewed Publications

Background: In holometabolous insects, environmental factors experienced in pre-imaginal life stages affect the life-history traits within that stage and can also influence subsequent life stages. Here, I assessed tolerance to water immersion by the larval instars of the stable fly, Stomoxys calcitrans L. (Diptera: Muscidae) and its impact on the life-history traits of their subsequent life stages. Results: After submerging the three larval instars of S. calcitrans in distilled water, I found that the first instar larvae remained active for longer as compared to the second and third instar larvae. Also, the first instar larvae took a longer period to …

Ehrlichia Spp. Close To Ehrlichia Ruminantium, Ehrlichia Canis, And “Candidatus Ehrlichia Regneryi” Linked To Heartwater-Like Disease In Kenyan Camels (Camelus Dromedarius), Mario Younan, Daniel O. Ouso, Boku Bodha, Edward K. Keitany, Hezron O. Wesonga, Rinah Sitawa, Joshua Kimutai, Wilson Kuria, Wario Sori Sake, Nicholas Svitek, Tobias Landmann, Diba Dida Wako, Jandouwe Villinger

All Peer-Reviewed Publications

We present findings from an outbreak of a heartwater-like disease in camels that killed at least 2000 adult animals in Kenya in 2016. Clinical signs included excitability, head pressing, aimless wandering, recumbency, and fast breathing followed by death after about 4 days. The observed morbidity in one herd was 40% with an average mortality of 7.5% in animals that received early antibiotic treatments. In untreated adults, the case fatality rate reached 100%. Gross pathology showed pulmonary edema, pleural exudate, hydrothorax, hydropericardium, ascites, enlarged “cooked” liver, nephrosis, and blood in the abomasum and intestine. Using established PCR-based protocols for tick-borne pathogens, …

Molecular Detection Of Leishmania Donovani, Leishmania Major, And Trypanosoma Species In Sergentomyia Squamipleuris Sand Flies From A Visceral Leishmaniasis Focus In Merti Sub-County, Eastern Kenya, Barrack O. Owino, Jackline Milkah Mwangi, Steve Kiplagat, Hannah Njiriku Mwangi, Johnstone M. Ingonga, Alphine Chebet, Philip M. Ngumbi, Jandouwe Villinger, Daniel K. Masiga, Damaris Matoke-Muhia

All Peer-Reviewed Publications

Background: Visceral leishmaniasis (VL) and zoonotic cutaneous leishmaniasis (ZCL) are of public health concern in Merti sub-County, Kenya, but epidemiological data on transmission, vector abundance, distribution, and reservoir hosts remain limited. To better understand the disease and inform control measures to reduce transmission, we investigated the abundance and distribution of sand fly species responsible for Leishmania transmission in the sub-County and their blood-meal hosts. Methods: We conducted an entomological survey in five villages with reported cases of VL in Merti sub-County, Kenya, using CDC miniature light traps and castor oil sticky papers. Sand flies were dissected and identified to the …

Climate Change And Specialty Coffee Potential In Ethiopia, Abel Chemura, Bester Tawona Mudereri, Amsalu Woldie Yalew, Christoph Gornott

All Peer-Reviewed Publications

Current climate change impact studies on coffee have not considered impact on coffee typicities that depend on local microclimatic, topographic and soil characteristics. Thus, this study aims to provide a quantitative risk assessment of the impact of climate change on suitability of five premium specialty coffees in Ethiopia. We implement an ensemble model of three machine learning algorithms to predict current and future (2030s, 2050s, 2070s, and 2090s) suitability for each specialty coffee under four Shared Socio-economic Pathways (SSPs). Results show that the importance of variables determining coffee suitability in the combined model is different from those for specialty coffees …

Mitogenomic Analysis Of Diversity Of Key Whitefly Pests In Kenya And Its Implication To Their Sustainable Management, Fathiya M. Khamis, Fidelis L.O. Ombura, Inusa J. Ajene, Komivi S. Akutse, Sevgan Subramanian, Samira A. Mohamed, Thomas Dubois, Chrysantus M. Tanga, Sunday Ekesi

All Peer-Reviewed Publications

Whiteflies (Hemiptera: Aleyrodidae) are devastating agricultural pests of economic importance vectoring pathogenic plant viruses. Knowledge on their diversity and distribution in Kenya is scanty, limiting development of effective sustainable management strategies. The present study is aimed at identifying whitefly pest species present in Kenya across different agroecological zones and establish predictive models for the most abundant species in Africa. Whiteflies were sampled in Kenya from key crops known to be severely infested and identified using 16S rRNA markers and complete mitochondrial genomes. Four whitefly species were identified: Aleyrodes proletella, Aleurodicus dispersus, Bemisia afer and Trialeurodesvaporariorum, the latter being the most …

Assessment Of Surveillance Core And Support Functions Regarding Neglected Tropical Diseases In Kenya, Arthur K.S. Ng’Etich, Kuku Voyi, Clifford M. Mutero

All Peer-Reviewed Publications

Background: Effective surveillance and response systems are vital to achievement of disease control and elimination goals. Kenya adopted the revised guidelines of the integrated disease surveillance and response system in 2012. Previous assessments of surveillance system core and support functions in Africa are limited to notifiable diseases with minimal attention given to neglected tropical diseases amenable to preventive chemotherapy (PC-NTDs). The study aimed to assess surveillance system core and support functions relating to PC-NTDs in Kenya. Methods: A mixed method cross-sectional survey was adapted involving 192 health facility workers, 50 community-level health workers and 44 sub-national level health personnel. Data …

Insect Flower-Visitors Of African Oil Palm Elaeis Guineensis At Different Sites And Distances From Natural Vegetation In Uganda, James Peter Egonyu, Stephen Erisa Sisye, John Baguma, Milton Otema, Gabriel Ddamulira

All Peer-Reviewed Publications

This survey aimed at generating information to guide improvement of oil palm fruit-set in Uganda by testing the hypothesis that diversity and abundance of oil palm insect flower-visitors were influenced by sampling site, distance from natural vegetation and flower sex. Sampling was done on male and female oil palm flowers from (i) five oil palm experimental fields in different districts and (ii) oil palm plantations on Bugala Island on Lake Victoria. The plantations on Bugala Island were subdivided into near (0–15 m) and far (100–200 m) from natural vegetation. We recorded 162,677 insects in 23 morpho-species, dominated by weevils in …

Gene Co-Expression Network Analysis Of Trypanosoma Brucei In Tsetse Fly Vector, Kennedy W. Mwangi, Rosaline W. Macharia, Joel L. Bargul

All Peer-Reviewed Publications

Background: Trypanosoma brucei species are motile protozoan parasites that are cyclically transmitted by tsetse fly (genus Glossina) causing human sleeping sickness and nagana in livestock in sub-Saharan Africa. African trypanosomes display digenetic life cycle stages in the tsetse fly vector and in their mammalian host. Experimental work on insect-stage trypanosomes is challenging because of the difficulty in setting up successful in vitro cultures. Therefore, there is limited knowledge on the trypanosome biology during its development in the tsetse fly. Consequently, this limits the development of new strategies for blocking parasite transmission in the tsetse fly. Methods: In this study, RNA-Seq …

Transcriptomic Response Of Anopheles Gambiae Sensu Stricto Mosquito Larvae To Curry Tree (Murraya Koenigii) Phytochemicals, Clarence M. Mang’Era, Fathiya M. Khamis, Erick O. Awuoche, Ahmed Hassanali, Fidelis Levi Odhiambo Ombura, Paul O. Mireji

All Peer-Reviewed Publications

Background: Insect growth regulators (IGRs) can control insect vector populations by disrupting growth and development in juvenile stages of the vectors. We previously identified and described the curry tree (Murraya koenigii (L.) Spreng) phytochemical leaf extract composition (neplanocin A, 3-(1-naphthyl)-l-alanine, lumiflavine, terezine C, agelaspongin and murrayazolinol), which disrupted growth and development in Anopheles gambiae sensu stricto mosquito larvae by inducing morphogenetic abnormalities, reducing locomotion and delaying pupation in the mosquito. Here, we attempted to establish the transcriptional process in the larvae that underpins these phenotypes in the mosquito. Methods: We first exposed third-fourth instar larvae of the mosquito to the …

Plant Nutrient Quality Impacts Survival And Reproductive Fitness Of The Dengue Vector Aedes Aegypti, Vincent Odhiambo Nyasembe, David Poumo Tchouassi, Martha Njeri Muturi, Christian W.W. Pirk, Catherine L. Sole, Baldwyn Torto

All Peer-Reviewed Publications

Background: In a recent study using DNA barcoding, we identified the plants fed upon by four Afro-tropical mosquito species that vector dengue, malaria, and Rift Valley fever. Herein, we have expanded on this study by investigating the role of three of the plants, Pithecellobium dulce (Fabaceae), Leonotis nepetifolia (Lamiaceae), and Opuntia ficus-indica (Cactaceae), on the survival, fecundity, and egg viability of the dengue vector Aedes aegypti. Methods: We tested these effects using females that received (i) an initial three rations of blood meals and (ii) no blood meal at all. Two controls were included: age-matched females fed on glucose solution …

The Pacifican December 2021, University Of The Pacific

All Issues - Student Newspaper, The Pacifican, Pacific Weekly

No abstract provided.

Front Matter

The Foundation Review

No abstract provided.

Full Issue

The Foundation Review

No abstract provided.

Editorial, Teresa R. Behrens

The Foundation Review

No abstract provided.

Doing Philanthropy At The Time Of The Sustainable Development Goals: The Case Of Fondazione Compagnia Di San Paolo, Fulvio Bersanetti, Filippo Candela, Paolo Mulassano

The Foundation Review

This article outlines how strategic philanthropy can align its mission with the United Nations 2030 Agenda for Sustainable Development by describing the experience of the most important foundation of banking origin in Italy. Fondazione Compagnia di San Paolo marked a milestone in 2020 in aligning with the Agenda, applying the Sustainable Development Goals as a rigorous, internationally shared methodological framework and restructuring its operations to focus on three programmatic efforts — Planet, People, and Culture — aligned with those goals.

To complete our examination of this transformation, we conducted a benchmark analysis involving nine case studies of foundations in Europe …

Back Matter

The Foundation Review

No abstract provided.

Walking The Talk On Sustainable Development Goals: The Case Of Community Foundations In Canada, Marta Rey-Garcia, Rosane Dal Magro

The Foundation Review

The United Nations 2030 Agenda creates an opportunity for philanthropic foundations to become more collaborative and transformative in their work toward global goals. Thus, since 2016, the extent to which foundations adopt the Sustainable Development Goals framework in their functioning has become a topic of interest. Although survey- and case-based research shows increased rates of self-reported adoption and several tools are available to help foundations to act toward the goals, there is a lack of systematic evidence about the purposes of and processes for adopting the goals among foundations.

This void is particularly relevant for community foundations, as they have …

A Case Study On The Use Of The Sdgs With A Collective Impact Initiative In Southwest Florida, Tessa Lesage, Aysegul Timur, Dakota Pawlicki

The Foundation Review

The United Nations Sustainable Development Goals can be a useful framework on which to design, evaluate, and communicate collective impact initiatives. Using as a case study the FutureMakers Coalition, a collective impact initiative launched by the Southwest Florida Community Foundation to transform its region’s workforce, the field can gain insights into how the goals can strengthen collective impact work locally and nationally.

This article will discuss how the foundation facilitated the setting of a common agenda and the use of the Sustainable Development Goals to help build consensus among 251 active partners on how to measure progress toward the coalition’s …

Where To Start? A Tool For Thinking About The Sdgs And Community Foundation Work, Katie Leone, Tessa Lesage

The Foundation Review

The merits of advancing the United Nations Sustainable Development Goals are widely agreed upon by the global community, but designing and applying strategies to do so at the local level can be challenging. This article aims to support community foundations in moving the 2030 Agenda for Sustainable Development forward in practical ways by exploring the use of a point-of-entry wheel to create a shared language that can help community foundations align their local efforts with the global goals.

Since 2012, Collaboratory has been exploring the potential for integrating sustainability — encompassing economic, social, and environmental pillars — as a strategic …

Socially Distant Signing: Why Georgia Should Adopt Remote Will Execution In The Post-Covid World, Jessie Daniel Rankin

Georgia Law Review

In the wake of the COVID-19 pandemic, Georgia Governor Brian Kemp and other state governors issued emergency executive orders authorizing the attestation and execution of wills, trusts, and other testamentary documents through the use of audio-video technology. Most states have traditionally required that such testamentary documents be signed in the physical presence of two or more witnesses to be valid. Georgia’s executive order permits these witnesses to instead observe the signing via video-conferencing software, alleviating the requirement that the witnesses be physically present with the testator. This authorization, however, only exists through this executive order and could lapse or be …

Polynomial Embeddings Of Unilateral Weighted Shifts In 2-Variable Weighted Shifts, Raul E. Curto, Sang H. Lee, Jasang Yoon

School of Mathematical & Statistical Sciences Faculty Publications

Given a bounded sequence omega of positive numbers, and its associated unilateral weighted shift W-omega, acting on the Hilbert space l(2) (Z+), we consider natural representations of W-omega as a 2-variable weighted shift, acting on the Hilbert space l(2)(Z(+)(2)). Alternatively, we seek to examine the various ways in which the sequence omega can give rise to a 2-variable weight diagram, corresponding to a 2-variable weighted shift. Our best (and more general) embedding arises from looking at two polynomials p and q nonnegative on a closed interval I subset of R+ and the double-indexed moment sequence {integral p(r)(k) q(r)(l) d sigma(r)}(k,l …

Exegesis: Mark 6:30-44, Younggwang Kim

Masters Theses

Jesus’ feeding the five thousand is the only miracle that the four Gospels commonly recorded among the miracles Jesus Himself performed. The feeding miracle episode is like the gem, which changes light colors slightly depending on how people see it. However, some scholars try to approach it only in a particular direction and partially understand it. Based on the literary-historical-theological methodology, this thesis has a focal point to disclose the compressive and multi-dimensional implications. The exegesis of Mark 6:30-44 begins with the refinement of interpretive methodology. The methodology of this thesis prudently considers both the traditional perspective and recent research. …

Reflip Type: Developing Visual Strategies For Teaching Typography To Collegiate Students With Dyslexia, Brittany D. Strozzo

Masters Theses

In educational facilities today, the approaches to teaching typography to college students with dyslexia are limited. This thesis provides a research-based pedagogy for teaching typography to students in a way that accommodates the visual, processing, and auditory differences present in students with dyslexia. Through the analysis of the learning disability itself, existing material for graphic designers with dyslexia, and current accessibility standards for those with dyslexia, this thesis offers a practical solution to provide a more balanced learning experience for all students, especially those with dyslexia. The aim of this study was to examine the current graphic design standards and …

And The Lord Added To Their Number Daily: A Historical Overview Of The Growth Of The American Evangelical Church, Erica Morgan Wrench

Masters Theses

Serving Special Education Students In The Music Classroom: Accommodating And Advocating For Learners With Exceptionalities, Kathryn Lambert

Masters Theses

Music education programs positively impact the lives of students both socially and emotionally. As the following research suggests, music may have an even greater impact on students with disabilities or exceptionalities. Due to the lack of accessibility, funding, time, training, and other issues, opportunities in music education programs may be limited to groups of students who may not fit the standard music education student profile. As teachers of common core classes may struggle to accommodate students with exceptionalities and may feel as if they are lacking in resources or other needed preparation to adequately serve these students, these struggles are …

Tomb And Temple : The Poet’S Use Of Positive Body Imagery To Communicate Messages Of Psychological Wellbeing, Shelby Elizabeth Poulin

Masters Theses

Mary Oliver writes that imagery is the texture of a poem, and the “detailed, sensory language incorporating images . . . gives the poem dash and tenderness” (Oliver 92). Imagery brings poetry to life, offering the reader a whole-body experience over simple description. Oliver cautions, however, that imagery is powerful and should be used responsibility, further implying that this texture can also become jolting, harsh, or offensive if used incorrectly (Oliver 107-108). With this caution in mind, the purpose of my forty-six poem collection—Tomb and Temple: Letters to the Body—is to use images of the body responsibly, in a way …

Curriculum Framework For Composing And Arranging For Contemporary A Cappella Choirs, Hillary Nicole Goodson-Spear

Masters Theses

As vocalists, it is important for us to understand techniques regarding current styles of vocal composing and arranging including voicing, beat boxing, and body percussion. The success of several mainstream television programs such as Glee and The Sing-Off, popular movies franchises like Pitch Perfect, and groups like Pentatonix and Straight No Chaser, demonstrate the rising popularity of contemporary a cappella music. It also reflects the need to be able to write unique arrangements of traditional or popular songs to keep up with recent trends. Current research suggests that there are very few resources available for music educators to teach this …

Patrick Henry And John Jay: True Patriots And Advocates For Civil And Religious Liberty, Nancy Lynn Greenwood

Masters Theses

Patrick Henry and John Jay had a significant impact in the founding of the United States of America as two of the principal and most influential Founders. They were also among the most public Christians of all the Founding Fathers. Their dedication in their fight for civic and religious freedom as a means to maintaining liberty was well-known. Despite these similarities, they opposed each other on most every major issue. Each envisioned different governments in which to obtain liberty and to keep the American republic. This thesis seeks to explore the differences and similarities between Henry, as a leader of …